JBC Focus on PI3-Kinase with Echelon
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 Table of Contents: Jan 25 2002; 277 (4)   [Index by Author]  [Cover Figure and Caption]
       Minireviews
       Accelerated Publications
       DNA: Replication Repair and Recombination
       Genes: Structure and Regulation
       RNA: Structure Metabolism and Catalysis
       Protein Synthesis Post-Translation Modification and Degradation
       Protein Structure and Folding
       Enzyme Catalysis and Regulation
       Metabolism and Bioenergetics
       Glycobiology and Extracellular Matrices
       Lipids and Lipoproteins
       Membrane Transport Structure Function and Biogenesis
       Mechanisms Of Signal Transduction
       Molecular Basis Of Cell and Developmental Biology
       Additions and Corrections
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Minireviews:

Michael J. Welsh, Margaret P. Price, and Jinghui Xie
Biochemical Basis of Touch Perception: Mechanosensory Function of Degenerin/Epithelial Na+ Channels
J. Biol. Chem. 2002 277: 2369-2372. First Published on November 8, 2001; 10.1074/jbc.R100060200 [Full Text] [PDF]  

Accelerated Publications:

Yaohuang Ke and Elizabeth C. Theil
An mRNA Loop/Bulge in the Ferritin Iron-responsive Element Forms in Vivo and Was Detected by Radical Probing with Cu-1,10-phenantholine and Iron Regulatory Protein Footprinting
J. Biol. Chem. 2002 277: 2373-2376. First Published on November 19, 2001; 10.1074/jbc.C100614200 [Abstract] [Full Text] [PDF]  

Jianyong Wang, Jeanne A. Stuckey, Matthew J. Wishart, and Jack E. Dixon
A Unique Carbohydrate Binding Domain Targets the Lafora Disease Phosphatase to Glycogen
J. Biol. Chem. 2002 277: 2377-2380. First Published on December 5, 2001; 10.1074/jbc.C100686200 [Abstract] [Full Text] [PDF]  

Pei-Jung Lu, Xiao Zhen Zhou, Yih-Cherng Liou, Joseph P. Noel, and Kun Ping Lu
Critical Role of WW Domain Phosphorylation in Regulating Phosphoserine Binding Activity and Pin1 Function
J. Biol. Chem. 2002 277: 2381-2384. First Published on November 26, 2001; 10.1074/jbc.C100228200 [Abstract] [Full Text] [PDF]  

DNA: Replication Repair and Recombination:

Mark G. Alexandrow, Marion Ritzi, Alexander Pemov, and Joyce L. Hamlin
A Potential Role for Mini-chromosome Maintenance (MCM) Proteins in Initiation at the Dihydrofolate Reductase Replication Origin
J. Biol. Chem. 2002 277: 2702-2708. First Published on November 26, 2001; 10.1074/jbc.M108118200 [Abstract] [Full Text] [PDF]  

Saija Haapa-Paananen, Hannu Rita, and Harri Savilahti
DNA Transposition of Bacteriophage Mu. A QUANTITATIVE ANALYSIS OF TARGET SITE SELECTION IN VITRO
J. Biol. Chem. 2002 277: 2843-2851. First Published on November 7, 2001; 10.1074/jbc.M108044200 [Abstract] [Full Text] [PDF]  

Sarah Burgess, Pawel Jaruga, M. L. Dodson, Miral Dizdaroglu, and R. Stephen Lloyd
Determination of Active Site Residues in Escherichia coli Endonuclease VIII
J. Biol. Chem. 2002 277: 2938-2944. First Published on November 15, 2001; 10.1074/jbc.M110499200 [Abstract] [Full Text] [PDF]  

Mamuka Kvaratskhelia, Benjamin N. Wardleworth, Charles S. Bond, Jonathan M. Fogg, David M. J. Lilley, and Malcolm F. White
Holliday Junction Resolution Is Modulated by Archaeal Chromatin Components in Vitro
J. Biol. Chem. 2002 277: 2992-2996. First Published on November 14, 2001; 10.1074/jbc.M109496200 [Abstract] [Full Text] [PDF]  

Susanne Mårtensson and Ola Hammarsten
DNA-dependent Protein Kinase Catalytic Subunit. STRUCTURAL REQUIREMENTS FOR KINASE ACTIVATION BY DNA ENDS
J. Biol. Chem. 2002 277: 3020-3029. First Published on November 7, 2001; 10.1074/jbc.M106711200 [Abstract] [Full Text] [PDF]  

Yuji Masuda, Mamoru Takahashi, Saburo Fukuda, Masaharu Sumii, and Kenji Kamiya
Mechanisms of dCMP Transferase Reactions Catalyzed by Mouse Rev1 Protein
J. Biol. Chem. 2002 277: 3040-3046. First Published on November 15, 2001; 10.1074/jbc.M110149200 [Abstract] [Full Text] [PDF]  

Genes: Structure and Regulation:

Yoon-Kwang Lee and David D. Moore
Dual Mechanisms for Repression of the Monomeric Orphan Receptor Liver Receptor Homologous Protein-1 by the Orphan Small Heterodimer Partner
J. Biol. Chem. 2002 277: 2463-2467. First Published on October 19, 2001; 10.1074/jbc.M105161200 [Abstract] [Full Text] [PDF]  

