Minireviews:

Scott L. Friedman

Molecular Regulation of Hepatic Fibrosis, an Integrated Cellular Response to Tissue Injury
J. Biol. Chem. 2000 275: 2247-2250. [Full Text] [PDF]  

Accelerated Publications:

Kiyoshi Kawasaki, Sachiko Akashi, Rintaro Shimazu, Takashi Yoshida, Kensuke Miyake, and Masahiro Nishijima

Mouse Toll-like Receptor 4·MD-2 Complex Mediates Lipopolysaccharide-mimetic Signal Transduction by Taxol
J. Biol. Chem. 2000 275: 2251-2254. [Abstract] [Full Text] [PDF]  

Hazem Hallak, Andrea E. M. Seiler, Jaime S. Green, Brian N. Ross, and Raphael Rubin

Association of Heterotrimeric G_i with the Insulin-like Growth Factor-I Receptor. RELEASE OF G SUBUNITS UPON RECEPTOR ACTIVATION
J. Biol. Chem. 2000 275: 2255-2258. [Abstract] [Full Text] [PDF]  

Carbohydrates, Lipids, and Other Natural Products:

Hidenao Toyoda, Akiko Kinoshita-Toyoda, and Scott B. Selleck

Structural Analysis of Glycosaminoglycans in Drosophila and Caenorhabditis elegans and Demonstration That tout-velu, a Drosophila Gene Related to EXT Tumor Suppressors, Affects Heparan Sulfate in Vivo
J. Biol. Chem. 2000 275: 2269-2275. [Abstract] [Full Text] [PDF]  

Marjorie F. Oleksiak, Shu Wu, Carol Parker, Sibel I. Karchner, John J. Stegeman, and Darryl C. Zeldin

Identification, Functional Characterization, and Regulation of a New Cytochrome P450 Subfamily, the CYP2Ns
J. Biol. Chem. 2000 275: 2312-2321. [Abstract] [Full Text] [PDF]  

Matthias Eckhardt, Holger Barth, Dagmar Blöcker, and Klaus Aktories

Binding of Clostridium botulinum C2 Toxin to Asparagine-linked Complex and Hybrid Carbohydrates
J. Biol. Chem. 2000 275: 2328-2334. [Abstract] [Full Text] [PDF]  

Stéphane Sidobre, Jérome Nigou, Germain Puzo, and Michel Rivière

Lipoglycans Are Putative Ligands for the Human Pulmonary Surfactant Protein A Attachment to Mycobacteria. CRITICAL ROLE OF THE LIPIDS FOR LECTIN-CARBOHYDRATE RECOGNITION
J. Biol. Chem. 2000 275: 2415-2422. [Abstract] [Full Text] [PDF]  

Koteppa Pari, C. Sivakama Sundari, Sushil Chandani, and Dorairajan Balasubramanian

-Carbolines That Accumulate in Human Tissues May Serve a Protective Role against Oxidative Stress
J. Biol. Chem. 2000 275: 2455-2462. [Abstract] [Full Text] [PDF]  

Anne Burke, John A. Lawson, Emma A. Meagher, Joshua Rokach, and Garret A. FitzGerald

Specific Analysis in Plasma and Urine of 2,3-Dinor-5,6-dihydro-isoprostane F₂-III, a Metabolite of Isoprostane F₂-III and an Oxidation Product of -Linolenic Acid
J. Biol. Chem. 2000 275: 2499-2504. [Abstract] [Full Text] [PDF]  

Hiroko Habuchi, Masayuki Tanaka, Osami Habuchi, Keiichi Yoshida, Hiroaki Suzuki, Kazuhiko Ban, and Koji Kimata

The Occurrence of Three Isoforms of Heparan Sulfate 6-O-Sulfotransferase Having Different Specificities for Hexuronic Acid Adjacent to the Targeted N-Sulfoglucosamine
J. Biol. Chem. 2000 275: 2859-2868. [Abstract] [Full Text] [PDF]  

Cell Biology and Metabolism:

Efrat Landau, Regine Tirosh, Arie' Pinson, Shmuel Banai, Sharona Even-Ram, Miriam Maoz, Shulamit Katzav, and Rachel Bar-Shavit

Protection of Thrombin Receptor Expression under Hypoxia
J. Biol. Chem. 2000 275: 2281-2287. [Abstract] [Full Text] [PDF]  

Chi Lin, Johan Widjaja, and Suresh K. Joseph

The Interaction of Calmodulin with Alternatively Spliced Isoforms of the Type-I Inositol Trisphosphate Receptor
J. Biol. Chem. 2000 275: 2305-2311. [Abstract] [Full Text] [PDF]  

Rong Yu, Sandhya Mandlekar, Wei Lei, William E. Fahl, Tse-Hua Tan, and A.-N. Tony Kong

p38 Mitogen-activated Protein Kinase Negatively Regulates the Induction of Phase II Drug-metabolizing Enzymes That Detoxify Carcinogens
J. Biol. Chem. 2000 275: 2322-2327. [Abstract] [Full Text] [PDF]  

