Minireviews:

Timothy J. Griffin and Ruedi Aebersold

Advances in Proteome Analysis by Mass Spectrometry
J. Biol. Chem. 2001 276: 45497-45500. First Published on October 3, 2001; 10.1074/jbc.R100014200 [Full Text] [PDF]  

Accelerated Publications:

Susan Mackem, Christopher T. Baumann, and Gordon L. Hager

A Glucocorticoid/Retinoic Acid Receptor Chimera That Displays Cytoplasmic/Nuclear Translocation in Response to Retinoic Acid. A REAL TIME SENSING ASSAY FOR NUCLEAR RECEPTOR LIGANDS
J. Biol. Chem. 2001 276: 45501-45504. First Published on October 3, 2001; 10.1074/jbc.C100269200 [Abstract] [Full Text] [PDF]  

Mark J. Schofield, Floyd E. Brownewell, Sunil Nayak, Chunwei Du, Eric T. Kool, and Peggy Hsieh

The Phe-X-Glu DNA Binding Motif of MutS. THE ROLE OF HYDROGEN BONDING IN MISMATCH RECOGNITION
J. Biol. Chem. 2001 276: 45505-45508. First Published on October 15, 2001; 10.1074/jbc.C100449200 [Abstract] [Full Text] [PDF]  

Adriano Marchese and Jeffrey L. Benovic

Agonist-promoted Ubiquitination of the G Protein-coupled Receptor CXCR4 Mediates Lysosomal Sorting
J. Biol. Chem. 2001 276: 45509-45512. First Published on October 18, 2001; 10.1074/jbc.C100527200 [Abstract] [Full Text] [PDF]  

Julia Tandori, Laura Baciou, Emil Alexov, Péter Maróti, Marianne Schiffer, Deborah K. Hanson, and Pierre Sebban

Revealing the Involvement of Extended Hydrogen Bond Networks in the Cooperative Function between Distant Sites in Bacterial Reaction Centers
J. Biol. Chem. 2001 276: 45513-45515. First Published on October 16, 2001; 10.1074/jbc.C100537200 [Abstract] [Full Text] [PDF]  

DNA: Replication Repair and Recombination:

Julie M. Bork, Michael M. Cox, and Ross B. Inman

RecA Protein Filaments Disassemble in the 5' to 3' Direction on Single-stranded DNA
J. Biol. Chem. 2001 276: 45740-45743. First Published on September 26, 2001; 10.1074/jbc.M109247200 [Abstract] [Full Text] [PDF]  

Jingsheng Tuo, Meltem Müftüoglu, Catheryne Chen, Pawel Jaruga, Rebecca R. Selzer, Robert M. Brosh, Jr., Henry Rodriguez, Miral Dizdaroglu, and Vilhelm A. Bohr

The Cockayne Syndrome Group B Gene Product Is Involved in General Genome Base Excision Repair of 8-Hydroxyguanine in DNA
J. Biol. Chem. 2001 276: 45772-45779. First Published on October 1, 2001; 10.1074/jbc.M107888200 [Abstract] [Full Text] [PDF]  

Stéphanie Marsin, Stephen McGovern, S. Dusko Ehrlich, Claude Bruand, and Patrice Polard

Early Steps of Bacillus subtilis Primosome Assembly
J. Biol. Chem. 2001 276: 45818-45825. First Published on October 3, 2001; 10.1074/jbc.M101996200 [Abstract] [Full Text] [PDF]  

Rupa Shree Appa, Cha-Gyun Shin, Philip Lee, and Samson A. Chow

Role of the Nonspecific DNA-binding Region and Helices within the Core Domain of Retroviral Integrase in Selecting Target DNA Sites for Integration
J. Biol. Chem. 2001 276: 45848-45855. First Published on October 3, 2001; 10.1074/jbc.M107365200 [Abstract] [Full Text] [PDF]  

Mothe Sreedhar Reddy, N. Guhan, and K. Muniyappa

Characterization of Single-stranded DNA-binding Proteins from Mycobacteria. THE CARBOXYL-TERMINAL DOMAIN OF SSB IS ESSENTIAL FOR STABLE ASSOCIATION WITH ITS COGNATE RecA PROTEIN
J. Biol. Chem. 2001 276: 45959-45968. First Published on September 27, 2001; 10.1074/jbc.M103523200 [Abstract] [Full Text] [PDF]  

Hoshing Wan Chang and Douglas A. Julin

Structure and Function of the Escherichia coli RecE Protein, a Member of the RecB Nuclease Domain Family
J. Biol. Chem. 2001 276: 46004-46010. First Published on October 4, 2001; 10.1074/jbc.M108627200 [Abstract] [Full Text] [PDF]  

Jaya K. Kumar, Robin Kremsdorf, Stanley Tabor, and Charles C. Richardson

A Mutation in the Gene-encoding Bacteriophage T7 DNA Polymerase That Renders the Phage Temperature-sensitive
J. Biol. Chem. 2001 276: 46151-46159. First Published on September 10, 2001; 10.1074/jbc.M106319200 [Abstract] [Full Text] [PDF]  

Karin Drotschmann, Wei Yang, Floyd E. Brownewell, Eric T. Kool, and Thomas A. Kunkel

Asymmetric Recognition of DNA Local Distortion. STRUCTURE-BASED FUNCTIONAL STUDIES OF EUKARYOTIC Msh2-Msh6
J. Biol. Chem. 2001 276: 46225-46229. First Published on October 18, 2001; 10.1074/jbc.C100450200 [Abstract] [Full Text] [PDF]  

Amy M. Wilstermann and Neil Osheroff

Base Excision Repair Intermediates as Topoisomerase II Poisons
J. Biol. Chem. 2001 276: 46290-46296. First Published on October 8, 2001; 10.1074/jbc.M105733200 [Abstract] [Full Text] [PDF]  

Dimitry Bosoy and Neal F. Lue

Functional Analysis of Conserved Residues in the Putative "Finger" Domain of Telomerase Reverse Transcriptase
J. Biol. Chem. 2001 276: 46305-46312. First Published on October 1, 2001; 10.1074/jbc.M108168200 [Abstract] [Full Text] [PDF]  

Thierry Viard, Valerie Lamour, Michel Duguet, and Claire Bouthier de la Tour

Hyperthermophilic Topoisomerase I from Thermotoga maritima. A VERY EFFICIENT ENZYME THAT FUNCTIONS INDEPENDENTLY OF ZINC BINDING
J. Biol. Chem. 2001 276: 46495-46503. First Published on September 27, 2001; 10.1074/jbc.M107714200 [Abstract] [Full Text] [PDF]  

Genes: Structure and Regulation:

Li Pan, Thomas A. Black, Qi Shi, Craig A. Jones, Nenad Petrovic, John Loudon, Colleen Kane, Curt D. Sigmund, and Kenneth W. Gross

Critical Roles of a Cyclic AMP Responsive Element and an E-box in Regulation of Mouse Renin Gene Expression
J. Biol. Chem. 2001 276: 45530-45538. First Published on September 19, 2001; 10.1074/jbc.M103010200 [Abstract] [Full Text] [PDF]  

Tong Zhang, Michael W. Wolfe, and Mark S. Roberson

An Early Growth Response Protein (Egr) 1 cis-Element Is Required for Gonadotropin-releasing Hormone-induced Mitogen-activated Protein Kinase Phosphatase 2 Gene Expression
J. Biol. Chem. 2001 276: 45604-45613. First Published on October 8, 2001; 10.1074/jbc.M107075200 [Abstract] [Full Text] [PDF]  

Claudia M. Litterst and Edith Pfitzner

Transcriptional Activation by STAT6 Requires the Direct Interaction with NCoA-1
J. Biol. Chem. 2001 276: 45713-45721. First Published on September 26, 2001; 10.1074/jbc.M108132200 [Abstract] [Full Text] [PDF]  

Thomas Mikita, Gordon Porter, Richard M. Lawn, and Dov Shiffman

Oxidized Low Density Lipoprotein Exposure Alters the Transcriptional Response of Macrophages to Inflammatory Stimulus
J. Biol. Chem. 2001 276: 45729-45739. First Published on September 27, 2001; 10.1074/jbc.M106114200 [Abstract] [Full Text] [PDF]  

Laura J. Moore and Patricia J. Kiley

Characterization of the Dimerization Domain in the FNR Transcription Factor
J. Biol. Chem. 2001 276: 45744-45750. First Published on October 1, 2001; 10.1074/jbc.M106569200 [Abstract] [Full Text] [PDF]  

