Minireviews:

Timothy F. Osborne

Sterol Regulatory Element-binding Proteins (SREBPs): Key Regulators of Nutritional Homeostasis and Insulin Action
J. Biol. Chem. 2000 275: 32379-32382. Published as JBC Papers in Press 10.1074/jbc.R000017200 [Full Text] [PDF]  

Accelerated Publications:

Christian Cambillau and Jean-Michel Claverie

Structural and Genomic Correlates of Hyperthermostability
J. Biol. Chem. 2000 275: 32383-32386. Published as JBC Papers in Press 10.1074/jbc.C000497200 [Abstract] [Full Text] [PDF]  

Hans-Jürgen Kreienkamp, Heike Zitzer, Eckart D. Gundelfinger, Dietmar Richter, and Tobias M. Böckers

The Calcium-independent Receptor for -Latrotoxin from Human and Rodent Brains Interacts with Members of the ProSAP/SSTRIP/Shank Family of Multidomain Proteins
J. Biol. Chem. 2000 275: 32387-32390. Published as JBC Papers in Press 10.1074/jbc.C000490200 [Abstract] [Full Text] [PDF]  

DNA: Replication Repair and Recombination:

Fiorella Petronzelli, Antonio Riccio, George D. Markham, Steven H. Seeholzer, Jay Stoerker, Maurizio Genuardi, Anthony T. Yeung, Yoshihiro Matsumoto, and Alfonso Bellacosa

Biphasic Kinetics of the Human DNA Repair Protein MED1 (MBD4), a Mismatch-specific DNA N-Glycosylase
J. Biol. Chem. 2000 275: 32422-32429. Published as JBC Papers in Press 10.1074/jbc.M004535200 [Abstract] [Full Text] [PDF]  

Satoshi Okano, Shin-ichiro Kanno, Satoshi Nakajima, and Akira Yasui

Cellular Responses and Repair of Single-strand Breaks Introduced by UV Damage Endonuclease in Mammalian Cells
J. Biol. Chem. 2000 275: 32635-32641. Published as JBC Papers in Press 10.1074/jbc.M004085200 [Abstract] [Full Text] [PDF]  

Motoshi Suzuki, Shonen Yoshida, Elinor T. Adman, A. Blank, and Lawrence A. Loeb

Thermus aquaticus DNA Polymerase I Mutants with Altered Fidelity. INTERACTING MUTATIONS IN THE O-HELIX
J. Biol. Chem. 2000 275: 32728-32735. Published as JBC Papers in Press 10.1074/jbc.M000097200 [Abstract] [Full Text] [PDF]  

Franca Majone and Kuan-Teh Jeang

Clastogenic Effect of the Human T-cell Leukemia Virus Type I Tax Oncoprotein Correlates with Unstabilized DNA Breaks
J. Biol. Chem. 2000 275: 32906-32910. Published as JBC Papers in Press 10.1074/jbc.C000538200 [Abstract] [Full Text] [PDF]  

Livnat Uliel, Pnina Weisman-Shomer, Hely Oren-Jazan, Terry Newcomb, Lawrence A. Loeb, and Michael Fry

Human Ku Antigen Tightly Binds and Stabilizes a Tetrahelical Form of the Fragile X Syndrome d(CGG)_n Expanded Sequence
J. Biol. Chem. 2000 275: 33134-33141. Published as JBC Papers in Press 10.1074/jbc.M005542200 [Abstract] [Full Text] [PDF]  

Genes: Structure and Regulation:

Nicholas F. Marshall and Michael E. Dahmus

C-terminal Domain Phosphatase Sensitivity of RNA Polymerase II in Early Elongation Complexes on the HIV-1 and Adenovirus 2 Major Late Templates
J. Biol. Chem. 2000 275: 32430-32437. Published as JBC Papers in Press 10.1074/jbc.M005898200 [Abstract] [Full Text] [PDF]  

Ulla H. Dormer, John Westwater, Niall F. McLaren, Nicholas A. Kent, Jane Mellor, and Derek J. Jamieson

Cadmium-inducible Expression of the Yeast GSH1 Gene Requires a Functional Sulfur-Amino Acid Regulatory Network
J. Biol. Chem. 2000 275: 32611-32616. Published as JBC Papers in Press 10.1074/jbc.M004167200 [Abstract] [Full Text] [PDF]  

Roger R. Beerli, Ulrich Schopfer, Birgit Dreier, and Carlos F. Barbas, III

Chemically Regulated Zinc Finger Transcription Factors
J. Biol. Chem. 2000 275: 32617-32627. Published as JBC Papers in Press 10.1074/jbc.M005108200 [Abstract] [Full Text] [PDF]  

Greg Dean, David A. Young, Dylan R. Edwards, and Ian M. Clark

The Human Tissue Inhibitor of Metalloproteinases (TIMP)-1 Gene Contains Repressive Elements within the Promoter and Intron 1
J. Biol. Chem. 2000 275: 32664-32671. Published as JBC Papers in Press 10.1074/jbc.275.42.32664 [Abstract] [Full Text] [PDF]  

Hengli Tang and Flossie Wong-Staal

Specific Interaction between RNA Helicase A and Tap, Two Cellular Proteins That Bind to the Constitutive Transport Element of Type D Retrovirus
J. Biol. Chem. 2000 275: 32694-32700. Published as JBC Papers in Press 10.1074/jbc.M003933200 [Abstract] [Full Text] [PDF]  

Beate Ritz-Laser, Anne Estreicher, Benoit Gauthier, and Jacques Philippe

The Paired Homeodomain Transcription Factor Pax-2 Is Expressed in the Endocrine Pancreas and Transactivates the Glucagon Gene Promoter
J. Biol. Chem. 2000 275: 32708-32715. Published as JBC Papers in Press 10.1074/jbc.M005704200 [Abstract] [Full Text] [PDF]  

Laurence Baudoux, Patricia Defechereux, Bernard Rentier, and Jacques Piette

Gene Activation by Varicella-Zoster Virus IE4 Protein Requires Its Dimerization and Involves Both the Arginine-rich Sequence, the Central Part, and the Carboxyl-terminal Cysteine-rich Region
J. Biol. Chem. 2000 275: 32822-32831. Published as JBC Papers in Press 10.1074/jbc.M001444200 [Abstract] [Full Text] [PDF]  