Fan Yeung, Wai K. Law, Ching-Hua Yeh, Jennifer J. Westendorf, Ye Zhang, Ruoxiang Wang, Chinghai Kao, and Leland W. K. Chung
Regulation of Human Osteocalcin Promoter in Hormone-independent Human Prostate Cancer Cells
J. Biol. Chem. 2002 277: 2468-2476. First Published on October 29, 2001; 10.1074/jbc.M105947200 [Abstract] [Full Text] [PDF]  

Dale E. A. Lewis and Sankar Adhya
In Vitro Repression of the gal Promoters by GalR and HU Depends on the Proper Helical Phasing of the Two Operators
J. Biol. Chem. 2002 277: 2498-2504. First Published on November 7, 2001; 10.1074/jbc.M108456200 [Abstract] [Full Text] [PDF]  

Rosalind Gusterson, Bhawanjit Brar, David Faulkes, Antonio Giordano, John Chrivia, and David Latchman
The Transcriptional Co-activators CBP and p300 Are Activated via Phenylephrine through the p42/p44 MAPK Cascade
J. Biol. Chem. 2002 277: 2517-2524. First Published on November 8, 2001; 10.1074/jbc.M104626200 [Abstract] [Full Text] [PDF]  

Janeen H. Trembley, Dongli Hu, Li-Chung Hsu, Cho-Yau Yeung, Clive Slaughter, Jill M. Lahti, and Vincent J. Kidd
PITSLRE p110 Protein Kinases Associate with Transcription Complexes and Affect Their Activity
J. Biol. Chem. 2002 277: 2589-2596. First Published on November 14, 2001; 10.1074/jbc.M109755200 [Abstract] [Full Text] [PDF]  

Cuihua Liu and Craig T. Martin
Promoter Clearance by T7 RNA Polymerase. INITIAL BUBBLE COLLAPSE AND TRANSCRIPT DISSOCIATION MONITORED BY BASE ANALOG FLUORESCENCE
J. Biol. Chem. 2002 277: 2725-2731. First Published on November 1, 2001; 10.1074/jbc.M108856200 [Abstract] [Full Text] [PDF]  

Laurent Maillet and Martine A. Collart
Interaction between Not1p, a Component of the Ccr4-Not Complex, a Global Regulator of Transcription, and Dhh1p, a Putative RNA Helicase
J. Biol. Chem. 2002 277: 2835-2842. First Published on November 5, 2001; 10.1074/jbc.M107979200 [Abstract] [Full Text] [PDF]  

Fanny Jaulin-Bastard, Jean-Pierre Arsanto, André Le Bivic, Christel Navarro, Frédéric Vély, Hiroko Saito, Sylvie Marchetto, Mechthild Hatzfeld, Marie-Josée Santoni, Daniel Birnbaum, and Jean-Paul Borg
Interaction between Erbin and a Catenin-related Protein in Epithelial Cells
J. Biol. Chem. 2002 277: 2869-2875. First Published on November 15, 2001; 10.1074/jbc.M109652200 [Abstract] [Full Text] [PDF]  

Heidi R. Kast, Bryan Goodwin, Paul T. Tarr, Stacey A. Jones, Andrew M. Anisfeld, Catherine M. Stoltz, Peter Tontonoz, Steve Kliewer, Timothy M. Willson, and Peter A. Edwards
Regulation of Multidrug Resistance-associated Protein 2 (ABCC2) by the Nuclear Receptors Pregnane X Receptor, Farnesoid X-activated Receptor, and Constitutive Androstane Receptor
J. Biol. Chem. 2002 277: 2908-2915. First Published on November 12, 2001; 10.1074/jbc.M109326200 [Abstract] [Full Text] [PDF]  

Sun Gwan Hwang, Daeyoup Lee, Jiyun Kim, Taegun Seo, and Joonho Choe
Human Papillomavirus Type 16 E7 Binds to E2F1 and Activates E2F1-driven Transcription in a Retinoblastoma Protein-independent Manner
J. Biol. Chem. 2002 277: 2923-2930. First Published on November 16, 2001; 10.1074/jbc.M109113200 [Abstract] [Full Text] [PDF]  

Ming Yi, Guo-Xia Tong, Barbara Murry, and Carole R. Mendelson
Role of CBP/p300 and SRC-1 in Transcriptional Regulation of the Pulmonary Surfactant Protein-A (SP-A) Gene by Thyroid Transcription Factor-1 (TTF-1)
J. Biol. Chem. 2002 277: 2997-3005. First Published on November 16, 2001; 10.1074/jbc.M109793200 [Abstract] [Full Text] [PDF]  

Nicola A. Hawkes, Gabriel Otero, G. Sebastiaan Winkler, Nick Marshall, Michael E. Dahmus, Daniel Krappmann, Claus Scheidereit, Claire L. Thomas, Giampietro Schiavo, Hediye Erdjument-Bromage, Paul Tempst, and Jesper Q. Svejstrup
Purification and Characterization of the Human Elongator Complex
J. Biol. Chem. 2002 277: 3047-3052. First Published on November 19, 2001; 10.1074/jbc.M110445200 [Abstract] [Full Text] [PDF]  

RNA: Structure Metabolism and Catalysis:

