Minireviews:

Bik K. Tye and Sara Sawyer

The Hexameric Eukaryotic MCM Helicase: Building Symmetry from Nonidentical Parts
J. Biol. Chem. 2000 275: 34833-34836. Published as JBC Papers in Press 10.1074/jbc.R000018200 [Full Text] [PDF]  

Accelerated Publications:

Nina Korsisaari and Tomi P. Mäkelä

Interactions of Cdk7 and Kin28 with Hint/PKCI-1 and Hnt1 Histidine Triad Proteins
J. Biol. Chem. 2000 275: 34837-34840. Published as JBC Papers in Press 10.1074/jbc.C000505200 [Abstract] [Full Text] [PDF]  

Behrous Davani, Akhtar Khan, Malin Hult, Eva Mårtensson, Sam Okret, Suad Efendic, Hans Jörnvall, and Udo C. T. Oppermann

Type 1 11-Hydroxysteroid Dehydrogenase Mediates Glucocorticoid Activation and Insulin Release in Pancreatic Islets
J. Biol. Chem. 2000 275: 34841-34844. Published as JBC Papers in Press 10.1074/jbc.C000600200 [Abstract] [Full Text] [PDF]  

Hieronim Jakubowski

Amino Acid Selectivity in the Aminoacylation of Coenzyme A and RNA Minihelices by Aminoacyl-tRNA Synthetases
J. Biol. Chem. 2000 275: 34845-34848. Published as JBC Papers in Press 10.1074/jbc.C000577200 [Abstract] [Full Text] [PDF]  

Hagar Lock and Miguel A. Valverde

Contribution of the IsK (MinK) Potassium Channel Subunit to Regulatory Volume Decrease in Murine Tracheal Epithelial Cells
J. Biol. Chem. 2000 275: 34849-34852. Published as JBC Papers in Press 10.1074/jbc.C000633200 [Abstract] [Full Text] [PDF]  

DNA: Replication Repair and Recombination:

Yoshimichi Nakatsu, Hiroshi Asahina, Elisabetta Citterio, Suzanne Rademakers, Wim Vermeulen, Shinya Kamiuchi, Jing-Ping Yeo, Min-Cheh Khaw, Masafumi Saijo, Naohiko Kodo, Toshiro Matsuda, Jan H. J. Hoeijmakers, and Kiyoji Tanaka

XAB2, a Novel Tetratricopeptide Repeat Protein Involved in Transcription-coupled DNA Repair and Transcription
J. Biol. Chem. 2000 275: 34931-34937. Published as JBC Papers in Press 10.1074/jbc.M004936200 [Abstract] [Full Text] [PDF]  

Suman K. Dhar and Anindya Dutta

Identification and Characterization of the Human ORC6 Homolog
J. Biol. Chem. 2000 275: 34983-34988. Published as JBC Papers in Press 10.1074/jbc.M006069200 [Abstract] [Full Text] [PDF]  

Makoto Kihara, Wataru Nakai, Satoshi Asano, Akiko Suzuki, Kunio Kitada, Yasuo Kawasaki, Leland H. Johnston, and Akio Sugino

Characterization of the Yeast Cdc7p/Dbf4p Complex Purified from Insect Cells. ITS PROTEIN KINASE ACTIVITY IS REGULATED BY Rad53p
J. Biol. Chem. 2000 275: 35051-35062. Published as JBC Papers in Press 10.1074/jbc.M003491200 [Abstract] [Full Text] [PDF]  

Kelly C. Thome, Suman K. Dhar, David G. Quintana, Laurie Delmolino, Aliakbar Shahsafaei, and Anindya Dutta

Subsets of Human Origin Recognition Complex (ORC) Subunits Are Expressed in Non-proliferating Cells and Associate with Non-ORC Proteins
J. Biol. Chem. 2000 275: 35233-35241. Published as JBC Papers in Press 10.1074/jbc.M005765200 [Abstract] [Full Text] [PDF]  

Aranzazu Gual, Ana G. Camacho, and Juan C. Alonso

Functional Analysis of the Terminase Large Subunit, G2P, of Bacillus subtilis Bacteriophage SPP1
J. Biol. Chem. 2000 275: 35311-35319. Published as JBC Papers in Press 10.1074/jbc.M004309200 [Abstract] [Full Text] [PDF]  

Qiu-Mei Zhang, Izumi Miyabe, Yukiko Matsumoto, Katsuhito Kino, Hiroshi Sugiyama, and Shuji Yonei

Identification of Repair Enzymes for 5-Formyluracil in DNA. Nth, Nei, AND MutM PROTEINS OF ESCHERICHIA COLI
J. Biol. Chem. 2000 275: 35471-35477. Published as JBC Papers in Press 10.1074/jbc.M006125200 [Abstract] [Full Text] [PDF]  

Christian Keller and Torsten Krude

Requirement of Cyclin/Cdk2 and Protein Phosphatase 1 Activity for Chromatin Assembly Factor 1-dependent Chromatin Assembly during DNA Synthesis
J. Biol. Chem. 2000 275: 35512-35521. Published as JBC Papers in Press 10.1074/jbc.M003073200 [Abstract] [Full Text] [PDF]  

Woo Jae Kim, Suman Lee, Min Sung Park, Yeun Kyu Jang, Jae Bum Kim, and Sang Dai Park

Rad22 Protein, a Rad52 Homologue in Schizosaccharomyces pombe, Binds to DNA Double-strand Breaks
J. Biol. Chem. 2000 275: 35607-35611. Published as JBC Papers in Press 10.1074/jbc.M007060200 [Abstract] [Full Text] [PDF]  

Genes: Structure and Regulation:

Martine Pastorcic and Hriday K. Das

Regulation of Transcription of the Human Presenilin-1 Gene by Ets Transcription Factors and the p53 Protooncogene
J. Biol. Chem. 2000 275: 34938-34945. Published as JBC Papers in Press 10.1074/jbc.M005411200 [Abstract] [Full Text] [PDF]  

Joern Boeke, Ole Ammerpohl, Simone Kegel, Udo Moehren, and Rainer Renkawitz

The Minimal Repression Domain of MBD2b Overlaps with the Methyl-CpG-binding Domain and Binds Directly to Sin3A
J. Biol. Chem. 2000 275: 34963-34967. Published as JBC Papers in Press 10.1074/jbc.M005929200 [Abstract] [Full Text] [PDF]  

