JBC -- Table of Contents (Mar 7 2003, 278, (10))

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DNA: Replication, Repair, and Recombination:

George J. Klarmann, Xin Chen, Thomas W. North, and Bradley D. Preston: Incorporation of Uracil into Minus Strand DNA Affects the Specificity of Plus Strand Synthesis Initiation during Lentiviral Reverse Transcription
J. Biol. Chem. 2003 278: 7902-7909. First Published on November 27, 2002; doi:10.1074/jbc.M207223200 [Abstract] [Full Text] [PDF]

Joseph J. Rasimas, Anthony E. Pegg, and Michael G. Fried: DNA-binding Mechanism of O⁶-Alkylguanine-DNA Alkyltransferase. EFFECTS OF PROTEIN AND DNA ALKYLATION ON COMPLEX STABILITY
J. Biol. Chem. 2003 278: 7973-7980. First Published on December 20, 2002; doi:10.1074/jbc.M211854200 [Abstract] [Full Text] [PDF]

Yan Chen, Mini Balakrishnan, Bernard P. Roques, Philip J. Fay, and Robert A. Bambara: Mechanism of Minus Strand Strong Stop Transfer in HIV-1 Reverse Transcription
J. Biol. Chem. 2003 278: 8006-8017. First Published on December 23, 2002; doi:10.1074/jbc.M210959200 [Abstract] [Full Text] [PDF]

Vladimir O. Kolosha and Sandra L. Martin: High-affinity, Non-sequence-specific RNA Binding by the Open Reading Frame 1 (ORF1) Protein from Long Interspersed Nuclear Element 1 (LINE-1)
J. Biol. Chem. 2003 278: 8112-8117. First Published on December 27, 2002; doi:10.1074/jbc.M210487200 [Abstract] [Full Text] [PDF]

Corey D. Braastad, Zhiyong Han, and Eric A. Hendrickson: Constitutive DNase I Hypersensitivity of p53-Regulated Promoters
J. Biol. Chem. 2003 278: 8261-8268. First Published on December 9, 2002; doi:10.1074/jbc.M204256200 [Abstract] [Full Text] [PDF]

Lyuben Tsvetkov, Xingzhi Xu, Jia Li, and David F. Stern: Polo-like Kinase 1 and Chk2 Interact and Co-localize to Centrosomes and the Midbody
J. Biol. Chem. 2003 278: 8468-8475. First Published on December 18, 2002; doi:10.1074/jbc.M211202200 [Abstract] [Full Text] [PDF]

Pearl Nurse, Cindy Levine, Heide Hassing, and Kenneth J. Marians: Topoisomerase III Can Serve as the Cellular Decatenase in Escherichia coli
J. Biol. Chem. 2003 278: 8653-8660. First Published on December 31, 2002; doi:10.1074/jbc.M211211200 [Abstract] [Full Text] [PDF]

Mika Abu and Timothy R. Waters: The Main Role of Human Thymine-DNA Glycosylase Is Removal of Thymine Produced by Deamination of 5-Methylcytosine and Not Removal of Ethenocytosine
J. Biol. Chem. 2003 278: 8739-8744. First Published on December 18, 2002; doi:10.1074/jbc.M211084200 [Abstract] [Full Text] [PDF]

Xingzhi Xu and David F. Stern: NFBD1/KIAA0170 Is a Chromatin-associated Protein Involved in DNA Damage Signaling Pathways
J. Biol. Chem. 2003 278: 8795-8803. First Published on December 23, 2002; doi:10.1074/jbc.M211392200 [Abstract] [Full Text] [PDF]

Hiroshi Hiasa, Molly E. Shea, Christine M. Richardson, and Michael N. Gwynn: Staphylococcus aureus Gyrase-Quinolone-DNA Ternary Complexes Fail to Arrest Replication Fork Progression in Vitro. EFFECTS OF SALT ON THE DNA BINDING MODE AND THE CATALYTIC ACTIVITY OF S. AUREUS GYRASE
J. Biol. Chem. 2003 278: 8861-8868. First Published on December 23, 2002; doi:10.1074/jbc.M209207200 [Abstract] [Full Text] [PDF]

Genes: Structure and Regulation:

Alexander M. Erkine and David S. Gross: Dynamic Chromatin Alterations Triggered by Natural and Synthetic Activation Domains
J. Biol. Chem. 2003 278: 7755-7764. First Published on December 23, 2002; doi:10.1074/jbc.M211703200 [Abstract] [Full Text] [PDF]

Loretta Jackson-Hayes, Shulan Song, Eduard N. Lavrentyev, Michelle S. Jansen, F. Bradley Hillgartner, Liquin Tian, Philip A. Wood, George A. Cook, and Edwards A. Park: A Thyroid Hormone Response Unit Formed between the Promoter and First Intron of the Carnitine Palmitoyltransferase-I $alpha$ Gene Mediates the Liver-specific Induction by Thyroid Hormone
J. Biol. Chem. 2003 278: 7964-7972. First Published on December 19, 2002; doi:10.1074/jbc.M211062200 [Abstract] [Full Text] [PDF]

Mi-Kyoung Kwak, Nobunao Wakabayashi, Ken Itoh, Hozumi Motohashi, Masayuki Yamamoto, and Thomas W. Kensler: Modulation of Gene Expression by Cancer Chemopreventive Dithiolethiones through the Keap1-Nrf2 Pathway. IDENTIFICATION OF NOVEL GENE CLUSTERS FOR CELL SURVIVAL
J. Biol. Chem. 2003 278: 8135-8145. First Published on December 27, 2002; doi:10.1074/jbc.M211898200 [Abstract] [Full Text] [PDF]

Yoshiaki Onishi and Ryoiti Kiyama: Interaction of NF-E2 in the Human $beta$ -Globin Locus Control Region before Chromatin Remodeling
J. Biol. Chem. 2003 278: 8163-8171. First Published on December 30, 2002; doi:10.1074/jbc.M209612200 [Abstract] [Full Text] [PDF]

Georgia Schäfer, Thorsten Cramer, Guntram Suske, Wolfgang Kemmner, Bertram Wiedenmann, and Michael Höcker: Oxidative Stress Regulates Vascular Endothelial Growth Factor-A Gene Transcription through Sp1- and Sp3-dependent Activation of Two Proximal GC-rich Promoter Elements
J. Biol. Chem. 2003 278: 8190-8198. First Published on December 30, 2002; doi:10.1074/jbc.M211999200 [Abstract] [Full Text] [PDF]

Leen Callewaert, Guy Verrijdt, Valerie Christiaens, Annemie Haelens, and Frank Claessens: Dual Function of an Amino-terminal Amphipatic Helix in Androgen Receptor-mediated Transactivation through Specific and Nonspecific Response Elements
J. Biol. Chem. 2003 278: 8212-8218. First Published on December 31, 2002; doi:10.1074/jbc.M210744200 [Abstract] [Full Text] [PDF]

Janelle B. Barry, Gary M. Leong, W. Bret Church, Laura L. Issa, John A. Eisman, and Edith M. Gardiner: Interactions of SKIP/NCoA-62, TFIIB, and Retinoid X Receptor with Vitamin D Receptor Helix H10 Residues
J. Biol. Chem. 2003 278: 8224-8228. First Published on January 15, 2003; doi:10.1074/jbc.C200712200 [Abstract] [Full Text] [PDF]

Yiwen Peng and Nadia Jahroudi: The NFY Transcription Factor Inhibits von Willebrand Factor Promoter Activation in Non-endothelial Cells through Recruitment of Histone Deacetylases
J. Biol. Chem. 2003 278: 8385-8394. First Published on January 2, 2003; doi:10.1074/jbc.M213156200 [Abstract] [Full Text] [PDF]

Nathan K. Karpowich, Hector H. Huang, Paul C. Smith, and John F. Hunt: Crystal Structures of the BtuF Periplasmic-binding Protein for Vitamin B12 Suggest a Functionally Important Reduction in Protein Mobility upon Ligand Binding
J. Biol. Chem. 2003 278: 8429-8434. First Published on December 4, 2002; doi:10.1074/jbc.M212239200 [Abstract] [Full Text] [PDF]

