Minireviews:

Dennis Stuehr, Sovitj Pou, and Gerald M. Rosen

Oxygen Reduction by Nitric-oxide Synthases
J. Biol. Chem. 2001 276: 14533-14536. First Published on March 9, 2001; 10.1074/jbc.R100011200 [Full Text] [PDF]  

Accelerated Publications:

Rintaro Hashizume, Mamoru Fukuda, Ichiro Maeda, Hiroyuki Nishikawa, Daisuke Oyake, Yukari Yabuki, Haruki Ogata, and Tomohiko Ohta

The RING Heterodimer BRCA1-BARD1 Is a Ubiquitin Ligase Inactivated by a Breast Cancer-derived Mutation
J. Biol. Chem. 2001 276: 14537-14540. First Published on March 6, 2001; 10.1074/jbc.C000881200 [Abstract] [Full Text] [PDF]  

Alan K. Howe

Cell Adhesion Regulates the Interaction between Nck and p21-activated Kinase
J. Biol. Chem. 2001 276: 14541-14544. First Published on March 13, 2001; 10.1074/jbc.C000797200 [Abstract] [Full Text] [PDF]  

Dorotea Rigamonti, Simonetta Sipione, Donato Goffredo, Chiara Zuccato, Elisa Fossale, and Elena Cattaneo

Huntingtin's Neuroprotective Activity Occurs via Inhibition of Procaspase-9 Processing
J. Biol. Chem. 2001 276: 14545-14548. First Published on March 5, 2001; 10.1074/jbc.C100044200 [Abstract] [Full Text] [PDF]  

Shilai Bao, Yibing Qyang, Peirong Yang, HyeWon Kim, Hongyan Du, Geoffrey Bartholomeusz, Jenny Henkel, Ruth Pimental, Fulvia Verde, and Stevan Marcus

The Highly Conserved Protein Methyltransferase, Skb1, Is a Mediator of Hyperosmotic Stress Response in the Fission Yeast Schizosaccharomyces pombe
J. Biol. Chem. 2001 276: 14549-14552. First Published on March 9, 2001; 10.1074/jbc.C100096200 [Abstract] [Full Text] [PDF]  

DNA: Replication Repair and Recombination:

Vincent K. Shier, Carey J. Hancey, and Stephen J. Benkovic

Identification of the Active Oligomeric State of an Essential Adenine DNA Methyltransferase from Caulobacter crescentus
J. Biol. Chem. 2001 276: 14744-14751. First Published on February 8, 2001; 10.1074/jbc.M010688200 [Abstract] [Full Text] [PDF]  

Sunil Nayak, Eric L. Hildebrand, and Floyd R. Bryant

ADP-dependent DNA Strand Exchange by the Mutant [P67G/E68A]RecA Protein. EVIDENCE FOR AN INVOLVEMENT OF ADP IN RecA PROTEIN-MEDIATED BRANCH MIGRATION
J. Biol. Chem. 2001 276: 14933-14938. First Published on February 13, 2001; 10.1074/jbc.M100470200 [Abstract] [Full Text] [PDF]  

Yuji Masuda, Mamoru Takahashi, Noriko Tsunekuni, Tomoyuki Minami, Masaharu Sumii, Kiyoshi Miyagawa, and Kenji Kamiya

Deoxycytidyl Transferase Activity of the Human REV1 Protein Is Closely Associated with the Conserved Polymerase Domain
J. Biol. Chem. 2001 276: 15051-15058. First Published on January 22, 2001; 10.1074/jbc.M008082200 [Abstract] [Full Text] [PDF]  

John R. Vance and Thomas E. Wilson

Uncoupling of 3'-Phosphatase and 5'-Kinase Functions in Budding Yeast. CHARACTERIZATION OF SACCHAROMYCES CEREVISIAE DNA 3'-PHOSPHATASE (TPP1)
J. Biol. Chem. 2001 276: 15073-15081. First Published on January 30, 2001; 10.1074/jbc.M011075200 [Abstract] [Full Text] [PDF]  

Tomoko Ishikawa, Norio Uematsu, Toshimi Mizukoshi, Shigenori Iwai, Hiroshi Iwasaki, Chikahide Masutani, Fumio Hanaoka, Ryu Ueda, Haruo Ohmori, and Takeshi Todo

Mutagenic and Nonmutagenic Bypass of DNA Lesions by Drosophila DNA Polymerases dpol and dpol
J. Biol. Chem. 2001 276: 15155-15163. First Published on January 31, 2001; 10.1074/jbc.M009822200 [Abstract] [Full Text] [PDF]  

Thomas W. Burke, Jeanette Gowen Cook, Maki Asano, and Joseph R. Nevins

Replication Factors MCM2 and ORC1 Interact with the Histone Acetyltransferase HBO1
J. Biol. Chem. 2001 276: 15397-15408. First Published on January 24, 2001; 10.1074/jbc.M011556200 [Abstract] [Full Text] [PDF]  

Robin L. Woodard, Kyung-jong Lee, Juren Huang, and William S. Dynan

Distinct Roles for Ku Protein in Transcriptional Reinitiation and DNA Repair
J. Biol. Chem. 2001 276: 15423-15433. First Published on February 2, 2001; 10.1074/jbc.M010752200 [Abstract] [Full Text] [PDF]  

Mitsuo Wakasugi, Mayuko Shimizu, Hiroshi Morioka, Stuart Linn, Osamu Nikaido, and Tsukasa Matsunaga

Damaged DNA-binding Protein DDB Stimulates the Excision of Cyclobutane Pyrimidine Dimers in Vitro in Concert with XPA and Replication Protein A
J. Biol. Chem. 2001 276: 15434-15440. First Published on February 2, 2001; 10.1074/jbc.M011177200 [Abstract] [Full Text] [PDF]  

Genes: Structure and Regulation:

Jocelyn Roy, Marie Audette, and Michel J. Tremblay

Intercellular Adhesion Molecule-1 (ICAM-1) Gene Expression in Human T Cells Is Regulated by Phosphotyrosyl Phosphatase Activity. INVOLVEMENT OF NF-B, Ets, AND PALINDROMIC INTERFERON--RESPONSIVE ELEMENT-BINDING SITES
J. Biol. Chem. 2001 276: 14553-14561. First Published on January 29, 2001; 10.1074/jbc.M005067200 [Abstract] [Full Text] [PDF]  

Anke Geick, Michel Eichelbaum, and Oliver Burk

Nuclear Receptor Response Elements Mediate Induction of Intestinal MDR1 by Rifampin
J. Biol. Chem. 2001 276: 14581-14587. First Published on January 31, 2001; 10.1074/jbc.M010173200 [Abstract] [Full Text] [PDF]  

Laure J. M. Jason, Susan C. Moore, Juan Ausió, and George Lindsey

Magnesium-dependent Association and Folding of Oligonucleosomes Reconstituted with Ubiquitinated H2A
J. Biol. Chem. 2001 276: 14597-14601. First Published on February 2, 2001; 10.1074/jbc.M011153200 [Abstract] [Full Text] [PDF]  

Jiong Wu, Kay M. Parkhurst, Robyn M. Powell, Michael Brenowitz, and Lawrence J. Parkhurst

DNA Bends in TATA-binding Protein·TATA Complexes in Solution Are DNA Sequence-dependent
J. Biol. Chem. 2001 276: 14614-14622. First Published on January 26, 2001; 10.1074/jbc.M004402200 [Abstract] [Full Text] [PDF]  

Jiong Wu, Kay M. Parkhurst, Robyn M. Powell, and Lawrence J. Parkhurst

DNA Sequence-dependent Differences in TATA-binding Protein-induced DNA Bending in Solution Are Highly Sensitive to Osmolytes
J. Biol. Chem. 2001 276: 14623-14627. First Published on January 26, 2001; 10.1074/jbc.M004401200 [Abstract] [Full Text] [PDF]  