Wei Lu, Ronald Peterson, Atreyi Dasgupta, and William M. Scovell

Influence of HMG-1 and Adenovirus Oncoprotein E1A on Early Stages of Transcriptional Preinitiation Complex Assembly
J. Biol. Chem. 2000 275: 35006-35012. Published as JBC Papers in Press 10.1074/jbc.M004735200 [Abstract] [Full Text] [PDF]  

Elena Tolkunova, Hyejeong Park, Jun Xia, Michael P. King, and Edgar Davidson

The Human Lysyl-tRNA Synthetase Gene Encodes Both the Cytoplasmic and Mitochondrial Enzymes by Means of an Unusual Alternative Splicing of the Primary Transcript
J. Biol. Chem. 2000 275: 35063-35069. Published as JBC Papers in Press 10.1074/jbc.M006265200 [Abstract] [Full Text] [PDF]  

Zhijiang Yan and Anton M. Jetten

Characterization of the Repressor Function of the Nuclear Orphan Receptor Retinoid Receptor-related Testis-associated Receptor/Germ Cell Nuclear Factor
J. Biol. Chem. 2000 275: 35077-35085. Published as JBC Papers in Press 10.1074/jbc.M005566200 [Abstract] [Full Text] [PDF]  

Manju Sharma, Mark Zarnegar, Xiaoyu Li, Bing Lim, and Zijie Sun

Androgen Receptor Interacts with a Novel MYST Protein, HBO1
J. Biol. Chem. 2000 275: 35200-35208. Published as JBC Papers in Press 10.1074/jbc.M004838200 [Abstract] [Full Text] [PDF]  

Bassel E. Sawaya, Kamel Khalili, Jennifer Gordon, Ran Taube, and Shohreh Amini

Cooperative Interaction between HIV-1 Regulatory Proteins Tat and Vpr Modulates Transcription of the Viral Genome
J. Biol. Chem. 2000 275: 35209-35214. Published as JBC Papers in Press 10.1074/jbc.M005197200 [Abstract] [Full Text] [PDF]  

Maria A. Schumacher, Richard H. Goodman, and Richard G. Brennan

The Structure of a CREB bZIP·Somatostatin CRE Complex Reveals the Basis for Selective Dimerization and Divalent Cation-enhanced DNA Binding
J. Biol. Chem. 2000 275: 35242-35247. Published as JBC Papers in Press 10.1074/jbc.M007293200 [Abstract] [Full Text] [PDF]  

Dmitry Guschin, Theresa M. Geiman, Nobuaki Kikyo, David J. Tremethick, Alan P. Wolffe, and Paul A. Wade

Multiple ISWI ATPase Complexes from Xenopus laevis. FUNCTIONAL CONSERVATION OF AN ACF/CHRAC HOMOLOG
J. Biol. Chem. 2000 275: 35248-35255. Published as JBC Papers in Press 10.1074/jbc.M006041200 [Abstract] [Full Text] [PDF]  

Nathalie Matter, Manuela Marx, Susanne Weg-Remers, Helmut Ponta, Peter Herrlich, and Harald König

Heterogeneous Ribonucleoprotein A1 Is Part of an Exon-specific Splice-silencing Complex Controlled by Oncogenic Signaling Pathways
J. Biol. Chem. 2000 275: 35353-35360. Published as JBC Papers in Press 10.1074/jbc.M004692200 [Abstract] [Full Text] [PDF]  

Sally A. Hemming, David B. Jansma, Pascale F. Macgregor, Andrew Goryachev, James D. Friesen, and Aled M. Edwards

RNA Polymerase II Subunit Rpb9 Regulates Transcription Elongation in Vivo
J. Biol. Chem. 2000 275: 35506-35511. Published as JBC Papers in Press 10.1074/jbc.M004721200 [Abstract] [Full Text] [PDF]  

Kangjian Wu, Shi-Wen Jiang, Muthusamy Thangaraju, Guojun Wu, and Fergus J. Couch

Induction of the BRCA2 Promoter by Nuclear Factor-B
J. Biol. Chem. 2000 275: 35548-35556. Published as JBC Papers in Press 10.1074/jbc.M004390200 [Abstract] [Full Text] [PDF]  

RNA: Structure Metabolism and Catalysis:

Toshio Uchiumi, Takaomi Nomura, Tomomi Shimizu, Yuto Katakai, Kazuei Mita, Yoshiko Koike, Masao Nakagaki, Hideharu Taira, and Akira Hachimori

A Covariant Change of the Two Highly Conserved Bases in the GTPase-associated Center of 28 S rRNA in Silkworms and Other Moths
J. Biol. Chem. 2000 275: 35116-35121. Published as JBC Papers in Press 10.1074/jbc.M004596200 [Abstract] [Full Text] [PDF]  

Heidi S. Hummel, R. Dean Gillespie, and John Swindle

Mutational Analysis of 3' Splice Site Selection during trans-Splicing
J. Biol. Chem. 2000 275: 35522-35531. Published as JBC Papers in Press 10.1074/jbc.M002424200 [Abstract] [Full Text] [PDF]  

Martin Horlitz and Petra Klaff

Gene-specific trans-Regulatory Functions of Magnesium for Chloroplast mRNA Stability in Higher Plants
J. Biol. Chem. 2000 275: 35638-35645. Published as JBC Papers in Press 10.1074/jbc.M005622200 [Abstract] [Full Text] [PDF]  

Protein Synthesis Post-Translation Modification and Degradation:

Xiaoying Wang, Susan C. Moore, Mario Laszckzak, and Juan Ausió

Acetylation Increases the -Helical Content of the Histone Tails of the Nucleosome
J. Biol. Chem. 2000 275: 35013-35020. Published as JBC Papers in Press 10.1074/jbc.M004998200 [Abstract] [Full Text] [PDF]  

Oriol Casanovas, Francesc Miró, Josep Maria Estanyol, Emili Itarte, Neus Agell, and Oriol Bachs