Michael D. Wheeler and Ronald G. Thurman: Up-regulation of CD14 in Liver Caused by Acute Ethanol Involves Oxidant-dependent AP-1 Pathway
J. Biol. Chem. 2003 278: 8435-8441. First Published on December 13, 2002; doi:10.1074/jbc.M212076200 [Abstract] [Full Text] [PDF]

Toshiharu Ubukata, Tomoko Shimizu, Nobuaki Adachi, Kazuhisa Sekimizu, and Toshiyuki Nakanishi: Cleavage, but Not Read-through, Stimulation Activity Is Responsible for Three Biologic Functions of Transcription Elongation Factor S-II
J. Biol. Chem. 2003 278: 8580-8585. First Published on December 20, 2002; doi:10.1074/jbc.M211384200 [Abstract] [Full Text] [PDF]

Yifei Wu, William W. Chin, Yong Wang, and Thomas P. Burris: Ligand and Coactivator Identity Determines the Requirement of the Charge Clamp for Coactivation of the Peroxisome Proliferator-activated Receptor $gamma$
J. Biol. Chem. 2003 278: 8637-8644. First Published on December 26, 2002; doi:10.1074/jbc.M210910200 [Abstract] [Full Text] [PDF]

Gregory A. Michelotti, Monica J. Bauman, Michael P. Smith, and Debra A. Schwinn: Cloning and Characterization of the Rat $alpha$ _1a-Adrenergic Receptor Gene Promoter. DEMONSTRATION OF CELL SPECIFICITY AND REGULATION BY HYPOXIA
J. Biol. Chem. 2003 278: 8693-8705. First Published on December 5, 2002; doi:10.1074/jbc.M211986200 [Abstract] [Full Text] [PDF]

Chun Fan, Mugen Liu, and Qing Wang: Functional Analysis of TBX5 Missense Mutations Associated with Holt-Oram Syndrome
J. Biol. Chem. 2003 278: 8780-8785. First Published on December 23, 2002; doi:10.1074/jbc.M208120200 [Abstract] [Full Text] [PDF]

Protein Synthesis, Post-Translation Modification, and Degradation:

Yoshinori Shirafuji, Hiroki Tanabe, Donald P. Satchell, Agnes Henschen-Edman, Carole L. Wilson, and Andre J. Ouellette: Structural Determinants of Procryptdin Recognition and Cleavage by Matrix Metalloproteinase-7
J. Biol. Chem. 2003 278: 7910-7919. First Published on December 13, 2002; doi:10.1074/jbc.M210600200 [Abstract] [Full Text] [PDF]

Dmitri V. Rozanov and Alex Y. Strongin: Membrane Type-1 Matrix Metalloproteinase Functions as a Proprotein Self-convertase. EXPRESSION OF THE LATENT ZYMOGEN IN PICHIA PASTORIS, AUTOLYTIC ACTIVATION, AND THE PEPTIDE SEQUENCE OF THE CLEAVAGE FORMS
J. Biol. Chem. 2003 278: 8257-8260. First Published on January 3, 2003; doi:10.1074/jbc.M213246200 [Abstract] [Full Text] [PDF]

Genomics, Proteomics, and Bioinformatics:

Qiang Wang, Kathryn Hobbs, Bert Lynn, and Brian C. Rymond: The Clf1p Splicing Factor Promotes Spliceosome Assembly through N-terminal Tetratricopeptide Repeat Contacts
J. Biol. Chem. 2003 278: 7875-7883. First Published on December 31, 2002; doi:10.1074/jbc.M210839200 [Abstract] [Full Text] [PDF]

Assen Roguev, Daniel Schaft, Anna Shevchenko, Rein Aasland, Andrej Shevchenko, and A. Francis Stewart: High Conservation of the Set1/Rad6 Axis of Histone 3 Lysine 4 Methylation in Budding and Fission Yeasts
J. Biol. Chem. 2003 278: 8487-8493. First Published on December 17, 2002; doi:10.1074/jbc.M209562200 [Abstract] [Full Text] [PDF]

Zhiru Yang, Alexei Savchenko, Alexander Yakunin, Rongguang Zhang, Aled Edwards, Cheryl Arrowsmith, and Liang Tong: Aspartate Dehydrogenase, a Novel Enzyme Identified from Structural and Functional Studies of TM1643
J. Biol. Chem. 2003 278: 8804-8808. First Published on December 21, 2002; doi:10.1074/jbc.M211892200 [Abstract] [Full Text] [PDF]

Zhen Yan, Sangdun Choi, Xuebin Liu, Mei Zhang, Jeoffrey J. Schageman, Sun Young Lee, Rebecca Hart, Ling Lin, Frederick A. Thurmond, and R. Sanders Williams: Highly Coordinated Gene Regulation in Mouse Skeletal Muscle Regeneration
J. Biol. Chem. 2003 278: 8826-8836. First Published on December 10, 2002; doi:10.1074/jbc.M209879200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Protein Structure and Folding:

Xiaotang Wang, Hiroyasu Tachikawa, Xianwen Yi, Kelath M. Manoj, and Lowell P. Hager: Two-dimensional NMR Study of the Heme Active Site Structure of Chloroperoxidase
J. Biol. Chem. 2003 278: 7765-7774. First Published on December 16, 2002; doi:10.1074/jbc.M209462200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Latesh Lad, David J. Schuller, Hideaki Shimizu, Jonathan Friedman, Huiying Li, Paul R. Ortiz de Montellano, and Thomas L. Poulos: Comparison of the Heme-free and -bound Crystal Structures of Human Heme Oxygenase-1
J. Biol. Chem. 2003 278: 7834-7843. First Published on December 24, 2002; doi:10.1074/jbc.M211450200 [Abstract] [Full Text] [PDF]

Salvino D'Amico, Jean-Claude Marx, Charles Gerday, and Georges Feller: Activity-Stability Relationships in Extremophilic Enzymes
J. Biol. Chem. 2003 278: 7891-7896. First Published on January 2, 2003; doi:10.1074/jbc.M212508200 [Abstract] [Full Text] [PDF]

Aysar Aktimur, Melanie A. Gabriel, David Gailani, and John R. Toomey: The Factor IX $gamma$ -Carboxyglutamic Acid (Gla) Domain Is Involved in Interactions between Factor IX and Factor XIa
J. Biol. Chem. 2003 278: 7981-7987. First Published on December 20, 2002; doi:10.1074/jbc.M212748200 [Abstract] [Full Text] [PDF]

Arto Tapio Pulliainen, Sauli Haataja, Sanni Kähkönen, and Jukka Finne: Molecular Basis of H₂O₂ Resistance Mediated by Streptococcal Dpr. DEMONSTRATION OF THE FUNCTIONAL INVOLVEMENT OF THE PUTATIVE FERROXIDASE CENTER BY SITE-DIRECTED MUTAGENESIS IN STREPTOCOCCUS SUIS
J. Biol. Chem. 2003 278: 7996-8005. First Published on December 24, 2002; doi:10.1074/jbc.M210174200 [Abstract] [Full Text] [PDF]

Antonio Garofalo, Marie-Claire Rowlinson, Ngwa A. Amambua, Jacqueline M. Hughes, Sharon M. Kelly, Nicholas C. Price, Alan Cooper, David G. Watson, Malcolm W. Kennedy, and Janette E. Bradley: The FAR Protein Family of the Nematode Caenorhabditis elegans. DIFFERENTIAL LIPID BINDING PROPERTIES, STRUCTURAL CHARACTERISTICS, AND DEVELOPMENTAL REGULATION
J. Biol. Chem. 2003 278: 8065-8074. First Published on December 26, 2002; doi:10.1074/jbc.M206278200 [Abstract] [Full Text] [PDF]