Etienne Lefai, Miguel A. Fernández-Moreno, Anuradha Alahari, Laurie S. Kaguni, and Rafael Garesse

Differential Regulation of the Catalytic and Accessory Subunit Genes of Drosophila Mitochondrial DNA Polymerase
J. Biol. Chem. 2000 275: 33123-33133. Published as JBC Papers in Press 10.1074/jbc.M003024200 [Abstract] [Full Text] [PDF]  

Yukio Ikeda, Akira Sugawara, Yoshihiro Taniyama, Akira Uruno, Kazuhiko Igarashi, Shuji Arima, Sadayoshi Ito, and Kazuhisa Takeuchi

Suppression of Rat Thromboxane Synthase Gene Transcription by Peroxisome Proliferator-activated Receptor in Macrophages via an Interaction with NRF2
J. Biol. Chem. 2000 275: 33142-33150. Published as JBC Papers in Press 10.1074/jbc.M002319200 [Abstract] [Full Text] [PDF]  

RNA: Structure Metabolism and Catalysis:

Koichi Inoue, Takayuki Mizuno, Kazuhiro Wada, and Masatoshi Hagiwara

Novel RING Finger Proteins, Air1p and Air2p, Interact with Hmt1p and Inhibit the Arginine Methylation of Npl3p
J. Biol. Chem. 2000 275: 32793-32799. Published as JBC Papers in Press 10.1074/jbc.M004560200 [Abstract] [Full Text] [PDF]  

Julia A. Chekanova, Randal J. Shaw, Michelle A. Wills, and Dmitry A. Belostotsky

Poly(A) Tail-dependent Exonuclease AtRrp41p from Arabidopsis thaliana Rescues 5.8 S rRNA Processing and mRNA Decay Defects of the Yeast ski6 Mutant and Is Found in an Exosome-sized Complex in Plant and Yeast Cells
J. Biol. Chem. 2000 275: 33158-33166. Published as JBC Papers in Press 10.1074/jbc.M005493200 [Abstract] [Full Text] [PDF]  

Protein Synthesis Post-Translation Modification and Degradation:

Tomohiro Sawa, Takaaki Akaike, and Hiroshi Maeda

Tyrosine Nitration by Peroxynitrite Formed from Nitric Oxide and Superoxide Generated by Xanthine Oxidase
J. Biol. Chem. 2000 275: 32467-32474. Published as JBC Papers in Press 10.1074/jbc.M910169199 [Abstract] [Full Text] [PDF]  

Julie Soutourina, Pierre Plateau, and Sylvain Blanquet

Metabolism of D-Aminoacyl-tRNAs in Escherichia coli and Saccharomyces cerevisiae Cells
J. Biol. Chem. 2000 275: 32535-32542. Published as JBC Papers in Press 10.1074/jbc.M005166200 [Abstract] [Full Text] [PDF]  

Daniela Palmieri, Laura Camardella, Valentina Ulivi, Gaetana Guasco, and Paola Manduca

Trimer Carboxyl Propeptide of Collagen I Produced by Mature Osteoblasts Is Chemotactic for Endothelial Cells
J. Biol. Chem. 2000 275: 32658-32663. Published as JBC Papers in Press 10.1074/jbc.M002698200 [Abstract] [Full Text] [PDF]  

Adam Frankel and Steven Clarke

PRMT3 Is a Distinct Member of the Protein Arginine N-Methyltransferase Family. CONFERRAL OF SUBSTRATE SPECIFICITY BY A ZINC-FINGER DOMAIN
J. Biol. Chem. 2000 275: 32974-32982. Published as JBC Papers in Press 10.1074/jbc.M006445200 [Abstract] [Full Text] [PDF]  

Amanda J. Fosang, Karena Last, Heather Stanton, David B. Weeks, Ian K. Campbell, Timothy E. Hardingham, and Rosalind M. Hembry

Generation and Novel Distribution of Matrix Metalloproteinase-derived Aggrecan Fragments in Porcine Cartilage Explants
J. Biol. Chem. 2000 275: 33027-33037. Published as JBC Papers in Press 10.1074/jbc.M910207199 [Abstract] [Full Text] [PDF]  

Francesca A. Mercuri, Rose A. Maciewicz, Jonathan Tart, Karena Last, and Amanda J. Fosang

Mutations in the Interglobular Domain of Aggrecan Alter Matrix Metalloproteinase and Aggrecanase Cleavage Patterns. EVIDENCE THAT MATRIX METALLOPROTEINASE CLEAVAGE INTERFERES WITH AGGRECANASE ACTIVITY
J. Biol. Chem. 2000 275: 33038-33045. Published as JBC Papers in Press 10.1074/jbc.275.42.33038 [Abstract] [Full Text] [PDF]  

Genomics Proteomics and Bioinformatics:

Emine Cavdar Koc, William Burkhart, Kevin Blackburn, Arthur Moseley, Hasan Koc, and Linda L. Spremulli

A Proteomics Approach to the Identification of Mammalian Mitochondrial Small Subunit Ribosomal Proteins
J. Biol. Chem. 2000 275: 32585-32591. Published as JBC Papers in Press 10.1074/jbc.M003596200 [Abstract] [Full Text] [PDF]  

Protein Structure and Folding:

J. Michael McIntosh, Gloria O. Corpuz, Richard T. Layer, James E. Garrett, John D. Wagstaff, Grzegorz Bulaj, Alexandra Vyazovkina, Doju Yoshikami, Lourdes J. Cruz, and Baldomero M. Olivera

Isolation and Characterization of a Novel Conus Peptide with Apparent Antinociceptive Activity
J. Biol. Chem. 2000 275: 32391-32397. Published as JBC Papers in Press 10.1074/jbc.M003619200 [Abstract] [Full Text] [PDF]  

Brian D. Johnson, Ahmed Chadli, Sara J. Felts, Ilhem Bouhouche, Maria G. Catelli, and David O. Toft

Hsp90 Chaperone Activity Requires the Full-length Protein and Interaction among Its Multiple Domains
J. Biol. Chem. 2000 275: 32499-32507. Published as JBC Papers in Press 10.1074/jbc.M005195200 [Abstract] [Full Text] [PDF]  

