Accelerated Publications:

Kazuhiro Ishiguro, Kenji Kadomatsu, Tetsuhito Kojima, Hisako Muramatsu, Shinobu Tsuzuki, Eishin Nakamura, Kazuo Kusugami, Hidehiko Saito, and Takashi Muramatsu

Syndecan-4 Deficiency Impairs Focal Adhesion Formation Only under Restricted Conditions
J. Biol. Chem. 2000 275: 5249-5252. [Abstract] [Full Text] [PDF]  

Tip W. Loo and David M. Clarke

The Packing of the Transmembrane Segments of Human Multidrug Resistance P-glycoprotein Is Revealed by Disulfide Cross-linking Analysis
J. Biol. Chem. 2000 275: 5253-5256. [Abstract] [Full Text] [PDF]  

DNA: Replication Repair and Recombination:

Chang-Xi Zhu and Yuk-Ching Tse-Dinh

The Acidic Triad Conserved in Type IA DNA Topoisomerases Is Required for Binding of Mg(II) and Subsequent Conformational Change
J. Biol. Chem. 2000 275: 5318-5322. [Abstract] [Full Text] [PDF]  

Jun Nakamura, David K. La, and James A. Swenberg

5'-Nicked Apurinic/Apyrimidinic Sites Are Resistant to -Elimination by -Polymerase and Are Persistent in Human Cultured Cells after Oxidative Stress
J. Biol. Chem. 2000 275: 5323-5328. [Abstract] [Full Text] [PDF]  

Chiara Rampazzo, Magnus Johansson, Lisa Gallinaro, Paola Ferraro, Ulf Hellman, Anna Karlsson, Peter Reichard, and Vera Bianchi

Mammalian 5'(3')-Deoxyribonucleotidase, cDNA Cloning, and Overexpression of the Enzyme in Escherichia coli and Mammalian Cells
J. Biol. Chem. 2000 275: 5409-5415. [Abstract] [Full Text] [PDF]  

Laura D. Nelson, Marco Musso, and Michael W. Van Dyke

The Yeast STM1 Gene Encodes a Purine Motif Triple Helical DNA-binding Protein
J. Biol. Chem. 2000 275: 5573-5581. [Abstract] [Full Text] [PDF]  

Alireza Aslani, Stina Simonsson, and Per Elias

A Novel Conformation of the Herpes Simplex Virus Origin of DNA Replication Recognized by the Origin Binding Protein
J. Biol. Chem. 2000 275: 5880-5887. [Abstract] [Full Text] [PDF]  

Yasutoshi Tatsumi, Toshiki Tsurimoto, Katsuhiko Shirahige, Hiroshi Yoshikawa, and Chikashi Obuse

Association of Human Origin Recognition Complex 1 with Chromatin DNA and Nuclease-resistant Nuclear Structures
J. Biol. Chem. 2000 275: 5904-5910. [Abstract] [Full Text] [PDF]  

Hirofumi Tachibana, Hirotaka Haruta, Kyoko Ueda, Takanori Chiwata, and Koji Yamada

Induction of Light Chain Replacement in Human Plasma Cells by Caffeine Is Independent from Both the Upregulation of RAG Protein Expression and Germ Line Transcription
J. Biol. Chem. 2000 275: 5927-5933. [Abstract] [Full Text] [PDF]  

William J. Feaver, Wenya Huang, Opher Gileadi, Lawrence Myers, Claes M. Gustafsson, Roger D. Kornberg, and Errol C. Friedberg

Subunit Interactions in Yeast Transcription/Repair Factor TFIIH. REQUIREMENT FOR Tfb3 SUBUNIT IN NUCLEOTIDE EXCISION REPAIR
J. Biol. Chem. 2000 275: 5941-5946. [Abstract] [Full Text] [PDF]  

Genes: Structure and Regulation:

Françoise Caira, Per Antonson, Markku Pelto-Huikko, Eckardt Treuter, and Jan-Åke Gustafsson

Cloning and Characterization of RAP250, a Novel Nuclear Receptor Coactivator
J. Biol. Chem. 2000 275: 5308-5317. [Abstract] [Full Text] [PDF]  

Mark Gurnell, John M. Wentworth, Maura Agostini, Maria Adams, Trevor N. Collingwood, Claudia Provenzano, Paul O. Browne, Odelia Rajanayagam, Thomas P. Burris, John W. Schwabe, Mitchell A. Lazar, and V. Krishna K. Chatterjee

A Dominant-negative Peroxisome Proliferator-activated Receptor  (PPAR) Mutant Is a Constitutive Repressor and Inhibits PPAR-mediated Adipogenesis
J. Biol. Chem. 2000 275: 5754-5759. [Abstract] [Full Text] [PDF]  

Sean M. Crosson and William J. Roesler

Hormonal Regulation of the Phosphoenolpyruvate Carboxykinase Gene. ROLE OF SPECIFIC CCAAT/ENHANCER-BINDING PROTEIN ISOFORMS
J. Biol. Chem. 2000 275: 5804-5809. [Abstract] [Full Text] [PDF]  

Anu Saloheimo, Nina Aro, Marja Ilmén, and Merja Penttilä

Isolation of the ace1 Gene Encoding a Cys₂-His₂ Transcription Factor Involved in Regulation of Activity of the Cellulase Promoter cbh1 of Trichoderma reesei
J. Biol. Chem. 2000 275: 5817-5825. [Abstract] [Full Text] [PDF]  

