JBC Focus on PI3-Kinase with Echelon
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Table of Contents: Nov 22 2002; 277 (47)   [Index by Author]  [Cover Figure and Caption]
       Accelerated Publications
       DNA: Replication Repair and Recombination
       Genes: Structure and Regulation
       RNA: Structure Metabolism and Catalysis
       Protein Synthesis Post-Translation Modification and Degradation
       Genomics Proteomics and Bioinformatics
       Protein Structure and Folding
       Enzyme Catalysis and Regulation
       Metabolism and Bioenergetics
       Glycobiology and Extracellular Matrices
       Lipids and Lipoproteins
       Membrane Transport Structure Function and Biogenesis
       Mechanisms Of Signal Transduction
       Molecular Basis Of Cell and Developmental Biology
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Accelerated Publications:

Adrian C. Apetri and Witold K. Surewicz
Kinetic Intermediate in the Folding of Human Prion Protein
J. Biol. Chem. 2002 277: 44589-44592. First Published on September 27, 2002; 10.1074/jbc.C200507200 [Abstract] [Full Text] [PDF]  

Yong Li, Ken Inoki, Raymond Yeung, and Kun-Liang Guan
Regulation of TSC2 by 14-3-3 Binding
J. Biol. Chem. 2002 277: 44593-44596. First Published on October 2, 2002; 10.1074/jbc.C200510200 [Abstract] [Full Text] [PDF]  


DNA: Replication Repair and Recombination:

Shisheng Li and Michael J. Smerdon
Nucleosome Structure and Repair of N-Methylpurines in the GAL1-10 Genes of Saccharomyces cerevisiae
J. Biol. Chem. 2002 277: 44651-44659. First Published on September 19, 2002; 10.1074/jbc.M206623200 [Abstract] [Full Text] [PDF]  

Alexander I. Alexandrov, Michael R. Botchan, and Nicholas R. Cozzarelli
Characterization of Simian Virus 40 T-antigen Double Hexamers Bound to a Replication Fork. THE ACTIVE FORM OF THE HELICASE
J. Biol. Chem. 2002 277: 44886-44897. First Published on September 19, 2002; 10.1074/jbc.M207022200 [Abstract] [Full Text] [PDF]  

Lyudmila I. Rachek, Valentina I. Grishko, Sergiy I. Musiyenko, Mark R. Kelley, Susan P. LeDoux, and Glenn L. Wilson
Conditional Targeting of the DNA Repair Enzyme hOGG1 into Mitochondria
J. Biol. Chem. 2002 277: 44932-44937. First Published on September 19, 2002; 10.1074/jbc.M208770200 [Abstract] [Full Text] [PDF]  

Pablo Hilario, Shixiang Yan, Brian E. Hingerty, Suse Broyde, and Ashis K. Basu
Comparative Mutagenesis of the C8-Guanine Adducts of 1-Nitropyrene and 1,6- and 1,8-Dinitropyrene in a CpG Repeat Sequence. A SLIPPED FRAMESHIFT INTERMEDIATE MODEL FOR DINUCLEOTIDE DELETION
J. Biol. Chem. 2002 277: 45068-45074. First Published on September 17, 2002; 10.1074/jbc.M208103200 [Abstract] [Full Text] [PDF] Supplemental Data  

Jong-Soo Kim, Tatiana B. Krasieva, Vickie LaMorte, A. Malcolm R. Taylor, and Kyoko Yokomori
Specific Recruitment of Human Cohesin to Laser-induced DNA Damage
J. Biol. Chem. 2002 277: 45149-45153. First Published on September 12, 2002; 10.1074/jbc.M209123200 [Abstract] [Full Text] [PDF]  

Kristina H. Schmidt, Katrina L. Derry, and Richard D. Kolodner
Saccharomyces cerevisiae RRM3, a 5' to 3' DNA Helicase, Physically Interacts with Proliferating Cell Nuclear Antigen
J. Biol. Chem. 2002 277: 45331-45337. First Published on September 17, 2002; 10.1074/jbc.M207263200 [Abstract] [Full Text] [PDF]  

Hui-Min Tseng and Alan E. Tomkinson
A Physical and Functional Interaction between Yeast Pol4 and Dnl4-Lif1 Links DNA Synthesis and Ligation in Nonhomologous End Joining
J. Biol. Chem. 2002 277: 45630-45637. First Published on September 13, 2002; 10.1074/jbc.M206861200 [Abstract] [Full Text] [PDF]  


Genes: Structure and Regulation:

Kunihiko Yasuda, Kazunori Hirayoshi, Hiromi Hirata, Hiroshi Kubota, Nobuko Hosokawa, and Kazuhiro Nagata
The Kruppel-like Factor Zf9 and Proteins in the Sp1 Family Regulate the Expression of HSP47, a Collagen-specific Molecular Chaperone
J. Biol. Chem. 2002 277: 44613-44622. First Published on September 13, 2002; 10.1074/jbc.M208558200 [Abstract] [Full Text] [PDF]  

Maryse Duquette and Odette Laneuville
Translational Regulation of Prostaglandin Endoperoxide H Synthase-1 mRNA in Megakaryocytic MEG-01 Cells. SPECIFIC PROTEIN BINDING TO A CONSERVED 20-NUCLEOTIDE CIS ELEMENT IN THE 3'-UNTRANSLATED REGION
J. Biol. Chem. 2002 277: 44631-44637. First Published on September 16, 2002; 10.1074/jbc.M207007200 [Abstract] [Full Text] [PDF]  

Hiromi Sasaki, Hideyo Sato, Kazumi Kuriyama-Matsumura, Kanako Sato, Kanako Maebara, Hongyu Wang, Michiko Tamba, Ken Itoh, Masayuki Yamamoto, and Shiro Bannai
Electrophile Response Element-mediated Induction of the Cystine/Glutamate Exchange Transporter Gene Expression
J. Biol. Chem. 2002 277: 44765-44771. First Published on September 13, 2002; 10.1074/jbc.M208704200 [Abstract] [Full Text] [PDF]  

Christina Tzagarakis-Foster, Romas Geleziunas, Abderrahim Lomri, Jinping An, and Dale C. Leitman
Estradiol Represses Human T-cell Leukemia Virus Type 1 Tax Activation of Tumor Necrosis Factor-alpha Gene Transcription
J. Biol. Chem. 2002 277: 44772-44777. First Published on September 16, 2002; 10.1074/jbc.M205355200 [Abstract] [Full Text] [PDF]  

Tae Ho Lee, Shelly Lwu, Jungho Kim, and Jerry Pelletier
Inhibition of Wilms Tumor 1 Transactivation by Bone Marrow Zinc Finger 2, a Novel Transcriptional Repressor
J. Biol. Chem. 2002 277: 44826-44837. First Published on September 17, 2002; 10.1074/jbc.M205667200 [Abstract] [Full Text] [PDF]  

Xianrong Mao, Andrea M. Moerman, and Steven W. Barger
Neuronal kappa B-binding Factors Consist of Sp1-related Proteins. FUNCTIONAL IMPLICATIONS FOR AUTOREGULATION OF N-METHYL-D-ASPARTATE RECEPTOR-1 EXPRESSION
J. Biol. Chem. 2002 277: 44911-44919. First Published on September 18, 2002; 10.1074/jbc.M204292200 [Abstract] [Full Text] [PDF]  

Fusheng Li, Todd Macfarlan, Randall N. Pittman, and Debabrata Chakravarti
Ataxin-3 Is a Histone-binding Protein with Two Independent Transcriptional Corepressor Activities
J. Biol. Chem. 2002 277: 45004-45012. First Published on September 23, 2002; 10.1074/jbc.M205259200 [Abstract] [Full Text] [PDF]  

Lisa A. McPherson, Alexander V. Loktev, and Ronald J. Weigel
Tumor Suppressor Activity of AP2alpha Mediated through a Direct Interaction with p53
J. Biol. Chem. 2002 277: 45028-45033. First Published on September 10, 2002; 10.1074/jbc.M208924200 [Abstract] [Full Text] [PDF]  

