Minireviews:

Martha S. Cyert

Regulation of Nuclear Localization during Signaling
J. Biol. Chem. 2001 276: 20805-20808. First Published on April 12, 2001; doi:10.1074/jbc.R100012200 [Full Text] [PDF]  

Accelerated Publications:

Mariam Dohadwala, Jie Luo, Li Zhu, Ying Lin, Graeme J. Dougherty, Sherven Sharma, Min Huang, Mehis Põld, Raj K. Batra, and Steven M. Dubinett

Non-small Cell Lung Cancer Cyclooxygenase-2-dependent Invasion Is Mediated by CD44
J. Biol. Chem. 2001 276: 20809-20812. First Published on April 24, 2001; doi:10.1074/jbc.C100140200 [Abstract] [Full Text] [PDF]  

Keiji Seno, Mika Kishimoto, Masayoshi Abe, Yusuke Higuchi, Masanori Mieda, Yuko Owada, Wataru Yoshiyama, Han Liu, and Fumio Hayashi

Light- and Guanosine 5'-3-O-(Thio)triphosphate-sensitive Localization of a G Protein and Its Effector on Detergent-resistant Membrane Rafts in Rod Photoreceptor Outer Segments
J. Biol. Chem. 2001 276: 20813-20816. First Published on April 23, 2001; doi:10.1074/jbc.C100032200 [Abstract] [Full Text] [PDF]  

Olena K. Vatamaniuk, Elizabeth A. Bucher, James T. Ward, and Philip A. Rea

A New Pathway for Heavy Metal Detoxification in Animals. PHYTOCHELATIN SYNTHASE IS REQUIRED FOR CADMIUM TOLERANCE IN CAENORHABDITIS ELEGANS
J. Biol. Chem. 2001 276: 20817-20820. First Published on April 19, 2001; doi:10.1074/jbc.C100152200 [Abstract] [Full Text] [PDF]  

Byoung-Chul Lee, Paula A. Croonquist, Tobin R. Sosnick, and Wouter D. Hoff

PAS Domain Receptor Photoactive Yellow Protein Is Converted to a Molten Globule State upon Activation
J. Biol. Chem. 2001 276: 20821-20823. First Published on April 23, 2001; doi:10.1074/jbc.C100106200 [Abstract] [Full Text] [PDF]  

Shuetsu Fukushi, Masato Okada, Joachim Stahl, Tsutomu Kageyama, Fuminori B. Hoshino, and Kazuhiko Katayama

Ribosomal Protein S5 Interacts with the Internal Ribosomal Entry Site of Hepatitis C Virus
J. Biol. Chem. 2001 276: 20824-20826. First Published on April 30, 2001; doi:10.1074/jbc.C100206200 [Abstract] [Full Text] [PDF]  

Nickolai O. Dulin, Jiaxin Niu, Darren D. Browning, Richard D. Ye, and Tatyana Voyno-Yasenetskaya

Cyclic AMP-independent Activation of Protein Kinase A by Vasoactive Peptides
J. Biol. Chem. 2001 276: 20827-20830. First Published on April 30, 2001; doi:10.1074/jbc.C100195200 [Abstract] [Full Text] [PDF]  

DNA: Replication, Repair, and Recombination:

Dina R. Marenstein, Maria T. A. Ocampo, Michael K. Chan, Alvin Altamirano, Ashis K. Basu, Robert J. Boorstein, Richard P. Cunningham, and George W. Teebor

Stimulation of Human Endonuclease III by Y Box-binding Protein 1 (DNA-binding Protein B). INTERACTION BETWEEN A BASE EXCISION REPAIR ENZYME AND A TRANSCRIPTION FACTOR
J. Biol. Chem. 2001 276: 21242-21249. First Published on April 3, 2001; doi:10.1074/jbc.M101594200 [Abstract] [Full Text] [PDF]  

Masato Kato, David N. Frick, Joonsoo Lee, Stanley Tabor, Charles C. Richardson, and Tom Ellenberger

A Complex of the Bacteriophage T7 Primase-Helicase and DNA Polymerase Directs Primer Utilization
J. Biol. Chem. 2001 276: 21809-21820. First Published on March 28, 2001; doi:10.1074/jbc.M101470200 [Abstract] [Full Text] [PDF]  

Elbieta Speina, Jaroslaw M. Ciesla, Jacek Wójcik, Monika Bajek, Jaroslaw T. Kusmierek, and Barbara Tudek

The Pyrimidine Ring-opened Derivative of 1,N⁶-Ethenoadenine Is Excised from DNA by the Escherichia coli Fpg and Nth Proteins
J. Biol. Chem. 2001 276: 21821-21827. First Published on March 20, 2001; doi:10.1074/jbc.M100998200 [Abstract] [Full Text] [PDF]  

Genes: Structure and Regulation:

Joanna Czuwara-Ladykowska, Fumiaki Shirasaki, Pascale Jackers, Dennis K. Watson, and Maria Trojanowska

Fli-1 Inhibits Collagen Type I Production in Dermal Fibroblasts via an Sp1-dependent Pathway
J. Biol. Chem. 2001 276: 20839-20848. First Published on March 16, 2001; doi:10.1074/jbc.M010133200 [Abstract] [Full Text] [PDF]  

Chuan Hua He, Pengfei Gong, Bin Hu, Daniel Stewart, Mary E. Choi, Augustine M. K. Choi, and Jawed Alam

Identification of Activating Transcription Factor 4 (ATF4) as an Nrf2-interacting Protein. IMPLICATION FOR HEME OXYGENASE-1 GENE REGULATION
J. Biol. Chem. 2001 276: 20858-20865. First Published on March 26, 2001; doi:10.1074/jbc.M101198200 [Abstract] [Full Text] [PDF]  

Claire Dartigalongue, Dominique Missiakas, and Satish Raina

Characterization of the Escherichia coli ^E Regulon
J. Biol. Chem. 2001 276: 20866-20875. First Published on March 23, 2001; doi:10.1074/jbc.M100464200 [Abstract] [Full Text] [PDF]  

Atsuko Masumi and Keiko Ozato

Coactivator p300 Acetylates the Interferon Regulatory Factor-2 in U937 Cells following Phorbol Ester Treatment
J. Biol. Chem. 2001 276: 20973-20980. First Published on April 13, 2001; doi:10.1074/jbc.M101707200 [Abstract] [Full Text] [PDF]  

Adali Pecci, Luciana Rocha Viegas, José Lino Barañao, and Miguel Beato

Promoter Choice Influences Alternative Splicing and Determines the Balance of Isoforms Expressed from the Mouse bcl-X Gene
J. Biol. Chem. 2001 276: 21062-21069. First Published on March 26, 2001; doi:10.1074/jbc.M008665200 [Abstract] [Full Text] [PDF]  

Knut Eichhorn and Stephen P. Jackson

A Role for TAF3B2 in the Repression of Human RNA Polymerase III Transcription in Nonproliferating Cells
J. Biol. Chem. 2001 276: 21158-21165. First Published on March 30, 2001; doi:10.1074/jbc.M102295200 [Abstract] [Full Text] [PDF]  

Mark H. Kaplan, Rui-Ting Zong, Richard F. Herrscher, Richard H. Scheuermann, and Philip W. Tucker

Transcriptional Activation by a Matrix Associating Region-binding Protein. CONTEXTUAL REQUIREMENTS FOR THE FUNCTION OF BRIGHT
J. Biol. Chem. 2001 276: 21325-21330. First Published on April 6, 2001; doi:10.1074/jbc.M100836200 [Abstract] [Full Text] [PDF]  

Julie Lovshin, Jennifer Estall, Bernardo Yusta, Theodore J. Brown, and Daniel J. Drucker

Glucagon-like Peptide (GLP)-2 Action in the Murine Central Nervous System Is Enhanced by Elimination of GLP-1 Receptor Signaling
J. Biol. Chem. 2001 276: 21489-21499. First Published on March 21, 2001; doi:10.1074/jbc.M009382200 [Abstract] [Full Text] [PDF]  

Eric L. Routhier, Timothy C. Burn, Ilgar Abbaszade, Matthew Summers, Charles F. Albright, and George C. Prendergast

Human BIN3 Complements the F-actin Localization Defects Caused by Loss of Hob3p, the Fission Yeast Homolog of Rvs161p
J. Biol. Chem. 2001 276: 21670-21677. First Published on March 23, 2001; doi:10.1074/jbc.M101096200 [Abstract] [Full Text] [PDF]  

Cong Yan, Angela Naltner, Julie Conkright, and Manely Ghaffari

Protein-Protein Interaction of Retinoic Acid Receptor and Thyroid Transcription Factor-1 in Respiratory Epithelial Cells
J. Biol. Chem. 2001 276: 21686-21691. First Published on March 23, 2001; doi:10.1074/jbc.M011378200 [Abstract] [Full Text] [PDF]  