Julien Cau, Sandrine Faure, Suzanne Vigneron, Jean Claude Labbé, Claude Delsert, and Nathalie Morin

Regulation of Xenopus p21-activated Kinase (X-PAK2) by Cdc42 and Maturation-promoting Factor Controls Xenopus Oocyte Maturation
J. Biol. Chem. 2000 275: 2367-2375. [Abstract] [Full Text] [PDF]  

Soichi Noguchi, Suree Jianmongkol, Andrew T. Bender, Yasuhiko Kamada, Damon R. Demady, and Yoichi Osawa

Guanabenz-mediated Inactivation and Enhanced Proteolytic Degradation of Neuronal Nitric-oxide Synthase
J. Biol. Chem. 2000 275: 2376-2380. [Abstract] [Full Text] [PDF]  

Angela Glading, Philip Chang, Douglas A. Lauffenburger, and Alan Wells

Epidermal Growth Factor Receptor Activation of Calpain Is Required for Fibroblast Motility and Occurs via an ERK/MAP Kinase Signaling Pathway
J. Biol. Chem. 2000 275: 2390-2398. [Abstract] [Full Text] [PDF]  

Liwu Li, Mats Ljungman, and Jack E. Dixon

The Human Cdc14 Phosphatases Interact with and Dephosphorylate the Tumor Suppressor Protein p53
J. Biol. Chem. 2000 275: 2410-2414. [Abstract] [Full Text] [PDF]  

Zhi-Jie Cheng, Jian Zhao, Yue Sun, Wei Hu, Ya-Lan Wu, Bo Cen, Guo-Xiang Wu, and Gang Pei

-Arrestin Differentially Regulates the Chemokine Receptor CXCR4-mediated Signaling and Receptor Internalization, and This Implicates Multiple Interaction Sites between -Arrestin and CXCR4
J. Biol. Chem. 2000 275: 2479-2485. [Abstract] [Full Text] [PDF]  

Heidemarie I. Krieger-Brauer, Pankaj K. Medda, Brigitte Sattel, and Horst Kather

Inhibitory Effect of Isoproterenol on NADPH-dependent H₂O₂ Generation in Human Adipocyte Plasma Membranes Is Mediated by -Subunits Derived from G_s
J. Biol. Chem. 2000 275: 2486-2490. [Abstract] [Full Text] [PDF]  

Tatyana A. Prokhorova and J. Julian Blow

Sequential MCM/P1 Subcomplex Assembly Is Required to Form a Heterohexamer with Replication Licensing Activity
J. Biol. Chem. 2000 275: 2491-2498. [Abstract] [Full Text] [PDF]  

Daniel Ritz, Hiten Patel, Bernard Doan, Ming Zheng, Fredrik Åslund, Gisela Storz, and Jon Beckwith

Thioredoxin 2 Is Involved in the Oxidative Stress Response in Escherichia coli
J. Biol. Chem. 2000 275: 2505-2512. [Abstract] [Full Text] [PDF]  

Tian-Hua Zhou, Kun Ling, Jun Guo, Hui Zhou, Ya-Lan Wu, Qing Jing, Lan Ma, and Gang Pei

Identification of a Human Brain-specific Isoform of Mammalian STE20-like Kinase 3 That Is Regulated by cAMP-dependent Protein Kinase
J. Biol. Chem. 2000 275: 2513-2519. [Abstract] [Full Text] [PDF]  

Hee-Sae Park, Eun Park, Mi-Sung Kim, Kwangseog Ahn, Ick Young Kim, and Eui-Ju Choi

Selenite Inhibits the c-Jun N-terminal Kinase/Stress-activated Protein Kinase (JNK/SAPK) through a Thiol Redox Mechanism
J. Biol. Chem. 2000 275: 2527-2531. [Abstract] [Full Text] [PDF]  

Hajir Dadgostar and Genhong Cheng

Membrane Localization of TRAF 3 Enables JNK Activation
J. Biol. Chem. 2000 275: 2539-2544. [Abstract] [Full Text] [PDF]  

Leslie A. Goldstein and Wen-Tien Chen

Identification of an Alternatively Spliced Seprase mRNA That Encodes a Novel Intracellular Isoform
J. Biol. Chem. 2000 275: 2554-2559. [Abstract] [Full Text] [PDF]  

Luis A. Garza and Morris J. Birnbaum

Insulin-responsive Aminopeptidase Trafficking in 3T3-L1 Adipocytes
J. Biol. Chem. 2000 275: 2560-2567. [Abstract] [Full Text] [PDF]  

Daniel M. Skovronsky, D. Blaine Moore, Marcos E. Milla, Robert W. Doms, and Virginia M.-Y. Lee

Protein Kinase C-dependent -Secretase Competes with -Secretase for Cleavage of Amyloid- Precursor Protein in the Trans-Golgi Network
J. Biol. Chem. 2000 275: 2568-2575. [Abstract] [Full Text] [PDF]  