Sang H. Jho, Nadezda Radoja, Mark J. Im, and Marjana Tomic-Canic

Negative Response Elements in Keratin Genes Mediate Transcriptional Repression and the Cross-talk among Nuclear Receptors
J. Biol. Chem. 2001 276: 45914-45920. First Published on October 8, 2001; 10.1074/jbc.M103144200 [Abstract] [Full Text] [PDF]  

Hidehiko Kawai, Linghu Nie, Dmitri Wiederschain, and Zhi-Min Yuan

Dual Role of p300 in the Regulation of p53 Stability
J. Biol. Chem. 2001 276: 45928-45932. First Published on October 8, 2001; 10.1074/jbc.M107770200 [Abstract] [Full Text] [PDF]  

Anette Wärnmark, Anja Wikström, Anthony P. H. Wright, Jan-Åke Gustafsson, and Torleif Härd

The N-terminal Regions of Estrogen Receptor and Are Unstructured in Vitro and Show Different TBP Binding Properties
J. Biol. Chem. 2001 276: 45939-45944. First Published on October 10, 2001; 10.1074/jbc.M107875200 [Abstract] [Full Text] [PDF]  

Hiroshi Katayama, Hongyi Zhou, Qun Li, Masaaki Tatsuka, and Subrata Sen

Interaction and Feedback Regulation between STK15/BTAK/Aurora-A Kinase and Protein Phosphatase 1 through Mitotic Cell Division Cycle
J. Biol. Chem. 2001 276: 46219-46224. First Published on September 10, 2001; 10.1074/jbc.M107540200 [Abstract] [Full Text] [PDF]  

Mineko Terao, Mami Kurosaki, Massimiliano Marini, Maria Antonietta Vanoni, Giuliana Saltini, Valentina Bonetto, Antonio Bastone, Concetta Federico, Salvatore Saccone, Roberto Fanelli, Mario Salmona, and Enrico Garattini

Purification of the Aldehyde Oxidase Homolog 1 (AOH1) Protein and Cloning of the AOH1 and Aldehyde Oxidase Homolog 2 (AOH2) Genes. IDENTIFICATION OF A NOVEL MOLYBDO-FLAVOPROTEIN GENE CLUSTER ON MOUSE CHROMOSOME 1
J. Biol. Chem. 2001 276: 46347-46363. First Published on September 18, 2001; 10.1074/jbc.M105744200 [Abstract] [Full Text] [PDF]  

Takenori Miyao, John D. Barnett, and Nancy A. Woychik

Deletion of the RNA Polymerase Subunit RPB4 Acts as a Global, Not Stress-specific, Shut-off Switch for RNA Polymerase II Transcription at High Temperatures
J. Biol. Chem. 2001 276: 46408-46413. First Published on September 27, 2001; 10.1074/jbc.M107012200 [Abstract] [Full Text] [PDF]  

Akiko Satou, Takahiro Taira, Sanae M. M. Iguchi-Ariga, and Hiroyoshi Ariga

A Novel Transrepression Pathway of c-Myc. RECRUITMENT OF A TRANSCRIPTIONAL COREPRESSOR COMPLEX TO c-Myc BY MM-1, A c-Myc-BINDING PROTEIN
J. Biol. Chem. 2001 276: 46562-46567. First Published on October 3, 2001; 10.1074/jbc.M104937200 [Abstract] [Full Text] [PDF]  

Xin Yuan, Michael L. Lu, Tong Li, and Steven P. Balk

SRY Interacts with and Negatively Regulates Androgen Receptor Transcriptional Activity
J. Biol. Chem. 2001 276: 46647-46654. First Published on October 3, 2001; 10.1074/jbc.M108404200 [Abstract] [Full Text] [PDF]  

Ralph K. Lindemann, Pia Ballschmieter, Alfred Nordheim, and Jürgen Dittmer

Transforming Growth Factor Regulates Parathyroid Hormone-related Protein Expression in MDA-MB-231 Breast Cancer Cells through a Novel Smad/Ets Synergism
J. Biol. Chem. 2001 276: 46661-46670. First Published on October 4, 2001; 10.1074/jbc.M105816200 [Abstract] [Full Text] [PDF]  

RNA: Structure Metabolism and Catalysis:

Nina S. Entelis, Olga A. Kolesnikova, Semih Dogan, Robert P. Martin, and Ivan A. Tarassov

5 S rRNA and tRNA Import into Human Mitochondria. COMPARISON OF IN VITRO REQUIREMENTS
J. Biol. Chem. 2001 276: 45642-45653. First Published on September 10, 2001; 10.1074/jbc.M103906200 [Abstract] [Full Text] [PDF]  

Helge Großhans, Francois Lecointe, Henri Grosjean, Ed Hurt, and George Simos

Pus1p-dependent tRNA Pseudouridinylation Becomes Essential When tRNA Biogenesis Is Compromised in Yeast
J. Biol. Chem. 2001 276: 46333-46339. First Published on September 24, 2001; 10.1074/jbc.M107141200 [Abstract] [Full Text] [PDF]  

Paul P. Lau, Heidee Villanueva, Kunihisa Kobayashi, Makoto Nakamuta, Benny H.-J. Chang, and Lawrence Chan

A DnaJ Protein, Apobec-1-binding Protein-2, Modulates Apolipoprotein B mRNA Editing
J. Biol. Chem. 2001 276: 46445-46452. First Published on October 2, 2001; 10.1074/jbc.M109215200 [Abstract] [Full Text] [PDF]  

Apurba Kumar Sau, Gena DeVue Tribble, Ian Grainge, Rikke From Frøhlich, Birgitta Ruth Knudsen, and Makkuni Jayaram

Biochemical and Kinetic Analysis of the RNase Active Sites of the Integrase/Tyrosine Family Site-specific DNA Recombinases
J. Biol. Chem. 2001 276: 46612-46623. First Published on October 3, 2001; 10.1074/jbc.M106492200 [Abstract] [Full Text] [PDF]  

Protein Synthesis Post-Translation Modification and Degradation:

Yusuke Mimura, Peter Sondermann, Rodolfo Ghirlando, John Lund, Stephen P. Young, Margaret Goodall, and Roy Jefferis

Role of Oligosaccharide Residues of IgG1-Fc in FcRIIb Binding
J. Biol. Chem. 2001 276: 45539-45547. First Published on September 20, 2001; 10.1074/jbc.M107478200 [Abstract] [Full Text] [PDF]  

Anne-Laure Bulteau, Philippe Verbeke, Isabelle Petropoulos, Alain-François Chaffotte, and Bertrand Friguet

Proteasome Inhibition in Glyoxal-treated Fibroblasts and Resistance of Glycated Glucose-6-phosphate Dehydrogenase to 20 S Proteasome Degradation in Vitro
J. Biol. Chem. 2001 276: 45662-45668. First Published on September 14, 2001; 10.1074/jbc.M105374200 [Abstract] [Full Text] [PDF]  

Marianne Santaguida, Qingming Ding, Ginette Bérubé, Mary Truscott, Peter Whyte, and Alain Nepveu

Phosphorylation of the CCAAT Displacement Protein (CDP)/Cux Transcription Factor by Cyclin A-Cdk1 Modulates Its DNA Binding Activity in G₂
J. Biol. Chem. 2001 276: 45780-45790. First Published on October 2, 2001; 10.1074/jbc.M107978200 [Abstract] [Full Text] [PDF]  

Hervé N. Kovacic, Kaikobad Irani, and Pascal J. Goldschmidt-Clermont

Redox Regulation of Human Rac1 Stability by the Proteasome in Human Aortic Endothelial Cells
J. Biol. Chem. 2001 276: 45856-45861. First Published on October 3, 2001; 10.1074/jbc.M107925200 [Abstract] [Full Text] [PDF]  

Gregory Raczniak, Hubert D. Becker, Bokkee Min, and Dieter Söll

A Single Amidotransferase Forms Asparaginyl-tRNA and Glutaminyl-tRNA in Chlamydia trachomatis
J. Biol. Chem. 2001 276: 45862-45867. First Published on October 3, 2001; 10.1074/jbc.M109494200 [Abstract] [Full Text] [PDF]  

Renee Dow, Joy Hendley, Andreja Pirkmaier, Elizabeth A. Musgrove, and Doris Germain

Retinoic Acid-mediated Growth Arrest Requires Ubiquitylation and Degradation of the F-box Protein Skp2
J. Biol. Chem. 2001 276: 45945-45951. First Published on October 10, 2001; 10.1074/jbc.M103593200 [Abstract] [Full Text] [PDF]  

Christelle Morris-Desbois, Stéphane Réty, Myriam Ferro, Jérôme Garin, and Pierre Jalinot

The Human Protein HSPC021 Interacts with Int-6 and Is Associated with Eukaryotic Translation Initiation Factor 3
J. Biol. Chem. 2001 276: 45988-45995. First Published on October 4, 2001; 10.1074/jbc.M104966200 [Abstract] [Full Text] [PDF]  