Taras T. Antoniv, Sarah De Val, Dominic Wells, Christopher P. Denton, Christian Rabe, Benoit de Crombrugghe, Francesco Ramirez, and George Bou-Gharios

Characterization of an Evolutionarily Conserved Far-upstream Enhancer in the Human 2(I) Collagen (COL1A2) Gene
J. Biol. Chem. 2001 276: 21754-21764. First Published on March 28, 2001; doi:10.1074/jbc.M101397200 [Abstract] [Full Text] [PDF]  

Carl Costanzi and John R. Pehrson

MACROH2A2, a New Member of the MACROH2A Core Histone Family
J. Biol. Chem. 2001 276: 21776-21784. First Published on March 21, 2001; doi:10.1074/jbc.M010919200 [Abstract] [Full Text] [PDF]  

Vladimir R. Ramirez-Carrozzi and Tom K. Kerppola

Control of the Orientation of Fos-Jun Binding and the Transcriptional Cooperativity of Fos-Jun-NFAT1 Complexes
J. Biol. Chem. 2001 276: 21797-21808. First Published on March 19, 2001; doi:10.1074/jbc.M101494200 [Abstract] [Full Text] [PDF]  

Caterina Rufo, Margarita Teran-Garcia, Manabu T. Nakamura, Seung-Hoi Koo, Howard C. Towle, and Steven D. Clarke

Involvement of a Unique Carbohydrate-responsive Factor in the Glucose Regulation of Rat Liver Fatty-acid Synthase Gene Transcription
J. Biol. Chem. 2001 276: 21969-21975. First Published on March 28, 2001; doi:10.1074/jbc.M100461200 [Abstract] [Full Text] [PDF]  

RNA: Structure, Metabolism, and Catalysis:

Susanne Schneider and Beate Schwer

Functional Domains of the Yeast Splicing Factor Prp22p
J. Biol. Chem. 2001 276: 21184-21191. First Published on March 29, 2001; doi:10.1074/jbc.M101964200 [Abstract] [Full Text] [PDF]  

Aimin Tang and Norman P. Curthoys

Identification of -Crystallin/NADPH:Quinone Reductase as a Renal Glutaminase mRNA pH Response Element-binding Protein
J. Biol. Chem. 2001 276: 21375-21380. First Published on April 9, 2001; doi:10.1074/jbc.M101941200 [Abstract] [Full Text] [PDF]  

Phinikoula S. Katsamba, David G. Myszka, and Ite A. Laird-Offringa

Two Functionally Distinct Steps Mediate High Affinity Binding of U1A Protein to U1 Hairpin II RNA
J. Biol. Chem. 2001 276: 21476-21481. First Published on April 10, 2001; doi:10.1074/jbc.M101624200 [Abstract] [Full Text] [PDF]  

Karthika Perumal, Krishna Sinha, Dale Henning, and Ram Reddy

Purification, Characterization, and Cloning of the cDNA of Human Signal Recognition Particle RNA 3'-Adenylating Enzyme
J. Biol. Chem. 2001 276: 21791-21796. First Published on April 3, 2001; doi:10.1074/jbc.M101905200 [Abstract] [Full Text] [PDF]  

Protein Synthesis, Post-Translation Modification, and Degradation:

Vladimir I. Martynov, Alexander P. Savitsky, Natalya Y. Martynova, Pavel A. Savitsky, Konstantin A. Lukyanov, and Sergey A. Lukyanov

Alternative Cyclization in GFP-like Proteins Family. THE FORMATION AND STRUCTURE OF THE CHROMOPHORE OF A PURPLE CHROMOPROTEIN FROM ANEMONIA SULCATA
J. Biol. Chem. 2001 276: 21012-21016. First Published on March 19, 2001; doi:10.1074/jbc.M100500200 [Abstract] [Full Text] [PDF]  

Rolf Graf, Marc Schiesser, George A. Scheele, Klaus Marquardt, Thomas W. Frick, Rudolf W. Ammann, and Daniel Bimmler

A Family of 16-kDa Pancreatic Secretory Stress Proteins Form Highly Organized Fibrillar Structures upon Tryptic Activation
J. Biol. Chem. 2001 276: 21028-21038. First Published on March 16, 2001; doi:10.1074/jbc.M010717200 [Abstract] [Full Text] [PDF]  

Marwan Alfalah, Edward T. Parkin, Ralf Jacob, Edward D. Sturrock, Reinhard Mentele, Anthony J. Turner, Nigel M. Hooper, and Hassan Y. Naim

A Point Mutation in the Juxtamembrane Stalk of Human Angiotensin I-converting Enzyme Invokes the Action of a Distinct Secretase
J. Biol. Chem. 2001 276: 21105-21109. First Published on March 23, 2001; doi:10.1074/jbc.M100339200 [Abstract] [Full Text] [PDF]  

Manas K. Chattopadhyay, Yasuko Murakami, and Senya Matsufuji

Antizyme Regulates the Degradation of Ornithine Decarboxylase in Fission Yeast Schizosaccharomyces pombe. STUDY IN THE spe2 KNOCKOUT STRAINS
J. Biol. Chem. 2001 276: 21235-21241. First Published on March 30, 2001; doi:10.1074/jbc.M010643200 [Abstract] [Full Text] [PDF]  

Luis Ulloa, John W. M. Creemers, Samar Roy, Shaohua Liu, James Mason, and Siamak Tabibzadeh

Lefty Proteins Exhibit Unique Processing and Activate the MAPK Pathway
J. Biol. Chem. 2001 276: 21387-21396. First Published on February 20, 2001; doi:10.1074/jbc.M006933200 [Abstract] [Full Text] [PDF]  

Li-Mei Chen, Melanie L. Skinner, Steven W. Kauffman, Julie Chao, Lee Chao, Catherine D. Thaler, and Karl X. Chai

Prostasin Is a Glycosylphosphatidylinositol-anchored Active Serine Protease
J. Biol. Chem. 2001 276: 21434-21442. First Published on March 26, 2001; doi:10.1074/jbc.M011423200 [Abstract] [Full Text] [PDF]  

Takashi Ohtsuki, Yoh-ichi Watanabe, Chie Takemoto, Gota Kawai, Takuya Ueda, Kiyoshi Kita, Somei Kojima, Yoshito Kaziro, Jens Nyborg, and Kimitsuna Watanabe

An "Elongated" Translation Elongation Factor Tu for Truncated tRNAs in Nematode Mitochondria
J. Biol. Chem. 2001 276: 21571-21577. First Published on March 21, 2001; doi:10.1074/jbc.M011118200 [Abstract] [Full Text] [PDF]  

Tadashi Suzuki, Hangil Park, Michael A. Kwofie, and William J. Lennarz

Rad23 Provides a Link between the Png1 Deglycosylating Enzyme and the 26 S Proteasome in Yeast
J. Biol. Chem. 2001 276: 21601-21607. First Published on March 20, 2001; doi:10.1074/jbc.M100826200 [Abstract] [Full Text] [PDF]  

Ralf Kleene, Huibin Yang, Michael Kutsche, and Melitta Schachner

The Neural Recognition Molecule L1 Is a Sialic Acid-binding Lectin for CD24, Which Induces Promotion and Inhibition of Neurite Outgrowth
J. Biol. Chem. 2001 276: 21656-21663. First Published on March 30, 2001; doi:10.1074/jbc.M101790200 [Abstract] [Full Text] [PDF]  

Deborah A. Sampson, Min Wang, and Michael J. Matunis

The Small Ubiquitin-like Modifier-1 (SUMO-1) Consensus Sequence Mediates Ubc9 Binding and Is Essential for SUMO-1 Modification
J. Biol. Chem. 2001 276: 21664-21669. First Published on March 19, 2001; doi:10.1074/jbc.M100006200 [Abstract] [Full Text] [PDF]  

Tsutomu Suzuki, Maki Terasaki, Chie Takemoto-Hori, Takao Hanada, Takuya Ueda, Akira Wada, and Kimitsuna Watanabe

Structural Compensation for the Deficit of rRNA with Proteins in the Mammalian Mitochondrial Ribosome. SYSTEMATIC ANALYSIS OF PROTEIN COMPONENTS OF THE LARGE RIBOSOMAL SUBUNIT FROM MAMMALIAN MITOCHONDRIA
J. Biol. Chem. 2001 276: 21724-21736. First Published on February 21, 2001; doi:10.1074/jbc.M100432200 [Abstract] [Full Text] [PDF]  

Tiebang Kang, Jun Yi, Athena Guo, Xing Wang, Christopher M. Overall, Weiping Jiang, Robert Elde, Niels Borregaard, and Duanqing Pei

Subcellular Distribution and Cytokine- and Chemokine-regulated Secretion of Leukolysin/MT6-MMP/MMP-25 in Neutrophils
J. Biol. Chem. 2001 276: 21960-21968. First Published on March 29, 2001; doi:10.1074/jbc.M007997200 [Abstract] [Full Text] [PDF]  

Protein Structure and Folding:

