JBC -- Table of Contents (Sep 8 2000, 275, (36))

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Accelerated Publications:

Brian J. Nickoloff, Vijaya Chaturvedi, Patricia Bacon, Jian-Zhong Qin, Mitchell F. Denning, and Manuel O. Diaz: Id-1 Delays Senescence but Does Not Immortalize Keratinocytes
J. Biol. Chem. 2000 275: 27501-27504. [Abstract] [Full Text] [PDF]

DNA: Replication Repair and Recombination:

Tapas K. Hazra, Tadahide Izumi, Radhika Venkataraman, Yoke W. Kow, Miral Dizdaroglu, and Sankar Mitra: Characterization of a Novel 8-Oxoguanine-DNA Glycosylase Activity in Escherichia coli and Identification of the Enzyme as Endonuclease VIII
J. Biol. Chem. 2000 275: 27762-27767. [Abstract] [Full Text] [PDF]

Mark Berardini, Anthony Mazurek, and Richard Fishel: The Effect of O⁶-Methylguanine DNA Adducts on the Adenosine Nucleotide Switch Functions of hMSH2-hMSH6 and hMSH2-hMSH3
J. Biol. Chem. 2000 275: 27851-27857. [Abstract] [Full Text] [PDF]

Maria J. Jezewska, Surendran Rajendran, and Wlodzimierz Bujalowski: Escherichia coli Replicative Helicase PriA Protein-Single-stranded DNA Complex. STOICHIOMETRIES, FREE ENERGY OF BINDING, AND COOPERATIVITIES
J. Biol. Chem. 2000 275: 27865-27873. [Abstract] [Full Text] [PDF]

Wendy P. Osheroff, William A. Beard, Shang Yin, Samuel H. Wilson, and Thomas A. Kunkel: Minor Groove Interactions at the DNA Polymerase $beta$ Active Site Modulate Single-base Deletion Error Rates
J. Biol. Chem. 2000 275: 28033-28038. [Abstract] [Full Text] [PDF]

Genes: Structure and Regulation:

Robert J. Turner, Martha Lovato, and Paul Schimmel: One of Two Genes Encoding Glycyl-tRNA Synthetase in Saccharomyces cerevisiae Provides Mitochondrial and Cytoplasmic Functions
J. Biol. Chem. 2000 275: 27681-27688. [Abstract] [Full Text] [PDF]

Jawed Alam, Claire Wicks, Daniel Stewart, Pengfei Gong, Cheri Touchard, Sherrie Otterbein, Augustine M. K. Choi, Matthew E. Burow, and Jen-sie Tou: Mechanism of Heme Oxygenase-1 Gene Activation by Cadmium in MCF-7 Mammary Epithelial Cells. ROLE OF p38 KINASE AND Nrf2 TRANSCRIPTION FACTOR
J. Biol. Chem. 2000 275: 27694-27702. [Abstract] [Full Text] [PDF]

Stacey K. Ogden, Kathleen C. Lee, and Michelle Craig Barton: Hepatitis B Viral Transactivator HBx Alleviates p53-mediated Repression of $alpha$ -Fetoprotein Gene Expression
J. Biol. Chem. 2000 275: 27806-27814. [Abstract] [Full Text] [PDF]

Gerard Elberg, Jeffrey M. Gimble, and Sophia Y. Tsai: Modulation of the Murine Peroxisome Proliferator-activated Receptor $gamma$ 2 Promoter Activity by CCAAT/Enhancer-binding Proteins
J. Biol. Chem. 2000 275: 27815-27822. [Abstract] [Full Text] [PDF]

Oliver E. Bläsing, Peter Westhoff, and Per Svensson: Evolution of C4 Phosphoenolpyruvate Carboxylase in Flaveria, a Conserved Serine Residue in the Carboxyl-terminal Part of the Enzyme Is a Major Determinant for C4-specific Characteristics
J. Biol. Chem. 2000 275: 27917-27923. [Abstract] [Full Text] [PDF]

Stephan Herzig, Laszlo Füzesi, and Willhart Knepel: Heterodimeric Pbx-Prep1 Homeodomain Protein Binding to the Glucagon Gene Restricting Transcription in a Cell Type-dependent Manner
J. Biol. Chem. 2000 275: 27989-27999. [Abstract] [Full Text] [PDF]

Hiroyasu Inoue, Tadashi Tanabe, and Kazuhiko Umesono: Feedback Control of Cyclooxygenase-2 Expression through PPAR $gamma$
J. Biol. Chem. 2000 275: 28028-28032. [Abstract] [Full Text] [PDF]

Rodolfo Ghirlando and Cecelia D. Trainor: GATA-1 Bends DNA in a Site-independent Fashion
J. Biol. Chem. 2000 275: 28152-28156. [Abstract] [Full Text] [PDF]

Cecelia D. Trainor, Rodolfo Ghirlando, and Melanie A. Simpson: GATA Zinc Finger Interactions Modulate DNA Binding and Transactivation
J. Biol. Chem. 2000 275: 28157-28166. [Abstract] [Full Text] [PDF]

Felix H. Brembeck and Anil K. Rustgi: The Tissue-dependent Keratin 19 Gene Transcription Is Regulated by GKLF/KLF4 and Sp1
J. Biol. Chem. 2000 275: 28230-28239. [Abstract] [Full Text] [PDF]