Wojciech Frejtag, Yan Zhang, Rujuan Dai, Mark G. Anderson, and Nahid F. Mivechi

Heat Shock Factor-4 (HSF-4a) Represses Basal Transcription through Interaction with TFIIF
J. Biol. Chem. 2001 276: 14685-14694. First Published on February 2, 2001; 10.1074/jbc.M009224200 [Abstract] [Full Text] [PDF]  

Dan J. Mazur and Fred W. Perrino

Structure and Expression of the TREX1 and TREX2 3'5' Exonuclease Genes
J. Biol. Chem. 2001 276: 14718-14727. First Published on January 29, 2001; 10.1074/jbc.M010051200 [Abstract] [Full Text] [PDF]  

Tianru Jin and Huiqin Li

POU Homeodomain Protein OCT1 Is Implicated in the Expression of the Caudal-related Homeobox Gene Cdx-2
J. Biol. Chem. 2001 276: 14752-14758. First Published on February 6, 2001; 10.1074/jbc.M008277200 [Abstract] [Full Text] [PDF]  

Gaku Mizuguchi, Alex Vassilev, Toshio Tsukiyama, Yoshihiro Nakatani, and Carl Wu

ATP-dependent Nucleosome Remodeling and Histone Hyperacetylation Synergistically Facilitate Transcription of Chromatin
J. Biol. Chem. 2001 276: 14773-14783. First Published on February 5, 2001; 10.1074/jbc.M100125200 [Abstract] [Full Text] [PDF]  

Mireia Garriga-Canut, Avtar Roopra, and Noel. J. Buckley

The Basic Helix-Loop-Helix Protein, SHARP-1, Represses Transcription by a Histone Deacetylase-dependent and Histone Deacetylase-independent Mechanism
J. Biol. Chem. 2001 276: 14821-14828. First Published on February 5, 2001; 10.1074/jbc.M011619200 [Abstract] [Full Text] [PDF]  

Concepción Nieto, Antonio Puyet, and Manuel Espinosa

MalR-mediated Regulation of the Streptococcus pneumoniae malMP Operon at Promoter P_M. INFLUENCE OF A PROXIMAL DIVERGENT PROMOTER REGION AND COMPETITION BETWEEN MalR AND RNA POLYMERASE PROTEINS
J. Biol. Chem. 2001 276: 14946-14954. First Published on February 13, 2001; 10.1074/jbc.M010911200 [Abstract] [Full Text] [PDF]  

Yan Sun, Marco D. Wong, and Barry P. Rosen

Role of Cysteinyl Residues in Sensing Pb(II), Cd(II), and Zn(II) by the Plasmid pI258 CadC Repressor
J. Biol. Chem. 2001 276: 14955-14960. First Published on February 14, 2001; 10.1074/jbc.M010595200 [Abstract] [Full Text] [PDF]  

Ralff C. J. Ribeiro, Weijun Feng, Richard L. Wagner, Cláudia H. R. M. Costa, Alexandre C. Pereira, James W. Apriletti, Robert J. Fletterick, and John D. Baxter

Definition of the Surface in the Thyroid Hormone Receptor Ligand Binding Domain for Association as Homodimers and Heterodimers with Retinoid X Receptor
J. Biol. Chem. 2001 276: 14987-14995. First Published on January 5, 2001; 10.1074/jbc.M010195200 [Abstract] [Full Text] [PDF]  

Xu Feng, Yuan Jiang, Paul Meltzer, and Paul M. Yen

Transgenic Targeting of a Dominant Negative Corepressor to Liver Blocks Basal Repression by Thyroid Hormone Receptor and Increases Cell Proliferation
J. Biol. Chem. 2001 276: 15066-15072. [Abstract] [Full Text] [PDF]  

Xiaorong Liu and Carla B. Green

A Novel Promoter Element, Photoreceptor Conserved Element II, Directs Photoreceptor-specific Expression of Nocturnin in Xenopus laevis
J. Biol. Chem. 2001 276: 15146-15154. First Published on January 16, 2001; 10.1074/jbc.M009970200 [Abstract] [Full Text] [PDF]  

Nilanjan Ghosh, Ildiko Gyory, Gabriela Wright, Justin Wood, and Kenneth L. Wright

Positive Regulatory Domain I Binding Factor 1 Silences Class II Transactivator Expression in Multiple Myeloma Cells
J. Biol. Chem. 2001 276: 15264-15268. First Published on January 30, 2001; 10.1074/jbc.M100862200 [Abstract] [Full Text] [PDF]  

Alla V. Ivanova, Sergey V. Ivanov, Alla Danilkovitch-Miagkova, and Michael I. Lerman

Regulation of STRA13 by the von Hippel-Lindau Tumor Suppressor Protein, Hypoxia, and the UBC9/Ubiquitin Proteasome Degradation Pathway
J. Biol. Chem. 2001 276: 15306-15315. First Published on February 6, 2001; 10.1074/jbc.M010516200 [Abstract] [Full Text] [PDF]  

Marie O. Péquignot, Isabelle Desguerre, Runu Dey, Marzia Tartari, Massimo Zeviani, Alessandro Agostino, Chantal Benelli, Françoise Fouque, Carina Prip-Buus, Dominique Marchant, Marc Abitbol, and Cécile Marsac

New Splicing-site Mutations in the SURF1 Gene in Leigh Syndrome Patients
J. Biol. Chem. 2001 276: 15326-15329. First Published on February 6, 2001; 10.1074/jbc.M100388200 [Abstract] [Full Text] [PDF]  

Fajun Yang, Xiaoyu Li, Manju Sharma, Mark Zarnegar, Bing Lim, and Zijie Sun

Androgen Receptor Specifically Interacts with a Novel p21-activated Kinase, PAK6
J. Biol. Chem. 2001 276: 15345-15353. First Published on January 25, 2001; 10.1074/jbc.M010311200 [Abstract] [Full Text] [PDF]  

Michaël Perrais, Pascal Pigny, Marie-Pierre Buisine, Nicole Porchet, Jean-Pierre Aubert, and Isabelle Van Seuningen-Lempire

Aberrant Expression of Human Mucin Gene MUC5B in Gastric Carcinoma and Cancer Cells. IDENTIFICATION AND REGULATION OF A DISTAL PROMOTER
J. Biol. Chem. 2001 276: 15386-15396. First Published on January 30, 2001; 10.1074/jbc.M010534200 [Abstract] [Full Text] [PDF]  

Jude Beaudoin and Simon Labbé

The Fission Yeast Copper-sensing Transcription Factor Cuf1 Regulates the Copper Transporter Gene Expression through an Ace1/Amt1-like Recognition Sequence
J. Biol. Chem. 2001 276: 15472-15480. First Published on January 26, 2001; 10.1074/jbc.M011256200 [Abstract] [Full Text] [PDF]  

Maria M. Lopez, Katsuhide Yutani, and George I. Makhatadze

Interactions of the Cold Shock Protein CspB from Bacillus subtilis with Single-stranded DNA. IMPORTANCE OF THE T BASE CONTENT AND POSITION WITHIN THE TEMPLATE
J. Biol. Chem. 2001 276: 15511-15518. First Published on January 29, 2001; 10.1074/jbc.M010474200 [Abstract] [Full Text] [PDF]  

Eric R. Schuur, Lisa A. McPherson, George P. Yang, and Ronald J. Weigel

Genomic Structure of the Promoters of the Human Estrogen Receptor- Gene Demonstrate Changes in Chromatin Structure Induced by AP2
J. Biol. Chem. 2001 276: 15519-15526. First Published on February 2, 2001; 10.1074/jbc.M009001200 [Abstract] [Full Text] [PDF]  

RNA: Structure Metabolism and Catalysis:

Heather A. Meehan and Gregory J. Connell

The Hairpin Loop but Not the Bulged C of the Iron Responsive Element Is Essential for High Affinity Binding to Iron Regulatory Protein-1
J. Biol. Chem. 2001 276: 14791-14796. First Published on February 7, 2001; 10.1074/jbc.M010295200 [Abstract] [Full Text] [PDF]  

Yoshio Kato, Tomoko Kuwabara, Masaki Warashina, Hirofumi Toda, and Kazunari Taira

Relationships between the Activities in Vitro and in Vivo of Various Kinds of Ribozyme and Their Intracellular Localization in Mammalian Cells
J. Biol. Chem. 2001 276: 15378-15385. First Published on January 30, 2001; 10.1074/jbc.M010570200 [Abstract] [Full Text] [PDF]  

Protein Synthesis Post-Translation Modification and Degradation:

Jochen Walter, Regina Fluhrer, Bianka Hartung, Michael Willem, Christoph Kaether, Anja Capell, Sven Lammich, Gerd Multhaup, and Christian Haass

Phosphorylation Regulates Intracellular Trafficking of -Secretase
J. Biol. Chem. 2001 276: 14634-14641. First Published on January 29, 2001; 10.1074/jbc.M011116200 [Abstract] [Full Text] [PDF]  

Juliana Johnson Conkright, James P. Bridges, Cheng-Lun Na, Wim F. Voorhout, Bruce Trapnell, Stephan W. Glasser, and Timothy E. Weaver

Secretion of Surfactant Protein C, an Integral Membrane Protein, Requires the N-terminal Propeptide
J. Biol. Chem. 2001 276: 14658-14664. First Published on January 30, 2001; 10.1074/jbc.M011770200 [Abstract] [Full Text] [PDF]  

Johannes Schlöndorff, Lawrence Lum, and Carl P. Blobel

Biochemical and Pharmacological Criteria Define Two Shedding Activities for TRANCE/OPGL That Are Distinct from the Tumor Necrosis Factor Convertase
J. Biol. Chem. 2001 276: 14665-14674. First Published on January 30, 2001; 10.1074/jbc.M010741200 [Abstract] [Full Text] [PDF]  

Eulàlia de Nadal, Robert P. Fadden, Amparo Ruiz, Timothy Haystead, and Joaquín Ariño

A Role for the Ppz Ser/Thr Protein Phosphatases in the Regulation of Translation Elongation Factor 1B
J. Biol. Chem. 2001 276: 14829-14834. First Published on February 5, 2001; 10.1074/jbc.M010824200 [Abstract] [Full Text] [PDF]  

Sheri Uma, Bo-Geon Yun, and Robert L. Matts

The Heme-regulated Eukaryotic Initiation Factor 2 Kinase. A POTENTIAL REGULATORY TARGET FOR CONTROL OF PROTEIN SYNTHESIS BY DIFFUSIBLE GASES
J. Biol. Chem. 2001 276: 14875-14883. First Published on February 5, 2001; 10.1074/jbc.M011476200 [Abstract] [Full Text] [PDF]  

Nadia Normand, Hans van Leeuwen, and Peter O'Hare

Particle Formation by a Conserved Domain of the Herpes Simplex Virus Protein VP22 Facilitating Protein and Nucleic Acid Delivery
J. Biol. Chem. 2001 276: 15042-15050. First Published on January 18, 2001; 10.1074/jbc.M010294200 [Abstract] [Full Text] [PDF] Supplemental Data  

Anne-Marie Duchêne, Nemo Peeters, André Dietrich, Anne Cosset, Ian D. Small, and Henri Wintz

Overlapping Destinations for Two Dual Targeted Glycyl-tRNA Synthetases in Arabidopsis thaliana and Phaseolus vulgaris
J. Biol. Chem. 2001 276: 15275-15283. First Published on February 2, 2001; 10.1074/jbc.M011525200 [Abstract] [Full Text] [PDF]  

Protein Structure and Folding:

Chun-Rong Chen, Kunihiko Tanaka, Gregorio D. Chazenbalk, Sandra M. McLachlan, and Basil Rapoport

A Full Biological Response to Autoantibodies in Graves' Disease Requires a Disulfide-bonded Loop in the Thyrotropin Receptor N Terminus Homologous to a Laminin Epidermal Growth Factor-like Domain
J. Biol. Chem. 2001 276: 14767-14772. First Published on February 8, 2001; 10.1074/jbc.M008001200 [Abstract] [Full Text] [PDF]  

Alex Chapeaurouge, Jonas S. Johansson, and Sérgio T. Ferreira

Folding Intermediates of a Model Three-helix Bundle Protein. PRESSURE AND COLD DENATURATION STUDIES
J. Biol. Chem. 2001 276: 14861-14866. First Published on February 5, 2001; 10.1074/jbc.M009622200 [Abstract] [Full Text] [PDF]  

Yung-Jen Chuang, Richard Swanson, Srikumar M. Raja, and Steven T. Olson

Heparin Enhances the Specificity of Antithrombin for Thrombin and Factor Xa Independent of the Reactive Center Loop Sequence. EVIDENCE FOR AN EXOSITE DETERMINANT OF FACTOR Xa SPECIFICITY IN HEPARIN-ACTIVATED ANTITHROMBIN
J. Biol. Chem. 2001 276: 14961-14971. First Published on February 7, 2001; 10.1074/jbc.M011550200 [Abstract] [Full Text] [PDF]  

Kevin Lehman, C. Kiong Ho, and Stewart Shuman

Importance of Homodimerization for the in Vivo Function of Yeast RNA Triphosphatase
J. Biol. Chem. 2001 276: 14996-15002. First Published on February 1, 2001; 10.1074/jbc.M100588200 [Abstract] [Full Text] [PDF]  

Demetres D. Leonidas, Ester Boix, Robert Prill, Motoshi Suzuki, Richard Turton, Kathryn Minson, G. Jawahar Swaminathan, Richard J. Youle, and K. Ravi Acharya

Mapping the Ribonucleolytic Active Site of Eosinophil-derived Neurotoxin (EDN). HIGH RESOLUTION CRYSTAL STRUCTURES OF EDN COMPLEXES WITH ADENYLIC NUCLEOTIDE INHIBITORS
J. Biol. Chem. 2001 276: 15009-15017. First Published on January 11, 2001; 10.1074/jbc.M010585200 [Abstract] [Full Text] [PDF]  

Monique Gangloff, Marc Ruff, Sylvia Eiler, Sylvie Duclaud, Jean Marie Wurtz, and Dino Moras

Crystal Structure of a Mutant hER Ligand-binding Domain Reveals Key Structural Features for the Mechanism of Partial Agonism
J. Biol. Chem. 2001 276: 15059-15065. First Published on February 6, 2001; 10.1074/jbc.M009870200 [Abstract] [Full Text] [PDF]  

Songlin Li, Kenneth B. Taylor, Stephen J. Kelly, and Mark J. Jedrzejas

Vitamin C Inhibits the Enzymatic Activity of Streptococcus pneumoniae Hyaluronate Lyase
J. Biol. Chem. 2001 276: 15125-15130. First Published on January 12, 2001; 10.1074/jbc.M011102200 [Abstract] [Full Text] [PDF]  

James B. Thoden, Travis M. Wohlers, Judith L. Fridovich-Keil, and Hazel M. Holden

Human UDP-galactose 4-Epimerase. ACCOMMODATION OF UDP-N-ACETYLGLUCOSAMINE WITHIN THE ACTIVE SITE
J. Biol. Chem. 2001 276: 15131-15136. First Published on January 26, 2001; 10.1074/jbc.M100220200 [Abstract] [Full Text] [PDF]  

