JBC -- Table of Contents (Feb 11 2000, 275, (6))

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Myles H. Akabas: Cystic Fibrosis Transmembrane Conductance Regulator. STRUCTURE AND FUNCTION OF AN EPITHELIAL CHLORIDE CHANNEL
J. Biol. Chem. 2000 275: 3729-3732. [Full Text] [PDF]

Accelerated Publications:

Shiying Chen, Bruce A. Johnson, Ying Li, Susan Aster, Brian McKeever, Ralph Mosley, David E. Moller, and Gaochao Zhou: Both Coactivator LXXLL Motif-dependent and -independent Interactions Are Required for Peroxisome Proliferator-activated Receptor $gamma$ (PPAR $gamma$ ) Function
J. Biol. Chem. 2000 275: 3733-3736. [Abstract] [Full Text] [PDF]

Kaoru Inouye, Shin Mizutani, Hiroshi Koide, and Yoshito Kaziro: Formation of the Ras Dimer Is Essential for Raf-1 Activation
J. Biol. Chem. 2000 275: 3737-3740. [Abstract] [Full Text] [PDF]

Karen Hill, Susan Welti, Jinghua Yu, James T. Murray, Shu-Chin Yip, John S. Condeelis, Jeffrey E. Segall, and Jonathan M. Backer: Specific Requirement for the p85-p110 $alpha$ Phosphatidylinositol 3-Kinase during Epidermal Growth Factor-stimulated Actin Nucleation in Breast Cancer Cells
J. Biol. Chem. 2000 275: 3741-3744. [Abstract] [Full Text] [PDF]

Mariantonietta Rubino, Marta Miaczynska, Roger Lippé, and Marino Zerial: Selective Membrane Recruitment of EEA1 Suggests a Role in Directional Transport of Clathrin-coated Vesicles to Early Endosomes
J. Biol. Chem. 2000 275: 3745-3748. [Abstract] [Full Text] [PDF]

DNA: Replication Repair and Recombination:

Philip R. Dash, Martin L. Read, Kerry D. Fisher, Kenneth A. Howard, Margreet Wolfert, David Oupicky, Vladimir Subr, Jiri Strohalm, Karel Ulbrich, and Leonard W. Seymour: Decreased Binding to Proteins and Cells of Polymeric Gene Delivery Vectors Surface Modified with a Multivalent Hydrophilic Polymer and Retargeting through Attachment of Transferrin
J. Biol. Chem. 2000 275: 3793-3802. [Abstract] [Full Text] [PDF]

Scott Gradia, Samir Acharya, and Richard Fishel: The Role of Mismatched Nucleotides in Activating the hMSH2-hMSH6 Molecular Switch
J. Biol. Chem. 2000 275: 3922-3930. [Abstract] [Full Text] [PDF]

Eugeni A. Namsaraev and Paul Berg: Rad51 Uses One Mechanism to Drive DNA Strand Exchange in Both Directions
J. Biol. Chem. 2000 275: 3970-3976. [Abstract] [Full Text] [PDF]

Elena Mossessova, Cindy Levine, Hong Peng, Pearl Nurse, Soon Bahng, and Kenneth J. Marians: Mutational Analysis of Escherichia coli Topoisomerase IV. I. SELECTION OF DOMINANT-NEGATIVE parE ALLELES
J. Biol. Chem. 2000 275: 4099-4103. [Abstract] [Full Text] [PDF]

Pearl Nurse, Soon Bahng, Elena Mossessova, and Kenneth J. Marians: Mutational Analysis of Escherichia coli Topoisomerase IV. II. ATPase NEGATIVE MUTANTS OF ParE INDUCE HYPER-DNA CLEAVAGE
J. Biol. Chem. 2000 275: 4104-4111. [Abstract] [Full Text] [PDF]

Soon Bahng, Elena Mossessova, Pearl Nurse, and Kenneth J. Marians: Mutational Analysis of Escherichia coli Topoisomerase IV. III. IDENTIFICATION OF A REGION OF ParE INVOLVED IN COVALENT CATALYSIS
J. Biol. Chem. 2000 275: 4112-4117. [Abstract] [Full Text] [PDF]

Piotr Romanowski, Jackie Marr, Mark A. Madine, Alison Rowles, J. Julian Blow, Jean Gautier, and Ronald A. Laskey: Interaction of Xenopus Cdc2·Cyclin A1 with the Origin Recognition Complex
J. Biol. Chem. 2000 275: 4239-4243. [Abstract] [Full Text] [PDF]

G. Sebastiaan Winkler, Sofia J. Araújo, Ulrike Fiedler, Wim Vermeulen, Frederic Coin, Jean-Marc Egly, Jan H. J. Hoeijmakers, Richard D. Wood, H. Th. Marc Timmers, and Geert Weeda: TFIIH with Inactive XPD Helicase Functions in Transcription Initiation but Is Defective in DNA Repair
J. Biol. Chem. 2000 275: 4258-4266. [Abstract] [Full Text] [PDF]

Rabindra Roy, Tapan Biswas, J. Ching Lee, and Sankar Mitra: Mutation of a Unique Aspartate Residue Abolishes the Catalytic Activity but Not Substrate Binding of the Mouse N-Methylpurine-DNA Glycosylase (MPG)
J. Biol. Chem. 2000 275: 4278-4282. [Abstract] [Full Text] [PDF]