Philippe Costet, Yi Luo, Nan Wang, and Alan R. Tall: Sterol-dependent Transactivation of the ABC1 Promoter by the Liver X Receptor/Retinoid X Receptor
J. Biol. Chem. 2000 275: 28240-28245. [Abstract] [Full Text] [PDF]

Nobuhiro Nakamura, Yoshiro Suzuki, Yugo Ikeda, Michitaka Notoya, and Shigehisa Hirose: Complex Structure and Regulation of Expression of the Rat Gene for Inward Rectifier Potassium Channel Kir7.1
J. Biol. Chem. 2000 275: 28276-28284. [Abstract] [Full Text] [PDF]

Daniel Robyr, Anne Gegonne, Alan P. Wolffe, and Walter Wahli: Determinants of Vitellogenin B1 Promoter Architecture. HNF3 AND ESTROGEN RESPONSIVE TRANSCRIPTION WITHIN CHROMATIN
J. Biol. Chem. 2000 275: 28291-28300. [Abstract] [Full Text] [PDF]

Mark S. Carter and Peter Sarnow: Distinct mRNAs That Encode La Autoantigen Are Differentially Expressed and Contain Internal Ribosome Entry Sites
J. Biol. Chem. 2000 275: 28301-28307. [Abstract] [Full Text] [PDF]

RNA: Structure Metabolism and Catalysis:

Yu-xin Xu, Li Liu, and Shulamit Michaeli: Functional Analyses of Positions across the 5' Splice Site of the Trypanosomatid Spliced Leader RNA. IMPLICATIONS FOR BASE-PAIR INTERACTION WITH U5 AND U6 snRNAs
J. Biol. Chem. 2000 275: 27883-27892. [Abstract] [Full Text] [PDF]

Gregory J. Warner, Marla J. Berry, Mohamed E. Moustafa, Bradley A. Carlson, Dolph L. Hatfield, and Jerry R. Faust: Inhibition of Selenoprotein Synthesis by Selenocysteine tRNA^[Ser]Sec Lacking Isopentenyladenosine
J. Biol. Chem. 2000 275: 28110-28119. [Abstract] [Full Text] [PDF]

Protein Synthesis Post-Translation Modification and Degradation:

Naushad Ali, Ger J. M. Pruijn, Daniel J. Kenan, Jack D. Keene, and Aleem Siddiqui: Human La Antigen Is Required for the Hepatitis C Virus Internal Ribosome Entry Site-mediated Translation
J. Biol. Chem. 2000 275: 27531-27540. [Abstract] [Full Text] [PDF]

Helena Vihinen and Juhani Saarinen: Phosphorylation Site Analysis of Semliki Forest Virus Nonstructural Protein 3
J. Biol. Chem. 2000 275: 27775-27783. [Abstract] [Full Text] [PDF]

Robert Stad, Yolande F. M. Ramos, Natalie Little, Shula Grivell, Joline Attema, Alex J. van der Eb, and Aart G. Jochemsen: Hdmx Stabilizes Mdm2 and p53
J. Biol. Chem. 2000 275: 28039-28044. [Abstract] [Full Text] [PDF]

Protein Structure and Folding:

Daniela M. Oliveira, Clóvis R. Nakaie, Aurea D. Sousa, Chuck S. Farah, and Fernando C. Reinach: Mapping the Domain of Troponin T Responsible for the Activation of Actomyosin ATPase Activity. IDENTIFICATION OF RESIDUES INVOLVED IN BINDING TO ACTIN
J. Biol. Chem. 2000 275: 27513-27519. [Abstract] [Full Text] [PDF]

T. Sakari Jokiranta, Jens Hellwage, Vesa Koistinen, Peter F. Zipfel, and Seppo Meri: Each of the Three Binding Sites on Complement Factor H Interacts with a Distinct Site on C3b
J. Biol. Chem. 2000 275: 27657-27662. [Abstract] [Full Text] [PDF]

Jing-fei Dong, Alicia J. Schade, Gabriel M. Romo, Robert K. Andrews, Shan Gao, Larry V. McIntire, and José A. López: Novel Gain-of-function Mutations of Platelet Glycoprotein Ib $alpha$ by Valine Mutagenesis in the Cys²⁰⁹-Cys²⁴⁸ Disulfide Loop. FUNCTIONAL ANALYSIS UNDER STATIC AND DYNAMIC CONDITIONS
J. Biol. Chem. 2000 275: 27663-27670. [Abstract] [Full Text] [PDF]

Aichun Dong, Theodore W. Randolph, and John F. Carpenter: Entrapping Intermediates of Thermal Aggregation in $alpha$ -Helical Proteins with Low Concentration of Guanidine Hydrochloride
J. Biol. Chem. 2000 275: 27689-27693. [Abstract] [Full Text] [PDF]

Helen R. Palmer, Jennifer J. Bedford, John P. Leader, and Robin A. J. Smith: ³¹P and ¹H NMR Studies of the Effect of the Counteracting Osmolyte Trimethylamine-N-oxide on Interactions of Urea with Ribonuclease A
J. Biol. Chem. 2000 275: 27708-27711. [Abstract] [Full Text] [PDF]

Keng-Mean Lin, Marisan Mejillano, and Helen L. Yin: Ca²⁺ Regulation of Gelsolin by Its C-terminal Tail
J. Biol. Chem. 2000 275: 27746-27752. [Abstract] [Full Text] [PDF]