Osmotic Stress Regulates the Stability of Cyclin D1 in a p38^SAPK2-dependent Manner
J. Biol. Chem. 2000 275: 35091-35097. Published as JBC Papers in Press 10.1074/jbc.M006324200 [Abstract] [Full Text] [PDF]  

Qun Zhou, Zaroui K. Melkoumian, Ann Lucktong, Mariko Moniwa, James R. Davie, and Jeannine S. Strobl

Rapid Induction of Histone Hyperacetylation and Cellular Differentiation in Human Breast Tumor Cell Lines following Degradation of Histone Deacetylase-1
J. Biol. Chem. 2000 275: 35256-35263. Published as JBC Papers in Press 10.1074/jbc.M003106200 [Abstract] [Full Text] [PDF]  

Protein Structure and Folding:

Ifat Sher, Tamar Lang, Sharon Lubinsky-Mink, Jonathan Kuhn, Noam Adir, Shivani Chatterjee, Dietmar Schomburg, and Dina Ron

Identification of Residues Important Both for Primary Receptor Binding and Specificity in Fibroblast Growth Factor-7
J. Biol. Chem. 2000 275: 34881-34886. Published as JBC Papers in Press 10.1074/jbc.M003293200 [Abstract] [Full Text] [PDF]  

Blair J. N. Leonard, Bryan J. Clarke, Sampath Sridhara, Robert Kelley, Fred A. Ofosu, and Morris A. Blajchman

Activation and Active Site Occupation Alter Conformation in the Region of the First Epidermal Growth Factor-like Domain of Human Factor VII
J. Biol. Chem. 2000 275: 34894-34900. Published as JBC Papers in Press 10.1074/jbc.M001166200 [Abstract] [Full Text] [PDF]  

Bing Chen, Genfa Zhou, Mikyung Kim, Yasmin Chishti, Rebecca E. Hussey, Barry Ely, John J. Skehel, Ellis L. Reinherz, Stephen C. Harrison, and Don C. Wiley

Expression, Purification, and Characterization of gp160e, the Soluble, Trimeric Ectodomain of the Simian Immunodeficiency Virus Envelope Glycoprotein, gp160
J. Biol. Chem. 2000 275: 34946-34953. Published as JBC Papers in Press 10.1074/jbc.M004905200 [Abstract] [Full Text] [PDF]  

Dharmaraj Samuel, Thallampuranam Krishnaswamy Suresh Kumar, Thiagarajan Srimathi, Hui-chu Hsieh, and Chin Yu

Identification and Characterization of an Equilibrium Intermediate in the Unfolding Pathway of an All -Barrel Protein
J. Biol. Chem. 2000 275: 34968-34975. Published as JBC Papers in Press 10.1074/jbc.M005147200 [Abstract] [Full Text] [PDF]  

Christopher S. Hayes, Zheng-Yu Peng, and Peter Setlow

Equilibrium and Kinetic Binding Interactions between DNA and a Group of Novel, Nonspecific DNA-binding Proteins from Spores of Bacillus and Clostridium Species
J. Biol. Chem. 2000 275: 35040-35050. Published as JBC Papers in Press 10.1074/jbc.M005669200 [Abstract] [Full Text] [PDF]  

Miriam S. Domowicz, Edward W. Pirok, III, Todd E. Novak, and Nancy B. Schwartz

Role of the C-terminal G3 Domain in Sorting and Secretion of Aggrecan Core Protein and Ubiquitin-mediated Degradation of Accumulated Mutant Precursors
J. Biol. Chem. 2000 275: 35098-35105. [Abstract] [Full Text] [PDF]  

Joyce R. Pearlstone, Murali Chandra, Martha M. Sorenson, and Lawrence B. Smillie

Biological Function and Site II Ca²⁺-induced Opening of the Regulatory Domain of Skeletal Troponin C Are Impaired by Invariant Site I or II Glu Mutations
J. Biol. Chem. 2000 275: 35106-35115. Published as JBC Papers in Press 10.1074/jbc.M001000200 [Abstract] [Full Text] [PDF]  

Sanjeev Kumar, Jatinderpal Kalsi, Chelliah T. Ravirajan, Anisur Rahman, Dee Athwal, David S. Latchman, David A. Isenberg, and Laurence H. Pearl

Molecular Cloning and Expression of the Fabs of Human Autoantibodies in Escherichia coli. DETERMINATION OF THE HEAVY OR LIGHT CHAIN CONTRIBUTION TO THE ANTI-DNA/-CARDIOLIPIN ACTIVITY OF THE Fab
J. Biol. Chem. 2000 275: 35129-35136. Published as JBC Papers in Press 10.1074/jbc.M001976200 [Abstract] [Full Text] [PDF]  

Erika E. Büllesbach and Christian Schwabe

The Relaxin Receptor-binding Site Geometry Suggests a Novel Gripping Mode of Interaction
J. Biol. Chem. 2000 275: 35276-35280. Published as JBC Papers in Press 10.1074/jbc.M005728200 [Abstract] [Full Text] [PDF]  

Hiroko Kawasaki, Takeru Nose, Tatsushi Muta, Sadaaki Iwanaga, Yasuyuki Shimohigashi, and Shun-ichiro Kawabata

Head-to-Tail Polymerization of Coagulin, a Clottable Protein of the Horseshoe Crab
J. Biol. Chem. 2000 275: 35297-35301. Published as JBC Papers in Press 10.1074/jbc.M006856200 [Abstract] [Full Text] [PDF]  

Jean Christophe Deloulme, Nicole Assard, Gaëlh Ouengue Mbele, Carole Mangin, Ryozo Kuwano, and Jacques Baudier

S100A6 and S100A11 Are Specific Targets of the Calcium- and Zinc-binding S100B Protein in Vivo
J. Biol. Chem. 2000 275: 35302-35310. Published as JBC Papers in Press 10.1074/jbc.M003943200 [Abstract] [Full Text] [PDF]  

Joel R. Hoskins, Soon-Young Kim, and Sue Wickner

Substrate Recognition by the ClpA Chaperone Component of ClpAP Protease
J. Biol. Chem. 2000 275: 35361-35367. Published as JBC Papers in Press 10.1074/jbc.M006288200 [Abstract] [Full Text] [PDF]  