Yoshiki Murakumo, Tim Roth, Hideshi Ishii, Debora Rasio, Shin-ichiro Numata, Carlo M. Croce, and Richard Fishel: A Human REV7 Homolog That Interacts with the Polymerase $zeta$ Catalytic Subunit hREV3 and the Spindle Assembly Checkpoint Protein hMAD2
J. Biol. Chem. 2000 275: 4391-4397. [Abstract] [Full Text] [PDF]

Rajendra Prasad, Grigory L. Dianov, Vilhelm A. Bohr, and Samuel H. Wilson: FEN1 Stimulation of DNA Polymerase $beta$ Mediates an Excision Step in Mammalian Long Patch Base Excision Repair
J. Biol. Chem. 2000 275: 4460-4466. [Abstract] [Full Text] [PDF]

Masaki Makise, Shinji Mima, Tomofusa Tsuchiya, and Tohru Mizushima: Identification of Amino Acids Involved in the Functional Interaction between DnaA Protein and Acidic Phospholipids
J. Biol. Chem. 2000 275: 4513-4518. [Abstract] [Full Text] [PDF]

Genes: Structure and Regulation:

Tamara K. Nowling, Lance R. Johnson, Matthew S. Wiebe, and Angie Rizzino: Identification of the Transactivation Domain of the Transcription Factor Sox-2 and an Associated Co-activator
J. Biol. Chem. 2000 275: 3810-3818. [Abstract] [Full Text] [PDF]

Yves R. Boisclair, Jianrong Wang, Jiarong Shi, Kelley R. Hurst, and Guck T. Ooi: Role of the Suppressor of Cytokine Signaling-3 in Mediating the Inhibitory Effects of Interleukin-1 $beta$ on the Growth Hormone-dependent Transcription of the Acid-labile Subunit Gene in Liver Cells
J. Biol. Chem. 2000 275: 3841-3847. [Abstract] [Full Text] [PDF]

Whei-meih Chang, Rudi A. Bohm, Jeffrey C. Strauss, Tao Kwan, Tarita Thomas, Roshani B. Cowmeadow, and Nigel S. Atkinson: Muscle-specific Transcriptional Regulation of the slowpoke Ca²⁺-activated K⁺ Channel Gene
J. Biol. Chem. 2000 275: 3991-3998. [Abstract] [Full Text] [PDF]

Vinay Bhaskar, Scott A. Valentine, and Albert J. Courey: A Functional Interaction between Dorsal and Components of the Smt3 Conjugation Machinery
J. Biol. Chem. 2000 275: 4033-4040. [Abstract] [Full Text] [PDF]

Guo-Guang Ying, Paul Proost, Jo van Damme, Maurizio Bruschi, Martino Introna, and Josée Golay: Nucleolin, a Novel Partner for the Myb Transcription Factor Family That Regulates Their Activity
J. Biol. Chem. 2000 275: 4152-4158. [Abstract] [Full Text] [PDF]

Bharatkumar N. Patel, Robert J. Dunn, and Samuel David: Alternative RNA Splicing Generates a Glycosylphosphatidylinositol-anchored Form of Ceruloplasmin in Mammalian Brain
J. Biol. Chem. 2000 275: 4305-4310. [Abstract] [Full Text] [PDF]

Altaf Kassam, Christopher J. Winrow, Françoise Fernandez-Rachubinski, John P. Capone, and Richard A. Rachubinski: The Peroxisome Proliferator Response Element of the Gene Encoding the Peroxisomal $beta$ -Oxidation Enzyme Enoyl-CoA Hydratase/3-Hydroxyacyl-CoA Dehydrogenase Is a Target for Constitutive Androstane Receptor $beta$ /9-cis-Retinoic Acid Receptor-mediated Transactivation
J. Biol. Chem. 2000 275: 4345-4350. [Abstract] [Full Text] [PDF]

Toshifumi Tetsuka, Hiroaki Uranishi, Hiroto Imai, Takao Ono, Shin-ichi Sonta, Naoko Takahashi, Kaori Asamitsu, and Takashi Okamoto: Inhibition of Nuclear Factor- $kappa$ B-mediated Transcription by Association with the Amino-terminal Enhancer of Split, a Groucho-related Protein Lacking WD40 Repeats
J. Biol. Chem. 2000 275: 4383-4390. [Abstract] [Full Text] [PDF]

Qianghua Hu and Sankar N. Maity: Stable Expression of a Dominant Negative Mutant of CCAAT Binding Factor/NF-Y in Mouse Fibroblast Cells Resulting in Retardation of Cell Growth and Inhibition of Transcription of Various Cellular Genes
J. Biol. Chem. 2000 275: 4435-4444. [Abstract] [Full Text] [PDF]

Sipo Vanhanen, Mark West, Johan T. M. Kroon, Nigel Lindner, John Casey, Qi Cheng, Kieran M. Elborough, and Antoni R. Slabas: A Consensus Sequence for Long-chain Fatty-acid Alcohol Oxidases from Candida Identifies a Family of Genes Involved in Lipid $omega$ -Oxidation in Yeast with Homologues in Plants and Bacteria
J. Biol. Chem. 2000 275: 4445-4452. [Abstract] [Full Text] [PDF]

Guozhi Xiao, Di Jiang, Peedikayil Thomas, M. Douglas Benson, Kunliang Guan, Gerard Karsenty, and Renny T. Franceschi: MAPK Pathways Activate and Phosphorylate the Osteoblast-specific Transcription Factor, Cbfa1
J. Biol. Chem. 2000 275: 4453-4459. [Abstract] [Full Text] [PDF]

