Minireviews:

Robert G. Spiro

Glucose Residues as Key Determinants in the Biosynthesis and Quality Control of Glycoproteins with N-Linked Oligosaccharides
J. Biol. Chem. 2000 275: 35657-35660. Published as JBC Papers in Press 10.1074/jbc.R000022200 [Full Text] [PDF]  

Accelerated Publications:

Yuzuru Imai, Mariko Soda, and Ryosuke Takahashi

Parkin Suppresses Unfolded Protein Stress-induced Cell Death through Its E3 Ubiquitin-protein Ligase Activity
J. Biol. Chem. 2000 275: 35661-35664. Published as JBC Papers in Press 10.1074/jbc.C000447200 [Abstract] [Full Text] [PDF]  

Yu-Sheng Cong and Silvia Bacchetti

Histone Deacetylation Is Involved in the Transcriptional Repression of hTERT in Normal Human Cells
J. Biol. Chem. 2000 275: 35665-35668. Published as JBC Papers in Press 10.1074/jbc.C000637200 [Abstract] [Full Text] [PDF]  

Michele D. Vos, Chad A. Ellis, Aaron Bell, Michael J. Birrer, and Geoffrey J. Clark

Ras Uses the Novel Tumor Suppressor RASSF1 as an Effector to Mediate Apoptosis
J. Biol. Chem. 2000 275: 35669-35672. Published as JBC Papers in Press 10.1074/jbc.C000463200 [Abstract] [Full Text] [PDF]  

Meir Aridor and William E. Balch

Kinase Signaling Initiates Coat Complex II (COPII) Recruitment and Export from the Mammalian Endoplasmic Reticulum
J. Biol. Chem. 2000 275: 35673-35676. Published as JBC Papers in Press 10.1074/jbc.C000449200 [Abstract] [Full Text] [PDF]  

Andrew Chi and Robert G. Kemp

The Primordial High Energy Compound: ATP or Inorganic Pyrophosphate?
J. Biol. Chem. 2000 275: 35677-35679. Published as JBC Papers in Press 10.1074/jbc.C000581200 [Abstract] [Full Text] [PDF]  

Marianne J. Ratcliffe, Keiji Itoh, and Sergei Y. Sokol

A Positive Role for the PP2A Catalytic Subunit in Wnt Signal Transduction
J. Biol. Chem. 2000 275: 35680-35683. Published as JBC Papers in Press 10.1074/jbc.C000639200 [Abstract] [Full Text] [PDF]  

DNA: Replication Repair and Recombination:

Philippe Frit, Ruo-Ya Li, Doriane Arzel, Bernard Salles, and Patrick Calsou

Ku Entry into DNA Inhibits Inward DNA Transactions in Vitro
J. Biol. Chem. 2000 275: 35684-35691. Published as JBC Papers in Press 10.1074/jbc.M004315200 [Abstract] [Full Text] [PDF]  

Michal Stros and Eva Muselíková

A Role of Basic Residues and the Putative Intercalating Phenylalanine of the HMG-1 Box B in DNA Supercoiling and Binding to Four-way DNA Junctions
J. Biol. Chem. 2000 275: 35699-35707. Published as JBC Papers in Press 10.1074/jbc.M007167200 [Abstract] [Full Text] [PDF]  

Shyan-Yuan Kao, Francene J. Lemoine, and Susan J. Marriott

Suppression of DNA Repair by Human T Cell Leukemia Virus Type 1 Tax Is Rescued by a Functional p53 Signaling Pathway
J. Biol. Chem. 2000 275: 35926-35931. Published as JBC Papers in Press 10.1074/jbc.M004397200 [Abstract] [Full Text] [PDF]  

Markus Christmann and Bernd Kaina

Nuclear Translocation of Mismatch Repair Proteins MSH2 and MSH6 as a Response of Cells to Alkylating Agents
J. Biol. Chem. 2000 275: 36256-36262. Published as JBC Papers in Press 10.1074/jbc.M005377200 [Abstract] [Full Text] [PDF]  

Genes: Structure and Regulation:

Linda Gorman, Danielle R. Mercatante, and Ryszard Kole

Restoration of Correct Splicing of Thalassemic -Globin Pre-mRNA by Modified U1 snRNAs
J. Biol. Chem. 2000 275: 35914-35919. Published as JBC Papers in Press 10.1074/jbc.M006259200 [Abstract] [Full Text] [PDF]  

Haiyan Wang, Pierre Maechler, Peter A. Antinozzi, Kerstin A. Hagenfeldt, and Claes B. Wollheim

Hepatocyte Nuclear Factor 4 Regulates the Expression of Pancreatic -Cell Genes Implicated in Glucose Metabolism and Nutrient-induced Insulin Secretion
J. Biol. Chem. 2000 275: 35953-35959. Published as JBC Papers in Press 10.1074/jbc.M006612200 [Abstract] [Full Text] [PDF]  

Fiona B. Turner, Shirley M. Taylor, and Richard G. Moran

Expression Patterns of the Multiple Transcripts from the Folylpolyglutamate Synthetase Gene in Human Leukemias and Normal Differentiated Tissues
J. Biol. Chem. 2000 275: 35960-35968. Published as JBC Papers in Press 10.1074/jbc.M005228200 [Abstract] [Full Text] [PDF]  

Edwin J. Routledge, Roger White, Malcolm G. Parker, and John P. Sumpter

Differential Effects of Xenoestrogens on Coactivator Recruitment by Estrogen Receptor (ER) and ER
J. Biol. Chem. 2000 275: 35986-35993. Published as JBC Papers in Press 10.1074/jbc.M006777200 [Abstract] [Full Text] [PDF]  

Elizabeth A. Jones, Jill Conover, and Aviva J. Symes

Identification of a Novel gp130-responsive Site in the Vasoactive Intestinal Peptide Cytokine Response Element
J. Biol. Chem. 2000 275: 36013-36020. Published as JBC Papers in Press 10.1074/jbc.M007373200 [Abstract] [Full Text] [PDF]  

Yariv Houvras, Miriam Benezra, Hongbing Zhang, James J. Manfredi, Barbara L. Weber, and Jonathan D. Licht

BRCA1 Physically and Functionally Interacts with ATF1
J. Biol. Chem. 2000 275: 36230-36237. Published as JBC Papers in Press 10.1074/jbc.M002539200 [Abstract] [Full Text] [PDF]  

