JBC -- Table of Contents (Oct 18 2002, 277, (42))

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Robert D. Simoni, Robert L. Hill, and Martha Vaughan: Purification of Progestin(s): Oskar Wintersteiner
CRYSTALLINE PROGESTIN (Oskar Wintersteiner and Willard M. Allen J. Biol. Chem. 107, 321-336)
J. Biol. Chem. 2002 277: e30. [Full Text]

Accelerated Publications:

Harald Steiner, Edith Winkler, Dieter Edbauer, Stefan Prokop, Gabriele Basset, Aya Yamasaki, Marcus Kostka, and Christian Haass: PEN-2 Is an Integral Component of the $gamma$ -Secretase Complex Required for Coordinated Expression of Presenilin and Nicastrin
J. Biol. Chem. 2002 277: 39062-39065. First Published on August 26, 2002; doi:10.1074/jbc.C200469200 [Abstract] [Full Text] [PDF]

Ernest Kun, Eva Kirsten, and Charles P. Ordahl: Coenzymatic Activity of Randomly Broken or Intact Double-stranded DNAs in Auto and Histone H₁ Trans-poly(ADP-ribosylation), Catalyzed by Poly(ADP-ribose) Polymerase (PARP I)
J. Biol. Chem. 2002 277: 39066-39069. First Published on August 29, 2002; doi:10.1074/jbc.C200410200 [Abstract] [Full Text] [PDF]

Makoto Ashiuchi, Eriko Kuwana, Takashi Yamamoto, Kazuya Komatsu, Kenji Soda, and Haruo Misono: Glutamate Racemase Is an Endogenous DNA Gyrase Inhibitor
J. Biol. Chem. 2002 277: 39070-39073. First Published on September 3, 2002; doi:10.1074/jbc.C200253200 [Abstract] [Full Text] [PDF]

DNA: Replication, Repair, and Recombination:

Alexandre A. Vetcher, Marek Napierala, Ravi R. Iyer, Paul D. Chastain, Jack D. Griffith, and Robert D. Wells: Sticky DNA, a Long GAA·GAA·TTC Triplex That Is Formed Intramolecularly, in the Sequence of Intron 1 of the Frataxin Gene
J. Biol. Chem. 2002 277: 39217-39227. First Published on August 2, 2002; doi:10.1074/jbc.M205209200 [Abstract] [Full Text] [PDF]

Alexandre A. Vetcher, Marek Napierala, and Robert D. Wells: Sticky DNA: Effect of the Polypurine·Polypyrimidine Sequence
J. Biol. Chem. 2002 277: 39228-39234. First Published on August 2, 2002; doi:10.1074/jbc.M205210200 [Abstract] [Full Text] [PDF]

Aimee L. Eggler, Ross B. Inman, and Michael M. Cox: The Rad51-dependent Pairing of Long DNA Substrates Is Stabilized by Replication Protein A
J. Biol. Chem. 2002 277: 39280-39288. First Published on August 6, 2002; doi:10.1074/jbc.M204328200 [Abstract] [Full Text] [PDF]

Kevin M. Carr and Jon M. Kaguni: Escherichia coli DnaA Protein Loads a Single DnaB Helicase at a DnaA Box Hairpin
J. Biol. Chem. 2002 277: 39815-39822. First Published on August 2, 2002; doi:10.1074/jbc.M205031200 [Abstract] [Full Text] [PDF]

Bodil Kavli, Ottar Sundheim, Mansour Akbari, Marit Otterlei, Hilde Nilsen, Frank Skorpen, Per Arne Aas, Lars Hagen, Hans E. Krokan, and Geir Slupphaug: hUNG2 Is the Major Repair Enzyme for Removal of Uracil from U:A Matches, U:G Mismatches, and U in Single-stranded DNA, with hSMUG1 as a Broad Specificity Backup
J. Biol. Chem. 2002 277: 39926-39936. First Published on August 2, 2002; doi:10.1074/jbc.M207107200 [Abstract] [Full Text] [PDF]

Lumir Krejci, Binwei Song, Wendy Bussen, Rodney Rothstein, Uffe H. Mortensen, and Patrick Sung: Interaction with Rad51 Is Indispensable for Recombination Mediator Function of Rad52
J. Biol. Chem. 2002 277: 40132-40141. First Published on August 8, 2002; doi:10.1074/jbc.M206511200 [Abstract] [Full Text] [PDF]

Genes: Structure and Regulation:

Chiharu Uchida, Toshiaki Oda, Tsuyoshi Sugiyama, Sunao Otani, Masatoshi Kitagawa, and Arata Ichiyama: The Role of Sp1 and AP-2 in Basal and Protein Kinase A-induced Expression of Mitochondrial Serine:Pyruvate Aminotransferase in Hepatocytes
J. Biol. Chem. 2002 277: 39082-39092. First Published on August 6, 2002; doi:10.1074/jbc.M201380200 [Abstract] [Full Text] [PDF]

Chi-Ming Chiu, Yeou-Guang Tsay, Ching-Jin Chang, and Sheng-Chung Lee: Nopp140 Is a Mediator of the Protein Kinase A Signaling Pathway That Activates the Acute Phase Response $alpha$ ₁-Acid Glycoprotein Gene
J. Biol. Chem. 2002 277: 39102-39111. First Published on August 7, 2002; doi:10.1074/jbc.M205915200 [Abstract] [Full Text] [PDF]

Florence Gizard, Bernard Lavallée, Fredérique DeWitte, Elisabeth Teissier, Bart Staels, and Dean W. Hum: The Transcriptional Regulating Protein of 132 kDa (TReP-132) Enhances P450scc Gene Transcription through Interaction with Steroidogenic Factor-1 in Human Adrenal Cells
J. Biol. Chem. 2002 277: 39144-39155. First Published on July 5, 2002; doi:10.1074/jbc.M205786200 [Abstract] [Full Text] [PDF]

Anjali Pawar, Jinghua Xu, Erik Jerks, David J. Mangelsdorf, and Donald B. Jump: Fatty Acid Regulation of Liver X Receptors (LXR) and Peroxisome Proliferator-activated Receptor $alpha$ (PPAR $alpha$ ) in HEK293 Cells
J. Biol. Chem. 2002 277: 39243-39250. First Published on August 2, 2002; doi:10.1074/jbc.M206170200 [Abstract] [Full Text] [PDF]

Ghil Jona, Liane L. Livi, and Opher Gileadi: Mutations in the RING Domain of TFB3, a Subunit of Yeast Transcription Factor IIH, Reveal a Role in Cell Cycle Progression
J. Biol. Chem. 2002 277: 39409-39416. First Published on August 9, 2002; doi:10.1074/jbc.M202733200 [Abstract] [Full Text] [PDF]

Jun Li, Daron C. Barnard, and James G. Patton: A Unique Glutamic Acid-Lysine (EK) Domain Acts as a Splicing Inhibitor
J. Biol. Chem. 2002 277: 39485-39492. First Published on August 14, 2002; doi:10.1074/jbc.M201784200 [Abstract] [Full Text] [PDF]

Jochen A. Stadler and Rudolf J. Schweyen: The Yeast Iron Regulon Is Induced upon Cobalt Stress and Crucial for Cobalt Tolerance
J. Biol. Chem. 2002 277: 39649-39654. First Published on August 9, 2002; doi:10.1074/jbc.M203924200 [Abstract] [Full Text] [PDF]

Anders Hackzell, Hidetaka Uramoto, Hiroto Izumi, Kimitoshi Kohno, and Keiko Funa: p73 Independent of c-Myc Represses Transcription of Platelet-derived Growth Factor $beta$ -Receptor through Interaction with NF-Y
J. Biol. Chem. 2002 277: 39769-39776. First Published on August 6, 2002; doi:10.1074/jbc.M204483200 [Abstract] [Full Text] [PDF]

Tiina-Liisa Räsänen, Leena Alhonen, Riitta Sinervirta, Tuomo Keinänen, Karl-Heinz Herzig, Suvikki Suppola, Alex R. Khomutov, Jouko Vepsäläinen, and Juhani Jänne: A Polyamine Analogue Prevents Acute Pancreatitis and Restores Early Liver Regeneration in Transgenic Rats with Activated Polyamine Catabolism
J. Biol. Chem. 2002 277: 39867-39872. First Published on August 13, 2002; doi:10.1074/jbc.M205967200 [Abstract] [Full Text] [PDF]