Hiroshi Kanamori, Sacha Krieg, Chengjian Mao, Vincent A. Di Pippo, Stanley Wang, Deborah A. Zajchowski, and David J. Shapiro

Proteinase Inhibitor 9, an Inhibitor of Granzyme B-mediated Apoptosis, Is a Primary Estrogen-inducible Gene in Human Liver Cells
J. Biol. Chem. 2000 275: 5867-5873. [Abstract] [Full Text] [PDF]  

Ping Xu, Patricia LaVallee, and John R. Hoidal

Repressed Expression of the Human Xanthine Oxidoreductase Gene. E-BOX AND TATA-LIKE ELEMENTS RESTRICT GROUND STATE TRANSCRIPTIONAL ACTIVITY
J. Biol. Chem. 2000 275: 5918-5926. [Abstract] [Full Text] [PDF]  

Gregory Kapatos, Susan L. Stegenga, and Kei Hirayama

Identification and Characterization of Basal and Cyclic AMP Response Elements in the Promoter of the Rat GTP Cyclohydrolase I Gene
J. Biol. Chem. 2000 275: 5947-5957. [Abstract] [Full Text] [PDF]  

Aruna Subramanian and Donald M. Miller

Structural Analysis of -Enolase. MAPPING THE FUNCTIONAL DOMAINS INVOLVED IN DOWN-REGULATION OF THE c-myc PROTOONCOGENE
J. Biol. Chem. 2000 275: 5958-5965. [Abstract] [Full Text] [PDF]  

Christopher Leo, Hui Li, and J. Don Chen

Differential Mechanisms of Nuclear Receptor Regulation by Receptor-associated Coactivator 3
J. Biol. Chem. 2000 275: 5976-5982. [Abstract] [Full Text] [PDF]  

Yuki Fujiki, Tokuyuki Sato, Masaki Ito, and Akira Watanabe

Isolation and Characterization of cDNA Clones for the E1 and E2 Subunits of the Branched-chain -Ketoacid Dehydrogenase Complex in Arabidopsis
J. Biol. Chem. 2000 275: 6007-6013. [Abstract] [Full Text] [PDF]  

RNA: Structure Metabolism and Catalysis:

Jamie J. Arnold and Craig E. Cameron

Poliovirus RNA-dependent RNA Polymerase (3D^pol). ASSEMBLY OF STABLE, ELONGATION-COMPETENT COMPLEXES BY USING A SYMMETRICAL PRIMER-TEMPLATE SUBSTRATE (sym/sub)
J. Biol. Chem. 2000 275: 5329-5336. [Abstract] [Full Text] [PDF]  

Protein Synthesis Post-Translation Modification and Degradation:

Cheng-Xin Gong, Theodore Lidsky, Jerzy Wegiel, Lorinda Zuck, Inge Grundke-Iqbal, and Khalid Iqbal

Phosphorylation of Microtubule-associated Protein Tau Is Regulated by Protein Phosphatase 2A in Mammalian Brain. IMPLICATIONS FOR NEUROFIBRILLARY DEGENERATION IN ALZHEIMER'S DISEASE
J. Biol. Chem. 2000 275: 5535-5544. [Abstract] [Full Text] [PDF]  

Elizabeth Strickland, Kevin Hakala, Philip J. Thomas, and George N. DeMartino

Recognition of Misfolding Proteins by PA700, the Regulatory Subcomplex of the 26 S Proteasome
J. Biol. Chem. 2000 275: 5565-5572. [Abstract] [Full Text] [PDF]  

Mary Ellen Perry, Susan M. Mendrysa, Leslie J. Saucedo, Paul Tannous, and Marisa Holubar

p76^MDM2 Inhibits the Ability of p90^MDM2 to Destabilize p53
J. Biol. Chem. 2000 275: 5733-5738. [Abstract] [Full Text] [PDF]  

Jun Deng, Ruiqin Pan, and Reen Wu

Distinct Roles for Amino- and Carboxyl-terminal Sequences of SPRR1 Protein in the Formation of Cross-linked Envelopes of Conducting Airway Epithelial Cells
J. Biol. Chem. 2000 275: 5739-5747. [Abstract] [Full Text] [PDF]  

Michael Hippler, Klaus Biehler, Anja Krieger-Liszkay, Jeannette van Dillewjin, and Jean-David Rochaix

Limitation in Electron Transfer in Photosystem I Donor Side Mutants of Chlamydomonas reinhardtii. LETHAL PHOTO-OXIDATIVE DAMAGE IN HIGH LIGHT IS OVERCOME IN A SUPPRESSOR STRAIN DEFICIENT IN THE ASSEMBLY OF THE LIGHT HARVESTING COMPLEX
J. Biol. Chem. 2000 275: 5852-5859. [Abstract] [Full Text] [PDF]  

Genomics Proteomics and Bioinformatics:

Adriana Garay-Arroyo, José M. Colmenero-Flores, Alejandro Garciarrubio, and Alejandra A. Covarrubias

Highly Hydrophilic Proteins in Prokaryotes and Eukaryotes Are Common during Conditions of Water Deficit
J. Biol. Chem. 2000 275: 5668-5674. [Abstract] [Full Text] [PDF]  