Dieter Schmoll, Kay S. Walker, Dario R. Alessi, Rolf Grempler, Ann Burchell, Shaodong Guo, Reinhard Walther, and Terry G. Unterman

Regulation of Glucose-6-phosphatase Gene Expression by Protein Kinase B and the Forkhead Transcription Factor FKHR. EVIDENCE FOR INSULIN RESPONSE UNIT-DEPENDENT AND -INDEPENDENT EFFECTS OF INSULIN ON PROMOTER ACTIVITY
J. Biol. Chem. 2000 275: 36324-36333. Published as JBC Papers in Press 10.1074/jbc.M003616200 [Abstract] [Full Text] [PDF]  

Monia Giampuzzi, Gerardo Botti, Marco Di Duca, Lorenza Arata, GianMarco Ghiggeri, Rosanna Gusmano, Roberto Ravazzolo, and Armando Di Donato

Lysyl Oxidase Activates the Transcription Activity of Human Collagene III Promoter. POSSIBLE INVOLVEMENT OF Ku ANTIGEN
J. Biol. Chem. 2000 275: 36341-36349. Published as JBC Papers in Press 10.1074/jbc.M003362200 [Abstract] [Full Text] [PDF]  

Mat Yamage, Alain Debrabant, and Dennis M. Dwyer

Molecular Characterization of a Hyperinducible, Surface Membrane-anchored, Class I Nuclease of a Trypanosomatid Parasite
J. Biol. Chem. 2000 275: 36369-36379. Published as JBC Papers in Press 10.1074/jbc.M004036200 [Abstract] [Full Text] [PDF]  

Harald Esterbauer, Hannes Oberkofler, Franz Krempler, A. Donny Strosberg, and Wolfgang Patsch

The Uncoupling Protein-3 Gene Is Transcribed from Tissue-specific Promoters in Humans but Not in Rodents
J. Biol. Chem. 2000 275: 36394-36399. Published as JBC Papers in Press 10.1074/jbc.M005713200 [Abstract] [Full Text] [PDF]  

Chung-Fang Lai, Xu Feng, Riko Nishimura, Steven L. Teitelbaum, Louis V. Avioli, F. Patrick Ross, and Su-Li Cheng

Transforming Growth Factor- Up-regulates the ₅ Integrin Subunit Expression via Sp1 and Smad Signaling
J. Biol. Chem. 2000 275: 36400-36406. Published as JBC Papers in Press 10.1074/jbc.M002131200 [Abstract] [Full Text] [PDF]  

Zheng Pan, Liming Zhou, Christopher J. Hetherington, and Dong-Er Zhang

Hepatocytes Contribute to Soluble CD14 Production, and CD14 Expression Is Differentially Regulated in Hepatocytes and Monocytes
J. Biol. Chem. 2000 275: 36430-36435. Published as JBC Papers in Press 10.1074/jbc.M003192200 [Abstract] [Full Text] [PDF]  

Protein Synthesis Post-Translation Modification and Degradation:

Ling Qiu, Claudio Joazeiro, Nan Fang, Hong-Ying Wang, Chris Elly, Yoav Altman, Deyu Fang, Tony Hunter, and Yun-Cai Liu

Recognition and Ubiquitination of Notch by Itch, a Hect-type E3 Ubiquitin Ligase
J. Biol. Chem. 2000 275: 35734-35737. Published as JBC Papers in Press 10.1074/jbc.M007300200 [Abstract] [Full Text] [PDF]  

Tommer Ravid, Ram Doolman, Rachel Avner, Dror Harats, and Joseph Roitelman

The Ubiquitin-Proteasome Pathway Mediates the Regulated Degradation of Mammalian 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase
J. Biol. Chem. 2000 275: 35840-35847. Published as JBC Papers in Press 10.1074/jbc.M004793200 [Abstract] [Full Text] [PDF]  

Eduardo A. Nillni, Charles Vaslet, Mark Harris, Anthony Hollenberg, Christian Bjørbæk, and Jeffrey S. Flier

Leptin Regulates Prothyrotropin-releasing Hormone Biosynthesis. EVIDENCE FOR DIRECT AND INDIRECT PATHWAYS
J. Biol. Chem. 2000 275: 36124-36133. Published as JBC Papers in Press 10.1074/jbc.M003549200 [Abstract] [Full Text] [PDF]  

Gail S. Begley, Barbara C. Furie, Eva Czerwiec, Kevin L. Taylor, Gregg L. Furie, Ludmila Bronstein, Johan Stenflo, and Bruce Furie

A Conserved Motif within the Vitamin K-dependent Carboxylase Gene Is Widely Distributed across Animal Phyla
J. Biol. Chem. 2000 275: 36245-36249. Published as JBC Papers in Press 10.1074/jbc.M003944200 [Abstract] [Full Text] [PDF]  

Jun Chen, Rebecca L. Shpall, Anke Meyerdierks, Mario Hagemeier, Erik C. Böttger, and Louie Naumovski

Interferon-inducible Myc/STAT-interacting Protein Nmi Associates with IFP 35 into a High Molecular Mass Complex and Inhibits Proteasome-mediated Degradation of IFP 35
J. Biol. Chem. 2000 275: 36278-36284. Published as JBC Papers in Press 10.1074/jbc.M006975200 [Abstract] [Full Text] [PDF]  

Adrian Minty, Xavier Dumont, Mourad Kaghad, and Daniel Caput

Covalent Modification of p73 by SUMO-1. TWO-HYBRID SCREENING WITH p73 IDENTIFIES NOVEL SUMO-1-INTERACTING PROTEINS AND A SUMO-1 INTERACTION MOTIF
J. Biol. Chem. 2000 275: 36316-36323. Published as JBC Papers in Press 10.1074/jbc.M004293200 [Abstract] [Full Text] [PDF]  

Protein Structure and Folding:

Daniel Poso, Richard B. Sessions, Mark Lorch, and Anthony R. Clarke

Progressive Stabilization of Intermediate and Transition States in Protein Folding Reactions by Introducing Surface Hydrophobic Residues
J. Biol. Chem. 2000 275: 35723-35726. Published as JBC Papers in Press 10.1074/jbc.M001747200 [Abstract] [Full Text] [PDF]  

Regis Delage-Mourroux, Paolo G. V. Martini, Inho Choi, Dennis M. Kraichely, Jason Hoeksema, and Benita S. Katzenellenbogen