Jinhua Li, Sung Wook Park, Horace H. Loh, and Li-Na Wei: Induction of the Mouse $kappa$ -Opioid Receptor Gene by Retinoic Acid in P19 Cells
J. Biol. Chem. 2002 277: 39967-39972. First Published on August 8, 2002; doi:10.1074/jbc.M200840200 [Abstract] [Full Text] [PDF]

Sergiy Lopato, Christina Forstner, Maria Kalyna, Julia Hilscher, Ulrike Langhammer, Korakod Indrapichate, Zdravko J. Lorkovi $c'$ , and Andrea Barta: Network of Interactions of a Novel Plant-specific Arg/Ser-rich Protein, atRSZ33, with atSC35-like Splicing Factors
J. Biol. Chem. 2002 277: 39989-39998. First Published on August 9, 2002; doi:10.1074/jbc.M206455200 [Abstract] [Full Text] [PDF]

Scott R. Eberhardy and Peggy J. Farnham: Myc Recruits P-TEFb to Mediate the Final Step in the Transcriptional Activation of the cad Promoter
J. Biol. Chem. 2002 277: 40156-40162. First Published on August 9, 2002; doi:10.1074/jbc.M207441200 [Abstract] [Full Text] [PDF]

RNA: Structure, Metabolism, and Catalysis:

Naoki Shigi, Tsutomu Suzuki, Masatada Tamakoshi, Tairo Oshima, and Kimitsuna Watanabe: Conserved Bases in the T $Psi$ C Loop of tRNA Are Determinants for Thermophile-specific 2-Thiouridylation at Position 54
J. Biol. Chem. 2002 277: 39128-39135. First Published on August 12, 2002; doi:10.1074/jbc.M207323200 [Abstract] [Full Text] [PDF]

Chee-Gun Lee: RH70, a Bidirectional RNA Helicase, Co-purifies with U1snRNP
J. Biol. Chem. 2002 277: 39679-39683. First Published on August 21, 2002; doi:10.1074/jbc.C200337200 [Abstract] [Full Text] [PDF]

Protein Synthesis, Post-Translation Modification, and Degradation:

R. Senthilkumar, Raghothama Chaerkady, and K. Krishna Sharma: Identification and Properties of Anti-chaperone-like Peptides Derived from Oxidized Bovine Lens $beta$ _L-Crystallins
J. Biol. Chem. 2002 277: 39136-39143. First Published on August 9, 2002; doi:10.1074/jbc.M204684200 [Abstract] [Full Text] [PDF]

Margreet A. Wolfert, Thomas F. Murray, Geert-Jan Boons, and James N. Moore: The Origin of the Synergistic Effect of Muramyl Dipeptide with Endotoxin and Peptidoglycan
J. Biol. Chem. 2002 277: 39179-39186. First Published on July 31, 2002; doi:10.1074/jbc.M204885200 [Abstract] [Full Text] [PDF]

Bettina Sarg, Elisavet Koutzamani, Wilfried Helliger, Ingemar Rundquist, and Herbert H. Lindner: Postsynthetic Trimethylation of Histone H4 at Lysine 20 in Mammalian Tissues Is Associated with Aging
J. Biol. Chem. 2002 277: 39195-39201. First Published on August 1, 2002; doi:10.1074/jbc.M205166200 [Abstract] [Full Text] [PDF]

Alison Spiers, Heather K. Lamb, Simon Cocklin, Kerry A. Wheeler, Jo Budworth, Anna L. Dodds, Mark J. Pallen, Duncan J. Maskell, Ian G. Charles, and Alastair R. Hawkins: PDZ Domains Facilitate Binding of High Temperature Requirement Protease A (HtrA) and Tail-specific Protease (Tsp) to Heterologous Substrates through Recognition of the Small Stable RNA A (ssrA)-encoded Peptide
J. Biol. Chem. 2002 277: 39443-39449. First Published on August 12, 2002; doi:10.1074/jbc.M202790200 [Abstract] [Full Text] [PDF]

Hiroto Komano, Hirohisa Shiraishi, Yuuki Kawamura, Xiaorei Sai, Ryo Suzuki, Lutgarde Serneels, Masashi Kawaichi, Toshio Kitamura, and Katsuhiko Yanagisawa: A New Functional Screening System for Identification of Regulators for the Generation of Amyloid $beta$ -Protein
J. Biol. Chem. 2002 277: 39627-39633. First Published on August 2, 2002; doi:10.1074/jbc.M205255200 [Abstract] [Full Text] [PDF]

Véronique Bailly, Zhiwei Zhang, Werner Meier, Richard Cate, Michele Sanicola, and Joseph V. Bonventre: Shedding of Kidney Injury Molecule-1, a Putative Adhesion Protein Involved in Renal Regeneration
J. Biol. Chem. 2002 277: 39739-39748. First Published on July 23, 2002; doi:10.1074/jbc.M200562200 [Abstract] [Full Text] [PDF]

Andrea D. Basso, David B. Solit, Gabriela Chiosis, Banabihari Giri, Philip Tsichlis, and Neal Rosen: Akt Forms an Intracellular Complex with Heat Shock Protein 90 (Hsp90) and Cdc37 and Is Destabilized by Inhibitors of Hsp90 Function
J. Biol. Chem. 2002 277: 39858-39866. First Published on August 9, 2002; doi:10.1074/jbc.M206322200 [Abstract] [Full Text] [PDF]

Mina I. Zhou, Hongmei Wang, Jonathan J. Ross, Igor Kuzmin, Chengen Xu, and Herbert T. Cohen: The von Hippel-Lindau Tumor Suppressor Stabilizes Novel Plant Homeodomain Protein Jade-1
J. Biol. Chem. 2002 277: 39887-39898. First Published on August 6, 2002; doi:10.1074/jbc.M205040200 [Abstract] [Full Text] [PDF]

Prasad Rallabhandi, Keiko Hashimoto, Yin-Yuan Mo, William T. Beck, Prasun K. Moitra, and Peter D'Arpa: Sumoylation of Topoisomerase I Is Involved in Its Partitioning between Nucleoli and Nucleoplasm and Its Clearing from Nucleoli in Response to Camptothecin
J. Biol. Chem. 2002 277: 40020-40026. First Published on July 30, 2002; doi:10.1074/jbc.M200388200 [Abstract] [Full Text] [PDF]

Denise A. Chan, Patrick D. Sutphin, Nicholas C. Denko, and Amato J. Giaccia: Role of Prolyl Hydroxylation in Oncogenically Stabilized Hypoxia-inducible Factor-1 $alpha$
J. Biol. Chem. 2002 277: 40112-40117. First Published on August 16, 2002; doi:10.1074/jbc.M206922200 [Abstract] [Full Text] [PDF]

Genomics, Proteomics, and Bioinformatics:

Myriam Bernaudin, Yang Tang, Melinda Reilly, Edwige Petit, and Frank R. Sharp: Brain Genomic Response following Hypoxia and Re-oxygenation in the Neonatal Rat. IDENTIFICATION OF GENES THAT MIGHT CONTRIBUTE TO HYPOXIA-INDUCED ISCHEMIC TOLERANCE
J. Biol. Chem. 2002 277: 39728-39738. First Published on July 26, 2002; doi:10.1074/jbc.M204619200 [Abstract] [Full Text] [PDF]

Julius Nyalwidhe, Stefan Baumeister, Alan R. Hibbs, Sallah Tawill, Janni Papakrivos, Uwe Völker, and Klaus Lingelbach: A Nonpermeant Biotin Derivative Gains Access to the Parasitophorous Vacuole in Plasmodium falciparum-infected Erythrocytes Permeabilized with Streptolysin O
J. Biol. Chem. 2002 277: 40005-40011. First Published on August 16, 2002; doi:10.1074/jbc.M207077200 [Abstract] [Full Text] [PDF]

Protein Structure and Folding:

Heather L. Greenstone, Fabio Santoro, Paolo Lusso, and Edward A. Berger: Human Herpesvirus 6 and Measles Virus Employ Distinct CD46 Domains for Receptor Function
J. Biol. Chem. 2002 277: 39112-39118. First Published on August 8, 2002; doi:10.1074/jbc.M206488200 [Abstract] [Full Text] [PDF]