Lidya B. Sánchez, Michael Y. Galperin, and Miklós Müller

Acetyl-CoA Synthetase from the Amitochondriate Eukaryote Giardia lamblia Belongs to the Newly Recognized Superfamily of Acyl-CoA Synthetases (Nucleoside Diphosphate-forming)
J. Biol. Chem. 2000 275: 5794-5803. [Abstract] [Full Text] [PDF]  

Protein Structure and Folding:

Nora A. Linderoth, Anthony Popowicz, and Srin Sastry

Identification of the Peptide-binding Site in the Heat Shock Chaperone/Tumor Rejection Antigen gp96 (Grp94)
J. Biol. Chem. 2000 275: 5472-5477. [Abstract] [Full Text] [PDF]  

Hitoshi Osaka, Siobhan Malany, Brian E. Molles, Steven M. Sine, and Palmer Taylor

Pairwise Electrostatic Interactions between -Neurotoxins and , , and  Subunits of the Nicotinic Acetylcholine Receptor
J. Biol. Chem. 2000 275: 5478-5484. [Abstract] [Full Text] [PDF]  

Satoshi Mitsuhashi, Tsunehiro Mizushima, Eiki Yamashita, Masaki Yamamoto, Takashi Kumasaka, Hideaki Moriyama, Tatzuo Ueki, Shigetoh Miyachi, and Tomitake Tsukihara

X-ray Structure of -Carbonic Anhydrase from the Red Alga, Porphyridium purpureum, Reveals a Novel Catalytic Site for CO₂ Hydration
J. Biol. Chem. 2000 275: 5521-5526. [Abstract] [Full Text] [PDF]  

Belur N. Manjula, Ashok Malavalli, Paul K. Smith, Nei-Li Chan, Arthur Arnone, Joel M. Friedman, and A. Seetharama Acharya

Cys-93--Succinimidophenyl Polyethylene Glycol 2000 Hemoglobin A. INTRAMOLECULAR CROSS-BRIDGING OF HEMOGLOBIN OUTSIDE THE CENTRAL CAVITY
J. Biol. Chem. 2000 275: 5527-5534. [Abstract] [Full Text] [PDF]  

Jingshan Ren, Jonathan Diprose, Jonathan Warren, Robert M. Esnouf, Louise E. Bird, Shinji Ikemizu, Martin Slater, John Milton, Jan Balzarini, David I. Stuart, and David K. Stammers

Phenylethylthiazolylthiourea (PETT) Non-nucleoside Inhibitors of HIV-1 and HIV-2 Reverse Transcriptases. STRUCTURAL AND BIOCHEMICAL ANALYSES
J. Biol. Chem. 2000 275: 5633-5639. [Abstract] [Full Text] [PDF]  

Christophe Olivier, Patrick Auguste, Marie Chabbert, Eric Lelièvre, Sylvie Chevalier, and Hugues Gascan

Identification of a gp130 Cytokine Receptor Critical Site Involved in Oncostatin M Response
J. Biol. Chem. 2000 275: 5648-5656. [Abstract] [Full Text] [PDF]  

Bernhard Lieb, Benjamin Altenhein, and Jürgen Markl

The Sequence of a Gastropod Hemocyanin (HtH1 from Haliotis tuberculata)
J. Biol. Chem. 2000 275: 5675-5681. [Abstract] [Full Text] [PDF]  

Steven L. Gonias, Aliya Carmichael, Joseph M. Mettenburg, David W. Roadcap, William P. Irvin, and Donna J. Webb

Identical or Overlapping Sequences in the Primary Structure of Human ₂-Macroglobulin Are Responsible for the Binding of Nerve Growth Factor-, Platelet-derived Growth Factor-BB, and Transforming Growth Factor-
J. Biol. Chem. 2000 275: 5826-5831. [Abstract] [Full Text] [PDF]  

Jean-Louis Banères, Françoise Roquet, Aimée Martin, and Joseph Parello

A Minimized Human Integrin ₅₁ That Retains Ligand Recognition
J. Biol. Chem. 2000 275: 5888-5903. [Abstract] [Full Text] [PDF]  

Aurelia Anne Seon, Thierry Nicolas Pierre, Virginie Redeker, Claire Lacombe, Antoine Delfour, Pierre Nicolas, and Mohamed Amiche

Isolation, Structure, Synthesis, and Activity of a New Member of the Calcitonin Gene-related Peptide Family from Frog Skin and Molecular Cloning of Its Precursor
J. Biol. Chem. 2000 275: 5934-5940. [Abstract] [Full Text] [PDF]  

Enzyme Catalysis and Regulation:

Yi Liu and Paul R. Ortiz de Montellano

Reaction Intermediates and Single Turnover Rate Constants for the Oxidation of Heme by Human Heme Oxygenase-1
J. Biol. Chem. 2000 275: 5297-5307. [Abstract] [Full Text] [PDF]  

Husam M. Abu-Soud and Stanley L. Hazen

Nitric Oxide Modulates the Catalytic Activity of Myeloperoxidase
J. Biol. Chem. 2000 275: 5425-5430. [Abstract] [Full Text] [PDF]  

Patricia C. Y. Liaw, Pierre F. Neuenschwander, Mikhail D. Smirnov, and Charles T. Esmon

Mechanisms by Which Soluble Endothelial Cell Protein C Receptor Modulates Protein C and Activated Protein C Function
J. Biol. Chem. 2000 275: 5447-5452. [Abstract] [Full Text] [PDF]  