Anne Bergeron, Myreille D'Astous, David E. Timm, and Robert M. Tanguay

Structural and Functional Analysis of Missense Mutations in Fumarylacetoacetate Hydrolase, the Gene Deficient in Hereditary Tyrosinemia Type 1
J. Biol. Chem. 2001 276: 15225-15231. First Published on January 22, 2001; 10.1074/jbc.M009341200 [Abstract] [Full Text] [PDF]  

Tadahiro Goda, Minoru Funakoshi, Hiroto Suhara, Takeharu Nishimoto, and Hideki Kobayashi

The N-terminal Helix of Xenopus Cyclins A and B Contributes to Binding Specificity of the Cyclin-CDK Complex
J. Biol. Chem. 2001 276: 15415-15422. First Published on January 30, 2001; 10.1074/jbc.M011101200 [Abstract] [Full Text] [PDF]  

Motohiro Horiuchi, Gerald S. Baron, Liang-Wen Xiong, and Byron Caughey

Inhibition of Interactions and Interconversions of Prion Protein Isoforms by Peptide Fragments from the C-terminal Folded Domain
J. Biol. Chem. 2001 276: 15489-15497. First Published on February 1, 2001; 10.1074/jbc.M100288200 [Abstract] [Full Text] [PDF]  

Enzyme Catalysis and Regulation:

Keiko Kato, Tadaaki Kishi, Tomohiro Kamachi, Morito Akisada, Takuya Oka, Ryosuke Midorikawa, Koji Takio, Naoshi Dohmae, Phillip I. Bird, Jiuru Sun, Fiona Scott, Yoshimasa Miyake, Kazuhiko Yamamoto, Atsunori Machida, Tatsuya Tanaka, Kazumasa Matsumoto, Masao Shibata, and Sadao Shiosaka

Serine Proteinase Inhibitor 3 and Murinoglobulin I Are Potent Inhibitors of Neuropsin in Adult Mouse Brain
J. Biol. Chem. 2001 276: 14562-14571. First Published on February 5, 2001; 10.1074/jbc.M010725200 [Abstract] [Full Text] [PDF]  

Tan Wang, Andrew J. Piefer, and Colleen B. Jonsson

Interactions of the Human T-cell Leukemia Virus Type-II Integrase with the Conserved CA in the Retroviral Long Terminal Repeat End
J. Biol. Chem. 2001 276: 14710-14717. First Published on February 2, 2001; 10.1074/jbc.M007754200 [Abstract] [Full Text] [PDF]  

Lee-Ho Wang, Ah-Lim Tsai, and Pei-Yung Hsu

Substrate Binding Is the Rate-limiting Step in Thromboxane Synthase Catalysis
J. Biol. Chem. 2001 276: 14737-14743. First Published on January 31, 2001; 10.1074/jbc.M009177200 [Abstract] [Full Text] [PDF]  

John Lee, Michel Gravel, Enoch Gao, Ryan C. O'Neill, and Peter E. Braun

Identification of Essential Residues in 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase. CHEMICAL MODIFICATION AND SITE-DIRECTED MUTAGENESIS TO INVESTIGATE THE ROLE OF CYSTEINE AND HISTIDINE RESIDUES IN ENZYMATIC ACTIVITY
J. Biol. Chem. 2001 276: 14804-14813. First Published on February 5, 2001; 10.1074/jbc.M009434200 [Abstract] [Full Text] [PDF]  

Dung-Ho Wu, Guey-Yueh Shi, Woei-Jer Chuang, Jung-Mao Hsu, Kung-Chia Young, Chung-Wen Chang, and Hua-Lin Wu

Coiled Coil Region of Streptokinase -Domain Is Essential for Plasminogen Activation
J. Biol. Chem. 2001 276: 15025-15033. First Published on January 31, 2001; 10.1074/jbc.M005935200 [Abstract] [Full Text] [PDF]  

Douglas M. Swank, Marc L. Bartoo, Aileen F. Knowles, Cathryn Iliffe, Sanford I. Bernstein, Justin E. Molloy, and John C. Sparrow

Alternative Exon-encoded Regions of Drosophila Myosin Heavy Chain Modulate ATPase Rates and Actin Sliding Velocity
J. Biol. Chem. 2001 276: 15117-15124. First Published on December 27, 2000; 10.1074/jbc.M008379200 [Abstract] [Full Text] [PDF]  

Brian G. Miller, Mark J. Snider, Richard Wolfenden, and Steven A. Short

Dissecting a Charged Network at the Active Site of Orotidine-5'-phosphate Decarboxylase
J. Biol. Chem. 2001 276: 15174-15176. First Published on January 30, 2001; 10.1074/jbc.M011429200 [Abstract] [Full Text] [PDF]  

Jiuru Sun, James C. Whisstock, Patrick Harriott, Brian Walker, Andrea Novak, Philip E. Thompson, A. Ian Smith, and Phillip I. Bird

Importance of the P4' Residue in Human Granzyme B Inhibitors and Substrates Revealed by Scanning Mutagenesis of the Proteinase Inhibitor 9 Reactive Center Loop
J. Biol. Chem. 2001 276: 15177-15184. First Published on February 1, 2001; 10.1074/jbc.M006645200 [Abstract] [Full Text] [PDF]  

Raynard L. Bateman, P. Bhanumoorthy, John F. Witte, Ronald W. McClard, Markus Grompe, and David E. Timm

Mechanistic Inferences from the Crystal Structure of Fumarylacetoacetate Hydrolase with a Bound Phosphorus-based Inhibitor
J. Biol. Chem. 2001 276: 15284-15291. First Published on January 11, 2001; 10.1074/jbc.M007621200 [Abstract] [Full Text] [PDF]  

Metabolism and Bioenergetics:

R. Duncan Farrant, Valerie Walker, Graham A. Mills, John M. Mellor, and G. John Langley

Pyridoxal Phosphate De-activation by Pyrroline-5-carboxylic Acid. INCREASED RISK OF VITAMIN B₆ DEFICIENCY AND SEIZURES IN HYPERPROLINEMIA TYPE II
J. Biol. Chem. 2001 276: 15107-15116. First Published on December 29, 2000; 10.1074/jbc.M010860200 [Abstract] [Full Text] [PDF]  

Mikio Tanabe, Kazuaki Nishio, Yuko Iko, Yoshihiro Sambongi, Atsuko Iwamoto-Kihara, Yoh Wada, and Masamitsu Futai

Rotation of a Complex of the Subunit and c Ring of Escherichia coli ATP Synthase. THE ROTOR AND STATOR ARE INTERCHANGEABLE
J. Biol. Chem. 2001 276: 15269-15274. First Published on February 13, 2001; 10.1074/jbc.M100289200 [Abstract] [Full Text] [PDF]  

Deirdre L. Vaden, Daobin Ding, Brian Peterson, and Miriam L. Greenberg

Lithium and Valproate Decrease Inositol Mass and Increase Expression of the Yeast INO1 and INO2 Genes for Inositol Biosynthesis
J. Biol. Chem. 2001 276: 15466-15471. First Published on January 22, 2001; 10.1074/jbc.M004179200 [Abstract] [Full Text] [PDF]  

Glycobiology and Extracellular Matrices:

Arun K. Datta, Roger Chammas, and James C. Paulson

Conserved Cysteines in the Sialyltransferase Sialylmotifs Form an Essential Disulfide Bond
J. Biol. Chem. 2001 276: 15200-15207. First Published on January 29, 2001; 10.1074/jbc.M010542200 [Abstract] [Full Text] [PDF]  

Yohei Maeshima, Mark Manfredi, Corinne Reimer, Kathryn A. Holthaus, Helmut Hopfer, Babi R. Chandamuri, Surender Kharbanda, and Raghu Kalluri

Identification of the Anti-angiogenic Site within Vascular Basement Membrane-derived Tumstatin
J. Biol. Chem. 2001 276: 15240-15248. First Published on February 7, 2001; 10.1074/jbc.M007764200 [Abstract] [Full Text] [PDF]  

Kiyohiko Angata, Ten-Yang Yen, Assou El-Battari, Bruce A. Macher, and Minoru Fukuda

Unique Disulfide Bond Structures Found in ST8Sia IV Polysialyltransferase Are Required for Its Activity
J. Biol. Chem. 2001 276: 15369-15377. First Published on February 7, 2001; 10.1074/jbc.M100576200 [Abstract] [Full Text] [PDF]  

Elizabeth Hahn-Dantona, Jose F. Ruiz, Paul Bornstein, and Dudley K. Strickland

The Low Density Lipoprotein Receptor-related Protein Modulates Levels of Matrix Metalloproteinase 9 (MMP-9) by Mediating Its Cellular Catabolism
J. Biol. Chem. 2001 276: 15498-15503. First Published on February 2, 2001; 10.1074/jbc.M100121200 [Abstract] [Full Text] [PDF]  

Gene Wijffels, Craig Eisemann, George Riding, Roger Pearson, Alun Jones, Peter Willadsen, and Ross Tellam

A Novel Family of Chitin-binding Proteins from Insect Type 2 Peritrophic Matrix. cDNA SEQUENCES, CHITIN BINDING ACTIVITY, AND CELLULAR LOCALIZATION
J. Biol. Chem. 2001 276: 15527-15536. First Published on February 1, 2001; 10.1074/jbc.M009393200 [Abstract] [Full Text] [PDF]  

Lipids and Lipoproteins:

Xiang Fang, Terry L. Kaduce, Neal L. Weintraub, Shawn Harmon, Lynn M. Teesch, Christophe Morisseau, David A. Thompson, Bruce D. Hammock, and Arthur A. Spector

Pathways of Epoxyeicosatrienoic Acid Metabolism in Endothelial Cells. IMPLICATIONS FOR THE VASCULAR EFFECTS OF SOLUBLE EPOXIDE HYDROLASE INHIBITION
J. Biol. Chem. 2001 276: 14867-14874. First Published on February 7, 2001; 10.1074/jbc.M011761200 [Abstract] [Full Text] [PDF]  

Laura L. Listenberger, Daniel S. Ory, and Jean E. Schaffer

Palmitate-induced Apoptosis Can Occur through a Ceramide-independent Pathway
J. Biol. Chem. 2001 276: 14890-14895. First Published on February 13, 2001; 10.1074/jbc.M010286200 [Abstract] [Full Text] [PDF]  

Gilles Lambert, Naohiko Sakai, Boris L. Vaisman, Edward B. Neufeld, Benoit Marteyn, Chi-Chao Chan, Beverly Paigen, Enrico Lupia, Alton Thomas, Liliane J. Striker, Joan Blanchette-Mackie, Gyorgy Csako, John N. Brady, Rene Costello, Gary E. Striker, Alan T. Remaley, H. Bryan Brewer, Jr., and Silvia Santamarina-Fojo

Analysis of Glomerulosclerosis and Atherosclerosis in Lecithin Cholesterol Acyltransferase-deficient Mice
J. Biol. Chem. 2001 276: 15090-15098. First Published on February 7, 2001; 10.1074/jbc.M008466200 [Abstract] [Full Text] [PDF]  

Michael L. Fitzgerald, Armando J. Mendez, Kathryn J. Moore, Lorna P. Andersson, Hess A. Panjeton, and Mason W. Freeman

ATP-binding Cassette Transporter A1 Contains an NH₂-terminal Signal Anchor Sequence That Translocates the Protein's First Hydrophilic Domain to the Exoplasmic Space
J. Biol. Chem. 2001 276: 15137-15145. [Abstract] [Full Text] [PDF]  

Yuka Kimura, Anja Schmitt, Nobuyuki Fukushima, Isao Ishii, Hideo Kimura, Angel R. Nebreda, and Jerold Chun

Two Novel Xenopus Homologs of Mammalian LP_A1/EDG-2 Function as Lysophosphatidic Acid Receptors in Xenopus Oocytes and Mammalian Cells
J. Biol. Chem. 2001 276: 15208-15215. First Published on February 5, 2001; 10.1074/jbc.M011588200 [Abstract] [Full Text] [PDF]  

Membrane Transport Structure Function and Biogenesis:

Cheryl A. Woolhead, Alexandra Mant, Soo Jung Kim, Colin Robinson, and Alison Rodger

Conformation of a Purified "Spontaneously" Inserting Thylakoid Membrane Protein Precursor in Aqueous Solvent and Detergent Micelles
J. Biol. Chem. 2001 276: 14607-14613. First Published on January 16, 2001; 10.1074/jbc.M009600200 [Abstract] [Full Text] [PDF]  

Alexander Zitzer, Robert Bittman, Christopher A. Verbicky, Ravi K. Erukulla, Sucharit Bhakdi, Silvia Weis, Angela Valeva, and Michael Palmer

Coupling of Cholesterol and Cone-shaped Lipids in Bilayers Augments Membrane Permeabilization by the Cholesterol-specific Toxins Streptolysin O and Vibrio cholerae Cytolysin
J. Biol. Chem. 2001 276: 14628-14633. First Published on February 2, 2001; 10.1074/jbc.M100241200 [Abstract] [Full Text] [PDF]  

Christoph Sauvant, Hildegard Holzinger, and Michael Gekle

Modulation of the Basolateral and Apical Step of Transepithelial Organic Anion Secretion in Proximal Tubular Opossum Kidney Cells. ACUTE EFFECTS OF EPIDERMAL GROWTH FACTOR AND MITOGEN-ACTIVATED PROTEIN KINASE
J. Biol. Chem. 2001 276: 14695-14703. First Published on February 2, 2001; 10.1074/jbc.M007046200 [Abstract] [Full Text] [PDF]  

Angela Valeva, Ronny Schnabel, Iwan Walev, Fatima Boukhallouk, Sucharit Bhakdi, and Michael Palmer

Membrane Insertion of the Heptameric Staphylococcal -Toxin Pore. A DOMINO-LIKE STRUCTURAL TRANSITION THAT IS ALLOSTERICALLY MODULATED BY THE TARGET CELL MEMBRANE
J. Biol. Chem. 2001 276: 14835-14841. First Published on February 2, 2001; 10.1074/jbc.M100301200 [Abstract] [Full Text] [PDF]  

Marcus M. Hämmerle, Andrei A. Aleksandrov, and John R. Riordan

Disease-associated Mutations in the Extracytoplasmic Loops of Cystic Fibrosis Transmembrane Conductance Regulator Do Not Impede Biosynthetic Processing but Impair Chloride Channel Stability
J. Biol. Chem. 2001 276: 14848-14854. First Published on February 6, 2001; 10.1074/jbc.M011017200 [Abstract] [Full Text] [PDF]  

Lin-Hua Jiang, François Rassendren, Valeria Spelta, Annmarie Surprenant, and R. Alan North

Amino Acid Residues Involved in Gating Identified in the First Membrane-spanning Domain of the Rat P2X₂ Receptor
J. Biol. Chem. 2001 276: 14902-14908. First Published on February 6, 2001; 10.1074/jbc.M011327200 [Abstract] [Full Text] [PDF]  

Tip W. Loo and David M. Clarke

Defining the Drug-binding Site in the Human Multidrug Resistance P-glycoprotein Using a Methanethiosulfonate Analog of Verapamil, MTS-verapamil
J. Biol. Chem. 2001 276: 14972-14979. First Published on February 14, 2001; 10.1074/jbc.M100407200 [Abstract] [Full Text] [PDF]  

André T. J. Klein, Phil Barnett, Gina Bottger, Daphne Konings, Henk F. Tabak, and Ben Distel

Recognition of Peroxisomal Targeting Signal Type 1 by the Import Receptor Pex5p
J. Biol. Chem. 2001 276: 15034-15041. First Published on January 11, 2001; 10.1074/jbc.M010776200 [Abstract] [Full Text] [PDF]  

Zhongsen Zhang, David Lewis, Carlota Sumbilla, Giuseppe Inesi, and Chikashi Toyoshima

The Role of the M6-M7 Loop (L67) in Stabilization of the Phosphorylation and Ca²⁺ Binding Domains of the Sarcoplasmic Reticulum Ca²⁺-ATPase (SERCA)
J. Biol. Chem. 2001 276: 15232-15239. First Published on February 5, 2001; 10.1074/jbc.M010813200 [Abstract] [Full Text] [PDF]  

Mitsuko Hayashi, Shinya Taniguchi, Yuki Ishizuka, Hye-Sook Kim, Yusuke Wataya, Akitsugu Yamamoto, and Yoshinori Moriyama

A Homologue of N-Ethylmaleimide-sensitive Factor in the Malaria Parasite Plasmodium falciparum Is Exported and Localized in Vesicular Structures in the Cytoplasm of Infected Erythrocytes in the Brefeldin A-sensitive Pathway
J. Biol. Chem. 2001 276: 15249-15255. First Published on February 1, 2001; 10.1074/jbc.M011709200 [Abstract] [Full Text] [PDF]  

Susanne Nyfeler, Karin Senn, and Christoph Kempf

Expression of Semliki Forest Virus E1 Protein in Escherichia coli. LOW pH-INDUCED PORE FORMATION
J. Biol. Chem. 2001 276: 15453-15457. First Published on February 13, 2001; 10.1074/jbc.M011061200 [Abstract] [Full Text] [PDF]  

Mechanisms Of Signal Transduction:

Yiguo Zhang, Shuping Zhong, Ziming Dong, Nanyue Chen, Ann M. Bode, Wei-ya Ma, and Zigang Dong

UVA Induces Ser³⁸¹ Phosphorylation of p90^RSK/MAPKAP-K1 via ERK and JNK Pathways
J. Biol. Chem. 2001 276: 14572-14580. First Published on January 31, 2001; 10.1074/jbc.M004615200 [Abstract] [Full Text] [PDF]  

José Esparza-López, José Luis Montiel, M. Magdalena Vilchis-Landeros, Toshihide Okadome, Kohei Miyazono, and Fernando López-Casillas

Ligand Binding and Functional Properties of Betaglycan, a Co-receptor of the Transforming Growth Factor- Superfamily. SPECIALIZED BINDING REGIONS FOR TRANSFORMING GROWTH FACTOR- AND INHIBIN A
J. Biol. Chem. 2001 276: 14588-14596. First Published on February 5, 2001; 10.1074/jbc.M008866200 [Abstract] [Full Text] [PDF]  

Micah A. Luftig, Ellen Cahir-McFarland, George Mosialos, and Elliott Kieff

Effects of the NIK aly Mutation on NF-B Activation by the Epstein-Barr Virus Latent Infection Membrane Protein, Lymphotoxin Receptor, and CD40
J. Biol. Chem. 2001 276: 14602-14606. First Published on March 14, 2001; 10.1074/jbc.C100103200 [Abstract] [Full Text] [PDF]  

Ruediger Arnold, Jen Liou, Hannes C. A. Drexler, Arthur Weiss, and Friedemann Kiefer

Caspase-mediated Cleavage of Hematopoietic Progenitor Kinase 1 (HPK1) Converts an Activator of NFB into an Inhibitor of NFB
J. Biol. Chem. 2001 276: 14675-14684. First Published on January 29, 2001; 10.1074/jbc.M008343200 [Abstract] [Full Text] [PDF]  

Martin Zabe and William L. Dean

Plasma Membrane Ca²⁺-ATPase Associates with the Cytoskeleton in Activated Platelets through a PDZ-binding Domain
J. Biol. Chem. 2001 276: 14704-14709. First Published on February 1, 2001; 10.1074/jbc.M009850200 [Abstract] [Full Text] [PDF]  

Bing Su, Jinke Cheng, Jianhua Yang, and Zijian Guo

MEKK2 Is Required for T-cell Receptor Signals in JNK Activation and Interleukin-2 Gene Expression
J. Biol. Chem. 2001 276: 14784-14790. First Published on February 6, 2001; 10.1074/jbc.M010134200 [Abstract] [Full Text] [PDF]  

Michael Poteser, Christoph Romanin, Wolfgang Schreibmayer, Bernd Mayer, and Klaus Groschner

S-Nitrosation Controls Gating and Conductance of the 1 Subunit of Class C L-type Ca²⁺ Channels
J. Biol. Chem. 2001 276: 14797-14803. First Published on February 7, 2001; 10.1074/jbc.M008244200 [Abstract] [Full Text] [PDF]  

Tsui-Ting Ching, Ao-Lin Hsu, Amy J. Johnson, and Ching-Shih Chen

Phosphoinositide 3-Kinase Facilitates Antigen-stimulated Ca²⁺ Influx in RBL-2H3 Mast Cells via a Phosphatidylinositol 3,4,5-Trisphosphate-sensitive Ca²⁺ Entry Mechanism
J. Biol. Chem. 2001 276: 14814-14820. First Published on February 5, 2001; 10.1074/jbc.M009851200 [Abstract] [Full Text] [PDF]  

James M. Nelson and David W. Fry

Akt, MAPK (Erk1/2), and p38 Act in Concert to Promote Apoptosis in Response to ErbB Receptor Family Inhibition
J. Biol. Chem. 2001 276: 14842-14847. First Published on February 7, 2001; 10.1074/jbc.M008786200 [Abstract] [Full Text] [PDF]  

Sherri L. Rogalski and Charles Chavkin

Eicosanoids Inhibit the G-protein-gated Inwardly Rectifying Potassium Channel (Kir3) at the Na⁺/PIP₂ Gating Site
J. Biol. Chem. 2001 276: 14855-14860. First Published on February 7, 2001; 10.1074/jbc.M010097200 [Abstract] [Full Text] [PDF]  

Mario D. Galigniana, Christine Radanyi, Jack-Michel Renoir, Paul R. Housley, and William B. Pratt

Evidence That the Peptidylprolyl Isomerase Domain of the hsp90-binding Immunophilin FKBP52 Is Involved in Both Dynein Interaction and Glucocorticoid Receptor Movement to the Nucleus
J. Biol. Chem. 2001 276: 14884-14889. First Published on February 13, 2001; 10.1074/jbc.M010809200 [Abstract] [Full Text] [PDF]  

Tracy Mourton, Carina B. Hellberg, Susan M. Burden-Gulley, Jason Hinman, Amy Rhee, and Susann M. Brady-Kalnay

The PTPµ Protein-tyrosine Phosphatase Binds and Recruits the Scaffolding Protein RACK1 to Cell-Cell Contacts
J. Biol. Chem. 2001 276: 14896-14901. First Published on February 13, 2001; 10.1074/jbc.M010823200 [Abstract] [Full Text] [PDF]  

Jonathan D. Graves, Kevin E. Draves, Yukiko Gotoh, Edwin G. Krebs, and Edward A. Clark

Both Phosphorylation and Caspase-mediated Cleavage Contribute to Regulation of the Ste20-like Protein Kinase Mst1 during CD95/Fas-induced Apoptosis
J. Biol. Chem. 2001 276: 14909-14915. First Published on February 13, 2001; 10.1074/jbc.M010905200 [Abstract] [Full Text] [PDF]  

Douglas D. Bannerman, Joan C. Tupper, William A. Ricketts, C. Frank Bennett, Robert K. Winn, and John M. Harlan

A Constitutive Cytoprotective Pathway Protects Endothelial Cells from Lipopolysaccharide-induced Apoptosis
J. Biol. Chem. 2001 276: 14924-14932. First Published on February 14, 2001; 10.1074/jbc.M100819200 [Abstract] [Full Text] [PDF]  

E. Robert McDonald, III, Patricia C. Chui, Peter F. Martelli, David T. Dicker, and Wafik S. El-Deiry

Death Domain Mutagenesis of KILLER/DR5 Reveals Residues Critical for Apoptotic Signaling
J. Biol. Chem. 2001 276: 14939-14945. First Published on February 13, 2001; 10.1074/jbc.M100399200 [Abstract] [Full Text] [PDF]  

Aimin Xu, Yu Wang, Lance Yi Xu, and R. Stewart Gilmour

Protein Kinase C -mediated Negative Feedback Regulation Is Responsible for the Termination of Insulin-like Growth Factor I-induced Activation of Nuclear Phospholipase C 1 in Swiss 3T3 Cells
J. Biol. Chem. 2001 276: 14980-14986. First Published on February 14, 2001; 10.1074/jbc.M009144200 [Abstract] [Full Text] [PDF]  

Jeremy G. Richman, Ashley E. Brady, Qin Wang, Jennifer L. Hensel, Roger J. Colbran, and Lee E. Limbird

Agonist-regulated Interaction between ₂-Adrenergic Receptors and Spinophilin
J. Biol. Chem. 2001 276: 15003-15008. First Published on January 11, 2001; 10.1074/jbc.M011679200 [Abstract] [Full Text] [PDF]  

Andra S. Stevenson, Maria F. Gomez, David C. Hill-Eubanks, and Mark T. Nelson

NFAT4 Movement in Native Smooth Muscle. A ROLE FOR DIFFERENTIAL Ca²⁺ SIGNALING
J. Biol. Chem. 2001 276: 15018-15024. First Published on February 7, 2001; 10.1074/jbc.M011684200 [Abstract] [Full Text] [PDF]  

Masaru Tanaka, Keita Kirito, Yoshifumi Kashii, Mie Uchida, Tomoko Watanabe, Hitoshi Endo, Tomoyuki Endoh, Ken-ichi Sawada, Keiya Ozawa, and Norio Komatsu

Forkhead Family Transcription Factor FKHRL1 Is Expressed in Human Megakaryocytes. REGULATION OF CELL CYCLING AS A DOWNSTREAM MOLECULE OF THROMBOPOIETIN SIGNALING
J. Biol. Chem. 2001 276: 15082-15089. First Published on February 13, 2001; 10.1074/jbc.M007958200 [Abstract] [Full Text] [PDF]  

Yasuo Oshima and Raj K. Puri

Characterization of a Powerful High Affinity Antagonist That Inhibits Biological Activities of Human Interleukin-13
J. Biol. Chem. 2001 276: 15185-15191. First Published on January 26, 2001; 10.1074/jbc.M010159200 [Abstract] [Full Text] [PDF]  

Mei Cong, Stephen J. Perry, Fang-Tsyr Lin, Iain D. Fraser, Liaoyuan A. Hu, Wei Chen, Julie A. Pitcher, John D. Scott, and Robert J. Lefkowitz

Regulation of Membrane Targeting of the G Protein-coupled Receptor Kinase 2 by Protein Kinase A and Its Anchoring Protein AKAP79
J. Biol. Chem. 2001 276: 15192-15199. First Published on January 22, 2001; 10.1074/jbc.M009130200 [Abstract] [Full Text] [PDF]  

Tetsuya Noguchi, Masahiro Tsuda, Hitoshi Takeda, Toshiyuki Takada, Kenjiro Inagaki, Takuji Yamao, Kaoru Fukunaga, Takashi Matozaki, and Masato Kasuga

Inhibition of Cell Growth and Spreading by Stomach Cancer-associated Protein-tyrosine Phosphatase-1 (SAP-1) through Dephosphorylation of p130^cas
J. Biol. Chem. 2001 276: 15216-15224. First Published on February 14, 2001; 10.1074/jbc.M007208200 [Abstract] [Full Text] [PDF]  

Fanny Jaulin-Bastard, Hiroko Saito, André Le Bivic, Vincent Ollendorff, Sylvie Marchetto, Daniel Birnbaum, and Jean-Paul Borg

The ERBB2/HER2 Receptor Differentially Interacts with ERBIN and PICK1 PSD-95/DLG/ZO-1 Domain Proteins
J. Biol. Chem. 2001 276: 15256-15263. First Published on February 5, 2001; 10.1074/jbc.M010032200 [Abstract] [Full Text] [PDF]  

Satoshi Shigematsu, Sarah L. Miller, and Jeffrey E. Pessin

Differentiated 3T3L1 Adipocytes Are Composed of Heterogenous Cell Populations with Distinct Receptor Tyrosine Kinase Signaling Properties
J. Biol. Chem. 2001 276: 15292-15297. First Published on February 5, 2001; 10.1074/jbc.M009684200 [Abstract] [Full Text] [PDF]  

Hidekazu Yasui, Hironori Katoh, Yoshiaki Yamaguchi, Junko Aoki, Hirotada Fujita, Kazutoshi Mori, and Manabu Negishi

Differential Responses to Nerve Growth Factor and Epidermal Growth Factor in Neurite Outgrowth of PC12 Cells Are Determined by Rac1 Activation Systems
J. Biol. Chem. 2001 276: 15298-15305. First Published on January 31, 2001; 10.1074/jbc.M008546200 [Abstract] [Full Text] [PDF]  

Anne-Hélène Lagrue-Lak-Hal, Najet Debili, Gillian Kingbury, Christelle Lecut, Jean-Pierre Le Couedic, Jean-Luc Villeval, Martine Jandrot-Perrus, and William Vainchenker

Expression and Function of the Collagen Receptor GPVI during Megakaryocyte Maturation
J. Biol. Chem. 2001 276: 15316-15325. First Published on January 16, 2001; 10.1074/jbc.M009117200 [Abstract] [Full Text] [PDF]  

Jose van der Wal, Ron Habets, Péter Várnai, Tamas Balla, and Kees Jalink

Monitoring Agonist-induced Phospholipase C Activation in Live Cells by Fluorescence Resonance Energy Transfer
J. Biol. Chem. 2001 276: 15337-15344. First Published on January 10, 2001; 10.1074/jbc.M007194200 [Abstract] [Full Text] [PDF]  

Julia Billiard, Yutaka Umayahara, Kristine Wiren, Michael Centrella, Thomas L. McCarthy, and Peter Rotwein

Regulated Nuclear-Cytoplasmic Localization of CCAAT/ Enhancer-binding Protein in Osteoblasts
J. Biol. Chem. 2001 276: 15354-15361. First Published on January 30, 2001; 10.1074/jbc.M009973200 [Abstract] [Full Text] [PDF]  

Xing Shen, Jianming Li, Patrick Pei-chih Hu, David Waddell, Ji Zhang, and Xiao-Fan Wang

The Activity of Guanine Exchange Factor NET1 Is Essential for Transforming Growth Factor--mediated Stress Fiber Formation
J. Biol. Chem. 2001 276: 15362-15368. First Published on February 2, 2001; 10.1074/jbc.M009534200 [Abstract] [Full Text] [PDF]  

Minoru Narita, Hirokazu Mizoguchi, Tomohiko Suzuki, Michiko Narita, Nae J. Dun, Satoshi Imai, Yoshinori Yajima, Hiroshi Nagase, Tsutomu Suzuki, and Leon F. Tseng

Enhanced µ-Opioid Responses in the Spinal Cord of Mice Lacking Protein Kinase C Isoform
J. Biol. Chem. 2001 276: 15409-15414. First Published on January 29, 2001; 10.1074/jbc.M009716200 [Abstract] [Full Text] [PDF]  

Eduardo G. A. Cafferata, Anatilde M. González Guerrico, Omar H. Pivetta, and Tomás A. Santa-Coloma

NF-B Activation Is Involved in Regulation of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) by Interleukin-1
J. Biol. Chem. 2001 276: 15441-15444. First Published on February 5, 2001; 10.1074/jbc.M010061200 [Abstract] [Full Text] [PDF]  

Sarah A. Sagi, Tammy M. Seasholtz, Mariya Kobiashvili, Brenda A. Wilson, Deniz Toksoz, and Joan Heller Brown

Physical and Functional Interactions of G_q with Rho and Its Exchange Factors
J. Biol. Chem. 2001 276: 15445-15452. First Published on February 6, 2001; 10.1074/jbc.M008961200 [Abstract] [Full Text] [PDF]  

Jessica L. Lewis, Min Dong, Cynthia A. Earles, and Edwin R. Chapman

The Transmembrane Domain of Syntaxin 1A Is Critical for Cytoplasmic Domain Protein-Protein Interactions
J. Biol. Chem. 2001 276: 15458-15465. First Published on February 9, 2001; 10.1074/jbc.M011687200 [Abstract] [Full Text] [PDF]  

Mayank Srivastava, Nihal Ahmad, Sanjay Gupta, and Hasan Mukhtar

Involvement of Bcl-2 and Bax in Photodynamic Therapy-mediated Apoptosis. ANTISENSE Bcl-2 OLIGONUCLEOTIDE SENSITIZES RIF 1 CELLS TO PHOTODYNAMIC THERAPY APOPTOSIS
J. Biol. Chem. 2001 276: 15481-15488. First Published on January 31, 2001; 10.1074/jbc.M006920200 [Abstract] [Full Text] [PDF]  

Orla P. Barry, Brian Mullan, Dyane Sheehan, Marcelo G. Kazanietz, Fergus Shanahan, J. Kevin Collins, and Gerald C. O'Sullivan

Constitutive ERK1/2 Activation in Esophagogastric Rib Bone Marrow Micrometastatic Cells Is MEK-independent
J. Biol. Chem. 2001 276: 15537-15546. First Published on January 31, 2001; 10.1074/jbc.M010847200 [Abstract] [Full Text] [PDF]  

Vicky T. Estrera, Dung-Tsa Chen, Weiping Luo, Douglas C. Hixson, and Sue-Hwa Lin

Signal Transduction by the CEACAM1 Tumor Suppressor. PHOSPHORYLATION OF SERINE 503 IS REQUIRED FOR GROWTH-INHIBITORY ACTIVITY
J. Biol. Chem. 2001 276: 15547-15553. First Published on February 5, 2001; 10.1074/jbc.M008156200 [Abstract] [Full Text] [PDF]  

Tushar B. Deb, Leon Su, Lily Wong, Ezio Bonvini, Alan Wells, Michael David, and Gibbes R. Johnson

Epidermal Growth Factor (EGF) Receptor Kinase-independent Signaling by EGF
J. Biol. Chem. 2001 276: 15554-15560. First Published on February 5, 2001; 10.1074/jbc.M100928200 [Abstract] [Full Text] [PDF]  

Molecular Basis Of Cell and Developmental Biology:

Chafen Lu, Junichi Takagi, and Timothy A. Springer

Association of the Membrane Proximal Regions of the and Subunit Cytoplasmic Domains Constrains an Integrin in the Inactive State
J. Biol. Chem. 2001 276: 14642-14648. First Published on January 30, 2001; 10.1074/jbc.M100600200 [Abstract] [Full Text] [PDF]  

Shin Akakura, Minoru Yoshida, Yoshihiro Yoneda, and Sueharu Horinouchi

A Role for Hsc70 in Regulating Nucleocytoplasmic Transport of a Temperature-sensitive p53 (p53^Val-135)
J. Biol. Chem. 2001 276: 14649-14657. First Published on January 31, 2001; 10.1074/jbc.M100200200 [Abstract] [Full Text] [PDF]  

Thierry Vincent, Michel Jourdan, Man-Sun Sy, Bernard Klein, and Nadir Mechti

Hyaluronic Acid Induces Survival and Proliferation of Human Myeloma Cells through an Interleukin-6-mediated Pathway Involving the Phosphorylation of Retinoblastoma Protein
J. Biol. Chem. 2001 276: 14728-14736. First Published on January 29, 2001; 10.1074/jbc.M003965200 [Abstract] [Full Text] [PDF]  

Catherine E. Napper, Mark H. Dyson, and Maureen E. Taylor

An Extended Conformation of the Macrophage Mannose Receptor
J. Biol. Chem. 2001 276: 14759-14766. First Published on February 8, 2001; 10.1074/jbc.M100425200 [Abstract] [Full Text] [PDF]  

Hong Zhou, Vicky Kartsogiannis, Yun Shan Hu, Jan Elliott, Julian M. W. Quinn, William J. McKinstry, Matthew T. Gillespie, and Kong Wah Ng

A Novel Osteoblast-derived C-type Lectin That Inhibits Osteoclast Formation
J. Biol. Chem. 2001 276: 14916-14923. First Published on February 13, 2001; 10.1074/jbc.M011554200 [Abstract] [Full Text] [PDF]  

Janet van Adelsberg, Swati Sehgal, Andrew Kukes, Christopher Brady, Jonathan Barasch, Jun Yang, and Yonghong Huan

Activation of Hepatocyte Growth Factor (HGF) by Endogenous HGF Activator Is Required for Metanephric Kidney Morphogenesis in Vitro
J. Biol. Chem. 2001 276: 15099-15106. First Published on October 13, 2000; 10.1074/jbc.M006634200 [Abstract] [Full Text] [PDF]  

Sabrina Strano, Eliana Munarriz, Mario Rossi, Luisa Castagnoli, Yosef Shaul, Ada Sacchi, Moshe Oren, Marius Sudol, Gianni Cesareni, and Giovanni Blandino

Physical Interaction with Yes-associated Protein Enhances p73 Transcriptional Activity
J. Biol. Chem. 2001 276: 15164-15173. First Published on January 24, 2001; 10.1074/jbc.M010484200 [Abstract] [Full Text] [PDF]  

Konstantin V. Korotkov, Easwari Kumaraswamy, You Zhou, Dolph L. Hatfield, and Vadim N. Gladyshev

Association between the 15-kDa Selenoprotein and UDP-glucose:Glycoprotein Glucosyltransferase in the Endoplasmic Reticulum of Mammalian Cells
J. Biol. Chem. 2001 276: 15330-15336. First Published on February 7, 2001; 10.1074/jbc.M009861200 [Abstract] [Full Text] [PDF]  

Haiyoung Jung, Taenam Kim, Ho Zoon Chae, Kyong-Tai Kim, and Hyunjung Ha

Regulation of Macrophage Migration Inhibitory Factor and Thiol-specific Antioxidant Protein PAG by Direct Interaction
J. Biol. Chem. 2001 276: 15504-15510. First Published on January 31, 2001; 10.1074/jbc.M009620200 [Abstract] [Full Text] [PDF]  

Additions and Corrections:

Brian D. Bennett, Paul Denis, Mitsuru Haniu, David B. Teplow, Steve Kahn, Jean-Claude Louis, Martin Citron, and Robert Vassar

A furin-like convertase mediates propeptide cleavage of BACE, the Alzheimer's -secretase.
J. Biol. Chem. 2001 276: 15561. [Full Text] [PDF]  

Gerald M. Wilson, Kristina Sutphen, Keng-yu Chuang, and Gary Brewer

Folding of A+U-rich RNA elements modulates AUF1 binding. Potential roles in regulation of mRNA turnover.
J. Biol. Chem. 2001 276: 15562. [Full Text] [PDF]  

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