Darrell D. Mousseau, Denis Banville, Denis L'Abbé, Patrice Bouchard, and Shi-Hsiang Shen: PILR $alpha$ , a Novel Immunoreceptor Tyrosine-based Inhibitory Motif-bearing Protein, Recruits SHP-1 upon Tyrosine Phosphorylation and Is Paired with the Truncated Counterpart PILR $beta$
J. Biol. Chem. 2000 275: 4467-4474. [Abstract] [Full Text] [PDF]

John Lynch, Eun-Ran Suh, Debra G. Silberg, Steven Rulyak, Nadine Blanchard, and Peter G. Traber: The Caudal-related Homeodomain Protein Cdx1 Inhibits Proliferation of Intestinal Epithelial Cells by Down-regulation of D-type Cyclins
J. Biol. Chem. 2000 275: 4499-4506. [Abstract] [Full Text] [PDF]

Mônica Senna Salerno, Viatcheslav A. Mordvinov, and Colin J. Sanderson: Binding of Octamer Factors to a Novel 3'-Positive Regulatory Element in the Mouse Interleukin-5 Gene
J. Biol. Chem. 2000 275: 4525-4531. [Abstract] [Full Text] [PDF]

Aijin Wang, Robin Schneider-Broussard, Addanki P. Kumar, Michael C. MacLeod, and David G. Johnson: Regulation of BRCA1 Expression by the Rb-E2F Pathway
J. Biol. Chem. 2000 275: 4532-4536. [Abstract] [Full Text] [PDF]

RNA: Structure Metabolism and Catalysis:

Takehiro Yasukawa, Tsutomu Suzuki, Takeo Suzuki, Takuya Ueda, Shigeo Ohta, and Kimitsuna Watanabe: Modification Defect at Anticodon Wobble Nucleotide of Mitochondrial tRNAs^Leu(UUR) with Pathogenic Mutations of Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Stroke-like Episodes
J. Biol. Chem. 2000 275: 4251-4257. [Abstract] [Full Text] [PDF]

Burns C. Blaxall, Amy C. Pellett, Steven C. Wu, Aldo Pende, and J. David Port: Purification and Characterization of $beta$ -Adrenergic Receptor mRNA-binding Proteins
J. Biol. Chem. 2000 275: 4290-4297. [Abstract] [Full Text] [PDF]

Protein Synthesis Post-Translation Modification and Degradation:

Thorsten Selmer, Jörg Kahnt, Marcel Goubeaud, Seigo Shima, Wolfgang Grabarse, Ulrich Ermler, and Rudolf K. Thauer: The Biosynthesis of Methylated Amino Acids in the Active Site Region of Methyl-coenzyme M Reductase
J. Biol. Chem. 2000 275: 3755-3760. [Abstract] [Full Text] [PDF]

Wei Liao and Lawrence Chan: Apolipoprotein B, a Paradigm for Proteins Regulated by Intracellular Degradation, Does Not Undergo Intracellular Degradation in CaCo2 Cells
J. Biol. Chem. 2000 275: 3950-3956. [Abstract] [Full Text] [PDF]

Brian G. Rowan, Nancy L. Weigel, and Bert W. O'Malley: Phosphorylation of Steroid Receptor Coactivator-1. IDENTIFICATION OF THE PHOSPHORYLATION SITES AND PHOSPHORYLATION THROUGH THE MITOGEN-ACTIVATED PROTEIN KINASE PATHWAY
J. Biol. Chem. 2000 275: 4475-4483. [Abstract] [Full Text] [PDF]

Genomics Proteomics and Bioinformatics:

Dany Munsch, Rie Watanabe-Fukunaga, Jean-Christophe Bourdon, Shigekasu Nagata, Evelyne May, Elisheva Yonish-Rouach, and Philippe Reisdorf: Human and Mouse Fas (APO-1/CD95) Death Receptor Genes Each Contain a p53-responsive Element That Is Activated by p53 Mutants Unable to Induce Apoptosis
J. Biol. Chem. 2000 275: 3867-3872. [Abstract] [Full Text] [PDF]

Protein Structure and Folding:

K. Krishna Sharma, R. Senthil Kumar, G. Suresh Kumar, and P. Thomas Quinn: Synthesis and Characterization of a Peptide Identified as a Functional Element in $alpha$ A-crystallin
J. Biol. Chem. 2000 275: 3767-3771. [Abstract] [Full Text] [PDF]

Raimondo De Cristofaro, Erica De Candia, Sergio Rutella, and Jeffrey I. Weitz: The Asp²⁷²-Glu²⁸² Region of Platelet Glycoprotein Ib $alpha$ Interacts with the Heparin-binding Site of $alpha$ -Thrombin and Protects the Enzyme from the Heparin-catalyzed Inhibition by Antithrombin III
J. Biol. Chem. 2000 275: 3887-3895. [Abstract] [Full Text] [PDF]

Almerinda Di Venere, Antonello Rossi, Fabio De Matteis, Nicola Rosato, Alessandro Finazzi Agrò, and Giampiero Mei: Opposite Effects of Ca²⁺ and GTP Binding on Tissue Transglutaminase Tertiary Structure
J. Biol. Chem. 2000 275: 3915-3921. [Abstract] [Full Text] [PDF]

