The cystic fibrosis transmembrane conductance regulator (CFTR) is a tightly regulated chloride channel of chloride-secreting or -reabsorbing epithelial cells. Mutations in CFTR are linked to cystic fibrosis. C-terminal truncations of CFTR strongly affect processing of the protein. The cover figure shows the influence of those truncations on the localization of CFTR in stably transfected BHK-21 cells. Details can be found in the article by Gentzsch and Riordan, pages 1291-1298. 1291.