Ignacio Munoz-Sanjuan, Philip M. Smallwood, and Jeremy Nathans

Isoform Diversity among Fibroblast Growth Factor Homologous Factors Is Generated by Alternative Promoter Usage and Differential Splicing
J. Biol. Chem. 2000 275: 2589-2597. [Abstract] [Full Text] [PDF]  

Kyle E. Miller and Michael P. Sheetz

Characterization of Myosin V Binding to Brain Vesicles
J. Biol. Chem. 2000 275: 2598-2606. [Abstract] [Full Text] [PDF]  

Shizuya Saika, Atsushi Shiraishi, Satoko Saika, Chia-Yang Liu, James L. Funderburgh, Candace W.-C. Kao, Richard L. Converse, and Winston W.-Y. Kao

Role of Lumican in the Corneal Epithelium during Wound Healing
J. Biol. Chem. 2000 275: 2607-2612. [Abstract] [Full Text] [PDF]  

Yasuyuki Irie, Kanato Yamagata, Yehua Gan, Kaoru Miyamoto, Eunju Do, Che-Hui Kuo, Eiichi Taira, and Naomasa Miki

Molecular Cloning and Characterization of Amida, a Novel Protein Which Interacts with a Neuron-specific Immediate Early Gene Product Arc, Contains Novel Nuclear Localization Signals, and Causes Cell Death in Cultured Cells
J. Biol. Chem. 2000 275: 2647-2653. [Abstract] [Full Text] [PDF]  

Pierrick Rochard, Anne Rodier, François Casas, Isabelle Cassar-Malek, Sophie Marchal-Victorion, Laetitia Daury, Chantal Wrutniak, and Gérard Cabello

Mitochondrial Activity Is Involved in the Regulation of Myoblast Differentiation through Myogenin Expression and Activity of Myogenic Factors
J. Biol. Chem. 2000 275: 2733-2744. [Abstract] [Full Text] [PDF]  

Joachim Saas, Karl Ziegelbauer, Arndt von Haeseler, Beate Fast, and Michael Boshart

A Developmentally Regulated Aconitase Related to Iron-regulatory Protein-1 Is Localized in the Cytoplasm and in the Mitochondrion of Trypanosoma brucei
J. Biol. Chem. 2000 275: 2745-2755. [Abstract] [Full Text] [PDF]  

Darren D. Browning, Marisa P. McShane, Caroline Marty, and Richard D. Ye

Nitric Oxide Activation of p38 Mitogen-activated Protein Kinase in 293T Fibroblasts Requires cGMP-dependent Protein Kinase
J. Biol. Chem. 2000 275: 2811-2816. [Abstract] [Full Text] [PDF]  

Tetsuya Miyamoto and Jonathan C. Fox

Autocrine Signaling through Ras Prevents Apoptosis in Vascular Smooth Muscle Cells in Vitro
J. Biol. Chem. 2000 275: 2825-2830. [Abstract] [Full Text] [PDF]  

Giovanni M. Lesa, Joachim Seemann, James Shorter, Joël Vandekerckhove, and Graham Warren

The Amino-terminal Domain of the Golgi Protein Giantin Interacts Directly with the Vesicle-tethering Protein p115
J. Biol. Chem. 2000 275: 2831-2836. [Abstract] [Full Text] [PDF]  

Albino Bonazzi, Vladimir Mastyugin, Paul A. Mieyal, Michael W. Dunn, and Michal Laniado-Schwartzman

Regulation of Cyclooxygenase-2 by Hypoxia and Peroxisome Proliferators in the Corneal Epithelium
J. Biol. Chem. 2000 275: 2837-2844. [Abstract] [Full Text] [PDF]  

Marina Shenkman, Marcelo Ehrlich, and Gerardo Z. Lederkremer

Masking of an Endoplasmic Reticulum Retention Signal by Its Presence in the Two Subunits of the Asialoglycoprotein Receptor
J. Biol. Chem. 2000 275: 2845-2851. [Abstract] [Full Text] [PDF]  

Hiroshi Suzuki, Tomoki Chiba, Toshiaki Suzuki, Takashi Fujita, Tsuneo Ikenoue, Masao Omata, Kiyoshi Furuichi, Hisataka Shikama, and Keiji Tanaka

Homodimer of Two F-box Proteins TrCP1 or TrCP2 Binds to IB for Signal-dependent Ubiquitination
J. Biol. Chem. 2000 275: 2877-2884. [Abstract] [Full Text] [PDF]  

Liangyou Rui, Stephen F. Archer, Lawrence S. Argetsinger, and Christin Carter-Su

Platelet-derived Growth Factor and Lysophosphatidic Acid Inhibit Growth Hormone Binding and Signaling via a Protein Kinase C-dependent Pathway
J. Biol. Chem. 2000 275: 2885-2892. [Abstract] [Full Text] [PDF]  