Cyril Gueydan, Corinne Wauquier, Christelle De Mees, Georges Huez, and Véronique Kruys
Identification of Ribosomal Proteins Specific to Higher Eukaryotic Organisms
J. Biol. Chem. 2002 277: 45034-45040. First Published on August 28, 2002; 10.1074/jbc.M208551200 [Abstract] [Full Text] [PDF]  

Masahiko Kishimoto, Yasuhiko Okimura, Kazuhiro Yagita, Genzo Iguchi, Mariko Fumoto, Keiji Iida, Hidesuke Kaji, Hitoshi Okamura, and Kazuo Chihara
Novel Function of the Transactivation Domain of a Pituitary-specific Transcription Factor, Pit-1
J. Biol. Chem. 2002 277: 45141-45148. First Published on August 27, 2002; 10.1074/jbc.M202991200 [Abstract] [Full Text] [PDF]  

Santasabuj Das, Jun-Hsiang Lin, Joseph Papamatheakis, Yuri Sykulev, and Philip N. Tsichlis
Differential Splicing Generates Tvl-1/RFXANK Isoforms with Different Functions
J. Biol. Chem. 2002 277: 45172-45180. First Published on September 4, 2002; 10.1074/jbc.M204117200 [Abstract] [Full Text] [PDF]  

Geon Tae Park, Susan E. Lim, Shyh-Ing Jang, and Maria I. Morasso
Suprabasin, a Novel Epidermal Differentiation Marker and Potential Cornified Envelope Precursor
J. Biol. Chem. 2002 277: 45195-45202. First Published on September 12, 2002; 10.1074/jbc.M205380200 [Abstract] [Full Text] [PDF]  

Xiaohui Zhang, Lixia Gan, Haiyun Pan, Shaodong Guo, Xiaowei He, Steven T. Olson, Andrew Mesecar, Stephen Adam, and Terry G. Unterman
Phosphorylation of Serine 256 Suppresses Transactivation by FKHR (FOXO1) by Multiple Mechanisms. DIRECT AND INDIRECT EFFECTS ON NUCLEAR/CYTOPLASMIC SHUTTLING AND DNA BINDING
J. Biol. Chem. 2002 277: 45276-45284. First Published on September 12, 2002; 10.1074/jbc.M208063200 [Abstract] [Full Text] [PDF]  

Andrew P. Weir, Edward A. Burton, Graham Harrod, and Kay E. Davies
A- and B-utrophin Have Different Expression Patterns and Are Differentially Up-regulated in mdx Muscle
J. Biol. Chem. 2002 277: 45285-45290. First Published on September 15, 2002; 10.1074/jbc.M205177200 [Abstract] [Full Text] [PDF]  

Ingo Melzner, Vanessa Scott, Karola Dorsch, Pamela Fischer, Martin Wabitsch, Silke Brüderlein, Cornelia Hasel, and Peter Möller
Leptin Gene Expression in Human Preadipocytes Is Switched on by Maturation-induced Demethylation of Distinct CpGs in Its Proximal Promoter
J. Biol. Chem. 2002 277: 45420-45427. First Published on September 3, 2002; 10.1074/jbc.M208511200 [Abstract] [Full Text] [PDF]  

Wenjun Zhang, Tatiana A. Yatskievych, Xu Cao, and Parker B. Antin
Regulation of Hex Gene Expression by a Smads-dependent Signaling Pathway
J. Biol. Chem. 2002 277: 45435-45441. First Published on September 20, 2002; 10.1074/jbc.M208056200 [Abstract] [Full Text] [PDF]  

Hiroshi Yukitake, Makoto Furusawa, Takahiro Taira, Sanae M. M. Iguchi-Ariga, and Hiroyoshi Ariga
AAT-1, a Novel Testis-specific AMY-1-binding Protein, Forms a Quaternary Complex with AMY-1, A-kinase Anchor Protein 84, and a Regulatory Subunit of cAMP-dependent Protein Kinase and Is Phosphorylated by Its Kinase
J. Biol. Chem. 2002 277: 45480-45492. First Published on September 9, 2002; 10.1074/jbc.M206201200 [Abstract] [Full Text] [PDF]  

Sebastiaan Werten, André Mitschler, Christophe Romier, Yann-Gaël Gangloff, Sylvie Thuault, Irwin Davidson, and Dino Moras
Crystal Structure of a Subcomplex of Human Transcription Factor TFIID Formed by TATA Binding Protein-associated Factors hTAF4 (hTAFII135) and hTAF12 (hTAFII20)
J. Biol. Chem. 2002 277: 45502-45509. First Published on September 16, 2002; 10.1074/jbc.M206587200 [Abstract] [Full Text] [PDF]  

Sylvie Thuault, Yann-Gaël Gangloff, Jay Kirchner, Steven Sanders, Sebastiaan Werten, Christophe Romier, P. Anthony Weil, and Irwin Davidson
Functional Analysis of the TFIID-specific Yeast TAF4 (yTAFII48) Reveals an Unexpected Organization of Its Histone-fold Domain
J. Biol. Chem. 2002 277: 45510-45517. First Published on September 16, 2002; 10.1074/jbc.M206556200 [Abstract] [Full Text] [PDF]  

Jack T. Rogers, Jeffrey D. Randall, Catherine M. Cahill, Paul S. Eder, Xudong Huang, Hiromi Gunshin, Lorene Leiter, Jay McPhee, Satinder S. Sarang, Tada Utsuki, Nigel H. Greig, Debomoy K. Lahiri, Rudolph E. Tanzi, Ashley I. Bush, Tony Giordano, and Steve R. Gullans
An Iron-responsive Element Type II in the 5'-Untranslated Region of the Alzheimer's Amyloid Precursor Protein Transcript
J. Biol. Chem. 2002 277: 45518-45528. First Published on August 26, 2002; 10.1074/jbc.M207435200 [Abstract] [Full Text] [PDF]  

Musheng Zeng, Ajay Kumar, Gaoyuan Meng, Qingshen Gao, Goberdhan Dimri, David Wazer, Hamid Band, and Vimla Band
Human Papilloma Virus 16 E6 Oncoprotein Inhibits Retinoic X Receptor-mediated Transactivation by Targeting Human ADA3 Coactivator
J. Biol. Chem. 2002 277: 45611-45618. First Published on September 15, 2002; 10.1074/jbc.M208447200 [Abstract] [Full Text] [PDF]  

Samuel Y. Hou, Shwu-Yuan Wu, and Cheng-Ming Chiang
Transcriptional Activity among High and Low Risk Human Papillomavirus E2 Proteins Correlates with E2 DNA Binding
J. Biol. Chem. 2002 277: 45619-45629. First Published on September 17, 2002; 10.1074/jbc.M206829200 [Abstract] [Full Text] [PDF]  


RNA: Structure Metabolism and Catalysis:

Pok Kwan Yang, Giuseppe Rotondo, Tanya Porras, Pierre Legrain, and Guillaume Chanfreau
The Shq1p·Naf1p Complex Is Required for Box H/ACA Small Nucleolar Ribonucleoprotein Particle Biogenesis
J. Biol. Chem. 2002 277: 45235-45242. First Published on September 11, 2002; 10.1074/jbc.M207669200 [Abstract] [Full Text] [PDF]  

Fumitaka Momose, Tadasuke Naito, Keiichi Yano, Seiji Sugimoto, Yuko Morikawa, and Kyosuke Nagata
Identification of Hsp90 as a Stimulatory Host Factor Involved in Influenza Virus RNA Synthesis
J. Biol. Chem. 2002 277: 45306-45314. First Published on September 10, 2002; 10.1074/jbc.M206822200 [Abstract] [Full Text] [PDF]  

Sabina Piccininni, Agoritsa Varaklioti, Maria Nardelli, Bhuvanesh Dave, Kevin D. Raney, and John E. G. McCarthy
Modulation of the Hepatitis C Virus RNA-dependent RNA Polymerase Activity by the Non-Structural (NS) 3 Helicase and the NS4B Membrane Protein
J. Biol. Chem. 2002 277: 45670-45679. First Published on September 15, 2002; 10.1074/jbc.M204124200 [Abstract] [Full Text] [PDF]  


Protein Synthesis Post-Translation Modification and Degradation:

Hongwei Li, Sungmin Park, Britta Kilburn, Mary Anne Jelinek, Agnes Henschen-Edman, Dana W. Aswad, Michael R. Stallcup, and Ite A. Laird-Offringa
Lipopolysaccharide-induced Methylation of HuR, an mRNA-stabilizing Protein, by CARM1
J. Biol. Chem. 2002 277: 44623-44630. First Published on September 16, 2002; 10.1074/jbc.M206187200 [Abstract] [Full Text] [PDF]  

Sven Lammich, Masayasu Okochi, Masatoshi Takeda, Christoph Kaether, Anja Capell, Ann-Katrin Zimmer, Dieter Edbauer, Jochen Walter, Harald Steiner, and Christian Haass
Presenilin-dependent Intramembrane Proteolysis of CD44 Leads to the Liberation of Its Intracellular Domain and the Secretion of an Abeta -like Peptide
J. Biol. Chem. 2002 277: 44754-44759. First Published on September 9, 2002; 10.1074/jbc.M206872200 [Abstract] [Full Text] [PDF]  

Rauf Latif, Peter Graves, and Terry F. Davies
Ligand-dependent Inhibition of Oligomerization at the Human Thyrotropin Receptor
J. Biol. Chem. 2002 277: 45059-45067. First Published on September 9, 2002; 10.1074/jbc.M206693200 [Abstract] [Full Text] [PDF]  

Jean-Rémy Courbard, Frédéric Fiore, José Adélaïde, Jean-Paul Borg, Daniel Birnbaum, and Vincent Ollendorff
Interaction between Two Ubiquitin-Protein Isopeptide Ligases of Different Classes, CBLC and AIP4/ITCH
J. Biol. Chem. 2002 277: 45267-45275. First Published on September 10, 2002; 10.1074/jbc.M206460200 [Abstract] [Full Text] [PDF]  

David M. Selva, Kevin N. Hogeveen, Koji Seguchi, Francis Tekpetey, and Geoffrey L. Hammond
A Human Sex Hormone-binding Globulin Isoform Accumulates in the Acrosome during Spermatogenesis
J. Biol. Chem. 2002 277: 45291-45298. First Published on September 13, 2002; 10.1074/jbc.M205903200 [Abstract] [Full Text] [PDF]  

Lim Shen Kiat, Kam Man Hui, and Ganesan Gopalan
Aurora-A Kinase Interacting Protein (AIP), a Novel Negative Regulator of Human Aurora-A Kinase
J. Biol. Chem. 2002 277: 45558-45565. First Published on September 18, 2002; 10.1074/jbc.M206820200 [Abstract] [Full Text] [PDF]  


Genomics Proteomics and Bioinformatics:

Adrian Auf der Maur, Christian Zahnd, Franziska Fischer, Silvia Spinelli, Annemarie Honegger, Christian Cambillau, Dominik Escher, Andreas Plückthun, and Alcide Barberis
Direct in Vivo Screening of Intrabody Libraries Constructed on a Highly Stable Single-chain Framework
J. Biol. Chem. 2002 277: 45075-45085. First Published on September 4, 2002; 10.1074/jbc.M205264200 [Abstract] [Full Text] [PDF]  

Yutaka Shimomura, Noriaki Aoki, Jürgen Schweizer, Lutz Langbein, Michael A. Rogers, Hermelita Winter, and Masaaki Ito
Polymorphisms in the Human High Sulfur Hair Keratin-associated Protein 1, KAP1, Gene Family
J. Biol. Chem. 2002 277: 45493-45501. First Published on September 11, 2002; 10.1074/jbc.M206398200 [Abstract] [Full Text] [PDF]  


Protein Structure and Folding:

Soon-Young Kim, Suveena Sharma, Joel R. Hoskins, and Sue Wickner
Interaction of the DnaK and DnaJ Chaperone System with a Native Substrate, P1 RepA
J. Biol. Chem. 2002 277: 44778-44783. First Published on September 16, 2002; 10.1074/jbc.M206176200 [Abstract] [Full Text] [PDF]  

Johan Lantto and Mats Ohlin
Functional Consequences of Insertions and Deletions in the Complementarity-determining Regions of Human Antibodies
J. Biol. Chem. 2002 277: 45108-45114. First Published on September 16, 2002; 10.1074/jbc.M208401200 [Abstract] [Full Text] [PDF]  

George V. Avvakumov, Irina Grishkovskaya, Yves A. Muller, and Geoffrey L. Hammond
Crystal Structure of Human Sex Hormone-binding Globulin in Complex with 2-Methoxyestradiol Reveals the Molecular Basis for High Affinity Interactions with C-2 Derivatives of Estradiol
J. Biol. Chem. 2002 277: 45219-45225. First Published on September 11, 2002; 10.1074/jbc.M207762200 [Abstract] [Full Text] [PDF]  

Christina Meyer, Luigi Notari, and S. Patricia Becerra
Mapping the Type I Collagen-binding Site on Pigment Epithelium-derived Factor. IMPLICATIONS FOR ITS ANTIANGIOGENIC ACTIVITY
J. Biol. Chem. 2002 277: 45400-45407. First Published on September 16, 2002; 10.1074/jbc.M208339200 [Abstract] [Full Text] [PDF]  

Colin W. Garvie, Miles A. Pufall, Barbara J. Graves, and Cynthia Wolberger
Structural Analysis of the Autoinhibition of Ets-1 and Its Role in Protein Partnerships
J. Biol. Chem. 2002 277: 45529-45536. First Published on September 6, 2002; 10.1074/jbc.M206327200 [Abstract] [Full Text] [PDF]  

Isabelle Parrot, Philip C. Huang, and Chaitan Khosla
Circular Dichroism and Nuclear Magnetic Resonance Spectroscopic Analysis of Immunogenic Gluten Peptides and Their Analogs
J. Biol. Chem. 2002 277: 45572-45578. First Published on September 24, 2002; 10.1074/jbc.M207606200 [Abstract] [Full Text] [PDF] Supplemental Data  


Enzyme Catalysis and Regulation:

Zoltán Szeltner, Dean Rea, Tünde Juhász, Veronika Renner, Zoltán Mucsi, György Orosz, Vilmos Fülöp, and László Polgár
Substrate-dependent Competency of the Catalytic Triad of Prolyl Oligopeptidase
J. Biol. Chem. 2002 277: 44597-44605. First Published on September 11, 2002; 10.1074/jbc.M207386200 [Abstract] [Full Text] [PDF]  

Giuseppe Battaini, Enrico Monzani, Luigi Casella, Emanuela Lonardi, Armand W. J. W. Tepper, Gerard W. Canters, and Luigi Bubacco
Tyrosinase-catalyzed Oxidation of Fluorophenols
J. Biol. Chem. 2002 277: 44606-44612. First Published on September 13, 2002; 10.1074/jbc.M207829200 [Abstract] [Full Text] [PDF]  

Junshun Zhang and Gloria C. Ferreira
Transient State Kinetic Investigation of 5-Aminolevulinate Synthase Reaction Mechanism
J. Biol. Chem. 2002 277: 44660-44669. First Published on August 20, 2002; 10.1074/jbc.M203584200 [Abstract] [Full Text] [PDF]  

Saumendra N. Sarkar, Srabani Pal, and Ganes C. Sen
Crisscross Enzymatic Reaction between the Two Molecules in the Active Dimeric P69 Form of the 2'-5' Oligodenylate Synthetase
J. Biol. Chem. 2002 277: 44760-44764. First Published on September 9, 2002; 10.1074/jbc.M207126200 [Abstract] [Full Text] [PDF]  

Klaus Richter, Jochen Reinstein, and Johannes Buchner
N-terminal Residues Regulate the Catalytic Efficiency of the Hsp90 ATPase Cycle
J. Biol. Chem. 2002 277: 44905-44910. First Published on September 13, 2002; 10.1074/jbc.M208457200 [Abstract] [Full Text] [PDF]  

Francesca Sparla, Paolo Pupillo, and Paolo Trost
The C-terminal Extension of Glyceraldehyde-3-phosphate Dehydrogenase Subunit B Acts as an Autoinhibitory Domain Regulated by Thioredoxins and Nicotinamide Adenine Dinucleotide
J. Biol. Chem. 2002 277: 44946-44952. First Published on September 20, 2002; 10.1074/jbc.M206873200 [Abstract] [Full Text] [PDF]  

Masakazu Sugishima, Hiroshi Sakamoto, Yuichiro Higashimoto, Yoshiaki Omata, Shunsuke Hayashi, Masato Noguchi, and Keiichi Fukuyama
Crystal Structure of Rat Heme Oxygenase-1 in Complex with Heme Bound to Azide. IMPLICATION FOR REGIOSPECIFIC HYDROXYLATION OF HEME AT THE alpha -MESO CARBON
J. Biol. Chem. 2002 277: 45086-45090. First Published on September 15, 2002; 10.1074/jbc.M207267200 [Abstract] [Full Text] [PDF]  

Meredith Teilhet Morris, Alexandra Coppin, Stanislas Tomavo, and Vern B. Carruthers
Functional Analysis of Toxoplasma gondii Protease Inhibitor 1
J. Biol. Chem. 2002 277: 45259-45266. First Published on September 11, 2002; 10.1074/jbc.M205517200 [Abstract] [Full Text] [PDF]  

Laurent Thion, Emmanuelle Laurine, Monique Erard, Odile Burlet-Schiltz, Bernard Monsarrat, Jean-Michel Masson, and Isabelle Saves
The Two-step Cleavage Activity of PI-TfuI Intein Endonuclease Demonstrated by Matrix-assisted Laser Desorption Ionization Time-of-flight Mass Spectrometry
J. Biol. Chem. 2002 277: 45442-45450. First Published on September 17, 2002; 10.1074/jbc.M203507200 [Abstract] [Full Text] [PDF]  

James B. Thoden, Jungwook Kim, Frank M. Raushel, and Hazel M. Holden
Structural and Kinetic Studies of Sugar Binding to Galactose Mutarotase from Lactococcus lactis
J. Biol. Chem. 2002 277: 45458-45465. First Published on September 5, 2002; 10.1074/jbc.M208395200 [Abstract] [Full Text] [PDF]  

Binnur Eroglu and Susan G. Powers-Lee
Unmasking a Functional Allosteric Domain in an Allosterically Nonresponsive Carbamoyl-phosphate Synthetase
J. Biol. Chem. 2002 277: 45466-45472. First Published on September 19, 2002; 10.1074/jbc.M208185200 [Abstract] [Full Text] [PDF]  

Françoise Haeseleer, Geeng-Fu Jang, Yoshikazu Imanishi, Carola A. G. G. Driessen, Masazumi Matsumura, Peter S. Nelson, and Krzysztof Palczewski
Dual-substrate Specificity Short Chain Retinol Dehydrogenases from the Vertebrate Retina
J. Biol. Chem. 2002 277: 45537-45546. First Published on September 10, 2002; 10.1074/jbc.M208882200 [Abstract] [Full Text] [PDF] Supplemental Data  


Metabolism and Bioenergetics:

Christa J. Maynard, Roberto Cappai, Irene Volitakis, Robert A. Cherny, Anthony R. White, Konrad Beyreuther, Colin L. Masters, Ashley I. Bush, and Qiao-Xin Li
Overexpression of Alzheimer's Disease Amyloid-beta Opposes the Age-dependent Elevations of Brain Copper and Iron
J. Biol. Chem. 2002 277: 44670-44676. First Published on September 4, 2002; 10.1074/jbc.M204379200 [Abstract] [Full Text] [PDF]  

Arvind Gill, Ningguo Gao, and Mark A. Lehrman
Rapid Activation of Glycogen Phosphorylase by the Endoplasmic Reticulum Unfolded Protein Response
J. Biol. Chem. 2002 277: 44747-44753. First Published on September 9, 2002; 10.1074/jbc.M205001200 [Abstract] [Full Text] [PDF]  

Julie St-Pierre, Julie A. Buckingham, Stephen J. Roebuck, and Martin D. Brand
Topology of Superoxide Production from Different Sites in the Mitochondrial Electron Transport Chain
J. Biol. Chem. 2002 277: 44784-44790. First Published on September 16, 2002; 10.1074/jbc.M207217200 [Abstract] [Full Text] [PDF]  

Tanya Jonassen, Beth N. Marbois, Kym F. Faull, Catherine F. Clarke, and Pamela L. Larsen
Development and Fertility in Caenorhabditis elegans clk-1 Mutants Depend upon Transport of Dietary Coenzyme Q8 to Mitochondria
J. Biol. Chem. 2002 277: 45020-45027. First Published on September 24, 2002; 10.1074/jbc.M204758200 [Abstract] [Full Text] [PDF]  

Hiroyuki Kasahara, Atsushi Hanada, Tomohisa Kuzuyama, Motoki Takagi, Yuji Kamiya, and Shinjiro Yamaguchi
Contribution of the Mevalonate and Methylerythritol Phosphate Pathways to the Biosynthesis of Gibberellins in Arabidopsis
J. Biol. Chem. 2002 277: 45188-45194. First Published on September 12, 2002; 10.1074/jbc.M208659200 [Abstract] [Full Text] [PDF]  

Christopher R. McCudden, Kathi A. James, Craig Hasilo, and Graham F. Wagner
Characterization of Mammalian Stanniocalcin Receptors. MITOCHONDRIAL TARGETING OF LIGAND AND RECEPTOR FOR REGULATION OF CELLULAR METABOLISM
J. Biol. Chem. 2002 277: 45249-45258. First Published on September 9, 2002; 10.1074/jbc.M205954200 [Abstract] [Full Text] [PDF]  


Glycobiology and Extracellular Matrices:

Jürgen Stolz and Sean Munro
The Components of the Saccharomyces cerevisiae Mannosyltransferase Complex M-Pol I Have Distinct Functions in Mannan Synthesis
J. Biol. Chem. 2002 277: 44801-44808. First Published on September 15, 2002; 10.1074/jbc.M208023200 [Abstract] [Full Text] [PDF]  

Yamato Kikkawa, Casey L. Moulson, Ismo Virtanen, and Jeffrey H. Miner
Identification of the Binding Site for the Lutheran Blood Group Glycoprotein on Laminin alpha 5 through Expression of Chimeric Laminin Chains in Vivo
J. Biol. Chem. 2002 277: 44864-44869. First Published on September 18, 2002; 10.1074/jbc.M208731200 [Abstract] [Full Text] [PDF]  

Sarah Netzel-Arnett, David J. Mitola, Susan S. Yamada, Kali Chrysovergis, Kenn Holmbeck, Henning Birkedal-Hansen, and Thomas H. Bugge
Collagen Dissolution by Keratinocytes Requires Cell Surface Plasminogen Activation and Matrix Metalloproteinase Activity
J. Biol. Chem. 2002 277: 45154-45161. First Published on August 20, 2002; 10.1074/jbc.M206354200 [Abstract] [Full Text] [PDF]  

Kashi Javaherian, Susan Y. Park, Winfried F. Pickl, Kenneth R. LaMontagne, Robert Tjin Tham Sjin, Stephen Gillies, and Kin-Ming Lo
Laminin Modulates Morphogenic Properties of the Collagen XVIII Endostatin Domain
J. Biol. Chem. 2002 277: 45211-45218. First Published on September 16, 2002; 10.1074/jbc.M206358200 [Abstract] [Full Text] [PDF]  

Jeffrey S. Rush, Steve K. Cho, Songmin Jiang, Sandra L. Hofmann, and Charles J. Waechter
Identification and Characterization of a cDNA Encoding a Dolichyl Pyrophosphate Phosphatase Located in the Endoplasmic Reticulum of Mammalian Cells
J. Biol. Chem. 2002 277: 45226-45234. First Published on August 26, 2002; 10.1074/jbc.M207076200 [Abstract] [Full Text] [PDF]  

Chihiro Sato, Tsukasa Matsuda, and Ken Kitajima
Neuronal Differentiation-dependent Expression of the Disialic Acid Epitope on CD166 and Its Involvement in Neurite Formation in Neuro2A Cells
J. Biol. Chem. 2002 277: 45299-45305. First Published on September 15, 2002; 10.1074/jbc.M206046200 [Abstract] [Full Text] [PDF]  


Lipids and Lipoproteins:

Jin-ichi Ito, Yuko Nagayasu, Sachiko Ueno, and Shinji Yokoyama
Apolipoprotein-mediated Cellular Lipid Release Requires Replenishment of Sphingomyelin in a Phosphatidylcholine-specific Phospholipase C-dependent Manner
J. Biol. Chem. 2002 277: 44709-44714. First Published on September 12, 2002; 10.1074/jbc.M208379200 [Abstract] [Full Text] [PDF]  

Hedia Marrakchi, Keum-Hwa Choi, and Charles O. Rock
A New Mechanism for Anaerobic Unsaturated Fatty Acid Formation in Streptococcus pneumoniae
J. Biol. Chem. 2002 277: 44809-44816. First Published on September 16, 2002; 10.1074/jbc.M208920200 [Abstract] [Full Text] [PDF]  

Kevin R. Kozak, Brenda C. Crews, Jason D. Morrow, Lee-Ho Wang, Y. Henry Ma, Rolf Weinander, Per-Johan Jakobsson, and Lawrence J. Marnett
Metabolism of the Endocannabinoids, 2-Arachidonylglycerol and Anandamide, into Prostaglandin, Thromboxane, and Prostacyclin Glycerol Esters and Ethanolamides
J. Biol. Chem. 2002 277: 44877-44885. First Published on September 19, 2002; 10.1074/jbc.M206788200 [Abstract] [Full Text] [PDF]  

Christopher M. Wiethoff, Michelle L. Gill, Gary S. Koe, Janet G. Koe, and C. Russell Middaugh
The Structural Organization of Cationic Lipid-DNA Complexes
J. Biol. Chem. 2002 277: 44980-44987. First Published on September 23, 2002; 10.1074/jbc.M207758200 [Abstract] [Full Text] [PDF]  


Membrane Transport Structure Function and Biogenesis:

Wei Feng, Jiancheng Tu, Tianzhong Yang, Patty Shih Vernon, Paul D. Allen, Paul F. Worley, and Isaac N. Pessah
Homer Regulates Gain of Ryanodine Receptor Type 1 Channel Complex
J. Biol. Chem. 2002 277: 44722-44730. First Published on September 9, 2002; 10.1074/jbc.M207675200 [Abstract] [Full Text] [PDF]  

Pilar Maria Crespo, Adolfo Ramón Zurita, and Jose Luis Daniotti
Effect of Gangliosides on the Distribution of a Glycosylphosphatidylinositol-anchored Protein in Plasma Membrane from Chinese Hamster Ovary-K1 Cells
J. Biol. Chem. 2002 277: 44731-44739. First Published on September 16, 2002; 10.1074/jbc.M204604200 [Abstract] [Full Text] [PDF]  

A. Russell Tupling, Michio Asahi, and David H. MacLennan
Sarcolipin Overexpression in Rat Slow Twitch Muscle Inhibits Sarcoplasmic Reticulum Ca2+ Uptake and Impairs Contractile Function
J. Biol. Chem. 2002 277: 44740-44746. First Published on September 16, 2002; 10.1074/jbc.M206171200 [Abstract] [Full Text] [PDF]  

Suk-Jo Kang and Peter Cresswell
Calnexin, Calreticulin, and ERp57 Cooperate in Disulfide Bond Formation in Human CD1d Heavy Chain
J. Biol. Chem. 2002 277: 44838-44844. First Published on September 17, 2002; 10.1074/jbc.M207831200 [Abstract] [Full Text] [PDF]  

Qiang Shan, Justine L. Haddrill, and Joseph W. Lynch
Comparative Surface Accessibility of a Pore-lining Threonine Residue (T6') in the Glycine and GABAA Receptors
J. Biol. Chem. 2002 277: 44845-44853. First Published on September 17, 2002; 10.1074/jbc.M208647200 [Abstract] [Full Text] [PDF]  

Patrick E. MacDonald, Sabine Sewing, Jianli Wang, Jamie W. Joseph, Simon R. Smukler, George Sakellaropoulos, Jing Wang, Monique C. Saleh, Catherine B. Chan, Robert G. Tsushima, Anne Marie F. Salapatek, and Michael B. Wheeler
Inhibition of Kv2.1 Voltage-dependent K+ Channels in Pancreatic beta -Cells Enhances Glucose-dependent Insulin Secretion
J. Biol. Chem. 2002 277: 44938-44945. First Published on September 20, 2002; 10.1074/jbc.M205532200 [Abstract] [Full Text] [PDF]  

Erwann Le Rouzic, Aurélie Mousnier, Cecilia Rustum, Françoise Stutz, Einar Hallberg, Catherine Dargemont, and Serge Benichou
Docking of HIV-1 Vpr to the Nuclear Envelope Is Mediated by the Interaction with the Nucleoporin hCG1
J. Biol. Chem. 2002 277: 45091-45098. First Published on September 12, 2002; 10.1074/jbc.M207439200 [Abstract] [Full Text] [PDF]  

Takashi Okuda, Michiko Okamura, China Kaitsuka, Tatsuya Haga, and David Gurwitz
Single Nucleotide Polymorphism of the Human High Affinity Choline Transporter Alters Transport Rate
J. Biol. Chem. 2002 277: 45315-45322. First Published on September 16, 2002; 10.1074/jbc.M207742200 [Abstract] [Full Text] [PDF]  

Sakiko Okumoto, Roberto Schmidt, Mechthild Tegeder, Wolf N. Fischer, Doris Rentsch, Wolf B. Frommer, and Wolfgang Koch
High Affinity Amino Acid Transporters Specifically Expressed in Xylem Parenchyma and Developing Seeds of Arabidopsis
J. Biol. Chem. 2002 277: 45338-45346. First Published on September 18, 2002; 10.1074/jbc.M207730200 [Abstract] [Full Text] [PDF]  

Leonard Dode, Bente Vilsen, Kurt Van Baelen, Frank Wuytack, Johannes D. Clausen, and Jens Peter Andersen
Dissection of the Functional Differences between Sarco(endo)plasmic Reticulum Ca2+-ATPase (SERCA) 1 and 3 Isoforms by Steady-state and Transient Kinetic Analyses
J. Biol. Chem. 2002 277: 45579-45591. First Published on August 30, 2002; 10.1074/jbc.M207778200 [Abstract] [Full Text] [PDF]  

Hiroshi Omote and Marwan K. Al-Shawi
A Novel Electron Paramagnetic Resonance Approach to Determine the Mechanism of Drug Transport by P-glycoprotein
J. Biol. Chem. 2002 277: 45688-45694. First Published on September 19, 2002; 10.1074/jbc.M206479200 [Abstract] [Full Text] [PDF]  

Tapan K. Biswas and Godfrey S. Getz
Import of Yeast Mitochondrial Transcription Factor (Mtf1p) via a Nonconventional Pathway
J. Biol. Chem. 2002 277: 45704-45714. First Published on September 20, 2002; 10.1074/jbc.M202565200 [Abstract] [Full Text] [PDF]  


Mechanisms Of Signal Transduction:

Evgenia V. Gerasimovskaya, Shama Ahmad, Carl W. White, Peter L. Jones, Todd C. Carpenter, and Kurt R. Stenmark
Extracellular ATP Is an Autocrine/Paracrine Regulator of Hypoxia-induced Adventitial Fibroblast Growth. SIGNALING THROUGH EXTRACELLULAR SIGNAL-REGULATED KINASE-1/2 AND THE Egr-1 TRANSCRIPTION FACTOR
J. Biol. Chem. 2002 277: 44638-44650. First Published on September 18, 2002; 10.1074/jbc.M203012200 [Abstract] [Full Text] [PDF]  

Shuichi Saito, Gerald D. Frank, Mizuo Mifune, Motoi Ohba, Hirotoshi Utsunomiya, Evangeline D. Motley, Tadashi Inagami, and Satoru Eguchi
Ligand-independent trans-Activation of the Platelet-derived Growth Factor Receptor by Reactive Oxygen Species Requires Protein Kinase C-delta and c-Src
J. Biol. Chem. 2002 277: 44695-44700. First Published on September 10, 2002; 10.1074/jbc.M208332200 [Abstract] [Full Text] [PDF]  

Su-Ji Han, Hyun-Mi Ko, Jung-Hwa Choi, Kook Heon Seo, Hyun-Suk Lee, Eun-Kyoung Choi, Il-Whan Choi, Hern-Ku Lee, and Suhn-Young Im
Molecular Mechanisms for Lipopolysaccharide-induced Biphasic Activation of Nuclear Factor-kappa B (NF-kappa B)
J. Biol. Chem. 2002 277: 44715-44721. First Published on September 13, 2002; 10.1074/jbc.M202524200 [Abstract] [Full Text] [PDF]  

Bernd Baumann, Frank Bohnenstengel, Daniela Siegmund, Harald Wajant, Christoph Weber, Ingrid Herr, Klaus-Michael Debatin, Peter Proksch, and Thomas Wirth
Rocaglamide Derivatives Are Potent Inhibitors of NF-kappa B Activation in T-cells
J. Biol. Chem. 2002 277: 44791-44800. First Published on September 16, 2002; 10.1074/jbc.M208003200 [Abstract] [Full Text] [PDF]  

Eleanor W. Trotter, Camilla M.-F. Kao, Ludmilla Berenfeld, David Botstein, Gregory A. Petsko, and Joseph V. Gray
Misfolded Proteins Are Competent to Mediate a Subset of the Responses to Heat Shock in Saccharomyces cerevisiae
J. Biol. Chem. 2002 277: 44817-44825. First Published on September 17, 2002; 10.1074/jbc.M204686200 [Abstract] [Full Text] [PDF] Supplemental Data  

Satsuki Mochizuki, Bertrand Brassart, and Aleksander Hinek
Signaling Pathways Transduced through the Elastin Receptor Facilitate Proliferation of Arterial Smooth Muscle Cells
J. Biol. Chem. 2002 277: 44854-44863. First Published on September 18, 2002; 10.1074/jbc.M205630200 [Abstract] [Full Text] [PDF]  

Nobuko Ito, Takehiko Yokomizo, Takehiko Sasaki, Hiroshi Kurosu, Josef Penninger, Yasunori Kanaho, Toshiaki Katada, Kazuo Hanaoka, and Takao Shimizu
Requirement of Phosphatidylinositol 3-Kinase Activation and Calcium Influx for Leukotriene B4-induced Enzyme Release
J. Biol. Chem. 2002 277: 44898-44904. First Published on September 19, 2002; 10.1074/jbc.M208051200 [Abstract] [Full Text] [PDF]  

Seán Shaw, Merouane Bencherif, and Mario B. Marrero
Janus Kinase 2, an Early Target of alpha 7 Nicotinic Acetylcholine Receptor-mediated Neuroprotection against Abeta -(1-42) Amyloid
J. Biol. Chem. 2002 277: 44920-44924. First Published on September 18, 2002; 10.1074/jbc.M204610200 [Abstract] [Full Text] [PDF]  

Jean-François Mercier, Ali Salahpour, Stéphane Angers, Andreas Breit, and Michel Bouvier
Quantitative Assessment of beta 1- and beta 2-Adrenergic Receptor Homo- and Heterodimerization by Bioluminescence Resonance Energy Transfer
J. Biol. Chem. 2002 277: 44925-44931. First Published on September 19, 2002; 10.1074/jbc.M205767200 [Abstract] [Full Text] [PDF]  

Suwan K. Sinha, Sunny Zachariah, Herson I. Quiñones, Masahisa Shindo, and Preet M. Chaudhary
Role of TRAF3 and -6 in the Activation of the NF-kappa B and JNK Pathways by X-linked Ectodermal Dysplasia Receptor
J. Biol. Chem. 2002 277: 44953-44961. First Published on September 20, 2002; 10.1074/jbc.M207923200 [Abstract] [Full Text] [PDF]  

Cai Bowen, Michael Birrer, and Edward P. Gelmann
Retinoblastoma Protein-mediated Apoptosis After gamma -Irradiation
J. Biol. Chem. 2002 277: 44969-44979. First Published on September 23, 2002; 10.1074/jbc.M202000200 [Abstract] [Full Text] [PDF]  

Amit Verma, Mani Mohindru, Dilip K. Deb, Antonella Sassano, Suman Kambhampati, Farhad Ravandi, Saverio Minucci, Dhananjaya V. Kalvakolanu, and Leonidas C. Platanias
Activation of Rac1 and the p38 Mitogen-activated Protein Kinase Pathway in Response to Arsenic Trioxide
J. Biol. Chem. 2002 277: 44988-44995. First Published on September 17, 2002; 10.1074/jbc.M207176200 [Abstract] [Full Text] [PDF]  

Xiaoqin Xiang, Mengwei Zang, Christine A. Waelde, Rong Wen, and Zhijun Luo
Phosphorylation of 338SSYY341 Regulates Specific Interaction between Raf-1 and MEK1
J. Biol. Chem. 2002 277: 44996-45003. First Published on September 19, 2002; 10.1074/jbc.M203953200 [Abstract] [Full Text] [PDF]  

Sheu-Fen Lee, Sanjiv Shah, Hongqiao Li, Cong Yu, Weiping Han, and Gang Yu
Mammalian APH-1 Interacts with Presenilin and Nicastrin and Is Required for Intramembrane Proteolysis of Amyloid-beta Precursor Protein and Notch
J. Biol. Chem. 2002 277: 45013-45019. First Published on September 23, 2002; 10.1074/jbc.M208164200 [Abstract] [Full Text] [PDF]  

Ning Gao, Bing-Hua Jiang, Stephen S. Leonard, Linda Corum, Zhuo Zhang, Jenny R. Roberts, Jim Antonini, Jenny Z. Zheng, Daniel C. Flynn, Vince Castranova, and Xianglin Shi
p38 Signaling-mediated Hypoxia-inducible Factor 1alpha and Vascular Endothelial Growth Factor Induction by Cr(VI) in DU145 Human Prostate Carcinoma Cells
J. Biol. Chem. 2002 277: 45041-45048. First Published on September 3, 2002; 10.1074/jbc.M202775200 [Abstract] [Full Text] [PDF]  

Tianbao Yang and B. W. Poovaiah
A Calmodulin-binding/CGCG Box DNA-binding Protein Family Involved in Multiple Signaling Pathways in Plants
J. Biol. Chem. 2002 277: 45049-45058. First Published on September 5, 2002; 10.1074/jbc.M207941200 [Abstract] [Full Text] [PDF] Supplemental Data  

Giles O. C. Cory, Ritu Garg, Rainer Cramer, and Anne J. Ridley
Phosphorylation of Tyrosine 291 Enhances the Ability of WASp to Stimulate Actin Polymerization and Filopodium Formation
J. Biol. Chem. 2002 277: 45115-45121. First Published on September 15, 2002; 10.1074/jbc.M203346200 [Abstract] [Full Text] [PDF]  

Thilo Mokros, Armin Rehm, Jana Droese, Martin Oppermann, Martin Lipp, and Uta E. Höpken
Surface Expression and Endocytosis of the Human Cytomegalovirus-encoded Chemokine Receptor US28 Is Regulated by Agonist-independent Phosphorylation
J. Biol. Chem. 2002 277: 45122-45128. First Published on September 18, 2002; 10.1074/jbc.M208214200 [Abstract] [Full Text] [PDF]  

Xiang Li, Paul E. Massa, Adedayo Hanidu, Gregory W. Peet, Patrick Aro, Ann Savitt, Sheenah Mische, Jun Li, and Kenneth B. Marcu
IKKalpha , IKKbeta , and NEMO/IKKgamma Are Each Required for the NF-kappa B-mediated Inflammatory Response Program
J. Biol. Chem. 2002 277: 45129-45140. First Published on September 6, 2002; 10.1074/jbc.M205165200 [Abstract] [Full Text] [PDF]  

Olivier Micheau, Margot Thome, Pascal Schneider, Nils Holler, Jürg Tschopp, Donald W. Nicholson, Christophe Briand, and Markus G. Grütter
The Long Form of FLIP Is an Activator of Caspase-8 at the Fas Death-inducing Signaling Complex
J. Biol. Chem. 2002 277: 45162-45171. First Published on September 4, 2002; 10.1074/jbc.M206882200 [Abstract] [Full Text] [PDF]  

Patrick J. Leavey, Carolina Gonzalez-Aller, Gail Thurman, Michael Kleinberg, Lori Rinckel, Daniel W. Ambruso, Stefanie Freeman, Frans A. Kuypers, and Daniel R. Ambruso
A 29-kDa Protein Associated with p67phox Expresses Both Peroxiredoxin and Phospholipase A2 Activity and Enhances Superoxide Anion Production by a Cell-free System of NADPH Oxidase Activity
J. Biol. Chem. 2002 277: 45181-45187. First Published on November 15, 2002; 10.1074/jbc.M202869200 [Abstract] [Full Text] [PDF]  

Jaime Melendez, Sara Welch, Erik Schaefer, Christine S. Moravec, Shalom Avraham, Hava Avraham, and Mark A. Sussman
Activation of pyk2/Related Focal Adhesion Tyrosine Kinase and Focal Adhesion Kinase in Cardiac Remodeling
J. Biol. Chem. 2002 277: 45203-45210. First Published on September 12, 2002; 10.1074/jbc.M204886200 [Abstract] [Full Text] [PDF]  

Sang Gyu Park, Young-Sun Kang, Young Ha Ahn, Soon Hee Lee, Kwang-Rok Kim, Kyu-Won Kim, Gou Young Koh, Young-Gyu Ko, and Sunghoon Kim
Dose-dependent Biphasic Activity of tRNA Synthetase-associating Factor, p43, in Angiogenesis
J. Biol. Chem. 2002 277: 45243-45248. First Published on September 16, 2002; 10.1074/jbc.M207934200 [Abstract] [Full Text] [PDF]  

Brian Park, Nhan T. Nguyen, Parmesh Dutt, Keith D. Merdek, Mariam Bashar, Paola Sterpetti, Alessandra Tosolini, Joseph R. Testa, and Deniz Toksoz
Association of Lbc Rho Guanine Nucleotide Exchange Factor with alpha -Catenin-related Protein, alpha -Catulin/CTNNAL1, Supports Serum Response Factor Activation
J. Biol. Chem. 2002 277: 45361-45370. First Published on September 20, 2002; 10.1074/jbc.M202447200 [Abstract] [Full Text] [PDF]  

José L. Zugaza, Miguel A. López-Lago, María J. Caloca, Mercedes Dosil, Nieves Movilla, and Xosé R. Bustelo
Structural Determinants for the Biological Activity of Vav Proteins
J. Biol. Chem. 2002 277: 45377-45392. First Published on September 12, 2002; 10.1074/jbc.M208039200 [Abstract] [Full Text] [PDF]  

Feng Liu, David M. Virshup, Angus C. Nairn, and Paul Greengard
Mechanism of Regulation of Casein Kinase I Activity by Group I Metabotropic Glutamate Receptors
J. Biol. Chem. 2002 277: 45393-45399. First Published on September 9, 2002; 10.1074/jbc.M204499200 [Abstract] [Full Text] [PDF]  

Hirotada Fujita, Hironori Katoh, Yukio Ishikawa, Kazutoshi Mori, and Manabu Negishi
Rapostlin Is a Novel Effector of Rnd2 GTPase Inducing Neurite Branching
J. Biol. Chem. 2002 277: 45428-45434. First Published on September 18, 2002; 10.1074/jbc.M208090200 [Abstract] [Full Text] [PDF]  

Ilona Brändlin, Tim Eiseler, Rüdiger Salowsky, and Franz-Josef Johannes
Protein Kinase Cµ Regulation of the JNK Pathway Is Triggered via Phosphoinositide-dependent Kinase 1 and Protein Kinase Cepsilon
J. Biol. Chem. 2002 277: 45451-45457. First Published on September 9, 2002; 10.1074/jbc.M205299200 [Abstract] [Full Text] [PDF]  

Katsuhiko Sakurada, Hirotsugu Kato, Hiromitsu Nagumo, Hideji Hiraoka, Kaoru Furuya, Toshihiko Ikuhara, Yoshihiko Yamakita, Kouji Fukunaga, Eishichi Miyamoto, Fumio Matsumura, Yuri-Ikeda Matsuo, Yasuhito Naito, and Yasuharu Sasaki
Synapsin I Is Phosphorylated at Ser603 by p21-activated Kinases (PAKs) in Vitro and in PC12 Cells Stimulated with Bradykinin
J. Biol. Chem. 2002 277: 45473-45479. First Published on September 16, 2002; 10.1074/jbc.M206673200 [Abstract] [Full Text] [PDF]  

Hirofumi Jono, Tsuyoshi Shuto, Haidong Xu, Hirofumi Kai, David J. Lim, James R. Gum, Jr., Young S. Kim, Shoji Yamaoka, Xin-Hua Feng, and Jian-Dong Li
Transforming Growth Factor-beta -Smad Signaling Pathway Cooperates with NF-kappa B to Mediate Nontypeable Haemophilus influenzae-induced MUC2 Mucin Transcription
J. Biol. Chem. 2002 277: 45547-45557. First Published on September 16, 2002; 10.1074/jbc.M206883200 [Abstract] [Full Text] [PDF]  

Reiko Adachi, Kosei Takeuchi, and Kazuhiro Suzuki
Antisense Oligonucleotide to Cofilin Enhances Respiratory Burst and Phagocytosis in Opsonized Zymosan-stimulated Mouse Macrophage J774.1 Cells
J. Biol. Chem. 2002 277: 45566-45571. First Published on September 23, 2002; 10.1074/jbc.M207419200 [Abstract] [Full Text] [PDF]  

Tao Zhu, Ling Ling, and Peter E. Lobie
Identification of a JAK2-independent Pathway Regulating Growth Hormone (GH)-stimulated p44/42 Mitogen-activated Protein Kinase Activity. GH ACTIVATION OF Ral AND PHOSPHOLIPASE D IS Src-DEPENDENT
J. Biol. Chem. 2002 277: 45592-45603. First Published on September 5, 2002; 10.1074/jbc.M201385200 [Abstract] [Full Text] [PDF]  

Hui-Fang Cheng and Raymond C. Harris
Cyclooxygenase-2 Expression in Cultured Cortical Thick Ascending Limb of Henle Increases in Response to Decreased Extracellular Ionic Content by Both Transcriptional and Post-transcriptional Mechanisms. ROLE OF p38-MEDIATED PATHWAYS
J. Biol. Chem. 2002 277: 45638-45643. First Published on September 16, 2002; 10.1074/jbc.M206040200 [Abstract] [Full Text] [PDF]  

Jill M. Dunty and Michael D. Schaller
The N Termini of Focal Adhesion Kinase Family Members Regulate Substrate Phosphorylation, Localization, and Cell Morphology
J. Biol. Chem. 2002 277: 45644-45654. First Published on September 9, 2002; 10.1074/jbc.M201779200 [Abstract] [Full Text] [PDF]  

Dong Cho Han, Tang-Long Shen, Hui Miao, Bingcheng Wang, and Jun-Lin Guan
EphB1 Associates with Grb7 and Regulates Cell Migration
J. Biol. Chem. 2002 277: 45655-45661. First Published on September 9, 2002; 10.1074/jbc.M203165200 [Abstract] [Full Text] [PDF]  

Mehul Shah, Kirit Patel, Victor A. Fried, and Pravin B. Sehgal
Interactions of STAT3 with Caveolin-1 and Heat Shock Protein 90 in Plasma Membrane Raft and Cytosolic Complexes. PRESERVATION OF CYTOKINE SIGNALING DURING FEVER
J. Biol. Chem. 2002 277: 45662-45669. First Published on September 13, 2002; 10.1074/jbc.M205935200 [Abstract] [Full Text] [PDF]  

Steven J. Schreiner, Anthony P. Schiavone, and Thomas E. Smithgall
Activation of STAT3 by the Src Family Kinase Hck Requires a Functional SH3 Domain
J. Biol. Chem. 2002 277: 45680-45687. First Published on September 19, 2002; 10.1074/jbc.M204255200 [Abstract] [Full Text] [PDF]  

Maria Obrero, David V. Yu, and David J. Shapiro
Estrogen Receptor-dependent and Estrogen Receptor-independent Pathways for Tamoxifen and 4-Hydroxytamoxifen-induced Programmed Cell Death
J. Biol. Chem. 2002 277: 45695-45703. First Published on September 19, 2002; 10.1074/jbc.M208092200 [Abstract] [Full Text] [PDF]  


Molecular Basis Of Cell and Developmental Biology:

Maria Elena Torres-Padilla, Frances M. Sladek, and Mary C. Weiss
Developmentally Regulated N-terminal Variants of the Nuclear Receptor Hepatocyte Nuclear Factor 4alpha Mediate Multiple Interactions through Coactivator and Corepressor-Histone Deacetylase Complexes
J. Biol. Chem. 2002 277: 44677-44687. First Published on August 29, 2002; 10.1074/jbc.M207545200 [Abstract] [Full Text] [PDF]  

Elisavet Koutzamani, Helena Loborg, Bettina Sarg, Herbert H. Lindner, and Ingemar Rundquist
Linker Histone Subtype Composition and Affinity for Chromatin in Situ in Nucleated Mature Erythrocytes
J. Biol. Chem. 2002 277: 44688-44694. First Published on September 9, 2002; 10.1074/jbc.M203533200 [Abstract] [Full Text] [PDF]  

Ling Song, Patrizia De Sarno, and Richard S. Jope
Central Role of Glycogen Synthase Kinase-3beta in Endoplasmic Reticulum Stress-induced Caspase-3 Activation
J. Biol. Chem. 2002 277: 44701-44708. First Published on September 12, 2002; 10.1074/jbc.M206047200 [Abstract] [Full Text] [PDF]  

Matthew G. Vander Heiden, John S. Choy, David J. VanderWeele, Jennifer L. Brace, Marian H. Harris, Daniel E. Bauer, Bryan Prange, Stephen J. Kron, Craig B. Thompson, and Charles M. Rudin
Bcl-xL Complements Saccharomyces cerevisiae Genes That Facilitate the Switch from Glycolytic to Oxidative Metabolism
J. Biol. Chem. 2002 277: 44870-44876. First Published on September 19, 2002; 10.1074/jbc.M204888200 [Abstract] [Full Text] [PDF]  

Cynthia D. Cooper and Paul D. Lampe
Casein Kinase 1 Regulates Connexin-43 Gap Junction Assembly
J. Biol. Chem. 2002 277: 44962-44968. First Published on September 20, 2002; 10.1074/jbc.M209427200 [Abstract] [Full Text] [PDF]  

Kevin J. Bitterman, Rozalyn M. Anderson, Haim Y. Cohen, Magda Latorre-Esteves, and David A. Sinclair
Inhibition of Silencing and Accelerated Aging by Nicotinamide, a Putative Negative Regulator of Yeast Sir2 and Human SIRT1
J. Biol. Chem. 2002 277: 45099-45107. First Published on September 23, 2002; 10.1074/jbc.M205670200 [Abstract] [Full Text] [PDF]  

David L. Allen and Leslie A. Leinwand
Intracellular Calcium and Myosin Isoform Transitions. CALCINEURIN AND CALCIUM-CALMODULIN KINASE PATHWAYS REGULATE PREFERENTIAL ACTIVATION OF THE IIa MYOSIN HEAVY CHAIN PROMOTER
J. Biol. Chem. 2002 277: 45323-45330. First Published on September 15, 2002; 10.1074/jbc.M208302200 [Abstract] [Full Text] [PDF]  

Alexandra Lerch-Gaggl, Jamil Haque, Jixuan Li, Gang Ning, Paula Traktman, and Stephen A. Duncan
Pescadillo Is Essential for Nucleolar Assembly, Ribosome Biogenesis, and Mammalian Cell Proliferation
J. Biol. Chem. 2002 277: 45347-45355. First Published on September 16, 2002; 10.1074/jbc.M208338200 [Abstract] [Full Text] [PDF]  

Shao-Qing Kuang, Lan Liao, Hao Zhang, Fred A. Pereira, Yuhui Yuan, Francesco J. DeMayo, Lan Ko, and Jianming Xu
Deletion of the Cancer-amplified Coactivator AIB3 Results in Defective Placentation and Embryonic Lethality
J. Biol. Chem. 2002 277: 45356-45360. First Published on October 3, 2002; 10.1074/jbc.C200509200 [Abstract] [Full Text] [PDF]  

Marc D. H. Hansen, Jason S. Ehrlich, and W. James Nelson
Molecular Mechanism for Orienting Membrane and Actin Dynamics to Nascent Cell-Cell Contacts in Epithelial Cells
J. Biol. Chem. 2002 277: 45371-45376. First Published on September 18, 2002; 10.1074/jbc.M207747200 [Abstract] [Full Text] [PDF]  

William F. Holmes, Dianne Robert Soprano, and Kenneth J. Soprano
Elucidation of Molecular Events Mediating Induction of Apoptosis by Synthetic Retinoids Using a CD437-resistant Ovarian Carcinoma Cell Line
J. Biol. Chem. 2002 277: 45408-45419. First Published on September 16, 2002; 10.1074/jbc.M204600200 [Abstract] [Full Text] [PDF]  

Maísa I. García Arguinzonis, Annette B. Galler, Ulrich Walter, Matthias Reinhard, and Andreas Simm
Increased Spreading, Rac/p21-activated Kinase (PAK) Activity, and Compromised Cell Motility in Cells Deficient in Vasodilator-stimulated Phosphoprotein (VASP)
J. Biol. Chem. 2002 277: 45604-45610. First Published on June 7, 2002; 10.1074/jbc.M202873200 [Abstract] [Full Text] [PDF]  


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Copyright © 2002 by the American Society for Biochemistry and Molecular Biology.