Maria José Hijarrubia, Jesús F. Aparicio, and Juan F. Martín: Domain Structure Characterization of the Multifunctional $alpha$ -Aminoadipate Reductase from Penicillium chrysogenum by Limited Proteolysis. ACTIVATION OF $alpha$ -AMINOADIPATE DOES NOT REQUIRE THE PEPTIDYL CARRIER PROTEIN BOX OR THE REDUCTION DOMAIN
J. Biol. Chem. 2003 278: 8250-8256. First Published on December 31, 2002; doi:10.1074/jbc.M211235200 [Abstract] [Full Text] [PDF]

Yoonsang Cho, Vivek Sharma, and James C. Sacchettini: Crystal Structure of ATP Phosphoribosyltransferase from Mycobacterium tuberculosis
J. Biol. Chem. 2003 278: 8333-8339. First Published on January 2, 2003; doi:10.1074/jbc.M212124200 [Abstract] [Full Text] [PDF]

Pari Malherbe, Nicole Kratochwil, Frédéric Knoflach, Marie-Thérèse Zenner, James N. C. Kew, Claudia Kratzeisen, Hans P. Maerki, Geo Adam, and Vincent Mutel: Mutational Analysis and Molecular Modeling of the Allosteric Binding Site of a Novel, Selective, Noncompetitive Antagonist of the Metabotropic Glutamate 1 Receptor
J. Biol. Chem. 2003 278: 8340-8347. First Published on December 30, 2002; doi:10.1074/jbc.M211759200 [Abstract] [Full Text] [PDF]

Stephen B. Harvey, Matthew D. Stone, Michael B. Martinez, and Gary L. Nelsestuen: Mutagenesis of the $gamma$ -Carboxyglutamic Acid Domain of Human Factor VII to Generate Maximum Enhancement of the Membrane Contact Site
J. Biol. Chem. 2003 278: 8363-8369. First Published on December 27, 2002; doi:10.1074/jbc.M211629200 [Abstract] [Full Text] [PDF]

José Fernando Díaz, Isabel Barasoain, and José Manuel Andreu: Fast Kinetics of Taxol Binding to Microtubules. EFFECTS OF SOLUTION VARIABLES AND MICROTUBULE-ASSOCIATED PROTEINS
J. Biol. Chem. 2003 278: 8407-8419. First Published on December 20, 2002; doi:10.1074/jbc.M211163200 [Abstract] [Full Text] [PDF]

Andrea Haker, Johnny Hendriks, Ivo H. M. van Stokkum, Joachim Heberle, Klaas J. Hellingwerf, Wim Crielaard, and Thomas Gensch: The Two Photocycles of Photoactive Yellow Protein from Rhodobacter sphaeroides
J. Biol. Chem. 2003 278: 8442-8451. First Published on December 20, 2002; doi:10.1074/jbc.M209343200 [Abstract] [Full Text] [PDF]

Eric Merithew, Craig Stone, Sudharshan Eathiraj, and David G. Lambright: Determinants of Rab5 Interaction with the N Terminus of Early Endosome Antigen 1
J. Biol. Chem. 2003 278: 8494-8500. First Published on December 19, 2002; doi:10.1074/jbc.M211514200 [Abstract] [Full Text] [PDF]

Young Jun Im, Seong Ho Park, Seong-Hwan Rho, Jun Hyuck Lee, Gil Bu Kang, Morgan Sheng, Eunjoon Kim, and Soo Hyun Eom: Crystal Structure of GRIP1 PDZ6-Peptide Complex Reveals the Structural Basis for Class II PDZ Target Recognition and PDZ Domain-mediated Multimerization
J. Biol. Chem. 2003 278: 8501-8507. First Published on December 18, 2002; doi:10.1074/jbc.M212263200 [Abstract] [Full Text] [PDF]

K. Johan Rosengren, Norelle L. Daly, Manuel R. Plan, Clement Waine, and David J. Craik: Twists, Knots, and Rings in Proteins. STRUCTURAL DEFINITION OF THE CYCLOTIDE FRAMEWORK
J. Biol. Chem. 2003 278: 8606-8616. First Published on December 12, 2002; doi:10.1074/jbc.M211147200 [Abstract] [Full Text] [PDF] [Supplemental Data]

James A. Ernst and Axel T. Brunger: High Resolution Structure, Stability, and Synaptotagmin Binding of a Truncated Neuronal SNARE Complex
J. Biol. Chem. 2003 278: 8630-8636. First Published on December 20, 2002; doi:10.1074/jbc.M211889200 [Abstract] [Full Text] [PDF]

Christian Heinz, Harald Engelhardt, and Michael Niederweis: The Core of the Tetrameric Mycobacterial Porin MspA Is an Extremely Stable $beta$ -Sheet Domain
J. Biol. Chem. 2003 278: 8678-8685. First Published on December 25, 2002; doi:10.1074/jbc.M212280200 [Abstract] [Full Text] [PDF]

Wen-Ji Dong, John M. Robinson, Scott Stagg, Jun Xing, and Herbert C. Cheung: Ca²⁺-induced Conformational Transition in the Inhibitory and Regulatory Regions of Cardiac Troponin I
J. Biol. Chem. 2003 278: 8686-8692. First Published on January 2, 2003; doi:10.1074/jbc.M212886200 [Abstract] [Full Text] [PDF]

Ronald A. Li, Irene L. Ennis, Tian Xue, Hai M. Nguyen, Gordon F. Tomaselli, Alan L. Goldin, and Eduardo Marbán: Molecular Basis of Isoform-specific µ-Conotoxin Block of Cardiac, Skeletal Muscle, and Brain Na⁺ Channels
J. Biol. Chem. 2003 278: 8717-8724. First Published on December 5, 2002; doi:10.1074/jbc.M210882200 [Abstract] [Full Text] [PDF]

Atsushi Arakaki, John Webb, and Tadashi Matsunaga: A Novel Protein Tightly Bound to Bacterial Magnetic Particles in Magnetospirillum magneticum Strain AMB-1
J. Biol. Chem. 2003 278: 8745-8750. First Published on December 19, 2002; doi:10.1074/jbc.M211729200 [Abstract] [Full Text] [PDF]

Jeffrey E. Lee, Kenneth A. Cornell, Michael K. Riscoe, and P. Lynne Howell: Structure of Escherichia coli 5'-Methylthioadenosine/ S-Adenosylhomocysteine Nucleosidase Inhibitor Complexes Provide Insight into the Conformational Changes Required for Substrate Binding and Catalysis
J. Biol. Chem. 2003 278: 8761-8770. First Published on December 20, 2002; doi:10.1074/jbc.M210836200 [Abstract] [Full Text] [PDF]

Enzyme Catalysis and Regulation:

Russell Betts, Shantel Weinsheimer, Grant E. Blouse, and John Anagli: Structural Determinants of the Calpain Inhibitory Activity of Calpastatin Peptide B27-WT
J. Biol. Chem. 2003 278: 7800-7809. First Published on December 24, 2002; doi:10.1074/jbc.M208350200 [Abstract] [Full Text] [PDF]

Victor V. Zinoviev, Alexey A. Evdokimov, Ernst G. Malygin, Samuel L. Schlagman, and Stanley Hattman: Bacteriophage T4 Dam DNA-(N⁶-adenine)-methyltransferase. PROCESSIVITY AND ORIENTATION TO THE METHYLATION TARGET
J. Biol. Chem. 2003 278: 7829-7833. First Published on December 24, 2002; doi:10.1074/jbc.M210769200 [Abstract] [Full Text] [PDF]

Shivakumara Bheemanaik, Siddamadappa Chandrashekaran, Valakunja Nagaraja, and Desirazu N. Rao: Kinetic and Catalytic Properties of Dimeric KpnI DNA Methyltransferase
J. Biol. Chem. 2003 278: 7863-7874. First Published on December 28, 2002; doi:10.1074/jbc.M211458200 [Abstract] [Full Text] [PDF]