Kristin Carveth, Teresa Buck, Victoria Anthony, and William R. Skach: Cooperativity and Flexibility of Cystic Fibrosis Transmembrane Conductance Regulator Transmembrane Segments Participate in Membrane Localization of a Charged Residue
J. Biol. Chem. 2002 277: 39507-39514. First Published on August 18, 2002; doi:10.1074/jbc.M205759200 [Abstract] [Full Text] [PDF]

Sam J. P. Gobin, Paula Biesta, Jurriaan E. M. de Steenwinkel, Gert Datema, and Peter J. Van den Elsen: HLA-G Transactivation by cAMP-response Element-binding Protein (CREB). AN ALTERNATIVE TRANSACTIVATION PATHWAY TO THE CONSERVED MAJOR HISTOCOMPATIBILITY COMPLEX (MHC) CLASS I REGULATORY ROUTES
J. Biol. Chem. 2002 277: 39525-39531. First Published on August 14, 2002; doi:10.1074/jbc.M112273200 [Abstract] [Full Text] [PDF]

Stephen Poon, Mark S. Rybchyn, Simon B. Easterbrook-Smith, John A. Carver, Greg J. Pankhurst, and Mark R. Wilson: Mildly Acidic pH Activates the Extracellular Molecular Chaperone Clusterin
J. Biol. Chem. 2002 277: 39532-39540. First Published on August 9, 2002; doi:10.1074/jbc.M204855200 [Abstract] [Full Text] [PDF]

Adriana A. Paulucci, Leslie Hicks, Alessandra Machado, M. Terêsa M. Miranda, Cyril M. Kay, and Chuck S. Farah: Specific Sequences Determine the Stability and Cooperativity of Folding of the C-terminal Half of Tropomyosin
J. Biol. Chem. 2002 277: 39574-39584. First Published on August 7, 2002; doi:10.1074/jbc.M204749200 [Abstract] [Full Text] [PDF]

Daniel R. Gallie, David Fortner, Jamy Peng, and David Puthoff: ATP-dependent Hexameric Assembly of the Heat Shock Protein Hsp101 Involves Multiple Interaction Domains and a Functional C-proximal Nucleotide-binding Domain
J. Biol. Chem. 2002 277: 39617-39626. First Published on July 31, 2002; doi:10.1074/jbc.M204998200 [Abstract] [Full Text] [PDF]

Isabelle H. Barrette-Ng, Kenneth K.-S. Ng, Brian L. Mark, Danny van Aken, Maia M. Cherney, Craig Garen, Yuliya Kolodenko, Alexander E. Gorbalenya, Eric J. Snijder, and Michael N. G. James: Structure of Arterivirus nsp4. THE SMALLEST CHYMOTRYPSIN-LIKE PROTEINASE WITH AN $alpha$ / $beta$ C-TERMINAL EXTENSION AND ALTERNATE CONFORMATIONS OF THE OXYANION HOLE
J. Biol. Chem. 2002 277: 39960-39966. First Published on August 5, 2002; doi:10.1074/jbc.M206978200 [Abstract] [Full Text] [PDF]

Mitsunori Fukuda: Synaptotagmin-like Protein (Slp) Homology Domain 1 of Slac2-a/Melanophilin Is a Critical Determinant of GTP-dependent Specific Binding to Rab27A
J. Biol. Chem. 2002 277: 40118-40124. First Published on August 19, 2002; doi:10.1074/jbc.M205765200 [Abstract] [Full Text] [PDF]

Enzyme Catalysis and Regulation:

Brice Korkmaz, Sylvie Attucci, Eric Hazouard, Martine Ferrandière, Marie Lise Jourdan, Michèle Brillard-Bourdet, Luiz Juliano, and Francis Gauthier: Discriminating between the Activities of Human Neutrophil Elastase and Proteinase 3 Using Serpin-derived Fluorogenic Substrates
J. Biol. Chem. 2002 277: 39074-39081. First Published on July 11, 2002; doi:10.1074/jbc.M202918200 [Abstract] [Full Text] [PDF]

Ye Qi Liu, Thomas L. Jetton, and Jack L. Leahy: $beta$ -Cell Adaptation to Insulin Resistance. INCREASED PYRUVATE CARBOXYLASE AND MALATE-PYRUVATE SHUTTLE ACTIVITY IN ISLETS OF NONDIABETIC ZUCKER FATTY RATS
J. Biol. Chem. 2002 277: 39163-39168. First Published on July 29, 2002; doi:10.1074/jbc.M207157200 [Abstract] [Full Text] [PDF]

Stéphane Marchal and Guy Branlant: Characterization of the Amino Acids Involved in Substrate Specificity of Nonphosphorylating Glyceraldehyde-3-Phosphate Dehydrogenase from Streptococcus mutans
J. Biol. Chem. 2002 277: 39235-39242. First Published on August 5, 2002; doi:10.1074/jbc.M205633200 [Abstract] [Full Text] [PDF]

Nandini Rudra-Ganguly, Srinivasa T. Reddy, Paavo Korge, and Harvey R. Herschman: Diesel Exhaust Particle Extracts and Associated Polycyclic Aromatic Hydrocarbons Inhibit Cox-2-dependent Prostaglandin Synthesis in Murine Macrophages and Fibroblasts
J. Biol. Chem. 2002 277: 39259-39265. First Published on August 5, 2002; doi:10.1074/jbc.M110215200 [Abstract] [Full Text] [PDF]

Gregg R. Tulik, Sundari Chodavarapu, Rick Edgar, Lenore Giannunzio, Amie Langland, Billie Schultz, and Joe D. Beckmann: Inhibition of Bovine Phenol Sulfotransferase (bSULT1A1) by CoA Thioesters. EVIDENCE FOR POSITIVE COOPERATIVITY AND INHIBITION BY INTERACTION WITH BOTH THE NUCLEOTIDE AND PHENOL BINDING SITES
J. Biol. Chem. 2002 277: 39296-39303. First Published on August 6, 2002; doi:10.1074/jbc.M206017200 [Abstract] [Full Text] [PDF]

Akira Tokumura, Eiji Majima, Yuko Kariya, Kyoko Tominaga, Kentaro Kogure, Katsuhiko Yasuda, and Kenji Fukuzawa: Identification of Human Plasma Lysophospholipase D, a Lysophosphatidic Acid-producing Enzyme, as Autotaxin, a Multifunctional Phosphodiesterase
J. Biol. Chem. 2002 277: 39436-39442. First Published on August 9, 2002; doi:10.1074/jbc.M205623200 [Abstract] [Full Text] [PDF]

Tai Man Louie, Haw Yang, Pallop Karnchanaphanurach, X. Sunney Xie, and Luying Xun: FAD Is a Preferred Substrate and an Inhibitor of Escherichia coli General NAD(P)H:Flavin Oxidoreductase
J. Biol. Chem. 2002 277: 39450-39455. First Published on August 12, 2002; doi:10.1074/jbc.M206339200 [Abstract] [Full Text] [PDF]

Rong Zhao and Arne Holmgren: A Novel Antioxidant Mechanism of Ebselen Involving Ebselen Diselenide, a Substrate of Mammalian Thioredoxin and Thioredoxin Reductase
J. Biol. Chem. 2002 277: 39456-39462. First Published on August 12, 2002; doi:10.1074/jbc.M206452200 [Abstract] [Full Text] [PDF]

Shigeru Miyata, Junzaburo Minami, Eiji Tamai, Osamu Matsushita, Seiko Shimamoto, and Akinobu Okabe: Clostridium perfringens $epsilon$ -Toxin Forms a Heptameric Pore within the Detergent-insoluble Microdomains of Madin-Darby Canine Kidney Cells and Rat Synaptosomes
J. Biol. Chem. 2002 277: 39463-39468. First Published on August 12, 2002; doi:10.1074/jbc.M206731200 [Abstract] [Full Text] [PDF]

Gregory A. Grant, Zhiqin Hu, and Xiao Lan Xu: Cofactor Binding to Escherichia coli D-3-Phosphoglycerate Dehydrogenase Induces Multiple Conformations Which Alter Effector Binding
J. Biol. Chem. 2002 277: 39548-39553. First Published on August 14, 2002; doi:10.1074/jbc.M208019200 [Abstract] [Full Text] [PDF]