Béatrice Blanchard-Fillion, José M. Souza, Thomas Friel, George C. T. Jiang, Kent Vrana, Victor Sharov, Lorena Barrón, Christian Schöneich, Celia Quijano, Beatriz Alvarez, Rafael Radi, Serge Przedborski, Gayani S. Fernando, Joel Horwitz, and Harry Ischiropoulos

Nitration and Inactivation of Tyrosine Hydroxylase by Peroxynitrite
J. Biol. Chem. 2001 276: 46017-46023. First Published on October 5, 2001; 10.1074/jbc.M105564200 [Abstract] [Full Text] [PDF]  

Maria Tsirigotis, Mei Zhang, Roland K. Chiu, Bradly G. Wouters, and Douglas A. Gray

Sensitivity of Mammalian Cells Expressing Mutant Ubiquitin to Protein-damaging Agents
J. Biol. Chem. 2001 276: 46073-46078. First Published on October 11, 2001; 10.1074/jbc.M109023200 [Abstract] [Full Text] [PDF]  

Kiven E. Lukong, Volkan Seyrantepe, Karine Landry, Stéphanie Trudel, Ali Ahmad, William A. Gahl, Stéphane Lefrancois, Carlos R. Morales, and Alexey V. Pshezhetsky

Intracellular Distribution of Lysosomal Sialidase Is Controlled by the Internalization Signal in Its Cytoplasmic Tail
J. Biol. Chem. 2001 276: 46172-46181. First Published on September 24, 2001; 10.1074/jbc.M104547200 [Abstract] [Full Text] [PDF]  

Chun Chen, Qi Wang, Xiangdong Fang, Qin Xu, Chengwu Chi, and Jianxin Gu

Roles of Phytanoyl-CoA -Hydroxylase in Mediating the Expression of Human Coagulation Factor VIII
J. Biol. Chem. 2001 276: 46340-46346. First Published on September 26, 2001; 10.1074/jbc.M106124200 [Abstract] [Full Text] [PDF]  

Cornelia Gruendler, Yin Lin, Jennifer Farley, and Tongwen Wang

Proteasomal Degradation of Smad1 Induced by Bone Morphogenetic Proteins
J. Biol. Chem. 2001 276: 46533-46543. First Published on September 24, 2001; 10.1074/jbc.M105500200 [Abstract] [Full Text] [PDF]  

Tetsu Kamitani, Katsumi Kito, Taeko Fukuda-Kamitani, and Edward T. H. Yeh

Targeting of NEDD8 and Its Conjugates for Proteasomal Degradation by NUB1
J. Biol. Chem. 2001 276: 46655-46660. First Published on October 3, 2001; 10.1074/jbc.M108636200 [Abstract] [Full Text] [PDF]  

Genomics Proteomics and Bioinformatics:

Christian G. Huber, Anna-Maria Timperio, and Lello Zolla

Isoforms of Photosystem II Antenna Proteins in Different Plant Species Revealed by Liquid Chromatography-Electrospray Ionization Mass Spectrometry
J. Biol. Chem. 2001 276: 45755-45761. First Published on October 1, 2001; 10.1074/jbc.M106700200 [Abstract] [Full Text] [PDF]  

C. Kiong Ho and Stewart Shuman

Trypanosoma brucei RNA Triphosphatase. ANTIPROTOZOAL DRUG TARGET AND GUIDE TO EUKARYOTIC PHYLOGENY
J. Biol. Chem. 2001 276: 46182-46186. First Published on September 11, 2001; 10.1074/jbc.M108706200 [Abstract] [Full Text] [PDF]  

Mafalda Escobar-Henriques, Axelle Balguerie, Chistelle Monribot, Hélian Boucherie, and Bertrand Daignan-Fornier

Proteome Analysis and Morphological Studies Reveal Multiple Effects of the Immunosuppressive Drug Mycophenolic Acid Specifically Resulting from Guanylic Nucleotide Depletion
J. Biol. Chem. 2001 276: 46237-46242. First Published on September 4, 2001; 10.1074/jbc.M103416200 [Abstract] [Full Text] [PDF]  

Protein Structure and Folding:

Rolf Gurezka and Dieter Langosch

In Vitro Selection of Membrane-spanning Leucine Zipper Protein-Protein Interaction Motifs Using POSSYCCAT
J. Biol. Chem. 2001 276: 45580-45587. First Published on October 3, 2001; 10.1074/jbc.M105362200 [Abstract] [Full Text] [PDF]  

Helen M. Webb, Lloyd W. Ruddock, Rosalyn J. Marchant, Kim Jonas, and Peter Klappa

Interaction of the Periplasmic Peptidylprolyl cis-trans Isomerase SurA with Model Peptides. THE N-TERMINAL REGION OF SurA IS ESSENTIAL AND SUFFICIENT FOR PEPTIDE BINDING
J. Biol. Chem. 2001 276: 45622-45627. First Published on August 23, 2001; 10.1074/jbc.M107508200 [Abstract] [Full Text] [PDF]  

Rachel Wain, Thelma A. Pertinhez, Esther J. Tomlinson, Lin Hong, Christopher M. Dobson, Stuart J. Ferguson, and Lorna J. Smith

The Cytochrome c Fold Can Be Attained from a Compact Apo State by Occupancy of a Nascent Heme Binding Site
J. Biol. Chem. 2001 276: 45813-45817. First Published on October 2, 2001; 10.1074/jbc.M107572200 [Abstract] [Full Text] [PDF]  

Martin Bilej, Patrick De Baetselier, Els Van Dijck, Benoit Stijlemans, Alain Colige, and Alain Beschin

Distinct Carbohydrate Recognition Domains of an Invertebrate Defense Molecule Recognize Gram-negative and Gram-positive Bacteria
J. Biol. Chem. 2001 276: 45840-45847. First Published on October 3, 2001; 10.1074/jbc.M107220200 [Abstract] [Full Text] [PDF]  

Tina M. Misenheimer, Allison J. Hahr, Amy C. Harms, Douglas S. Annis, and Deane F. Mosher

Disulfide Connectivity of Recombinant C-terminal Region of Human Thrombospondin 2
J. Biol. Chem. 2001 276: 45882-45887. First Published on October 4, 2001; 10.1074/jbc.M104218200 [Abstract] [Full Text] [PDF]  

Robert Bussell, Jr. and David Eliezer

Residual Structure and Dynamics in Parkinson's Disease-associated Mutants of -Synuclein
J. Biol. Chem. 2001 276: 45996-46003. First Published on October 4, 2001; 10.1074/jbc.M106777200 [Abstract] [Full Text] [PDF]  

King Wong Leung, Yen-Chywan Liaw, Siu Chiu Chan, Hau Yi Lo, Faik N. Musayev, Jack Z.-W. Chen, Huey-Jen Fang, and Hueih Min Chen

Significance of Local Electrostatic Interactions in Staphylococcal Nuclease Studied by Site-directed Mutagenesis
J. Biol. Chem. 2001 276: 46039-46045. First Published on October 11, 2001; 10.1074/jbc.M106620200 [Abstract] [Full Text] [PDF]  

Giles Velarde, Robert C. Ford, Mark F. Rosenberg, and Simon J. Powis

Three-dimensional Structure of Transporter Associated with Antigen Processing (TAP) Obtained by Single Particle Image Analysis
J. Biol. Chem. 2001 276: 46054-46063. First Published on October 10, 2001; 10.1074/jbc.M108435200 [Abstract] [Full Text] [PDF]  

Anna Sokolova, Marc Malfois, Javier Caldentey, Dmitri I. Svergun, Michel H. J. Koch, Dennis H. Bamford, and Roman Tuma

Solution Structure of Bacteriophage PRD1 Vertex Complex
J. Biol. Chem. 2001 276: 46187-46195. First Published on September 27, 2001; 10.1074/jbc.M106848200 [Abstract] [Full Text] [PDF]  

Qianjin Liu, Thai-Yen Ling, Huey-Sheng Shieh, Frank E. Johnson, Jung San Huang, and Shuan Shian Huang

Identification of the High Affinity Binding Site in Transforming Growth Factor- Involved in Complex Formation with ₂-Macroglobulin. IMPLICATIONS REGARDING THE MOLECULAR MECHANISMS OF COMPLEX FORMATION BETWEEN ₂-MACROGLOBULIN AND GROWTH FACTORS, CYTOKINES, AND HORMONES
J. Biol. Chem. 2001 276: 46212-46218. First Published on October 2, 2001; 10.1074/jbc.M105177200 [Abstract] [Full Text] [PDF]  