Walter G. Thomas, Hongwei Qian, Chang-Sheng Chang, and Sadashiva Karnik

Agonist-induced Phosphorylation of the Angiotensin II (AT_1A) Receptor Requires Generation of a Conformation That Is Distinct from the Inositol Phosphate-signaling State
J. Biol. Chem. 2000 275: 2893-2900. [Abstract] [Full Text] [PDF]  

Monika Bähner, Philipp Sander, Reinhard Paulsen, and Armin Huber

The Visual G Protein of Fly Photoreceptors Interacts with the PDZ Domain Assembled INAD Signaling Complex via Direct Binding of Activated G_q to Phospholipase C
J. Biol. Chem. 2000 275: 2901-2904. [Abstract] [Full Text] [PDF]  

Tomoko Hirohashi, Hiroshi Suzuki, Hajime Takikawa, and Yuichi Sugiyama

ATP-dependent Transport of Bile Salts by Rat Multidrug Resistance-associated Protein 3 (Mrp3)
J. Biol. Chem. 2000 275: 2905-2910. [Abstract] [Full Text] [PDF]  

Susan Tsujimoto and Andrew J. Bean

Distinct Protein Domains Are Responsible for the Interaction of Hrs-2 with SNAP-25. THE ROLE OF Hrs-2 IN 7 S COMPLEX FORMATION
J. Biol. Chem. 2000 275: 2938-2942. [Abstract] [Full Text] [PDF]  

Alvaro Puga, Sonya J. Barnes, Timothy P. Dalton, Ching-yi Chang, Erik S. Knudsen, and Michael A. Maier

Aromatic Hydrocarbon Receptor Interaction with the Retinoblastoma Protein Potentiates Repression of E2F-dependent Transcription and Cell Cycle Arrest
J. Biol. Chem. 2000 275: 2943-2950. [Abstract] [Full Text] [PDF]  

Jing Li, Yong-Nyun Kim, and Paul J. Bertics

Platelet-derived Growth Factor-stimulated Migration of Murine Fibroblasts Is Associated with Epidermal Growth Factor Receptor Expression and Tyrosine Phosphorylation
J. Biol. Chem. 2000 275: 2951-2958. [Abstract] [Full Text] [PDF]  

Karen Vogel, Jean-Pierre Cabaniols, and Paul A. Roche

Targeting of SNAP-25 to Membranes Is Mediated by Its Association with the Target SNARE Syntaxin
J. Biol. Chem. 2000 275: 2959-2965. [Abstract] [Full Text] [PDF]  

Kazuyo Hirao, Yutaka Hata, Ikuko Yao, Maki Deguchi, Hiroshi Kawabe, Akira Mizoguchi, and Yoshimi Takai

Three Isoforms of Synaptic Scaffolding Molecule and Their Characterization. MULTIMERIZATION BETWEEN THE ISOFORMS AND THEIR INTERACTION WITH N-METHYL-D-ASPARTATE RECEPTORS AND SAP90/PSD-95-ASSOCIATED PROTEIN
J. Biol. Chem. 2000 275: 2966-2972. [Abstract] [Full Text] [PDF]  

Enzymology:

Stefan W. Vetter, Yen-Fang Keng, David S. Lawrence, and Zhong-Yin Zhang

Assessment of Protein-tyrosine Phosphatase 1B Substrate Specificity Using "Inverse Alanine Scanning"
J. Biol. Chem. 2000 275: 2265-2268. [Abstract] [Full Text] [PDF]  

Isabelle Saves, Valérie Ozanne, Jacques Dietrich, and Jean-Michel Masson

Inteins of Thermococcus fumicolans DNA Polymerase Are Endonucleases with Distinct Enzymatic Behaviors
J. Biol. Chem. 2000 275: 2335-2341. [Abstract] [Full Text] [PDF]  

Bakary B. Touré, Jon Scott Munzer, Ajoy Basak, Suzanne Benjannet, Jim Rochemont, Claude Lazure, Michel Chrétien, and Nabil G. Seidah

Biosynthesis and Enzymatic Characterization of Human SKI-1/S1P and the Processing of Its Inhibitory Prosegment
J. Biol. Chem. 2000 275: 2349-2358. [Abstract] [Full Text] [PDF]  

H. Leighton LeGros, Jr., Abdel-Baset Halim, Arthur M. Geller, and Malak Kotb

Cloning, Expression, and Functional Characterization of the  Regulatory Subunit of Human Methionine Adenosyltransferase (MAT II)
J. Biol. Chem. 2000 275: 2359-2366. [Abstract] [Full Text] [PDF]  

Sunke Himpel, Werner Tegge, Ronald Frank, Susanne Leder, Hans-Georg Joost, and Walter Becker

Specificity Determinants of Substrate Recognition by the Protein Kinase DYRK1A
J. Biol. Chem. 2000 275: 2431-2438. [Abstract] [Full Text] [PDF]  

Ryan T. Terry-Lorenzo, Masumi Inoue, John H. Connor, Timothy A. J. Haystead, Blaine N. Armbruster, Ram P. Gupta, Carey J. Oliver, and Shirish Shenolikar