Jon Nield, Olaf Kruse, Jonathan Ruprecht, Paula da Fonseca, Claudia Büchel, and James Barber: Three-dimensional Structure of Chlamydomonas reinhardtii and Synechococcus elongatus Photosystem II Complexes Allows for Comparison of Their Oxygen-evolving Complex Organization
J. Biol. Chem. 2000 275: 27940-27946. [Abstract] [Full Text] [PDF]

Takaki Koide, Akiko Aso, Tetuya Yorihuzi, and Kazuhiro Nagata: Conformational Requirements of Collagenous Peptides for Recognition by the Chaperone Protein HSP47
J. Biol. Chem. 2000 275: 27957-27963. [Abstract] [Full Text] [PDF]

Hiroshi Yamashita, Matt J. Tyska, David M. Warshaw, Susan Lowey, and Kathleen M. Trybus: Functional Consequences of Mutations in the Smooth Muscle Myosin Heavy Chain at Sites Implicated in Familial Hypertrophic Cardiomyopathy
J. Biol. Chem. 2000 275: 28045-28052. [Abstract] [Full Text] [PDF]

Samuel Tranier, Anne-Typhaine Bouthors, Laurent Maveyraud, Valérie Guillet, Wladimir Sougakoff, and Jean-Pierre Samama: The High Resolution Crystal Structure for Class A $beta$ -Lactamase PER-1 Reveals the Bases for Its Increase in Breadth of Activity
J. Biol. Chem. 2000 275: 28075-28082. [Abstract] [Full Text] [PDF]

Nasim Mavaddat, Don W. Mason, Paul D. Atkinson, Edward J. Evans, Robert J. C. Gilbert, David I. Stuart, Janet A. Fennelly, A. Neil Barclay, Simm J. Davis, and Marion H. Brown: Signaling Lymphocytic Activation Molecule (CDw150) Is Homophilic but Self-associates with Very Low Affinity
J. Biol. Chem. 2000 275: 28100-28109. [Abstract] [Full Text] [PDF]

Elena G. Yarmola, Thayumanasamy Somasundaram, Todd A. Boring, Ilan Spector, and Michael R. Bubb: Actin-Latrunculin A Structure and Function. DIFFERENTIAL MODULATION OF ACTIN-BINDING PROTEIN FUNCTION BY LATRUNCULIN A
J. Biol. Chem. 2000 275: 28120-28127. [Abstract] [Full Text] [PDF]

Yuji Tsuji, Yoshimi Shimada, Tomoko Takeshita, Naoko Kajimura, Sayuri Nomura, Naohiro Sekiyama, Jun Otomo, Jiro Usukura, Shigetada Nakanishi, and Hisato Jingami: Cryptic Dimer Interface and Domain Organization of the Extracellular Region of Metabotropic Glutamate Receptor Subtype 1
J. Biol. Chem. 2000 275: 28144-28151. [Abstract] [Full Text] [PDF]

Enzyme Catalysis and Regulation:

Michael G. Thomas, Thomas B. Thompson, Ivan Rayment, and Jorge C. Escalante-Semerena: Analysis of the Adenosylcobinamide Kinase/Adenosylcobinamide-phosphate Guanylyltransferase (CobU) Enzyme of Salmonella typhimurium LT2. IDENTIFICATION OF RESIDUE His-46 AS THE SITE OF GUANYLYLATION
J. Biol. Chem. 2000 275: 27576-27586. [Abstract] [Full Text] [PDF]

Larry S. Tobacman and Carol A. Butters: A New Model of Cooperative Myosin-Thin Filament Binding
J. Biol. Chem. 2000 275: 27587-27593. [Abstract] [Full Text] [PDF]

Bijan Bambai and Richard J. Kulmacz: Prostaglandin H Synthase. EFFECTS OF PEROXIDASE COSUBSTRATES ON CYCLOOXYGENASE VELOCITY
J. Biol. Chem. 2000 275: 27608-27614. [Abstract] [Full Text] [PDF]

Bartholomew A. Pederson, Christine Cheng, Wayne A. Wilson, and Peter J. Roach: Regulation of Glycogen Synthase. IDENTIFICATION OF RESIDUES INVOLVED IN REGULATION BY THE ALLOSTERIC LIGAND GLUCOSE-6-P AND BY PHOSPHORYLATION
J. Biol. Chem. 2000 275: 27753-27761. [Abstract] [Full Text] [PDF]

Sama Tamrakar and John W. Ludlow: The Carboxyl-terminal Region of the Retinoblastoma Protein Binds Non-competitively to Protein Phosphatase Type 1 $alpha$ and Inhibits Catalytic Activity
J. Biol. Chem. 2000 275: 27784-27789. [Abstract] [Full Text] [PDF]

Thomas J. O'Farrell and Tayebeh Pourmotabbed: Identification of Structural Elements Important for Matrix Metalloproteinase Type V Collagenolytic Activity as Revealed by Chimeric Enzymes. ROLE OF FIBRONECTIN-LIKE DOMAIN AND ACTIVE SITE OF GELATINASE B
J. Biol. Chem. 2000 275: 27964-27972. [Abstract] [Full Text] [PDF]

Merritt K. Taylor and Michael D. Uhler: The Amino-terminal Cyclic Nucleotide Binding Site of the Type II cGMP-dependent Protein Kinase Is Essential for Full Cyclic Nucleotide-dependent Activation
J. Biol. Chem. 2000 275: 28053-28062. [Abstract] [Full Text] [PDF]