Nancy D. Rodgers, Zuoren Wang, and Megerditch Kiledjian
Characterization and Purification of a Mammalian Endoribonuclease Specific for the alpha -Globin mRNA
J. Biol. Chem. 2002 277: 2597-2604. First Published on November 15, 2001; 10.1074/jbc.M108330200 [Abstract] [Full Text] [PDF]  

Kathleen E. McGinness and Gerald F. Joyce
Substitution of Ribonucleotides in the T7 RNA Polymerase Promoter Element
J. Biol. Chem. 2002 277: 2987-2991. First Published on November 9, 2001; 10.1074/jbc.M108820200 [Abstract] [Full Text] [PDF]  

Protein Synthesis Post-Translation Modification and Degradation:

Erik Westein, Cécile V. Denis, Bonno N. Bouma, and Peter J. Lenting
The alpha -Chains of C4b-binding Protein Mediate Complex Formation with Low Density Lipoprotein Receptor-related Protein
J. Biol. Chem. 2002 277: 2511-2516. First Published on November 8, 2001; 10.1074/jbc.M102293200 [Abstract] [Full Text] [PDF]  

Evgeni G. Ponimaskin, Martin Heine, Lara Joubert, Michèle Sebben, Ulf Bickmeyer, Diethelm W. Richter, and Aline Dumuis
The 5-Hydroxytryptamine(4a) Receptor Is Palmitoylated at Two Different Sites, and Acylation Is Critically Involved in Regulation of Receptor Constitutive Activity
J. Biol. Chem. 2002 277: 2534-2546. First Published on November 12, 2001; 10.1074/jbc.M106529200 [Abstract] [Full Text] [PDF]  

Scott C. Galasinski, Donna F. Louie, Kristen K. Gloor, Katheryn A. Resing, and Natalie G. Ahn
Global Regulation of Post-translational Modifications on Core Histones
J. Biol. Chem. 2002 277: 2579-2588. First Published on November 14, 2001; 10.1074/jbc.M107894200 [Abstract] [Full Text] [PDF]  

Hsing-Yin Liu, Bradley S. Nefsky, and Nancy C. Walworth
The Ded1 DEAD Box Helicase Interacts with Chk1 and Cdc2
J. Biol. Chem. 2002 277: 2637-2643. First Published on November 15, 2001; 10.1074/jbc.M109016200 [Abstract] [Full Text] [PDF]  

Maria Pavlaki, Jian Cao, Michelle Hymowitz, Wen-Tien Chen, Wadie Bahou, and Stanley Zucker
A Conserved Sequence within the Propeptide Domain of Membrane Type 1 Matrix Metalloproteinase Is Critical for Function as an Intramolecular Chaperone
J. Biol. Chem. 2002 277: 2740-2749. First Published on November 9, 2001; 10.1074/jbc.M108987200 [Abstract] [Full Text] [PDF]  

Youngsoo Kim, Sanggu Kim, Thomas N. Earnest, and Wim G. J. Hol
Precursor Structure of Cephalosporin Acylase. INSIGHTS INTO AUTOPROTEOLYTIC ACTIVATION IN A NEW N-TERMINAL HYDROLASE FAMILY
J. Biol. Chem. 2002 277: 2823-2829. First Published on November 8, 2001; 10.1074/jbc.M108888200 [Abstract] [Full Text] [PDF]  

Rodolfo Murillas, Kimberly S. Simms, Shigetsugu Hatakeyama, Allan M. Weissman, and Michael R. Kuehn
Identification of Developmentally Expressed Proteins That Functionally Interact with Nedd4 Ubiquitin Ligase
J. Biol. Chem. 2002 277: 2897-2907. First Published on November 20, 2001; 10.1074/jbc.M110047200 [Abstract] [Full Text] [PDF]  

Yin-Yuan Mo, Yanni Yu, Zhiyuan Shen, and William T. Beck
Nucleolar Delocalization of Human Topoisomerase I in Response to Topotecan Correlates with Sumoylation of the Protein
J. Biol. Chem. 2002 277: 2958-2964. First Published on November 14, 2001; 10.1074/jbc.M108263200 [Abstract] [Full Text] [PDF]  

Protein Structure and Folding:

Jan Guerin, Yonghua Sheng, Stephen Reddel, G. Michael Iverson, Michael G. Chapman, and Steven A Krilis
Heparin Inhibits the Binding of beta 2-glycoprotein I to Phospholipids and Promotes the Plasmin-mediated Inactivation of This Blood Protein. ELUCIDATION OF THE CONSEQUENCES OF THE TWO BIOLOGICAL EVENTS IN PATIENTS WITH THE ANTI-PHOSPHOLIPID SYNDROME
J. Biol. Chem. 2002 277: 2644-2649. First Published on November 15, 2001; 10.1074/jbc.M110176200 [Abstract] [Full Text] [PDF]  

Hirokazu Kouguchi, Toshihiro Watanabe, Yoshimasa Sagane, Hiroyuki Sunagawa, and Tohru Ohyama
In Vitro Reconstitution of the Clostridium botulinum Type D Progenitor Toxin
J. Biol. Chem. 2002 277: 2650-2656. First Published on November 16, 2001; 10.1074/jbc.M106762200 [Abstract] [Full Text] [PDF]  