Esther J. Tomlinson and Stuart J. Ferguson

Loss of Either of the Two Heme-binding Cysteines from a Class I c-Type Cytochrome Has a Surprisingly Small Effect on Physicochemical Properties
J. Biol. Chem. 2000 275: 32530-32534. Published as JBC Papers in Press 10.1074/jbc.M004022200 [Abstract] [Full Text] [PDF]  

Isabella Marini, Roberta Moschini, Antonella Del Corso, and Umberto Mura

Complete Protection by -Crystallin of Lens Sorbitol Dehydrogenase Undergoing Thermal Stress
J. Biol. Chem. 2000 275: 32559-32565. Published as JBC Papers in Press 10.1074/jbc.M006133200 [Abstract] [Full Text] [PDF]  

Vincent Chopin, Michel Salzet, Jean-luc Baert, Franck Vandenbulcke, Pierre-Eric Sautière, Jean-Pierre Kerckaert, and Jean Malecha

Therostasin, a Novel Clotting Factor Xa Inhibitor from the Rhynchobdellid Leech, Theromyzon tessulatum
J. Biol. Chem. 2000 275: 32701-32707. Published as JBC Papers in Press 10.1074/jbc.M909217199 [Abstract] [Full Text] [PDF]  

Tom Huxford, Shiva Malek, and Gourisankar Ghosh

Preparation and Crystallization of Dynamic NF-B·IB Complexes
J. Biol. Chem. 2000 275: 32800-32806. Published as JBC Papers in Press 10.1074/jbc.M006037200 [Abstract] [Full Text] [PDF]  

David M. Hoover, Kanaghalagatta R. Rajashankar, Robert Blumenthal, Anu Puri, Joost J. Oppenheim, Oleg Chertov, and Jacek Lubkowski

The Structure of Human -Defensin-2 Shows Evidence of Higher Order Oligomerization
J. Biol. Chem. 2000 275: 32911-32918. Published as JBC Papers in Press 10.1074/jbc.M006098200 [Abstract] [Full Text] [PDF]  

Christopher A. Miles, Alina Sionkowska, Sarah L. Hulin, Trevor J. Sims, Nicholas C. Avery, and Allen J. Bailey

Identification of an Intermediate State in the Helix-Coil Degradation of Collagen by Ultraviolet Light
J. Biol. Chem. 2000 275: 33014-33020. Published as JBC Papers in Press 10.1074/jbc.M002346200 [Abstract] [Full Text] [PDF]  

Enzyme Catalysis and Regulation:

Vasantha P. Mutucumarana, Darrel W. Stafford, Thomas B. Stanley, Da-Yun Jin, Jesus Solera, Benjamin Brenner, Robert Azerad, and Sheue-Mei Wu

Expression and Characterization of the Naturally Occurring Mutation L394R in Human -Glutamyl Carboxylase
J. Biol. Chem. 2000 275: 32572-32577. Published as JBC Papers in Press 10.1074/jbc.M006808200 [Abstract] [Full Text] [PDF]  

Philipp Kaldis, Aiyang Cheng, and Mark J. Solomon

The Effects of Changing the Site of Activating Phosphorylation in CDK2 from Threonine to Serine
J. Biol. Chem. 2000 275: 32578-32584. Published as JBC Papers in Press 10.1074/jbc.M003212200 [Abstract] [Full Text] [PDF]  

Michaela Windfuhr, Arnd Manegold, Martina Mühlenhoff, Matthias Eckhardt, and Rita Gerardy-Schahn

Molecular Defects That Cause Loss of Polysialic Acid in the Complementation Group 2A10
J. Biol. Chem. 2000 275: 32861-32870. Published as JBC Papers in Press 10.1074/jbc.M003507200 [Abstract] [Full Text] [PDF]  

Masaya Oki and Takeharu Nishimoto

Yrb1p Interaction with the Gsp1p C Terminus Blocks Mog1p Stimulation of GTP Release from Gsp1p
J. Biol. Chem. 2000 275: 32894-32900. Published as JBC Papers in Press 10.1074/jbc.M910251199 [Abstract] [Full Text] [PDF]  

Masayuki Sudoh, Toshikazu Yamazaki, Kazunao Masubuchi, Mikio Taniguchi, Nobuo Shimma, Mikio Arisawa, and Hisafumi Yamada-Okabe

Identification of a Novel Inhibitor Specific to the Fungal Chitin Synthase. INHIBITION OF CHITIN SYNTHASE 1 ARRESTS THE CELL GROWTH, BUT INHIBITION OF CHITIN SYNTHASE 1 AND 2 IS LETHAL IN THE PATHOGENIC FUNGUS CANDIDA ALBICANS
J. Biol. Chem. 2000 275: 32901-32905. Published as JBC Papers in Press 10.1074/jbc.M003634200 [Abstract] [Full Text] [PDF]  

Hiroyuki Wariishi, Daisuke Nonaka, Toru Johjima, Nobufumi Nakamura, Yoshinori Naruta, Shunsuke Kubo, and Keiichi Fukuyama

Direct Binding of Hydroxylamine to the Heme Iron of Arthromyces ramosus Peroxidase. SUBSTRATE ANALOGUE THAT INHIBITS COMPOUND I FORMATION IN A COMPETITIVE MANNER
J. Biol. Chem. 2000 275: 32919-32924. Published as JBC Papers in Press 10.1074/jbc.M004223200 [Abstract] [Full Text] [PDF]  

Jared L. Cartwright, Lakhdar Gasmi, David G. Spiller, and Alexander G. McLennan

The Saccharomyces cerevisiae PCD1 Gene Encodes a Peroxisomal Nudix Hydrolase Active toward Coenzyme A and Its Derivatives
J. Biol. Chem. 2000 275: 32925-32930. Published as JBC Papers in Press 10.1074/jbc.M005015200 [Abstract] [Full Text] [PDF]  

Oliver Hiller, Andrea Lichte, André Oberpichler, Andreas Kocourek, and Harald Tschesche

Matrix Metalloproteinases Collagenase-2, Macrophage Elastase, Collagenase-3, and Membrane Type 1-Matrix Metalloproteinase Impair Clotting by Degradation of Fibrinogen and Factor XII
J. Biol. Chem. 2000 275: 33008-33013. Published as JBC Papers in Press 10.1074/jbc.M001836200 [Abstract] [Full Text] [PDF]  