Mikyung Yun, Cheon-Gil Park, Ji-Yeon Kim, Charles O. Rock, Suzanne Jackowski, and Hee-Won Park: Structural Basis for the Feedback Regulation of Escherichia coli Pantothenate Kinase by Coenzyme A
J. Biol. Chem. 2000 275: 28093-28099. [Abstract] [Full Text] [PDF]

Geeng-Fu Jang, Joshua K. McBee, Andrei M. Alekseev, Françoise Haeseleer, and Krzysztof Palczewski: Stereoisomeric Specificity of the Retinoid Cycle in the Vertebrate Retina
J. Biol. Chem. 2000 275: 28128-28138. [Abstract] [Full Text] [PDF]

Keiichi Komeima, Yuji Hayashi, Yasuhito Naito, and Yasuo Watanabe: Inhibition of Neuronal Nitric-oxide Synthase by Calcium/ Calmodulin-dependent Protein Kinase II $alpha$ through Ser⁸⁴⁷ Phosphorylation in NG108-15 Neuronal Cells
J. Biol. Chem. 2000 275: 28139-28143. [Abstract] [Full Text] [PDF]

Fernando Rodrigues-Lima, Amanda C. Fensome, Michelle Josephs, Joe Evans, Robert J. Veldman, and Matilda Katan: Structural Requirements for Catalysis and Membrane Targeting of Mammalian Enzymes with Neutral Sphingomyelinase and Lysophospholipid Phospholipase C Activities. ANALYSIS BY CHEMICAL MODIFICATION AND SITE-DIRECTED MUTAGENESIS
J. Biol. Chem. 2000 275: 28316-28325. [Abstract] [Full Text] [PDF]

Metabolism and Bioenergetics:

Francis Duffieux, Joris Van Roy, Paul A. M. Michels, and Fred R. Opperdoes: Molecular Characterization of the First Two Enzymes of the Pentose-phosphate Pathway of Trypanosoma brucei. GLUCOSE-6-PHOSPHATE DEHYDROGENASE AND 6-PHOSPHOGLUCONOLACTONASE
J. Biol. Chem. 2000 275: 27559-27565. [Abstract] [Full Text] [PDF]

Wolfram S. Kunz, Alexei Kudin, Stefan Vielhaber, Christian E. Elger, Giuseppe Attardi, and Gaetano Villani: Flux Control of Cytochrome c Oxidase in Human Skeletal Muscle
J. Biol. Chem. 2000 275: 27741-27745. [Abstract] [Full Text] [PDF]

Glycobiology and Extracellular Matrices:

Thierry Fontaine, Catherine Simenel, Guy Dubreucq, Olivier Adam, Muriel Delepierre, Jérome Lemoine, Constantin E. Vorgias, Michel Diaquin, and Jean-Paul Latgé: Molecular Organization of the Alkali-insoluble Fraction of Aspergillus fumigatus Cell Wall
J. Biol. Chem. 2000 275: 27594-27607. [Abstract] [Full Text] [PDF]

Vinata B. Lokeshwar and Marie G. Selzer: Differences in Hyaluronic Acid-mediated Functions and Signaling in Arterial, Microvessel, and Vein-derived Human Endothelial Cells
J. Biol. Chem. 2000 275: 27641-27649. [Abstract] [Full Text] [PDF]

Guido D. Pollevick, Javier M. Di Noia, Maria L. Salto, Carlos Lima, M. Susana Leguizamón, Rosa M. de Lederkremer, and Alberto C. C. Frasch: Trypanosoma cruzi Surface Mucins with Exposed Variant Epitopes
J. Biol. Chem. 2000 275: 27671-27680. [Abstract] [Full Text] [PDF]

Ge Wei, Xiaomei Bai, Mary M. G. Gabb, Karen J. Bame, Thomas I. Koshy, Patricia G. Spear, and Jeffrey D. Esko: Location of the Glucuronosyltransferase Domain in the Heparan Sulfate Copolymerase EXT1 by Analysis of Chinese Hamster Ovary Cell Mutants
J. Biol. Chem. 2000 275: 27733-27740. [Abstract] [Full Text] [PDF]

Sergio R. Filipe, Mariana G. Pinho, and Alexander Tomasz: Characterization of the murMN Operon Involved in the Synthesis of Branched Peptidoglycan Peptides in Streptococcus pneumoniae
J. Biol. Chem. 2000 275: 27768-27774. [Abstract] [Full Text] [PDF]

Michael A. Chernousov, Katrina Rothblum, William A. Tyler, Richard C. Stahl, and David J. Carey: Schwann Cells Synthesize Type V Collagen That Contains a Novel $alpha$ 4 Chain. MOLECULAR CLONING, BIOCHEMICAL CHARACTERIZATION, AND HIGH AFFINITY HEPARIN BINDING OF $alpha$ 4(V) COLLAGEN
J. Biol. Chem. 2000 275: 28208-28215. [Abstract] [Full Text] [PDF]

Mohamed Ouzzine, Sandrine Gulberti, Patrick Netter, Jacques Magdalou, and Sylvie Fournel-Gigleux: Structure/Function of the Human Gal $beta$ 1,3-glucuronosyltransferase. DIMERIZATION AND FUNCTIONAL ACTIVITY ARE MEDIATED BY TWO CRUCIAL CYSTEINE RESIDUES
J. Biol. Chem. 2000 275: 28254-28260. [Abstract] [Full Text] [PDF]