Analysis of Estrogen Receptor Interaction with a Repressor of Estrogen Receptor Activity (REA) and the Regulation of Estrogen Receptor Transcriptional Activity by REA
J. Biol. Chem. 2000 275: 35848-35856. Published as JBC Papers in Press 10.1074/jbc.M001327200 [Abstract] [Full Text] [PDF]  

Dimitrii E. Kamashev, Anna V. Balandina, and Vadim L. Karpov

Tramtrack Protein-DNA Interactions. A CROSS-LINKING STUDY
J. Biol. Chem. 2000 275: 36056-36061. Published as JBC Papers in Press 10.1074/jbc.M001691200 [Abstract] [Full Text] [PDF]  

Peter Steinberger, Jorun K. Sutton, Christoph Rader, Marikka Elia, and Carlos F. Barbas, III

Generation and Characterization of a Recombinant Human CCR5-specific Antibody. A PHAGE DISPLAY APPROACH FOR RABBIT ANTIBODY HUMANIZATION
J. Biol. Chem. 2000 275: 36073-36078. Published as JBC Papers in Press 10.1074/jbc.M002765200 [Abstract] [Full Text] [PDF]  

Mark V. Berjanskii, Michael I. Riley, Anyong Xie, Valentyna Semenchenko, William R. Folk, and Steven R. Van Doren

NMR Structure of the N-terminal J Domain of Murine Polyomavirus T Antigens. IMPLICATIONS FOR DnaJ-LIKE DOMAINS AND FOR MUTATIONS OF T ANTIGENS
J. Biol. Chem. 2000 275: 36094-36103. Published as JBC Papers in Press 10.1074/jbc.M006572200 [Abstract] [Full Text] [PDF]  

Stuart V. Ruffle, Aziz O. Mustafa, Ashraf Kitmitto, Andreas Holzenburg, and Robert C. Ford

The Location of the Mobile Electron Carrier Ferredoxin in Vascular Plant Photosystem I
J. Biol. Chem. 2000 275: 36250-36255. Published as JBC Papers in Press 10.1074/jbc.M006549200 [Abstract] [Full Text] [PDF]  

Olga Tcherkasskaya, Valentina E. Bychkova, Vladimir N. Uversky, and Angela M. Gronenborn

Multisite Fluorescence in Proteins with Multiple Tryptophan Residues. APOMYOGLOBIN NATURAL VARIANTS AND SITE-DIRECTED MUTANTS
J. Biol. Chem. 2000 275: 36285-36294. Published as JBC Papers in Press 10.1074/jbc.M003008200 [Abstract] [Full Text] [PDF]  

David R. Bell and Alan Poland

Binding of Aryl Hydrocarbon Receptor (AhR) to AhR-interacting Protein. THE ROLE OF hsp90
J. Biol. Chem. 2000 275: 36407-36414. Published as JBC Papers in Press 10.1074/jbc.M004236200 [Abstract] [Full Text] [PDF]  

Michael J. Lumb and Christopher J. Danpure

Functional Synergism between the Most Common Polymorphism in Human Alanine:Glyoxylate Aminotransferase and Four of the Most Common Disease-causing Mutations
J. Biol. Chem. 2000 275: 36415-36422. Published as JBC Papers in Press 10.1074/jbc.M006693200 [Abstract] [Full Text] [PDF]  

T. H. Jackson Huang, Dun-Sheng Yang, Paul E. Fraser, and Avijit Chakrabartty

Alternate Aggregation Pathways of the Alzheimer -Amyloid Peptide. AN IN VITRO MODEL OF PREAMYLOID
J. Biol. Chem. 2000 275: 36436-36440. Published as JBC Papers in Press 10.1074/jbc.M005698200 [Abstract] [Full Text] [PDF]  

Enzyme Catalysis and Regulation:

Benjamin Hemmens, Walter Goessler, Kurt Schmidt, and Bernd Mayer

Role of Bound Zinc in Dimer Stabilization but Not Enzyme Activity of Neuronal Nitric-oxide Synthase
J. Biol. Chem. 2000 275: 35786-35791. Published as JBC Papers in Press 10.1074/jbc.M005976200 [Abstract] [Full Text] [PDF]  

Isabelle Schepens, Eric Ruelland, Myroslawa Miginiac-Maslow, Pierre Le Maréchal, and Paulette Decottignies

The Role of Active Site Arginines of Sorghum NADP-Malate Dehydrogenase in Thioredoxin-dependent Activation and Activity
J. Biol. Chem. 2000 275: 35792-35798. Published as JBC Papers in Press 10.1074/jbc.M006526200 [Abstract] [Full Text] [PDF]  

Gundo Wilkening, Thomas Linke, Gunther Uhlhorn-Dierks, and Konrad Sandhoff

Degradation of Membrane-bound Ganglioside GM1. STIMULATION BY BIS(MONOACYLGLYCERO)PHOSPHATE AND THE ACTIVATOR PROTEINS SAP-B AND GM2-AP
J. Biol. Chem. 2000 275: 35814-35819. Published as JBC Papers in Press 10.1074/jbc.M006568200 [Abstract] [Full Text] [PDF]  

Kirill A. Martemyanov and Anatoly T. Gudkov

Domain III of Elongation Factor G from Thermus thermophilus Is Essential for Induction of GTP Hydrolysis on the Ribosome
J. Biol. Chem. 2000 275: 35820-35824. Published as JBC Papers in Press 10.1074/jbc.M002656200 [Abstract] [Full Text] [PDF]  

Andrew Osborne, Roger N. F. Thorneley, Chris Abell, and Stephen Bornemann

Studies with Substrate and Cofactor Analogues Provide Evidence for a Radical Mechanism in the Chorismate Synthase Reaction
J. Biol. Chem. 2000 275: 35825-35830. Published as JBC Papers in Press 10.1074/jbc.M005796200 [Abstract] [Full Text] [PDF]  

Eva González, M. Rosario Fernández, Carol Larroy, Lluís Solà, Miquel A. Pericàs, Xavier Parés, and Josep A. Biosca

Characterization of a (2R,3R)-2,3-Butanediol Dehydrogenase as the Saccharomyces cerevisiae YAL060W Gene Product. DISRUPTION AND INDUCTION OF THE GENE
J. Biol. Chem. 2000 275: 35876-35885. Published as JBC Papers in Press 10.1074/jbc.M003035200 [Abstract] [Full Text] [PDF]  