Neurofilament-L Is a Protein Phosphatase-1-binding Protein Associated with Neuronal Plasma Membrane and Post-synaptic Density
J. Biol. Chem. 2000 275: 2439-2446. [Abstract] [Full Text] [PDF]  

Eduard Torrents, Girbe Buist, Aimin Liu, Rolf Eliasson, Jan Kok, Isidre Gibert, Astrid Gräslund, and Peter Reichard

The Anaerobic (Class III) Ribonucleotide Reductase from Lactococcus lactis. CATALYTIC PROPERTIES AND ALLOSTERIC REGULATION OF THE PURE ENZYME SYSTEM
J. Biol. Chem. 2000 275: 2463-2471. [Abstract] [Full Text] [PDF]  

Benfang Lei, Chih-Jen Wei, and Shiao-Chun Tu

Action Mechanism of Antitubercular Isoniazid. ACTIVATION BY MYCOBACTERIUM TUBERCULOSIS KatG, ISOLATION, AND CHARACTERIZATION OF InhA INHIBITOR
J. Biol. Chem. 2000 275: 2520-2526. [Abstract] [Full Text] [PDF]  

Shayne K. Morris, Cheryl L. Baird, and Janet E. Lindsley

Steady-state and Rapid Kinetic Analysis of Topoisomerase II Trapped as the Closed-clamp Intermediate by ICRF-193
J. Biol. Chem. 2000 275: 2613-2618. [Abstract] [Full Text] [PDF]  

Matthew W. Olson, M. Margarida Bernardo, Martin Pietila, David C. Gervasi, Marta Toth, Lakshmi P. Kotra, Irina Massova, Shahriar Mobashery, and Rafael Fridman

Characterization of the Monomeric and Dimeric Forms of Latent and Active Matrix Metalloproteinase-9. DIFFERENTIAL RATES FOR ACTIVATION BY STROMELYSIN 1
J. Biol. Chem. 2000 275: 2661-2668. [Abstract] [Full Text] [PDF]  

Margaret Porter, Thomas Schindler, John Kuriyan, and W. Todd Miller

Reciprocal Regulation of Hck Activity by Phosphorylation of Tyr⁵²⁷ and Tyr⁴¹⁶. EFFECT OF INTRODUCING A HIGH AFFINITY INTRAMOLECULAR SH2 LIGAND
J. Biol. Chem. 2000 275: 2721-2726. [Abstract] [Full Text] [PDF]  

Jian P. Lian, Peter G. Marks, Jay Y. Wang, Douglas L. Falls, and John A. Badwey

A Protein Kinase from Neutrophils That Specifically Recognizes Ser-3 in Cofilin
J. Biol. Chem. 2000 275: 2869-2876. [Abstract] [Full Text] [PDF]  

Woojin Jeong, Mee-Kyung Cha, and Il-Han Kim

Thioredoxin-dependent Hydroperoxide Peroxidase Activity of Bacterioferritin Comigratory Protein (BCP) as a New Member of the Thiol-specific Antioxidant Protein (TSA)/Alkyl Hydroperoxide Peroxidase C (AhpC) Family
J. Biol. Chem. 2000 275: 2924-2930. [Abstract] [Full Text] [PDF]  

Membranes and Bioenergetics:

Mark W. Vaughn, Kuang-Tse Huang, Lih Kuo, and James C. Liao

Erythrocytes Possess an Intrinsic Barrier to Nitric Oxide Consumption
J. Biol. Chem. 2000 275: 2342-2348. [Abstract] [Full Text] [PDF]  

Chris van der Does, Jelto Swaving, Wim van Klompenburg, and Arnold J. M. Driessen

Non-bilayer Lipids Stimulate the Activity of the Reconstituted Bacterial Protein Translocase
J. Biol. Chem. 2000 275: 2472-2478. [Abstract] [Full Text] [PDF]  

Baoxue Yang, Norimasa Fukuda, Alfred van Hoek, Michael A. Matthay, Tonghui Ma, and A. S. Verkman

Carbon Dioxide Permeability of Aquaporin-1 Measured in Erythrocytes and Lung of Aquaporin-1 Null Mice and in Reconstituted Proteoliposomes
J. Biol. Chem. 2000 275: 2686-2692. [Abstract] [Full Text] [PDF]  

Jie Zhang, Michael C. Sanguinetti, Hubert Kwiecinski, and Louis J. Ptacek

Mechanism of Inverted Activation of ClC-1 Channels Caused by a Novel Myotonia Congenita Mutation
J. Biol. Chem. 2000 275: 2999-3005. [Abstract] [Full Text] [PDF]  

Nucleic Acids, Protein Synthesis, and Molecular Genetics:

Liu Li, Leo R. Otake, Yu-xin Xu, and Shulamit Michaeli

The trans-Spliceosomal U4 RNA from the Monogenetic Trypanosomatid Leptomonas collosoma. CLONING AND IDENTIFICATION OF A TRANSCRIBED tRNA-LIKE ELEMENT THAT CONTROLS ITS EXPRESSION
J. Biol. Chem. 2000 275: 2259-2264. [Abstract] [Full Text] [PDF]  

Sally A. Hemming and Aled M. Edwards

Yeast RNA Polymerase II Subunit RPB9. MAPPING OF DOMAINS REQUIRED FOR TRANSCRIPTION ELONGATION
J. Biol. Chem. 2000 275: 2288-2294. [Abstract] [Full Text] [PDF]  

Gerardo I. Aizencang, David F. Bishop, Douglas Forrest, Kenneth H. Astrin, and Robert J. Desnick

Uroporphyrinogen III Synthase. AN ALTERNATIVE PROMOTER CONTROLS ERYTHROID-SPECIFIC EXPRESSION IN THE MURINE GENE
J. Biol. Chem. 2000 275: 2295-2304. [Abstract] [Full Text] [PDF]  

Erin T. Strovel, Dianqing Wu, and Daniel J. Sussman

Protein Phosphatase 2C Dephosphorylates Axin and Activates LEF-1-dependent Transcription
J. Biol. Chem. 2000 275: 2399-2403. [Abstract] [Full Text] [PDF]  

Katarína Kosalková, Ana T. Marcos, Francisco Fierro, Víctor Hernando-Rico, Santiago Gutiérrez, and Juan F. Martín

A Novel Heptameric Sequence (TTAGTAA) Is the Binding Site for a Protein Required for High Level Expression of pcbAB, the First Gene of the Penicillin Biosynthesis in Penicillium chrysogenum
J. Biol. Chem. 2000 275: 2423-2430. [Abstract] [Full Text] [PDF]  

Roberto Spurio, Letizia Brandi, Enrico Caserta, Cynthia L. Pon, Claudio O. Gualerzi, Rolf Misselwitz, Christoph Krafft, Karin Welfle, and Heinz Welfle

The C-terminal Subdomain (IF2 C-2) Contains the Entire fMet-tRNA Binding Site of Initiation Factor IF2
J. Biol. Chem. 2000 275: 2447-2454. [Abstract] [Full Text] [PDF]  

John Bradsher, Frederic Coin, and Jean-Marc Egly

Distinct Roles for the Helicases of TFIIH in Transcript Initiation and Promoter Escape
J. Biol. Chem. 2000 275: 2532-2538. [Abstract] [Full Text] [PDF]  

Lucia Faccio, Carlo Fusco, Ang Chen, Stefano Martinotti, Joseph V. Bonventre, and Antonis S. Zervos

Characterization of a Novel Human Serine Protease That Has Extensive Homology to Bacterial Heat Shock Endoprotease HtrA and Is Regulated by Kidney Ischemia
J. Biol. Chem. 2000 275: 2581-2588. [Abstract] [Full Text] [PDF]  

Olivier Rohr, Christian Schwartz, Christiane Hery, Dominique Aunis, Marc Tardieu, and Evelyne Schaeffer

The Nuclear Receptor Chicken Ovalbumin Upstream Promoter Transcription Factor Interacts with HIV-1 Tat and Stimulates Viral Replication in Human Microglial Cells
J. Biol. Chem. 2000 275: 2654-2660. [Abstract] [Full Text] [PDF]  

Jeremy R. Graff, Edward Gabrielson, Hiraoki Fujii, Stephen B. Baylin, and James G. Herman

Methylation Patterns of the E-cadherin 5' CpG Island Are Unstable and Reflect the Dynamic, Heterogeneous Loss of E-cadherin Expression during Metastatic Progression
J. Biol. Chem. 2000 275: 2727-2732. [Abstract] [Full Text] [PDF]  

Mark A. Schumacher, Irene Moff, Sharmila P. Sudanagunta, and Jon D. Levine

Molecular Cloning of an N-terminal Splice Variant of the Capsaicin Receptor. LOSS OF N-TERMINAL DOMAIN SUGGESTS FUNCTIONAL DIVERGENCE AMONG CAPSAICIN RECEPTOR SUBTYPES
J. Biol. Chem. 2000 275: 2756-2762. [Abstract] [Full Text] [PDF]  

Ying Zhang and Maria L. Dufau

Nuclear Orphan Receptors Regulate Transcription of the Gene for the Human Luteinizing Hormone Receptor
J. Biol. Chem. 2000 275: 2763-2770. [Abstract] [Full Text] [PDF]  

Li Chen and Erik Bateman

Linker Scanning Analysis of TBP Promoter Binding Factor DNA Binding, Activation, and Repression Domains
J. Biol. Chem. 2000 275: 2771-2776. [Abstract] [Full Text] [PDF]  

Timothy K. MacLachlan, Kumaravel Somasundaram, Magda Sgagias, Yelena Shifman, Ruth J. Muschel, Kenneth H. Cowan, and Wafik S. El-Deiry