Amélie Faubert, Angela Samaan, and Jacques Thibodeau
Functional Analysis of Tryptophans alpha 62 and beta 120 on HLA-DM
J. Biol. Chem. 2002 277: 2750-2755. First Published on November 16, 2001; 10.1074/jbc.M110300200 [Abstract] [Full Text] [PDF]  

Matthew D. Baker, Anastassios C. Papageorgiou, Richard W. Titball, Julie Miller, Sarah White, Bryan Lingard, Jeong Jin Lee, David Cavanagh, Michael A. Kehoe, John H. Robinson, and K. Ravi Acharya
Structural and Functional Role of Threonine 112 in a Superantigen Staphylococcus aureus Enterotoxin B
J. Biol. Chem. 2002 277: 2756-2762. First Published on November 9, 2001; 10.1074/jbc.M109369200 [Abstract] [Full Text] [PDF]  

Savvas N. Savvides, Michael Scheiwein, Catharina C. Böhme, Gavin E. Arteel, P. Andrew Karplus, Katja Becker, and R. Heiner Schirmer
Crystal Structure of the Antioxidant Enzyme Glutathione Reductase Inactivated by Peroxynitrite
J. Biol. Chem. 2002 277: 2779-2784. First Published on November 8, 2001; 10.1074/jbc.M108190200 [Abstract] [Full Text] [PDF]  

Jennifer M. Burns, Daniel J. Dairaghi, Mary Deitz, Monica Tsang, and Thomas J. Schall
Comprehensive Mapping of Poxvirus vCCI Chemokine-binding Protein. EXPANDED RANGE OF LIGAND INTERACTIONS AND UNUSUAL DISSOCIATION KINETICS
J. Biol. Chem. 2002 277: 2785-2789. First Published on November 5, 2001; 10.1074/jbc.M109884200 [Abstract] [Full Text] [PDF]  

Atsuko Satoh, Jong-Keun Kim, Ikuko Miyahara, Bart Devreese, Isabel Vandenberghe, Ayse Hacisalihoglu, Toshihide Okajima, Shun'ichi Kuroda, Osao Adachi, Johannis A. Duine, Jozef Van Beeumen, Katsuyuki Tanizawa, and Ken Hirotsu
Crystal Structure of Quinohemoprotein Amine Dehydrogenase from Pseudomonas putida. IDENTIFICATION OF A NOVEL QUINONE COFACTOR ENCAGED BY MULTIPLE THIOETHER CROSS-BRIDGES
J. Biol. Chem. 2002 277: 2830-2834. First Published on November 9, 2001; 10.1074/jbc.M109090200 [Abstract] [Full Text] [PDF]  

D. Borden Lacy, Michael Mourez, Alexandre Fouassier, and R. John Collier
Mapping the Anthrax Protective Antigen Binding Site on the Lethal and Edema Factors
J. Biol. Chem. 2002 277: 3006-3010. First Published on November 19, 2001; 10.1074/jbc.M109997200 [Abstract] [Full Text] [PDF]  

Enzyme Catalysis and Regulation:

Masashi Unno, James F. Christian, Theodore Sjodin, David E. Benson, Iain D. G. Macdonald, Stephen G. Sligar, and Paul M. Champion
Complex Formation of Cytochrome P450cam with Putidaredoxin. EVIDENCE FOR PROTEIN-SPECIFIC INTERACTIONS INVOLVING THE PROXIMAL THIOLATE LIGAND
J. Biol. Chem. 2002 277: 2547-2553. First Published on November 12, 2001; 10.1074/jbc.M108917200 [Abstract] [Full Text] [PDF]  

Steven D. Breazeale, Anthony A. Ribeiro, and Christian R. H. Raetz
Oxidative Decarboxylation of UDP-Glucuronic Acid in Extracts of Polymyxin-resistant Escherichia coli. ORIGIN OF LIPID A SPECIES MODIFIED WITH 4-AMINO-4-DEOXY-L-ARABINOSE
J. Biol. Chem. 2002 277: 2886-2896. First Published on November 8, 2001; 10.1074/jbc.M109377200 [Abstract] [Full Text] [PDF]  

Metabolism and Bioenergetics:

Lise Rauscher, Dominique Expert, Berthold F. Matzanke, and Alfred X. Trautwein
Chrysobactin-dependent Iron Acquisition in Erwinia chrysanthemi. FUNCTIONAL STUDY OF A HOMOLOG OF THE ESCHERICHIA COLI FERRIC ENTEROBACTIN ESTERASE
J. Biol. Chem. 2002 277: 2385-2395. First Published on November 1, 2001; 10.1074/jbc.M107530200 [Abstract] [Full Text] [PDF]  

Eleonora Ford, Martin N. Hughes, and Peter Wardman
The Reaction of Superoxide Radicals with S-Nitrosoglutathione and the Products of Its Reductive Heterolysis
J. Biol. Chem. 2002 277: 2430-2436. First Published on November 14, 2001; 10.1074/jbc.M109310200 [Abstract] [Full Text] [PDF]  

Eulàlia Montell, Carlos Lerín, Christopher B. Newgard, and Anna M. Gómez-Foix
Effects of Modulation of Glycerol Kinase Expression on Lipid and Carbohydrate Metabolism in Human Muscle Cells
J. Biol. Chem. 2002 277: 2682-2686. First Published on November 19, 2001; 10.1074/jbc.M107227200 [Abstract] [Full Text] [PDF]  