Sandrine Boschi-Muller, Said Azza, Sarah Sanglier-Cianferani, François Talfournier, Alain Van Dorsselear, and Guy Branlant

A Sulfenic Acid Enzyme Intermediate Is Involved in the Catalytic Mechanism of Peptide Methionine Sulfoxide Reductase from Escherichia coli
J. Biol. Chem. 2000 275: 35908-35913. Published as JBC Papers in Press 10.1074/jbc.M006137200 [Abstract] [Full Text] [PDF]  

Elena Llano, Alberto M. Pendás, Pedro Aza-Blanc, Thomas B. Kornberg, and Carlos López-Otín

Dm1-MMP, a Matrix Metalloproteinase from Drosophila with a Potential Role in Extracellular Matrix Remodeling during Neural Development
J. Biol. Chem. 2000 275: 35978-35985. Published as JBC Papers in Press 10.1074/jbc.M006045200 [Abstract] [Full Text] [PDF]  

Hong Xiang, Richard A. Tschirret-Guth, and Paul R. Ortiz de Montellano

An A245T Mutation Conveys on Cytochrome P450_eryF the Ability to Oxidize Alternative Substrates
J. Biol. Chem. 2000 275: 35999-36006. Published as JBC Papers in Press 10.1074/jbc.M005811200 [Abstract] [Full Text] [PDF]  

Shiow-Ju Lee, Kathy Beckingham, and James T. Stull

Mutations at Lysine 525 of Inducible Nitric-oxide Synthase Affect Its Ca²⁺-independent Activity
J. Biol. Chem. 2000 275: 36067-36072. Published as JBC Papers in Press 10.1074/jbc.M003935200 [Abstract] [Full Text] [PDF]  

Jason Christiansen, Lance C. Seefeldt, and Dennis R. Dean

Competitive Substrate and Inhibitor Interactions at the Physiologically Relevant Active Site of Nitrogenase
J. Biol. Chem. 2000 275: 36104-36107. Published as JBC Papers in Press 10.1074/jbc.M004889200 [Abstract] [Full Text] [PDF]  

Jari Heikkinen, Maija Risteli, Chunguang Wang, Jaana Latvala, Maarit Rossi, Minna Valtavaara, and Raili Myllylä

Lysyl Hydroxylase 3 Is a Multifunctional Protein Possessing Collagen Glucosyltransferase Activity
J. Biol. Chem. 2000 275: 36158-36163. Published as JBC Papers in Press 10.1074/jbc.M006203200 [Abstract] [Full Text] [PDF]  

Christian P. Strassburg, Susanne Kneip, Juliane Topp, Petra Obermayer-Straub, Ayse Barut, Robert H. Tukey, and Michael P. Manns

Polymorphic Gene Regulation and Interindividual Variation of UDP-glucuronosyltransferase Activity in Human Small Intestine
J. Biol. Chem. 2000 275: 36164-36171. Published as JBC Papers in Press 10.1074/jbc.M002180200 [Abstract] [Full Text] [PDF]  

Troy K. Edwards, Ahamed Saleem, Jeffrey A. Shaman, Tracey Dennis, Claudia Gerigk, Elder Oliveros, Marc R. Gartenberg, and Eric H. Rubin

Role for Nucleolin/Nsr1 in the Cellular Localization of Topoisomerase I
J. Biol. Chem. 2000 275: 36181-36188. Published as JBC Papers in Press 10.1074/jbc.M006628200 [Abstract] [Full Text] [PDF]  

Ian J. MacRae, Eissa Hanna, Joseph D. Ho, Andrew J. Fisher, and Irwin H. Segel

Induction of Positive Cooperativity by Amino Acid Replacements within the C-terminal Domain of Penicillium chrysogenum ATP Sulfurylase
J. Biol. Chem. 2000 275: 36303-36310. Published as JBC Papers in Press 10.1074/jbc.M005992200 [Abstract] [Full Text] [PDF]  

Chester L. Drum, Shui-Zhong Yan, Radmila Sarac, Yasuko Mabuchi, Kathy Beckingham, Andrew Bohm, Zenon Grabarek, and Wei-Jen Tang

An Extended Conformation of Calmodulin Induces Interactions between the Structural Domains of Adenylyl Cyclase from Bacillus anthracis to Promote Catalysis
J. Biol. Chem. 2000 275: 36334-36340. Published as JBC Papers in Press 10.1074/jbc.M004778200 [Abstract] [Full Text] [PDF]  

Metabolism and Bioenergetics:

Yasuyuki Kato-Yamada, Masasuke Yoshida, and Toru Hisabori

Movement of the Helical Domain of the Subunit Is Required for the Activation of Thermophilic F₁-ATPase
J. Biol. Chem. 2000 275: 35746-35750. Published as JBC Papers in Press 10.1074/jbc.M006575200 [Abstract] [Full Text] [PDF]  

Raphaël Roduit, Johane Morin, Frédéric Massé, Laura Segall, Enrique Roche, Christopher B. Newgard, Françoise Assimacopoulos-Jeannet, and Marc Prentki

Glucose Down-regulates the Expression of the Peroxisome Proliferator-activated Receptor- Gene in the Pancreatic -Cell
J. Biol. Chem. 2000 275: 35799-35806. Published as JBC Papers in Press 10.1074/jbc.M006001200 [Abstract] [Full Text] [PDF]  

Tania M. Stevanin, Nikolaos Ioannidis, Catherine E. Mills, Sung Oog Kim, Martin N. Hughes, and Robert K. Poole

Flavohemoglobin Hmp Affords Inducible Protection for Escherichia coli Respiration, Catalyzed by Cytochromes bo' or bd, from Nitric Oxide
J. Biol. Chem. 2000 275: 35868-35875. Published as JBC Papers in Press 10.1074/jbc.M002471200 [Abstract] [Full Text] [PDF]  

Sören Petersen, Albert A. de Graaf, Lothar Eggeling, Michael Möllney, Wolfgang Wiechert, and Hermann Sahm

In Vivo Quantification of Parallel and Bidirectional Fluxes in the Anaplerosis of Corynebacterium glutamicum
J. Biol. Chem. 2000 275: 35932-35941. Published as JBC Papers in Press 10.1074/jbc.M908728199 [Abstract] [Full Text] [PDF]  

Glycobiology and Extracellular Matrices:

Yoshihiro Sakamoto, Tomohiko Taguchi, Koichi Honke, Hiroaki Korekane, Hitoshi Watanabe, Yasuo Tano, Naoshi Dohmae, Koji Takio, Akira Horii, and Naoyuki Taniguchi

Molecular Cloning and Expression of cDNA Encoding Chicken UDP-N-acetyl-D-glucosamine (GlcNAc): GlcNAc1-6(GlcNAc1-2)- Man1-R[GlcNAc to Man]1,4N-acetylglucosaminyltransferase VI
J. Biol. Chem. 2000 275: 36029-36034. Published as JBC Papers in Press 10.1074/jbc.M005860200 [Abstract] [Full Text] [PDF]  

Moisés C. M. Cavalcante, Silvana Allodi, Ana-Paula Valente, Anita H. Straus, Hélio K. Takahashi, Paulo A. S. Mourão, and Mauro S. G. Pavão

Occurrence of Heparin in the Invertebrate Styela plicata (Tunicata) Is Restricted to Cell Layers Facing the Outside Environment. AN ANCIENT ROLE IN DEFENSE?
J. Biol. Chem. 2000 275: 36189-36196. Published as JBC Papers in Press 10.1074/jbc.M005830200 [Abstract] [Full Text] [PDF]  

Nachman Mazurek, Jeff Conklin, James C. Byrd, Avraham Raz, and Robert S. Bresalier

Phosphorylation of the -Galactoside-binding Protein Galectin-3 Modulates Binding to Its Ligands
J. Biol. Chem. 2000 275: 36311-36315. Published as JBC Papers in Press 10.1074/jbc.M003831200 [Abstract] [Full Text] [PDF]  

Lipids and Lipoproteins:

Stewart C. Whitman, Alan Daugherty, and Steven R. Post

Macrophage Colony-stimulating Factor Rapidly Enhances -Migrating Very Low Density Lipoprotein Metabolism in Macrophages through Activation of a G_i/o Protein Signaling Pathway
J. Biol. Chem. 2000 275: 35807-35813. Published as JBC Papers in Press 10.1074/jbc.M001797200 [Abstract] [Full Text] [PDF]  

Membrane Transport Structure Function and Biogenesis:

Thanh T. Tran, Wenxuan Dai, and Hemanta K. Sarkar

Cyclosporin A Inhibits Creatine Uptake by Altering Surface Expression of the Creatine Transporter
J. Biol. Chem. 2000 275: 35708-35714. Published as JBC Papers in Press 10.1074/jbc.M005636200 [Abstract] [Full Text] [PDF]  

Virginie Picard, Gregory Govoni, Nada Jabado, and Philippe Gros

Nramp 2 (DCT1/DMT1) Expressed at the Plasma Membrane Transports Iron and Other Divalent Cations into a Calcein-accessible Cytoplasmic Pool
J. Biol. Chem. 2000 275: 35738-35745. Published as JBC Papers in Press 10.1074/jbc.M005387200 [Abstract] [Full Text] [PDF]  

Yasushi Okazaki, Hiroshi Ohno, Kan Takase, Takenori Ochiai, and Takashi Saito

Cell Surface Expression of Calnexin, a Molecular Chaperone in the Endoplasmic Reticulum
J. Biol. Chem. 2000 275: 35751-35758. Published as JBC Papers in Press 10.1074/jbc.M007476200 [Abstract] [Full Text] [PDF]  

Matthew K. Lancaster, Katharine M. Dibb, Claire C. Quinn, Robert Leach, Jong-Kook Lee, John B. C. Findlay, and Mark R. Boyett

Residues and Mechanisms for Slow Activation and Ba²⁺ Block of the Cardiac Muscarinic K⁺ Channel, Kir3.1/Kir3.4
J. Biol. Chem. 2000 275: 35831-35839. Published as JBC Papers in Press 10.1074/jbc.M006565200 [Abstract] [Full Text] [PDF]  

Wei Feng, Guohua Liu, Paul D. Allen, and Isaac N. Pessah

Transmembrane Redox Sensor of Ryanodine Receptor Complex
J. Biol. Chem. 2000 275: 35902-35907. Published as JBC Papers in Press 10.1074/jbc.C000523200 [Abstract] [Full Text] [PDF]  

Yasser A. Mahmmoud, Henrik Vorum, and Flemming Cornelius

Identification of a Phospholemman-like Protein from Shark Rectal Glands. EVIDENCE FOR INDIRECT REGULATION OF Na,K-ATPase BY PROTEIN KINASE C VIA A NOVEL MEMBER OF THE FXYDY FAMILY
J. Biol. Chem. 2000 275: 35969-35977. Published as JBC Papers in Press 10.1074/jbc.M005168200 [Abstract] [Full Text] [PDF]  

Xinhua Li, Kazuo Shimada, Lori A. Showalter, and Steven A. Weinman

Biophysical Properties of ClC-3 Differentiate It from Swelling-activated Chloride Channels in Chinese Hamster Ovary-K1 Cells
J. Biol. Chem. 2000 275: 35994-35998. Published as JBC Papers in Press 10.1074/jbc.M002712200 [Abstract] [Full Text] [PDF]  

Keiko Kashiwagi, Aiko Kuraishi, Hideyuki Tomitori, Atsuko Igarashi, Kazuhiro Nishimura, Akira Shirahata, and Kazuei Igarashi

Identification of the Putrescine Recognition Site on Polyamine Transport Protein PotE
J. Biol. Chem. 2000 275: 36007-36012. Published as JBC Papers in Press 10.1074/jbc.M006083200 [Abstract] [Full Text] [PDF]  

Jun Chen, John S. Mitcheson, Monica Lin, and Michael C. Sanguinetti

Functional Roles of Charged Residues in the Putative Voltage Sensor of the HCN2 Pacemaker Channel
J. Biol. Chem. 2000 275: 36465-36471. Published as JBC Papers in Press 10.1074/jbc.M007034200 [Abstract] [Full Text] [PDF]  

Mechanisms Of Signal Transduction:

Amy K. Roshak, Elizabeth A. Capper, Christopher Stevenson, Christopher Eichman, and Lisa A. Marshall

Human Calcium-independent Phospholipase A₂ Mediates Lymphocyte Proliferation
J. Biol. Chem. 2000 275: 35692-35698. Published as JBC Papers in Press 10.1074/jbc.M002273200 [Abstract] [Full Text] [PDF]  