Jibo Wang, Susanne Bauman, and Roberta F. Colman

Probing Subunit Interactions in Alpha Class Rat Liver Glutathione S-Transferase with the Photoaffinity Label Glutathionyl S-[4-(Succinimidyl)benzophenone]
J. Biol. Chem. 2000 275: 5493-5503. [Abstract] [Full Text] [PDF]  

Sambanthamurthy Soundar, Brenda L. Danek, and Roberta F. Colman

Identification by Mutagenesis of Arginines in the Substrate Binding Site of the Porcine NADP-dependent Isocitrate Dehydrogenase
J. Biol. Chem. 2000 275: 5606-5612. [Abstract] [Full Text] [PDF]  

Jean Sévigny, Simon C. Robson, Etienne Waelkens, Eva Csizmadia, R. Neal Smith, and Raf Lemmens

Identification and Characterization of a Novel Hepatic Canalicular ATP Diphosphohydrolase
J. Biol. Chem. 2000 275: 5640-5647. [Abstract] [Full Text] [PDF]  

Sung Goo Park, Mee-Kyung Cha, Woojin Jeong, and Il-Han Kim

Distinct Physiological Functions of Thiol Peroxidase Isoenzymes in Saccharomyces cerevisiae
J. Biol. Chem. 2000 275: 5723-5732. [Abstract] [Full Text] [PDF]  

Sharon R. Adderley and Desmond J. Fitzgerald

Glycoprotein IIb/IIIa Antagonists Induce Apoptosis in Rat Cardiomyocytes by Caspase-3 Activation
J. Biol. Chem. 2000 275: 5760-5766. [Abstract] [Full Text] [PDF]  

Noriko Suzuki, Jun Ishizaki, Yasunori Yokota, Ken-ichi Higashino, Takashi Ono, Minoru Ikeda, Noriko Fujii, Keiko Kawamoto, and Kohji Hanasaki

Structures, Enzymatic Properties, and Expression of Novel Human and Mouse Secretory Phospholipase A₂s
J. Biol. Chem. 2000 275: 5785-5793. [Abstract] [Full Text] [PDF]  

Metabolism and Bioenergetics:

Barbara Schoepp, Elodie Chabaud, Cécile Breyton, André Verméglio, and Jean-Luc Popot

On the Spatial Organization of Hemes and Chlorophyll in Cytochrome b₆ f. A LINEAR AND CIRCULAR DICHROISM STUDY
J. Biol. Chem. 2000 275: 5275-5283. [Abstract] [Full Text] [PDF]  

Barbara Schoepp, Jacques Breton, Pierre Parot, and André Verméglio

Relative Orientation of the Hemes of the Cytochrome bc₁ Complexes from Rhodobacter sphaeroides, Rhodospirillum rubrum, and Beef Heart Mitochondria. A LINEAR DICHROISM STUDY
J. Biol. Chem. 2000 275: 5284-5290. [Abstract] [Full Text] [PDF]  

Lianwu Fu, Attila Miseta, Dacia Hunton, Richard B. Marchase, and David M. Bedwell

Loss of the Major Isoform of Phosphoglucomutase Results in Altered Calcium Homeostasis in Saccharomyces cerevisiae
J. Biol. Chem. 2000 275: 5431-5440. [Abstract] [Full Text] [PDF]  

Angela L. McKean, Jinshan Ke, Jianping Song, Ping Che, Sara Achenbach, Basil J. Nikolau, and Eve Syrkin Wurtele

Molecular Characterization of the Non-biotin-containing Subunit of 3-Methylcrotonyl-CoA Carboxylase
J. Biol. Chem. 2000 275: 5582-5590. [Abstract] [Full Text] [PDF]  

Stefan Tomiuk, Markus Zumbansen, and Wilhelm Stoffel

Characterization and Subcellular Localization of Murine and Human Magnesium-dependent Neutral Sphingomyelinase
J. Biol. Chem. 2000 275: 5710-5717. [Abstract] [Full Text] [PDF]  

Zhen-Guo Wang and Sharon H. Ackerman

The Assembly Factor Atp11p Binds to the -Subunit of the Mitochondrial F₁-ATPase
J. Biol. Chem. 2000 275: 5767-5772. [Abstract] [Full Text] [PDF]  

Glycobiology and Extracellular Matrices:

Satoshi Fukumoto, Tatsuro Mutoh, Tomokazu Hasegawa, Hiroshi Miyazaki, Masahiko Okada, George Goto, Keiko Furukawa, Takeshi Urano, and Koichi Furukawa

GD3 Synthase Gene Expression in PC12 Cells Results in the Continuous Activation of TrkA and ERK1/2 and Enhanced Proliferation
J. Biol. Chem. 2000 275: 5832-5838. [Abstract] [Full Text] [PDF]  

Dorin-Bogdan Borza, Kai-Olaf Netzer, Anu Leinonen, Parvin Todd, Javier Cervera, Juan Saus, and Billy G. Hudson

The Goodpasture Autoantigen. IDENTIFICATION OF MULTIPLE CRYPTIC EPITOPES ON THE NC1 DOMAIN OF THE 3(IV) COLLAGEN CHAIN
J. Biol. Chem. 2000 275: 6030-6037. [Abstract] [Full Text] [PDF]  

Lipids and Lipoproteins:

Markku O. Pentikäinen, Katariina Öörni, and Petri T. Kovanen

Lipoprotein Lipase (LPL) Strongly Links Native and Oxidized Low Density Lipoprotein Particles to Decorin-coated Collagen. ROLES FOR BOTH DIMERIC AND MONOMERIC FORMS OF LPL
J. Biol. Chem. 2000 275: 5694-5701. [Abstract] [Full Text] [PDF]  

Membrane Transport Structure Function and Biogenesis:

Hagit Yerushalmi and Shimon Schuldiner

An Essential Glutamyl Residue in EmrE, a Multidrug Antiporter from Escherichia coli
J. Biol. Chem. 2000 275: 5264-5269. [Abstract] [Full Text] [PDF]  

Yoshiyuki Kubo, Satoko Konishi, Tetsuhiro Kawabe, Shigeyuki Nada, and Akihito Yamaguchi

Proximity of Periplasmic Loops in the Metal-Tetracycline/H⁺ Antiporter of Escherichia coli Observed on Site-directed Chemical Cross-linking
J. Biol. Chem. 2000 275: 5270-5274. [Abstract] [Full Text] [PDF]  

William A. Campbell, Deborah E. Sah, Maria M. Medina, Jorge E. Albina, William B. Coleman, and Nancy L. Thompson

TA1/LAT-1/CD98 Light Chain and System L Activity, but Not 4F2/CD98 Heavy Chain, Respond to Arginine Availability in Rat Hepatic Cells. LOSS OF RESPONSE IN TUMOR CELLS
J. Biol. Chem. 2000 275: 5347-5354. [Abstract] [Full Text] [PDF]  

Drake C. Mitchell and Burton J. Litman

Effect of Ethanol and Osmotic Stress on Receptor Conformation. REDUCED WATER ACTIVITY AMPLIFIES THE EFFECT OF ETHANOL ON METARHODOPSIN II FORMATION
J. Biol. Chem. 2000 275: 5355-5360. [Abstract] [Full Text] [PDF]  

Stephan J. Reshkin, Antonia Bellizzi, Valentina Albarani, Lorenzo Guerra, Massimo Tommasino, Angelo Paradiso, and Valeria Casavola

Phosphoinositide 3-Kinase Is Involved in the Tumor-specific Activation of Human Breast Cancer Cell Na⁺/H⁺ Exchange, Motility, and Invasion Induced by Serum Deprivation
J. Biol. Chem. 2000 275: 5361-5369. [Abstract] [Full Text] [PDF]  

Christopher J. R. Loewen and Robert S. Molday

Disulfide-mediated Oligomerization of Peripherin/Rds and Rom-1 in Photoreceptor Disk Membranes. IMPLICATIONS FOR PHOTORECEPTOR OUTER SEGMENT MORPHOGENESIS AND DEGENERATION
J. Biol. Chem. 2000 275: 5370-5378. [Abstract] [Full Text] [PDF]  

Thomas Lykke-Møller Sørensen, Yves Dupont, Bente Vilsen, and Jens Peter Andersen

Fast Kinetic Analysis of Conformational Changes in Mutants of the Ca²⁺-ATPase of Sarcoplasmic Reticulum
J. Biol. Chem. 2000 275: 5400-5408. [Abstract] [Full Text] [PDF]  

Denis Corbeil, Katja Röper, Andrea Hellwig, Manuela Tavian, Sheri Miraglia, Suzanne M. Watt, Paul J. Simmons, Bruno Peault, David W. Buck, and Wieland B. Huttner

The Human AC133 Hematopoietic Stem Cell Antigen Is also Expressed in Epithelial Cells and Targeted to Plasma Membrane Protrusions
J. Biol. Chem. 2000 275: 5512-5520. [Abstract] [Full Text] [PDF]  

L. Alex Gaither and David J. Eide

Functional Expression of the Human hZIP2 Zinc Transporter
J. Biol. Chem. 2000 275: 5560-5564. [Abstract] [Full Text] [PDF]  

Andreas Seyfang and Scott M. Landfear

Four Conserved Cytoplasmic Sequence Motifs Are Important for Transport Function of the Leishmania Inositol/H⁺ Symporter
J. Biol. Chem. 2000 275: 5687-5693. [Abstract] [Full Text] [PDF]  

Ken Sato and Michio Homma

Functional Reconstitution of the Na⁺-driven Polar Flagellar Motor Component of Vibrio alginolyticus
J. Biol. Chem. 2000 275: 5718-5722. [Abstract] [Full Text] [PDF]  

Daniel A. Lawrence, Steven T. Olson, Shabazz Muhammad, Duane E. Day, Jan-Olov Kvassman, David Ginsburg, and Joseph D. Shore

Partitioning of Serpin-Proteinase Reactions between Stable Inhibition and Substrate Cleavage Is Regulated by the Rate of Serpin Reactive Center Loop Insertion into -Sheet A
J. Biol. Chem. 2000 275: 5839-5844. [Abstract] [Full Text] [PDF]  

Wei-Pang Huang, Sidney V. Scott, John Kim, and Daniel J. Klionsky

The Itinerary of a Vesicle Component, Aut7p/Cvt5p, Terminates in the Yeast Vacuole via the Autophagy/Cvt Pathways
J. Biol. Chem. 2000 275: 5845-5851. [Abstract] [Full Text] [PDF]  

Jun Xu, Dongfeng Qu, Naomi L. Esmon, and Charles T. Esmon

Metalloproteolytic Release of Endothelial Cell Protein C Receptor
J. Biol. Chem. 2000 275: 6038-6044. [Abstract] [Full Text] [PDF]  

Mechanisms Of Signal Transduction:

Carlos S. Moreno, Susan Park, Kasey Nelson, Danita Ashby, Frantisek Hubalek, William S. Lane, and David C. Pallas

WD40 Repeat Proteins Striatin and S/G₂ Nuclear Autoantigen Are Members of a Novel Family of Calmodulin-binding Proteins That Associate with Protein Phosphatase 2A
J. Biol. Chem. 2000 275: 5257-5263. [Abstract] [Full Text] [PDF]  

Regina Golser, Antonius C. F. Gorren, Andrea Leber, Penelope Andrew, Hans-Jörg Habisch, Ernst R. Werner, Kurt Schmidt, Richard C. Venema, and Bernd Mayer

Interaction of Endothelial and Neuronal Nitric-oxide Synthases with the Bradykinin B2 Receptor. BINDING OF AN INHIBITORY PEPTIDE TO THE OXYGENASE DOMAIN BLOCKS UNCOUPLED NADPH OXIDATION
J. Biol. Chem. 2000 275: 5291-5296. [Abstract] [Full Text] [PDF]  

Anne E. Anderson, J. Paige Adams, Yan Qian, Richard G. Cook, Paul J. Pfaffinger, and J. David Sweatt

Kv4.2 Phosphorylation by Cyclic AMP-dependent Protein Kinase
J. Biol. Chem. 2000 275: 5337-5346. [Abstract] [Full Text] [PDF]  

Brad Saville, Mark Wormke, Fan Wang, Thu Nguyen, Eva Enmark, George Kuiper, Jan-Åke Gustafsson, and Stephen Safe

Ligand-, Cell-, and Estrogen Receptor Subtype (/)-dependent Activation at GC-rich (Sp1) Promoter Elements
J. Biol. Chem. 2000 275: 5379-5387. [Abstract] [Full Text] [PDF]  

Elda Tagliabue, Fabio Castiglioni, Cristina Ghirelli, Michele Modugno, Laura Asnaghi, Giulia Somenzi, Cecilia Melani, and Sylvie Ménard

Nerve Growth Factor Cooperates with p185^HER2 in Activating Growth of Human Breast Carcinoma Cells
J. Biol. Chem. 2000 275: 5388-5394. [Abstract] [Full Text] [PDF]  

John J. Pink, Sarah M. Planchon, Colleen Tagliarino, Marie E. Varnes, David Siegel, and David A. Boothman

NAD(P)H:Quinone Oxidoreductase Activity Is the Principal Determinant of -Lapachone Cytotoxicity
J. Biol. Chem. 2000 275: 5416-5424. [Abstract] [Full Text] [PDF]  

Mari Kiyono, Yoshito Kaziro, and Takaya Satoh

Induction of Rac-Guanine Nucleotide Exchange Activity of Ras-GRF1/CDC25^Mm following Phosphorylation by the Nonreceptor Tyrosine Kinase Src
J. Biol. Chem. 2000 275: 5441-5446. [Abstract] [Full Text] [PDF]  

Runxiang Zhao and Zhizhuang Joe Zhao

Dissecting the Interaction of SHP-2 with PZR, an Immunoglobulin Family Protein Containing Immunoreceptor Tyrosine-based Inhibitory Motifs
J. Biol. Chem. 2000 275: 5453-5459. [Abstract] [Full Text] [PDF]  

Igor I. Rybkin, Michael E. Cross, E. Michael McReynolds, Richard Z. Lin, and Lisa M. Ballou

_1A Adrenergic Receptor Induces Eukaryotic Initiation Factor 4E-binding Protein 1 Phosphorylation via a Ca²⁺-dependent Pathway Independent of Phosphatidylinositol 3-kinase/Akt
J. Biol. Chem. 2000 275: 5460-5465. [Abstract] [Full Text] [PDF]  

Alison D. Schecter, Tina M. Calderon, Adriane B. Berman, Carrie M. McManus, John T. Fallon, Maria Rossikhina, Weixin Zhao, George Christ, Joan W. Berman, and Mark B. Taubman

Human Vascular Smooth Muscle Cells Possess Functional CCR5
J. Biol. Chem. 2000 275: 5466-5471. [Abstract] [Full Text] [PDF]  

Hiroki Shoji, Kunihiro Tsuchida, Hisashi Kishi, Norio Yamakawa, Takashi Matsuzaki, ZhongHui Liu, Takanori Nakamura, and Hiromu Sugino

Identification and Characterization of a PDZ Protein That Interacts with Activin Type II Receptors
J. Biol. Chem. 2000 275: 5485-5492. [Abstract] [Full Text] [PDF]  

Andrea Huber, Winfried L. Neuhuber, Norbert Klugbauer, Peter Ruth, and Hans-Dieter Allescher

Cysteine-rich Protein 2, a Novel Substrate for cGMP Kinase I in Enteric Neurons and Intestinal Smooth Muscle
J. Biol. Chem. 2000 275: 5504-5511. [Abstract] [Full Text] [PDF]  

