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The cover figure represents the structure of the ATP synthase complex from E. coli. The Reflections by Paul Boyer published in this issue (for details see pages 39045-39061) describes the discovery and history of research on oxidative phosphorylation. He also details the development of the binding change mechanism for oxidative phosphorylation, the discovery for which he received a share of the Nobel Prize in Chemistry in 1997. The figure was kindly provided by Richard Cross.
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