Rainer Kalscheuer and Alexander Steinbüchel: A Novel Bifunctional Wax Ester Synthase/Acyl-CoA:Diacylglycerol Acyltransferase Mediates Wax Ester and Triacylglycerol Biosynthesis in Acinetobacter calcoaceticus ADP1
J. Biol. Chem. 2003 278: 8075-8082. First Published on December 26, 2002; doi:10.1074/jbc.M210533200 [Abstract] [Full Text] [PDF]

Hua Zou, Ruomei Yang, Junshan Hao, Jean Wang, Chaohong Sun, Stephen W. Fesik, Joe C. Wu, Kevin J. Tomaselli, and Robert C. Armstrong: Regulation of the Apaf-1/Caspase-9 Apoptosome by Caspase-3 and XIAP
J. Biol. Chem. 2003 278: 8091-8098. First Published on December 27, 2002; doi:10.1074/jbc.M204783200 [Abstract] [Full Text] [PDF]

Salem Chouchane, Stefania Girotto, Sofia Kapetanaki, Johannes P. M. Schelvis, Shengwei Yu, and Richard S. Magliozzo: Analysis of Heme Structural Heterogeneity in Mycobacterium tuberculosis Catalase-Peroxidase (KatG)
J. Biol. Chem. 2003 278: 8154-8162. First Published on December 28, 2002; doi:10.1074/jbc.M208256200 [Abstract] [Full Text] [PDF]

James Flynn, Jing-Yuan Fang, Judy A. Mikovits, and Norbert O. Reich: A Potent Cell-active Allosteric Inhibitor of Murine DNA Cytosine C⁵ Methyltransferase
J. Biol. Chem. 2003 278: 8238-8243. First Published on December 10, 2002; doi:10.1074/jbc.M209839200 [Abstract] [Full Text] [PDF]

Vanessa Rioli, Fabio C. Gozzo, Andrea S. Heimann, Alessandra Linardi, José E. Krieger, Cláudio S. Shida, Paulo C. Almeida, Stephen Hyslop, Marcos N. Eberlin, and Emer S. Ferro: Novel Natural Peptide Substrates for Endopeptidase 24.15, Neurolysin, and Angiotensin-converting Enzyme
J. Biol. Chem. 2003 278: 8547-8555. First Published on December 24, 2002; doi:10.1074/jbc.M212030200 [Abstract] [Full Text] [PDF]

Jin Zhou, Huong T. Pham, and Gernot Walter: The Formation and Activity of PP2A Holoenzymes Do Not Depend on the Isoform of the Catalytic Subunit
J. Biol. Chem. 2003 278: 8617-8622. First Published on December 26, 2002; doi:10.1074/jbc.M211181200 [Abstract] [Full Text] [PDF]

Ylva Ivarsson, Aaron J. Mackey, Maryam Edalat, William R. Pearson, and Bengt Mannervik: Identification of Residues in Glutathione Transferase Capable of Driving Functional Diversification in Evolution. A NOVEL APPROACH TO PROTEIN REDESIGN
J. Biol. Chem. 2003 278: 8733-8738. First Published on December 16, 2002; doi:10.1074/jbc.M211776200 [Abstract] [Full Text] [PDF]

Metabolism and Bioenergetics:

So Young Lee, Bok Luel Lee, and Kenneth Söderhäll: Processing of an Antibacterial Peptide from Hemocyanin of the Freshwater Crayfish Pacifastacus leniusculus
J. Biol. Chem. 2003 278: 7927-7933. First Published on December 18, 2002; doi:10.1074/jbc.M209239200 [Abstract] [Full Text] [PDF]

J. Richard Dickinson, L. Eshantha J. Salgado, and Michael J. E. Hewlins: The Catabolism of Amino Acids to Long Chain and Complex Alcohols in Saccharomyces cerevisiae
J. Biol. Chem. 2003 278: 8028-8034. First Published on December 23, 2002; doi:10.1074/jbc.M211914200 [Abstract] [Full Text] [PDF]

Manuel Hervás, Eugene Myshkin, Nadejda Vintonenko, Miguel A. De la Rosa, George S. Bullerjahn, and José A. Navarro: Mutagenesis of Prochlorothrix Plastocyanin Reveals Additional Features in Photosystem I Interactions
J. Biol. Chem. 2003 278: 8179-8183. First Published on December 30, 2002; doi:10.1074/jbc.M211913200 [Abstract] [Full Text] [PDF]

Matthew Whiteman, Jia Ling Siau, and Barry Halliwell: Lack of Tyrosine Nitration by Hypochlorous Acid in the Presence of Physiological Concentrations of Nitrite. IMPLICATIONS FOR THE ROLE OF NITRYL CHLORIDE IN TYROSINE NITRATION IN VIVO
J. Biol. Chem. 2003 278: 8380-8384. First Published on December 9, 2002; doi:10.1074/jbc.M211086200 [Abstract] [Full Text] [PDF]

Glycobiology and Extracellular Matrices:

Li Shao, Daniel J. Moloney, and Robert Haltiwanger: Fringe Modifies O-Fucose on Mouse Notch1 at Epidermal Growth Factor-like Repeats within the Ligand-binding Site and the Abruptex Region
J. Biol. Chem. 2003 278: 7775-7782. First Published on December 16, 2002; doi:10.1074/jbc.M212221200 [Abstract] [Full Text] [PDF]

Honoo Satake, Helen Y. Chen, and Ajit Varki: Genes Modulated by Expression of GD3 Synthase in Chinese Hamster Ovary Cells. EVIDENCE THAT THE Tis21 GENE IS INVOLVED IN THE INDUCTION OF GD3 9-O-ACETYLATION
J. Biol. Chem. 2003 278: 7942-7948. First Published on December 18, 2002; doi:10.1074/jbc.M210565200 [Abstract] [Full Text] [PDF]

Coralee E. Tye, Kevin R. Rattray, Kevin J. Warner, Jonathan A. R. Gordon, Jaro Sodek, Graeme K. Hunter, and Harvey A. Goldberg: Delineation of the Hydroxyapatite-nucleating Domains of Bone Sialoprotein
J. Biol. Chem. 2003 278: 7949-7955. First Published on December 18, 2002; doi:10.1074/jbc.M211915200 [Abstract] [Full Text] [PDF]

Sarah J. Luchansky, Kevin J. Yarema, Saori Takahashi, and Carolyn R. Bertozzi: GlcNAc 2-Epimerase Can Serve a Catabolic Role in Sialic Acid Metabolism
J. Biol. Chem. 2003 278: 8035-8042. First Published on December 23, 2002; doi:10.1074/jbc.M212127200 [Abstract] [Full Text] [PDF]

Sadako Inoue, Geetha L. Poongodi, Nimmagadda Suresh, Harold J. Jennings, and Yasuo Inoue: Discovery of an $alpha$ 2,9-PolyNeu5Ac Glycoprotein in C-1300 Murine Neuroblastoma (Clone NB41A3)
J. Biol. Chem. 2003 278: 8541-8546. First Published on December 18, 2002; doi:10.1074/jbc.M212799200 [Abstract] [Full Text] [PDF]

Lipids and Lipoproteins:

Michael S. Glickman: The mmaA2 Gene of Mycobacterium tuberculosis Encodes the Distal Cyclopropane Synthase of the $alpha$ -Mycolic Acid
J. Biol. Chem. 2003 278: 7844-7849. First Published on December 26, 2002; doi:10.1074/jbc.M212458200 [Abstract] [Full Text] [PDF]

Pablo Mardones, Antoine Pilon, Muriel Bouly, Daniel Duran, Takako Nishimoto, Hiroyuki Arai, Karen F. Kozarsky, Marcela Altayó, Juan Francisco Miquel, Gerald Luc, Veronique Clavey, Bart Staels, and Attilio Rigotti: Fibrates Down-regulate Hepatic Scavenger Receptor Class B Type I Protein Expression in Mice
J. Biol. Chem. 2003 278: 7884-7890. First Published on January 2, 2003; doi:10.1074/jbc.M211627200 [Abstract] [Full Text] [PDF]