Yoshimasa Nakamura, Qing Feng, Takeshi Kumagai, Koji Torikai, Hajime Ohigashi, Toshihiko Osawa, Noriko Noguchi, Etsuo Niki, and Koji Uchida
Ebselen, a Glutathione Peroxidase Mimetic Seleno-organic Compound, as a Multifunctional Antioxidant. IMPLICATION FOR INFLAMMATION-ASSOCIATED CARCINOGENESIS
J. Biol. Chem. 2002 277: 2687-2694. First Published on November 19, 2001; 10.1074/jbc.M109641200 [Abstract] [Full Text] [PDF]  

Susana Cadenas, Karim S. Echtay, James A. Harper, Mika B. Jekabsons, Julie A. Buckingham, Evelyn Grau, Alejandro Abuin, Helen Chapman, John C. Clapham, and Martin D. Brand
The Basal Proton Conductance of Skeletal Muscle Mitochondria from Transgenic Mice Overexpressing or Lacking Uncoupling Protein-3
J. Biol. Chem. 2002 277: 2773-2778. First Published on November 13, 2001; 10.1074/jbc.M109736200 [Abstract] [Full Text] [PDF]  

Poul Erik Jensen, Lisa Rosgaard, Jürgen Knoetzel, and Henrik Vibe Scheller
Photosystem I Activity Is Increased in the Absence of the PSI-G Subunit
J. Biol. Chem. 2002 277: 2798-2803. First Published on November 13, 2001; 10.1074/jbc.M110448200 [Abstract] [Full Text] [PDF]  

Glycobiology and Extracellular Matrices:

Stefan T. Hepbildikler, Roger Sandhoff, Melanie Kölzer, Richard L. Proia, and Konrad Sandhoff
Physiological Substrates for Human Lysosomal beta -Hexosaminidase S
J. Biol. Chem. 2002 277: 2562-2572. First Published on November 13, 2001; 10.1074/jbc.M105457200 [Abstract] [Full Text] [PDF]  

Paul Bornstein, Vanessa Walsh, Jennifer Tullis, Emily Stainbrook, John F. Bateman, and Sheriar G. Hormuzdi
The Globular Domain of the Proalpha 1(I) N-Propeptide Is Not Required for Secretion, Processing by Procollagen N-Proteinase, or Fibrillogenesis of Type I Collagen in Mice
J. Biol. Chem. 2002 277: 2605-2613. First Published on November 8, 2001; 10.1074/jbc.M106181200 [Abstract] [Full Text] [PDF]  

Liwen Chen, Yaojiong Wu, Vivian Lee, Chris Kiani, Mark E. Adams, Yeqi Yao, and Burton B. Yang
The Folded Modules of Aggrecan G3 Domain Exert Two Separable Functions in Glycosaminoglycan Modification and Product Secretion
J. Biol. Chem. 2002 277: 2657-2665. First Published on November 19, 2001; 10.1074/jbc.M101153200 [Abstract] [Full Text] [PDF]  

Shih-Che Sue, Kun-Yi Chien, Wei-Ning Huang, Joseph K. Abraham, Kuan-Ming Chen, and Wen-guey Wu
Heparin Binding Stabilizes the Membrane-bound Form of Cobra Cardiotoxin
J. Biol. Chem. 2002 277: 2666-2673. First Published on November 19, 2001; 10.1074/jbc.M104887200 [Abstract] [Full Text] [PDF]  

Lipids and Lipoproteins:

Paola Milla, Karin Athenstaedt, Franca Viola, Simonetta Oliaro-Bosso, Sepp D. Kohlwein, Günther Daum, and Gianni Balliano
Yeast Oxidosqualene Cyclase (Erg7p) Is a Major Component of Lipid Particles
J. Biol. Chem. 2002 277: 2406-2412. First Published on November 12, 2001; 10.1074/jbc.M104195200 [Abstract] [Full Text] [PDF]  

Hiroki Tsuruoka, Weerapan Khovidhunkit, Barbara E. Brown, Joachim W. Fluhr, Peter M. Elias, and Kenneth R. Feingold
Scavenger Receptor Class B Type I Is Expressed in Cultured Keratinocytes and Epidermis. REGULATION IN RESPONSE TO CHANGES IN CHOLESTEROL HOMEOSTASIS AND BARRIER REQUIREMENTS
J. Biol. Chem. 2002 277: 2916-2922. First Published on November 13, 2001; 10.1074/jbc.M106445200 [Abstract] [Full Text] [PDF]  

Membrane Transport Structure Function and Biogenesis:

Kees Venema, Francisco J. Quintero, José M. Pardo, and Juan Pedro Donaire
The Arabidopsis Na+/H+ Exchanger AtNHX1 Catalyzes Low Affinity Na+ and K+ Transport in Reconstituted Liposomes
J. Biol. Chem. 2002 277: 2413-2418. First Published on November 13, 2001; 10.1074/jbc.M105043200 [Abstract] [Full Text] [PDF]  

Tomoki Suzuki, Shiroh Futaki, Miki Niwa, Seigo Tanaka, Kunihiro Ueda, and Yukio Sugiura
Possible Existence of Common Internalization Mechanisms among Arginine-rich Peptides
J. Biol. Chem. 2002 277: 2437-2443. First Published on November 15, 2001; 10.1074/jbc.M110017200 [Abstract] [Full Text] [PDF]  