Sergey A. Kozin, Gildas Bertho, Alexey K. Mazur, Hanitra Rabesona, Jean-Pierre Girault, Thomas Haertlé, Masayuki Takahashi, Pascale Debey, and Gaston Hui Bon Hoa

Sheep Prion Protein Synthetic Peptide Spanning Helix 1 and -Strand 2 (Residues 142-166) Shows -Hairpin Structure in Solution
J. Biol. Chem. 2001 276: 46364-46370. First Published on September 27, 2001; 10.1074/jbc.M108014200 [Abstract] [Full Text] [PDF]  

Valerie Blanc, Jeffrey O. Henderson, Susan Kennedy, and Nicholas O. Davidson

Mutagenesis of Apobec-1 Complementation Factor Reveals Distinct Domains That Modulate RNA Binding, Protein-Protein Interaction with Apobec-1, and Complementation of C to U RNA-editing Activity
J. Biol. Chem. 2001 276: 46386-46393. First Published on September 24, 2001; 10.1074/jbc.M107654200 [Abstract] [Full Text] [PDF]  

Mohammad Hassan Qureshi, Jonathan C. Yeung, Sau-Ching Wu, and Sui-Lam Wong

Development and Characterization of a Series of Soluble Tetrameric and Monomeric Streptavidin Muteins with Differential Biotin Binding Affinities
J. Biol. Chem. 2001 276: 46422-46428. First Published on October 2, 2001; 10.1074/jbc.M107398200 [Abstract] [Full Text] [PDF]  

Roger Vila, Imma Ponte, Maribel Collado, José Luis R. Arrondo, M. Angeles Jiménez, Manuel Rico, and Pedro Suau

DNA-induced -Helical Structure in the NH₂-terminal Domain of Histone H1
J. Biol. Chem. 2001 276: 46429-46435. First Published on October 2, 2001; 10.1074/jbc.M106952200 [Abstract] [Full Text] [PDF]  

Peter J. Greasley, Francesca Fanelli, Alexander Scheer, Liliane Abuin, Monique Nenniger-Tosato, Pier G. DeBenedetti, and Susanna Cotecchia

Mutational and Computational Analysis of the _1b-Adrenergic Receptor. INVOLVEMENT OF BASIC AND HYDROPHOBIC RESIDUES IN RECEPTOR ACTIVATION AND G PROTEIN COUPLING
J. Biol. Chem. 2001 276: 46485-46494. First Published on October 3, 2001; 10.1074/jbc.M105791200 [Abstract] [Full Text] [PDF] Supplemental Data  

Enzyme Catalysis and Regulation:

Alexandra Martins and Stewart Shuman

Mutational Analysis of Baculovirus Capping Enzyme Lef4 Delineates an Autonomous Triphosphatase Domain and Structural Determinants of Divalent Cation Specificity
J. Biol. Chem. 2001 276: 45522-45529. First Published on September 11, 2001; 10.1074/jbc.M107615200 [Abstract] [Full Text] [PDF]  

Tarlan G. Mamedov, Kensaku Suzuki, Kenji Miura, Ken-ichi Kucho, and Hideya Fukuzawa

Characteristics and Sequence of Phosphoglycolate Phosphatase from a Eukaryotic Green Alga Chlamydomonas reinhardtii
J. Biol. Chem. 2001 276: 45573-45579. First Published on October 1, 2001; 10.1074/jbc.M103882200 [Abstract] [Full Text] [PDF]  

Anupama Ahuja, Cristina Purcarea, Hedeel I. Guy, and David R. Evans

A Novel Carbamoyl-Phosphate Synthetase from Aquifex aeolicus
J. Biol. Chem. 2001 276: 45694-45703. First Published on September 26, 2001; 10.1074/jbc.M106382200 [Abstract] [Full Text] [PDF]  

Maria M. Corvi, Carrie-Lynn M. Soltys, and Luc G. Berthiaume

Regulation of Mitochondrial Carbamoyl-phosphate Synthetase 1 Activity by Active Site Fatty Acylation
J. Biol. Chem. 2001 276: 45704-45712. First Published on September 27, 2001; 10.1074/jbc.M102766200 [Abstract] [Full Text] [PDF]  

Donmienne Leung, Kate Schroder, Helen White, Ning-Xia Fang, Martin J. Stoermer, Giovanni Abbenante, Jennifer L. Martin, Paul R. Young, and David P. Fairlie

Activity of Recombinant Dengue 2 Virus NS3 Protease in the Presence of a Truncated NS2B Co-factor, Small Peptide Substrates, and Inhibitors
J. Biol. Chem. 2001 276: 45762-45771. First Published on October 1, 2001; 10.1074/jbc.M107360200 [Abstract] [Full Text] [PDF]  

Subray S. Hegde, Farah Javid-Majd, and John S. Blanchard

Overexpression and Mechanistic Analysis of Chromosomally Encoded Aminoglycoside 2'-N-Acetyltransferase (AAC(2')-Ic) from Mycobacterium tuberculosis
J. Biol. Chem. 2001 276: 45876-45881. First Published on October 4, 2001; 10.1074/jbc.M108810200 [Abstract] [Full Text] [PDF]  

Stefan Weiss, Rosetta Rossi, Maria-Antonietta Pellegrino, Roberto Bottinelli, and Michael A. Geeves

Differing ADP Release Rates from Myosin Heavy Chain Isoforms Define the Shortening Velocity of Skeletal Muscle Fibers
J. Biol. Chem. 2001 276: 45902-45908. First Published on October 5, 2001; 10.1074/jbc.M107434200 [Abstract] [Full Text] [PDF]  

Natalia Nemeria, Yan Yan, Zhen Zhang, Angela M. Brown, Palaniappa Arjunan, William Furey, John R. Guest, and Frank Jordan

Inhibition of the Escherichia coli Pyruvate Dehydrogenase Complex E1 Subunit and Its Tyrosine 177 Variants by Thiamin 2-Thiazolone and Thiamin 2-Thiothiazolone Diphosphates. EVIDENCE FOR REVERSIBLE TIGHT-BINDING INHIBITION
J. Biol. Chem. 2001 276: 45969-45978. First Published on October 2, 2001; 10.1074/jbc.M104116200 [Abstract] [Full Text] [PDF]  

David Maag, Christian Castro, Zhi Hong, and Craig E. Cameron

Hepatitis C Virus RNA-dependent RNA Polymerase (NS5B) as a Mediator of the Antiviral Activity of Ribavirin
J. Biol. Chem. 2001 276: 46094-46098. First Published on October 15, 2001; 10.1074/jbc.C100349200 [Abstract] [Full Text] [PDF]  

Jeremiah B. Frueauf, Miguel A. Ballicora, and Jack Preiss

Aspartate Residue 142 Is Important for Catalysis by ADP-glucose Pyrophosphorylase from Escherichia coli
J. Biol. Chem. 2001 276: 46319-46325. First Published on September 20, 2001; 10.1074/jbc.M107408200 [Abstract] [Full Text] [PDF]  

Zhen Zhang, Yang Yu, James M. Musser, and Timothy Palzkill

Amino Acid Sequence Determinants of Extended Spectrum Cephalosporin Hydrolysis by the Class C P99 -Lactamase
J. Biol. Chem. 2001 276: 46568-46574. First Published on October 8, 2001; 10.1074/jbc.M102757200 [Abstract] [Full Text] [PDF]  

Diane Thibeault, Roger Maurice, Louise Pilote, Daniel Lamarre, and Arnim Pause

In Vitro Characterization of a Purified NS2/3 Protease Variant of Hepatitis C Virus
J. Biol. Chem. 2001 276: 46678-46684. First Published on October 8, 2001; 10.1074/jbc.M108266200 [Abstract] [Full Text] [PDF]  

Metabolism and Bioenergetics:

Numsen Hail, Jr. and Reuben Lotan

Mitochondrial Respiration Is Uniquely Associated with the Prooxidant and Apoptotic Effects of N-(4-Hydroxyphenyl)retinamide
J. Biol. Chem. 2001 276: 45614-45621. First Published on August 23, 2001; 10.1074/jbc.M106559200 [Abstract] [Full Text] [PDF]  

Véronique Nogueira, Michel Rigoulet, Marie-Astrid Piquet, Anne Devin, Eric Fontaine, and Xavier M. Leverve

Mitochondrial Respiratory Chain Adjustment to Cellular Energy Demand
J. Biol. Chem. 2001 276: 46104-46110. First Published on September 28, 2001; 10.1074/jbc.M107425200 [Abstract] [Full Text] [PDF]  

Kunhong Xiao, Ananda Chandrasekaran, Linda Yu, and Chang-An Yu

Evidence for the Intertwined Dimer of the Cytochrome bc₁ Complex in Solution
J. Biol. Chem. 2001 276: 46125-46131. First Published on September 18, 2001; 10.1074/jbc.M107436200 [Abstract] [Full Text] [PDF]  