Paula G. Bertram, Jae H. Choi, John Carvalho, Wandong Ai, Chenbo Zeng, Ting-Fung Chan, and X. F. Steven Zheng

Tripartite Regulation of Gln3p by TOR, Ure2p, and Phosphatases
J. Biol. Chem. 2000 275: 35727-35733. Published as JBC Papers in Press 10.1074/jbc.M004235200 [Abstract] [Full Text] [PDF]  

Bo Segerman, Niklas Larsson, Per Holmfeldt, and Martin Gullberg

Mutational Analysis of Op18/Stathmin-Tubulin-interacting Surfaces. BINDING COOPERATIVITY CONTROLS TUBULIN GTP HYDROLYSIS IN THE TERNARY COMPLEX
J. Biol. Chem. 2000 275: 35759-35766. Published as JBC Papers in Press 10.1074/jbc.M005875200 [Abstract] [Full Text] [PDF]  

Katharine B. Lee, Judith A. Ptasienski, Moritz Bünemann, and M. Marlene Hosey

Acidic Amino Acids Flanking Phosphorylation Sites in the M₂ Muscarinic Receptor Regulate Receptor Phosphorylation, Internalization, and Interaction with Arrestins
J. Biol. Chem. 2000 275: 35767-35777. Published as JBC Papers in Press 10.1074/jbc.M002225200 [Abstract] [Full Text] [PDF]  

Diane L. Persons, Eugenia M. Yazlovitskaya, and Jill C. Pelling

Effect of Extracellular Signal-regulated Kinase on p53 Accumulation in Response to Cisplatin
J. Biol. Chem. 2000 275: 35778-35785. Published as JBC Papers in Press 10.1074/jbc.M004267200 [Abstract] [Full Text] [PDF]  

Hiroshi Sakamoto, Toshio Kitamura, and Akihiko Yoshimura

Mitogen-activated Protein Kinase Plays an Essential Role in the Erythropoietin-dependent Proliferation of CTLL-2 Cells
J. Biol. Chem. 2000 275: 35857-35862. Published as JBC Papers in Press 10.1074/jbc.M006317200 [Abstract] [Full Text] [PDF]  

Faton H. Agani, Paola Pichiule, Juan Carlos Chavez, and Joseph C. LaManna

The Role of Mitochondria in the Regulation of Hypoxia-inducible Factor 1 Expression during Hypoxia
J. Biol. Chem. 2000 275: 35863-35867. Published as JBC Papers in Press 10.1074/jbc.M005643200 [Abstract] [Full Text] [PDF]  

Joelle Dupont, Michael Karas, and Derek LeRoith

The Potentiation of Estrogen on Insulin-like Growth Factor I Action in MCF-7 Human Breast Cancer Cells Includes Cell Cycle Components
J. Biol. Chem. 2000 275: 35893-35901. Published as JBC Papers in Press 10.1074/jbc.M006741200 [Abstract] [Full Text] [PDF]  

Heidemarie I. Krieger-Brauer, Pankaj Medda, and Horst Kather

Basic Fibroblast Growth Factor Utilizes Both Types of Component Subunits of G_s for Dual Signaling in Human Adipocytes. STIMULATION OF ADENYLYL CYCLASE VIA G_s AND INHIBITION OF NADPH OXIDASE BY G_s
J. Biol. Chem. 2000 275: 35920-35925. Published as JBC Papers in Press 10.1074/jbc.M002490200 [Abstract] [Full Text] [PDF]  

Manu V. Chakravarthy, Tsghe W. Abraha, Robert J. Schwartz, Marta L. Fiorotto, and Frank W. Booth

Insulin-like Growth Factor-I Extends in Vitro Replicative Life Span of Skeletal Muscle Satellite Cells by Enhancing G₁/S Cell Cycle Progression via the Activation of Phosphatidylinositol 3'-Kinase/Akt Signaling Pathway
J. Biol. Chem. 2000 275: 35942-35952. Published as JBC Papers in Press 10.1074/jbc.M005832200 [Abstract] [Full Text] [PDF]  

Susana Morelli, Claudia Buitrago, Guillermo Vazquez, Ana R. De Boland, and Ricardo Boland

Involvement of Tyrosine Kinase Activity in 1,25(OH)₂-vitamin D₃ Signal Transduction in Skeletal Muscle Cells
J. Biol. Chem. 2000 275: 36021-36028. Published as JBC Papers in Press 10.1074/jbc.M002025200 [Abstract] [Full Text] [PDF]  

Mei Kong, Catherine Mounier, Jiong Wu, and Barry I. Posner

Epidermal Growth Factor-induced Phosphatidylinositol 3-Kinase Activation and DNA Synthesis. IDENTIFICATION OF Grb2-ASSOCIATED BINDER 2 AS THE MAJOR MEDIATOR IN RAT HEPATOCYTES
J. Biol. Chem. 2000 275: 36035-36042. Published as JBC Papers in Press 10.1074/jbc.M005621200 [Abstract] [Full Text] [PDF]  

Chiara Cabrele, Michael Langer, Reto Bader, Heike A. Wieland, Henri N. Doods, Oliver Zerbe, and Annette G. Beck-Sickinger

The First Selective Agonist for the Neuropeptide YY₅ Receptor Increases Food Intake in Rats
J. Biol. Chem. 2000 275: 36043-36048. Published as JBC Papers in Press 10.1074/jbc.M000626200 [Abstract] [Full Text] [PDF]  

Edwin C. Thrower, Hamid Mobasheri, Sheila Dargan, Phedra Marius, Edward J. A. Lea, and Alan P. Dawson

Interaction of Luminal Calcium and Cytosolic ATP in the Control of Type 1 Inositol (1,4,5)-Trisphosphate Receptor Channels
J. Biol. Chem. 2000 275: 36049-36055. Published as JBC Papers in Press 10.1074/jbc.M000970200 [Abstract] [Full Text] [PDF]  

Pankaj Kapahi, Takayuki Takahashi, Gioacchino Natoli, Stephen R. Adams, Yi Chen, Roger Y. Tsien, and Michael Karin

Inhibition of NF-B Activation by Arsenite through Reaction with a Critical Cysteine in the Activation Loop of IB Kinase
J. Biol. Chem. 2000 275: 36062-36066. Published as JBC Papers in Press 10.1074/jbc.M007204200 [Abstract] [Full Text] [PDF]  

Zhiyong Gao, John Reavey-Cantwell, Robert A. Young, Patricia Jegier, and Bryan A. Wolf

Synaptotagmin III/VII Isoforms Mediate Ca²⁺-induced Insulin Secretion in Pancreatic Islet -Cells
J. Biol. Chem. 2000 275: 36079-36085. Published as JBC Papers in Press 10.1074/jbc.M004284200 [Abstract] [Full Text] [PDF]  

Hsien-yu Wang, Sergey Doronin, and Craig C. Malbon

Insulin Activation of Mitogen-activated Protein Kinases Erk1,2 Is Amplified via -adrenergic Receptor Expression and Requires the Integrity of the Tyr³⁵⁰ of the Receptor
J. Biol. Chem. 2000 275: 36086-36093. Published as JBC Papers in Press 10.1074/jbc.M004404200 [Abstract] [Full Text] [PDF]  

Toshiyuki Obata, Michael B. Yaffe, German G. Leparc, Elizabeth T. Piro, Hiroshi Maegawa, Atsunori Kashiwagi, Ryuichi Kikkawa, and Lewis C. Cantley

Peptide and Protein Library Screening Defines Optimal Substrate Motifs for AKT/PKB
J. Biol. Chem. 2000 275: 36108-36115. Published as JBC Papers in Press 10.1074/jbc.M005497200 [Abstract] [Full Text] [PDF]  

Quintus G. Medley, Carles Serra-Pagès, Elizabeth Iannotti, Katja Seipel, May Tang, Stephen P. O'Brien, and Michel Streuli

The Trio Guanine Nucleotide Exchange Factor Is a RhoA Target. BINDING OF RhoA TO THE TRIO IMMUNOGLOBULIN-LIKE DOMAIN
J. Biol. Chem. 2000 275: 36116-36123. Published as JBC Papers in Press 10.1074/jbc.M003775200 [Abstract] [Full Text] [PDF]  

Rong-Ming Lyu, Patrizia M. Germano, Joon Ki Choi, Sang V. Le, and Joseph R. Pisegna

Identification of an Essential Amino Acid Motif within the C Terminus of the Pituitary Adenylate Cyclase-activating Polypeptide Type I Receptor That Is Critical for Signal Transduction but Not for Receptor Internalization
J. Biol. Chem. 2000 275: 36134-36142. Published as JBC Papers in Press 10.1074/jbc.M004612200 [Abstract] [Full Text] [PDF]  

Srinivasa M. Srinivasula, Pinaki Datta, Xue-Jun Fan, Teresa Fernandes-Alnemri, Ziwei Huang, and Emad S. Alnemri

Molecular Determinants of the Caspase-promoting Activity of Smac/DIABLO and Its Role in the Death Receptor Pathway
J. Biol. Chem. 2000 275: 36152-36157. Published as JBC Papers in Press 10.1074/jbc.C000533200 [Abstract] [Full Text] [PDF]  

Victoria A. Barton, Mark A. Hall, Keith R. Hudson, and John K. Heath

Interleukin-11 Signals through the Formation of a Hexameric Receptor Complex
J. Biol. Chem. 2000 275: 36197-36203. Published as JBC Papers in Press 10.1074/jbc.M004648200 [Abstract] [Full Text] [PDF]  

Tanya M. Jelacic, Matthew E. Kennedy, Kevin Wickman, and David E. Clapham

Functional and Biochemical Evidence for G-protein-gated Inwardly Rectifying K⁺ (GIRK) Channels Composed of GIRK2 and GIRK3
J. Biol. Chem. 2000 275: 36211-36216. Published as JBC Papers in Press 10.1074/jbc.M007087200 [Abstract] [Full Text] [PDF]  

SookHee Bang, Eui-Jun Jeong, In-Ki Kim, Yong-Keun Jung, and Key-Sun Kim

Fas- and Tumor Necrosis Factor-mediated Apoptosis Uses the Same Binding Surface of FADD to Trigger Signal Transduction. A TYPICAL MODEL FOR CONVERGENT SIGNAL TRANSDUCTION
J. Biol. Chem. 2000 275: 36217-36222. Published as JBC Papers in Press 10.1074/jbc.M006620200 [Abstract] [Full Text] [PDF]  

Sébastien Carréno, Marie-Estelle Gouze, Stéphane Schaak, Laurent J. Emorine, and Isabelle Maridonneau-Parini

Lack of Palmitoylation Redirects p59^Hck from the Plasma Membrane to p61^Hck-positive Lysosomes
J. Biol. Chem. 2000 275: 36223-36229. Published as JBC Papers in Press 10.1074/jbc.M003901200 [Abstract] [Full Text] [PDF]  

Ratna K. Vadlamudi, Liana Adam, Rui-An Wang, Mahitosh Mandal, Diep Nguyen, Aysegul Sahin, Jonathan Chernoff, Mien-Chie Hung, and Rakesh Kumar

Regulatable Expression of p21-activated Kinase-1 Promotes Anchorage-independent Growth and Abnormal Organization of Mitotic Spindles in Human Epithelial Breast Cancer Cells
J. Biol. Chem. 2000 275: 36238-36244. Published as JBC Papers in Press 10.1074/jbc.M002138200 [Abstract] [Full Text] [PDF]  

Gabriela da Silva Xavier, Aniko Varadi, Edward K. Ainscow, and Guy A. Rutter

Regulation of Gene Expression by Glucose in Pancreatic -Cells (MIN6) via Insulin Secretion and Activation of Phosphatidylinositol 3'-Kinase
J. Biol. Chem. 2000 275: 36269-36277. Published as JBC Papers in Press 10.1074/jbc.M006597200 [Abstract] [Full Text] [PDF]  

Yasuko Yamamura, Xianxin Hua, Svetlana Bergelson, and Harvey F. Lodish

Critical Role of Smads and AP-1 Complex in Transforming Growth Factor--dependent Apoptosis
J. Biol. Chem. 2000 275: 36295-36302. Published as JBC Papers in Press 10.1074/jbc.M006023200 [Abstract] [Full Text] [PDF]  

Corinna Bähr, Andreas Rohwer, Luise Stempka, Gabriele Rincke, Friedrich Marks, and Michael Gschwendt