Lipids and Lipoproteins:

Mark Ramsdale and Patricia L. Lakin-Thomas: sn-1,2-Diacylglycerol Levels in the Fungus Neurospora crassa Display Circadian Rhythmicity
J. Biol. Chem. 2000 275: 27541-27550. [Abstract] [Full Text] [PDF]

Andrew J. Brown, Gerald F. Watts, John R. Burnett, Roger T. Dean, and Wendy Jessup: Sterol 27-Hydroxylase Acts on 7-Ketocholesterol in Human Atherosclerotic Lesions and Macrophages in Culture
J. Biol. Chem. 2000 275: 27627-27633. [Abstract] [Full Text] [PDF]

Nanette L. S. Que, Shanhua Lin, Robert J. Cotter, and Christian R. H. Raetz: Purification and Mass Spectrometry of Six Lipid A Species from the Bacterial Endosymbiont Rhizobium etli. DEMONSTRATION OF A CONSERVED DISTAL UNIT AND A VARIABLE PROXIMAL PORTION
J. Biol. Chem. 2000 275: 28006-28016. [Abstract] [Full Text] [PDF]

Nanette L. S. Que, Anthony A. Ribeiro, and Christian R. H. Raetz: Two-dimensional NMR Spectroscopy and Structures of Six Lipid A Species from Rhizobium etli CE3. DETECTION OF AN ACYLOXYACYL RESIDUE IN EACH COMPONENT AND ORIGIN OF THE AMINOGLUCONATE MOIETY
J. Biol. Chem. 2000 275: 28017-28027. [Abstract] [Full Text] [PDF] Supplemental Data

Catherine C. Y. Chang, Naomi Sakashita, Kim Ornvold, Oneil Lee, Ellen T. Chang, Ruhong Dong, Song Lin, Chi-Yu Gregory Lee, Stephen C. Strom, Randeep Kashyap, John J. Fung, Robert V. Farese, Jr., Jean-François Patoiseau, André Delhon, and Ta Yuan Chang: Immunological Quantitation and Localization of ACAT-1 and ACAT-2 in Human Liver and Small Intestine
J. Biol. Chem. 2000 275: 28083-28092. [Abstract] [Full Text] [PDF]

Emma J. Cheesman, Rebecca J. Sharp, Constance H. Zlot, Catherine Y.-Y. Liu, Stacy Taylor, Santica M. Marcovina, Stephen G. Young, and Sally P. A. McCormick: An Analysis of the Interaction between Mouse Apolipoprotein B100 and Apolipoprotein(a)
J. Biol. Chem. 2000 275: 28195-28200. [Abstract] [Full Text] [PDF]

Keum-Hwa Choi, Laurent Kremer, Gurdyal S. Besra, and Charles O. Rock: Identification and Substrate Specificity of $beta$ -Ketoacyl (Acyl Carrier Protein) Synthase III (mtFabH) from Mycobacterium tuberculosis
J. Biol. Chem. 2000 275: 28201-28207. [Abstract] [Full Text] [PDF]

Alain R. Baulard, Joanna C. Betts, Jean Engohang-Ndong, Selwyn Quan, Ruth A. McAdam, Patrick J. Brennan, Camille Locht, and Gurdyal S. Besra: Activation of the Pro-drug Ethionamide Is Regulated in Mycobacteria
J. Biol. Chem. 2000 275: 28326-28331. [Abstract] [Full Text] [PDF]

Membrane Transport Structure Function and Biogenesis:

Ronald A. Li, Irene L. Ennis, Patricio Vélez, Gordon F. Tomaselli, and Eduardo Marbán: Novel Structural Determinants of µ-Conotoxin (GIIIB) Block in Rat Skeletal Muscle (µ1) Na⁺ Channels
J. Biol. Chem. 2000 275: 27551-27558. [Abstract] [Full Text] [PDF]

György Lonart and Thomas C. Südhof: Assembly of SNARE Core Complexes Prior to Neurotransmitter Release Sets the Readily Releasable Pool of Synaptic Vesicles
J. Biol. Chem. 2000 275: 27703-27707. [Abstract] [Full Text] [PDF]

Nancy A. Benkusky, Daniel J. Fergus, Theresa M. Zucchero, and Sarah K. England: Regulation of the Ca²⁺-sensitive Domains of the Maxi-K Channel in the Mouse Myometrium during Gestation
J. Biol. Chem. 2000 275: 27712-27719. [Abstract] [Full Text] [PDF]

Martijn M. VanDuijn, Karmi Tijssen, John VanSteveninck, Peter J. A. Van den Broek, and Jolanda Van der Zee: Erythrocytes Reduce Extracellular Ascorbate Free Radicals Using Intracellular Ascorbate as an Electron Donor
J. Biol. Chem. 2000 275: 27720-27725. [Abstract] [Full Text] [PDF]

Weihong Liu, Daniel P. Schachtman, and Wei Zhang: Partial Deletion of a Loop Region in the High Affinity K⁺ Transporter HKT1 Changes Ionic Permeability Leading to Increased Salt Tolerance
J. Biol. Chem. 2000 275: 27924-27932. [Abstract] [Full Text] [PDF]