Françoise Levavasseur, Hiroko Miyadera, Jacinthe Sirois, Michel L. Tremblay, Kiyoshi Kita, Eric Shoubridge, and Siegfried Hekimi

Ubiquinone Is Necessary for Mouse Embryonic Development but Is Not Essential for Mitochondrial Respiration
J. Biol. Chem. 2001 276: 46160-46164. First Published on October 3, 2001; 10.1074/jbc.M108980200 [Abstract] [Full Text] [PDF]  

Masayuki Nakanishi, Chizuko Yatome, Norihisa Ishida, and Yukio Kitade

Putative ACP Phosphodiesterase Gene (acpD) Encodes an Azoreductase
J. Biol. Chem. 2001 276: 46394-46399. First Published on October 2, 2001; 10.1074/jbc.M104483200 [Abstract] [Full Text] [PDF]  

Glycobiology and Extracellular Matrices:

Tsutomu Iwamoto, Satoshi Fukumoto, Kazuhiro Kanaoka, Eiko Sakai, Mitsue Shibata, Emiko Fukumoto, Jin-ichi Inokuchi, Kogo Takamiya, Keiko Furukawa, Koichi Furukawa, Yuzo Kato, and Akio Mizuno

Lactosylceramide Is Essential for the Osteoclastogenesis Mediated by Macrophage-Colony-stimulating Factor and Receptor Activator of Nuclear Factor-B Ligand
J. Biol. Chem. 2001 276: 46031-46038. First Published on October 9, 2001; 10.1074/jbc.M104464200 [Abstract] [Full Text] [PDF]  

Lipids and Lipoproteins:

Anita K. Stannard, David R. Riddell, Sandra M. Sacre, Aristides D. Tagalakis, Claus Langer, Arnold von Eckardstein, Paul Cullen, Takis Athanasopoulos, George Dickson, and James S. Owen

Cell-derived Apolipoprotein E (ApoE) Particles Inhibit Vascular Cell Adhesion Molecule-1 (VCAM-1) Expression in Human Endothelial Cells
J. Biol. Chem. 2001 276: 46011-46016. First Published on October 5, 2001; 10.1074/jbc.M104812200 [Abstract] [Full Text] [PDF]  

Patty Siri, Ninfa Candela, Yuan-Li Zhang, Carol Ko, Sharif Eusufzai, Henry N. Ginsberg, and Li-Shin Huang

Post-transcriptional Stimulation of the Assembly and Secretion of Triglyceride-rich Apolipoprotein B Lipoproteins in a Mouse with Selective Deficiency of Brown Adipose Tissue, Obesity, and Insulin Resistance
J. Biol. Chem. 2001 276: 46064-46072. First Published on October 11, 2001; 10.1074/jbc.M108909200 [Abstract] [Full Text] [PDF]  

Andrey Frolov, Kalpana Srivastava, Dorit Daphna-Iken, Linton M. Traub, Jean E. Schaffer, and Daniel S. Ory

Cholesterol Overload Promotes Morphogenesis of a Niemann-Pick C (NPC)-like Compartment Independent of Inhibition of NPC1 or HE1/NPC2 Function
J. Biol. Chem. 2001 276: 46414-46421. First Published on September 24, 2001; 10.1074/jbc.M108099200 [Abstract] [Full Text] [PDF]  

Membrane Transport Structure Function and Biogenesis:

Karel Talavera, Mik Staes, Annelies Janssens, Norbert Klugbauer, Guy Droogmans, Franz Hofmann, and Bernd Nilius

Aspartate Residues of the Glu-Glu-Asp-Asp (EEDD) Pore Locus Control Selectivity and Permeation of the T-type Ca²⁺ Channel _1G
J. Biol. Chem. 2001 276: 45628-45635. First Published on August 28, 2001; 10.1074/jbc.M103047200 [Abstract] [Full Text] [PDF]  

Andreas Androutsellis-Theotokis, Farshid Ghassemi, and Gary Rudnick

A Conformationally Sensitive Residue on the Cytoplasmic Surface of Serotonin Transporter
J. Biol. Chem. 2001 276: 45933-45938. First Published on October 9, 2001; 10.1074/jbc.M107462200 [Abstract] [Full Text] [PDF]  

Ehud Sass, Eran Blachinsky, Sharon Karniely, and Ophry Pines

Mitochondrial and Cytosolic Isoforms of Yeast Fumarase Are Derivatives of a Single Translation Product and Have Identical Amino Termini
J. Biol. Chem. 2001 276: 46111-46117. First Published on October 3, 2001; 10.1074/jbc.M106061200 [Abstract] [Full Text] [PDF]  

Felix A. Ruiz, Norma Marchesini, Manfredo Seufferheld, Govindjee, and Roberto Docampo

The Polyphosphate Bodies of Chlamydomonas reinhardtii Possess a Proton-pumping Pyrophosphatase and Are Similar to Acidocalcisomes
J. Biol. Chem. 2001 276: 46196-46203. First Published on September 28, 2001; 10.1074/jbc.M105268200 [Abstract] [Full Text] [PDF]  

Sanjay K. Mishra, Nicole R. Agostinelli, Tom J. Brett, Ikuko Mizukami, Theodora S. Ross, and Linton M. Traub

Clathrin- and AP-2-binding Sites in HIP1 Uncover a General Assembly Role for Endocytic Accessory Proteins
J. Biol. Chem. 2001 276: 46230-46236. First Published on September 27, 2001; 10.1074/jbc.M108177200 [Abstract] [Full Text] [PDF]  

Kelly M. Weixel and Neil A. Bradbury

µ2 Binding Directs the Cystic Fibrosis Transmembrane Conductance Regulator to the Clathrin-mediated Endocytic Pathway
J. Biol. Chem. 2001 276: 46251-46259. First Published on September 17, 2001; 10.1074/jbc.M104545200 [Abstract] [Full Text] [PDF]  

Amparo M. Estepa, Ana I. Rocha, Vicente Mas, Luis Pérez, Jose Antonio Encinar, Elena Nuñez, Asia Fernandez, Jose Manuel Gonzalez Ros, Francisco Gavilanes, and Julio M. Coll

A Protein G Fragment from the Salmonid Viral Hemorrhagic Septicemia Rhabdovirus Induces Cell-to-Cell Fusion and Membrane Phosphatidylserine Translocation at Low pH
J. Biol. Chem. 2001 276: 46268-46275. First Published on October 4, 2001; 10.1074/jbc.M108682200 [Abstract] [Full Text] [PDF]  

Noam Zelcer, Tohru Saeki, Glen Reid, Jos H. Beijnen, and Piet Borst

Characterization of Drug Transport by the Human Multidrug Resistance Protein 3 (ABCC3)
J. Biol. Chem. 2001 276: 46400-46407. First Published on October 1, 2001; 10.1074/jbc.M107041200 [Abstract] [Full Text] [PDF]  

John Santiago, Gisila R. Guzmán, Legier V. Rojas, Ricardo Marti, Guillermo A. Asmar-Rovira, Luis F. Santana, Mark McNamee, and José A. Lasalde-Dominicci

Probing the Effects of Membrane Cholesterol in the Torpedo californica Acetylcholine Receptor and the Novel Lipid-exposed Mutation C418W in Xenopus Oocytes
J. Biol. Chem. 2001 276: 46523-46532. First Published on September 20, 2001; 10.1074/jbc.M104563200 [Abstract] [Full Text] [PDF]  

Chuan-ju Liu, Sulayman D. Dib-Hajj, Joel A. Black, John Greenwood, Zheng Lian, and Stephen G. Waxman

Direct Interaction with Contactin Targets Voltage-gated Sodium Channel Na_v1.9/NaN to the Cell Membrane
J. Biol. Chem. 2001 276: 46553-46561. First Published on October 1, 2001; 10.1074/jbc.M108699200 [Abstract] [Full Text] [PDF]  

Nikolaj Spodsberg, Marwan Alfalah, and Hassan Y. Naim

Characteristics and Structural Requirements of Apical Sorting of the Rat Growth Hormone through the O-Glycosylated Stalk Region of Intestinal Sucrase-isomaltase
J. Biol. Chem. 2001 276: 46597-46604. First Published on September 27, 2001; 10.1074/jbc.M108187200 [Abstract] [Full Text] [PDF]  

Aslihan Aydemir-Koksoy, Joel Abramowitz, and Julius C. Allen

Ouabain-induced Signaling and Vascular Smooth Muscle Cell Proliferation
J. Biol. Chem. 2001 276: 46605-46611. First Published on September 28, 2001; 10.1074/jbc.M106178200 [Abstract] [Full Text] [PDF]  