DIK, a Novel Protein Kinase That Interacts with Protein Kinase C. CLONING, CHARACTERIZATION, AND GENE ANALYSIS
J. Biol. Chem. 2000 275: 36350-36357. Published as JBC Papers in Press 10.1074/jbc.M004771200 [Abstract] [Full Text] [PDF]  

Rina Zilkha-Falb, Ari Barzilai, Ruth Djaldeti, Ilan Ziv, Eldad Melamed, and Anat Shirvan

Involvement of T-complex Protein-1 in Dopamine Triggered Apoptosis in Chick Embryo Sympathetic Neurons
J. Biol. Chem. 2000 275: 36380-36387. Published as JBC Papers in Press 10.1074/jbc.M001692200 [Abstract] [Full Text] [PDF]  

Aristóbolo M. Silva and Luiz F. L. Reis

Sodium Salicylate Induces the Expression of the Immunophilin FKBP51 and Biglycan Genes and Inhibits p34^cdc2 mRNA Both in Vitro and in Vivo
J. Biol. Chem. 2000 275: 36388-36393. Published as JBC Papers in Press 10.1074/jbc.M005887200 [Abstract] [Full Text] [PDF]  

Kyra J. Cowan, Debbie A. Law, and David R. Phillips

Identification of Shc as the Primary Protein Binding to the Tyrosine-phosphorylated ₃ Subunit of _IIb3 during Outside-in Integrin Platelet Signaling
J. Biol. Chem. 2000 275: 36423-36429. Published as JBC Papers in Press 10.1074/jbc.M004068200 [Abstract] [Full Text] [PDF]  

Magali Prigent, Isabelle Barlat, Hanno Langen, and Catherine Dargemont

IB and IB/NF-B Complexes Are Retained in the Cytoplasm through Interaction with a Novel Partner, RasGAP SH3-binding Protein 2
J. Biol. Chem. 2000 275: 36441-36449. Published as JBC Papers in Press 10.1074/jbc.M004751200 [Abstract] [Full Text] [PDF]  

Tamela R. King, Yun Fang, Elizabeth S. Mahon, and Deborah H. Anderson

Using a Phage Display Library to Identify Basic Residues in A-Raf Required to Mediate Binding to the Src Homology 2 Domains of the p85 Subunit of Phosphatidylinositol 3'-Kinase
J. Biol. Chem. 2000 275: 36450-36456. Published as JBC Papers in Press 10.1074/jbc.M004720200 [Abstract] [Full Text] [PDF]  

Molecular Basis Of Cell and Developmental Biology:

Takeo Miyahara, Laura Schrum, Richard Rippe, Shigang Xiong, Hal F. Yee, Jr., Kenta Motomura, Frank A. Anania, Timothy M. Willson, and Hidekazu Tsukamoto

Peroxisome Proliferator-activated Receptors and Hepatic Stellate Cell Activation
J. Biol. Chem. 2000 275: 35715-35722. Published as JBC Papers in Press 10.1074/jbc.M006577200 [Abstract] [Full Text] [PDF]  

Jingyuan Xu, Yiider Tseng, and Denis Wirtz

Strain Hardening of Actin Filament Networks. REGULATION BY THE DYNAMIC CROSS-LINKING PROTEIN -ACTININ
J. Biol. Chem. 2000 275: 35886-35892. Published as JBC Papers in Press 10.1074/jbc.M002377200 [Abstract] [Full Text] [PDF]  

Anja Lambrechts, Adam V. Kwiatkowski, Lorene M. Lanier, James E. Bear, Joel Vandekerckhove, Christophe Ampe, and Frank B. Gertler

cAMP-dependent Protein Kinase Phosphorylation of EVL, a Mena/VASP Relative, Regulates Its Interaction with Actin and SH3 Domains
J. Biol. Chem. 2000 275: 36143-36151. Published as JBC Papers in Press 10.1074/jbc.M006274200 [Abstract] [Full Text] [PDF]  

Donna N. Petersen, George T. Tkalcevic, Amy L. Mansolf, Ramon Rivera-Gonzalez, and Thomas A. Brown

Identification of Osteoblast/Osteocyte Factor 45 (OF45), a Bone-specific cDNA Encoding an RGD-containing Protein That Is Highly Expressed in Osteoblasts and Osteocytes
J. Biol. Chem. 2000 275: 36172-36180. Published as JBC Papers in Press 10.1074/jbc.M003622200 [Abstract] [Full Text] [PDF]  

Sönke Tobaben, Thomas C. Südhof, and Bernd Stahl

The G Protein-coupled Receptor CL1 Interacts Directly with Proteins of the Shank Family
J. Biol. Chem. 2000 275: 36204-36210. Published as JBC Papers in Press 10.1074/jbc.M006448200 [Abstract] [Full Text] [PDF]  

Tatyana A. Kupriyanova and Konstantin V. Kandror

Cellugyrin Is a Marker for a Distinct Population of Intracellular Glut4-containing Vesicles
J. Biol. Chem. 2000 275: 36263-36268. Published as JBC Papers in Press 10.1074/jbc.M002797200 [Abstract] [Full Text] [PDF]  

Silvia Goicoechea, Anthony Wayne Orr, Manuel Antonio Pallero, Paul Eggleton, and Joanne E. Murphy-Ullrich

Thrombospondin Mediates Focal Adhesion Disassembly through Interactions with Cell Surface Calreticulin
J. Biol. Chem. 2000 275: 36358-36368. Published as JBC Papers in Press 10.1074/jbc.M005951200 [Abstract] [Full Text] [PDF]  

Emmanuel Vignal, Marion De Toledo, Franck Comunale, Angela Ladopoulou, Cécile Gauthier-Rouvière, Anne Blangy, and Philippe Fort

Characterization of TCL, a New GTPase of the Rho Family related to TC10 and Cdc42
J. Biol. Chem. 2000 275: 36457-36464. Published as JBC Papers in Press 10.1074/jbc.M003487200 [Abstract] [Full Text] [PDF] Supplemental Data  

Carolyn E. Adler, Tohru Miyoshi-Akiyama, Lourdes M. Aleman, Masamitsu Tanaka, Jodi M. Smith, and Bruce J. Mayer

Abl Family Kinases and Cbl Cooperate with the Nck Adaptor to Modulate Xenopus Development
J. Biol. Chem. 2000 275: 36472-36478. Published as JBC Papers in Press 10.1074/jbc.M005424200 [Abstract] [Full Text] [PDF]  

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