BRCA1 Effects on the Cell Cycle and the DNA Damage Response Are Linked to Altered Gene Expression
J. Biol. Chem. 2000 275: 2777-2785. [Abstract] [Full Text] [PDF]  

Cindy L. Luongo, Karin M. Reinisch, Stephen C. Harrison, and Max L. Nibert

Identification of the Guanylyltransferase Region and Active Site in Reovirus mRNA Capping Protein 2
J. Biol. Chem. 2000 275: 2804-2810. [Abstract] [Full Text] [PDF]  

Kyle Garver and Peixuan Guo

Mapping the Inter-RNA Interaction of Bacterial Virus Phi29 Packaging RNA by Site-specific Photoaffinity Cross-linking
J. Biol. Chem. 2000 275: 2817-2824. [Abstract] [Full Text] [PDF]  

Ningwu Huang and Walter L. Miller

Cloning of Factors Related to HIV-inducible LBP Proteins That Regulate Steroidogenic Factor-1-independent Human Placental Transcription of the Cholesterol Side-chain Cleavage Enzyme, P450scc
J. Biol. Chem. 2000 275: 2852-2858. [Abstract] [Full Text] [PDF]  

Douglas J. Swanson, Megumi Adachi, and Elaine J. Lewis

The Homeodomain Protein Arix Promotes Protein Kinase A-dependent Activation of the Dopamine -Hydroxylase Promoter through Multiple Elements and Interaction with the Coactivator cAMP-response Element-binding Protein-binding Protein
J. Biol. Chem. 2000 275: 2911-2923. [Abstract] [Full Text] [PDF]  

Deborah A. Sampson, Mercedes E. Arana, and Paul E. Boehmer

Cysteine 111 Affects Coupling of Single-stranded DNA Binding to ATP Hydrolysis in the Herpes Simplex Virus Type-1 Origin-binding Protein
J. Biol. Chem. 2000 275: 2931-2937. [Abstract] [Full Text] [PDF]  

Deepak Kumar, Theresa L. Whiteside, and Usha Kasid

Identification of a Novel Tumor Necrosis Factor--inducible Gene, SCC-S2, Containing the Consensus Sequence of a Death Effector Domain of Fas-associated Death Domain-like Interleukin- 1-converting Enzyme-inhibitory Protein
J. Biol. Chem. 2000 275: 2973-2978. [Abstract] [Full Text] [PDF]  

Zhen Hu, Shengkan Jin, and Kathleen W. Scotto

Transcriptional Activation of the MDR1 Gene by UV Irradiation. ROLE OF NF-Y AND Sp1
J. Biol. Chem. 2000 275: 2979-2985. [Abstract] [Full Text] [PDF]  

Koen Kas, Eduardo Finger, Franck Grall, Xuesong Gu, Yasmin Akbarali, Jay Boltax, Avi Weiss, Peter Oettgen, Rosana Kapeller, and Towia A. Libermann

ESE-3, a Novel Member of an Epithelium-specific Ets Transcription Factor Subfamily, Demonstrates Different Target Gene Specificity from ESE-1
J. Biol. Chem. 2000 275: 2986-2998. [Abstract] [Full Text] [PDF]  

Brandon Ason, Jeffrey G. Bertram, Manju M. Hingorani, Joseph M. Beechem, Mike O'Donnell, Myron F. Goodman, and Linda B. Bloom

A Model for Escherichia coli DNA Polymerase III Holoenzyme Assembly at Primer/Template Ends. DNA TRIGGERS A CHANGE IN BINDING SPECIFICITY OF THE  COMPLEX CLAMP LOADER
J. Biol. Chem. 2000 275: 3006-3015. [Abstract] [Full Text] [PDF]  

Protein Chemistry and Structure:

Hiroshi Kawaide, Takeshi Sassa, and Yuji Kamiya

Functional Analysis of the Two Interacting Cyclase Domains in ent-Kaurene Synthase from the Fungus Phaeosphaeria sp. L487 and a Comparison with Cyclases from Higher Plants
J. Biol. Chem. 2000 275: 2276-2280. [Abstract] [Full Text] [PDF]  

Angela Schulz, Robert Grosse, Günter Schultz, Thomas Gudermann, and Torsten Schöneberg

Structural Implication for Receptor Oligomerization from Functional Reconstitution Studies of Mutant V2 Vasopressin Receptors
J. Biol. Chem. 2000 275: 2381-2389. [Abstract] [Full Text] [PDF]  

Miklós Nyitrai, Gábor Hild, András Lukács, Emöke Bódis, and Béla Somogyi

Conformational Distributions and Proximity Relationships in the Rigor Complex of Actin and Myosin Subfragment-1
J. Biol. Chem. 2000 275: 2404-2409. [Abstract] [Full Text] [PDF]  

Jose Cosme and Eric F. Johnson

Engineering Microsomal Cytochrome P450 2C5 to Be a Soluble, Monomeric Enzyme. MUTATIONS THAT ALTER AGGREGATION, PHOSPHOLIPID DEPENDENCE OF CATALYSIS, AND MEMBRANE BINDING
J. Biol. Chem. 2000 275: 2545-2553. [Abstract] [Full Text] [PDF]  