Chava Kimchi-Sarfaty, Judith Kasir, Suresh V. Ambudkar, and Hannah Rahamimoff
Transport Activity and Surface Expression of the Na+-Ca2+ Exchanger NCX1 Are Inhibited by the Immunosuppressive Agent Cyclosporin A and by the Nonimmunosuppressive Agent PSC833
J. Biol. Chem. 2002 277: 2505-2510. First Published on November 7, 2001; 10.1074/jbc.M109154200 [Abstract] [Full Text] [PDF]  

Kelly Keenan Curtis and Patricia M. Kane
Novel Vacuolar H+-ATPase Complexes Resulting from Overproduction of Vma5p and Vma13p
J. Biol. Chem. 2002 277: 2716-2724. First Published on November 20, 2001; 10.1074/jbc.M107777200 [Abstract] [Full Text] [PDF]  

David A. Sweeney, Anirban Siddhanta, and Dennis Shields
Fragmentation and Re-assembly of the Golgi Apparatus in Vitro. A REQUIREMENT FOR PHOSPHATIDIC ACID AND PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE SYNTHESIS
J. Biol. Chem. 2002 277: 3030-3039. First Published on November 9, 2001; 10.1074/jbc.M104639200 [Abstract] [Full Text] [PDF]  

Mechanisms Of Signal Transduction:

Tomoshige Kino, Olga Slobodskaya, George N. Pavlakis, and George P. Chrousos
Nuclear Receptor Coactivator p160 Proteins Enhance the HIV-1 Long Terminal Repeat Promoter by Bridging Promoter-bound Factors and the Tat-P-TEFb Complex
J. Biol. Chem. 2002 277: 2396-2405. First Published on November 9, 2001; 10.1074/jbc.M106312200 [Abstract] [Full Text] [PDF]  

Olga Ostrovsky, Bluma Berman, John Gallagher, Barbara Mulloy, David G. Fernig, Maryse Delehedde, and Dina Ron
Differential Effects of Heparin Saccharides on the Formation of Specific Fibroblast Growth Factor (FGF) and FGF Receptor Complexes
J. Biol. Chem. 2002 277: 2444-2453. First Published on November 19, 2001; 10.1074/jbc.M108540200 [Abstract] [Full Text] [PDF]  

Qiang Ma and Krista Kinneer
Chemoprotection by Phenolic Antioxidants. INHIBITION OF TUMOR NECROSIS FACTOR alpha INDUCTION IN MACROPHAGES
J. Biol. Chem. 2002 277: 2477-2484. First Published on November 2, 2001; 10.1074/jbc.M106685200 [Abstract] [Full Text] [PDF]  

Bradley Saville, Hetti Poukka, Mark Wormke, Olli A. Jänne, Jorma J. Palvimo, Matthew Stoner, Ismael Samudio, and Stephen Safe
Cooperative Coactivation of Estrogen Receptor alpha in ZR-75 Human Breast Cancer Cells by SNURF and TATA-binding Protein
J. Biol. Chem. 2002 277: 2485-2497. First Published on November 5, 2001; 10.1074/jbc.M109021200 [Abstract] [Full Text] [PDF]  

O. Jameel Shah, Jorge A. Iniguez-Lluhi, Angela Romanelli, Scot R. Kimball, and Leonard S. Jefferson
The Activated Glucocorticoid Receptor Modulates Presumptive Autoregulation of Ribosomal Protein S6 Protein Kinase, p70 S6K
J. Biol. Chem. 2002 277: 2525-2533. First Published on November 8, 2001; 10.1074/jbc.M105935200 [Abstract] [Full Text] [PDF]  

Jonathan P. Godbout, James Pesavento, Matthew E. Hartman, Scott R. Manson, and Gregory G. Freund
Methylglyoxal Enhances Cisplatin-induced Cytotoxicity by Activating Protein Kinase Cdelta
J. Biol. Chem. 2002 277: 2554-2561. First Published on November 13, 2001; 10.1074/jbc.M100385200 [Abstract] [Full Text] [PDF]  

Hee-Sae Park, Mi-Sung Kim, Sung-Ho Huh, Jihyun Park, Jongkyeong Chung, Sang Sun Kang, and Eui-Ju Choi
Akt (Protein Kinase B) Negatively Regulates SEK1 by Means of Protein Phosphorylation
J. Biol. Chem. 2002 277: 2573-2578. First Published on November 13, 2001; 10.1074/jbc.M110299200 [Abstract] [Full Text] [PDF]  

Hiromichi Fujino, Kimberly A. West, and John W. Regan
Phosphorylation of Glycogen Synthase Kinase-3 and Stimulation of T-cell Factor Signaling following Activation of EP2 and EP4 Prostanoid Receptors by Prostaglandin E2
J. Biol. Chem. 2002 277: 2614-2619. First Published on November 12, 2001; 10.1074/jbc.M109440200 [Abstract] [Full Text] [PDF]  

Joshua M. Kruger, Takayasu Fukushima, Vera Cherepanov, Niels Borregaard, Carola Loeve, Christina Shek, Kalpana Sharma, A. Keith Tanswell, Chung-Wai Chow, and Gregory P. Downey
Protein-tyrosine Phosphatase MEG2 Is Expressed by Human Neutrophils. LOCALIZATION TO THE PHAGOSOME AND ACTIVATION BY POLYPHOSPHOINOSITIDES
J. Biol. Chem. 2002 277: 2620-2628. First Published on November 15, 2001; 10.1074/jbc.M104550200 [Abstract] [Full Text] [PDF]  