Angelo Filosa and Ann M. English

Mass Spectral Analysis of Protein-based Radicals Using DBNBS. NONRADICAL ADDUCT FORMATION VERSUS SPIN TRAPPING
J. Biol. Chem. 2001 276: 21022-21027. First Published on March 21, 2001; doi:10.1074/jbc.M100644200 [Abstract] [Full Text] [PDF]  

Alicia Bravo, Gemma Serrano-Heras, and Margarita Salas

A Single Amino Acid Substitution within a Coiled-coil Motif Changes the Assembly of a 53-Amino Acid Protein from Two-dimensional Sheets to Filamentous Structures
J. Biol. Chem. 2001 276: 21250-21256. First Published on March 29, 2001; doi:10.1074/jbc.M011296200 [Abstract] [Full Text] [PDF]  

Frédéric Delom, Bernard Mallet, Pierre Carayon, and Pierre-Jean Lejeune

Role of Extracellular Molecular Chaperones in the Folding of Oxidized Proteins. REFOLDING OF COLLOIDAL THYROGLOBULIN BY PROTEIN DISULFIDE ISOMERASE AND IMMUNOGLOBULIN HEAVY CHAIN-BINDING PROTEIN
J. Biol. Chem. 2001 276: 21337-21342. First Published on April 9, 2001; doi:10.1074/jbc.M101086200 [Abstract] [Full Text] [PDF]  

Ashwani K. Sharma, Jennifer J. Kuhns, Shuqin Yan, Randall H. Friedline, Brian Long, Roland Tisch, and Edward J. Collins

Class I Major Histocompatibility Complex Anchor Substitutions Alter the Conformation of T Cell Receptor Contacts
J. Biol. Chem. 2001 276: 21443-21449. First Published on April 3, 2001; doi:10.1074/jbc.M010791200 [Abstract] [Full Text] [PDF]  

Vinod Subramaniam, Thomas M. Jovin, and Rolando V. Rivera-Pomar

Aromatic Amino Acids Are Critical for Stability of the Bicoid Homeodomain
J. Biol. Chem. 2001 276: 21506-21511. First Published on April 6, 2001; doi:10.1074/jbc.M102292200 [Abstract] [Full Text] [PDF]  

Giuseppe Orsomando, Maria Lorenzi, Nadia Raffaelli, Marco Dalla Rizza, Bruno Mezzetti, and Silverio Ruggieri

Phytotoxic Protein PcF, Purification, Characterization, and cDNA Sequencing of a Novel Hydroxyproline-containing Factor Secreted by the Strawberry Pathogen Phytophthora cactorum
J. Biol. Chem. 2001 276: 21578-21584. First Published on March 21, 2001; doi:10.1074/jbc.M101377200 [Abstract] [Full Text] [PDF]  

Sylvestre Grizot, Franck Fieschi, Marie-Claire Dagher, and Eva Pebay-Peyroula

The Active N-terminal Region of p67^phox. STRUCTURE AT 1.8 Å RESOLUTION AND BIOCHEMICAL CHARACTERIZATIONS OF THE A128V MUTANT IMPLICATED IN CHRONIC GRANULOMATOUS DISEASE
J. Biol. Chem. 2001 276: 21627-21631. First Published on March 21, 2001; doi:10.1074/jbc.M100893200 [Abstract] [Full Text] [PDF]  

Z. Hong Zhou, Wangcai Liao, R. Holland Cheng, J. E. Lawson, D. B. McCarthy, Lester J. Reed, and James K. Stoops

Direct Evidence for the Size and Conformational Variability of the Pyruvate Dehydrogenase Complex Revealed by Three-dimensional Electron Microscopy. THE "BREATHING" CORE AND ITS FUNCTIONAL RELATIONSHIP TO PROTEIN DYNAMICS
J. Biol. Chem. 2001 276: 21704-21713. First Published on April 2, 2001; doi:10.1074/jbc.M101765200 [Abstract] [Full Text] [PDF] Supplemental Data  

Per Hammarström, Malin Persson, and Uno Carlsson

Protein Compactness Measured by Fluorescence Resonance Energy Transfer. HUMAN CARBONIC ANHYDRASE II IS CONSIDERABLY EXPANDED BY THE INTERACTION OF GroEL
J. Biol. Chem. 2001 276: 21765-21775. First Published on February 26, 2001; doi:10.1074/jbc.M010858200 [Abstract] [Full Text] [PDF]  

Enzyme Catalysis and Regulation:

Bjorn Vergauwen, Frederik Pauwels, Françoise Jacquemotte, Terrance E. Meyer, Michael A. Cusanovich, Robert G. Bartsch, and Jozef J. Van Beeumen

Characterization of Glutathione Amide Reductase from Chromatium gracile. IDENTIFICATION OF A NOVEL THIOL PEROXIDASE (Prx/Grx) FUELED BY GLUTATHIONE AMIDE REDOX CYCLING
J. Biol. Chem. 2001 276: 20890-20897. First Published on April 3, 2001; doi:10.1074/jbc.M102026200 [Abstract] [Full Text] [PDF]  

Berit O. Krogh, Christopher D. Claeboe, Sidney M. Hecht, and Stewart Shuman

Effect of 2'-5' Phosphodiesters on DNA Transesterification by Vaccinia Topoisomerase
J. Biol. Chem. 2001 276: 20907-20912. First Published on April 3, 2001; doi:10.1074/jbc.M102312200 [Abstract] [Full Text] [PDF]  

Giedrius Vilkaitis, Egl Merkien, Saulius Serva, Elmar Weinhold, and Saulius Klimaauskas

The Mechanism of DNA Cytosine-5 Methylation. KINETIC AND MUTATIONAL DISSECTION OF HhaI METHYLTRANSFERASE
J. Biol. Chem. 2001 276: 20924-20934. First Published on March 29, 2001; doi:10.1074/jbc.M101429200 [Abstract] [Full Text] [PDF]  

Patricia C. Y. Liaw, Debra L. Becker, Alan R. Stafford, James C. Fredenburgh, and Jeffrey I. Weitz

Molecular Basis for the Susceptibility of Fibrin-bound Thrombin to Inactivation by Heparin Cofactor II in the Presence of Dermatan Sulfate but Not Heparin
J. Biol. Chem. 2001 276: 20959-20965. First Published on April 9, 2001; doi:10.1074/jbc.M010584200 [Abstract] [Full Text] [PDF]  

Vicki L. Knowles, Catherine S. Smith, Christopher R. Smith, and William C. Plaxton

Structural and Regulatory Properties of Pyruvate Kinase from the Cyanobacterium Synechococcus PCC 6301
J. Biol. Chem. 2001 276: 20966-20972. First Published on April 9, 2001; doi:10.1074/jbc.M008878200 [Abstract] [Full Text] [PDF]  

Peter Schotte, Reinout Schauvliege, Sophie Janssens, and Rudi Beyaert

The Cathepsin B Inhibitor z-FA.fmk Inhibits Cytokine Production in Macrophages Stimulated by Lipopolysaccharide
J. Biol. Chem. 2001 276: 21153-21157. First Published on April 4, 2001; doi:10.1074/jbc.M102239200 [Abstract] [Full Text] [PDF]  

Henri-Pierre Fierobe, Adva Mechaly, Chantal Tardif, Anne Belaich, Raphael Lamed, Yuval Shoham, Jean-Pierre Belaich, and Edward A. Bayer

Design and Production of Active Cellulosome Chimeras. SELECTIVE INCORPORATION OF DOCKERIN-CONTAINING ENZYMES INTO DEFINED FUNCTIONAL COMPLEXES
J. Biol. Chem. 2001 276: 21257-21261. First Published on April 4, 2001; doi:10.1074/jbc.M102082200 [Abstract] [Full Text] [PDF]  

Ruslan Aphasizhev and Larry Simpson

Isolation and Characterization of a U-specific 3'-5'-Exonuclease from Mitochondria of Leishmania tarentolae
J. Biol. Chem. 2001 276: 21280-21284. First Published on March 28, 2001; doi:10.1074/jbc.M100297200 [Abstract] [Full Text] [PDF]  

Takashi Yamaoka, Makiko Yano, Maki Kondo, Hidemi Sasaki, Satoshi Hino, Rumi Katashima, Maki Moritani, and Mitsuo Itakura

Feedback Inhibition of Amidophosphoribosyltransferase Regulates the Rate of Cell Growth via Purine Nucleotide, DNA, and Protein Syntheses
J. Biol. Chem. 2001 276: 21285-21291. First Published on April 4, 2001; doi:10.1074/jbc.M011103200 [Abstract] [Full Text] [PDF]  

Natalie D. King and Mark R. O'Brian

Evidence for Direct Interaction between Enzyme I^Ntr and Aspartokinase to Regulate Bacterial Oligopeptide Transport
J. Biol. Chem. 2001 276: 21311-21316. First Published on April 3, 2001; doi:10.1074/jbc.M101982200 [Abstract] [Full Text] [PDF]  