Xianlin Han, Hua Cheng, John D. Fryer, Anne M. Fagan, and David M. Holtzman: Novel Role for Apolipoprotein E in the Central Nervous System. MODULATION OF SULFATIDE CONTENT
J. Biol. Chem. 2003 278: 8043-8051. First Published on December 24, 2002; doi:10.1074/jbc.M212340200 [Abstract] [Full Text] [PDF]

Tina Garofalo, Roberta Misasi, Vincenzo Mattei, Anna Maria Giammarioli, Walter Malorni, Giuseppe M. Pontieri, Antonio Pavan, and Maurizio Sorice: Association of the Death-inducing Signaling Complex with Microdomains after Triggering through CD95/Fas. EVIDENCE FOR CASPASE-8-GANGLIOSIDE INTERACTION IN T CELLS
J. Biol. Chem. 2003 278: 8309-8315. First Published on December 23, 2002; doi:10.1074/jbc.M207618200 [Abstract] [Full Text] [PDF]

John T. Tansey, Anne M. Huml, Rainbow Vogt, Kathryn E. Davis, Jennifer M. Jones, Kathryn A. Fraser, Dawn L. Brasaemle, Alan R. Kimmel, and Constantine Londos: Functional Studies on Native and Mutated Forms of Perilipins. A ROLE IN PROTEIN KINASE A-MEDIATED LIPOLYSIS OF TRIACYLGLYCEROLS IN CHINESE HAMSTER OVARY CELLS
J. Biol. Chem. 2003 278: 8401-8406. First Published on December 10, 2002; doi:10.1074/jbc.M211005200 [Abstract] [Full Text] [PDF]

Maria Edman, Stefan Berg, Patrik Storm, Malin Wikström, Susanne Vikström, Anders Öhman, and Åke Wieslander: Structural Features of Glycosyltransferases Synthesizing Major Bilayer and Nonbilayer-prone Membrane Lipids in Acholeplasma laidlawii and Streptococcus pneumoniae
J. Biol. Chem. 2003 278: 8420-8428. First Published on December 2, 2002; doi:10.1074/jbc.M211492200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Kenji Asai, Tetsuya Hirabayashi, Toshiaki Houjou, Naonori Uozumi, Ryo Taguchi, and Takao Shimizu: Human Group IVC Phospholipase A₂ (cPLA₂ $gamma$ ). ROLES IN THE MEMBRANE REMODELING AND ACTIVATION INDUCED BY OXIDATIVE STRESS
J. Biol. Chem. 2003 278: 8809-8814. First Published on December 26, 2002; doi:10.1074/jbc.M212117200 [Abstract] [Full Text] [PDF]

Membrane Transport, Structure, Function, and Biogenesis:

Ulrike D. Epple, Eeva-Liisa Eskelinen, and Michael Thumm: Intravacuolar Membrane Lysis in Saccharomyces cerevisiae. DOES VACUOLAR TARGETING OF Cvt17/Aut5p AFFECT ITS FUNCTION?
J. Biol. Chem. 2003 278: 7810-7821. First Published on December 22, 2002; doi:10.1074/jbc.M209309200 [Abstract] [Full Text] [PDF]

Wen-jie Luo, Hong Wang, Hongqiao Li, Benny S. Kim, Sanjiv Shah, Hahn-Jun Lee, Gopal Thinakaran, Tae-Wan Kim, Gang Yu, and Huaxi Xu: PEN-2 and APH-1 Coordinately Regulate Proteolytic Processing of Presenilin 1
J. Biol. Chem. 2003 278: 7850-7854. First Published on January 8, 2003; doi:10.1074/jbc.C200648200 [Abstract] [Full Text] [PDF]

Elliott M. Kanner, Martin Friedlander, and Sanford M. Simon: Co-translational Targeting and Translocation of the Amino Terminus of Opsin across the Endoplasmic Membrane Requires GTP but Not ATP
J. Biol. Chem. 2003 278: 7920-7926. First Published on December 16, 2002; doi:10.1074/jbc.M207462200 [Abstract] [Full Text] [PDF]

Frits Kamp, Wen Guo, Ricardo Souto, Paul F. Pilch, Barbara E. Corkey, and James A. Hamilton: Rapid Flip-flop of Oleic Acid across the Plasma Membrane of Adipocytes
J. Biol. Chem. 2003 278: 7988-7995. First Published on December 23, 2002; doi:10.1074/jbc.M206648200 [Abstract] [Full Text] [PDF]

Traude Beilharz, Billie Egan, Pamela A. Silver, Kay Hofmann, and Trevor Lithgow: Bipartite Signals Mediate Subcellular Targeting of Tail-anchored Membrane Proteins in Saccharomyces cerevisiae
J. Biol. Chem. 2003 278: 8219-8223. First Published on January 3, 2003; doi:10.1074/jbc.M212725200 [Abstract] [Full Text] [PDF]

Philip Edward Lapinski, Gayatri Raghuraman, and Malini Raghavan: Nucleotide Interactions with Membrane-bound Transporter Associated with Antigen Processing Proteins
J. Biol. Chem. 2003 278: 8229-8237. First Published on December 25, 2002; doi:10.1074/jbc.M208930200 [Abstract] [Full Text] [PDF]

Mark F. Rosenberg, Alhaji Bukar Kamis, Richard Callaghan, Christopher F. Higgins, and Robert C. Ford: Three-dimensional Structures of the Mammalian Multidrug Resistance P-glycoprotein Demonstrate Major Conformational Changes in the Transmembrane Domains upon Nucleotide Binding
J. Biol. Chem. 2003 278: 8294-8299. First Published on December 25, 2002; doi:10.1074/jbc.M211758200 [Abstract] [Full Text] [PDF]

Colin A. Syme, Kirk L. Hamilton, Heather M. Jones, Aaron C. Gerlach, LeeAnn Giltinan, Glenn D. Papworth, Simon C. Watkins, Neil A. Bradbury, and Daniel C. Devor: Trafficking of the Ca²⁺-activated K⁺ Channel, hIK1, Is Dependent upon a C-terminal Leucine Zipper
J. Biol. Chem. 2003 278: 8476-8486. First Published on December 18, 2002; doi:10.1074/jbc.M210072200 [Abstract] [Full Text] [PDF]

Christine A. Fargeas, Mareike Florek, Wieland B. Huttner, and Denis Corbeil: Characterization of Prominin-2, a New Member of the Prominin Family of Pentaspan Membrane Glycoproteins
J. Biol. Chem. 2003 278: 8586-8596. First Published on January 3, 2003; doi:10.1074/jbc.M210640200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Annett Koch, Meinolf Thiemann, Markus Grabenbauer, Yisang Yoon, Mark A. McNiven, and Michael Schrader: Dynamin-like Protein 1 Is Involved in Peroxisomal Fission
J. Biol. Chem. 2003 278: 8597-8605. First Published on December 23, 2002; doi:10.1074/jbc.M211761200 [Abstract] [Full Text] [PDF]

Jérôme Jullien, Vincent Guili, Edmund A. Derrington, Jean-Luc Darlix, Louis F. Reichardt, and Brian B. Rudkin: Trafficking of TrkA-Green Fluorescent Protein Chimerae during Nerve Growth Factor-induced Differentiation
J. Biol. Chem. 2003 278: 8706-8716. First Published on November 15, 2002; doi:10.1074/jbc.M202401200 [Abstract] [Full Text] [PDF]

Katy Janvier, Heather Craig, Douglas Hitchin, Ricardo Madrid, Nathalie Sol-Foulon, Louis Renault, Jacqueline Cherfils, Dan Cassel, Serge Benichou, and John Guatelli: HIV-1 Nef Stabilizes the Association of Adaptor Protein Complexes with Membranes
J. Biol. Chem. 2003 278: 8725-8732. First Published on December 16, 2002; doi:10.1074/jbc.M210115200 [Abstract] [Full Text] [PDF]