Peter Reichard, Rolf Eliasson, Rolf Ingemarson, and Lars Thelander

Cross-talk between the Allosteric Effector-binding Sites in Mouse Ribonucleotide Reductase
J. Biol. Chem. 2000 275: 33021-33026. Published as JBC Papers in Press 10.1074/jbc.M005337200 [Abstract] [Full Text] [PDF]  

Metabolism and Bioenergetics:

Maria J. Muñoz-Alonso, Ghislaine Guillemain, Nadim Kassis, Jean Girard, Anne-Françoise Burnol, and Armelle Leturque

A Novel Cytosolic Dual Specificity Phosphatase, Interacting with Glucokinase, Increases Glucose Phosphorylation Rate
J. Biol. Chem. 2000 275: 32406-32412. Published as JBC Papers in Press 10.1074/jbc.M000841200 [Abstract] [Full Text] [PDF]  

Christopher D. Reiter, Ru-Jeng Teng, and Joseph S. Beckman

Superoxide Reacts with Nitric Oxide to Nitrate Tyrosine at Physiological pH via Peroxynitrite
J. Biol. Chem. 2000 275: 32460-32466. Published as JBC Papers in Press 10.1074/jbc.M910433199 [Abstract] [Full Text] [PDF]  

Young Hee Ko, Joanne Hullihen, Sangjin Hong, and Peter L. Pedersen

Mitochondrial F₀F₁ ATP Synthase. SUBUNIT REGIONS ON THE F₁ MOTOR SHIELDED BY F₀, FUNCTIONAL SIGNIFICANCE, AND EVIDENCE FOR AN INVOLVEMENT OF THE UNIQUE F₀ SUBUNIT F₆
J. Biol. Chem. 2000 275: 32931-32939. Published as JBC Papers in Press 10.1074/jbc.M004453200 [Abstract] [Full Text] [PDF]  

Glycobiology and Extracellular Matrices:

Kazuhiro Mio, Odile Carrette, Howard I. Maibach, and Robert Stern

Evidence That the Serum Inhibitor of Hyaluronidase May Be a Member of the Inter--inhibitor Family
J. Biol. Chem. 2000 275: 32413-32421. Published as JBC Papers in Press 10.1074/jbc.M005428200 [Abstract] [Full Text] [PDF]  

Tomohiko Taguchi, Tomoya Ogawa, Sadako Inoue, Yasuo Inoue, Yoshihiro Sakamoto, Hiroaki Korekane, and Naoyuki Taniguchi

Purification and Characterization of UDP-GlcNAc: GlcNAc1-6(GlcNAc1-2)Man1-R [GlcNAc to Man]-1, 4-N-acetylglucosaminyltransferase VI from Hen Oviduct
J. Biol. Chem. 2000 275: 32598-32602. Published as JBC Papers in Press 10.1074/jbc.M004673200 [Abstract] [Full Text] [PDF]  

Yue Zhang and Qian Chen

Changes of Matrilin Forms during Endochondral Ossification. MOLECULAR BASIS OF OLIGOMERIC ASSEMBLY
J. Biol. Chem. 2000 275: 32628-32634. Published as JBC Papers in Press 10.1074/jbc.M002594200 [Abstract] [Full Text] [PDF]  

Richard E. Bruehl, Carolyn R. Bertozzi, and Steven D. Rosen

Minimal Sulfated Carbohydrates for Recognition by L-selectin and the MECA-79 Antibody
J. Biol. Chem. 2000 275: 32642-32648. Published as JBC Papers in Press 10.1074/jbc.M001703200 [Abstract] [Full Text] [PDF]  

Tianmin Liu, Zhongwu Guo, Qingling Yang, Subash Sad, and Harold J. Jennings

Biochemical Engineering of Surface 2-8 Polysialic Acid for Immunotargeting Tumor Cells
J. Biol. Chem. 2000 275: 32832-32836. Published as JBC Papers in Press 10.1074/jbc.C000573200 [Abstract] [Full Text] [PDF]  

György Csordás, Manoranjan Santra, Charles C. Reed, Inge Eichstetter, David J. McQuillan, Danielle Gross, Matthew A. Nugent, György Hajnóczky, and Renato V. Iozzo

Sustained Down-regulation of the Epidermal Growth Factor Receptor by Decorin. A MECHANISM FOR CONTROLLING TUMOR GROWTH IN VIVO
J. Biol. Chem. 2000 275: 32879-32887. Published as JBC Papers in Press 10.1074/jbc.M005609200 [Abstract] [Full Text] [PDF]  

Shinji Honda, Masahide Kashiwagi, Kentaro Miyamoto, Yoshio Takei, and Shigehisa Hirose

Multiplicity, Structures, and Endocrine and Exocrine Natures of Eel Fucose-binding Lectins
J. Biol. Chem. 2000 275: 33151-33157. Published as JBC Papers in Press 10.1074/jbc.M002337200 [Abstract] [Full Text] [PDF]  

Lipids and Lipoproteins:

Toshihiro Tanioka, Yoshihito Nakatani, Natsuki Semmyo, Makoto Murakami, and Ichiro Kudo

Molecular Identification of Cytosolic Prostaglandin E₂ Synthase That Is Functionally Coupled with Cyclooxygenase-1 in Immediate Prostaglandin E₂ Biosynthesis
J. Biol. Chem. 2000 275: 32775-32782. Published as JBC Papers in Press 10.1074/jbc.M003504200 [Abstract] [Full Text] [PDF]  

Makoto Murakami, Hiroaki Naraba, Toshihiro Tanioka, Natsuki Semmyo, Yoshihito Nakatani, Fumiaki Kojima, Tomomi Ikeda, Mai Fueki, Akinori Ueno, Sachiko Oh-ishi, and Ichiro Kudo

Regulation of Prostaglandin E₂ Biosynthesis by Inducible Membrane-associated Prostaglandin E₂ Synthase That Acts in Concert with Cyclooxygenase-2
J. Biol. Chem. 2000 275: 32783-32792. Published as JBC Papers in Press 10.1074/jbc.M003505200 [Abstract] [Full Text] [PDF]  

Zhouji Chen, Robin L. Fitzgerald, Maurizio R. Averna, and Gustav Schonfeld

A Targeted Apolipoprotein B-38.9-producing Mutation Causes Fatty Livers in Mice Due to the Reduced Ability of Apolipoprotein B-38.9 to Transport Triglycerides
J. Biol. Chem. 2000 275: 32807-32815. Published as JBC Papers in Press 10.1074/jbc.M004913200 [Abstract] [Full Text] [PDF]  