Hong-Long Ji, Michael L. Chalfant, Biljana Jovov, Jason P. Lockhart, Suzanne B. Parker, Catherine M. Fuller, Bruce A. Stanton, and Dale J. Benos: The Cytosolic Termini of the $beta$ - and $gamma$ -ENaC Subunits Are Involved in the Functional Interactions between Cystic Fibrosis Transmembrane Conductance Regulator and Epithelial Sodium Channel
J. Biol. Chem. 2000 275: 27947-27956. [Abstract] [Full Text] [PDF]

Ji-Bin Peng, Xing-Zhen Chen, Urs V. Berger, Peter M. Vassilev, Edward M. Brown, and Matthias A. Hediger: A Rat Kidney-specific Calcium Transporter in the Distal Nephron
J. Biol. Chem. 2000 275: 28186-28194. [Abstract] [Full Text] [PDF]

Steven C. Rumsey, Rushad Daruwala, Hadi Al-Hasani, Mary Jane Zarnowski, Ian A. Simpson, and Mark Levine: Dehydroascorbic Acid Transport by GLUT4 in Xenopus Oocytes and Isolated Rat Adipocytes
J. Biol. Chem. 2000 275: 28246-28253. [Abstract] [Full Text] [PDF]

Mechanisms Of Signal Transduction:

Miroslav Cik, Stefan Masure, Anne S. J. Lesage, Ilse Van der Linden, Paul Van Gompel, Menelas N. Pangalos, Robert D. Gordon, and Josée E. Leysen: Binding of GDNF and Neurturin to Human GDNF Family Receptor $alpha$ 1 and 2. INFLUENCE OF cRET AND COOPERATIVE INTERACTIONS
J. Biol. Chem. 2000 275: 27505-27512. [Abstract] [Full Text] [PDF]

James Xu, Lana M. Love, Indrapal Singh, Qiu-Xia Zhang, Jay Dewald, De-An Wang, David J. Fischer, Gabor Tigyi, Luc G. Berthiaume, David W. Waggoner, and David N. Brindley: Lipid Phosphate Phosphatase-1 and Ca²⁺ Control Lysophosphatidate Signaling through EDG-2 Receptors
J. Biol. Chem. 2000 275: 27520-27530. [Abstract] [Full Text] [PDF]

Blaithin McMahon, Catherine Stenson, Fiona McPhillips, Aine Fanning, Hugh R. Brady, and Catherine Godson: Lipoxin A₄ Antagonizes the Mitogenic Effects of Leukotriene D₄ in Human Renal Mesangial Cells. DIFFERENTIAL ACTIVATION OF MAP KINASES THROUGH DISTINCT RECEPTORS
J. Biol. Chem. 2000 275: 27566-27575. [Abstract] [Full Text] [PDF]

Poda Suresh Babu, Hanumanthappa Krishnamurthy, P. Jorge Chedrese, and M. Ram Sairam: Activation of Extracellular-regulated Kinase Pathways in Ovarian Granulosa Cells by the Novel Growth Factor Type 1 Follicle-stimulating Hormone Receptor. ROLE IN HORMONE SIGNALING AND CELL PROLIFERATION
J. Biol. Chem. 2000 275: 27615-27626. [Abstract] [Full Text] [PDF]

Shahab Uddin, Fatima Lekmine, Niti Sharma, Beata Majchrzak, Ingrid Mayer, Peter R. Young, Gary M. Bokoch, Eleanor N. Fish, and Leonidas C. Platanias: The Rac1/p38 Mitogen-activated Protein Kinase Pathway Is Required for Interferon $alpha$ -dependent Transcriptional Activation but Not Serine Phosphorylation of Stat Proteins
J. Biol. Chem. 2000 275: 27634-27640. [Abstract] [Full Text] [PDF]

Geraldine A. Finlay, Victor J. Thannickal, Barry L. Fanburg, and K. Eric Paulson: Transforming Growth Factor- $beta$ 1-induced Activation of the ERK Pathway/Activator Protein-1 in Human Lung Fibroblasts Requires the Autocrine Induction of Basic Fibroblast Growth Factor
J. Biol. Chem. 2000 275: 27650-27656. [Abstract] [Full Text] [PDF]

Christine Kroner, Kurt Eybrechts, and Jan-Willem N. Akkerman: Dual Regulation of Platelet Protein Kinase B
J. Biol. Chem. 2000 275: 27790-27798. [Abstract] [Full Text] [PDF]

Birgit Lintschinger, Monika Balzer-Geldsetzer, Tyagarajan Baskaran, Wolfgang F. Graier, Christoph Romanin, Michael X. Zhu, and Klaus Groschner: Coassembly of Trp1 and Trp3 Proteins Generates Diacylglycerol- and Ca²⁺-sensitive Cation Channels
J. Biol. Chem. 2000 275: 27799-27805. [Abstract] [Full Text] [PDF]

Naohiro Inohara, Takeyoshi Koseki, Jingmei Lin, Luis del Peso, Peter C. Lucas, Felicia F. Chen, Yasunori Ogura, and Gabriel Núñez: An Induced Proximity Model for NF- $kappa$ B Activation in the Nod1/RICK and RIP Signaling Pathways
J. Biol. Chem. 2000 275: 27823-27831. [Abstract] [Full Text] [PDF]