Julie A. Morrow, Kay S. Arnold, Jun Dong, Maureen E. Balestra, Thomas L. Innerarity, and Karl H. Weisgraber

Effect of Arginine 172 on the Binding of Apolipoprotein E to the Low Density Lipoprotein Receptor
J. Biol. Chem. 2000 275: 2576-2580. [Abstract] [Full Text] [PDF]  

Eileen K. Jaffe, Marina Volin, Colleen R. Bronson-Mullins, Roland L. Dunbrack, Jr., Jukka Kervinen, Jacob Martins, Jack F. Quinlan, Jr., Matthew H. Sazinsky, Erica M. Steinhouse, and Anthony T. Yeung

An Artificial Gene for Human Porphobilinogen Synthase Allows Comparison of an Allelic Variation Implicated in Susceptibility to Lead Poisoning
J. Biol. Chem. 2000 275: 2619-2626. [Abstract] [Full Text] [PDF]  

Steven Swift, Paul J. Sheridan, Lidija Covic, and Athan Kuliopulos

PAR1 Thrombin Receptor-G Protein Interactions. SEPARATION OF BINDING AND COUPLING DETERMINANTS IN THE G SUBUNIT
J. Biol. Chem. 2000 275: 2627-2635. [Abstract] [Full Text] [PDF]  

Zoltán Nemes, Máté Demény, Lyuben N. Marekov, László Fésüs, and Peter M. Steinert

Cholesterol 3-Sulfate Interferes with Cornified Envelope Assembly by Diverting Transglutaminase 1 Activity from the Formation of Cross-links and Esters to the Hydrolysis of Glutamine
J. Biol. Chem. 2000 275: 2636-2646. [Abstract] [Full Text] [PDF]  

Michael Natochin, Khakim G. Muradov, Randall L. McEntaffer, and Nikolai O. Artemyev

Rhodopsin Recognition by Mutant G_s Containing C-terminal Residues of Transducin
J. Biol. Chem. 2000 275: 2669-2675. [Abstract] [Full Text] [PDF]  

Matteo Villain, Patricia L. Jackson, Michael K. Manion, Wen-Ji Dong, Zhengchang Su, Giorgio Fassina, Tonny M. Johnson, Ted T. Sakai, N. Rama Krishna, and J. Edwin Blalock

De Novo Design of Peptides Targeted to the EF Hands of Calmodulin
J. Biol. Chem. 2000 275: 2676-2685. [Abstract] [Full Text] [PDF]  

J. David Farrar, Janice D. Smith, Theresa L. Murphy, and Kenneth M. Murphy

Recruitment of Stat4 to the Human Interferon-/ Receptor Requires Activated Stat2
J. Biol. Chem. 2000 275: 2693-2697. [Abstract] [Full Text] [PDF]  

Jennifer L. Meagher, Steven T. Olson, and Peter G. W. Gettins

Critical Role of the Linker Region between Helix D and Strand 2A in Heparin Activation of Antithrombin
J. Biol. Chem. 2000 275: 2698-2704. [Abstract] [Full Text] [PDF]  

Dongli Hu, Michael Crist, Xiaoqun Duan, Florante A. Quiocho, and Frederick S. Gimble

Probing the Structure of the PI-SceI-DNA Complex by Affinity Cleavage and Affinity Photocross-linking
J. Biol. Chem. 2000 275: 2705-2712. [Abstract] [Full Text] [PDF]  

David Hui, Carla Morden, Fang Zhang, and Victor Ling

Combinatorial Analysis of the Structural Requirements of the Escherichia coli Hemolysin Signal Sequence
J. Biol. Chem. 2000 275: 2713-2720. [Abstract] [Full Text] [PDF]  

R. Max Wynn, Jiu-Li Song, and David T. Chuang

GroEL/GroES Promote Dissociation/Reassociation Cycles of a Heterodimeric Intermediate during ₂₂ Protein Assembly. ITERATIVE ANNEALING AT THE QUATERNARY STRUCTURE LEVEL
J. Biol. Chem. 2000 275: 2786-2794. [Abstract] [Full Text] [PDF]  

Arne Wörn, Adrian Auf der Maur, Dominik Escher, Annemarie Honegger, Alcide Barberis, and Andreas Plückthun

Correlation between in Vitro Stability and in Vivo Performance of Anti-GCN4 Intrabodies as Cytoplasmic Inhibitors
J. Biol. Chem. 2000 275: 2795-2803. [Abstract] [Full Text] [PDF]  

Additions and Corrections:

Danielle de Moissac, Hui Zheng, and Lorrie A. Kirshenbaum

Linkage of the BH4 domain of Bcl-2 and the nuclear factor B signaling pathway for suppression of apoptosis.
J. Biol. Chem. 2000 275: 3016. [Full Text] [PDF]  

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