R. William Hipkin, Yining Wang, and Agnes Schonbrunn

Protein Kinase C Activation Stimulates the Phosphorylation and Internalization of the sst2A Somatostatin Receptor
J. Biol. Chem. 2000 275: 5591-5599. [Abstract] [Full Text] [PDF]  

Paul R. Graves, Lijia Yu, Julie K. Schwarz, Janis Gales, Edward A. Sausville, Patrick M. O'Connor, and Helen Piwnica-Worms

The Chk1 Protein Kinase and the Cdc25C Regulatory Pathways Are Targets of the Anticancer Agent UCN-01
J. Biol. Chem. 2000 275: 5600-5605. [Abstract] [Full Text] [PDF]  

Chun-Do Oh, Sung-Hee Chang, Young-Mee Yoon, Su-Jae Lee, Yun-Sil Lee, Shin-Sung Kang, and Jang-Soo Chun

Opposing Role of Mitogen-activated Protein Kinase Subtypes, Erk-1/2 and p38, in the Regulation of Chondrogenesis of Mesenchymes
J. Biol. Chem. 2000 275: 5613-5619. [Abstract] [Full Text] [PDF]  

Avron D. Spier and Sarah C. R. Lummis

The Role of Tryptophan Residues in the 5-Hydroxytryptamine₃ Receptor Ligand Binding Domain
J. Biol. Chem. 2000 275: 5620-5625. [Abstract] [Full Text] [PDF]  

Alexei A. Yeliseev and Samuel Kaplan

TspO of Rhodobacter sphaeroides. A STRUCTURAL AND FUNCTIONAL MODEL FOR THE MAMMALIAN PERIPHERAL BENZODIAZEPINE RECEPTOR
J. Biol. Chem. 2000 275: 5657-5667. [Abstract] [Full Text] [PDF]  

Zhi-Liang Lu and Edward C. Hulme

A Network of Conserved Intramolecular Contacts Defines the Off-state of the Transmembrane Switch Mechanism in a Seven-transmembrane Receptor
J. Biol. Chem. 2000 275: 5682-5686. [Abstract] [Full Text] [PDF]  

Michael Beyermann, Sven Rothemund, Nadja Heinrich, Klaus Fechner, Jens Furkert, Margitta Dathe, Rüdiger Winter, Eberhard Krause, and Michael Bienert

A Role for a Helical Connector between Two Receptor Binding Sites of a Long-chain Peptide Hormone
J. Biol. Chem. 2000 275: 5702-5709. [Abstract] [Full Text] [PDF]  

Wolfgang Vogel, Cord Brakebusch, Reinhard Fässler, Frauke Alves, Florence Ruggiero, and Tony Pawson

Discoidin Domain Receptor 1 Is Activated Independently of ₁ Integrin
J. Biol. Chem. 2000 275: 5779-5784. [Abstract] [Full Text] [PDF]  

Takeshi Biwa, Masakazu Sakai, Takeshi Matsumura, Shozo Kobori, Kengo Kaneko, Akira Miyazaki, Hideki Hakamata, Seikoh Horiuchi, and Motoaki Shichiri

Sites of Action of Protein Kinase C and Phosphatidylinositol 3-Kinase Are Distinct in Oxidized Low Density Lipoprotein-induced Macrophage Proliferation
J. Biol. Chem. 2000 275: 5810-5816. [Abstract] [Full Text] [PDF]  

Alexandre Philips, Pierre Roux, Vincent Coulon, Jean-Michel Bellanger, Annick Vié, Marie-Luce Vignais, and Jean Marie Blanchard

Differential Effect of Rac and Cdc42 on p38 Kinase Activity and Cell Cycle Progression of Nonadherent Primary Mouse Fibroblasts
J. Biol. Chem. 2000 275: 5911-5917. [Abstract] [Full Text] [PDF]  

Konstantin V. Salojin, Jian Zhang, Craig Meagher, and Terry L. Delovitch

ZAP-70 Is Essential for the T Cell Antigen Receptor-induced Plasma Membrane Targeting of SOS and Vav in T Cells
J. Biol. Chem. 2000 275: 5966-5975. [Abstract] [Full Text] [PDF]  

Jon A. Ukropec, M. Katherine Hollinger, Steven M. Salva, and Marilyn J. Woolkalis

SHP2 Association with VE-Cadherin Complexes in Human Endothelial Cells Is Regulated by Thrombin
J. Biol. Chem. 2000 275: 5983-5986. [Abstract] [Full Text] [PDF]  

Amber L. Pond, Bridget K. Scheve, Andrew T. Benedict, Kevin Petrecca, David R. Van Wagoner, Alvin Shrier, and Jeanne M. Nerbonne

Expression of Distinct ERG Proteins in Rat, Mouse, and Human Heart. RELATION TO FUNCTIONAL I_Kr CHANNELS
J. Biol. Chem. 2000 275: 5997-6006. [Abstract] [Full Text] [PDF]  

Alice Vallentin, Corinne Prévostel, Teddy Fauquier, Xavier Bonnefont, and Dominique Joubert

Membrane Targeting and Cytoplasmic Sequestration in the Spatiotemporal Localization of Human Protein Kinase C
J. Biol. Chem. 2000 275: 6014-6021. [Abstract] [Full Text] [PDF]  