Adriana C. C. Girardi, Brenda C. Degray, Tamas Nagy, Daniel Biemesderfer, and Peter S. Aronson

Association of Na⁺-H⁺ Exchanger Isoform NHE3 and Dipeptidyl Peptidase IV in the Renal Proximal Tubule
J. Biol. Chem. 2001 276: 46671-46677. First Published on October 5, 2001; 10.1074/jbc.M106897200 [Abstract] [Full Text] [PDF]  

Mechanisms Of Signal Transduction:

Bradley E. Sturgeon, Richard E. Glover, Yeong-Renn Chen, Leo T. Burka, and Ronald P. Mason

Tyrosine Iminoxyl Radical Formation from Tyrosyl Radical/Nitric Oxide and Nitrosotyrosine
J. Biol. Chem. 2001 276: 45516-45521. First Published on September 10, 2001; 10.1074/jbc.M106835200 [Abstract] [Full Text] [PDF]  

Michael D. Southall, Jason S. Isenberg, Harikrishna Nakshatri, Qiaofang Yi, Yong Pei, Dan F. Spandau, and Jeffrey B. Travers

The Platelet-activating Factor Receptor Protects Epidermal Cells from Tumor Necrosis Factor (TNF) and TNF-related Apoptosis-inducing Ligand-induced Apoptosis through an NF-B-dependent Process
J. Biol. Chem. 2001 276: 45548-45554. First Published on September 24, 2001; 10.1074/jbc.M105978200 [Abstract] [Full Text] [PDF]  

Áine Kelly, Aileen Lynch, Emily Vereker, Yvonne Nolan, Patrice Queenan, Elizabeth Whittaker, Luke A. J. O'Neill, and Marina A. Lynch

The Anti-inflammatory Cytokine, Interleukin (IL)-10, Blocks the Inhibitory Effect of IL-1 on Long Term Potentiation. A ROLE FOR JNK
J. Biol. Chem. 2001 276: 45564-45572. First Published on October 1, 2001; 10.1074/jbc.M108757200 [Abstract] [Full Text] [PDF]  

Paul O. Hassa, Marcela Covic, Sameez Hasan, Ralph Imhof, and Michael O. Hottiger

The Enzymatic and DNA Binding Activity of PARP-1 Are Not Required for NF-B Coactivator Function
J. Biol. Chem. 2001 276: 45588-45597. First Published on October 4, 2001; 10.1074/jbc.M106528200 [Abstract] [Full Text] [PDF]  

Hua Zhang and Kathleen A. Gallo

Autoinhibition of Mixed Lineage Kinase 3 through Its Src Homology 3 Domain
J. Biol. Chem. 2001 276: 45598-45603. First Published on October 4, 2001; 10.1074/jbc.M107176200 [Abstract] [Full Text] [PDF]  

Chiho Kanamaru, Hiroshi Yasuda, Masafumi Takeda, Namiki Ueda, Junko Suzuki, Tomohiro Tsuchida, Hirosato Mashima, Hirohide Ohnishi, and Toshiro Fujita

Smad7 Is Induced by Norepinephrine and Protects Rat Hepatocytes from Activin A-induced Growth Inhibition
J. Biol. Chem. 2001 276: 45636-45641. First Published on September 10, 2001; 10.1074/jbc.M105302200 [Abstract] [Full Text] [PDF]  

Maria Paola Martelli, Jonathan Boomer, Ming Bu, and Barbara E. Bierer

T Cell Regulation of p62^dok (Dok1) Association with Crk-L
J. Biol. Chem. 2001 276: 45654-45661. First Published on September 11, 2001; 10.1074/jbc.M105777200 [Abstract] [Full Text] [PDF]  

Zsuzsa Bauer, Lourdes Gómez-Gómez, Thomas Boller, and Georg Felix

Sensitivity of Different Ecotypes and Mutants of Arabidopsis thaliana toward the Bacterial Elicitor Flagellin Correlates with the Presence of Receptor-binding Sites
J. Biol. Chem. 2001 276: 45669-45676. First Published on September 19, 2001; 10.1074/jbc.M102390200 [Abstract] [Full Text] [PDF]  

Irina Woldman, Louisa Varinou, Katrin Ramsauer, Birgit Rapp, and Thomas Decker

The Stat1 Binding Motif of the Interferon- Receptor Is Sufficient to Mediate Stat5 Activation and Its Repression by SOCS3
J. Biol. Chem. 2001 276: 45722-45728. First Published on September 27, 2001; 10.1074/jbc.M105320200 [Abstract] [Full Text] [PDF]  

Yibang Chen, Barney Yoo, Jay B. Lee, Gezhi Weng, and Ravi Iyengar

The Signal Transfer Regions of G_s
J. Biol. Chem. 2001 276: 45751-45754. First Published on September 28, 2001; 10.1074/jbc.M107191200 [Abstract] [Full Text] [PDF]  

Yongle Guo, Toumy Guettouche, Mary Fenna, Frank Boellmann, William B. Pratt, David O. Toft, David F. Smith, and Richard Voellmy

Evidence for a Mechanism of Repression of Heat Shock Factor 1 Transcriptional Activity by a Multichaperone Complex
J. Biol. Chem. 2001 276: 45791-45799. First Published on October 2, 2001; 10.1074/jbc.M105931200 [Abstract] [Full Text] [PDF]  

Julie Perroy, Gustavo J. Gutierrez, Vincent Coulon, Joel Bockaert, Jean-Pilippe Pin, and Laurent Fagni

The C Terminus of the Metabotropic Glutamate Receptor Subtypes 2 and 7 Specifies the Receptor Signaling Pathways
J. Biol. Chem. 2001 276: 45800-45805. First Published on October 2, 2001; 10.1074/jbc.M106876200 [Abstract] [Full Text] [PDF]  

Seung Hyun Yoo, Young Soo Oh, Moon Kyung Kang, Yang Hoon Huh, Seung Ho So, Hyung Seon Park, and Hee Yun Park

Localization of Three Types of the Inositol 1,4,5-Trisphosphate Receptor/Ca²⁺ Channel in the Secretory Granules and Coupling with the Ca²⁺ Storage Proteins Chromogranins A and B
J. Biol. Chem. 2001 276: 45806-45812. First Published on October 2, 2001; 10.1074/jbc.M107532200 [Abstract] [Full Text] [PDF]  

M. Pia Arrate, Jose M. Rodriguez, Tuan M. Tran, Tommy A. Brock, and Sonia A. Cunningham

Cloning of Human Junctional Adhesion Molecule 3 (JAM3) and Its Identification as the JAM2 Counter-receptor
J. Biol. Chem. 2001 276: 45826-45832. First Published on October 4, 2001; 10.1074/jbc.M105972200 [Abstract] [Full Text] [PDF]  

Melanie A. Galea, Alexandra Eleftheriou, and Beric R. Henderson

ARM Domain-dependent Nuclear Import of Adenomatous Polyposis Coli Protein Is Stimulated by the B56 Subunit of Protein Phosphatase 2A
J. Biol. Chem. 2001 276: 45833-45839. First Published on October 3, 2001; 10.1074/jbc.M107149200 [Abstract] [Full Text] [PDF]  

Jason T. Snyder, Kent L. Rossman, Mark A. Baumeister, Wendy M. Pruitt, David P. Siderovski, Channing J. Der, Mark A. Lemmon, and John Sondek

Quantitative Analysis of the Effect of Phosphoinositide Interactions on the Function of Dbl Family Proteins
J. Biol. Chem. 2001 276: 45868-45875. First Published on September 27, 2001; 10.1074/jbc.M106731200 [Abstract] [Full Text] [PDF]  

Mingui Fu, Jifeng Zhang, Xiaojun Zhu, David E. Myles, Timothy M. Willson, Xuedong Liu, and Yuqing E. Chen

Peroxisome Proliferator-activated Receptor Inhibits Transforming Growth Factor -induced Connective Tissue Growth Factor Expression in Human Aortic Smooth Muscle Cells by Interfering with Smad3
J. Biol. Chem. 2001 276: 45888-45894. First Published on October 5, 2001; 10.1074/jbc.M105490200 [Abstract] [Full Text] [PDF]  

Lawrence M. Pfeffer, Chuan He Yang, Aruna Murti, Shirley A. McCormack, Mary Jane Viar, Ramesh M. Ray, and Leonard R. Johnson

Polyamine Depletion Induces Rapid NF-B Activation in IEC-6 Cells
J. Biol. Chem. 2001 276: 45909-45913. First Published on October 5, 2001; 10.1074/jbc.M108097200 [Abstract] [Full Text] [PDF]  