Henry S. Gibbons, Shanhua Lin, Robert J. Cotter, and Christian R. H. Raetz

Oxygen Requirement for the Biosynthesis of the S-2-Hydroxymyristate Moiety in Salmonella typhimurium Lipid A. FUNCTION OF LpxO, A NEW Fe²⁺/-KETOGLUTARATE-DEPENDENT DIOXYGENASE HOMOLOGUE
J. Biol. Chem. 2000 275: 32940-32949. Published as JBC Papers in Press 10.1074/jbc.M005779200 [Abstract] [Full Text] [PDF]  

Nan Wang, David L. Silver, Philippe Costet, and Alan R. Tall

Specific Binding of ApoA-I, Enhanced Cholesterol Efflux, and Altered Plasma Membrane Morphology in Cells Expressing ABC1
J. Biol. Chem. 2000 275: 33053-33058. Published as JBC Papers in Press 10.1074/jbc.M005438200 [Abstract] [Full Text] [PDF]  

Wei-Yang Zhang, Itsuko Ishii, and Howard S. Kruth

Plasmin-mediated Macrophage Reversal of Low Density Lipoprotein Aggregation
J. Biol. Chem. 2000 275: 33176-33183. Published as JBC Papers in Press 10.1074/jbc.M908714199 [Abstract] [Full Text] [PDF]  

Membrane Transport Structure Function and Biogenesis:

Alexandra M. M. Gouveia, Carlos Reguenga, Márcia E. M. Oliveira, Clara Sá-Miranda, and Jorge E. Azevedo

Characterization of Peroxisomal Pex5p from Rat Liver. Pex5p IN THE Pex5p-Pex14p MEMBRANE COMPLEX IS A TRANSMEMBRANE PROTEIN
J. Biol. Chem. 2000 275: 32444-32451. Published as JBC Papers in Press 10.1074/jbc.M004366200 [Abstract] [Full Text] [PDF]  

Chris T. Coburn, F. F. Knapp, Jr., Maria Febbraio, Arnold L. Beets, Roy L. Silverstein, and Nada A. Abumrad

Defective Uptake and Utilization of Long Chain Fatty Acids in Muscle and Adipose Tissues of CD36 Knockout Mice
J. Biol. Chem. 2000 275: 32523-32529. Published as JBC Papers in Press 10.1074/jbc.M003826200 [Abstract] [Full Text] [PDF]  

Carolina García-Martínez, Cruz Morenilla-Palao, Rosa Planells-Cases, Jaime M. Merino, and Antonio Ferrer-Montiel

Identification of an Aspartic Residue in the P-loop of the Vanilloid Receptor That Modulates Pore Properties
J. Biol. Chem. 2000 275: 32552-32558. Published as JBC Papers in Press 10.1074/jbc.M002391200 [Abstract] [Full Text] [PDF]  

Lee-Lee Ong, Angeline P. C. Lim, Connie P. N. Er, Sergei A. Kuznetsov, and Hanry Yu

Kinectin-Kinesin Binding Domains and Their Effects on Organelle Motility
J. Biol. Chem. 2000 275: 32854-32860. Published as JBC Papers in Press 10.1074/jbc.M005650200 [Abstract] [Full Text] [PDF]  

Aster Legesse-Miller, Yuval Sagiv, Rina Glozman, and Zvulun Elazar

Aut7p, a Soluble Autophagic Factor, Participates in Multiple Membrane Trafficking Processes
J. Biol. Chem. 2000 275: 32966-32973. Published as JBC Papers in Press 10.1074/jbc.M000917200 [Abstract] [Full Text] [PDF]  

Nemat O. Keyhani, Xi-Bing Li, and Saul Roseman

Chitin Catabolism in the Marine Bacterium Vibrio furnissii. IDENTIFICATION AND MOLECULAR CLONING OF A CHITOPORIN
J. Biol. Chem. 2000 275: 33068-33076. Published as JBC Papers in Press 10.1074/jbc.M001041200 [Abstract] [Full Text] [PDF]  

Jae Kweon Park, Nemat O. Keyhani, and Saul Roseman

Chitin Catabolism in the Marine Bacterium Vibrio furnissii. IDENTIFICATION, MOLECULAR CLONING, AND CHARACTERIZATION OF A N,N'-DIACETYLCHITOBIOSE PHOSPHORYLASE
J. Biol. Chem. 2000 275: 33077-33083. Published as JBC Papers in Press 10.1074/jbc.M001042200 [Abstract] [Full Text] [PDF]  

Nemat O. Keyhani, Lai-Xi Wang, Y. C. Lee, and Saul Roseman

The Chitin Disaccharide, N,N'-Diacetylchitobiose, Is Catabolized by Escherichia coli and Is Transported/Phosphorylated by the Phosphoenolpyruvate:Glycose Phosphotransferase System
J. Biol. Chem. 2000 275: 33084-33090. Published as JBC Papers in Press 10.1074/jbc.M001043200 [Abstract] [Full Text] [PDF]  

Nemat O. Keyhani, Olga Boudker, and Saul Roseman

Isolation and Characterization of IIA^Chb, a Soluble Protein of the Enzyme II Complex Required for the Transport/Phosphorylation of N,N'-Diacetylchitobiose in Escherichia coli
J. Biol. Chem. 2000 275: 33091-33101. Published as JBC Papers in Press 10.1074/jbc.M001044200 [Abstract] [Full Text] [PDF]  

Nemat O. Keyhani, Kirsten Bacia, and Saul Roseman

The Transport/Phosphorylation of N,N'-Diacetylchitobiose in Escherichia coli. CHARACTERIZATION OF PHOSPHO-IIB^Chb AND OF A POTENTIAL TRANSITION STATE ANALOGUE IN THE PHOSPHOTRANSFER REACTION BETWEEN THE PROTEINS IIA^Chb AND IIB^Chb
J. Biol. Chem. 2000 275: 33102-33109. Published as JBC Papers in Press 10.1074/jbc.M001045200 [Abstract] [Full Text] [PDF]  

Nemat Keyhani, Michael E. Rodgers, Borries Demeler, Jeffrey C. Hansen, and Saul Roseman

Analytical Sedimentation of the IIA^Chb and IIB^Chb Proteins of the Escherichia coli N,N'-Diacetylchitobiose Phosphotransferase System. DEMONSTRATION OF A MODEL PHOSPHOTRANSFER TRANSITION STATE COMPLEX
J. Biol. Chem. 2000 275: 33110-33115. Published as JBC Papers in Press 10.1074/jbc.M001717200 [Abstract] [Full Text] [PDF]  

Mechanisms Of Signal Transduction:

Rita Raddatz, Amy E. Wilson, Roman Artymyshyn, James A. Bonini, Beth Borowsky, Lakmal W. Boteju, Siqun Zhou, Evguenia V. Kouranova, Raisa Nagorny, Maricel S. Guevarra, Meng Dai, Gabriel S. Lerman, Pierre J. Vaysse, Theresa A. Branchek, Christophe Gerald, Carlos Forray, and Nika Adham

Identification and Characterization of Two Neuromedin U Receptors Differentially Expressed in Peripheral Tissues and the Central Nervous System
J. Biol. Chem. 2000 275: 32452-32459. Published as JBC Papers in Press 10.1074/jbc.M004613200 [Abstract] [Full Text] [PDF]  

Vivianne W. Ding, Rui-Hong Chen, and Frank McCormick

Differential Regulation of Glycogen Synthase Kinase 3 by Insulin and Wnt Signaling
J. Biol. Chem. 2000 275: 32475-32481. Published as JBC Papers in Press 10.1074/jbc.M005342200 [Abstract] [Full Text] [PDF]  

Sébastien S. Hébert, Alex Daviau, Gilles Grondin, Mathieu Latreille, Rémy A. Aubin, and Richard Blouin

The Mixed Lineage Kinase DLK Is Oligomerized by Tissue Transglutaminase during Apoptosis
J. Biol. Chem. 2000 275: 32482-32490. Published as JBC Papers in Press 10.1074/jbc.M006528200 [Abstract] [Full Text] [PDF]  

Hai Wu, Gadiparthi N. Rao, Bosong Dai, and Pomila Singh

Autocrine Gastrins in Colon Cancer Cells Up-regulate Cytochrome c Oxidase Vb and Down-regulate Efflux of Cytochrome c and Activation of Caspase-3
J. Biol. Chem. 2000 275: 32491-32498. Published as JBC Papers in Press 10.1074/jbc.M002458200 [Abstract] [Full Text] [PDF]  

Melanie J. Calvert, Douglas G. Ward, Hylary R. Trayer, and Ian P. Trayer

The Importance of the Carboxyl-terminal Domain of Cardiac Troponin C in Ca²⁺-sensitive Muscle Regulation
J. Biol. Chem. 2000 275: 32508-32515. Published as JBC Papers in Press 10.1074/jbc.M005764200 [Abstract] [Full Text] [PDF]  

Chuanshu Huang, Zhuo Zhang, Min Ding, Jingxia Li, Jianping Ye, Stephen S. Leonard, Han-Ming Shen, Leon Butterworth, Yongju Lu, Max Costa, Yongyut Rojanasakul, Vincent Castranova, Val Vallyathan, and Xianglin Shi

Vanadate Induces p53 Transactivation through Hydrogen Peroxide and Causes Apoptosis
J. Biol. Chem. 2000 275: 32516-32522. Published as JBC Papers in Press 10.1074/jbc.M005366200 [Abstract] [Full Text] [PDF]  

Alexander Abel, Norbert Wittau, Thomas Wieland, Günter Schultz, and Frank Kalkbrenner

Cell Cycle-dependent Coupling of the Vasopressin V_1a Receptor to Different G Proteins
J. Biol. Chem. 2000 275: 32543-32551. Published as JBC Papers in Press 10.1074/jbc.M002171200 [Abstract] [Full Text] [PDF]  

Raya R. Dana, Calvin Eigsti, Kevin L. Holmes, and Thomas L. Leto

A Regulatory Role for ADP-ribosylation Factor 6 (ARF6) in Activation of the Phagocyte NADPH Oxidase
J. Biol. Chem. 2000 275: 32566-32571. Published as JBC Papers in Press 10.1074/jbc.M005406200 [Abstract] [Full Text] [PDF]  

Dan Wang, Sandy D. Westerheide, Julie L. Hanson, and Albert S. Baldwin, Jr.

Tumor Necrosis Factor -induced Phosphorylation of RelA/p65 on Ser⁵²⁹ Is Controlled by Casein Kinase II
J. Biol. Chem. 2000 275: 32592-32597. Published as JBC Papers in Press 10.1074/jbc.M001358200 [Abstract] [Full Text] [PDF]  

Martina Schmidt, Markus Frings, Marie-Luise Mono, Yuanjian Guo, Paschal A. Oude Weernink, Sandrine Evellin, Li Han, and Karl H. Jakobs

G Protein-coupled Receptor-induced Sensitization of Phospholipase C Stimulation by Receptor Tyrosine Kinases
J. Biol. Chem. 2000 275: 32603-32610. Published as JBC Papers in Press 10.1074/jbc.M004784200 [Abstract] [Full Text] [PDF]  

Mark D'Amico, James Hulit, Derek F. Amanatullah, Brian T. Zafonte, Chris Albanese, Boumediene Bouzahzah, Maofu Fu, Leonard H. Augenlicht, Lawrence A. Donehower, Ken-Ichi Takemaru, Randall T. Moon, Roger Davis, Michael P. Lisanti, Michael Shtutman, Jacob Zhurinsky, Avri Ben-Ze'ev, Armelle A. Troussard, Shoukat Dedhar, and Richard G. Pestell

The Integrin-linked Kinase Regulates the Cyclin D1 Gene through Glycogen Synthase Kinase 3 and cAMP-responsive Element-binding Protein-dependent Pathways
J. Biol. Chem. 2000 275: 32649-32657. Published as JBC Papers in Press 10.1074/jbc.M000643200 [Abstract] [Full Text] [PDF]  

Elisa Bofill-Cardona, Oliver Kudlacek, Qiong Yang, Horst Ahorn, Michael Freissmuth, and Christian Nanoff

Binding of Calmodulin to the D₂-Dopamine Receptor Reduces Receptor Signaling by Arresting the G Protein Activation Switch
J. Biol. Chem. 2000 275: 32672-32680. Published as JBC Papers in Press 10.1074/jbc.M002780200 [Abstract] [Full Text] [PDF]  

Su Wol Chung, Bok Yun Kang, Seung Hyun Kim, Youngmi Kim Pak, Daeho Cho, Giorgio Trinchieri, and Tae Sung Kim

Oxidized Low Density Lipoprotein Inhibits Interleukin-12 Production in Lipopolysaccharide-activated Mouse Macrophages via Direct Interactions between Peroxisome Proliferator-activated Receptor- and Nuclear Factor-B
J. Biol. Chem. 2000 275: 32681-32687. Published as JBC Papers in Press 10.1074/jbc.M002577200 [Abstract] [Full Text] [PDF]  

Nikolai P. Skiba, Johnathan A. Hopp, and Vadim Y. Arshavsky

The Effector Enzyme Regulates the Duration of G Protein Signaling in Vertebrate Photoreceptors by Increasing the Affinity between Transducin and RGS Protein
J. Biol. Chem. 2000 275: 32716-32720. Published as JBC Papers in Press 10.1074/jbc.C000413200 [Abstract] [Full Text] [PDF]  

Yong-Sik Kim, Ji-Hwan Ryu, Sung-Jun Han, Kun-Ho Choi, Ki-Bum Nam, In-Hwan Jang, Bruno Lemaitre, Paul T. Brey, and Won-Jae Lee

Gram-negative Bacteria-binding Protein, a Pattern Recognition Receptor for Lipopolysaccharide and -1,3-Glucan That Mediates the Signaling for the Induction of Innate Immune Genes in Drosophila melanogaster Cells
J. Biol. Chem. 2000 275: 32721-32727. Published as JBC Papers in Press 10.1074/jbc.M003934200 [Abstract] [Full Text] [PDF]  

Vladimir Litvak, Donghua Tian, Yoav David Shaul, and Sima Lev

Targeting of PYK2 to Focal Adhesions as a Cellular Mechanism for Convergence between Integrins and G Protein-coupled Receptor Signaling Cascades
J. Biol. Chem. 2000 275: 32736-32746. Published as JBC Papers in Press 10.1074/jbc.M004200200 [Abstract] [Full Text] [PDF]  

Yoshiyuki Mochida, Kohsuke Takeda, Masao Saitoh, Hideki Nishitoh, Teruo Amagasa, Jun Ninomiya-Tsuji, Kunihiro Matsumoto, and Hidenori Ichijo

ASK1 Inhibits Interleukin-1-induced NF-B Activity through Disruption of TRAF6-TAK1 Interaction
J. Biol. Chem. 2000 275: 32747-32752. Published as JBC Papers in Press 10.1074/jbc.M003042200 [Abstract] [Full Text] [PDF]  

Matteo Landriscina, Igor Prudovsky, Carla Mouta Carreira, Raffaella Soldi, Francesca Tarantini, and Thomas Maciag

Amlexanox Reversibly Inhibits Cell Migration and Proliferation and Induces the Src-dependent Disassembly of Actin Stress Fibers in Vitro
J. Biol. Chem. 2000 275: 32753-32762. Published as JBC Papers in Press 10.1074/jbc.M002336200 [Abstract] [Full Text] [PDF]  

Jes K. Klarlund, William Tsiaras, John J. Holik, Anil Chawla, and Michael P. Czech

Distinct Polyphosphoinositide Binding Selectivities for Pleckstrin Homology Domains of GRP1-like Proteins Based on Diglycine Versus Triglycine Motifs
J. Biol. Chem. 2000 275: 32816-32821. Published as JBC Papers in Press 10.1074/jbc.M002435200 [Abstract] [Full Text] [PDF]  

Jormay Lim, Esther Sook Miin Wong, Siew Hwa Ong, Permeen Yusoff, Boon Chuan Low, and Graeme R. Guy

Sprouty Proteins Are Targeted to Membrane Ruffles upon Growth Factor Receptor Tyrosine Kinase Activation. IDENTIFICATION OF A NOVEL TRANSLOCATION DOMAIN
J. Biol. Chem. 2000 275: 32837-32845. Published as JBC Papers in Press 10.1074/jbc.M002156200 [Abstract] [Full Text] [PDF]  

Koichi Kokame, Kishan Lal Agarwala, Hisao Kato, and Toshiyuki Miyata

Herp, a New Ubiquitin-like Membrane Protein Induced by Endoplasmic Reticulum Stress
J. Biol. Chem. 2000 275: 32846-32853. Published as JBC Papers in Press 10.1074/jbc.M002063200 [Abstract] [Full Text] [PDF]  

Ikuo Sakamoto, Shosei Kishida, Akimasa Fukui, Michiko Kishida, Hideki Yamamoto, Shin-ichiro Hino, Tatsuo Michiue, Shinji Takada, Makoto Asashima, and Akira Kikuchi

A Novel -Catenin-binding Protein Inhibits -Catenin-dependent Tcf Activation and Axis Formation
J. Biol. Chem. 2000 275: 32871-32878. Published as JBC Papers in Press 10.1074/jbc.M004089200 [Abstract] [Full Text] [PDF]  

Isao Matsuura, Vladimir A. Bondarenko, Tomoko Maeda, Shu Kachi, Matsuyo Yamazaki, Jiro Usukura, Fumio Hayashi, and Akio Yamazaki

Phosphorylation by Cyclin-dependent Protein Kinase 5 of the Regulatory Subunit of Retinal cGMP Phosphodiesterase. I. IDENTIFICATION OF THE KINASE AND ITS ROLE IN THE TURNOFF OF PHOSPHODIESTERASE IN VITRO
J. Biol. Chem. 2000 275: 32950-32957. Published as JBC Papers in Press 10.1074/jbc.M000702200 [Abstract] [Full Text] [PDF]  

Fumio Hayashi, Isao Matsuura, Shu Kachi, Tomoko Maeda, Maki Yamamoto, Yuka Fujii, Han Liu, Matsuyo Yamazaki, Jiro Usukura, and Akio Yamazaki

Phosphorylation by Cyclin-dependent Protein Kinase 5 of the Regulatory Subunit of Retinal cGMP Phosphodiesterase. II. ITS ROLE IN THE TURNOFF OF PHOSPHODIESTERASE IN VIVO
J. Biol. Chem. 2000 275: 32958-32965. Published as JBC Papers in Press 10.1074/jbc.M000703200 [Abstract] [Full Text] [PDF]  

Ramesh R. Bhatt and James E. Ferrell, Jr.

Cloning and Characterization of Xenopus Rsk2, the Predominant p90 Rsk Isozyme in Oocytes and Eggs
J. Biol. Chem. 2000 275: 32983-32990. Published as JBC Papers in Press 10.1074/jbc.M006386200 [Abstract] [Full Text] [PDF]  

Sylvie Pasco, Jean-Claude Monboisse, and Nelly Kieffer

The 3(IV)185-206 Peptide from Noncollagenous Domain 1 of Type IV Collagen Interacts with a Novel Binding Site on the ₃ Subunit of Integrin _v3 and Stimulates Focal Adhesion Kinase and Phosphatidylinositol 3-Kinase Phosphorylation
J. Biol. Chem. 2000 275: 32999-33007. Published as JBC Papers in Press 10.1074/jbc.M005235200 [Abstract] [Full Text] [PDF]  

Mayya Meriane, Sophie Mary, Franck Comunale, Emmanuel Vignal, Philippe Fort, and Cécile Gauthier-Rouvière

Cdc42Hs and Rac1 GTPases Induce the Collapse of the Vimentin Intermediate Filament Network
J. Biol. Chem. 2000 275: 33046-33052. Published as JBC Papers in Press 10.1074/jbc.M001566200 [Abstract] [Full Text] [PDF]  

Scott P. Commins, Patricia M. Watson, Nancy Levin, Rudolph J. Beiler, and Thomas W. Gettys

Central Leptin Regulates the UCP1 and ob Genes in Brown and White Adipose Tissue via Different -Adrenoceptor Subtypes
J. Biol. Chem. 2000 275: 33059-33067. Published as JBC Papers in Press 10.1074/jbc.M006328200 [Abstract] [Full Text] [PDF]  

Jane Wong, Masamichi Ishiai, Tomohiro Kurosaki, and Andrew C. Chan

Functional Complementation of BLNK by SLP-76 and LAT Linker Proteins
J. Biol. Chem. 2000 275: 33116-33122. Published as JBC Papers in Press 10.1074/jbc.M004467200 [Abstract] [Full Text] [PDF]  

Jian Du, Yazan M. Alsayed, Feng Xin, Steven J. Ackerman, and Leonidas C. Platanias

Engagement of the CrkL Adapter in Interleukin-5 Signaling in Eosinophils
J. Biol. Chem. 2000 275: 33167-33175. Published as JBC Papers in Press 10.1074/jbc.M003655200 [Abstract] [Full Text] [PDF]  

Molecular Basis Of Cell and Developmental Biology:

Alan G. Ridgeway, Helen Petropoulos, Sharon Wilton, and Ilona S. Skerjanc

Wnt Signaling Regulates the Function of MyoD and Myogenin
J. Biol. Chem. 2000 275: 32398-32405. Published as JBC Papers in Press 10.1074/jbc.M004349200 [Abstract] [Full Text] [PDF]  

John D. Robertson, Vladimir Gogvadze, Boris Zhivotovsky, and Sten Orrenius

Distinct Pathways for Stimulation of Cytochrome c Release by Etoposide
J. Biol. Chem. 2000 275: 32438-32443. Published as JBC Papers in Press 10.1074/jbc.C000518200 [Abstract] [Full Text] [PDF]  

Cécile Bouton and Bruce Demple

Nitric Oxide-inducible Expression of Heme Oxygenase-1 in Human Cells. TRANSLATION-INDEPENDENT STABILIZATION OF THE mRNA AND EVIDENCE FOR DIRECT ACTION OF NITRIC OXIDE
J. Biol. Chem. 2000 275: 32688-32693. Published as JBC Papers in Press 10.1074/jbc.275.42.32688 [Abstract] [Full Text] [PDF]  

Sharon H. Tynan, Aruna Purohit, Stephen J. Doxsey, and Richard B. Vallee

Light Intermediate Chain 1 Defines a Functional Subfraction of Cytoplasmic Dynein Which Binds to Pericentrin
J. Biol. Chem. 2000 275: 32763-32768. Published as JBC Papers in Press 10.1074/jbc.M001536200 [Abstract] [Full Text] [PDF]  

Sharon H. Tynan, Melissa A. Gee, and Richard B. Vallee

Distinct but Overlapping Sites within the Cytoplasmic Dynein Heavy Chain for Dimerization and for Intermediate Chain and Light Intermediate Chain Binding
J. Biol. Chem. 2000 275: 32769-32774. Published as JBC Papers in Press 10.1074/jbc.M001537200 [Abstract] [Full Text] [PDF]  

Sanna Lehtonen, Ari Ora, Vesa M. Olkkonen, Lin Geng, Marino Zerial, Stefan Somlo, and Eero Lehtonen

In Vivo Interaction of the Adapter Protein CD2-associated Protein with the Type 2 Polycystic Kidney Disease Protein, Polycystin-2
J. Biol. Chem. 2000 275: 32888-32893. Published as JBC Papers in Press 10.1074/jbc.M006624200 [Abstract] [Full Text] [PDF]  

Nelson W. Chong, Marianne Bernard, and David C. Klein

Characterization of the Chicken Serotonin N-Acetyltransferase Gene. ACTIVATION VIA CLOCK GENE HETERODIMER/E BOX INTERACTION
J. Biol. Chem. 2000 275: 32991-32998. Published as JBC Papers in Press 10.1074/jbc.M005671200 [Abstract] [Full Text] [PDF]  

Additions and Corrections:

Thomas Eitinger, Olaf Degen, Ute Böhnke, and Marion Müller

Nic1p, a relative of bacterial transition metal permeases in Schizosaccharomyces pombe, provides nickel ion for urease biosynthesis.
J. Biol. Chem. 2000 275: 33184. [Full Text] [PDF]  

Jean-Baptiste Boulé, François Rougeon, and Catherine Papanicolaou

Comparison of the two murine terminal deoxynucleo- tidyltransferase isoforms. A 20-amino acid insertion in the highly conserved carboxyl-terminal region modifies the thermosensitivity but not the catalytic activity.
J. Biol. Chem. 2000 275: 33184. [Full Text] [PDF]  

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