Jun Xing, Willy Wriggers, Geraldine M. Jefferson, Richard Stein, Herbert C. Cheung, and Steven S. Rosenfeld

Kinesin Has Three Nucleotide-dependent Conformations. IMPLICATIONS FOR STRAIN-DEPENDENT RELEASE
J. Biol. Chem. 2000 275: 35413-35423. Published as JBC Papers in Press 10.1074/jbc.M004232200 [Abstract] [Full Text] [PDF]  

Easwari Kumaraswamy, Andrey Malykh, Konstantin V. Korotkov, Sergei Kozyavkin, Yajun Hu, So Yeon Kwon, Mohamed E. Moustafa, Bradley A. Carlson, Marla J. Berry, Byeong J. Lee, Dolph L. Hatfield, Alan M. Diamond, and Vadim N. Gladyshev

Structure-Expression Relationships of the 15-kDa Selenoprotein Gene. POSSIBLE ROLE OF THE PROTEIN IN CANCER ETIOLOGY
J. Biol. Chem. 2000 275: 35540-35547. Published as JBC Papers in Press 10.1074/jbc.M004014200 [Abstract] [Full Text] [PDF]  

Enzyme Catalysis and Regulation:

Tsuyoshi Egawa, Hideo Shimada, and Yuzuru Ishimura

Formation of Compound I in the Reaction of Native Myoglobins with Hydrogen Peroxide
J. Biol. Chem. 2000 275: 34858-34866. Published as JBC Papers in Press 10.1074/jbc.M004026200 [Abstract] [Full Text] [PDF]  

James E. Thompson, Stephen Fahnestock, Leonard Farrall, Der-Ing Liao, Barbara Valent, and Douglas B. Jordan

The Second Naphthol Reductase of Fungal Melanin Biosynthesis in Magnaporthe grisea. TETRAHYDROXYNAPHTHALENE REDUCTASE
J. Biol. Chem. 2000 275: 34867-34872. Published as JBC Papers in Press 10.1074/jbc.M006659200 [Abstract] [Full Text] [PDF]  

Carole Creuzenet, Melissa J. Schur, Jianjun Li, Warren W. Wakarchuk, and Joseph S. Lam

FlaA1, a New Bifunctional UDP-GlcNAc C₆ Dehydratase/ C₄ Reductase from Helicobacter pylori
J. Biol. Chem. 2000 275: 34873-34880. Published as JBC Papers in Press 10.1074/jbc.M006369200 [Abstract] [Full Text] [PDF]  

Werner Brabetz, Sven Müller-Loennies, and Helmut Brade

3-Deoxy-D-manno-oct-2-ulosonic Acid (Kdo) Transferase (WaaA) and Kdo Kinase (KdkA) of Haemophilus influenzae Are Both Required to Complement a waaA Knockout Mutation of Escherichia coli
J. Biol. Chem. 2000 275: 34954-34962. Published as JBC Papers in Press 10.1074/jbc.M005204200 [Abstract] [Full Text] [PDF]  

Alexandra Martins and Stewart Shuman

Mechanism of Phosphoanhydride Cleavage by Baculovirus Phosphatase
J. Biol. Chem. 2000 275: 35070-35076. Published as JBC Papers in Press 10.1074/jbc.M005748200 [Abstract] [Full Text] [PDF]  

Veronica V. Pollock and Michael J. Barber

Serine 121 Is an Essential Amino Acid for Biotin Sulfoxide Reductase Functionality
J. Biol. Chem. 2000 275: 35086-35090. Published as JBC Papers in Press 10.1074/jbc.M006872200 [Abstract] [Full Text] [PDF]  

Byung-Chun Yoo, Koh Aoki, Yu Xiang, Leslie R. Campbell, Richard J. Hull, Beatriz Xoconostle-Cázares, Jan Monzer, Jung-Youn Lee, Diane E. Ullman, and William J. Lucas

Characterization of Cucurbita maxima Phloem Serpin-1 (CmPS-1). A DEVELOPMENTALLY REGULATED ELASTASE INHIBITOR
J. Biol. Chem. 2000 275: 35122-35128. Published as JBC Papers in Press 10.1074/jbc.M006060200 [Abstract] [Full Text] [PDF]  

Martin Willemoës, Bjarne Hove-Jensen, and Sine Larsen

Steady State Kinetic Model for the Binding of Substrates and Allosteric Effectors to Escherichia coli Phosphoribosyl-diphosphate Synthase
J. Biol. Chem. 2000 275: 35408-35412. Published as JBC Papers in Press 10.1074/jbc.M006346200 [Abstract] [Full Text] [PDF]  

Paul D. Wagner and Ngoc-Diep Vu

Phosphorylation of Geranyl and Farnesyl Pyrophosphates by Nm23 Proteins/Nucleoside Diphosphate Kinases
J. Biol. Chem. 2000 275: 35570-35576. Published as JBC Papers in Press 10.1074/jbc.M006106200 [Abstract] [Full Text] [PDF]  

Bradley B. Brasher and Richard A. Van Etten

c-Abl Has High Intrinsic Tyrosine Kinase Activity That Is Stimulated by Mutation of the Src Homology 3 Domain and by Autophosphorylation at Two Distinct Regulatory Tyrosines
J. Biol. Chem. 2000 275: 35631-35637. Published as JBC Papers in Press 10.1074/jbc.M005401200 [Abstract] [Full Text] [PDF]  

Jae Rin Suh, Emia W. Oppenheim, Sameh Girgis, and Patrick J. Stover

Purification and Properties of a Folate-catabolizing Enzyme
J. Biol. Chem. 2000 275: 35646-35655. Published as JBC Papers in Press 10.1074/jbc.M005864200 [Abstract] [Full Text] [PDF]  

Metabolism and Bioenergetics:

Ayako Okado-Matsumoto and Irwin Fridovich

The Role of ,-Dicarbonyl Compounds in the Toxicity of Short Chain Sugars
J. Biol. Chem. 2000 275: 34853-34857. Published as JBC Papers in Press 10.1074/jbc.M005536200 [Abstract] [Full Text] [PDF]  

Johann M. Rohwer, Norman D. Meadow, Saul Roseman, Hans V. Westerhoff, and Pieter W. Postma