Erica L. Vielhaber, Deborah Duricka, Katharine S. Ullman, and David M. Virshup

Nuclear Export of Mammalian PERIOD Proteins
J. Biol. Chem. 2001 276: 45921-45927. First Published on October 8, 2001; 10.1074/jbc.M107726200 [Abstract] [Full Text] [PDF]  

Cyrile Anne Curat, Maresa Eck, Xavier Dervillez, and Wolfgang F. Vogel

Mapping of Epitopes in Discoidin Domain Receptor 1 Critical for Collagen Binding
J. Biol. Chem. 2001 276: 45952-45958. First Published on October 11, 2001; 10.1074/jbc.M104360200 [Abstract] [Full Text] [PDF]  

Larry W. Shepard, Ming Yang, Ping Xie, Darren D. Browning, Tatyana Voyno-Yasenetskaya, Tohru Kozasa, and Richard D. Ye

Constitutive Activation of NF-B and Secretion of Interleukin-8 Induced by the G Protein-coupled Receptor of Kaposi's Sarcoma-associated Herpesvirus Involve G₁₃ and RhoA
J. Biol. Chem. 2001 276: 45979-45987. First Published on October 4, 2001; 10.1074/jbc.M104783200 [Abstract] [Full Text] [PDF]  

Yi-Hung Lin and Hsin-Fang Yang-Yen

The Osteopontin-CD44 Survival Signal Involves Activation of the Phosphatidylinositol 3-Kinase/Akt Signaling Pathway
J. Biol. Chem. 2001 276: 46024-46030. First Published on October 5, 2001; 10.1074/jbc.M105132200 [Abstract] [Full Text] [PDF]  

Yasushige Kashima, Takashi Miki, Tadao Shibasaki, Nobuaki Ozaki, Masaru Miyazaki, Hideki Yano, and Susumu Seino

Critical Role of cAMP-GEFII·Rim2 Complex in Incretin-potentiated Insulin Secretion
J. Biol. Chem. 2001 276: 46046-46053. First Published on October 11, 2001; 10.1074/jbc.M108378200 [Abstract] [Full Text] [PDF]  

Romel Somwar, Wenyan Niu, David Y. Kim, Gary Sweeney, Varinder K. Randhawa, Carol Huang, Toolsie Ramlal, and Amira Klip

Differential Effects of Phosphatidylinositol 3-Kinase Inhibition on Intracellular Signals Regulating GLUT4 Translocation and Glucose Transport
J. Biol. Chem. 2001 276: 46079-46087. First Published on October 11, 2001; 10.1074/jbc.M109093200 [Abstract] [Full Text] [PDF]  

Rita Vaiskunaite, Tohru Kozasa, and Tatyana A. Voyno-Yasenetskaya

Interaction between the G Subunit of Heterotrimeric G₁₂ Protein and Hsp90 Is Required for G₁₂ Signaling
J. Biol. Chem. 2001 276: 46088-46093. First Published on October 11, 2001; 10.1074/jbc.M108711200 [Abstract] [Full Text] [PDF]  

Ayaka Saka, Mitsuhiro Abe, Hiroyuki Okano, Masayo Minemura, Hiroshi Qadota, Takahiko Utsugi, Akihisa Mino, Kazuma Tanaka, Yoshimi Takai, and Yoshikazu Ohya

Complementing Yeast rho1 Mutation Groups with Distinct Functional Defects
J. Biol. Chem. 2001 276: 46165-46171. First Published on September 26, 2001; 10.1074/jbc.M103805200 [Abstract] [Full Text] [PDF]  

Helene Boeuf, Karine Merienne, Sylvie Jacquot, David Duval, Maria Zeniou, Charlotte Hauss, Beatrice Reinhardt, Yolande Huss-Garcia, Andree Dierich, David A. Frank, Andre Hanauer, and Claude Kedinger

The Ribosomal S6 Kinases, cAMP-responsive Element-binding, and STAT3 Proteins Are Regulated by Different Leukemia Inhibitory Factor Signaling Pathways in Mouse Embryonic Stem Cells
J. Biol. Chem. 2001 276: 46204-46211. First Published on October 1, 2001; 10.1074/jbc.M106718200 [Abstract] [Full Text] [PDF]  

Fabian Docagne, Nathalie Colloc'h, Vanessa Bougueret, Martine Page, Jérôme Paput, Marina Tripier, Patrick Dutartre, Eric T. MacKenzie, Alain Buisson, Sylviane Komesli, and Denis Vivien

A Soluble Transforming Growth Factor- (TGF-) Type I Receptor Mimics TGF- Responses
J. Biol. Chem. 2001 276: 46243-46250. First Published on September 5, 2001; 10.1074/jbc.M010915200 [Abstract] [Full Text] [PDF]  

Toshihisa Hatae, Masayuki Wada, Chieko Yokoyama, Manabu Shimonishi, and Tadashi Tanabe

Prostacyclin-dependent Apoptosis Mediated by PPAR
J. Biol. Chem. 2001 276: 46260-46267. First Published on September 10, 2001; 10.1074/jbc.M107180200 [Abstract] [Full Text] [PDF]  

Koichi Miura, Shoko Miyazawa, Shuichi Furuta, Junji Mitsushita, Keiju Kamijo, Hiroshi Ishida, Toru Miki, Kazumi Suzukawa, James Resau, Terry D. Copeland, and Tohru Kamata

The Sos1-Rac1 Signaling. POSSIBLE INVOLVEMENT OF A VACUOLAR H⁺-ATPase E SUBUNIT
J. Biol. Chem. 2001 276: 46276-46283. First Published on September 17, 2001; 10.1074/jbc.M102387200 [Abstract] [Full Text] [PDF]  

Richard H. Kim, Kathleen C. Flanders, Stephanie Birkey Reffey, Lisa A. Anderson, Colin S. Duckett, Neil D. Perkins, and Anita B. Roberts

SNIP1 Inhibits NF-B Signaling by Competing for Its Binding to the C/H1 Domain of CBP/p300 Transcriptional Co-activators
J. Biol. Chem. 2001 276: 46297-46304. First Published on September 20, 2001; 10.1074/jbc.M103819200 [Abstract] [Full Text] [PDF]  

Manuela Klingler-Hoffmann, Michelle T. Fodero-Tavoletti, Kazuhiko Mishima, Yoshitaka Narita, Webster K. Cavenee, Frank B. Furnari, H.-J. Su Huang, and Tony Tiganis

The Protein Tyrosine Phosphatase TCPTP Suppresses the Tumorigenicity of Glioblastoma Cells Expressing a Mutant Epidermal Growth Factor Receptor
J. Biol. Chem. 2001 276: 46313-46318. First Published on August 20, 2001; 10.1074/jbc.M106571200 [Abstract] [Full Text] [PDF]  

M. Javad Aman, Annie-Carole Tosello-Trampont, and Kodimangalam Ravichandran

FcRIIB1/SHIP-mediated Inhibitory Signaling in B Cells Involves Lipid Rafts
J. Biol. Chem. 2001 276: 46371-46378. First Published on September 24, 2001; 10.1074/jbc.M104069200 [Abstract] [Full Text] [PDF]  

Yona Goldshmit, Shlomit Erlich, and Ronit Pinkas-Kramarski

Neuregulin Rescues PC12-ErbB4 Cells from Cell Death Induced by H₂O₂. REGULATION OF REACTIVE OXYGEN SPECIES LEVELS BY PHOSPHATIDYLINOSITOL 3-KINASE
J. Biol. Chem. 2001 276: 46379-46385. First Published on October 4, 2001; 10.1074/jbc.M105637200 [Abstract] [Full Text] [PDF]  

Andrea Todisco, Nonthalee Pausawasdi, Saravanan Ramamoorthy, John Del Valle, Rebecca W. Van Dyke, and Frederick K. Askari

Functional Role of Protein Kinase B/Akt in Gastric Acid Secretion
J. Biol. Chem. 2001 276: 46436-46444. First Published on September 19, 2001; 10.1074/jbc.M009645200 [Abstract] [Full Text] [PDF]  

Jennifer J. Westendorf

The Formin/Diaphanous-related Protein, FHOS, Interacts with Rac1 and Activates Transcription from the Serum Response Element
J. Biol. Chem. 2001 276: 46453-46459. First Published on October 4, 2001; 10.1074/jbc.M105162200 [Abstract] [Full Text] [PDF]  

Isabelle Gross, Bhramdeo Bassit, Miriam Benezra, and Jonathan D. Licht

Mammalian Sprouty Proteins Inhibit Cell Growth and Differentiation by Preventing Ras Activation
J. Biol. Chem. 2001 276: 46460-46468. First Published on October 3, 2001; 10.1074/jbc.M108234200 [Abstract] [Full Text] [PDF]  