James B. Thoden, Xinyi Huang, Frank M. Raushel, and Hazel M. Holden: Carbamoyl-phosphate Synthetase. CREATION OF AN ESCAPE ROUTE FOR AMMONIA
J. Biol. Chem. 2002 277: 39722-39727. First Published on July 18, 2002; doi:10.1074/jbc.M206915200 [Abstract] [Full Text] [PDF]

Sarah Gallois-Montbrun, Benoit Schneider, Yuxing Chen, Véronique Giacomoni-Fernandes, Laurence Mulard, Solange Morera, Joël Janin, Dominique Deville-Bonne, and Michel Veron: Improving Nucleoside Diphosphate Kinase for Antiviral Nucleotide Analogs Activation
J. Biol. Chem. 2002 277: 39953-39959. First Published on August 8, 2002; doi:10.1074/jbc.M206360200 [Abstract] [Full Text] [PDF]

Anne E. Sarver and Ching C. Wang: The Adenine Phosphoribosyltransferase from Giardia lamblia Has a Unique Reaction Mechanism and Unusual Substrate Binding Properties
J. Biol. Chem. 2002 277: 39973-39980. First Published on August 8, 2002; doi:10.1074/jbc.M205595200 [Abstract] [Full Text] [PDF]

Wuxian Shi, Anne E. Sarver, Ching C. Wang, Kelly S. E. Tanaka, Steven C. Almo, and Vern L. Schramm: Closed Site Complexes of Adenine Phosphoribosyltransferase from Giardia lamblia Reveal a Mechanism of Ribosyl Migration
J. Biol. Chem. 2002 277: 39981-39988. First Published on August 8, 2002; doi:10.1074/jbc.M205596200 [Abstract] [Full Text] [PDF]

Moon Suk Kim, Min Ji Baek, Mi Hee Lee, Ji Won Park, So Young Lee, Kenneth Söderhäll, and Bok Luel Lee: A New Easter-type Serine Protease Cleaves a Masquerade-like Protein during Prophenoloxidase Activation in Holotrichia diomphalia Larvae
J. Biol. Chem. 2002 277: 39999-40004. First Published on August 15, 2002; doi:10.1074/jbc.M205508200 [Abstract] [Full Text] [PDF]

Andreas Becker and Wolfgang Kabsch: X-ray Structure of Pyruvate Formate-Lyase in Complex with Pyruvate and CoA. HOW THE ENZYME USES THE CYS-418 THIYL RADICAL FOR PYRUVATE CLEAVAGE
J. Biol. Chem. 2002 277: 40036-40042. First Published on August 5, 2002; doi:10.1074/jbc.M205821200 [Abstract] [Full Text] [PDF]

Spencer J. Williams, Brian L. Mark, David J. Vocadlo, Michael N. G. James, and Stephen G. Withers: Aspartate 313 in the Streptomyces plicatus Hexosaminidase Plays a Critical Role in Substrate-assisted Catalysis by Orienting the 2-Acetamido Group and Stabilizing the Transition State
J. Biol. Chem. 2002 277: 40055-40065. First Published on August 8, 2002; doi:10.1074/jbc.M206481200 [Abstract] [Full Text] [PDF]

Tsukasa Osaki, Nozomu Okino, Fuminori Tokunaga, Sadaaki Iwanaga, and Shun-ichiro Kawabata: Proline-rich Cell Surface Antigens of Horseshoe Crab Hemocytes Are Substrates for Protein Cross-linking with a Clotting Protein Coagulin
J. Biol. Chem. 2002 277: 40084-40090. First Published on August 19, 2002; doi:10.1074/jbc.M206773200 [Abstract] [Full Text] [PDF]

Metabolism and Bioenergetics:

Mary Dienhart, Kathy Pfeiffer, Hermann Schägger, and Rosemary A. Stuart: Formation of the Yeast F₁F₀-ATP Synthase Dimeric Complex Does Not Require the ATPase Inhibitor Protein, Inh1
J. Biol. Chem. 2002 277: 39289-39295. First Published on August 6, 2002; doi:10.1074/jbc.M205720200 [Abstract] [Full Text] [PDF]

Toshio Iwasaki, Asako Kounosu, Miho Aoshima, Daijiro Ohmori, Takeo Imai, Akio Urushiyama, Nathaniel J. Cosper, and Robert A. Scott: Novel [2Fe-2S]-type Redox Center C in SdhC of Archaeal Respiratory Complex II from Sulfolobus tokodaii Strain 7
J. Biol. Chem. 2002 277: 39642-39648. First Published on August 6, 2002; doi:10.1074/jbc.M207312200 [Abstract] [Full Text] [PDF]

Priya Rangaraj and Paul W. Ludden: Accumulation of ⁹⁹Mo-containing Iron-Molybdenum Cofactor Precursors of Nitrogenase on NifNE, NifH, and NifX of Azotobacter vinelandii
J. Biol. Chem. 2002 277: 40106-40111. First Published on August 9, 2002; doi:10.1074/jbc.M204581200 [Abstract] [Full Text] [PDF]

Glycobiology and Extracellular Matrices:

Linlin Ma, William A. Rudert, Jo Harnaha, Marietta Wright, Jennifer Machen, Robert Lakomy, Shiguang Qian, Lina Lu, Paul D. Robbins, Massimo Trucco, and Nick Giannoukakis: Immunosuppressive Effects of Glucosamine
J. Biol. Chem. 2002 277: 39343-39349. First Published on August 9, 2002; doi:10.1074/jbc.M204924200 [Abstract] [Full Text] [PDF]

Ningguo Gao and Mark A. Lehrman: Coupling of the Dolichol-P-P-Oligosaccharide Pathway to Translation by Perturbation-sensitive Regulation of the Initiating Enzyme, GlcNAc-1-P Transferase
J. Biol. Chem. 2002 277: 39425-39435. First Published on August 9, 2002; doi:10.1074/jbc.M205195200 [Abstract] [Full Text] [PDF]

Anne Leppänen, Leena Penttilä, Ossi Renkonen, Rodger P. McEver, and Richard D. Cummings: Glycosulfopeptides with O-Glycans Containing Sialylated and Polyfucosylated Polylactosamine Bind with Low Affinity to P-selectin
J. Biol. Chem. 2002 277: 39749-39759. First Published on July 26, 2002; doi:10.1074/jbc.M206281200 [Abstract] [Full Text] [PDF]

Qinlong Zheng, Irma Van Die, and Richard D. Cummings: Molecular Cloning and Characterization of a Novel $alpha$ 1,2-Fucosyltransferase (CE2FT-1) from Caenorhabditis elegans
J. Biol. Chem. 2002 277: 39823-39832. First Published on August 5, 2002; doi:10.1074/jbc.M207487200 [Abstract] [Full Text] [PDF]

Revital Shamri, Valentin Grabovsky, Sara W. Feigelson, Oren Dwir, Yvette van Kooyk, and Ronen Alon: Chemokine Stimulation of Lymphocyte $alpha$ ₄ Integrin Avidity but Not of Leukocyte Function-associated Antigen-1 Avidity to Endothelial Ligands under Shear Flow Requires Cholesterol Membrane Rafts
J. Biol. Chem. 2002 277: 40027-40035. First Published on August 5, 2002; doi:10.1074/jbc.M206806200 [Abstract] [Full Text] [PDF]

Dorin-Bogdan Borza, Olga Bondar, Parvin Todd, Munirathinam Sundaramoorthy, Yoshikazu Sado, Yoshifumi Ninomiya, and Billy G. Hudson: Quaternary Organization of the Goodpasture Autoantigen, the $alpha$ 3(IV) Collagen Chain. SEQUESTRATION OF TWO CRYPTIC AUTOEPITOPES BY INTRAPROTOMER INTERACTIONS WITH THE $alpha$ 4 AND $alpha$ 5 NC1 DOMAINS
J. Biol. Chem. 2002 277: 40075-40083. First Published on August 21, 2002; doi:10.1074/jbc.M207769200 [Abstract] [Full Text] [PDF]

Lipids and Lipoproteins:

Hui-hua Li, Douglas S. Lyles, Wei Pan, Eric Alexander, Michael J. Thomas, and Mary G. Sorci-Thomas: ApoA-I Structure on Discs and Spheres. VARIABLE HELIX REGISTRY AND CONFORMATIONAL STATES
J. Biol. Chem. 2002 277: 39093-39101. First Published on August 6, 2002; doi:10.1074/jbc.M206770200 [Abstract] [Full Text] [PDF]

Isabelle Lefrère, Pierre de Coppet, Jean-Claude Camelin, Soazig Le Lay, Nathalie Mercier, Nabil Elshourbagy, Antoine Bril, Isabelle Berrebi-Bertrand, Bruno Fève, and Stéphane Krief: Neuropeptide AF and FF Modulation of Adipocyte Metabolism. PRIMARY INSIGHTS FROM FUNCTIONAL GENOMICS AND EFFECTS ON $beta$ -ADRENERGIC RESPONSIVENESS
J. Biol. Chem. 2002 277: 39169-39178. First Published on July 30, 2002; doi:10.1074/jbc.M205084200 [Abstract] [Full Text] [PDF]

Stacey E. Panagotopulos, Scott R. Witting, Erica M. Horace, David Y. Hui, J. Nicholas Maiorano, and W. Sean Davidson: The Role of Apolipoprotein A-I Helix 10 in Apolipoprotein-mediated Cholesterol Efflux via the ATP-binding Cassette Transporter ABCA1
J. Biol. Chem. 2002 277: 39477-39484. First Published on August 13, 2002; doi:10.1074/jbc.M207005200 [Abstract] [Full Text] [PDF]

Karnail Singh, Olcay A. Batuman, Hassan O. Akman, Mamdouh H. Kedees, Varsha Vakil, and M. Mahmood Hussain: Differential, Tissue-specific, Transcriptional Regulation of Apolipoprotein B Secretion by Transforming Growth Factor $beta$
J. Biol. Chem. 2002 277: 39515-39524. First Published on August 12, 2002; doi:10.1074/jbc.M205513200 [Abstract] [Full Text] [PDF]

Guoqing Cao, Thomas P. Beyer, Xiao Ping Yang, Robert J. Schmidt, Youyan Zhang, William R. Bensch, Raymond F. Kauffman, Hong Gao, Timothy P. Ryan, Yu Liang, Patrick I. Eacho, and Xian-Cheng Jiang: Phospholipid Transfer Protein Is Regulated by Liver X Receptors in Vivo
J. Biol. Chem. 2002 277: 39561-39565. First Published on August 9, 2002; doi:10.1074/jbc.M207187200 [Abstract] [Full Text] [PDF]

Junko Ishii, Hideki Adachi, Junken Aoki, Hiroyuki Koizumi, Susumu Tomita, Toshiharu Suzuki, Masafumi Tsujimoto, Keizo Inoue, and Hiroyuki Arai: SREC-II, a New Member of the Scavenger Receptor Type F Family, Trans-interacts with SREC-I through Its Extracellular Domain
J. Biol. Chem. 2002 277: 39696-39702. First Published on August 1, 2002; doi:10.1074/jbc.M206140200 [Abstract] [Full Text] [PDF]

Membrane Transport, Structure, Function, and Biogenesis:

Colin W. MacDiarmid, Mark A. Milanick, and David J. Eide: Biochemical Properties of Vacuolar Zinc Transport Systems of Saccharomyces cerevisiae
J. Biol. Chem. 2002 277: 39187-39194. First Published on August 2, 2002; doi:10.1074/jbc.M205052200 [Abstract] [Full Text] [PDF]

Heinrich Jung, Marion Buchholz, Jürgen Clausen, Monika Nietschke, Anne Revermann, Roland Schmid, and Kirsten Jung: CaiT of Escherichia coli, a New Transporter Catalyzing L-Carnitine/ $gamma$ -Butyrobetaine Exchange
J. Biol. Chem. 2002 277: 39251-39258. First Published on August 5, 2002; doi:10.1074/jbc.M206319200 [Abstract] [Full Text] [PDF]

Xiaobin Han, Andrea Budreau Patters, and Russell W. Chesney: Transcriptional Repression of Taurine Transporter Gene (TauT) by p53 in Renal Cells
J. Biol. Chem. 2002 277: 39266-39273. First Published on August 5, 2002; doi:10.1074/jbc.M205939200 [Abstract] [Full Text] [PDF]

Nicoletta Kahya, Douwe A. Wiersma, Bert Poolman, and Dick Hoekstra: Spatial Organization of Bacteriorhodopsin in Model Membranes. LIGHT-INDUCED MOBILITY CHANGES
J. Biol. Chem. 2002 277: 39304-39311. First Published on August 7, 2002; doi:10.1074/jbc.M202635200 [Abstract] [Full Text] [PDF]

Maurice Chelli and Marc Alizon: Rescue of HIV-1 Receptor Function through Cooperation between Different Forms of the CCR5 Chemokine Receptor
J. Biol. Chem. 2002 277: 39388-39396. First Published on August 1, 2002; doi:10.1074/jbc.M205394200 [Abstract] [Full Text] [PDF]

Nikhil deSouza, Steven Reiken, Karol Ondrias, Yi-ming Yang, Scot Matkovich, and Andrew R. Marks: Protein Kinase A and Two Phosphatases Are Components of the Inositol 1,4,5-Trisphosphate Receptor Macromolecular Signaling Complex
J. Biol. Chem. 2002 277: 39397-39400. First Published on August 7, 2002; doi:10.1074/jbc.M207059200 [Abstract] [Full Text] [PDF]

Katsuhisa Inoue, Lina Zhuang, Dennis M. Maddox, Sylvia B. Smith, and Vadivel Ganapathy: Structure, Function, and Expression Pattern of a Novel Sodium-coupled Citrate Transporter (NaCT) Cloned from Mammalian Brain
J. Biol. Chem. 2002 277: 39469-39476. First Published on August 11, 2002; doi:10.1074/jbc.M207072200 [Abstract] [Full Text] [PDF]

Arnold H. van der Luit, Marianne Budde, Paula Ruurs, Marcel Verheij, and Wim J. van Blitterswijk: Alkyl-lysophospholipid Accumulates in Lipid Rafts and Induces Apoptosis via Raft-dependent Endocytosis and Inhibition of Phosphatidylcholine Synthesis
J. Biol. Chem. 2002 277: 39541-39547. First Published on August 14, 2002; doi:10.1074/jbc.M203176200 [Abstract] [Full Text] [PDF]

Mitsunori Fukuda, Eiko Kanno, Chika Saegusa, Yukie Ogata, and Taruho S. Kuroda: Slp4-a/Granuphilin-a Regulates Dense-core Vesicle Exocytosis in PC12 Cells
J. Biol. Chem. 2002 277: 39673-39678. First Published on August 9, 2002; doi:10.1074/jbc.M205349200 [Abstract] [Full Text] [PDF]

Funmei Yang, Xiao-bing Liu, Marlon Quinones, Peter C. Melby, Andrew Ghio, and David J. Haile: Regulation of Reticuloendothelial Iron Transporter MTP1 (Slc11a3) by Inflammation
J. Biol. Chem. 2002 277: 39786-39791. First Published on August 2, 2002; doi:10.1074/jbc.M201485200 [Abstract] [Full Text] [PDF]

Masahiro Ikeda, Eric Beitz, David Kozono, William B. Guggino, Peter Agre, and Masato Yasui: Characterization of Aquaporin-6 as a Nitrate Channel in Mammalian Cells. REQUIREMENT OF PORE-LINING RESIDUE THREONINE 63
J. Biol. Chem. 2002 277: 39873-39879. First Published on August 9, 2002; doi:10.1074/jbc.M207008200 [Abstract] [Full Text] [PDF]

Yajun Tang, Florina Zaitseva, Robert A. Lamb, and Lawrence H. Pinto: The Gate of the Influenza Virus M₂ Proton Channel Is Formed by a Single Tryptophan Residue
J. Biol. Chem. 2002 277: 39880-39886. First Published on August 14, 2002; doi:10.1074/jbc.M206582200 [Abstract] [Full Text] [PDF]

Marcela Hermoso, Christina M. Satterwhite, Yaniré Naty Andrade, Jorge Hidalgo, Sean M. Wilson, Burton Horowitz, and Joseph R. Hume: ClC-3 Is a Fundamental Molecular Component of Volume-sensitive Outwardly Rectifying Cl Channels and Volume Regulation in HeLa Cells and Xenopus laevis Oocytes
J. Biol. Chem. 2002 277: 40066-40074. First Published on August 14, 2002; doi:10.1074/jbc.M205132200 [Abstract] [Full Text] [PDF]

Agnieszka Swiatecka-Urban, Marc Duhaime, Bonita Coutermarsh, Katherine H. Karlson, James Collawn, Michal Milewski, Garry R. Cutting, William B. Guggino, George Langford, and Bruce A. Stanton: PDZ Domain Interaction Controls the Endocytic Recycling of the Cystic Fibrosis Transmembrane Conductance Regulator
J. Biol. Chem. 2002 277: 40099-40105. First Published on August 7, 2002; doi:10.1074/jbc.M206964200 [Abstract] [Full Text] [PDF]

Jyh-Yeuan Lee, Ina L. Urbatsch, Alan E. Senior, and Stephan Wilkens: Projection Structure of P-glycoprotein by Electron Microscopy. EVIDENCE FOR A CLOSED CONFORMATION OF THE NUCLEOTIDE BINDING DOMAINS
J. Biol. Chem. 2002 277: 40125-40131. First Published on August 5, 2002; doi:10.1074/jbc.M206871200 [Abstract] [Full Text] [PDF]

Arowu R. Tanaka, Kouichi Tanabe, Masashi Morita, Mikinori Kurisu, Yoshinori Kasiwayama, Michinori Matsuo, Noriyuki Kioka, Teruo Amachi, Tsuneo Imanaka, and Kazumitsu Ueda: ATP Binding/Hydrolysis by and Phosphorylation of Peroxisomal ATP-binding Cassette Proteins PMP70 (ABCD3) and Adrenoleukodystrophy Protein (ABCD1)
J. Biol. Chem. 2002 277: 40142-40147. First Published on August 9, 2002; doi:10.1074/jbc.M205079200 [Abstract] [Full Text] [PDF]

Mechanisms Of Signal Transduction:

Gilles Ouanounou, Michel Malo, Jacques Stinnakre, Arnold S. Kreger, and Jordi Molgó: Trachynilysin, a Neurosecretory Protein Isolated from Stonefish (Synanceia trachynis) Venom, Forms Nonselective Pores in the Membrane of NG108-15 Cells
J. Biol. Chem. 2002 277: 39119-39127. First Published on August 12, 2002; doi:10.1074/jbc.M203433200 [Abstract] [Full Text] [PDF]

Cristina Murga and Domingo F. Barber: Molecular Mechanisms of Pre-T Cell Receptor-induced Survival
J. Biol. Chem. 2002 277: 39156-39162. First Published on July 11, 2002; doi:10.1074/jbc.M203553200 [Abstract] [Full Text] [PDF]

Wonhee Jang, Binh Chiem, and Richard H. Gomer: A Secreted Cell Number Counting Factor Represses Intracellular Glucose Levels to Regulate Group Size in Dictyostelium
J. Biol. Chem. 2002 277: 39202-39208. First Published on August 2, 2002; doi:10.1074/jbc.M205635200 [Abstract] [Full Text] [PDF]

Sandra Guaita, Isabel Puig, Clara Francí, Marta Garrido, David Domínguez, Eduard Batlle, Elena Sancho, Shoukat Dedhar, Antonio García de Herreros, and Josep Baulida: Snail Induction of Epithelial to Mesenchymal Transition in Tumor Cells Is Accompanied by MUC1 Repression and ZEB1 Expression
J. Biol. Chem. 2002 277: 39209-39216. First Published on August 2, 2002; doi:10.1074/jbc.M206400200 [Abstract] [Full Text] [PDF]

Keith D. Kikawa, Derika R. Vidale, Robert L. Van Etten, and Michael S. Kinch: Regulation of the EphA2 Kinase by the Low Molecular Weight Tyrosine Phosphatase Induces Transformation
J. Biol. Chem. 2002 277: 39274-39279. First Published on August 6, 2002; doi:10.1074/jbc.M207127200 [Abstract] [Full Text] [PDF]

Xiaojuan Liu, Malabendu Jana, Subhajit Dasgupta, Sreenivas Koka, Jun He, Charles Wood, and Kalipada Pahan: Human Immunodeficiency Virus Type 1 (HIV-1) Tat Induces Nitric-oxide Synthase in Human Astroglia
J. Biol. Chem. 2002 277: 39312-39319. First Published on August 7, 2002; doi:10.1074/jbc.M205107200 [Abstract] [Full Text] [PDF]

Salamatu S. Mambula, Keya Sau, Philipp Henneke, Douglas T. Golenbock, and Stuart M. Levitz: Toll-like Receptor (TLR) Signaling in Response to Aspergillus fumigatus
J. Biol. Chem. 2002 277: 39320-39326. First Published on August 8, 2002; doi:10.1074/jbc.M201683200 [Abstract] [Full Text] [PDF]

Subhajit Dasgupta, Malabendu Jana, Xiaojuan Liu, and Kalipada Pahan: Myelin Basic Protein-primed T Cells Induce Nitric Oxide Synthase in Microglial Cells. IMPLICATIONS FOR MULTIPLE SCLEROSIS
J. Biol. Chem. 2002 277: 39327-39333. First Published on August 9, 2002; doi:10.1074/jbc.M111841200 [Abstract] [Full Text] [PDF]

Yi-Rong Chen, Jin Han, Rajashree Kori, A.-N. Tony Kong, and Tse-Hua Tan: Phenylethyl Isothiocyanate Induces Apoptotic Signaling via Suppressing Phosphatase Activity against c-Jun N-terminal Kinase
J. Biol. Chem. 2002 277: 39334-39342. First Published on August 8, 2002; doi:10.1074/jbc.M202070200 [Abstract] [Full Text] [PDF]

Todd R. Palmby, Karon Abe, and Channing J. Der: Critical Role of the Pleckstrin Homology and Cysteine-rich Domains in Vav Signaling and Transforming Activity
J. Biol. Chem. 2002 277: 39350-39359. First Published on August 12, 2002; doi:10.1074/jbc.M202641200 [Abstract] [Full Text] [PDF]

Saori Sato, Naoya Fujita, and Takashi Tsuruo: Regulation of Kinase Activity of 3-Phosphoinositide-dependent Protein Kinase-1 by Binding to 14-3-3
J. Biol. Chem. 2002 277: 39360-39367. First Published on August 12, 2002; doi:10.1074/jbc.M205141200 [Abstract] [Full Text] [PDF]

Olivier Diaz, Alexandre Berquand, Madeleine Dubois, Silvia Di Agostino, Claudio Sette, Sylvain Bourgoin, Michel Lagarde, Georges Némoz, and Annie-France Prigent: The Mechanism of Docosahexaenoic Acid-induced Phospholipase D Activation in Human Lymphocytes Involves Exclusion of the Enzyme from Lipid Rafts
J. Biol. Chem. 2002 277: 39368-39378. First Published on July 24, 2002; doi:10.1074/jbc.M202376200 [Abstract] [Full Text] [PDF]

Hui Zhang, Xiangming Zha, Yi Tan, Peter V. Hornbeck, Allison J. Mastrangelo, Dario R. Alessi, Roberto D. Polakiewicz, and Michael J. Comb: Phosphoprotein Analysis Using Antibodies Broadly Reactive against Phosphorylated Motifs
J. Biol. Chem. 2002 277: 39379-39387. First Published on July 31, 2002; doi:10.1074/jbc.M206399200 [Abstract] [Full Text] [PDF]

Darren G. Woodside, Achim Obergfell, Anupam Talapatra, David A. Calderwood, Sanford J. Shattil, and Mark H. Ginsberg: The N-terminal SH2 Domains of Syk and ZAP-70 Mediate Phosphotyrosine-independent Binding to Integrin $beta$ Cytoplasmic Domains
J. Biol. Chem. 2002 277: 39401-39408. First Published on August 8, 2002; doi:10.1074/jbc.M207657200 [Abstract] [Full Text] [PDF]

Mark Nellist, Miriam A. Goedbloed, Christa de Winter, Brenda Verhaaf, Anita Jankie, Arnold J. J. Reuser, Ans M. W. van den Ouweland, Peter van der Sluijs, and Dicky J. J. Halley: Identification and Characterization of the Interaction between Tuberin and 14-3-3 $zeta$
J. Biol. Chem. 2002 277: 39417-39424. First Published on August 9, 2002; doi:10.1074/jbc.M204802200 [Abstract] [Full Text] [PDF]

Bernhard Nieswandt, Valerie Schulte, Alexandra Zywietz, Marie-Pierre Gratacap, and Stefan Offermanns: Costimulation of G_i- and G₁₂/G₁₃-mediated Signaling Pathways Induces Integrin $alpha$ _IIb $beta$ ₃ Activation in Platelets
J. Biol. Chem. 2002 277: 39493-39498. First Published on August 14, 2002; doi:10.1074/jbc.M207256200 [Abstract] [Full Text] [PDF]

Lasse Foghsgaard, Ulrik Lademann, Dorte Wissing, Birgit Poulsen, and Marja Jäättelä: Cathepsin B Mediates Tumor Necrosis Factor-induced Arachidonic Acid Release in Tumor Cells
J. Biol. Chem. 2002 277: 39499-39506. First Published on August 15, 2002; doi:10.1074/jbc.M206669200 [Abstract] [Full Text] [PDF]

Eva Gonzalez, Ruqin Kou, Alison J. Lin, David E. Golan, and Thomas Michel: Subcellular Targeting and Agonist-induced Site-specific Phosphorylation of Endothelial Nitric-oxide Synthase
J. Biol. Chem. 2002 277: 39554-39560. First Published on August 19, 2002; doi:10.1074/jbc.M207299200 [Abstract] [Full Text] [PDF]

Michelle A. Peters, David C. Jackson, Brendan S. Crabb, and Glenn F. Browning: Chicken Anemia Virus VP2 Is a Novel Dual Specificity Protein Phosphatase
J. Biol. Chem. 2002 277: 39566-39573. First Published on July 31, 2002; doi:10.1074/jbc.M201752200 [Abstract] [Full Text] [PDF]

Ranjini Ramachander, Chongwoo A. Kim, Martin L. Phillips, Cameron D. Mackereth, Christopher D. Thanos, Lawrence P. McIntosh, and James U. Bowie: Oligomerization-dependent Association of the SAM Domains from Schizosaccharomyces pombe Byr2 and Ste4
J. Biol. Chem. 2002 277: 39585-39593. First Published on August 8, 2002; doi:10.1074/jbc.M207273200 [Abstract] [Full Text] [PDF]

Donato Goffredo, Dorotea Rigamonti, Marzia Tartari, Alberto De Micheli, Claudia Verderio, Michela Matteoli, Chiara Zuccato, and Elena Cattaneo: Calcium-dependent Cleavage of Endogenous Wild-type Huntingtin in Primary Cortical Neurons
J. Biol. Chem. 2002 277: 39594-39598. First Published on August 27, 2002; doi:10.1074/jbc.C200353200 [Abstract] [Full Text] [PDF]

Mingzhe Zheng and Paula J. McKeown-Longo: Regulation of HEF1 Expression and Phosphorylation by TGF- $beta$ 1 and Cell Adhesion
J. Biol. Chem. 2002 277: 39599-39608. First Published on August 19, 2002; doi:10.1074/jbc.M202263200 [Abstract] [Full Text] [PDF]

Iwona Szymkiewicz, Katarzyna Kowanetz, Philippe Soubeyran, Ana Dinarina, Stanley Lipkowitz, and Ivan Dikic: CIN85 Participates in Cbl-b-mediated Down-regulation of Receptor Tyrosine Kinases
J. Biol. Chem. 2002 277: 39666-39672. First Published on August 12, 2002; doi:10.1074/jbc.M205535200 [Abstract] [Full Text] [PDF]

Giuseppe Pandini, Francesco Frasca, Rossana Mineo, Laura Sciacca, Riccardo Vigneri, and Antonino Belfiore: Insulin/Insulin-like Growth Factor I Hybrid Receptors Have Different Biological Characteristics Depending on the Insulin Receptor Isoform Involved
J. Biol. Chem. 2002 277: 39684-39695. First Published on July 22, 2002; doi:10.1074/jbc.M202766200 [Abstract] [Full Text] [PDF]

Lilly Y. W. Bourguignon, Patrick A. Singleton, Hongbo Zhu, and Bo Zhou: Hyaluronan Promotes Signaling Interaction between CD44 and the Transforming Growth Factor $beta$ Receptor I in Metastatic Breast Tumor Cells
J. Biol. Chem. 2002 277: 39703-39712. First Published on July 26, 2002; doi:10.1074/jbc.M204320200 [Abstract] [Full Text] [PDF]

Andrés Maturana, Goedele Van Haasteren, Isabelle Piuz, Cyril Castelbou, Nicolas Demaurex, and Werner Schlegel: Spontaneous Calcium Oscillations Control c-fos Transcription via the Serum Response Element in Neuroendocrine Cells
J. Biol. Chem. 2002 277: 39713-39721. First Published on July 16, 2002; doi:10.1074/jbc.M200464200 [Abstract] [Full Text] [PDF]

Jun Zhou, Kamlesh Gupta, Joyce Yao, Keqiang Ye, Dulal Panda, Paraskevi Giannakakou, and Harish C. Joshi: Paclitaxel-resistant Human Ovarian Cancer Cells Undergo c-Jun NH₂-terminal Kinase-mediated Apoptosis in Response to Noscapine
J. Biol. Chem. 2002 277: 39777-39785. First Published on August 14, 2002; doi:10.1074/jbc.M203927200 [Abstract] [Full Text] [PDF]

Jianhe Huang, Quan Zhao, Sharon M. Mooney, and Frank S. Lee: Sequence Determinants in Hypoxia-inducible Factor-1 $alpha$ for Hydroxylation by the Prolyl Hydroxylases PHD1, PHD2, and PHD3
J. Biol. Chem. 2002 277: 39792-39800. First Published on August 13, 2002; doi:10.1074/jbc.M206955200 [Abstract] [Full Text] [PDF]

Ingo G. Janausch, Inma Garcia-Moreno, and Gottfried Unden: Function of DcuS from Escherichia coli as a Fumarate-stimulated Histidine Protein Kinase in Vitro
J. Biol. Chem. 2002 277: 39809-39814. First Published on August 6, 2002; doi:10.1074/jbc.M204482200 [Abstract] [Full Text] [PDF]

Pei-Jung Chung, Yu-Sun Chang, Chih-Lung Liang, and Ching-Liang Meng: Negative Regulation of Epstein-Barr Virus Latent Membrane Protein 1-mediated Functions by the Bone Morphogenetic Protein Receptor IA-binding Protein, BRAM1
J. Biol. Chem. 2002 277: 39850-39857. First Published on August 13, 2002; doi:10.1074/jbc.M206736200 [Abstract] [Full Text] [PDF]

Chie Suzuki, Gyo Murakami, Minoru Fukuchi, Tomomasa Shimanuki, Yuko Shikauchi, Takeshi Imamura, and Kohei Miyazono: Smurf1 Regulates the Inhibitory Activity of Smad7 by Targeting Smad7 to the Plasma Membrane
J. Biol. Chem. 2002 277: 39919-39925. First Published on July 31, 2002; doi:10.1074/jbc.M201901200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Hans-Jürgen Kreienkamp, Hannes Jon Larusson, Ines Witte, Thomas Roeder, Necla Birgül, Hans-Hinrich Hönck, Sönke Harder, Günter Ellinghausen, Friedrich Buck, and Dietmar Richter: Functional Annotation of Two Orphan G-protein-coupled Receptors, Drostar1 and -2, from Drosophila melanogaster and Their Ligands by Reverse Pharmacology
J. Biol. Chem. 2002 277: 39937-39943. First Published on August 6, 2002; doi:10.1074/jbc.M206931200 [Abstract] [Full Text] [PDF]

Edwin J. Weeber, Uwe Beffert, Chris Jones, Jill M. Christian, Eckart Förster, J. David Sweatt, and Joachim Herz: Reelin and ApoE Receptors Cooperate to Enhance Hippocampal Synaptic Plasticity and Learning
J. Biol. Chem. 2002 277: 39944-39952. First Published on August 7, 2002; doi:10.1074/jbc.M205147200 [Abstract] [Full Text] [PDF]