Eve-Isabelle Pécheur, Isabelle Martin, Alain Bienvenüe, Jean-Marie Ruysschaert, and Dick Hoekstra: Protein-induced Fusion Can Be Modulated by Target Membrane Lipids through a Structural Switch at the Level of the Fusion Peptide
J. Biol. Chem. 2000 275: 3936-3942. [Abstract] [Full Text] [PDF]

Qitao Yu, Robert I. Lehrer, and James P. Tam: Engineered Salt-insensitive $alpha$ -Defensins with End-to-end Circularized Structures
J. Biol. Chem. 2000 275: 3943-3949. [Abstract] [Full Text] [PDF]

Jian Yang, Zhiliang Cheng, Tianqi Niu, Xiaoshan Liang, Zhizhuang Joe Zhao, and G. Wayne Zhou: Structural Basis for Substrate Specificity of Protein-tyrosine Phosphatase SHP-1
J. Biol. Chem. 2000 275: 4066-4071. [Abstract] [Full Text] [PDF]

Yves Collette, Stefan Arold, Christophe Picard, Katy Janvier, Serge Benichou, Richard Benarous, Daniel Olive, and Christian Dumas: HIV-2 and SIV Nef Proteins Target Different Src Family SH3 Domains than Does HIV-1 Nef because of a Triple Amino Acid Substitution
J. Biol. Chem. 2000 275: 4171-4176. [Abstract] [Full Text] [PDF]

Craig Smith, Dogaris Estavillo, Jonas Emsley, Laurie A. Bankston, Robert C. Liddington, and Miguel A. Cruz: Mapping the Collagen-binding Site in the I Domain of the Glycoprotein Ia/IIa (Integrin $alpha$ ₂ $beta$ ₁)
J. Biol. Chem. 2000 275: 4205-4209. [Abstract] [Full Text] [PDF]

Dmitri I. Svergun, Marc Malfois, Michel H. J. Koch, Siva R. Wigneshweraraj, and Martin Buck: Low Resolution Structure of the $sigma$ 54 Transcription Factor Revealed by X-ray Solution Scattering
J. Biol. Chem. 2000 275: 4210-4214. [Abstract] [Full Text] [PDF]

Robert G. Angelo and Charles S. Rubin: Characterization of Structural Features That Mediate the Tethering of Caenorhabditis elegans Protein Kinase A to a Novel A Kinase Anchor Protein. INSIGHTS INTO THE ANCHORING OF PKAI ISOFORMS
J. Biol. Chem. 2000 275: 4351-4362. [Abstract] [Full Text] [PDF]

Alexander V. Yakhnin, John J. Trimble, Christopher R. Chiaro, and Paul Babitzke: Effects of Mutations in the L-Tryptophan Binding Pocket of the trp RNA-binding Attenuation Protein of Bacillus subtilis
J. Biol. Chem. 2000 275: 4519-4524. [Abstract] [Full Text] [PDF]

Enzyme Catalysis and Regulation:

Jérôme Duranton, Christian Boudier, Didier Belorgey, Philippe Mellet, and Joseph G. Bieth: DNA Strongly Impairs the Inhibition of Cathepsin G by $alpha$ ₁-Antichymotrypsin and $alpha$ ₁-Proteinase Inhibitor
J. Biol. Chem. 2000 275: 3787-3792. [Abstract] [Full Text] [PDF]

Simon Amadeus Hinke, J. Andrew Pospisilik, Hans-Ulrich Demuth, Susanne Mannhart, Kerstin Kühn-Wache, Torsten Hoffmann, Erica Nishimura, Raymond A. Pederson, and Christopher H. S. McIntosh: Dipeptidyl Peptidase IV (DPIV/CD26) Degradation of Glucagon. CHARACTERIZATION OF GLUCAGON DEGRADATION PRODUCTS AND DPIV-RESISTANT ANALOGS
J. Biol. Chem. 2000 275: 3827-3834. [Abstract] [Full Text] [PDF]

Rakesh Sharma, Christopher Rensing, Barry P. Rosen, and Bharati Mitra: The ATP Hydrolytic Activity of Purified ZntA, a Pb(II)/Cd(II)/Zn(II)-translocating ATPase from Escherichia coli
J. Biol. Chem. 2000 275: 3873-3878. [Abstract] [Full Text] [PDF]

Roberto Contestabile, Sebastiana Angelaccio, Robin Maytum, Francesco Bossa, and Robert A. John: The Contribution of a Conformationally Mobile, Active Site Loop to the Reaction Catalyzed by Glutamate Semialdehyde Aminomutase
J. Biol. Chem. 2000 275: 3879-3886. [Abstract] [Full Text] [PDF]

Hieronim Jakubowski: Calcium-dependent Human Serum Homocysteine Thiolactone Hydrolase. A PROTECTIVE MECHANISM AGAINST PROTEIN N-HOMOCYSTEINYLATION
J. Biol. Chem. 2000 275: 3957-3962. [Abstract] [Full Text] [PDF]

David E. Graham, Cindy L. Bock, Celine Schalk-Hihi, Zichun J. Lu, and George D. Markham: Identification of a Highly Diverged Class of S-Adenosylmethionine Synthetases in the Archaea
J. Biol. Chem. 2000 275: 4055-4059. [Abstract] [Full Text] [PDF]

John C. Taylor and George D. Markham: The Bifunctional Active Site of S-Adenosylmethionine Synthetase. ROLES OF THE BASIC RESIDUES
J. Biol. Chem. 2000 275: 4060-4065. [Abstract] [Full Text] [PDF]