Elizabeth A. Walker, Anya M. Clark, M. Hewison, Jon P. Ride, and Paul M. Stewart

Functional Expression, Characterization, and Purification of the Catalytic Domain of Human 11--Hydroxysteroid Dehydrogenase Type 1
J. Biol. Chem. 2001 276: 21343-21350. First Published on April 6, 2001; doi:10.1074/jbc.M011142200 [Abstract] [Full Text] [PDF]  

Gaochao Tian and Curt D. Haffner

Linear Relationships between the Ligand Binding Energy and the Activation Energy of Time-dependent Inhibition of Steroid 5-Reductase by ¹-4-Azasteroids
J. Biol. Chem. 2001 276: 21359-21364. First Published on March 8, 2001; doi:10.1074/jbc.M100793200 [Abstract] [Full Text] [PDF]  

Olaf Kniemeyer and Johann Heider

Ethylbenzene Dehydrogenase, a Novel Hydrocarbon-oxidizing Molybdenum/Iron-Sulfur/Heme Enzyme
J. Biol. Chem. 2001 276: 21381-21386. First Published on April 9, 2001; doi:10.1074/jbc.M101679200 [Abstract] [Full Text] [PDF]  

Marialore Sulpizi, Pierre Schelling, Gerd Folkers, Paolo Carloni, and Leonardo Scapozza

The Rational of Catalytic Activity of Herpes Simplex Virus Thymidine Kinase. A COMBINED BIOCHEMICAL AND QUANTUM CHEMICAL STUDY
J. Biol. Chem. 2001 276: 21692-21697. First Published on March 21, 2001; doi:10.1074/jbc.M010223200 [Abstract] [Full Text] [PDF]  

Michael T. Overgaard, Henning B. Boldt, Lisbeth S. Laursen, Lars Sottrup-Jensen, Cheryl A. Conover, and Claus Oxvig

Pregnancy-associated Plasma Protein-A2 (PAPP-A2), a Novel Insulin-like Growth Factor-binding Protein-5 Proteinase
J. Biol. Chem. 2001 276: 21849-21853. First Published on March 22, 2001; doi:10.1074/jbc.M102191200 [Abstract] [Full Text] [PDF]  

Keiro Shirotani, Satoshi Tsubuki, Nobuhisa Iwata, Yoshie Takaki, Wakako Harigaya, Kei Maruyama, Sumiko Kiryu-Seo, Hiroshi Kiyama, Hiroshi Iwata, Taisuke Tomita, Takeshi Iwatsubo, and Takaomi C. Saido

Neprilysin Degrades Both Amyloid Peptides 1-40 and 1-42 Most Rapidly and Efficiently among Thiorphan- and Phosphoramidon-sensitive Endopeptidases
J. Biol. Chem. 2001 276: 21895-21901. First Published on March 6, 2001; doi:10.1074/jbc.M008511200 [Abstract] [Full Text] [PDF]  

Glycobiology and Extracellular Matrices:

Bernd Kneidinger, Michael Graninger, Michael Puchberger, Paul Kosma, and Paul Messner

Biosynthesis of Nucleotide-activated D-glycero-D-manno-Heptose
J. Biol. Chem. 2001 276: 20935-20944. First Published on March 28, 2001; doi:10.1074/jbc.M100378200 [Abstract] [Full Text] [PDF]  

Daniel Llull, Ernesto García, and Rubens López

Tts, a Processive -Glucosyltransferase of Streptococcus pneumoniae, Directs the Synthesis of the Branched Type 37 Capsular Polysaccharide in Pneumococcus and Other Gram-positive Species
J. Biol. Chem. 2001 276: 21053-21061. First Published on March 22, 2001; doi:10.1074/jbc.M010287200 [Abstract] [Full Text] [PDF]  

Gerald Soslau, Reiner Class, Doris A. Morgan, Carolyn Foster, Susan T. Lord, Patrizia Marchese, and Zaverio M. Ruggeri

Unique Pathway of Thrombin-induced Platelet Aggregation Mediated by Glycoprotein Ib
J. Biol. Chem. 2001 276: 21173-21183. First Published on March 30, 2001; doi:10.1074/jbc.M008249200 [Abstract] [Full Text] [PDF]  

Brett E. Crawford, Sara K. Olson, Jeffrey D. Esko, and Maria A. S. Pinhal

Cloning, Golgi Localization, and Enzyme Activity of the Full-length Heparin/Heparan Sulfate-Glucuronic Acid C5-epimerase
J. Biol. Chem. 2001 276: 21538-21543. First Published on March 12, 2001; doi:10.1074/jbc.M100880200 [Abstract] [Full Text] [PDF]  

Kazuhisa Aoki, Nobuhiro Ishida, and Masao Kawakita

Substrate Recognition by UDP-galactose and CMP-sialic Acid Transporters. DIFFERENT SETS OF TRANSMEMBRANE HELICES ARE UTILIZED FOR THE SPECIFIC RECOGNITION OF UDP-GALACTOSE AND CMP-SIALIC ACID
J. Biol. Chem. 2001 276: 21555-21561. First Published on March 9, 2001; doi:10.1074/jbc.M101462200 [Abstract] [Full Text] [PDF]  

Patrick Legaigneur, Christelle Breton, Assou El Battari, Jean-Claude Guillemot, Claudine Augé, Martine Malissard, Eric G. Berger, and Catherine Ronin

Exploring the Acceptor Substrate Recognition of the Human -Galactoside 2,6-Sialyltransferase
J. Biol. Chem. 2001 276: 21608-21617. First Published on February 20, 2001; doi:10.1074/jbc.M100860200 [Abstract] [Full Text] [PDF]  

Mei Chen, Douglas R. Keene, Fritz K. Costa, Samuel H. Tahk, and David T. Woodley

The Carboxyl Terminus of Type VII Collagen Mediates Antiparallel Dimer Formation and Constitutes a New Antigenic Epitope for Epidermolysis Bullosa Acquisita Autoantibodies
J. Biol. Chem. 2001 276: 21649-21655. First Published on March 27, 2001; doi:10.1074/jbc.M100180200 [Abstract] [Full Text] [PDF]  

John F. Cipollo, Robert B. Trimble, Jung Hee Chi, Qi Yan, and Neta Dean

The Yeast ALG11 Gene Specifies Addition of the Terminal 1,2-Man to the Man₅GlcNAc₂-PP-dolichol N-Glycosylation Intermediate Formed on the Cytosolic Side of the Endoplasmic Reticulum
J. Biol. Chem. 2001 276: 21828-21840. First Published on February 15, 2001; doi:10.1074/jbc.M010896200 [Abstract] [Full Text] [PDF] Supplemental Data  

Lipids and Lipoproteins:

Jin-Bo Yang, Zhi-Jun Duan, Wei Yao, Oneil Lee, Li Yang, Xin-Ying Yang, Xia Sun, Catherine C. Y. Chang, Ta-Yuan Chang, and Bo-Liang Li

Synergistic Transcriptional Activation of Human Acyl-coenzyme A: Cholesterol Acyltransterase-1 Gene by Interferon- and All-trans-Retinoic Acid THP-1 Cells
J. Biol. Chem. 2001 276: 20989-20998. First Published on February 28, 2001; doi:10.1074/jbc.M011488200 [Abstract] [Full Text] [PDF]  

Snehasikta Swarnakar, Jeanette Beers, Dudley K. Strickland, Salman Azhar, and David L. Williams

The Apolipoprotein E-dependent Low Density Lipoprotein Cholesteryl Ester Selective Uptake Pathway in Murine Adrenocortical Cells Involves Chondroitin Sulfate Proteoglycans and an ₂-Macroglobulin Receptor
J. Biol. Chem. 2001 276: 21121-21128. First Published on March 26, 2001; doi:10.1074/jbc.M101691200 [Abstract] [Full Text] [PDF]  

Dan C. McManus, Brian R. Scott, Vivian Franklin, Daniel L. Sparks, and Yves L. Marcel

Proteolytic Degradation and Impaired Secretion of an Apolipoprotein A-I Mutant Associated with Dominantly Inherited Hypoalphalipoproteinemia
J. Biol. Chem. 2001 276: 21292-21302. First Published on April 5, 2001; doi:10.1074/jbc.M100463200 [Abstract] [Full Text] [PDF]  

Edward Whittle and John Shanklin

Engineering ⁹-16:0-Acyl Carrier Protein (ACP) Desaturase Specificity Based on Combinatorial Saturation Mutagenesis and Logical Redesign of the Castor ⁹-18:0-ACP Desaturase
J. Biol. Chem. 2001 276: 21500-21505. First Published on April 9, 2001; doi:10.1074/jbc.M102129200 [Abstract] [Full Text] [PDF]  

Satoshi Akiba, Ryo Hatazawa, Kyoko Ono, Kazuyuki Kitatani, Misako Hayama, and Takashi Sato