William Schubert, Philippe G. Frank, Scott E. Woodman, Hideyuki Hyogo, David E. Cohen, Chi-Wing Chow, and Michael P. Lisanti: Microvascular Hyperpermeability in Caveolin-1 ( $-$ / $-$ ) Knock-out Mice. TREATMENT WITH A SPECIFIC NITRIC-OXIDE SYNTHASE INHIBITOR, L-NAME, RESTORES NORMAL MICROVASCULAR PERMEABILITY IN Cav-1 NULL MICE
J. Biol. Chem. 2002 277: 40091-40098. First Published on August 7, 2002; doi:10.1074/jbc.M205948200 [Abstract] [Full Text] [PDF]

Chandrahasa R. Yellaturu, Manjula Bhanoori, Indira Neeli, and Gadiparthi N. Rao: N-Ethylmaleimide Inhibits Platelet-derived Growth Factor BB-stimulated Akt Phosphorylation via Activation of Protein Phosphatase 2A
J. Biol. Chem. 2002 277: 40148-40155. First Published on August 8, 2002; doi:10.1074/jbc.M206376200 [Abstract] [Full Text] [PDF]

Molecular Basis Of Cell and Developmental Biology:

Margaret Renaud-Young and Warren J. Gallin: In the First Extracellular Domain of E-cadherin, Heterophilic Interactions, but Not the Conserved His-Ala-Val Motif, Are Required for Adhesion
J. Biol. Chem. 2002 277: 39609-39616. First Published on August 1, 2002; doi:10.1074/jbc.M201256200 [Abstract] [Full Text] [PDF]

Takeshi Isoyama, Shusuke Kuge, and Akio Nomoto: The Core Protein of Hepatitis C Virus Is Imported into the Nucleus by Transport Receptor Kap123p but Inhibits Kap121p-dependent Nuclear Import of Yeast AP1-like Transcription Factor in Yeast Cells
J. Biol. Chem. 2002 277: 39634-39641. First Published on August 6, 2002; doi:10.1074/jbc.M203939200 [Abstract] [Full Text] [PDF]

Kohji Noguchi, Hidesuke Fukazawa, Yuko Murakami, and Yoshimasa Uehara: Nek11, a New Member of the NIMA Family of Kinases, Involved in DNA Replication and Genotoxic Stress Responses
J. Biol. Chem. 2002 277: 39655-39665. First Published on August 1, 2002; doi:10.1074/jbc.M204599200 [Abstract] [Full Text] [PDF]

Yusuke Furukawa, Noriko Nishimura, Yutaka Furukawa, Masaaki Satoh, Hitoshi Endo, Satsuki Iwase, Hisashi Yamada, Michio Matsuda, Yasuhiko Kano, and Mitsuru Nakamura: Apaf-1 Is a Mediator of E2F-1-induced Apoptosis
J. Biol. Chem. 2002 277: 39760-39768. First Published on July 30, 2002; doi:10.1074/jbc.M200805200 [Abstract] [Full Text] [PDF]

Veysel Ödemis, Barbara Moepps, Peter Gierschik, and Jürgen Engele: Interleukin-6 and cAMP Induce Stromal Cell-derived Factor-1 Chemotaxis in Astroglia by Up-regulating CXCR4 Cell Surface Expression. IMPLICATIONS FOR BRAIN INFLAMMATION
J. Biol. Chem. 2002 277: 39801-39808. First Published on August 8, 2002; doi:10.1074/jbc.M200472200 [Abstract] [Full Text] [PDF]

Takuji Yamao, Tetsuya Noguchi, Osamu Takeuchi, Uichi Nishiyama, Haruhiko Morita, Tetsuya Hagiwara, Hironori Akahori, Takashi Kato, Kenjiro Inagaki, Hideki Okazawa, Yoshitake Hayashi, Takashi Matozaki, Kiyoshi Takeda, Shizuo Akira, and Masato Kasuga: Negative Regulation of Platelet Clearance and of the Macrophage Phagocytic Response by the Transmembrane Glycoprotein SHPS-1
J. Biol. Chem. 2002 277: 39833-39839. First Published on August 7, 2002; doi:10.1074/jbc.M203287200 [Abstract] [Full Text] [PDF]

Tatyana Sklyarova, Veerle De Corte, Kris Meerschaert, Liesbeth Devriendt, Berlinda Vanloo, Juliet Bailey, Lynnette J. Cook, Mark Goethals, Jozef Van Damme, Magda Puype, Joël Vandekerckhove, and Jan Gettemans: Fragmin60 Encodes an Actin-binding Protein with a C2 Domain and Controls Actin Thr-203 Phosphorylation in Physarum Plasmodia and Sclerotia
J. Biol. Chem. 2002 277: 39840-39849. First Published on August 7, 2002; doi:10.1074/jbc.M207052200 [Abstract] [Full Text] [PDF]

María J. Calzada, María V. Alvarez, and José González-Rodríguez: Agonist-specific Structural Rearrangements of Integrin $alpha$ _IIb $beta$ ₃. CONFIRMATION OF THE BENT CONFORMATION IN PLATELETS AT REST AND AFTER ACTIVATION
J. Biol. Chem. 2002 277: 39899-39908. First Published on July 24, 2002; doi:10.1074/jbc.M205886200 [Abstract] [Full Text] [PDF]

Christoph Geisen and Tarik Möröy: The Oncogenic Activity of Cyclin E Is Not Confined to Cdk2 Activation Alone but Relies on Several Other, Distinct Functions of the Protein
J. Biol. Chem. 2002 277: 39909-39918. First Published on July 30, 2002; doi:10.1074/jbc.M205919200 [Abstract] [Full Text] [PDF]

Rumana Bahar, Jiyang O-Wang, Kiyoko Kawamura, Mika Seimiya, Yanqing Wang, Masahiko Hatano, Seiji Okada, Takeshi Tokuhisa, Takeshi Watanabe, and Masatoshi Tagawa: Growth Retardation, Polyploidy, and Multinucleation Induced by Clast3, a Novel Cell Cycle-regulated Protein
J. Biol. Chem. 2002 277: 40012-40019. First Published on July 29, 2002; doi:10.1074/jbc.M205345200 [Abstract] [Full Text] [PDF]

Olga Ostrovsky, Eyal Bengal, and Ami Aronheim: Induction of Terminal Differentiation by the c-Jun Dimerization Protein JDP2 in C2 Myoblasts and Rhabdomyosarcoma Cells
J. Biol. Chem. 2002 277: 40043-40054. First Published on August 8, 2002; doi:10.1074/jbc.M205494200 [Abstract] [Full Text] [PDF]

Additions and Corrections:

Susanne Schneider, Hans-Rudolf Hotz, and Beate Schwer: Characterization of dominant-negative mutants of the DEAH-box splicing factors Prp22 and Prp16.
J. Biol. Chem. 2002 277: 40163-40166. [Full Text] [PDF]

Lara Joubert, Sylvie Claeysen, Michèle Sebben, Anne-Sophie Bessis, Robin D. Clark, Renee S. Martin, Joël Bockaert, and Aline Dumuis: A 5-HT₄ receptor transmembrane network implicated in the activity of inverse agonists but not agonists.
J. Biol. Chem. 2002 277: 40167. [Full Text] [PDF]

Paola Monti, Paola Campomenosi, Yari Ciribilli, Raffaella Iannone, Alberto Inga, Dharini Shah, Gina Scott, Philip A. Burns, Paola Menichini, Angelo Abbondandolo, Barry Gold, and Gilberto Fronza: Influences of base excision repair defects on the lethality and mutagenicity induced by Me-lex, a sequence selective N3-adenine methylating agent.
J. Biol. Chem. 2002 277: 40167a. [Full Text] [PDF]

Akiko Kimura, Silvia Mora, Satoshi Shigematsu, Jeffrey E. Pessin, and Alan R. Saltiel: The insulin receptor catalyzes the tyrosine phosphorylation of caveolin-1.
J. Biol. Chem. 2002 277: 40167b. [Full Text] [PDF]

Jihee Kim, Andrea D. Eckhart, Satoru Eguchi, and Walter J. Koch: $beta$ -Adrenergic receptor-mediated DNA synthesis in cardiac fibroblasts is dependent on transactivation of the epidermal growth factor receptor and subsequent activation of extracellular signal-regulated kinases.
J. Biol. Chem. 2002 277: 40168. [Full Text] [PDF]