Akiko Futamura and Peter G. W. Gettins: Serine 380 (P14) $right-arrow$ Glutamate Mutation Activates Antithrombin as an Inhibitor of Factor Xa
J. Biol. Chem. 2000 275: 4092-4098. [Abstract] [Full Text] [PDF]

Wei-Hsuan Yu and J. Frederick Woessner, Jr.: Heparan Sulfate Proteoglycans as Extracellular Docking Molecules for Matrilysin (Matrix Metalloproteinase 7)
J. Biol. Chem. 2000 275: 4183-4191. [Abstract] [Full Text] [PDF]

Anthony Persechini, Kenji Yano, and Paul M. Stemmer: Ca²⁺ Binding and Energy Coupling in the Calmodulin-Myosin Light Chain Kinase Complex
J. Biol. Chem. 2000 275: 4199-4204. [Abstract] [Full Text] [PDF]

David Pignol, Laurence Ayvazian, Brigitte Kerfelec, Peter Timmins, Isabelle Crenon, Juan Hermoso, Juan Carlos Fontecilla-Camps, and Catherine Chapus: Critical Role of Micelles in Pancreatic Lipase Activation Revealed by Small Angle Neutron Scattering
J. Biol. Chem. 2000 275: 4220-4224. [Abstract] [Full Text] [PDF]

Fei Wang, Lingfeng Chen, Oreste Arcucci, Estelle V. Harvey, Blair Bowers, Yuhui Xu, John A. Hammer, III, and James R. Sellers: Effect of ADP and Ionic Strength on the Kinetic and Motile Properties of Recombinant Mouse Myosin V
J. Biol. Chem. 2000 275: 4329-4335. [Abstract] [Full Text] [PDF]

Metabolism and Bioenergetics:

Carsten Petersen and Lisbeth Birk Møller: Invariance of the Nucleoside Triphosphate Pools of Escherichia coli with Growth Rate
J. Biol. Chem. 2000 275: 3931-3935. [Abstract] [Full Text] [PDF]

Chi-Meng Tzeng and Arthur Kornberg: The Multiple Activities of Polyphosphate Kinase of Escherichia coli and Their Subunit Structure Determined by Radiation Target Analysis
J. Biol. Chem. 2000 275: 3977-3983. [Abstract] [Full Text] [PDF]

Alessandra Baracca, Silvia Barogi, Valerio Carelli, Giorgio Lenaz, and Giancarlo Solaini: Catalytic Activities of Mitochondrial ATP Synthase in Patients with Mitochondrial DNA T8993G Mutation in the ATPase 6 Gene Encoding Subunit a
J. Biol. Chem. 2000 275: 4177-4182. [Abstract] [Full Text] [PDF]

Glycobiology and Extracellular Matrices:

Michel Gilbert, Jean-Robert Brisson, Marie-France Karwaski, Joseph Michniewicz, Anna-Maria Cunningham, Yuyang Wu, N. Martin Young, and Warren W. Wakarchuk: Biosynthesis of Ganglioside Mimics in Campylobacter jejuni OH4384. IDENTIFICATION OF THE GLYCOSYLTRANSFERASE GENES, ENZYMATIC SYNTHESIS OF MODEL COMPOUNDS, AND CHARACTERIZATION OF NANOMOLE AMOUNTS BY 600-MHz ¹H AND ¹³C NMR ANALYSIS
J. Biol. Chem. 2000 275: 3896-3906. [Abstract] [Full Text] [PDF]

Robert T. Cartee, W. Thomas Forsee, John S. Schutzbach, and Janet Yother: Mechanism of Type 3 Capsular Polysaccharide Synthesis in Streptococcus pneumoniae
J. Biol. Chem. 2000 275: 3907-3914. [Abstract] [Full Text] [PDF]

Andreas R. Klatt, D. Patric Nitsche, Birgit Kobbe, Matthias Mörgelin, Mats Paulsson, and Raimund Wagener: Molecular Structure and Tissue Distribution of Matrilin-3, a Filament-forming Extracellular Matrix Protein Expressed during Skeletal Development
J. Biol. Chem. 2000 275: 3999-4006. [Abstract] [Full Text] [PDF]

John F. Cipollo and Robert B. Trimble: The Accumulation of Man₆GlcNAc₂-PP-dolichol in the Saccharomyces cerevisiae $Delta$ alg9 Mutant Reveals a Regulatory Role for the Alg3p $alpha$ 1,3-Man Middle-arm Addition in Downstream Oligosaccharide-lipid and Glycoprotein Glycan Processing
J. Biol. Chem. 2000 275: 4267-4277. [Abstract] [Full Text] [PDF]

Brett E. Close, Kevin Tao, and Karen J. Colley: Polysialyltransferase-1 Autopolysialylation Is Not Requisite for Polysialylation of Neural Cell Adhesion Molecule
J. Biol. Chem. 2000 275: 4484-4491. [Abstract] [Full Text] [PDF]

Lipids and Lipoproteins:

Jonathan C. Cruz, Shigeki Sugii, Chunjiang Yu, and Ta-Yuan Chang: Role of Niemann-Pick Type C1 Protein in Intracellular Trafficking of Low Density Lipoprotein-derived Cholesterol
J. Biol. Chem. 2000 275: 4013-4021. [Abstract] [Full Text] [PDF]