Michael Haas, Amir Askari, and Zijian Xie: Involvement of Src and Epidermal Growth Factor Receptor in the Signal-transducing Function of Na⁺/K⁺-ATPase
J. Biol. Chem. 2000 275: 27832-27837. [Abstract] [Full Text] [PDF]

Jiang Liu, Jiang Tian, Michael Haas, Joseph I. Shapiro, Amir Askari, and Zijian Xie: Ouabain Interaction with Cardiac Na⁺/K⁺-ATPase Initiates Signal Cascades Independent of Changes in Intracellular Na⁺ and Ca²⁺ Concentrations
J. Biol. Chem. 2000 275: 27838-27844. [Abstract] [Full Text] [PDF]

Dharminder Chauhan, Pramod Pandey, Teru Hideshima, Steven Treon, Noopur Raje, Faith E. Davies, Yoshi Shima, Yu-Tzu Tai, Steven Rosen, Shalom Avraham, Surender Kharbanda, and Kenneth C. Anderson: SHP2 Mediates the Protective Effect of Interleukin-6 against Dexamethasone-induced Apoptosis in Multiple Myeloma Cells
J. Biol. Chem. 2000 275: 27845-27850. [Abstract] [Full Text] [PDF]

A. Brent Carter and Gary W. Hunninghake: A Constitutive Active MEK $right-arrow$ ERK Pathway Negatively Regulates NF- $kappa$ B-dependent Gene Expression by Modulating TATA-binding Protein Phosphorylation
J. Biol. Chem. 2000 275: 27858-27864. [Abstract] [Full Text] [PDF]

Mir Ahamed Hossain, Christopher M. L. Bouton, Jonathan Pevsner, and John Laterra: Induction of Vascular Endothelial Growth Factor in Human Astrocytes by Lead. INVOLVEMENT OF A PROTEIN KINASE C/ACTIVATOR PROTEIN-1 COMPLEX-DEPENDENT AND HYPOXIA-INDUCIBLE FACTOR 1-INDEPENDENT SIGNALING PATHWAY
J. Biol. Chem. 2000 275: 27874-27882. [Abstract] [Full Text] [PDF]

Panayiotis O. Vacratsis and Kathleen A. Gallo: Zipper-mediated Oligomerization of the Mixed Lineage Kinase SPRK/MLK-3 Is Not Required for Its Activation by the GTPase cdc 42 but Is Necessary for Its Activation of the JNK Pathway. MONOMERIC SPRK L410P DOES NOT CATALYZE THE ACTIVATING PHOSPHORYLATION OF Thr²⁵⁸ OF MURINE MITOGEN-ACTIVATED PROTEIN KINASE KINASE 4
J. Biol. Chem. 2000 275: 27893-27900. [Abstract] [Full Text] [PDF]

Richard L. Cai, Yan Yan-Neale, Maria A. Cueto, Hong Xu, and Dalia Cohen: HDAC1, a Histone Deacetylase, Forms a Complex with Hus1 and Rad9, Two G₂/M Checkpoint Rad Proteins
J. Biol. Chem. 2000 275: 27909-27916. [Abstract] [Full Text] [PDF]

Lucile Gouédard, Ye-Guang Chen, Laurie Thevenet, Chrystèle Racine, Sandrine Borie, Isabelle Lamarre, Nathalie Josso, Joan Massagué, and Nathalie di Clemente: Engagement of Bone Morphogenetic Protein Type IB Receptor and Smad1 Signaling by Anti-Müllerian Hormone and Its Type II Receptor
J. Biol. Chem. 2000 275: 27973-27978. [Abstract] [Full Text] [PDF]

Federico Kalinec, Ming Zhang, Raul Urrutia, and Gilda Kalinec: Rho GTPases Mediate the Regulation of Cochlear Outer Hair Cell Motility by Acetylcholine
J. Biol. Chem. 2000 275: 28000-28005. [Abstract] [Full Text] [PDF]

Elaine Huston, Matthew Beard, Fraser McCallum, Nigel J. Pyne, Peter Vandenabeele, Grant Scotland, and Miles D. Houslay: The cAMP-specific Phosphodiesterase PDE4A5 Is Cleaved Downstream of Its SH3 Interaction Domain by Caspase-3. CONSEQUENCES FOR ALTERED INTRACELLULAR DISTRIBUTION
J. Biol. Chem. 2000 275: 28063-28074. [Abstract] [Full Text] [PDF]

Thomas Benzing, Michael B. Yaffe, Thierry Arnould, Lorenz Sellin, Bernhard Schermer, Birgit Schilling, Rainer Schreiber, Karl Kunzelmann, German G. Leparc, Emily Kim, and Gerd Walz: 14-3-3 Interacts with Regulator of G Protein Signaling Proteins and Modulates Their Activity
J. Biol. Chem. 2000 275: 28167-28172. [Abstract] [Full Text] [PDF]

Ji H. Paik, Jeong H. Ju, Joo Y. Lee, Mary D. Boudreau, and Daniel H. Hwang: Two Opposing Effects of Non-steroidal Anti-inflammatory Drugs on the Expression of the Inducible Cyclooxygenase. MEDIATION THROUGH DIFFERENT SIGNALING PATHWAYS
J. Biol. Chem. 2000 275: 28173-28179. [Abstract] [Full Text] [PDF]