Michelle A. Emrick, Andrew N. Hoofnagle, Aaron S. Miller, Lynn F. Ten Eyck, and Natalie G. Ahn

Constitutive Activation of Extracellular Signal-regulated Kinase 2 by Synergistic Point Mutations
J. Biol. Chem. 2001 276: 46469-46479. First Published on October 8, 2001; 10.1074/jbc.M107708200 [Abstract] [Full Text] [PDF]  

Håkan Muyderman, Mikael Ängehagen, Mats Sandberg, Ulrika Björklund, Torsten Olsson, Elisabeth Hansson, and Michael Nilsson

₁-Adrenergic Modulation of Metabotropic Glutamate Receptor-induced Calcium Oscillations and Glutamate Release in Astrocytes
J. Biol. Chem. 2001 276: 46504-46514. First Published on September 28, 2001; 10.1074/jbc.M103849200 [Abstract] [Full Text] [PDF]  

Masaaki Nomura, Akira Kaji, Zhiwei He, Wei-Ya Ma, Ken-ichi Miyamoto, Chung S. Yang, and Zigang Dong

Inhibitory Mechanisms of Tea Polyphenols on the Ultraviolet B-activated Phosphatidylinositol 3-Kinase-dependent Pathway
J. Biol. Chem. 2001 276: 46624-46631. First Published on October 8, 2001; 10.1074/jbc.M107897200 [Abstract] [Full Text] [PDF]  

Silvia Grisendi, Beatrice Chambraud, Ivan Gout, Paolo M. Comoglio, and Tiziana Crepaldi

Ligand-regulated Binding of FAP68 to the Hepatocyte Growth Factor Receptor
J. Biol. Chem. 2001 276: 46632-46638. First Published on September 24, 2001; 10.1074/jbc.M104323200 [Abstract] [Full Text] [PDF]  

Frank C. Kischkel, David A. Lawrence, Antoine Tinel, Heidi LeBlanc, Arvind Virmani, Peter Schow, Adi Gazdar, John Blenis, David Arnott, and Avi Ashkenazi

Death Receptor Recruitment of Endogenous Caspase-10 and Apoptosis Initiation in the Absence of Caspase-8
J. Biol. Chem. 2001 276: 46639-46646. First Published on October 2, 2001; 10.1074/jbc.M105102200 [Abstract] [Full Text] [PDF]  

Molecular Basis Of Cell and Developmental Biology:

Elena G. Yarmola, Shefal Parikh, and Michael R. Bubb

Formation and Implications of a Ternary Complex of Profilin, Thymosin ₄, and Actin
J. Biol. Chem. 2001 276: 45555-45563. First Published on September 28, 2001; 10.1074/jbc.M105723200 [Abstract] [Full Text] [PDF]  

Gordon D. Strachan, Ravikumar Rallapalli, Bruna Pucci, Toulouse P. Lafond, and David J. Hall

A Transcriptionally Inactive E2F-1 Targets the MDM Family of Proteins for Proteolytic Degradation
J. Biol. Chem. 2001 276: 45677-45685. First Published on September 21, 2001; 10.1074/jbc.M103765200 [Abstract] [Full Text] [PDF]  

Günther Richter, Martha Hayden-Ledbetter, Markus Irgang, Jeffrey A. Ledbetter, Jörg Westermann, Ida Körner, Kerstin Daemen, Edward A. Clark, Alexandra Aicher, and Antonio Pezzutto

Tumor Necrosis Factor- Regulates the Expression of Inducible Costimulator Receptor Ligand on CD34⁺ Progenitor Cells during Differentiation into Antigen Presenting Cells
J. Biol. Chem. 2001 276: 45686-45693. First Published on September 24, 2001; 10.1074/jbc.M108509200 [Abstract] [Full Text] [PDF]  

Alexei Iakhiaev, Usha R. Pendurthi, and L. Vijaya Mohan Rao

Active Site Blockade of Factor VIIa Alters Its Intracellular Distribution
J. Biol. Chem. 2001 276: 45895-45901. First Published on October 4, 2001; 10.1074/jbc.M107603200 [Abstract] [Full Text] [PDF]  

Stefan D. Gross, Andrea L. Lewellyn, and James L. Maller

A Constitutively Active Form of the Protein Kinase p90^Rsk1 Is Sufficient to Trigger the G₂/M Transition in Xenopus Oocytes
J. Biol. Chem. 2001 276: 46099-46103. First Published on October 18, 2001; 10.1074/jbc.C100496200 [Abstract] [Full Text] [PDF]  

Shinjiro Imai, Hiroyuki Tezuka, Yuko Furuhashi, Riho Muto, and Koichiro Fujita

A Factor of Inducing IgE from a Filarial Parasite Is an Agonist of Human CD40
J. Biol. Chem. 2001 276: 46118-46124. First Published on October 8, 2001; 10.1074/jbc.M104581200 [Abstract] [Full Text] [PDF]  

Dwight J. Klemm, Peter A. Watson, Maria G. Frid, Edward C. Dempsey, Jerome Schaack, Lillester A. Colton, Albina Nesterova, Kurt R. Stenmark, and Jane E.-B. Reusch

cAMP Response Element-binding Protein Content Is a Molecular Determinant of Smooth Muscle Cell Proliferation and Migration
J. Biol. Chem. 2001 276: 46132-46141. First Published on September 17, 2001; 10.1074/jbc.M104769200 [Abstract] [Full Text] [PDF]  

Peter A. Watson, Albina Nesterova, Charles F. Burant, Dwight J. Klemm, and Jane E.-B. Reusch

Diabetes-related Changes in cAMP Response Element-binding Protein Content Enhance Smooth Muscle Cell Proliferation and Migration
J. Biol. Chem. 2001 276: 46142-46150. First Published on September 17, 2001; 10.1074/jbc.M104770200 [Abstract] [Full Text] [PDF]  

Alex Levine, Beatrice Belenghi, Hila Damari-Weisler, and David Granot

Vesicle-associated Membrane Protein of Arabidopsis Suppresses Bax-induced Apoptosis in Yeast Downstream of Oxidative Burst
J. Biol. Chem. 2001 276: 46284-46289. First Published on September 10, 2001; 10.1074/jbc.M107375200 [Abstract] [Full Text] [PDF]  

Xiu-Huai Liu, R. John Collier, and Richard J. Youle

Inhibition of Axotomy-induced Neuronal Apoptosis by Extracellular Delivery of a Bcl-XL Fusion Protein
J. Biol. Chem. 2001 276: 46326-46332. First Published on September 26, 2001; 10.1074/jbc.M108930200 [Abstract] [Full Text] [PDF]  

Biaoru Li, Wei Zhang, Ging Chan, Agnes Jancso-Radek, Shunhe Liu, and Michael A. Weiss

Human Sex Reversal Due to Impaired Nuclear Localization of SRY. A CLINICAL CORRELATION
J. Biol. Chem. 2001 276: 46480-46484. First Published on October 18, 2001; 10.1074/jbc.C100388200 [Abstract] [Full Text] [PDF]  

Francesca Gori, Paola Divieti, and Marie B. Demay

Cloning and Characterization of a Novel WD-40 Repeat Protein That Dramatically Accelerates Osteoblastic Differentiation
J. Biol. Chem. 2001 276: 46515-46522. First Published on September 10, 2001; 10.1074/jbc.M105757200 [Abstract] [Full Text] [PDF]  

G. Mark Xu, Tabo Sikaneta, Brandon M. Sullivan, Qunhao Zhang, Michele Andreucci, Thilo Stehle, Iain Drummond, and M. Amin Arnaout

Polycystin-1 Interacts with Intermediate Filaments
J. Biol. Chem. 2001 276: 46544-46552. First Published on October 1, 2001; 10.1074/jbc.M107828200 [Abstract] [Full Text] [PDF]  

Jade K. Forwood, Vincent Harley, and David A. Jans

The C-terminal Nuclear Localization Signal of the Sex-determining Region Y (SRY) High Mobility Group Domain Mediates Nuclear Import through Importin 1
J. Biol. Chem. 2001 276: 46575-46582. First Published on September 4, 2001; 10.1074/jbc.M101668200 [Abstract] [Full Text] [PDF]  

Irina P. Artemenko, Dong Zhao, Dale B. Hales, Karen H. Hales, and Colin R. Jefcoate

Mitochondrial Processing of Newly Synthesized Steroidogenic Acute Regulatory Protein (StAR), but Not Total StAR, Mediates Cholesterol Transfer to Cytochrome P450 Side Chain Cleavage Enzyme in Adrenal Cells
J. Biol. Chem. 2001 276: 46583-46596. First Published on September 28, 2001; 10.1074/jbc.M107815200 [Abstract] [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.