Arowu R. Tanaka, Sumiko Abe-Dohmae, Tomohiro Ohnishi, Ryo Aoki, Gaku Morinaga, Kei-ichiro Okuhira, Yuika Ikeda, Fumi Kano, Michinori Matsuo, Noriyuki Kioka, Teruo Amachi, Masayuki Murata, Shinji Yokoyama, and Kazumitsu Ueda: Effects of Mutations of ABCA1 in the First Extracellular Domain on Subcellular Trafficking and ATP Binding/Hydrolysis
J. Biol. Chem. 2003 278: 8815-8819. First Published on December 31, 2002; doi:10.1074/jbc.M206885200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Yong Li, David Dinsdale, and Paul Glynn: Protein Domains, Catalytic Activity, and Subcellular Distribution of Neuropathy Target Esterase in Mammalian Cells
J. Biol. Chem. 2003 278: 8820-8825. First Published on January 3, 2003; doi:10.1074/jbc.M210743200 [Abstract] [Full Text] [PDF]

Megan L. Smart, Ben Gu, Rekha G. Panchal, James Wiley, Brett Cromer, David A. Williams, and Steven Petrou: P2X7 Receptor Cell Surface Expression and Cytolytic Pore Formation Are Regulated by a Distal C-terminal Region
J. Biol. Chem. 2003 278: 8853-8860. First Published on December 20, 2002; doi:10.1074/jbc.M211094200 [Abstract] [Full Text] [PDF]

Molecular Basis Of Cell and Developmental Biology:

Courtney C. Harper, Jeremy M. Berg, and Stephen J. Gould: PEX5 Binds the PTS1 Independently of Hsp70 and the Peroxin PEX12
J. Biol. Chem. 2003 278: 7897-7901. First Published on November 26, 2002; doi:10.1074/jbc.M206651200 [Abstract] [Full Text] [PDF]

Yu-Ying He, Jian-Li Huang, Dario C. Ramirez, and Colin F. Chignell: Role of Reduced Glutathione Efflux in Apoptosis of Immortalized Human Keratinocytes Induced by UVA
J. Biol. Chem. 2003 278: 8058-8064. First Published on December 26, 2002; doi:10.1074/jbc.M207781200 [Abstract] [Full Text] [PDF]

Nataliya Rozenvayn and Robert Flaumenhaft: Protein kinase C Mediates Translocation of Type II Phosphatidylinositol 5-Phosphate 4-Kinase Required for Platelet $alpha$ -Granule Secretion
J. Biol. Chem. 2003 278: 8126-8134. First Published on December 30, 2002; doi:10.1074/jbc.M206493200 [Abstract] [Full Text] [PDF]

Shigeru Kanda, Yasushi Mochizuki, Takashi Suematsu, Yasuyoshi Miyata, Koichiro Nomata, and Hiroshi Kanetake: Sonic Hedgehog Induces Capillary Morphogenesis by Endothelial Cells through Phosphoinositide 3-Kinase
J. Biol. Chem. 2003 278: 8244-8249. First Published on January 3, 2003; doi:10.1074/jbc.M210635200 [Abstract] [Full Text] [PDF]

Robyn Meech, Helen Makarenkova, David B. Edelman, and Frederick S. Jones: The Homeodomain Protein Barx2 Promotes Myogenic Differentiation and Is Regulated by Myogenic Regulatory Factors
J. Biol. Chem. 2003 278: 8269-8278. First Published on December 16, 2002; doi:10.1074/jbc.M207617200 [Abstract] [Full Text] [PDF]

Niels A. Jensen, Karen M. Pedersen, Frederikke Lihme, Lene Rask, Jakob V. Nielsen, Thomas E. Rasmussen, and Cathy Mitchelmore: Astroglial c-Myc Overexpression Predisposes Mice to Primary Malignant Gliomas
J. Biol. Chem. 2003 278: 8300-8308. First Published on December 24, 2002; doi:10.1074/jbc.M211195200 [Abstract] [Full Text] [PDF]

Detlef Vullhorst and Andres Buonanno: Characterization of General Transcription Factor 3, a Transcription Factor Involved in Slow Muscle-specific Gene Expression
J. Biol. Chem. 2003 278: 8370-8379. First Published on December 9, 2002; doi:10.1074/jbc.M209361200 [Abstract] [Full Text] [PDF]

Noriyuki Asaba, Toshihiko Hanada, Atsuko Takeuchi, and Athar H. Chishti: Direct Interaction with a Kinesin-related Motor Mediates Transport of Mammalian Discs Large Tumor Suppressor Homologue in Epithelial Cells
J. Biol. Chem. 2003 278: 8395-8400. First Published on December 21, 2002; doi:10.1074/jbc.M210362200 [Abstract] [Full Text] [PDF]

Pieta K. Mattila, Marjo Salminen, Takashi Yamashiro, and Pekka Lappalainen: Mouse MIM, a Tissue-specific Regulator of Cytoskeletal Dynamics, Interacts with ATP-Actin Monomers through Its C-terminal WH2 Domain
J. Biol. Chem. 2003 278: 8452-8459. First Published on December 13, 2002; doi:10.1074/jbc.M212113200 [Abstract] [Full Text] [PDF]

Dean S. Rosenthal, Alfredo Velena, Feng-Pai Chou, Richard Schlegel, Radharaman Ray, Betty Benton, Dana Anderson, William J. Smith, and Cynthia M. Simbulan-Rosenthal: Expression of Dominant-negative Fas-associated Death Domain Blocks Human Keratinocyte Apoptosis and Vesication Induced by Sulfur Mustard
J. Biol. Chem. 2003 278: 8531-8540. First Published on December 12, 2002; doi:10.1074/jbc.M209549200 [Abstract] [Full Text] [PDF]

Myungjo You, Xuenan Xuan, Naotoshi Tsuji, Tsugihiko Kamio, DeMar Taylor, Naoyoshi Suzuki, and Kozo Fujisaki: Identification and Molecular Characterization of a Chitinase from the Hard Tick Haemaphysalis longicornis
J. Biol. Chem. 2003 278: 8556-8563. First Published on December 26, 2002; doi:10.1074/jbc.M206831200 [Abstract] [Full Text] [PDF]

Yin Xu and Qin Yu: E-cadherin Negatively Regulates CD44-Hyaluronan Interaction and CD44-mediated Tumor Invasion and Branching Morphogenesis
J. Biol. Chem. 2003 278: 8661-8668. First Published on January 2, 2003; doi:10.1074/jbc.M208181200 [Abstract] [Full Text] [PDF]

Janice M. Ascano, Levi J. Beverly, and Anthony J. Capobianco: The C-terminal PDZ-Ligand of JAGGED1 Is Essential for Cellular Transformation
J. Biol. Chem. 2003 278: 8771-8779. First Published on December 20, 2002; doi:10.1074/jbc.M211427200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Oleg M. Alekseev, David C. Bencic, Richard T. Richardson, Esther E. Widgren, and Michael G. O'Rand: Overexpression of the Linker Histone-binding Protein tNASP Affects Progression through the Cell Cycle
J. Biol. Chem. 2003 278: 8846-8852. First Published on December 30, 2002; doi:10.1074/jbc.M210352200 [Abstract] [Full Text] [PDF]

Mechanisms Of Signal Transduction:

Jeremy Copp, Michael Marino, Manidipa Banerjee, Partho Ghosh, and Peter van der Geer: Multiple Regions of Internalin B Contribute to Its Ability to Turn on the Ras-Mitogen-activated Protein Kinase Pathway
J. Biol. Chem. 2003 278: 7783-7789. First Published on December 17, 2002; doi:10.1074/jbc.M211666200 [Abstract] [Full Text] [PDF]

Hiroshi Kobayashi, Mika Suzuki, Yoshiko Tanaka, Naohiro Kanayama, and Toshihiko Terao: A Kunitz-type Protease Inhibitor, Bikunin, Inhibits Ovarian Cancer Cell Invasion by Blocking the Calcium-dependent Transforming Growth Factor- $beta$ 1 Signaling Cascade
J. Biol. Chem. 2003 278: 7790-7799. First Published on December 20, 2002; doi:10.1074/jbc.M210407200 [Abstract] [Full Text] [PDF]