Understanding Glucose Transport by the Bacterial Phosphoenolpyruvate:Glycose Phosphotransferase System on the Basis of Kinetic Measurements in Vitro
J. Biol. Chem. 2000 275: 34909-34921. Published as JBC Papers in Press 10.1074/jbc.M002461200 [Abstract] [Full Text] [PDF]  

Michelle S. Jansen, George A. Cook, Shulan Song, and Edwards A. Park

Thyroid Hormone Regulates Carnitine Palmitoyltransferase I Gene Expression through Elements in the Promoter and First Intron
J. Biol. Chem. 2000 275: 34989-34997. Published as JBC Papers in Press 10.1074/jbc.M001752200 [Abstract] [Full Text] [PDF]  

Glycobiology and Extracellular Matrices:

Lawrence E. Goldfinger, Luohua Jiang, Susan B. Hopkinson, M. Sharon Stack, and Jonathan C. R. Jones

Spatial Regulation and Activity Modulation of Plasmin by High Affinity Binding to the G domain of the ₃ Subunit of Laminin-5
J. Biol. Chem. 2000 275: 34887-34893. Published as JBC Papers in Press 10.1074/jbc.M006652200 [Abstract] [Full Text] [PDF]  

Manoranjan Santra, Inge Eichstetter, and Renato V. Iozzo

An Anti-oncogenic Role for Decorin. DOWN-REGULATION OF ErbB2 LEADS TO GROWTH SUPPRESSION AND CYTODIFFERENTIATION OF MAMMARY CARCINOMA CELLS
J. Biol. Chem. 2000 275: 35153-35161. Published as JBC Papers in Press 10.1074/jbc.M006821200 [Abstract] [Full Text] [PDF]  

Jan F. Talts, Takako Sasaki, Nicolai Miosge, Walter Göhring, Karlheinz Mann, Richard Mayne, and Rupert Timpl

Structural and Functional Analysis of the Recombinant G Domain of the Laminin 4 Chain and Its Proteolytic Processing in Tissues
J. Biol. Chem. 2000 275: 35192-35199. Published as JBC Papers in Press 10.1074/jbc.M003261200 [Abstract] [Full Text] [PDF]  

Burgi Recheis, Andreas Osanger, Sabine Haubenwallner, Wolfgang J. Schneider, and Johannes Nimpf

Chicken Coagulation Factor XIIIA Is Produced by the Theca Externa and Stabilizes the Ovarian Follicular Wall
J. Biol. Chem. 2000 275: 35320-35327. Published as JBC Papers in Press 10.1074/jbc.M005025200 [Abstract] [Full Text] [PDF]  

Hiroto Kawashima, Mayumi Hirose, Jun Hirose, Daisuke Nagakubo, Anna H. K. Plaas, and Masayuki Miyasaka

Binding of a Large Chondroitin Sulfate/Dermatan Sulfate Proteoglycan, Versican, to L-selectin, P-selectin, and CD44
J. Biol. Chem. 2000 275: 35448-35456. Published as JBC Papers in Press 10.1074/jbc.M003387200 [Abstract] [Full Text] [PDF]  

Tristan Barbeyron, Gurvan Michel, Philippe Potin, Bernard Henrissat, and Bernard Kloareg

-Carrageenases Constitute a Novel Family of Glycoside Hydrolases, Unrelated to That of -Carrageenases
J. Biol. Chem. 2000 275: 35499-35505. Published as JBC Papers in Press 10.1074/jbc.M003404200 [Abstract] [Full Text] [PDF]  

Thorsten Kirsch, Gerald Harrison, Ellis E. Golub, and Hyun-Duck Nah

The Roles of Annexins and Types II and X Collagen in Matrix Vesicle-mediated Mineralization of Growth Plate Cartilage
J. Biol. Chem. 2000 275: 35577-35583. Published as JBC Papers in Press 10.1074/jbc.M005648200 [Abstract] [Full Text] [PDF]  

Lipids and Lipoproteins:

Steven J. Steinberg, Janine Morgenthaler, Ann K. Heinzer, Kirby D. Smith, and Paul A. Watkins

Very Long-chain Acyl-CoA Synthetases. HUMAN "BUBBLEGUM" REPRESENTS A NEW FAMILY OF PROTEINS CAPABLE OF ACTIVATING VERY LONG-CHAIN FATTY ACIDS
J. Biol. Chem. 2000 275: 35162-35169. Published as JBC Papers in Press 10.1074/jbc.M006403200 [Abstract] [Full Text] [PDF]  

Hee-Yong Kim, Mohammed Akbar, Audrey Lau, and Lisa Edsall

Inhibition of Neuronal Apoptosis by Docosahexaenoic Acid (22:6n-3). ROLE OF PHOSPHATIDYLSERINE IN ANTIAPOPTOTIC EFFECT
J. Biol. Chem. 2000 275: 35215-35223. Published as JBC Papers in Press 10.1074/jbc.M004446200 [Abstract] [Full Text] [PDF]  

Dajun Zhang, Wei Tang, Pin Mei Yao, Chingwen Yang, Boxun Xie, Suzanne Jackowski, and Ira Tabas

Macrophages Deficient in CTP:Phosphocholine Cytidylyltransferase- Are Viable under Normal Culture Conditions but Are Highly Susceptible to Free Cholesterol-induced Death. MOLECULAR GENETIC EVIDENCE THAT THE INDUCTION OF PHOSPHATIDYLCHOLINE BIOSYNTHESIS IN FREE CHOLESTEROL-LOADED MACROPHAGES IS AN ADAPTIVE RESPONSE
J. Biol. Chem. 2000 275: 35368-35376. Published as JBC Papers in Press 10.1074/jbc.M007099200 [Abstract] [Full Text] [PDF]  

Membrane Transport Structure Function and Biogenesis:

Sherif E. Gabriel, Mariya Makhlina, Elena Martsen, Emma J. Thomas, Mike I. Lethem, and Richard C. Boucher

Permeabilization via the P2X₇ Purinoreceptor Reveals the Presence of a Ca²⁺-activated Cl Conductance in the Apical Membrane of Murine Tracheal Epithelial Cells
J. Biol. Chem. 2000 275: 35028-35033. Published as JBC Papers in Press 10.1074/jbc.M004953200 [Abstract] [Full Text] [PDF]  