Nobuhiro Tanuma, Koji Nakamura, Hiroshi Shima, and Kunimi Kikuchi: Protein-tyrosine Phosphatase PTP $epsilon$ C Inhibits Jak-STAT Signaling and Differentiation Induced by Interleukin-6 and Leukemia Inhibitory Factor in M1 Leukemia Cells
J. Biol. Chem. 2000 275: 28216-28221. [Abstract] [Full Text] [PDF]

Mary R. Stofega, Lawrence S. Argetsinger, Hongyang Wang, Axel Ullrich, and Christin Carter-Su: Negative Regulation of Growth Hormone Receptor/JAK2 Signaling by Signal Regulatory Protein $alpha$
J. Biol. Chem. 2000 275: 28222-28229. [Abstract] [Full Text] [PDF]

Gyles E. Cozier, Peter J. Lockyer, Jon S. Reynolds, Sabine Kupzig, Joanna R. Bottomley, Tom H. Millard, George Banting, and Peter J. Cullen: GAP1^IP4BP Contains a Novel Group I Pleckstrin Homology Domain That Directs Constitutive Plasma Membrane Association
J. Biol. Chem. 2000 275: 28261-28268. [Abstract] [Full Text] [PDF]

Daniel Vial, Hitoshi Okazaki, and Reuben P. Siraganian: The NH₂-terminal Region of Focal Adhesion Kinase Reconstitutes High Affinity IgE Receptor-induced Secretion in Mast Cells
J. Biol. Chem. 2000 275: 28269-28275. [Abstract] [Full Text] [PDF]

Yu-Jui Yvonne Wan, Yan Cai, William Lungo, Paul Fu, Joseph Locker, Samuel French, and Henry M. Sucov: Peroxisome Proliferator-activated Receptor $alpha$ -mediated Pathways Are Altered in Hepatocyte-specific Retinoid X Receptor $alpha$ -deficient Mice
J. Biol. Chem. 2000 275: 28285-28290. [Abstract] [Full Text] [PDF]

Molecular Basis Of Cell and Developmental Biology:

Gregory Jefford and Ronald R. Dubreuil: Receptor Clustering Drives Polarized Assembly of Ankyrin
J. Biol. Chem. 2000 275: 27726-27732. [Abstract] [Full Text] [PDF]

Naoya Sawamura, Maho Morishima-Kawashima, Hatsue Waki, Kimio Kobayashi, Takashi Kuramochi, Matthew P. Frosch, Kai Ding, Mamoru Ito, Tae-Wan Kim, Rudolph E. Tanzi, Fumitaka Oyama, Takeshi Tabira, Susumu Ando, and Yasuo Ihara: Mutant Presenilin 2 Transgenic Mice. A LARGE INCREASE IN THE LEVELS OF A $beta$ 42 IS PRESUMABLY ASSOCIATED WITH THE LOW DENSITY MEMBRANE DOMAIN THAT CONTAINS DECREASED LEVELS OF GLYCEROPHOSPHOLIPIDS AND SPHINGOMYELIN
J. Biol. Chem. 2000 275: 27901-27908. [Abstract] [Full Text] [PDF]

Karen Kustedjo, Michael H. Bracey, and Benjamin F. Cravatt: Torsin A and Its Torsion Dystonia-associated Mutant Forms Are Lumenal Glycoproteins That Exhibit Distinct Subcellular Localizations
J. Biol. Chem. 2000 275: 27933-27939. [Abstract] [Full Text] [PDF]

Klaus Ebnet, Christian U. Schulz, Maria-Katharina Meyer zu Brickwedde, Gunther G. Pendl, and Dietmar Vestweber: Junctional Adhesion Molecule Interacts with the PDZ Domain-containing Proteins AF-6 and ZO-1
J. Biol. Chem. 2000 275: 27979-27988. [Abstract] [Full Text] [PDF]

Mitsunori Fukuda and Katsuhiko Mikoshiba: Distinct Self-oligomerization Activities of Synaptotagmin Family. UNIQUE CALCIUM-DEPENDENT OLIGOMERIZATION PROPERTIES OF SYNAPTOTAGMIN VII
J. Biol. Chem. 2000 275: 28180-28185. [Abstract] [Full Text] [PDF]

Brendon Price, Clive Dennison, Harald Tschesche, and Edith Elliott: Neutrophil Tissue Inhibitor of Matrix Metalloproteinases-1 Occurs in Novel Vesicles That Do Not Fuse with the Phagosome
J. Biol. Chem. 2000 275: 28308-28315. [Abstract] [Full Text] [PDF]

Tao Zhao, Thomas Heyduk, C. David Allis, and Joel C. Eissenberg: Heterochromatin Protein 1 Binds to Nucleosomes and DNA in Vitro
J. Biol. Chem. 2000 275: 28332-28338. [Abstract] [Full Text] [PDF]

Additions and Corrections:

Leigh A. Knodler, Robert Noiva, Kapil Mehta, J. Michael McCaffery, Stephen B. Aley, Staffan G. Svärd, Todd G. Nystul, David S. Reiner, Jeffrey D. Silberman, and Frances D. Gillin: Novel protein-disulfide isomerases from the early-diverging protist Giardia lamblia.
J. Biol. Chem. 2000 275: 28339. [Full Text] [PDF]

Robert H. Weiss, Adriane Joo, and Collette Randour: p21^Waf1/Cip1 is an assembly factor required for platelet-derived growth factor-induced vascular smooth muscle cell proliferation.
J. Biol. Chem. 2000 275: 28340. [Full Text] [PDF]