Secretory Phospholipase A₂ Mediates Cooperative Prostaglandin Generation by Growth Factor and Cytokine Independently of Preceding Cytosolic Phospholipase A₂ Expression in Rat Gastric Epithelial Cells
J. Biol. Chem. 2001 276: 21854-21862. First Published on March 23, 2001; doi:10.1074/jbc.M010201200 [Abstract] [Full Text] [PDF]  

Membrane Transport, Structure, Function, and Biogenesis:

Claus Schneider, Keri A. Tallman, Ned A. Porter, and Alan R. Brash

Two Distinct Pathways of Formation of 4-Hydroxynonenal. MECHANISMS OF NONENZYMATIC TRANSFORMATION OF THE 9- AND 13-HYDROPEROXIDES OF LINOLEIC ACID TO 4-HYDROXYALKENALS
J. Biol. Chem. 2001 276: 20831-20838. First Published on March 19, 2001; doi:10.1074/jbc.M101821200 [Abstract] [Full Text] [PDF]  

Matthew J. Harris, Michihiko Kuwano, Malcolm Webb, and Philip G. Board

Identification of the Apical Membrane-targeting Signal of the Multidrug Resistance-associated Protein 2 (MRP2/cMOAT)
J. Biol. Chem. 2001 276: 20876-20881. First Published on March 27, 2001; doi:10.1074/jbc.M010566200 [Abstract] [Full Text] [PDF]  

Michael Cascio, Scott Shenkel, Robert L. Grodzicki, Fred J. Sigworth, and Robert O. Fox

Functional Reconstitution and Characterization of Recombinant Human ₁-Glycine Receptors
J. Biol. Chem. 2001 276: 20981-20988. First Published on January 5, 2001; doi:10.1074/jbc.M010968200 [Abstract] [Full Text] [PDF]  

Marco Caprini, Stefano Ferroni, Rosa Planells-Cases, Joaquín Rueda, Carmela Rapisarda, Antonio Ferrer-Montiel, and Mauricio Montal

Structural Compatibility between the Putative Voltage Sensor of Voltage-gated K⁺ Channels and the Prokaryotic KcsA Channel
J. Biol. Chem. 2001 276: 21070-21076. First Published on March 26, 2001; doi:10.1074/jbc.M100487200 [Abstract] [Full Text] [PDF]  

Jean da Silva Correia, Katrin Soldau, Urs Christen, Peter S. Tobias, and Richard J. Ulevitch

Lipopolysaccharide Is in Close Proximity to Each of the Proteins in Its Membrane Receptor Complex. TRANSFER FROM CD14 TO TLR4 AND MD-2
J. Biol. Chem. 2001 276: 21129-21135. First Published on March 26, 2001; doi:10.1074/jbc.M009164200 [Abstract] [Full Text] [PDF]  

Alessandro Prinetti, Vanna Chigorno, Simona Prioni, Nicoletta Loberto, Nadia Marano, Guido Tettamanti, and Sandro Sonnino

Changes in the Lipid Turnover, Composition, and Organization, as Sphingolipid-enriched Membrane Domains, in Rat Cerebellar Granule Cells Developing in Vitro
J. Biol. Chem. 2001 276: 21136-21145. First Published on March 22, 2001; doi:10.1074/jbc.M010666200 [Abstract] [Full Text] [PDF]  

Zuben E. Sauna, Melissa M. Smith, Marianna Müller, and Suresh V. Ambudkar

Functionally Similar Vanadate-induced 8-Azidoadenosine 5'-[-³²P]Diphosphate-trapped Transition State Intermediates of Human P-glycoprotein Are Generated in the Absence and Presence of ATP Hydrolysis
J. Biol. Chem. 2001 276: 21199-21208. First Published on April 3, 2001; doi:10.1074/jbc.M100886200 [Abstract] [Full Text] [PDF]  

Marc H. Levin, Peter M. Haggie, L. Vetrivel, and A. S. Verkman

Diffusion in the Endoplasmic Reticulum of an Aquaporin-2 Mutant Causing Human Nephrogenic Diabetes Insipidus
J. Biol. Chem. 2001 276: 21331-21336. First Published on April 10, 2001; doi:10.1074/jbc.M101901200 [Abstract] [Full Text] [PDF]  

Ferruccio Galbiati, Jeffrey A. Engelman, Daniela Volonte, Xiao Lan Zhang, Carlo Minetti, Maomi Li, Harry Hou, Jr., Burkhard Kneitz, Winfried Edelmann, and Michael P. Lisanti

Caveolin-3 Null Mice Show a Loss of Caveolae, Changes in the Microdomain Distribution of the Dystrophin-Glycoprotein Complex, and T-tubule Abnormalities
J. Biol. Chem. 2001 276: 21425-21433. First Published on March 19, 2001; doi:10.1074/jbc.M100828200 [Abstract] [Full Text] [PDF]  

Claudia Riedel, Orlie Levy, and Nancy Carrasco

Post-transcriptional Regulation of the Sodium/Iodide Symporter by Thyrotropin
J. Biol. Chem. 2001 276: 21458-21463. First Published on April 4, 2001; doi:10.1074/jbc.M100561200 [Abstract] [Full Text] [PDF]  

Gisela Beutner, Virendra K. Sharma, David R. Giovannucci, David I. Yule, and Shey-Shing Sheu

Identification of a Ryanodine Receptor in Rat Heart Mitochondria
J. Biol. Chem. 2001 276: 21482-21488. First Published on April 10, 2001; doi:10.1074/jbc.M101486200 [Abstract] [Full Text] [PDF]  

Janet R. Lamb, Vivian Fu, Elizabeth Wirtz, and James D. Bangs

Functional Analysis of the Trypanosomal AAA Protein TbVCP with trans-Dominant ATP Hydrolysis Mutants
J. Biol. Chem. 2001 276: 21512-21520. First Published on March 9, 2001; doi:10.1074/jbc.M100235200 [Abstract] [Full Text] [PDF]  

Steven J. DeMarco and Emanuel E. Strehler

Plasma Membrane Ca²⁺-ATPase Isoforms 2b and 4b Interact Promiscuously and Selectively with Members of the Membrane-associated Guanylate Kinase Family of PDZ (PSD95/Dlg/ZO-1) Domain-containing Proteins
J. Biol. Chem. 2001 276: 21594-21600. First Published on March 26, 2001; doi:10.1074/jbc.M101448200 [Abstract] [Full Text] [PDF]  

Xiaolei Zhu, Michele Hadhazy, Margaret E. Groh, Matthew T. Wheeler, Robert Wollmann, and Elizabeth M. McNally

Overexpression of -Sarcoglycan Induces Severe Muscular Dystrophy. IMPLICATIONS FOR THE REGULATION OF SARCOGLYCAN ASSEMBLY
J. Biol. Chem. 2001 276: 21785-21790. First Published on April 3, 2001; doi:10.1074/jbc.M101877200 [Abstract] [Full Text] [PDF]  

Mechanisms Of Signal Transduction:

Sophie Tartare-Deckert, Marie-Noëlle Monthouel, Céline Charvet, Isabelle Foucault, Emmanuel Van Obberghen, Alain Bernard, Amnon Altman, and Marcel Deckert

Vav2 Activates c-fos Serum Response Element and CD69 Expression but Negatively Regulates Nuclear Factor of Activated T Cells and Interleukin-2 Gene Activation in T Lymphocyte
J. Biol. Chem. 2001 276: 20849-20857. First Published on March 21, 2001; doi:10.1074/jbc.M010588200 [Abstract] [Full Text] [PDF]  

Alexei Navdaev, Jeannine M. Clemetson, János Polgár, Beate E. Kehrel, Martin Glauner, Edith Magnenat, Timothy N. C. Wells, and Kenneth J. Clemetson

Aggretin, a Heterodimeric C-type Lectin from Calloselasma rhodostoma (Malayan Pit Viper), Stimulates Platelets by Binding to ₂₁ Integrin and Glycoprotein Ib, Activating Syk and Phospholipase C2, but Does Not Involve the Glycoprotein VI/Fc Receptor Chain Collagen Receptor
J. Biol. Chem. 2001 276: 20882-20889. First Published on April 3, 2001; doi:10.1074/jbc.M101585200 [Abstract] [Full Text] [PDF]  

Philip W. Hammond, Julia Alpin, Cecil E. Rise, Martin Wright, and Brent L. Kreider

In Vitro Selection and Characterization of Bcl-X_L-binding Proteins from a Mix of Tissue-specific mRNA Display Libraries
J. Biol. Chem. 2001 276: 20898-20906. First Published on March 30, 2001; doi:10.1074/jbc.M011641200 [Abstract] [Full Text] [PDF]  

Yiguo Zhang, Ziming Dong, Masaaki Nomura, Shuping Zhong, Nanyue Chen, Ann M. Bode, and Zigang Dong

Signal Transduction Pathways Involved in Phosphorylation and Activation of p70^S6K Following Exposure to UVA Irradiation
J. Biol. Chem. 2001 276: 20913-20923. First Published on March 28, 2001; doi:10.1074/jbc.M009047200 [Abstract] [Full Text] [PDF]  

T. N. Doan, M. Showkat Ali, and K. E. Bernstein

Tyrosine Kinase Activation by the Angiotensin II Receptor in the Absence of Calcium Signaling
J. Biol. Chem. 2001 276: 20954-20958. First Published on April 23, 2001; doi:10.1074/jbc.C100199200 [Abstract] [Full Text] [PDF]  

Tieli Wang, Pinar Arifoglu, Ze'ev Ronai, and Kenneth D. Tew

Glutathione S-transferase P1-1 (GSTP1-1) Inhibits c-Jun N-terminal Kinase (JNK1) Signaling through Interaction with the C Terminus
J. Biol. Chem. 2001 276: 20999-21003. First Published on March 9, 2001; doi:10.1074/jbc.M101355200 [Abstract] [Full Text] [PDF]  

Cheh Peng Lim and Xinmin Cao

Regulation of Stat3 Activation by MEK Kinase 1
J. Biol. Chem. 2001 276: 21004-21011. First Published on March 16, 2001; doi:10.1074/jbc.M007592200 [Abstract] [Full Text] [PDF]  

Pawan Kumar, Shigeru Hosaka, and Alisa E. Koch

Soluble E-selectin Induces Monocyte Chemotaxis through Src Family Tyrosine Kinases
J. Biol. Chem. 2001 276: 21039-21045. First Published on March 27, 2001; doi:10.1074/jbc.M009099200 [Abstract] [Full Text] [PDF]  

Mauricio Di Fulvio, Thomas M. Lincoln, Peter K. Lauf, and Norma C. Adragna

Protein Kinase G Regulates Potassium Chloride Cotransporter-3 Expression in Primary Cultures of Rat Vascular Smooth Muscle Cells
J. Biol. Chem. 2001 276: 21046-21052. First Published on March 27, 2001; doi:10.1074/jbc.M100901200 [Abstract] [Full Text] [PDF]  

Martin Paukert, Ralph Osteroth, Hyun-Soon Geisler, Uwe Brändle, Elisabeth Glowatzki, J. Peter Ruppersberg, and Stefan Gründer

Inflammatory Mediators Potentiate ATP-gated Channels through the P2X₃ Subunit
J. Biol. Chem. 2001 276: 21077-21082. First Published on March 22, 2001; doi:10.1074/jbc.M101465200 [Abstract] [Full Text] [PDF]  

Tianyan Gao, Adolfo E. Cuadra, Hong Ma, Moritz Bünemann, Brian L. Gerhardstein, Tong Cheng, Robert Ten Eick, and M. Marlene Hosey

C-terminal Fragments of the _1C (Ca_V1.2) Subunit Associate with and Regulate L-type Calcium Channels Containing C-terminal-truncated _1C Subunits
J. Biol. Chem. 2001 276: 21089-21097. First Published on March 26, 2001; doi:10.1074/jbc.M008000200 [Abstract] [Full Text] [PDF]  

Pu Chen, Terry D. Lee, and Henry K. W. Fong

Interaction of 11-cis-Retinol Dehydrogenase with the Chromophore of Retinal G Protein-coupled Receptor Opsin
J. Biol. Chem. 2001 276: 21098-21104. First Published on March 27, 2001; doi:10.1074/jbc.M010441200 [Abstract] [Full Text] [PDF]  

Lorna M. Dickson, Melissa K. Lingohr, Jill McCuaig, Sigrun R. Hügl, Lynn Snow, Barbara B. Kahn, Martin G. Myers, Jr., and Christopher J. Rhodes

Differential Activation of Protein Kinase B and p70^S6K by Glucose and Insulin-like Growth Factor 1 in Pancreatic -Cells (INS-1)
J. Biol. Chem. 2001 276: 21110-21120. First Published on March 27, 2001; doi:10.1074/jbc.M101257200 [Abstract] [Full Text] [PDF]  

Chun-Chi Liang and Hong-Chen Chen

Sustained Activation of Extracellular Signal-regulated Kinase Stimulated by Hepatocyte Growth Factor Leads to Integrin ₂ Expression That Is Involved in Cell Scattering
J. Biol. Chem. 2001 276: 21146-21152. First Published on April 3, 2001; doi:10.1074/jbc.M010669200 [Abstract] [Full Text] [PDF]  

Kiichi Hirota and Gregg L. Semenza

Rac1 Activity Is Required for the Activation of Hypoxia-inducible Factor 1
J. Biol. Chem. 2001 276: 21166-21172. First Published on March 30, 2001; doi:10.1074/jbc.M100677200 [Abstract] [Full Text] [PDF]  

Djenann Saint-Dic, Samantha C. Chang, Gregory S. Taylor, Melissa M. Provot, and Theodora S. Ross

Regulation of the Src Homology 2-containing Inositol 5-Phosphatase SHIP1 in HIP1/PDGFR-transformed Cells
J. Biol. Chem. 2001 276: 21192-21198. First Published on April 3, 2001; doi:10.1074/jbc.M008336200 [Abstract] [Full Text] [PDF]  

Ivan Tan, Chong Han Ng, Louis Lim, and Thomas Leung

Phosphorylation of a Novel Myosin Binding Subunit of Protein Phosphatase 1 Reveals a Conserved Mechanism in the Regulation of Actin Cytoskeleton
J. Biol. Chem. 2001 276: 21209-21216. First Published on April 3, 2001; doi:10.1074/jbc.M102615200 [Abstract] [Full Text] [PDF]  

Yasunobu Ogura, Yusuke Yoshida, Naoto Yabe, and Kohji Hasunuma

A Point Mutation in Nucleoside Diphosphate Kinase Results in a Deficient Light Response for Perithecial Polarity in Neurospora crassa
J. Biol. Chem. 2001 276: 21228-21234. First Published on April 3, 2001; doi:10.1074/jbc.M011381200 [Abstract] [Full Text] [PDF]  

Jessica L. Wood and Andrew F. Russo

Autoregulation of Cell-specific MAP Kinase Control of the Tryptophan Hydroxylase Promoter
J. Biol. Chem. 2001 276: 21262-21271. First Published on March 30, 2001; doi:10.1074/jbc.M007520200 [Abstract] [Full Text] [PDF]  

Mark K. Abe, Kristopher T. Kahle, Matthew P. Saelzler, Kim Orth, Jack E. Dixon, and Marsha R. Rosner

ERK7 Is an Autoactivated Member of the MAPK Family
J. Biol. Chem. 2001 276: 21272-21279. First Published on April 3, 2001; doi:10.1074/jbc.M100026200 [Abstract] [Full Text] [PDF]  

Jisen Tang, Yakang Lin, Zongming Zhang, Svetlana Tikunova, Lutz Birnbaumer, and Michael Xi Zhu

Identification of Common Binding Sites for Calmodulin and Inositol 1,4,5-Trisphosphate Receptors on the Carboxyl Termini of Trp Channels
J. Biol. Chem. 2001 276: 21303-21310. First Published on April 4, 2001; doi:10.1074/jbc.M102316200 [Abstract] [Full Text] [PDF]  

Virginie Bottero, Franca Rossi, Michel Samson, Mireille Mari, Paul Hofman, and Jean-François Peyron

IB-, the NF-B Inhibitory Subunit, Interacts with ANT, the Mitochondrial ATP/ADP Translocator
J. Biol. Chem. 2001 276: 21317-21324. First Published on April 3, 2001; doi:10.1074/jbc.M005850200 [Abstract] [Full Text] [PDF]  

Zhengmin Huang, Su-Li Cheng, and Eduardo Slatopolsky

Sustained Activation of the Extracellular Signal-regulated Kinase Pathway Is Required for Extracellular Calcium Stimulation of Human Osteoblast Proliferation
J. Biol. Chem. 2001 276: 21351-21358. First Published on April 5, 2001; doi:10.1074/jbc.M010921200 [Abstract] [Full Text] [PDF]  

Olivier Mignen and Trevor J. Shuttleworth

Permeation of Monovalent Cations through the Non-capacitative Arachidonate-regulated Ca²⁺ Channels in HEK293 Cells. COMPARISON WITH ENDOGENOUS STORE-OPERATED CHANNELS
J. Biol. Chem. 2001 276: 21365-21374. First Published on April 2, 2001; doi:10.1074/jbc.M102311200 [Abstract] [Full Text] [PDF]  

Luis Ulloa and Siamak Tabibzadeh

Lefty Inhibits Receptor-regulated Smad Phosphorylation Induced by the Activated Transforming Growth Factor- Receptor
J. Biol. Chem. 2001 276: 21397-21404. First Published on February 20, 2001; doi:10.1074/jbc.M010783200 [Abstract] [Full Text] [PDF]  