Andreas Gille, Katharina Wenzel-Seifert, Michael B. Doughty, and Roland Seifert: GDP Affinity and Order State of the Catalytic Site Are Critical for Function of Xanthine Nucleotide-selective G $alpha$ _s Proteins
J. Biol. Chem. 2003 278: 7822-7828. First Published on December 23, 2002; doi:10.1074/jbc.M210162200 [Abstract] [Full Text] [PDF]

Satoko Sudo, Jin Kumagai, Shinya Nishi, Sharon Layfield, Tania Ferraro, Ross A. D. Bathgate, and Aaron J. W. Hsueh: H3 Relaxin Is a Specific Ligand for LGR7 and Activates the Receptor by Interacting with Both the Ectodomain and the Exoloop 2
J. Biol. Chem. 2003 278: 7855-7862. First Published on December 27, 2002; doi:10.1074/jbc.M212457200 [Abstract] [Full Text] [PDF]

Ezra Wiater and Wylie Vale: Inhibin Is an Antagonist of Bone Morphogenetic Protein Signaling
J. Biol. Chem. 2003 278: 7934-7941. First Published on December 18, 2002; doi:10.1074/jbc.M209710200 [Abstract] [Full Text] [PDF]

Esteban Chaves-Olarte, Enrique Freer, Andrea Parra, Caterina Guzmán-Verri, Edgardo Moreno, and Monica Thelestam: R-Ras Glucosylation and Transient RhoA Activation Determine the Cytopathic Effect Produced by Toxin B Variants from Toxin A-negative Strains of Clostridium difficile
J. Biol. Chem. 2003 278: 7956-7963. First Published on December 19, 2002; doi:10.1074/jbc.M209244200 [Abstract] [Full Text] [PDF]

Aaron T. Jacobs and Louis J. Ignarro: Nuclear Factor- $kappa$ B and Mitogen-activated Protein Kinases Mediate Nitric Oxide-enhanced Transcriptional Expression of Interferon- $beta$
J. Biol. Chem. 2003 278: 8018-8027. First Published on December 23, 2002; doi:10.1074/jbc.M211642200 [Abstract] [Full Text] [PDF]

Tanja Eichmann, Kristina Lorenz, Michaela Hoffmann, Jörg Brockmann, Cornelius Krasel, Martin J. Lohse, and Ursula Quitterer: The Amino-terminal Domain of G-protein-coupled Receptor Kinase 2 Is a Regulatory G $beta$ $gamma$ Binding Site
J. Biol. Chem. 2003 278: 8052-8057. First Published on December 16, 2002; doi:10.1074/jbc.M204795200 [Abstract] [Full Text] [PDF]

Shimon Reif, Alon Lang, Jeffery N. Lindquist, Yutaka Yata, Erwin Gäbele, Andrew Scanga, David A. Brenner, and Richard A. Rippe: The Role of Focal Adhesion Kinase-Phosphatidylinositol 3-Kinase-Akt Signaling in Hepatic Stellate Cell Proliferation and Type I Collagen Expression
J. Biol. Chem. 2003 278: 8083-8090. First Published on December 26, 2002; doi:10.1074/jbc.M212927200 [Abstract] [Full Text] [PDF]

Tianqing Peng, Xiangru Lu, Ming Lei, and Qingping Feng: Endothelial Nitric-oxide Synthase Enhances Lipopolysaccharide-stimulated Tumor Necrosis Factor- $alpha$ Expression via cAMP-mediated p38 MAPK Pathway in Cardiomyocytes
J. Biol. Chem. 2003 278: 8099-8105. First Published on December 27, 2002; doi:10.1074/jbc.M207288200 [Abstract] [Full Text] [PDF]

Marion B. Sewer and Michael R. Waterman: cAMP-dependent Protein Kinase Enhances CYP17 Transcription via MKP-1 Activation in H295R Human Adrenocortical Cells
J. Biol. Chem. 2003 278: 8106-8111. First Published on December 27, 2002; doi:10.1074/jbc.M210264200 [Abstract] [Full Text] [PDF]

Kailesh Gopalbhai, Gregor Jansen, Geneviève Beauregard, Malcolm Whiteway, France Dumas, Cunle Wu, and Sylvain Meloche: Negative Regulation of MAPKK by Phosphorylation of a Conserved Serine Residue Equivalent to Ser²¹² of MEK1
J. Biol. Chem. 2003 278: 8118-8125. First Published on December 27, 2002; doi:10.1074/jbc.M211870200 [Abstract] [Full Text] [PDF]

Katerina Tumova, Rafal M. Iwasiow, and Mario Tiberi: Insight into the Mechanism of Dopamine D1-like Receptor Activation. EVIDENCE FOR A MOLECULAR INTERPLAY BETWEEN THE THIRD EXTRACELLULAR LOOP AND THE CYTOPLASMIC TAIL
J. Biol. Chem. 2003 278: 8146-8153. First Published on December 30, 2002; doi:10.1074/jbc.M208059200 [Abstract] [Full Text] [PDF]

Sabina Visconti, Lorenzo Camoni, Maria Rosaria Fullone, Marco Lalle, Mauro Marra, and Patrizia Aducci: Mutational Analysis of the Interaction between 14-3-3 Proteins and Plant Plasma Membrane H⁺-ATPase
J. Biol. Chem. 2003 278: 8172-8178. First Published on December 30, 2002; doi:10.1074/jbc.M211039200 [Abstract] [Full Text] [PDF]

Junhui Sun, Le Xu, Jerry P. Eu, Jonathan S. Stamler, and Gerhard Meissner: Nitric Oxide, NOC-12, and S-Nitrosoglutathione Modulate the Skeletal Muscle Calcium Release Channel/Ryanodine Receptor by Different Mechanisms. AN ALLOSTERIC FUNCTION FOR O₂ IN S-NITROSYLATION OF THE CHANNEL
J. Biol. Chem. 2003 278: 8184-8189. First Published on December 30, 2002; doi:10.1074/jbc.M211940200 [Abstract] [Full Text] [PDF]

Michael W. Greene, Hiroshi Sakaue, Lihong Wang, Dario R. Alessi, and Richard A. Roth: Modulation of Insulin-stimulated Degradation of Human Insulin Receptor Substrate-1 by Serine 312 Phosphorylation
J. Biol. Chem. 2003 278: 8199-8211. First Published on January 1, 2003; doi:10.1074/jbc.M209153200 [Abstract] [Full Text] [PDF]

Guoxin Kang, Jamie W. Joseph, Oleg G. Chepurny, Marie Monaco, Michael B. Wheeler, Johannes L. Bos, Frank Schwede, Hans-G. Genieser, and George G. Holz: Epac-selective cAMP Analog 8-pCPT-2'-O-Me-cAMP as a Stimulus for Ca²⁺-induced Ca²⁺ Release and Exocytosis in Pancreatic $beta$ -Cells
J. Biol. Chem. 2003 278: 8279-8285. First Published on December 20, 2002; doi:10.1074/jbc.M211682200 [Abstract] [Full Text] [PDF]

Svetlana V. Komarova, Mary F. Pilkington, A. Frederik Weidema, S. Jeffrey Dixon, and Stephen M. Sims: RANK Ligand-induced Elevation of Cytosolic Ca²⁺ Accelerates Nuclear Translocation of Nuclear Factor $kappa$ B in Osteoclasts
J. Biol. Chem. 2003 278: 8286-8293. First Published on December 20, 2002; doi:10.1074/jbc.M206421200 [Abstract] [Full Text] [PDF]