Isabelle Staropoli, Chantal Chanel, Marc Girard, and Ralf Altmeyer

Processing, Stability, and Receptor Binding Properties of Oligomeric Envelope Glycoprotein from a Primary HIV-1 Isolate
J. Biol. Chem. 2000 275: 35137-35145. Published as JBC Papers in Press 10.1074/jbc.M003868200 [Abstract] [Full Text] [PDF]  

Carl M. Hurt, Felix Y. Feng, and Brian Kobilka

Cell-type Specific Targeting of the _2c-Adrenoceptor. EVIDENCE FOR THE ORGANIZATION OF RECEPTOR MICRODOMAINS DURING NEURONAL DIFFERENTIATION OF PC12 CELLS
J. Biol. Chem. 2000 275: 35424-35431. Published as JBC Papers in Press 10.1074/jbc.M006241200 [Abstract] [Full Text] [PDF]  

Pamela D. Arora, Morris F. Manolson, Gregory P. Downey, Jaro Sodek, and Christopher A. G. McCulloch

A Novel Model System for Characterization of Phagosomal Maturation, Acidification, and Intracellular Collagen Degradation in Fibroblasts
J. Biol. Chem. 2000 275: 35432-35441. Published as JBC Papers in Press 10.1074/jbc.M003221200 [Abstract] [Full Text] [PDF]  

Chang-Zheng Wang, Hideki Yano, Kazuaki Nagashima, and Susumu Seino

The Na⁺-driven Cl/HCO₃ Exchanger. CLONING, TISSUE DISTRIBUTION, AND FUNCTIONAL CHARACTERIZATION
J. Biol. Chem. 2000 275: 35486-35490. Published as JBC Papers in Press 10.1074/jbc.C000456200 [Abstract] [Full Text] [PDF] Supplemental Data  

Xiaotian Zhong, Rajeev Malhotra, and Guido Guidotti

Regulation of Yeast Ectoapyrase Ynd1p Activity by Activator Subunit Vma13p of Vacuolar H⁺-ATPase
J. Biol. Chem. 2000 275: 35592-35599. Published as JBC Papers in Press 10.1074/jbc.M006932200 [Abstract] [Full Text] [PDF]  

Mechanisms Of Signal Transduction:

John F. Rebhun, Ariel F. Castro, and Lawrence A. Quilliam

Identification of Guanine Nucleotide Exchange Factors (GEFs) for the Rap1 GTPase. REGULATION OF MR-GEF BY M-Ras-GTP INTERACTION
J. Biol. Chem. 2000 275: 34901-34908. Published as JBC Papers in Press 10.1074/jbc.M005327200 [Abstract] [Full Text] [PDF]  

Matthew Peirce and Henry Metzger

Detergent-resistant Microdomains Offer No Refuge for Proteins Phosphorylated by the IgE Receptor
J. Biol. Chem. 2000 275: 34976-34982. Published as JBC Papers in Press 10.1074/jbc.M005819200 [Abstract] [Full Text] [PDF]  

Hiroki Tabata, Takako Matsuoka, Fumio Endo, Yasuharu Nishimura, and Sho Matsushita

Ligation of HLA-DR Molecules on B Cells Induces Enhanced Expression of IgM Heavy Chain Genes in Association with Syk Activation
J. Biol. Chem. 2000 275: 34998-35005. Published as JBC Papers in Press 10.1074/jbc.M002089200 [Abstract] [Full Text] [PDF]  

Jonelle K. Drugan, Kelley Rogers-Graham, Tona Gilmer, Sharon Campbell, and Geoffrey J. Clark

The Ras/p120 GTPase-activating Protein (GAP) Interaction Is Regulated by the p120 GAP Pleckstrin Homology Domain
J. Biol. Chem. 2000 275: 35021-35027. Published as JBC Papers in Press 10.1074/jbc.M004386200 [Abstract] [Full Text] [PDF]  

Noel M. Fong, Timothy C. Jensen, Ami S. Shah, Nita N. Parekh, Alan R. Saltiel, and Matthew J. Brady

Identification of Binding Sites on Protein Targeting to Glycogen for Enzymes of Glycogen Metabolism
J. Biol. Chem. 2000 275: 35034-35039. Published as JBC Papers in Press 10.1074/jbc.M005541200 [Abstract] [Full Text] [PDF]  

Poopak Banky, Marceen G. Newlon, Melinda Roy, Siv Garrod, Susan S. Taylor, and Patricia A. Jennings

Isoform-specific Differences between the Type I and II Cyclic AMP-dependent Protein Kinase Anchoring Domains Revealed by Solution NMR
J. Biol. Chem. 2000 275: 35146-35152. Published as JBC Papers in Press 10.1074/jbc.M003961200 [Abstract] [Full Text] [PDF]  

Makoto Miyagishi, Ryouji Fujii, Mitsutoki Hatta, Eisaku Yoshida, Natsumi Araya, Akira Nagafuchi, Satoru Ishihara, Toshihiro Nakajima, and Akiyoshi Fukamizu

Regulation of Lef-mediated Transcription and p53-dependent Pathway by Associating -Catenin with CBP/p300
J. Biol. Chem. 2000 275: 35170-35175. Published as JBC Papers in Press 10.1074/jbc.C000258200 [Abstract] [Full Text] [PDF]  

Ralf B. Nehring, Hiroshi P. M. Horikawa, Oussama El Far, Matthias Kneussel, Johann Helmut Brandstätter, Stefan Stamm, Erhard Wischmeyer, Heinrich Betz, and Andreas Karschin

The Metabotropic GABA_B Receptor Directly Interacts with the Activating Transcription Factor 4
J. Biol. Chem. 2000 275: 35185-35191. Published as JBC Papers in Press 10.1074/jbc.M002727200 [Abstract] [Full Text] [PDF]  

Yue Zhang, Olga Redina, Yelena M. Altshuller, Masakazu Yamazaki, Joe Ramos, Herve Chneiweiss, Yasunori Kanaho, and Michael A. Frohman

Regulation of Expression of Phospholipase D1 and D2 by PEA-15, a Novel Protein That Interacts with Them
J. Biol. Chem. 2000 275: 35224-35232. Published as JBC Papers in Press 10.1074/jbc.M003329200 [Abstract] [Full Text] [PDF]  

Jean-Marie Dukuzumuremyi, Roland Rosqvist, Bengt Hallberg, Bo Åkerström, Hans Wolf-Watz, and Kurt Schesser

The Yersinia Protein Kinase A Is a Host Factor Inducible RhoA/Rac-binding Virulence Factor
J. Biol. Chem. 2000 275: 35281-35290. Published as JBC Papers in Press 10.1074/jbc.M003009200 [Abstract] [Full Text] [PDF]  

Michael J. McManus, Julie L. Boerner, Andrew J. Danielsen, Ze Wang, Fumio Matsumura, and Nita J. Maihle

An Oncogenic Epidermal Growth Factor Receptor Signals via a p21-activated Kinase-Caldesmon-Myosin Phosphotyrosine Complex
J. Biol. Chem. 2000 275: 35328-35334. Published as JBC Papers in Press 10.1074/jbc.M005399200 [Abstract] [Full Text] [PDF]  

Richard J. Lewis, Katherine J. Nielsen, David J. Craik, Marion L. Loughnan, Denise A. Adams, Iain A. Sharpe, Tudor Luchian, David J. Adams, Trudy Bond, Linda Thomas, Alun Jones, Jodi-Lea Matheson, Roger Drinkwater, Peter R. Andrews, and Paul F. Alewood

Novel -Conotoxins from Conus catus Discriminate among Neuronal Calcium Channel Subtypes
J. Biol. Chem. 2000 275: 35335-35344. Published as JBC Papers in Press 10.1074/jbc.M002252200 [Abstract] [Full Text] [PDF]  

Bernardo Yusta, Robin P. Boushey, and Daniel J. Drucker

The Glucagon-like Peptide-2 Receptor Mediates Direct Inhibition of Cellular Apoptosis via a cAMP-dependent Protein Kinase-independent Pathway
J. Biol. Chem. 2000 275: 35345-35352. Published as JBC Papers in Press 10.1074/jbc.M005510200 [Abstract] [Full Text] [PDF]  

Michitaka Ozaki, Shailesh S. Deshpande, Piamsook Angkeow, Seiichi Suzuki, and Kaikobad Irani

Rac1 Regulates Stress-induced, Redox-dependent Heat Shock Factor Activation
J. Biol. Chem. 2000 275: 35377-35383. Published as JBC Papers in Press 10.1074/jbc.M005287200 [Abstract] [Full Text] [PDF]  

Adi Geva, Tracey B. Lassere, Olivier Lichtarge, Sonia K. Pollitt, and Thomas J. Baranski

Genetic Mapping of the Human C5a Receptor. IDENTIFICATION OF TRANSMEMBRANE AMINO ACIDS CRITICAL FOR RECEPTOR FUNCTION
J. Biol. Chem. 2000 275: 35393-35401. Published as JBC Papers in Press 10.1074/jbc.M005602200 [Abstract] [Full Text] [PDF]  

Marina Sedova and Lothar A. Blatter

Intracellular Sodium Modulates Mitochondrial Calcium Signaling in Vascular Endothelial Cells
J. Biol. Chem. 2000 275: 35402-35407. Published as JBC Papers in Press 10.1074/jbc.M006058200 [Abstract] [Full Text] [PDF]  

Juan Zhang, Melvin L. Billingsley, Randall L. Kincaid, and Reuben P. Siraganian

Phosphorylation of Syk Activation Loop Tyrosines Is Essential for Syk Function. AN IN VIVO STUDY USING A SPECIFIC ANTI-Syk ACTIVATION LOOP PHOSPHOTYROSINE ANTIBODY
J. Biol. Chem. 2000 275: 35442-35447. Published as JBC Papers in Press 10.1074/jbc.M004549200 [Abstract] [Full Text] [PDF]  

Farida Safadi, Vaka S. Reddy, and Anireddy S. N. Reddy

A Pollen-specific Novel Calmodulin-binding Protein with Tetratricopeptide Repeats
J. Biol. Chem. 2000 275: 35457-35470. Published as JBC Papers in Press 10.1074/jbc.M002720200 [Abstract] [Full Text] [PDF]  

Ilana Kronfeld, Gila Kazimirsky, Patricia S. Lorenzo, Susan H. Garfield, Peter M. Blumberg, and Chaya Brodie

Phosphorylation of Protein Kinase C on Distinct Tyrosine Residues Regulates Specific Cellular Functions
J. Biol. Chem. 2000 275: 35491-35498. Published as JBC Papers in Press 10.1074/jbc.M005991200 [Abstract] [Full Text] [PDF]  

Gil Levkowitz, Shlomo Oved, Leah N. Klapper, Daniel Harari, Sara Lavi, Michael Sela, and Yosef Yarden

c-Cbl Is a Suppressor of the Neu Oncogene
J. Biol. Chem. 2000 275: 35532-35539. Published as JBC Papers in Press 10.1074/jbc.M002661200 [Abstract] [Full Text] [PDF]  

Rachel C. Chambers, Patricia Leoni, Olivier P. Blanc-Brude, David E. Wembridge, and Geoffrey J. Laurent

Thrombin Is a Potent Inducer of Connective Tissue Growth Factor Production via Proteolytic Activation of Protease-activated Receptor-1
J. Biol. Chem. 2000 275: 35584-35591. Published as JBC Papers in Press 10.1074/jbc.M003188200 [Abstract] [Full Text] [PDF]  

Yingjie Zhang, Reiko Sugiura, Yabin Lu, Masako Asami, Takuya Maeda, Toshiki Itoh, Tadaomi Takenawa, Hisato Shuntoh, and Takayoshi Kuno

Phosphatidylinositol 4-Phosphate 5-Kinase Its3 and Calcineurin Ppb1 Coordinately Regulate Cytokinesis in Fission Yeast
J. Biol. Chem. 2000 275: 35600-35606. Published as JBC Papers in Press 10.1074/jbc.M005575200 [Abstract] [Full Text] [PDF]  