Lin Wang, Yin Guo, Waan-Jeng Huang, Xiaoling Ke, Jean-Luc Poyet, Gulam A. Manji, Sarah Merriam, M. Alexandra Glucksmann, Peter S. DiStefano, Emad S. Alnemri, and John Bertin

CARD10 Is a Novel Caspase Recruitment Domain/Membrane-associated Guanylate Kinase Family Member That Interacts with BCL10 and Activates NF-B
J. Biol. Chem. 2001 276: 21405-21409. First Published on March 20, 2001; doi:10.1074/jbc.M102488200 [Abstract] [Full Text] [PDF]  

Weidong Li, Akira Okano, Qing Bao Tian, Kohzo Nakayama, Takashi Furihata, Hiroyuki Nawa, and Tatsuo Suzuki

Characterization of a Novel synGAP Isoform, synGAP-
J. Biol. Chem. 2001 276: 21417-21424. First Published on February 27, 2001; doi:10.1074/jbc.M010744200 [Abstract] [Full Text] [PDF]  

Christopher Silvin, Barbara Belisle, and Arie Abo

A Role for Wiskott-Aldrich Syndrome Protein in T-cell Receptor-mediated Transcriptional Activation Independent of Actin Polymerization
J. Biol. Chem. 2001 276: 21450-21457. First Published on March 30, 2001; doi:10.1074/jbc.M010729200 [Abstract] [Full Text] [PDF]  

Hichem C. Mertani, Tao Zhu, Eyleen L. K. Goh, Kok-Onn Lee, Gérard Morel, and Peter E. Lobie

Autocrine Human Growth Hormone (hGH) Regulation of Human Mammary Carcinoma Cell Gene Expression. IDENTIFICATION OF CHOP AS A MEDIATOR OF hGH-STIMULATED HUMAN MAMMARY CARCINOMA CELL SURVIVAL
J. Biol. Chem. 2001 276: 21464-21475. First Published on April 10, 2001; doi:10.1074/jbc.M100437200 [Abstract] [Full Text] [PDF]  

Andrey Sorokin, Piotr Kozlowski, Lee Graves, and Andrew Philip

Protein-tyrosine Kinase Pyk2 Mediates Endothelin-induced p38 MAPK Activation in Glomerular Mesangial Cells
J. Biol. Chem. 2001 276: 21521-21528. First Published on February 26, 2001; doi:10.1074/jbc.M008869200 [Abstract] [Full Text] [PDF]  

Luciano Pirola, Marketa J. Zvelebil, Genevieve Bulgarelli-Leva, Emmanuel Van Obberghen, Michael D. Waterfield, and Matthias P. Wymann

Activation Loop Sequences Confer Substrate Specificity to Phosphoinositide 3-Kinase (PI3K). FUNCTIONS OF LIPID KINASE-DEFICIENT PI3K IN SIGNALING
J. Biol. Chem. 2001 276: 21544-21554. First Published on February 13, 2001; doi:10.1074/jbc.M011330200 [Abstract] [Full Text] [PDF]  

Thierry Christophe, Anna Karlsson, Christophe Dugave, Marie-Josèphe Rabiet, Francois Boulay, and Claes Dahlgren

The Synthetic Peptide Trp-Lys-Tyr-Met-Val-Met-NH₂ Specifically Activates Neutrophils through FPRL1/Lipoxin A₄ Receptors and Is an Agonist for the Orphan Monocyte-expressed Chemoattractant Receptor FPRL2
J. Biol. Chem. 2001 276: 21585-21593. First Published on April 2, 2001; doi:10.1074/jbc.M007769200 [Abstract] [Full Text] [PDF]  

Dvorah Daily, Alexios Vlamis-Gardikas, Daniel Offen, Leonid Mittelman, Eldad Melamed, Arne Holmgren, and Ari Barzilai

Glutaredoxin Protects Cerebellar Granule Neurons from Dopamine-induced Apoptosis by Dual Activation of the Ras-Phosphoinositide 3-Kinase and Jun N-terminal Kinase Pathways
J. Biol. Chem. 2001 276: 21618-21626. First Published on April 4, 2001; doi:10.1074/jbc.M101400200 [Abstract] [Full Text] [PDF]  

Luisa Franco, Elena Zocchi, Cesare Usai, Lucrezia Guida, Santina Bruzzone, Aurora Costa, and Antonio De Flora

Paracrine Roles of NAD⁺ and Cyclic ADP-ribose in Increasing Intracellular Calcium and Enhancing Cell Proliferation of 3T3 Fibroblasts
J. Biol. Chem. 2001 276: 21642-21648. First Published on March 27, 2001; doi:10.1074/jbc.M010536200 [Abstract] [Full Text] [PDF]  

Alexey E. Granovsky and Nikolai O. Artemyev

Partial Reconstitution of Photoreceptor cGMP Phosphodiesterase Characteristics in cGMP Phosphodiesterase-5
J. Biol. Chem. 2001 276: 21698-21703. First Published on April 2, 2001; doi:10.1074/jbc.M100626200 [Abstract] [Full Text] [PDF]  

Luojing Chen, Khaleda Haider, Manish Ponda, Annaiah Cariappa, David Rowitch, and Shiv Pillai

Protein Kinase C-associated Kinase (PKK), a Novel Membrane-associated, Ankyrin Repeat-containing Protein Kinase
J. Biol. Chem. 2001 276: 21737-21744. First Published on February 6, 2001; doi:10.1074/jbc.M008069200 [Abstract] [Full Text] [PDF]  

Yan Wu, Donald Dowbenko, M. Teresa Pisabarro, Lisa Dillard-Telm, Hartmut Koeppen, and Laurence A. Lasky

PTEN 2, a Golgi-associated Testis-specific Homologue of the PTEN Tumor Suppressor Lipid Phosphatase
J. Biol. Chem. 2001 276: 21745-21753. First Published on March 2, 2001; doi:10.1074/jbc.M101480200 [Abstract] [Full Text] [PDF]  

Yoshihiko Miyata, Yoji Ikawa, Masabumi Shibuya, and Eisuke Nishida

Specific Association of a Set of Molecular Chaperones Including HSP90 and Cdc37 with MOK, a Member of the Mitogen-activated Protein Kinase Superfamily
J. Biol. Chem. 2001 276: 21841-21848. First Published on March 16, 2001; doi:10.1074/jbc.M010944200 [Abstract] [Full Text] [PDF]  

Sheue-Fang Shih, Yu-Hauh Wu, Chih-Hung Hung, Hui-Yu Yang, and Jung-Yaw Lin

Abrin Triggers Cell Death by Inactivating a Thiol-specific Antioxidant Protein
J. Biol. Chem. 2001 276: 21870-21877. First Published on April 2, 2001; doi:10.1074/jbc.M100571200 [Abstract] [Full Text] [PDF]  

Imanol Arozarena, David Matallanas, and Piero Crespo

Maintenance of Cdc42 GDP-bound State by Rho-GDI Inhibits MAP Kinase Activation by the Exchange Factor Ras-GRF. EVIDENCE FOR Ras-GRF FUNCTION BEING INHIBITED BY Cdc42-GDP BUT UNAFFECTED BY Cdc42-GTP
J. Biol. Chem. 2001 276: 21878-21884. First Published on April 2, 2001; doi:10.1074/jbc.M011383200 [Abstract] [Full Text] [PDF]  

Mathieu Houde, Patrick Laprise, Dominique Jean, Mylène Blais, Claude Asselin, and Nathalie Rivard

Intestinal Epithelial Cell Differentiation Involves Activation of p38 Mitogen-activated Protein Kinase That Regulates the Homeobox Transcription Factor CDX2
J. Biol. Chem. 2001 276: 21885-21894. First Published on March 30, 2001; doi:10.1074/jbc.M100236200 [Abstract] [Full Text] [PDF]  

Petra Rocic and Pamela A. Lucchesi

Down-regulation by Antisense Oligonucleotides Establishes a Role for the Proline-rich Tyrosine Kinase PYK2 in Angiotensin II-induced Signaling in Vascular Smooth Muscle
J. Biol. Chem. 2001 276: 21902-21906. First Published on March 21, 2001; doi:10.1074/jbc.M101684200 [Abstract] [Full Text] [PDF]  

Gabriela Paroni, Clare Henderson, Claudio Schneider, and Claudio Brancolini

Caspase-2-induced Apoptosis Is Dependent on Caspase-9, but Its Processing during UV- or Tumor Necrosis Factor-dependent Cell Death Requires Caspase-3
J. Biol. Chem. 2001 276: 21907-21915. First Published on March 16, 2001; doi:10.1074/jbc.M011565200 [Abstract] [Full Text] [PDF]  

Qi Tao, Marina V. Backer, Joseph M. Backer, and Bruce I. Terman

Kinase Insert Domain Receptor (KDR) Extracellular Immunoglobulin-like Domains 4-7 Contain Structural Features That Block Receptor Dimerization and Vascular Endothelial Growth Factor-induced Signaling
J. Biol. Chem. 2001 276: 21916-21923. First Published on March 16, 2001; doi:10.1074/jbc.M100763200 [Abstract] [Full Text] [PDF]  