Jennifer M. Lu-Kuo, David A. Fruman, David M. Joyal, Lewis C. Cantley, and Howard R. Katz

Impaired Kit- but Not FcRI-initiated Mast Cell Activation in the Absence of Phosphoinositide 3-Kinase p85 Gene Products
J. Biol. Chem. 2000 275: 6022-6029. [Abstract] [Full Text] [PDF]  

Molecular Basis Of Cell and Developmental Biology:

Atsushi Takeda, George Perry, Nader G. Abraham, Barney E. Dwyer, R. Krishnan Kutty, Jarmo T. Laitinen, Robert B. Petersen, and Mark A. Smith

Overexpression of Heme Oxygenase in Neuronal Cells, the Possible Interaction with Tau
J. Biol. Chem. 2000 275: 5395-5399. [Abstract] [Full Text] [PDF]  

Michiko Muramatsu, Jun Katada, Izumi Hayashi, and Masataka Majima

Chymase as a Proangiogenic Factor. A POSSIBLE INVOLVEMENT OF CHYMASE-ANGIOTENSIN-DEPENDENT PATHWAY IN THE HAMSTER SPONGE ANGIOGENESIS MODEL
J. Biol. Chem. 2000 275: 5545-5552. [Abstract] [Full Text] [PDF]  

Itaru Matsumura, Hirokazu Tanaka, Akira Kawasaki, Junko Odajima, Hanako Daino, Koji Hashimoto, Hiroshi Wakao, Koichi Nakajima, Takashi Kato, Hiroshi Miyazaki, and Yuzuru Kanakura

Increased D-type Cyclin Expression Together with Decreased cdc2 Activity Confers Megakaryocytic Differentiation of a Human Thrombopoietin-dependent Hematopoietic Cell Line
J. Biol. Chem. 2000 275: 5553-5559. [Abstract] [Full Text] [PDF]  

Hoau-Yan Wang, Daniel H. S. Lee, Michael R. D'Andrea, Per A. Peterson, Richard P. Shank, and Allen B. Reitz

-Amyloid_1-42 Binds to 7 Nicotinic Acetylcholine Receptor with High Affinity. IMPLICATIONS FOR ALZHEIMER'S DISEASE PATHOLOGY
J. Biol. Chem. 2000 275: 5626-5632. [Abstract] [Full Text] [PDF]  

Yuji Shirakata, Toshi Komurasaki, Hitoshi Toyoda, Yasushi Hanakawa, Kenshi Yamasaki, Sho Tokumaru, Koji Sayama, and Koji Hashimoto

Epiregulin, a Novel Member of the Epidermal Growth Factor Family, Is an Autocrine Growth Factor in Normal Human Keratinocytes
J. Biol. Chem. 2000 275: 5748-5753. [Abstract] [Full Text] [PDF]  

Denise Huber, Maria S. Balda, and Karl Matter

Occludin Modulates Transepithelial Migration of Neutrophils
J. Biol. Chem. 2000 275: 5773-5778. [Abstract] [Full Text] [PDF]  

Nirav R. Bhakta, A. Minerva Garcia, Eliot H. Frank, Alan J. Grodzinsky, and Teresa I. Morales

The Insulin-like Growth Factors (IGFs) I and II Bind to Articular Cartilage via the IGF-binding Proteins
J. Biol. Chem. 2000 275: 5860-5866. [Abstract] [Full Text] [PDF]  

Catherine Chaillan-Huntington, Carolina Villa Braslavsky, Jürgen Kuhlmann, and Murray Stewart

Dissecting the Interactions between NTF2, RanGDP, and the Nucleoporin XFXFG Repeats
J. Biol. Chem. 2000 275: 5874-5879. [Abstract] [Full Text] [PDF]  

Simon B. Brown, Murray C. H. Clarke, Lorna Magowan, Heather Sanderson, and John Savill

Constitutive Death of Platelets Leading to Scavenger Receptor-mediated Phagocytosis. A CASPASE-INDEPENDENT CELL CLEARANCE PROGRAM
J. Biol. Chem. 2000 275: 5987-5996. [Abstract] [Full Text] [PDF]  

Additions and Corrections:

Robert J. Kelm, Jr., Paula K. Elder, and Michael J. Getz

The single-stranded DNA-binding proteins, Pur, Pur, and MSY1, specifically interact with an exon 3-derived mouse vascular smooth muscle -actin messenger RNA sequence.
J. Biol. Chem. 2000 275: 6045. [Full Text] [PDF]  

Carlos Henrique I. Ramos

Mapping subdomains in the C-terminal region of troponin I involved in its binding to troponin C and to thin filament.
J. Biol. Chem. 2000 275: 6045. [Full Text] [PDF]  

Satoshi Ota, Kaoru Hazeki, Navin Rao, Mark L. Lupher, Jr., Christopher E. Andoniou, Brian Druker, and Hamid Band

The RING finger domain of Cbl is essential for negative regulation of the Syk tyrosine kinase.
J. Biol. Chem. 2000 275: 6046. [Full Text] [PDF]  

Chunjiang Yu, Jun Chen, Song Lin, Jay Liu, Catherine C. Y. Chang, and Ta-Yuan Chang

Human acyl-CoA: cholesterol acyltransferase-1 is a homotetrameric enzyme in intact cells and in vitro.
J. Biol. Chem. 2000 275: 6046. [Full Text] [PDF]  

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