Céline Tárrega, Carmen Blanco-Aparicio, Juan José Muñoz, and Rafael Pulido
Two Clusters of Residues at the Docking Groove of Mitogen-activated Protein Kinases Differentially Mediate Their Functional Interaction with the Tyrosine Phosphatases PTP-SL and STEP
J. Biol. Chem. 2002 277: 2629-2636. First Published on November 15, 2001; 10.1074/jbc.M108874200 [Abstract] [Full Text] [PDF]  

Kari E. Fladmark, Odd T. Brustugun, Gunnar Mellgren, Camilla Krakstad, Roald Bøe, Olav K. Vintermyr, Howard Schulman, and Stein O. Døskeland
Ca2+/Calmodulin-dependent Protein Kinase II Is Required for Microcystin-induced Apoptosis
J. Biol. Chem. 2002 277: 2804-2811. First Published on November 16, 2001; 10.1074/jbc.M109049200 [Abstract] [Full Text] [PDF]  

John T. Seykora, Lijuan Mei, G. Paolo Dotto, and Paul L. Stein
`Srcasm: a Novel Src Activating and Signaling Molecule
J. Biol. Chem. 2002 277: 2812-2822. First Published on November 15, 2001; 10.1074/jbc.M106813200 [Abstract] [Full Text] [PDF]  

Andrew J. Boileau, J. Glen Newell, and Cynthia Czajkowski
GABAA Receptor beta 2 Tyr97 and Leu99 Line the GABA-binding Site. INSIGHTS INTO MECHANISMS OF AGONIST AND ANTAGONIST ACTIONS
J. Biol. Chem. 2002 277: 2931-2937. First Published on November 15, 2001; 10.1074/jbc.M109334200 [Abstract] [Full Text] [PDF]  

Petia P. Simeonova, Shiyi Wang, Tracy Hulderman, and Michael I. Luster
c-Src-dependent Activation of the Epidermal Growth Factor Receptor and Mitogen-activated Protein Kinase Pathway by Arsenic. ROLE IN CARCINOGENESIS
J. Biol. Chem. 2002 277: 2945-2950. First Published on November 26, 2001; 10.1074/jbc.M109136200 [Abstract] [Full Text] [PDF]  

Keitaro Tsuji, Kiyohisa Mizumoto, Tadanori Yamochi, Ikuo Nishimoto, and Masaaki Matsuoka
Differential Effect of ik3-1/Cables on p53- and p73-induced Cell Death
J. Biol. Chem. 2002 277: 2951-2957. First Published on November 12, 2001; 10.1074/jbc.M108535200 [Abstract] [Full Text] [PDF]  

Warwick S. Nesbitt, Suhasini Kulkarni, Simon Giuliano, Isaac Goncalves, Sacha M. Dopheide, Cindy L. Yap, Ian S. Harper, Hatem H. Salem, and Shaun P. Jackson
Distinct Glycoprotein Ib/V/IX and Integrin alpha IIbbeta 3-dependent Calcium Signals Cooperatively Regulate Platelet Adhesion under Flow
J. Biol. Chem. 2002 277: 2965-2972. First Published on November 16, 2001; 10.1074/jbc.M110070200 [Abstract] [Full Text] [PDF]  

Jean-François Côté, Ping Lin Chung, Jean-François Théberge, Maxime Hallé, Susan Spencer, Laurence A. Lasky, and Michel L. Tremblay
PSTPIP Is a Substrate of PTP-PEST and Serves as a Scaffold Guiding PTP-PEST Toward a Specific Dephosphorylation of WASP
J. Biol. Chem. 2002 277: 2973-2986. First Published on November 15, 2001; 10.1074/jbc.M106428200 [Abstract] [Full Text] [PDF]  

Hong Chen, Darren Locke, Ying Liu, Changdong Liu, and Mark L. Kahn
The Platelet Receptor GPVI Mediates Both Adhesion and Signaling Responses to Collagen in a Receptor Density-dependent Fashion
J. Biol. Chem. 2002 277: 3011-3019. First Published on November 26, 2001; 10.1074/jbc.M109714200 [Abstract] [Full Text] [PDF]  

Constantinos G. Broustas, Nicholas Grammatikakis, Masumi Eto, Paul Dent, David L. Brautigan, and Usha Kasid
Phosphorylation of the Myosin-binding Subunit of Myosin Phosphatase by Raf-1 and Inhibition of Phosphatase Activity
J. Biol. Chem. 2002 277: 3053-3059. First Published on November 21, 2001; 10.1074/jbc.M106343200 [Abstract] [Full Text] [PDF]  

Molecular Basis Of Cell and Developmental Biology:

Simon D. X. Chuong, Robert T. Mullen, and Douglas G. Muench
Identification of a Rice RNA- and Microtubule-binding Protein as the Multifunctional Protein, a Peroxisomal Enzyme Involved in the beta -Oxidation of Fatty Acids
J. Biol. Chem. 2002 277: 2419-2429. First Published on November 12, 2001; 10.1074/jbc.M109510200 [Abstract] [Full Text] [PDF]  