Nicole A. Bourbon, Jong Yun, and Mark Kester

Ceramide Directly Activates Protein Kinase C to Regulate a Stress-activated Protein Kinase Signaling Complex
J. Biol. Chem. 2000 275: 35617-35623. Published as JBC Papers in Press 10.1074/jbc.M007346200 [Abstract] [Full Text] [PDF]  

Martin Laser, Christopher D. Willey, Wenjing Jiang, George Cooper, IV, Donald R. Menick, Michael R. Zile, and Dhandapani Kuppuswamy

Integrin Activation and Focal Complex Formation in Cardiac Hypertrophy
J. Biol. Chem. 2000 275: 35624-35630. Published as JBC Papers in Press 10.1074/jbc.M006124200 [Abstract] [Full Text] [PDF]  

Molecular Basis Of Cell and Developmental Biology:

Koji Eto, Wilma Puzon-McLaughlin, Dean Sheppard, Atsuko Sehara-Fujisawa, Xi-Ping Zhang, and Yoshikazu Takada

RGD-independent Binding of Integrin ₉₁ to the ADAM-12 and -15 Disintegrin Domains Mediates Cell-Cell Interaction
J. Biol. Chem. 2000 275: 34922-34930. Published as JBC Papers in Press 10.1074/jbc.M001953200 [Abstract] [Full Text] [PDF]  

Hadar Feinberg, Dawn Torgersen, Kurt Drickamer, and William I. Weis

Mechanism of pH-dependent N-Acetylgalactosamine Binding by a Functional Mimic of the Hepatocyte Asialoglycoprotein Receptor
J. Biol. Chem. 2000 275: 35176-35184. Published as JBC Papers in Press 10.1074/jbc.M005557200 [Abstract] [Full Text] [PDF]  

Rick F. Thorne, John F. Marshall, Darren R. Shafren, Peter G. Gibson, Ian R. Hart, and Gordon F. Burns

The Integrins ₃₁ and ₆₁ Physically and Functionally Associate with CD36 in Human Melanoma Cells. REQUIREMENT FOR THE EXTRACELLULAR DOMAIN OF CD36
J. Biol. Chem. 2000 275: 35264-35275. Published as JBC Papers in Press 10.1074/jbc.M003969200 [Abstract] [Full Text] [PDF]  

Weidong Zhu, Ichiro Shiojima, Yukio Hiroi, Yunzeng Zou, Hiroshi Akazawa, Miho Mizukami, Haruhiro Toko, Yoshio Yazaki, Ryozo Nagai, and Issei Komuro

Functional Analyses of Three Csx/Nkx-2.5 Mutations That Cause Human Congenital Heart Disease
J. Biol. Chem. 2000 275: 35291-35296. Published as JBC Papers in Press 10.1074/jbc.M000525200 [Abstract] [Full Text] [PDF]  

Shaohua Li, Lawrence H. Chow, and J. Geoffrey Pickering

Cell Surface-bound Collagenase-1 and Focal Substrate Degradation Stimulate the Rear Release of Motile Vascular Smooth Muscle Cells
J. Biol. Chem. 2000 275: 35384-35392. Published as JBC Papers in Press 10.1074/jbc.M005139200 [Abstract] [Full Text] [PDF] Supplemental Data  

Youmei Wu, Dana Bressette, Jeff A. Carrell, Thomas Kaufman, Ping Feng, Kara Taylor, Yuxiang Gan, Yun Hee Cho, Andy D. Garcia, Elisa Gollatz, Donna Dimke, David LaFleur, Thi Sau Migone, Bernardetta Nardelli, Ping Wei, Steve M. Ruben, Stephen J. Ullrich, Henrik S. Olsen, Palanisamy Kanakaraj, Paul A. Moore, and Kevin P. Baker

Tumor Necrosis Factor (TNF) Receptor Superfamily Member TACI Is a High Affinity Receptor for TNF Family Members APRIL and BLyS
J. Biol. Chem. 2000 275: 35478-35485. Published as JBC Papers in Press 10.1074/jbc.M005224200 [Abstract] [Full Text] [PDF]  

Hong Chen, Bing Hu, Elizabeth A. Allegretto, and John S. Adams

The Vitamin D Response Element-binding Protein. A NOVEL DOMINANT-NEGATIVE REGULATOR OF VITAMIN D-DIRECTED TRANSACTIVATION
J. Biol. Chem. 2000 275: 35557-35564. Published as JBC Papers in Press 10.1074/jbc.M007117200 [Abstract] [Full Text] [PDF]  

Véronique Neaud, Toru Hisaka, Arnaud Monvoisin, Christiane Bedin, Charles Balabaud, Donald C. Foster, Alexis Desmoulière, Walter Kisiel, and Jean Rosenbaum

Paradoxical Pro-invasive Effect of the Serine Proteinase Inhibitor Tissue Factor Pathway Inhibitor-2 on Human Hepatocellular Carcinoma Cells
J. Biol. Chem. 2000 275: 35565-35569. Published as JBC Papers in Press 10.1074/jbc.M006101200 [Abstract] [Full Text] [PDF]  

Bruno Vincent, Erwan Paitel, Yveline Frobert, Sylvain Lehmann, Jacques Grassi, and Frédéric Checler

Phorbol Ester-regulated Cleavage of Normal Prion Protein in HEK293 Human Cells and Murine Neurons
J. Biol. Chem. 2000 275: 35612-35616. Published as JBC Papers in Press 10.1074/jbc.M004628200 [Abstract] [Full Text] [PDF]  

Additions and Corrections:

Steven Ennion, Sarah Hagan, and Richard J. Evans

The role of positively charged amino acids in ATP recognition by human P2X₁ receptors.
J. Biol. Chem. 2000 275: 35656. [Full Text] [PDF]  

Jianbo Yue and Kathleen M. Mulder

Requirement of Ras/MAPK pathway activation by transforming growth factor for transforming growth factor ₁ production in a Smad-dependent pathway.
J. Biol. Chem. 2000 275: 35656. [Full Text] [PDF]  

Maia Moaddel, Lisa A. Falls, and David H. Farrell

The role of A/' fibrinogen in plasma factor XIII activation.
J. Biol. Chem. 2000 275: 35656. [Full Text] [PDF]  

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