Kalyankar Mahadev, Assaf Zilbering, Li Zhu, and Barry J. Goldstein

Insulin-stimulated Hydrogen Peroxide Reversibly Inhibits Protein-tyrosine Phosphatase 1B in Vivo and Enhances the Early Insulin Action Cascade
J. Biol. Chem. 2001 276: 21938-21942. First Published on April 10, 2001; doi:10.1074/jbc.C100109200 [Abstract] [Full Text] [PDF]  

Tatiana M. Grzeszkiewicz, Deborah J. Kirschling, Ningyu Chen, and Lester F. Lau

CYR61 Stimulates Human Skin Fibroblast Migration through Integrin _v5 and Enhances Mitogenesis through Integrin _v3, Independent of Its Carboxyl-terminal Domain
J. Biol. Chem. 2001 276: 21943-21950. First Published on April 3, 2001; doi:10.1074/jbc.M100978200 [Abstract] [Full Text] [PDF]  

Rodney E. Shackelford, Cynthia L. Innes, Stella O. Sieber, Alexandra N. Heinloth, Steven A. Leadon, and Richard S. Paules

The Ataxia telangiectasia Gene Product Is Required for Oxidative Stress-induced G₁ and G₂ Checkpoint Function in Human Fibroblasts
J. Biol. Chem. 2001 276: 21951-21959. First Published on April 4, 2001; doi:10.1074/jbc.M011303200 [Abstract] [Full Text] [PDF]  

Subhra Mohapatra, Deepak Agrawal, and W. J. Pledger

p27^Kip1 Regulates T Cell Proliferation
J. Biol. Chem. 2001 276: 21976-21983. First Published on April 10, 2001; doi:10.1074/jbc.M009788200 [Abstract] [Full Text] [PDF]  

Subhra Mohapatra and W. J. Pledger

Interdependence of cdk2 Activation and Interleukin-2R Accumulation in T Cells
J. Biol. Chem. 2001 276: 21984-21989. First Published on March 27, 2001; doi:10.1074/jbc.M100037200 [Abstract] [Full Text] [PDF]  

Molecular Basis Of Cell and Developmental Biology:

Shingo Nakahata, Yoshinao Katsu, Koichi Mita, Kunio Inoue, Yoshitaka Nagahama, and Masakane Yamashita

Biochemical Identification of Xenopus Pumilio as a Sequence-specific Cyclin B1 mRNA-binding Protein That Physically Interacts with a Nanos Homolog, Xcat-2, and a Cytoplasmic Polyadenylation Element-binding Protein
J. Biol. Chem. 2001 276: 20945-20953. First Published on March 29, 2001; doi:10.1074/jbc.M010528200 [Abstract] [Full Text] [PDF]  

Lauri D. Aicher, Jean S. Campbell, and Raymond S. Yeung

Tuberin Phosphorylation Regulates Its Interaction with Hamartin. TWO PROTEINS INVOLVED IN TUBEROUS SCLEROSIS
J. Biol. Chem. 2001 276: 21017-21021. First Published on April 4, 2001; doi:10.1074/jbc.C100136200 [Abstract] [Full Text] [PDF]  

Brent Berwin, Robyn C. Reed, and Christopher V. Nicchitta

Virally Induced Lytic Cell Death Elicits the Release of Immunogenic GRP94/gp96
J. Biol. Chem. 2001 276: 21083-21088. First Published on March 28, 2001; doi:10.1074/jbc.M101836200 [Abstract] [Full Text] [PDF]  

Véronique Martel, Claire Racaud-Sultan, Sandra Dupe, Christiane Marie, Frédérique Paulhe, Antoine Galmiche, Marc R. Block, and Corinne Albiges-Rizo

Conformation, Localization, and Integrin Binding of Talin Depend on Its Interaction with Phosphoinositides
J. Biol. Chem. 2001 276: 21217-21227. First Published on March 28, 2001; doi:10.1074/jbc.M102373200 [Abstract] [Full Text] [PDF]  

Morten Elholm, Inge Dam, Claus Jørgensen, Anne-M. Krogsdam, Dorte Holst, Irina Kratchmarova, Martin Göttlicher, Jan-Åke Gustafsson, Rolf Berge, Torgeir Flatmark, Jens Knudsen, Susanne Mandrup, and Karsten Kristiansen

Acyl-CoA Esters Antagonize the Effects of Ligands on Peroxisome Proliferator-activated Receptor Conformation, DNA Binding, and Interaction with Co-factors
J. Biol. Chem. 2001 276: 21410-21416. First Published on February 20, 2001; doi:10.1074/jbc.M101073200 [Abstract] [Full Text] [PDF]  

Yukari Tokuyama, Henning F. Horn, Kenji Kawamura, Pheruza Tarapore, and Kenji Fukasawa

Specific Phosphorylation of Nucleophosmin on Thr¹⁹⁹ by Cyclin- dependent Kinase 2-Cyclin E and Its Role in Centrosome Duplication
J. Biol. Chem. 2001 276: 21529-21537. First Published on February 27, 2001; doi:10.1074/jbc.M100014200 [Abstract] [Full Text] [PDF]  

M. Azhar Chishti, Dun-Shen Yang, Christopher Janus, Amie L. Phinney, Patrick Horne, Jacqueline Pearson, Robert Strome, Noah Zuker, James Loukides, Janet French, Sherry Turner, Gianluca Lozza, Mariagrazia Grilli, Suzanne Kunicki, Céline Morissette, Julie Paquette, Francine Gervais, Catherine Bergeron, Paul E. Fraser, George A. Carlson, Peter St. George-Hyslop, and David Westaway

Early-onset Amyloid Deposition and Cognitive Deficits in Transgenic Mice Expressing a Double Mutant Form of Amyloid Precursor Protein 695
J. Biol. Chem. 2001 276: 21562-21570. First Published on March 15, 2001; doi:10.1074/jbc.M100710200 [Abstract] [Full Text] [PDF]  

Jeffrey K. Harrison, Alan M. Fong, Peter A. W. Swain, Shuzhen Chen, Yen-Rei A. Yu, Mina N. Salafranca, William B. Greenleaf, Toshio Imai, and Dhavalkumar D. Patel

Mutational Analysis of the Fractalkine Chemokine Domain. BASIC AMINO ACID RESIDUES DIFFERENTIALLY CONTRIBUTE TO CX3CR1 BINDING, SIGNALING, AND CELL ADHESION
J. Biol. Chem. 2001 276: 21632-21641. First Published on March 8, 2001; doi:10.1074/jbc.M010261200 [Abstract] [Full Text] [PDF]  

Hiroshi Iwata, Taisuke Tomita, Kei Maruyama, and Takeshi Iwatsubo

Subcellular Compartment and Molecular Subdomain of -Amyloid Precursor Protein Relevant to the A42-promoting Effects of Alzheimer Mutant Presenilin 2
J. Biol. Chem. 2001 276: 21678-21685. First Published on March 30, 2001; doi:10.1074/jbc.M007989200 [Abstract] [Full Text] [PDF]  

Zhiyi Cao, Zheng Zhao, Royce Mohan, Joseph Alroy, Pamela Stanley, and Noorjahan Panjwani

Role of the Lewis^x Glycan Determinant in Corneal Epithelial Cell Adhesion and Differentiation
J. Biol. Chem. 2001 276: 21714-21723. First Published on March 15, 2001; doi:10.1074/jbc.M009672200 [Abstract] [Full Text] [PDF]  

Takeshi Isoyama, Asako Murayama, Akio Nomoto, and Shusuke Kuge

Nuclear Import of the Yeast AP-1-like Transcription Factor Yap1p Is Mediated by Transport Receptor Pse1p, and This Import Step Is Not Affected by Oxidative Stress
J. Biol. Chem. 2001 276: 21863-21869. First Published on March 23, 2001; doi:10.1074/jbc.M009258200 [Abstract] [Full Text] [PDF]  

Edwin E. Traverso, Christopher Baskerville, Yan Liu, Wenying Shou, Philip James, Raymond J. Deshaies, and Harry Charbonneau

Characterization of the Net1 Cell Cycle-dependent Regulator of the Cdc14 Phosphatase from Budding Yeast
J. Biol. Chem. 2001 276: 21924-21931. First Published on March 27, 2001; doi:10.1074/jbc.M011689200 [Abstract] [Full Text] [PDF]  

Alison Skeel and Edward J. Leonard

₁-Antichymotrypsin Is the Human Plasma Inhibitor of Macrophage Ectoenzymes That Cleave Pro-macrophage Stimulating Protein
J. Biol. Chem. 2001 276: 21932-21937. First Published on March 23, 2001; doi:10.1074/jbc.M100652200 [Abstract] [Full Text] [PDF]  

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