Casey W. Wright and Rollie J. Clem
Sequence Requirements for Hid Binding and Apoptosis Regulation in the Baculovirus Inhibitor of Apoptosis Op-IAP. Hid BINDS Op-IAP IN A MANNER SIMILAR TO Smac BINDING OF XIAP
J. Biol. Chem. 2002 277: 2454-2462. First Published on November 20, 2001; 10.1074/jbc.M110500200 [Abstract] [Full Text] [PDF]  

Viola Calabrò, Gelsomina Mansueto, Tiziana Parisi, Maria Vivo, Raffaele A. Calogero, and Girolama La Mantia
The Human MDM2 Oncoprotein Increases the Transcriptional Activity and the Protein Level of the p53 Homolog p63
J. Biol. Chem. 2002 277: 2674-2681. First Published on November 19, 2001; 10.1074/jbc.M107173200 [Abstract] [Full Text] [PDF]  

Linda Gilbert, Xiaofei He, Paul Farmer, Janet Rubin, Hicham Drissi, Andre J. van Wijnen, Jane B. Lian, Gary S. Stein, and Mark S. Nanes
Expression of the Osteoblast Differentiation Factor RUNX2 (Cbfa1/AML3/Pebp2alpha A) Is Inhibited by Tumor Necrosis Factor-alpha
J. Biol. Chem. 2002 277: 2695-2701. First Published on November 26, 2001; 10.1074/jbc.M106339200 [Abstract] [Full Text] [PDF]  

Kirsten Falk, Julie M. Lau, Laura Santambrogio, Viviana Marin Esteban, Fabiola Puentes, Olaf Rötzschke, and Jack L. Strominger
Ligand Exchange of Major Histocompatibility Complex Class II Proteins Is Triggered by H-bond Donor Groups of Small Molecules
J. Biol. Chem. 2002 277: 2709-2715. First Published on October 15, 2001; 10.1074/jbc.M109098200 [Abstract] [Full Text] [PDF]  

Hidenobu Kawamura, Yusuke Tomozoe, Tadayuki Akagi, Daisuke Kamei, Michiru Ochiai, and Michiyuki Yamada
Identification of the Nucleocytoplasmic Shuttling Sequence of Heterogeneous Nuclear Ribonucleoprotein D-like Protein JKTBP and Its Interaction with mRNA
J. Biol. Chem. 2002 277: 2732-2739. First Published on November 8, 2001; 10.1074/jbc.M108477200 [Abstract] [Full Text] [PDF]  

Hirohide Iwasaki, Kazuyoshi Chiba, Tsuyoshi Uchiyama, Fumio Yoshikawa, Fumiko Suzuki, Masako Ikeda, Teiichi Furuichi, and Katsuhiko Mikoshiba
Molecular Characterization of the Starfish Inositol 1,4,5-Trisphosphate Receptor and Its Role during Oocyte Maturation and Fertilization
J. Biol. Chem. 2002 277: 2763-2772. First Published on October 30, 2001; 10.1074/jbc.M108839200 [Abstract] [Full Text] [PDF]  

Toshihiro Mochizuki, Akio Asai, Nobuhito Saito, Sakae Tanaka, Hideki Katagiri, Tomoichiro Asano, Makoto Nakane, Akira Tamura, Yoshiyuki Kuchino, Chifumi Kitanaka, and Takaaki Kirino
Akt Protein Kinase Inhibits Non-apoptotic Programmed Cell Death Induced by Ceramide
J. Biol. Chem. 2002 277: 2790-2797. First Published on November 12, 2001; 10.1074/jbc.M106361200 [Abstract] [Full Text] [PDF]  

Philip J. Young, Patricia M. Day, Jianhua Zhou, Elliot J. Androphy, Glenn E. Morris, and Christian L. Lorson
A Direct Interaction between the Survival Motor Neuron Protein and p53 and Its Relationship to Spinal Muscular Atrophy
J. Biol. Chem. 2002 277: 2852-2859. First Published on November 9, 2001; 10.1074/jbc.M108769200 [Abstract] [Full Text] [PDF]  

Naoki Matsuo, Mikio Hoshino, Masato Yoshizawa, and Yo-ichi Nabeshima
Characterization of STEF, a Guanine Nucleotide Exchange Factor for Rac1, Required for Neurite Growth
J. Biol. Chem. 2002 277: 2860-2868. First Published on November 13, 2001; 10.1074/jbc.M106186200 [Abstract] [Full Text] [PDF]  

James F. Sinclair and Alison D. O'Brien
Cell Surface-localized Nucleolin Is a Eukaryotic Receptor for the Adhesin Intimin-gamma of Enterohemorrhagic Escherichia coli O157:H7
J. Biol. Chem. 2002 277: 2876-2885. First Published on November 9, 2001; 10.1074/jbc.M110230200 [Abstract] [Full Text] [PDF]  

Additions and Corrections:

Hiroshi Ueda, Rika Morishita, Hiroshi Itoh, Shuh Narumiya, Katsuhiko Mikoshiba, Kanefusa Kato, and Tomiko Asano
Galpha 11 induces caspase-mediated proteolytic activation of Rho-associated kinase, ROCK-I, in HeLa cells.
J. Biol. Chem. 2002 277: 3060. [Full Text] [PDF]  

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