Jerome M. Lasker, W. Bill Chen, Imre Wolf, Barbara P. Bloswick, Patricia D. Wilson, and Pnina K. Powell: Formation of 20-Hydroxyeicosatetraenoic Acid, a Vasoactive and Natriuretic Eicosanoid, in Human Kidney. ROLE OF CYP4F2 AND CYP4A11
J. Biol. Chem. 2000 275: 4118-4126. [Abstract] [Full Text] [PDF]

Membrane Transport Structure Function and Biogenesis:

Christie Cefaratti, Andrea Romani, and Antonio Scarpa: Differential Localization and Operation of Distinct Mg²⁺ Transporters in Apical and Basolateral Sides of Rat Liver Plasma Membrane
J. Biol. Chem. 2000 275: 3772-3780. [Abstract] [Full Text] [PDF]

Jie Fu and Gert Kreibich: Retention of Subunits of the Oligosaccharyltransferase Complex in the Endoplasmic Reticulum
J. Biol. Chem. 2000 275: 3984-3990. [Abstract] [Full Text] [PDF]

Nils Lambrecht, Keith Munson, Olga Vagin, and George Sachs: Comparison of Covalent with Reversible Inhibitor Binding Sites of the Gastric H,K-ATPase by Site-directed Mutagenesis
J. Biol. Chem. 2000 275: 4041-4048. [Abstract] [Full Text] [PDF]

Hélène Varoqui, Heming Zhu, Dongdong Yao, Hong Ming, and Jeffrey D. Erickson: Cloning and Functional Identification of a Neuronal Glutamine Transporter
J. Biol. Chem. 2000 275: 4049-4054. [Abstract] [Full Text] [PDF]

Derek P. Nolan, David G. Jackson, Mary J. Biggs, Elaine D. Brabazon, Annette Pays, François Van Laethem, Françoise Paturiaux-Hanocq, John F. Elliot, H. Paul Voorheis, and Etienne Pays: Characterization of a Novel Alanine-rich Protein Located in Surface Microdomains in Trypanosoma brucei
J. Biol. Chem. 2000 275: 4072-4080. [Abstract] [Full Text] [PDF]

Aaron J. Urquhart, Derek Kennedy, Stephen J. Gould, and Denis I. Crane: Interaction of Pex5p, the Type 1 Peroxisome Targeting Signal Receptor, with the Peroxisomal Membrane Proteins Pex14p and Pex13p
J. Biol. Chem. 2000 275: 4127-4136. [Abstract] [Full Text] [PDF]

Andreas Kukol and Isaiah T. Arkin: Structure of the Influenza C Virus CM2 Protein Transmembrane Domain Obtained by Site-specific Infrared Dichroism and Global Molecular Dynamics Searching
J. Biol. Chem. 2000 275: 4225-4229. [Abstract] [Full Text] [PDF]

Rina Feder, Arie Dagan, and Amram Mor: Structure-Activity Relationship Study of Antimicrobial Dermaseptin S4 Showing the Consequences of Peptide Oligomerization on Selective Cytotoxicity
J. Biol. Chem. 2000 275: 4230-4238. [Abstract] [Full Text] [PDF]

Adelaida G. Filoteo, Ágnes Enyedi, Anil K. Verma, Nancy L. Elwess, and John T. Penniston: Plasma Membrane Ca²⁺ Pump Isoform 3f Is Weakly Stimulated by Calmodulin
J. Biol. Chem. 2000 275: 4323-4328. [Abstract] [Full Text] [PDF]

Pål Ø. Falnes, Sarah Ariansen, Kirsten Sandvig, and Sjur Olsnes: Requirement for Prolonged Action in the Cytosol for Optimal Protein Synthesis Inhibition by Diphtheria Toxin
J. Biol. Chem. 2000 275: 4363-4368. [Abstract] [Full Text] [PDF]

Ande Xu and Njanoor Narayanan: Reversible Inhibition of the Calcium-pumping ATPase in Native Cardiac Sarcoplasmic Reticulum by a Calmodulin-binding Peptide. EVIDENCE FOR CALMODULIN-DEPENDENT REGULATION OF THE V_max OF CALCIUM TRANSPORT
J. Biol. Chem. 2000 275: 4407-4416. [Abstract] [Full Text] [PDF]

Toshiko Kasahara and Michihiro Kasahara: Three Aromatic Amino Acid Residues Critical for Galactose Transport in Yeast Gal2 Transporter
J. Biol. Chem. 2000 275: 4422-4428. [Abstract] [Full Text] [PDF]

Seok Ho Cha, Takashi Sekine, Hiroyuki Kusuhara, Erkang Yu, Ju Young Kim, Do Kyung Kim, Yuichi Sugiyama, Yoshikatsu Kanai, and Hitoshi Endou: Molecular Cloning and Characterization of Multispecific Organic Anion Transporter 4 Expressed in the Placenta
J. Biol. Chem. 2000 275: 4507-4512. [Abstract] [Full Text] [PDF]

Mechanisms Of Signal Transduction:

Sarah K. Hall and David L. Armstrong: Conditional and Unconditional Inhibition of Calcium-activated Potassium Channels by Reversible Protein Phosphorylation
J. Biol. Chem. 2000 275: 3749-3754. [Abstract] [Full Text] [PDF]

Toshifumi Azuma, Kirston Koths, Lisa Flanagan, and David Kwiatkowski: Gelsolin in Complex with Phosphatidylinositol 4,5-Bisphosphate Inhibits Caspase-3 and -9 to Retard Apoptotic Progression
J. Biol. Chem. 2000 275: 3761-3766. [Abstract] [Full Text] [PDF]

Melanie C. MacNicol, Anthony J. Muslin, and Angus M. MacNicol: Disruption of the 14-3-3 Binding Site within the B-Raf Kinase Domain Uncouples Catalytic Activity from PC12 Cell Differentiation
J. Biol. Chem. 2000 275: 3803-3809. [Abstract] [Full Text] [PDF]

Sharon F. Clark, Juan-Carlos Molero, and David E. James: Release of Insulin Receptor Substrate Proteins from an Intracellular Complex Coincides with the Development of Insulin Resistance
J. Biol. Chem. 2000 275: 3819-3826. [Abstract] [Full Text] [PDF]

Helga Schneider, Benoit Guerette, Christine Guntermann, and Christopher E. Rudd: Resting Lymphocyte Kinase (Rlk/Txk) Targets Lymphoid Adaptor SLP-76 in the Cooperative Activation of Interleukin-2 Transcription in T-cells
J. Biol. Chem. 2000 275: 3835-3840. [Abstract] [Full Text] [PDF]

Rudi Vennekens, Joost G. J. Hoenderop, Jean Prenen, Marchel Stuiver, Peter H. G. M. Willems, Guy Droogmans, Bernd Nilius, and René J. M. Bindels: Permeation and Gating Properties of the Novel Epithelial Ca²⁺ Channel
J. Biol. Chem. 2000 275: 3963-3969. [Abstract] [Full Text] [PDF]

Jun Kuai, Annette L. Boman, Rebecca S. Arnold, Xinjun Zhu, and Richard A. Kahn: Effects of Activated ADP-ribosylation Factors on Golgi Morphology Require neither Activation of Phospholipase D1 nor Recruitment of Coatomer
J. Biol. Chem. 2000 275: 4022-4032. [Abstract] [Full Text] [PDF]

Clark Petersen, Nicholas Orem, Joshua Trueheart, Jeremy W. Thorner, and Ian G. Macara: Random Mutagenesis and Functional Analysis of the Ran-binding Protein, RanBP1
J. Biol. Chem. 2000 275: 4081-4091. [Abstract] [Full Text] [PDF]

Kirt W. Braun, Walter A. Tribley, Michael D. Griswold, and Kwan Hee Kim: Follicle-stimulating Hormone Inhibits All-trans-retinoic Acid-induced Retinoic Acid Receptor $alpha$ Nuclear Localization and Transcriptional Activation in Mouse Sertoli Cell Lines
J. Biol. Chem. 2000 275: 4145-4151. [Abstract] [Full Text] [PDF]

Giorgio Zauli, Paola Secchiero, Luigi Rodella, Davide Gibellini, Prisco Mirandola, Meri Mazzoni, Daniela Milani, Diane R. Dowd, Silvano Capitani, and Marco Vitale: HIV-1 Tat-mediated Inhibition of the Tyrosine Hydroxylase Gene Expression in Dopaminergic Neuronal Cells
J. Biol. Chem. 2000 275: 4159-4165. [Abstract] [Full Text] [PDF]

Dmitry Vorobiov, Amal Kanti Bera, Tal Keren-Raifman, Rachel Barzilai, and Nathan Dascal: Coupling of the Muscarinic m2 Receptor to G Protein-activated K⁺ Channels via G $alpha$ _z and a Receptor-G $alpha$ _z Fusion Protein. FUSION BETWEEN THE RECEPTOR AND G $alpha$ _z ELIMINATES CATALYTIC (COLLISION) COUPLING
J. Biol. Chem. 2000 275: 4166-4170. [Abstract] [Full Text] [PDF]

Tara L. McCready, Bonnieca F. Islam, Francis J. Schmitz, Hue A. Luu, John F. Dawson, and Charles F. B. Holmes: Inhibition of Protein Phosphatase-1 by Clavosines A and B. NOVEL MEMBERS OF THE CALYCULIN FAMILY OF TOXINS
J. Biol. Chem. 2000 275: 4192-4198. [Abstract] [Full Text] [PDF]

Liv Thommesen, Kristin Nørsett, Arne K. Sandvik, Eva Hofsli, and Astrid Lægreid: Regulation of Inducible cAMP Early Repressor Expression by Gastrin and Cholecystokinin in the Pancreatic Cell Line AR42J
J. Biol. Chem. 2000 275: 4244-4250. [Abstract] [Full Text] [PDF]

Barry J. Goldstein, Anna Bittner-Kowalczyk, Morris F. White, and Mark Harbeck: Tyrosine Dephosphorylation and Deactivation of Insulin Receptor Substrate-1 by Protein-tyrosine Phosphatase 1B. POSSIBLE FACILITATION BY THE FORMATION OF A TERNARY COMPLEX WITH THE GRB2 ADAPTOR PROTEIN
J. Biol. Chem. 2000 275: 4283-4289. [Abstract] [Full Text] [PDF]

Tanya M. Moore, Ritu Garg, Caroline Johnson, Malcolm J. Coptcoat, Anne J. Ridley, and Jonathan D. H. Morris: PSK, a Novel STE20-like Kinase Derived from Prostatic Carcinoma That Activates the c-Jun N-terminal Kinase Mitogen-activated Protein Kinase Pathway and Regulates Actin Cytoskeletal Organization
J. Biol. Chem. 2000 275: 4311-4322. [Abstract] [Full Text] [PDF]

Peter Brenneisen, Jutta Wenk, Meinhard Wlaschek, Thomas Krieg, and Karin Scharffetter-Kochanek: Activation of p70 Ribosomal Protein S6 Kinase Is an Essential Step in the DNA Damage-dependent Signaling Pathway Responsible for the Ultraviolet B-mediated Increase in Interstitial Collagenase (MMP-1) and Stromelysin-1 (MMP-3) Protein Levels in Human Dermal Fibroblasts
J. Biol. Chem. 2000 275: 4336-4344. [Abstract] [Full Text] [PDF]

Michio Oda, Kazushige Sakitani, Masaki Kaibori, Tomohisa Inoue, Yasuo Kamiyama, and Tadayoshi Okumura: Vicinal Dithiol-binding Agent, Phenylarsine Oxide, Inhibits Inducible Nitric-oxide Synthase Gene Expression at a Step of Nuclear Factor- $kappa$ B DNA Binding in Hepatocytes
J. Biol. Chem. 2000 275: 4369-4373. [Abstract] [Full Text] [PDF]

Aykut Üren, Frieda Reichsman, Vasiliki Anest, William G. Taylor, Kanae Muraiso, Donald P. Bottaro, Susan Cumberledge, and Jeffrey S. Rubin: Secreted Frizzled-related Protein-1 Binds Directly to Wingless and Is a Biphasic Modulator of Wnt Signaling
J. Biol. Chem. 2000 275: 4374-4382. [Abstract] [Full Text] [PDF]

Jacqueline M. Mason, Bryan K. Beattie, Qiurong Liu, Daniel J. Dumont, and Dwayne L. Barber: The SH2 Inositol 5-Phosphatase Ship1 Is Recruited in an SH2-dependent Manner to the Erythropoietin Receptor
J. Biol. Chem. 2000 275: 4398-4406. [Abstract] [Full Text] [PDF]

Robert D. Lasley, Prakash Narayan, Annette Uittenbogaard, and Eric J. Smart: Activated Cardiac Adenosine A₁ Receptors Translocate Out of Caveolae
J. Biol. Chem. 2000 275: 4417-4421. [Abstract] [Full Text] [PDF]

K. M. Faisal Khan and Domenick J. Falcone: Selective Activation of MAPK^erk1/2 by Laminin-1 Peptide $alpha$ 1:Ser²⁰⁹¹-Arg²¹⁰⁸ Regulates Macrophage Degradative Phenotype
J. Biol. Chem. 2000 275: 4492-4498. [Abstract] [Full Text] [PDF]

Molecular Basis Of Cell and Developmental Biology:

Alan M. Fong, Harold P. Erickson, Jason P. Zachariah, Stephen Poon, Neal J. Schamberg, Toshio Imai, and Dhavalkumar D. Patel: Ultrastructure and Function of the Fractalkine Mucin Domain in CX₃C Chemokine Domain Presentation
J. Biol. Chem. 2000 275: 3781-3786. [Abstract] [Full Text] [PDF]

Robert A. Erdman, Kathleen E. Shellenberger, Jean H. Overmeyer, and William A. Maltese: Rab24 Is an Atypical Member of the Rab GTPase Family. DEFICIENT GTPase ACTIVITY, GDP DISSOCIATION INHIBITOR INTERACTION, AND PRENYLATION OF Rab24 EXPRESSED IN CULTURED CELLS
J. Biol. Chem. 2000 275: 3848-3856. [Abstract] [Full Text] [PDF]

Grit Angela Meyer and Klaus Dietrich Radsak: Identification of a Novel Signal Sequence That Targets Transmembrane Proteins to the Nuclear Envelope Inner Membrane
J. Biol. Chem. 2000 275: 3857-3866. [Abstract] [Full Text] [PDF]

Emma Williams, Gareth Williams, Barbara J. Gour, Orest W. Blaschuk, and Patrick Doherty: A Novel Family of Cyclic Peptide Antagonists Suggests That N-cadherin Specificity Is Determined by Amino Acids That Flank the HAV Motif
J. Biol. Chem. 2000 275: 4007-4012. [Abstract] [Full Text] [PDF]

Andrew Jakymiw, Eko Raharjo, Jerome B. Rattner, Theophany Eystathioy, Edward K. L. Chan, and Donald J. Fujita: Identification and Characterization of a Novel Golgi Protein, Golgin-67
J. Biol. Chem. 2000 275: 4137-4144. [Abstract] [Full Text] [PDF]

Gregory A. Taylor, Eric Hudson, James H. Resau, and George F. Vande Woude: Regulation of P311 Expression by Met-Hepatocyte Growth Factor/Scatter Factor and the Ubiquitin/Proteasome System
J. Biol. Chem. 2000 275: 4215-4219. [Abstract] [Full Text] [PDF]

Andrew C. S. Saphire, Tinglu Guan, Eric C. Schirmer, Glen R. Nemerow, and Larry Gerace: Nuclear Import of Adenovirus DNA in Vitro Involves the Nuclear Protein Import Pathway and hsc70
J. Biol. Chem. 2000 275: 4298-4304. [Abstract] [Full Text] [PDF]

Christopher A. Salvatore, Stephen L. Tilley, Anne M. Latour, Daniel S. Fletcher, Beverly H. Koller, and Marlene A. Jacobson: Disruption of the A₃ Adenosine Receptor Gene in Mice and Its Effect on Stimulated Inflammatory Cells
J. Biol. Chem. 2000 275: 4429-4434. [Abstract] [Full Text] [PDF]