Izabela Sokal, Guang Hu, Yan Liang, Muling Mao, Theodore G. Wensel, and Krzysztof Palczewski: Identification of Protein Kinase C Isozymes Responsible for the Phosphorylation of Photoreceptor-specific RGS9-1 at Ser⁴⁷⁵
J. Biol. Chem. 2003 278: 8316-8325. First Published on December 23, 2002; doi:10.1074/jbc.M211782200 [Abstract] [Full Text] [PDF]

Song Huang, Tecla Dudez, Isabelle Scerri, Marc A. Thomas, Ben N. G. Giepmans, Susanne Suter, and Marc Chanson: Defective Activation of c-Src in Cystic Fibrosis Airway Epithelial Cells Results in Loss of Tumor Necrosis Factor- $alpha$ -induced Gap Junction Regulation
J. Biol. Chem. 2003 278: 8326-8332. First Published on December 27, 2002; doi:10.1074/jbc.M208264200 [Abstract] [Full Text] [PDF]

Hongwei Zhang, Jia-Zheng Zhang, Cristina I. Danila, and Susan L. Hamilton: A Noncontiguous, Intersubunit Binding Site for Calmodulin on the Skeletal Muscle Ca²⁺ Release Channel
J. Biol. Chem. 2003 278: 8348-8355. First Published on December 31, 2002; doi:10.1074/jbc.M209565200 [Abstract] [Full Text] [PDF]

Gregory G. Tall, Andrejs M. Krumins, and Alfred G. Gilman: Mammalian Ric-8A (Synembryn) Is a Heterotrimeric G $alpha$ Protein Guanine Nucleotide Exchange Factor
J. Biol. Chem. 2003 278: 8356-8362. First Published on December 30, 2002; doi:10.1074/jbc.M211862200 [Abstract] [Full Text] [PDF]

KeriLyn R. Wick, Eric D. Werner, Paul Langlais, Fresnida J. Ramos, Lily Q. Dong, Steven E. Shoelson, and Feng Liu: Grb10 Inhibits Insulin-stimulated Insulin Receptor Substrate (IRS)-Phosphatidylinositol 3-Kinase/Akt Signaling Pathway by Disrupting the Association of IRS-1/IRS-2 with the Insulin Receptor
J. Biol. Chem. 2003 278: 8460-8467. First Published on December 18, 2002; doi:10.1074/jbc.M208518200 [Abstract] [Full Text] [PDF]

Jan Heidemann, Hitoshi Ogawa, Michael B. Dwinell, Parvaneh Rafiee, Christian Maaser, Henning R. Gockel, Mary F. Otterson, David M. Ota, Norbert Lügering, Wolfram Domschke, and David G. Binion: Angiogenic Effects of Interleukin 8 (CXCL8) in Human Intestinal Microvascular Endothelial Cells Are Mediated by CXCR2
J. Biol. Chem. 2003 278: 8508-8515. First Published on December 20, 2002; doi:10.1074/jbc.M208231200 [Abstract] [Full Text] [PDF]

Nianyu Li, Kathy Ragheb, Gretchen Lawler, Jennie Sturgis, Bartek Rajwa, J. Andres Melendez, and J. Paul Robinson: Mitochondrial Complex I Inhibitor Rotenone Induces Apoptosis through Enhancing Mitochondrial Reactive Oxygen Species Production
J. Biol. Chem. 2003 278: 8516-8525. First Published on December 20, 2002; doi:10.1074/jbc.M210432200 [Abstract] [Full Text] [PDF]

Hidemasa Goto, Yoshihiro Yasui, Aie Kawajiri, Erich A. Nigg, Yasuhiko Terada, Masaaki Tatsuka, Koh-ichi Nagata, and Masaki Inagaki: Aurora-B Regulates the Cleavage Furrow-specific Vimentin Phosphorylation in the Cytokinetic Process
J. Biol. Chem. 2003 278: 8526-8530. First Published on November 27, 2002; doi:10.1074/jbc.M210892200 [Abstract] [Full Text] [PDF]

Idoia Gimferrer, Montse Farnós, Maria Calvo, María Mittelbrunn, Carlos Enrich, Francisco Sánchez-Madrid, Jordi Vives, and Francisco Lozano: The Accessory Molecules CD5 and CD6 Associate on the Membrane of Lymphoid T Cells
J. Biol. Chem. 2003 278: 8564-8571. First Published on December 8, 2002; doi:10.1074/jbc.M209591200 [Abstract] [Full Text] [PDF]

Yingchang Mi, Shelia D. Thomas, Xiaohua Xu, Lavona K. Casson, Donald M. Miller, and Paula J. Bates: Apoptosis in Leukemia Cells Is Accompanied by Alterations in the Levels and Localization of Nucleolin
J. Biol. Chem. 2003 278: 8572-8579. First Published on December 27, 2002; doi:10.1074/jbc.M207637200 [Abstract] [Full Text] [PDF]

Dongli Hu, Akila Mayeda, Janeen H. Trembley, Jill M. Lahti, and Vincent J. Kidd: CDK11 Complexes Promote Pre-mRNA Splicing
J. Biol. Chem. 2003 278: 8623-8629. First Published on December 24, 2002; doi:10.1074/jbc.M210057200 [Abstract] [Full Text] [PDF]

Daria Illenberger, Claudia Walliser, Joachim Strobel, Orit Gutman, Hagit Niv, Verena Gaidzik, Yoel Kloog, Peter Gierschik, and Yoav I. Henis: Rac2 Regulation of Phospholipase C- $beta$ ₂ Activity and Mode of Membrane Interactions in Intact Cells
J. Biol. Chem. 2003 278: 8645-8652. First Published on December 30, 2002; doi:10.1074/jbc.M211971200 [Abstract] [Full Text] [PDF]

Lijun Tian, Lorraine S. Coghill, Stephen H.-F. MacDonald, David L. Armstrong, and Michael J. Shipston: Leucine Zipper Domain Targets cAMP-dependent Protein Kinase to Mammalian BK Channels
J. Biol. Chem. 2003 278: 8669-8677. First Published on December 30, 2002; doi:10.1074/jbc.M211661200 [Abstract] [Full Text] [PDF]

Antonio Facchiano, Katia Russo, Angelo M. Facchiano, Francesco De Marchis, Francesco Facchiano, Domenico Ribatti, Maria S. Aguzzi, and Maurizio C. Capogrossi: Identification of a Novel Domain of Fibroblast Growth Factor 2 Controlling Its Angiogenic Properties
J. Biol. Chem. 2003 278: 8751-8760. First Published on December 20, 2002; doi:10.1074/jbc.M209936200 [Abstract] [Full Text] [PDF]

Markus Kuhlmann, Katja Horvay, Anne Strathmann, Thorsten Heinekamp, Ute Fischer, Stefan Böttner, and Wolfgang Dröge-Laser: The $alpha$ -Helical D1 Domain of the Tobacco bZIP Transcription Factor BZI-1 Interacts with the Ankyrin-repeat Protein ANK1 and Is Important for BZI-1 Function, Both in Auxin Signaling and Pathogen Response
J. Biol. Chem. 2003 278: 8786-8794. First Published on December 23, 2002; doi:10.1074/jbc.M210292200 [Abstract] [Full Text] [PDF]

Osman Cen, Magdalena M. Gorska, Susan J. Stafford, Sanjiv Sur, and Rafeul Alam: Identification of UNC119 as a Novel Activator of SRC-type Tyrosine Kinases
J. Biol. Chem. 2003 278: 8837-8845. First Published on December 19, 2002; doi:10.1074/jbc.M208261200 [Abstract] [Full Text] [PDF]

Accelerated Publications:

DNA: Replication, Repair, and Recombination:

Genes: Structure and Regulation:

Protein Synthesis, Post-Translation Modification, and Degradation:

Genomics, Proteomics, and Bioinformatics:

Protein Structure and Folding:

Enzyme Catalysis and Regulation:

Metabolism and Bioenergetics:

Glycobiology and Extracellular Matrices:

Lipids and Lipoproteins:

Membrane Transport, Structure, Function, and Biogenesis:

Molecular Basis Of Cell and Developmental Biology:

Mechanisms Of Signal Transduction: