Reflections:

Robert L. Baldwin

In Search of the Energetic Role of Peptide Hydrogen Bonds
J. Biol. Chem. 2003 278: 17581-17588. First Published on February 11, 2003; doi:10.1074/jbc.X200009200 [Full Text] [PDF]  

Accelerated Publications:

Dustin Deming, Qing Cheng, and Vasanthi Jayaraman

Is the Isolated Ligand Binding Domain a Good Model of the Domain in the Native Receptor?
J. Biol. Chem. 2003 278: 17589-17592. First Published on March 25, 2003; doi:10.1074/jbc.C300105200 [Abstract] [Full Text] [PDF]  

Dharminder Chauhan, Guilan Li, Teru Hideshima, Klaus Podar, Constantine Mitsiades, Nicholas Mitsiades, Nikhil Munshi, Surender Kharbanda, and Kenneth C. Anderson

JNK-dependent Release of Mitochondrial Protein, Smac, during Apoptosis in Multiple Myeloma (MM) Cells
J. Biol. Chem. 2003 278: 17593-17596. First Published on March 28, 2003; doi:10.1074/jbc.C300076200 [Abstract] [Full Text] [PDF]  

Torkel Vang, Hilde Abrahamsen, Sondre Myklebust, Václav Horejsí, and Kjetil Taskén

Combined Spatial and Enzymatic Regulation of Csk by cAMP and Protein Kinase A Inhibits T Cell Receptor Signaling
J. Biol. Chem. 2003 278: 17597-17600. First Published on March 28, 2003; doi:10.1074/jbc.C300077200 [Abstract] [Full Text] [PDF]  

DNA: Replication Repair and Recombination:

Hélène Gaillard, Daniel J. Fitzgerald, Corey L. Smith, Craig L. Peterson, Timothy J. Richmond, and Fritz Thoma

Chromatin Remodeling Activities Act on UV-damaged Nucleosomes and Modulate DNA Damage Accessibility to Photolyase
J. Biol. Chem. 2003 278: 17655-17663. First Published on March 11, 2003; doi:10.1074/jbc.M300770200 [Abstract] [Full Text] [PDF]  

Noëlle Mathieu, Salvatore Spicuglia, Sophie Gorbatch, Olivier Cabaud, Corinne Fernex, Christophe Verthuy, William M. Hempel, Anne-Odile Hueber, and Pierre Ferrier

Assessing the Role of the T Cell Receptor Gene Enhancer in Regulating Coding Joint Formation during V(D)J Recombination
J. Biol. Chem. 2003 278: 18101-18109. First Published on March 14, 2003; doi:10.1074/jbc.M212647200 [Abstract] [Full Text] [PDF]  

Mandy M. Peak, Janeen L. Arbuckle, and Karla K. Rodgers

The Central Domain of Core RAG1 Preferentially Recognizes Single-stranded Recombination Signal Sequence Heptamer
J. Biol. Chem. 2003 278: 18235-18240. First Published on March 18, 2003; doi:10.1074/jbc.M302041200 [Abstract] [Full Text] [PDF]  

Kai-ming Chou and Yung-chi Cheng

The Exonuclease Activity of Human Apurinic/Apyrimidinic Endonuclease (APE1). BIOCHEMICAL PROPERTIES AND INHIBITION BY THE NATURAL DINUCLEOTIDE Gp₄G
J. Biol. Chem. 2003 278: 18289-18296. First Published on March 6, 2003; doi:10.1074/jbc.M212143200 [Abstract] [Full Text] [PDF]  

Florence Le Page, Valérie Schreiber, Claudine Dhérin, Gilbert de Murcia, and Serge Boiteux

Poly(ADP-ribose) Polymerase-1 (PARP-1) Is Required in Murine Cell Lines for Base Excision Repair of Oxidative DNA Damage in the Absence of DNA Polymerase
J. Biol. Chem. 2003 278: 18471-18477. First Published on March 7, 2003; doi:10.1074/jbc.M212905200 [Abstract] [Full Text] [PDF]  

Keith P. Bjornson and Paul Modrich

Differential and Simultaneous Adenosine Di- and Triphosphate Binding by MutS
J. Biol. Chem. 2003 278: 18557-18562. First Published on March 6, 2003; doi:10.1074/jbc.M301101200 [Abstract] [Full Text] [PDF]  

Teresa Díaz-López, Marta Lages-Gonzalo, Ana Serrano-López, Carlos Alfonso, Germán Rivas, Ramón Díaz-Orejas, and Rafael Giraldo

Structural Changes in RepA, a Plasmid Replication Initiator, upon Binding to Origin DNA
J. Biol. Chem. 2003 278: 18606-18616. First Published on March 7, 2003; doi:10.1074/jbc.M212024200 [Abstract] [Full Text] [PDF]  

Genes: Structure and Regulation:

Imre Berger, Christoph Bieniossek, Christiane Schaffitzel, Markus Hassler, Eugenio Santelli, and Timothy J. Richmond

Direct Interaction of Ca²⁺/Calmodulin Inhibits Histone Deacetylase 5 Repressor Core Binding to Myocyte Enhancer Factor 2
J. Biol. Chem. 2003 278: 17625-17635. First Published on March 6, 2003; doi:10.1074/jbc.M301646200 [Abstract] [Full Text] [PDF]  

Lujian Tan, Haibing Peng, Makoto Osaki, Bob K. Choy, Philip E. Auron, Linda J. Sandell, and Mary B. Goldring

Egr-1 Mediates Transcriptional Repression of COL2A1 Promoter Activity by Interleukin-1
J. Biol. Chem. 2003 278: 17688-17700. First Published on March 11, 2003; doi:10.1074/jbc.M301676200 [Abstract] [Full Text] [PDF]  

James R. Mead, Timothy R. Hughes, Scott A. Irvine, Nishi N. Singh, and Dipak P. Ramji

Interferon- Stimulates the Expression of the Inducible cAMP Early Repressor in Macrophages through the Activation of Casein Kinase 2. A POTENTIALLY NOVEL PATHWAY FOR INTERFERON--MEDIATED INHIBITION OF GENE TRANSCRIPTION
J. Biol. Chem. 2003 278: 17741-17751. First Published on February 27, 2003; doi:10.1074/jbc.M301602200 [Abstract] [Full Text] [PDF]  

Ifeanyi J. Arinze and Yumiko Kawai

Sp Family of Transcription Factors Is Involved in Valproic Acid-induced Expression of G_i2
J. Biol. Chem. 2003 278: 17785-17791. First Published on March 6, 2003; doi:10.1074/jbc.M209430200 [Abstract] [Full Text] [PDF]  

Adriana Cabral, David F. Fischer, Wilbert P. Vermeij, and Claude Backendorf

Distinct Functional Interactions of Human Skn-1 Isoforms with Ese-1 during Keratinocyte Terminal Differentiation
J. Biol. Chem. 2003 278: 17792-17799. First Published on March 6, 2003; doi:10.1074/jbc.M300508200 [Abstract] [Full Text] [PDF]  

Matthew S. Wiebe, Tamara K. Nowling, and Angie Rizzino

Identification of Novel Domains within Sox-2 and Sox-11 Involved in Autoinhibition of DNA Binding and Partnership Specificity
J. Biol. Chem. 2003 278: 17901-17911. First Published on March 10, 2003; doi:10.1074/jbc.M212211200 [Abstract] [Full Text] [PDF]  

George A. Kassavetis, Shulin Han, Souad Naji, and E. Peter Geiduschek

The Role of Transcription Initiation Factor IIIB Subunits in Promoter Opening Probed by Photochemical Cross-linking
J. Biol. Chem. 2003 278: 17912-17917. First Published on March 10, 2003; doi:10.1074/jbc.M300743200 [Abstract] [Full Text] [PDF]  

Michaela Angermayr, Ulrich Oechsner, and Wolfhard Bandlow

Reb1p-dependent DNA Bending Effects Nucleosome Positioning and Constitutive Transcription at the Yeast Profilin Promoter
J. Biol. Chem. 2003 278: 17918-17926. First Published on March 10, 2003; doi:10.1074/jbc.M301806200 [Abstract] [Full Text] [PDF]  

Thomas Kietzmann, Anatoly Samoylenko, and Stephan Immenschuh

Transcriptional Regulation of Heme Oxygenase-1 Gene Expression by MAP Kinases of the JNK and p38 Pathways in Primary Cultures of Rat Hepatocytes
J. Biol. Chem. 2003 278: 17927-17936. First Published on March 11, 2003; doi:10.1074/jbc.M203929200 [Abstract] [Full Text] [PDF]  

Ngoc Vu-Dac, Philippe Gervois, Heidi Jakel, Maxime Nowak, Eric Baugé, Hélène Dehondt, Bart Staels, Len A. Pennacchio, Edward M. Rubin, Jamila Fruchart-Najib, and Jean-Charles Fruchart

Apolipoprotein A5, a Crucial Determinant of Plasma Triglyceride Levels, Is Highly Responsive to Peroxisome Proliferator-activated Receptor Activators
J. Biol. Chem. 2003 278: 17982-17985. First Published on March 12, 2003; doi:10.1074/jbc.M212191200 [Abstract] [Full Text] [PDF]  

Duncan M. Gascoyne, Robert M. Kypta, and Maria d. M. Vivanco

Glucocorticoids Inhibit Apoptosis during Fibrosarcoma Development by Transcriptionally Activating Bcl-x_L
J. Biol. Chem. 2003 278: 18022-18029. First Published on March 12, 2003; doi:10.1074/jbc.M301812200 [Abstract] [Full Text] [PDF]  

Gi Hoon Son, Hosung Jung, Jae Young Seong, Youngshik Choe, Dongho Geum, and Kyungjin Kim

Excision of the First Intron from the Gonadotropin-releasing Hormone (GnRH) Transcript Serves as a Key Regulatory Step for GnRH Biosynthesis
J. Biol. Chem. 2003 278: 18037-18044. First Published on March 13, 2003; doi:10.1074/jbc.M209850200 [Abstract] [Full Text] [PDF]  

Chi Y. Yun, Adolfo L. Velazquez-Dones, Susan K. Lyman, and Xiang-Dong Fu

Phosphorylation-dependent and -independent Nuclear Import of RS Domain-containing Splicing Factors and Regulators
J. Biol. Chem. 2003 278: 18050-18055. First Published on March 13, 2003; doi:10.1074/jbc.M211714200 [Abstract] [Full Text] [PDF]  

Sreerama Shetty, Khalil Bdeir, Douglas B. Cines, and Steven Idell

Induction of Plasminogen Activator Inhibitor-1 by Urokinase in Lung Epithelial Cells
J. Biol. Chem. 2003 278: 18124-18131. First Published on March 17, 2003; doi:10.1074/jbc.M207445200 [Abstract] [Full Text] [PDF]  

Ute Raffetseder, Björn Frye, Thomas Rauen, Karsten Jürchott, Hans-Dieter Royer, Petra Lynen Jansen, and Peter R. Mertens

Splicing Factor SRp30c Interaction with Y-box Protein-1 Confers Nuclear YB-1 Shuttling and Alternative Splice Site Selection
J. Biol. Chem. 2003 278: 18241-18248. First Published on February 25, 2003; doi:10.1074/jbc.M212518200 [Abstract] [Full Text] [PDF]  

Yuri A. Nedialkov, Xue Q. Gong, Stacy L. Hovde, Yuki Yamaguchi, Hiroshi Handa, James H. Geiger, Honggao Yan, and Zachary F. Burton

NTP-driven Translocation by Human RNA Polymerase II
J. Biol. Chem. 2003 278: 18303-18312. First Published on March 13, 2003; doi:10.1074/jbc.M301103200 [Abstract] [Full Text] [PDF]  

Sanjeev Das, Wafik S. El-Deiry, and Kumaravel Somasundaram

Regulation of the p53 Homolog p73 by Adenoviral Oncogene E1A
J. Biol. Chem. 2003 278: 18313-18320. First Published on March 13, 2003; doi:10.1074/jbc.M211704200 [Abstract] [Full Text] [PDF]  

Hogune Im, Changwon Park, Qin Feng, Kirby D. Johnson, Carol M. Kiekhaefer, Kyunghee Choi, Yi Zhang, and Emery H. Bresnick

Dynamic Regulation of Histone H3 Methylated at Lysine 79 within a Tissue-specific Chromatin Domain
J. Biol. Chem. 2003 278: 18346-18352. First Published on February 25, 2003; doi:10.1074/jbc.M300890200 [Abstract] [Full Text] [PDF]  

Sylvain Lesné, Fabian Docagne, Cecília Gabriel, Géraldine Liot, Debomoy K. Lahiri, Luc Buée, Laurent Plawinski, André Delacourte, Eric T. MacKenzie, Alain Buisson, and Denis Vivien

Transforming Growth Factor-1 Potentiates Amyloid- Generation in Astrocytes and in Transgenic Mice
J. Biol. Chem. 2003 278: 18408-18418. First Published on March 7, 2003; doi:10.1074/jbc.M300819200 [Abstract] [Full Text] [PDF]  

Ju-Sim Kim, Sa-Ouk Kang, and Jeong K. Lee

The Protein Complex Composed of Nickel-binding SrnQ and DNA Binding Motif-bearing SrnR of Streptomyces griseus Represses sodF Transcription in the Presence of Nickel
J. Biol. Chem. 2003 278: 18455-18463. First Published on March 17, 2003; doi:10.1074/jbc.M211740200 [Abstract] [Full Text] [PDF]  

Craig S. Hinkley, Heather A. Hirsch, Liping Gu, Brandon LaMere, and R. William Henry

The Small Nuclear RNA-activating Protein 190 Myb DNA Binding Domain Stimulates TATA Box-binding Protein-TATA Box Recognition
J. Biol. Chem. 2003 278: 18649-18657. First Published on March 5, 2003; doi:10.1074/jbc.M204247200 [Abstract] [Full Text] [PDF]  

Jung-Min Park, Takekazu Kunieda, and Takeo Kubo

The Activity of Mblk-1, a Mushroom Body-selective Transcription Factor from the Honeybee, Is Modulated by the Ras/MAPK Pathway
J. Biol. Chem. 2003 278: 18689-18694. First Published on March 12, 2003; doi:10.1074/jbc.M300486200 [Abstract] [Full Text] [PDF]  

RNA: Structure Metabolism and Catalysis:

Li Liu, Herzel Ben-Shlomo, Yu-xin Xu, Michael Zeev Stern, Igor Goncharov, Yafei Zhang, and Shulamit Michaeli

The Trypanosomatid Signal Recognition Particle Consists of Two RNA Molecules, a 7SL RNA Homologue and a Novel tRNA-like Molecule
J. Biol. Chem. 2003 278: 18271-18280. First Published on February 26, 2003; doi:10.1074/jbc.M209215200 [Abstract] [Full Text] [PDF]  

Protein Synthesis Post-Translation Modification and Degradation:

Grant P. Otto, Mary Y. Wu, Nevzat Kazgan, O. Roger Anderson, and Richard H. Kessin

Macroautophagy Is Required for Multicellular Development of the Social Amoeba Dictyostelium discoideum
J. Biol. Chem. 2003 278: 17636-17645. First Published on March 7, 2003; doi:10.1074/jbc.M212467200 [Abstract] [Full Text] [PDF]  

Alexei Stortchevoi, Umesh Varshney, and Uttam L. RajBhandary

Common Location of Determinants in Initiator Transfer RNAs for Initiator-Elongator Discrimination in Bacteria and in Eukaryotes
J. Biol. Chem. 2003 278: 17672-17679. First Published on March 13, 2003; doi:10.1074/jbc.M212890200 [Abstract] [Full Text] [PDF]  

Lýdur S. Erlendsson, Richard M. Acheson, Lars Hederstedt, and Nick E. Le Brun

Bacillus subtilis ResA Is a Thiol-Disulfide Oxidoreductase involved in Cytochrome c Synthesis
J. Biol. Chem. 2003 278: 17852-17858. First Published on March 7, 2003; doi:10.1074/jbc.M300103200 [Abstract] [Full Text] [PDF]  

Yoshinori Akiyama and Koreaki Ito

Reconstitution of Membrane Proteolysis by FtsH
J. Biol. Chem. 2003 278: 18146-18153. First Published on March 17, 2003; doi:10.1074/jbc.M302152200 [Abstract] [Full Text] [PDF]  

Limei Yan, Angus C. Nairn, H. Clive Palfrey, and Matthew J. Brady

Glucose Regulates EF-2 Phosphorylation and Protein Translation by a Protein Phosphatase-2A-dependent Mechanism in INS-1-derived 832/13 Cells
J. Biol. Chem. 2003 278: 18177-18183. First Published on March 18, 2003; doi:10.1074/jbc.M301116200 [Abstract] [Full Text] [PDF]  

Olga V. Skabkina, Maxim A. Skabkin, Nadezhda V. Popova, Dmitry N. Lyabin, Luiz O. Penalva, and Lev P. Ovchinnikov

Poly(A)-binding Protein Positively Affects YB-1 mRNA Translation through Specific Interaction with YB-1 mRNA
J. Biol. Chem. 2003 278: 18191-18198. First Published on March 19, 2003; doi:10.1074/jbc.M209073200 [Abstract] [Full Text] [PDF]  

Haiping Mao, Fanghong Li, Kathleen Ruchalski, Dick D. Mosser, John H. Schwartz, Yihan Wang, and Steven C. Borkan

hsp72 Inhibits Focal Adhesion Kinase Degradation in ATP-depleted Renal Epithelial Cells
J. Biol. Chem. 2003 278: 18214-18220. First Published on February 28, 2003; doi:10.1074/jbc.M300126200 [Abstract] [Full Text] [PDF]  

Mat Leighton and Karl E. Kadler

Paired Basic/Furin-like Proprotein Convertase Cleavage of Pro-BMP-1 in the trans-Golgi Network
J. Biol. Chem. 2003 278: 18478-18484. First Published on March 11, 2003; doi:10.1074/jbc.M213021200 [Abstract] [Full Text] [PDF]  

Huizhou Fan, Christoph W. Turck, and Rik Derynck

Characterization of Growth Factor-induced Serine Phosphorylation of Tumor Necrosis Factor- Converting Enzyme and of an Alternatively Translated Polypeptide
J. Biol. Chem. 2003 278: 18617-18627. First Published on March 5, 2003; doi:10.1074/jbc.M300331200 [Abstract] [Full Text] [PDF]  

Matthew S. Rodeheffer and Gerald S. Shadel

Multiple Interactions Involving the Amino-terminal Domain of Yeast mtRNA Polymerase Determine the Efficiency of Mitochondrial Protein Synthesis
J. Biol. Chem. 2003 278: 18695-18701. First Published on March 10, 2003; doi:10.1074/jbc.M301399200 [Abstract] [Full Text] [PDF]  

Protein Structure and Folding:

Axel Mogk, Christian Schlieker, Christine Strub, Wolfgang Rist, Jimena Weibezahn, and Bernd Bukau

Roles of Individual Domains and Conserved Motifs of the AAA+ Chaperone ClpB in Oligomerization, ATP Hydrolysis, and Chaperone Activity
J. Biol. Chem. 2003 278: 17615-17624. First Published on March 6, 2003; doi:10.1074/jbc.M209686200 [Abstract] [Full Text] [PDF]  

Sampath Srisailam, Thallampuranam Krishnaswamy S. Kumar, Dakshinamurthy Rajalingam, Karuppanan Muthusamy Kathir, Hwo-Shuenn Sheu, Fuh-Jyh Jan, Pei-Chi Chao, and Chin Yu

Amyloid-like Fibril Formation in an All -Barrel Protein. PARTIALLY STRUCTURED INTERMEDIATE STATE(S) IS A PRECURSOR FOR FIBRIL FORMATION
J. Biol. Chem. 2003 278: 17701-17709. First Published on February 12, 2003; doi:10.1074/jbc.M300336200 [Abstract] [Full Text] [PDF]  

Primo Pristovek, Kaushik Sengupta, Frank Löhr, Birgit Schäfer, Markus Wehland von Trebra, Heinz Rüterjans, and Frank Bernhard

Structural Analysis of the DNA-binding Domain of the Erwinia amylovora RcsB Protein and Its Interaction with the RcsAB Box
J. Biol. Chem. 2003 278: 17752-17759. First Published on March 5, 2003; doi:10.1074/jbc.M301328200 [Abstract] [Full Text] [PDF]  

Zhi-Song Qiao, Cheng-Yin Min, Qing-Xin Hua, Michael A. Weiss, and You-Min Feng

In Vitro Refolding of Human Proinsulin. KINETIC INTERMEDIATES, PUTATIVE DISULFIDE-FORMING PATHWAY, FOLDING INITIATION SITE, AND POTENTIAL ROLE OF C-PEPTIDE IN FOLDING PROCESS
J. Biol. Chem. 2003 278: 17800-17809. First Published on March 6, 2003; doi:10.1074/jbc.M300906200 [Abstract] [Full Text] [PDF]  

John H. Shand, James Beattie, Hyuk Song, Kirsten Phillips, Sharon M. Kelly, David J. Flint, and Gordon J. Allan

Specific Amino Acid Substitutions Determine the Differential Contribution of the N- and C-terminal Domains of Insulin-like Growth Factor (IGF)-binding Protein-5 in Binding IGF-I
J. Biol. Chem. 2003 278: 17859-17866. First Published on March 7, 2003; doi:10.1074/jbc.M300526200 [Abstract] [Full Text] [PDF]  

Mary M. Migliorini, Evan H. Behre, Shelesa Brew, Kenneth C. Ingham, and Dudley K. Strickland

Allosteric Modulation of Ligand Binding to Low Density Lipoprotein Receptor-related Protein by the Receptor-associated Protein Requires Critical Lysine Residues within Its Carboxyl-terminal Domain
J. Biol. Chem. 2003 278: 17986-17992. First Published on March 12, 2003; doi:10.1074/jbc.M212592200 [Abstract] [Full Text] [PDF]  

Sandrine Ollagnier-de Choudens, Laurence Nachin, Yiannis Sanakis, Laurent Loiseau, Frédéric Barras, and Marc Fontecave

SufA from Erwinia chrysanthemi. CHARACTERIZATION OF A SCAFFOLD PROTEIN REQUIRED FOR IRON-SULFUR CLUSTER ASSEMBLY
J. Biol. Chem. 2003 278: 17993-18001. First Published on March 12, 2003; doi:10.1074/jbc.M300285200 [Abstract] [Full Text] [PDF]  

Thusnelda Stromer, Monika Ehrnsperger, Matthias Gaestel, and Johannes Buchner

Analysis of the Interaction of Small Heat Shock Proteins with Unfolding Proteins
J. Biol. Chem. 2003 278: 18015-18021. First Published on March 12, 2003; doi:10.1074/jbc.M301640200 [Abstract] [Full Text] [PDF]  

Sau-Ching Wu, Francis J. Castellino, and Sui-Lam Wong

A Fast-acting, Modular-structured Staphylokinase Fusion with Kringle-1 from Human Plasminogen as the Fibrin-targeting Domain Offers Improved Clot Lysis Efficacy
J. Biol. Chem. 2003 278: 18199-18206. First Published on March 19, 2003; doi:10.1074/jbc.M210919200 [Abstract] [Full Text] [PDF]  

Sushmita Singh and Adam Zlotnick

Observed Hysteresis of Virus Capsid Disassembly Is Implicit in Kinetic Models of Assembly
J. Biol. Chem. 2003 278: 18249-18255. First Published on March 13, 2003; doi:10.1074/jbc.M211408200 [Abstract] [Full Text] [PDF]  

Almerinda Di Venere, Maria Luisa Salucci, Guus van Zadelhoff, Gerrit Veldink, Giampiero Mei, Nicola Rosato, Alessandro Finazzi-Agrò, and Mauro Maccarrone

Structure-to-Function Relationship of Mini-Lipoxygenase, a 60-kDa Fragment of Soybean Lipoxygenase-1 with Lower Stability but Higher Enzymatic Activity
J. Biol. Chem. 2003 278: 18281-18288. First Published on March 7, 2003; doi:10.1074/jbc.M212122200 [Abstract] [Full Text] [PDF]  

Carsten Müller, Susanne Richter, and Ursula Rinas

Kinetics Control Preferential Heterodimer Formation of Platelet-derived Growth Factor from Unfolded A- and B-chains
J. Biol. Chem. 2003 278: 18330-18335. First Published on March 3, 2003; doi:10.1074/jbc.M212317200 [Abstract] [Full Text] [PDF]  

Gabriele Schramm, Franco H. Falcone, Achim Gronow, Karin Haisch, Uwe Mamat, Michael J. Doenhoff, Guilherme Oliveira, Jürgen Galle, Clemens A. Dahinden, and Helmut Haas

Molecular Characterization of an Interleukin-4-inducing Factor from Schistosoma mansoni Eggs
J. Biol. Chem. 2003 278: 18384-18392. First Published on March 6, 2003; doi:10.1074/jbc.M300497200 [Abstract] [Full Text] [PDF]  

Stefan Steinbacher, Johannes Kaiser, Wolfgang Eisenreich, Robert Huber, Adelbert Bacher, and Felix Rohdich

Structural Basis of Fosmidomycin Action Revealed by the Complex with 2-C-Methyl-D-erythritol 4-phosphate Synthase (IspC). IMPLICATIONS FOR THE CATALYTIC MECHANISM AND ANTI-MALARIA DRUG DEVELOPMENT
J. Biol. Chem. 2003 278: 18401-18407. First Published on March 5, 2003; doi:10.1074/jbc.M300993200 [Abstract] [Full Text] [PDF]  

Jocelyne Vreede, Michael A. van der Horst, Klaas J. Hellingwerf, Wim Crielaard, and Daan M. F. van Aalten

PAS Domains. COMMON STRUCTURE AND COMMON FLEXIBILITY
J. Biol. Chem. 2003 278: 18434-18439. First Published on March 14, 2003; doi:10.1074/jbc.M301701200 [Abstract] [Full Text] [PDF]  

Christian Mellwig and Bettina Böttcher

A Unique Resting Position of the ATP-synthase from Chloroplasts
J. Biol. Chem. 2003 278: 18544-18549. First Published on March 6, 2003; doi:10.1074/jbc.M212852200 [Abstract] [Full Text] [PDF]  

Kuppan Gokulan, Bernhard Rupp, Martin S. Pavelka, Jr., William R. Jacobs, Jr., and James C. Sacchettini

Crystal Structure of Mycobacterium tuberculosis Diaminopimelate Decarboxylase, an Essential Enzyme in Bacterial Lysine Biosynthesis
J. Biol. Chem. 2003 278: 18588-18596. First Published on March 10, 2003; doi:10.1074/jbc.M301549200 [Abstract] [Full Text] [PDF]  

Sonia Longhi, Véronique Receveur-Bréchot, David Karlin, Kenth Johansson, Hervé Darbon, David Bhella, Robert Yeo, Stéphanie Finet, and Bruno Canard

The C-terminal Domain of the Measles Virus Nucleoprotein Is Intrinsically Disordered and Folds upon Binding to the C-terminal Moiety of the Phosphoprotein
J. Biol. Chem. 2003 278: 18638-18648. First Published on March 5, 2003; doi:10.1074/jbc.M300518200 [Abstract] [Full Text] [PDF]  

Enzyme Catalysis and Regulation:

Shenmin Yin, C. Kiong Ho, and Stewart Shuman

Structure-Function Analysis of T4 RNA Ligase 2
J. Biol. Chem. 2003 278: 17601-17608. First Published on February 27, 2003; doi:10.1074/jbc.M300817200 [Abstract] [Full Text] [PDF]  

Hirotaka Kitada, Masaaki Miyata, Toshifumi Nakamura, Aki Tozawa, Wataru Honma, Miki Shimada, Kiyoshi Nagata, Christopher J. Sinal, Grace L. Guo, Frank J. Gonzalez, and Yasushi Yamazoe

Protective Role of Hydroxysteroid Sulfotransferase in Lithocholic Acid-induced Liver Toxicity
J. Biol. Chem. 2003 278: 17838-17844. First Published on March 7, 2003; doi:10.1074/jbc.M210634200 [Abstract] [Full Text] [PDF]  

Jeffrey W. Schertzer and Eric D. Brown

Purified, Recombinant TagF Protein from Bacillus subtilis 168 Catalyzes the Polymerization of Glycerol Phosphate onto a Membrane Acceptor in Vitro
J. Biol. Chem. 2003 278: 18002-18007. First Published on March 12, 2003; doi:10.1074/jbc.M300706200 [Abstract] [Full Text] [PDF]  

Jing Wu and Ronald W. Woodard

Escherichia coli YrbI Is 3-Deoxy-D-manno-octulosonate 8-Phosphate Phosphatase
J. Biol. Chem. 2003 278: 18117-18123. First Published on March 14, 2003; doi:10.1074/jbc.M301983200 [Abstract] [Full Text] [PDF]  

Janelle L. Lauer-Fields, Thilaka Sritharan, M. Sharon Stack, Hideaki Nagase, and Gregg B. Fields

Selective Hydrolysis of Triple-helical Substrates by Matrix Metalloproteinase-2 and -9
J. Biol. Chem. 2003 278: 18140-18145. First Published on March 17, 2003; doi:10.1074/jbc.M211330200 [Abstract] [Full Text] [PDF]  

Gregory A. Grant, Zhiqin Hu, and Xiao Lan Xu

Hybrid Tetramers Reveal Elements of Cooperativity in Escherichia coli D-3-Phosphoglycerate Dehydrogenase
J. Biol. Chem. 2003 278: 18170-18176. First Published on March 18, 2003; doi:10.1074/jbc.M213050200 [Abstract] [Full Text] [PDF]  

Dasantila Golemi-Kotra, Joo Young Cha, Samy O. Meroueh, Sergei B. Vakulenko, and Shahriar Mobashery

Resistance to -Lactam Antibiotics and Its Mediation by the Sensor Domain of the Transmembrane BlaR Signaling Pathway in Staphylococcus aureus
J. Biol. Chem. 2003 278: 18419-18425. First Published on February 18, 2003; doi:10.1074/jbc.M300611200 [Abstract] [Full Text] [PDF] Supplemental Data  

Steven S. Rosenfeld, Polly M. Fordyce, Geraldine M. Jefferson, Peter H. King, and Steven M. Block

Stepping and Stretching. HOW KINESIN USES INTERNAL STRAIN TO WALK PROCESSIVELY
J. Biol. Chem. 2003 278: 18550-18556. First Published on March 6, 2003; doi:10.1074/jbc.M300849200 [Abstract] [Full Text] [PDF]  

Metabolism and Bioenergetics:

Michael Levy, Guido C. Faas, Peter Saggau, William J. Craigen, and J. David Sweatt

Mitochondrial Regulation of Synaptic Plasticity in the Hippocampus
J. Biol. Chem. 2003 278: 17727-17734. First Published on February 25, 2003; doi:10.1074/jbc.M212878200 [Abstract] [Full Text] [PDF]  

Max Dolder, Bernd Walzel, Oliver Speer, Uwe Schlattner, and Theo Wallimann

Inhibition of the Mitochondrial Permeability Transition by Creatine Kinase Substrates. REQUIREMENT FOR MICROCOMPARTMENTATION
J. Biol. Chem. 2003 278: 17760-17766. First Published on March 5, 2003; doi:10.1074/jbc.M208705200 [Abstract] [Full Text] [PDF]  

Satinder Kaur Gidda, Otto Miersch, Anastasia Levitin, Jürgen Schmidt, Claus Wasternack, and Luc Varin

Biochemical and Molecular Characterization of a Hydroxyjasmonate Sulfotransferase from Arabidopsis thaliana
J. Biol. Chem. 2003 278: 17895-17900. First Published on March 10, 2003; doi:10.1074/jbc.M211943200 [Abstract] [Full Text] [PDF]  

Sophie Rome, Karine Clément, Rémi Rabasa-Lhoret, Emmanuelle Loizon, Christine Poitou, Greg S. Barsh, Jean-Paul Riou, Martine Laville, and Hubert Vidal

Microarray Profiling of Human Skeletal Muscle Reveals That Insulin Regulates ~800 Genes during a Hyperinsulinemic Clamp
J. Biol. Chem. 2003 278: 18063-18068. First Published on March 5, 2003; doi:10.1074/jbc.M300293200 [Abstract] [Full Text] [PDF] Supplemental Data  

Lina Du, Xiaopeng Zhang, Yong Y. Han, Nancy A. Burke, Patrick M. Kochanek, Simon C. Watkins, Steven H. Graham, Joseph A. Carcillo, Csaba Szabó, and Robert S. B. Clark

Intra-mitochondrial Poly(ADP-ribosylation) Contributes to NAD⁺ Depletion and Cell Death Induced by Oxidative Stress
J. Biol. Chem. 2003 278: 18426-18433. First Published on March 7, 2003; doi:10.1074/jbc.M301295200 [Abstract] [Full Text] [PDF]  

Glycobiology and Extracellular Matrices:

Nichola Hartigan, Laure Garrigue-Antar, and Karl E. Kadler

Bone Morphogenetic Protein-1 (BMP-1). IDENTIFICATION OF THE MINIMAL DOMAIN STRUCTURE FOR PROCOLLAGEN C-PROTEINASE ACTIVITY
J. Biol. Chem. 2003 278: 18045-18049. First Published on March 13, 2003; doi:10.1074/jbc.M211448200 [Abstract] [Full Text] [PDF]  

Paul G. Scott, J. Günter Grossmann, Carole M. Dodd, John K. Sheehan, and Paul N. Bishop

Light and X-ray Scattering Show Decorin to Be a Dimer in Solution
J. Biol. Chem. 2003 278: 18353-18359. First Published on February 21, 2003; doi:10.1074/jbc.M211936200 [Abstract] [Full Text] [PDF]  

Beth A. Kozel, Hiroshi Wachi, Elaine C. Davis, and Robert P. Mecham

Domains in Tropoelastin That Mediate Elastin Deposition in Vitro and in Vivo
J. Biol. Chem. 2003 278: 18491-18498. First Published on March 6, 2003; doi:10.1074/jbc.M212715200 [Abstract] [Full Text] [PDF]  

Lipids and Lipoproteins:

Rachel C. Williams, Mark L. Rees, Myra F. Jacobs, Zoltán Prágai, Joanne E. Thwaite, Leslie W. J. Baillie, Peter T. Emmerson, and Colin R. Harwood

Production of Bacillus anthracis Protective Antigen Is Dependent on the Extracellular Chaperone, PrsA
J. Biol. Chem. 2003 278: 18056-18062. First Published on February 26, 2003; doi:10.1074/jbc.M301244200 [Abstract] [Full Text] [PDF]  

Gilles Ferry, Edwige Tellier, Anne Try, Sandra Grés, Isabelle Naime, Marie Françoise Simon, Marianne Rodriguez, Jérémie Boucher, Ivan Tack, Stéphane Gesta, Pascale Chomarat, Marc Dieu, Martine Raes, Jean Pierre Galizzi, Philippe Valet, Jean A. Boutin, and Jean Sébastien Saulnier-Blache

Autotaxin Is Released from Adipocytes, Catalyzes Lysophosphatidic Acid Synthesis, and Activates Preadipocyte Proliferation. UP-REGULATED EXPRESSION WITH ADIPOCYTE DIFFERENTIATION AND OBESITY
J. Biol. Chem. 2003 278: 18162-18169. First Published on March 17, 2003; doi:10.1074/jbc.M301158200 [Abstract] [Full Text] [PDF]  

Marc-Estienne Roehrich, Vincent Mooser, Vincent Lenain, Joachim Herz, Johannes Nimpf, Salman Azhar, Martine Bideau, Alessandro Capponi, Pascal Nicod, Jacques-Antoine Haefliger, and Gérard Waeber

Insulin-secreting -Cell Dysfunction Induced by Human Lipoproteins
J. Biol. Chem. 2003 278: 18368-18375. First Published on February 18, 2003; doi:10.1074/jbc.M300102200 [Abstract] [Full Text] [PDF]  

Chi-Liang Eric Yen and Robert V. Farese, Jr.

MGAT2, a Monoacylglycerol Acyltransferase Expressed in the Small Intestine
J. Biol. Chem. 2003 278: 18532-18537. First Published on March 5, 2003; doi:10.1074/jbc.M301633200 [Abstract] [Full Text] [PDF]  

Membrane Transport Structure Function and Biogenesis:

Peter R. Wielinga, Ingrid van der Heijden, Glen Reid, Jos H. Beijnen, Jan Wijnholds, and Piet Borst

Characterization of the MRP4- and MRP5-mediated Transport of Cyclic Nucleotides from Intact Cells
J. Biol. Chem. 2003 278: 17664-17671. First Published on March 13, 2003; doi:10.1074/jbc.M212723200 [Abstract] [Full Text] [PDF]  

Richard D. Whitlow, Ayelet Sacher, Donald D. F. Loo, Nathan Nelson, and Sepehr Eskandari

The Anticonvulsant Valproate Increases the Turnover Rate of -Aminobutyric Acid Transporters
J. Biol. Chem. 2003 278: 17716-17726. First Published on February 20, 2003; doi:10.1074/jbc.M207582200 [Abstract] [Full Text] [PDF]  

Morten J. Buch-Pedersen and Michael G. Palmgren

Conserved Asp⁶⁸⁴ in Transmembrane Segment M6 of the Plant Plasma Membrane P-type Proton Pump AHA2 Is a Molecular Determinant of Proton Translocation
J. Biol. Chem. 2003 278: 17845-17851. First Published on March 7, 2003; doi:10.1074/jbc.M212729200 [Abstract] [Full Text] [PDF]  

Andrew N. Stephens, Muhammad A. Khan, Xavier Roucou, Phillip Nagley, and Rodney J. Devenish

The Molecular Neighborhood of Subunit 8 of Yeast Mitochondrial F₁F₀-ATP Synthase Probed by Cysteine Scanning Mutagenesis and Chemical Modification
J. Biol. Chem. 2003 278: 17867-17875. First Published on March 7, 2003; doi:10.1074/jbc.M300967200 [Abstract] [Full Text] [PDF]  

Wenyan Niu, Carol Huang, Zafar Nawaz, Michelle Levy, Romel Somwar, Dailin Li, Philip J. Bilan, and Amira Klip

Maturation of the Regulation of GLUT4 Activity by p38 MAPK during L6 Cell Myogenesis
J. Biol. Chem. 2003 278: 17953-17962. First Published on March 11, 2003; doi:10.1074/jbc.M211136200 [Abstract] [Full Text] [PDF]  

Emmanuel Coeytaux, Dominique Coulaud, Eric Le Cam, Olivier Danos, and Antoine Kichler

The Cationic Amphipathic -Helix of HIV-1 Viral Protein R (Vpr) Binds to Nucleic Acids, Permeabilizes Membranes, and Efficiently Transfects Cells
J. Biol. Chem. 2003 278: 18110-18116. First Published on March 14, 2003; doi:10.1074/jbc.M300248200 [Abstract] [Full Text] [PDF]  

Nazli Maki, Peter Hafkemeyer, and Saibal Dey

Allosteric Modulation of Human P-glycoprotein. INHIBITION OF TRANSPORT BY PREVENTING SUBSTRATE TRANSLOCATION AND DISSOCIATION
J. Biol. Chem. 2003 278: 18132-18139. First Published on March 17, 2003; doi:10.1074/jbc.M210413200 [Abstract] [Full Text] [PDF]  

Ricardo P. Souto, Gino Vallega, Jonathan Wharton, Jorgen Vinten, Jorgen Tranum-Jensen, and Paul F. Pilch

Immunopurification and Characterization of Rat Adipocyte Caveolae Suggest Their Dissociation from Insulin Signaling
J. Biol. Chem. 2003 278: 18321-18329. First Published on March 11, 2003; doi:10.1074/jbc.M211541200 [Abstract] [Full Text] [PDF]  

Michael C. Chicka and Emanuel E. Strehler

Alternative Splicing of the First Intracellular Loop of Plasma Membrane Ca²⁺-ATPase Isoform 2 Alters Its Membrane Targeting
J. Biol. Chem. 2003 278: 18464-18470. First Published on March 6, 2003; doi:10.1074/jbc.M301482200 [Abstract] [Full Text] [PDF]  

Olga Vitavska, Helmut Wieczorek, and Hans Merzendorfer

A Novel Role for Subunit C in Mediating Binding of the H⁺-V-ATPase to the Actin Cytoskeleton
J. Biol. Chem. 2003 278: 18499-18505. First Published on February 25, 2003; doi:10.1074/jbc.M212844200 [Abstract] [Full Text] [PDF]  

Sabine Gilch, Franziska Wopfner, Ingrid Renner-Müller, Elisabeth Kremmer, Christine Bauer, Eckhard Wolf, Gottfried Brem, Martin H. Groschup, and Hermann M. Schätzl

Polyclonal Anti-PrP Auto-antibodies Induced with Dimeric PrP Interfere Efficiently with PrP^Sc Propagation in Prion-infected Cells
J. Biol. Chem. 2003 278: 18524-18531. First Published on March 11, 2003; doi:10.1074/jbc.M210723200 [Abstract] [Full Text] [PDF]  

John J. Flanagan, Jui-Chang Chen, Yiwei Miao, Yuanlong Shao, Jialing Lin, Paul E. Bock, and Arthur E. Johnson

Signal Recognition Particle Binds to Ribosome-bound Signal Sequences with Fluorescence-detected Subnanomolar Affinity That Does Not Diminish as the Nascent Chain Lengthens
J. Biol. Chem. 2003 278: 18628-18637. First Published on March 5, 2003; doi:10.1074/jbc.M300173200 [Abstract] [Full Text] [PDF]  

Mechanisms Of Signal Transduction:

Shigang Xiong, Hongyun She, Heigo Takeuchi, Bora Han, John F. Engelhardt, C. H. Barton, Ebrahim Zandi, Cecilia Giulivi, and Hidekazu Tsukamoto

Signaling Role of Intracellular Iron in NF-B Activation
J. Biol. Chem. 2003 278: 17646-17654. First Published on March 11, 2003; doi:10.1074/jbc.M210905200 [Abstract] [Full Text] [PDF]  

Chuan Yin Liu, Zhaohui Xu, and Randal J. Kaufman

Structure and Intermolecular Interactions of the Luminal Dimerization Domain of Human IRE1
J. Biol. Chem. 2003 278: 17680-17687. First Published on March 13, 2003; doi:10.1074/jbc.M300418200 [Abstract] [Full Text] [PDF]  

Yoonseong Park, Young-Joon Kim, Vincent Dupriez, and Michael E. Adams

Two Subtypes of Ecdysis-triggering Hormone Receptor in Drosophila melanogaster
J. Biol. Chem. 2003 278: 17710-17715. First Published on February 13, 2003; doi:10.1074/jbc.M301119200 [Abstract] [Full Text] [PDF]  

Timm Westhoff, Joachim Jankowski, Sven Schmidt, Jiankai Luo, Günter Giebing, Hartmut Schlüter, Martin Tepel, Walter Zidek, and Markus van der Giet

Identification and Characterization of Adenosine 5'-Tetraphosphate in Human Myocardial Tissue
J. Biol. Chem. 2003 278: 17735-17740. First Published on February 27, 2003; doi:10.1074/jbc.M300288200 [Abstract] [Full Text] [PDF]  

Maureen K. Bunger, Susan M. Moran, Edward Glover, Tami L. Thomae, Garet P. Lahvis, Bernice C. Lin, and Christopher A. Bradfield

Resistance to 2,3,7,8-Tetrachlorodibenzo-p-dioxin Toxicity and Abnormal Liver Development in Mice Carrying a Mutation in the Nuclear Localization Sequence of the Aryl Hydrocarbon Receptor
J. Biol. Chem. 2003 278: 17767-17774. First Published on March 5, 2003; doi:10.1074/jbc.M209594200 [Abstract] [Full Text] [PDF]  

Andrew Macdonald, Katherine Crowder, Andrew Street, Christopher McCormick, Kalle Saksela, and Mark Harris

The Hepatitis C Virus Non-structural NS5A Protein Inhibits Activating Protein-1 Function by Perturbing Ras-ERK Pathway Signaling
J. Biol. Chem. 2003 278: 17775-17784. First Published on March 5, 2003; doi:10.1074/jbc.M210900200 [Abstract] [Full Text] [PDF]  

Ulrich Beuers, Gerald U. Denk, Carol J. Soroka, Ralf Wimmer, Christian Rust, Gustav Paumgartner, and James L. Boyer

Taurolithocholic Acid Exerts Cholestatic Effects via Phosphatidylinositol 3-Kinase-dependent Mechanisms in Perfused Rat Livers and Rat Hepatocyte Couplets
J. Biol. Chem. 2003 278: 17810-17818. First Published on March 7, 2003; doi:10.1074/jbc.M209898200 [Abstract] [Full Text] [PDF]  

Wolf Oehrl, Ignacio Rubio, and Reinhard Wetzker

Serine 338 Phosphorylation Is Dispensable for Activation of c-Raf1
J. Biol. Chem. 2003 278: 17819-17826. First Published on March 7, 2003; doi:10.1074/jbc.M209951200 [Abstract] [Full Text] [PDF]  

Moulay Driss Rochdi and Jean-Luc Parent

G_q-coupled Receptor Internalization Specifically Induced by G_q Signaling. REGULATION BY EBP50
J. Biol. Chem. 2003 278: 17827-17837. First Published on March 7, 2003; doi:10.1074/jbc.M210319200 [Abstract] [Full Text] [PDF]  

Kimberly M. Baker, Guo Wei, Alicia Erbe Schaffner, and Michael C. Ostrowski

Ets-2 and Components of Mammalian SWI/SNF Form a Repressor Complex That Negatively Regulates the BRCA1 Promoter
J. Biol. Chem. 2003 278: 17876-17884. First Published on March 10, 2003; doi:10.1074/jbc.M209480200 [Abstract] [Full Text] [PDF]  

Linan Ha, Susan Ceryak, and Steven R. Patierno

Chromium (VI) Activates Ataxia Telangiectasia Mutated (ATM) Protein. REQUIREMENT OF ATM FOR BOTH APOPTOSIS AND RECOVERY FROM TERMINAL GROWTH ARREST
J. Biol. Chem. 2003 278: 17885-17894. First Published on March 10, 2003; doi:10.1074/jbc.M210560200 [Abstract] [Full Text] [PDF]  

Karim Sabrane, Stepan Gambaryan, Ralf P. Brandes, Rita Holtwick, Melanie Voss, and Michaela Kuhn

Increased Sensitivity to Endothelial Nitric Oxide (NO) Contributes to Arterial Normotension in Mice with Vascular Smooth Muscle-selective Deletion of the Atrial Natriuretic Peptide (ANP) Receptor
J. Biol. Chem. 2003 278: 17963-17968. First Published on March 11, 2003; doi:10.1074/jbc.M213113200 [Abstract] [Full Text] [PDF]  

Peter Storz, Heike Döppler, Franz-Josef Johannes, and Alex Toker

Tyrosine Phosphorylation of Protein Kinase D in the Pleckstrin Homology Domain Leads to Activation
J. Biol. Chem. 2003 278: 17969-17976. First Published on March 11, 2003; doi:10.1074/jbc.M213224200 [Abstract] [Full Text] [PDF]  

Noriyuki Hatae, Ayumi Kita, Satoshi Tanaka, Yukihiko Sugimoto, and Atsushi Ichikawa

Induction of Adherent Activity in Mastocytoma P-815 Cells by the Cooperation of Two Prostaglandin E₂ Receptor Subtypes, EP3 and EP4
J. Biol. Chem. 2003 278: 17977-17981. First Published on March 11, 2003; doi:10.1074/jbc.M301312200 [Abstract] [Full Text] [PDF]  

Maria Chiara Deregibus, Stefano Buttiglieri, Simona Russo, Benedetta Bussolati, and Giovanni Camussi

CD40-dependent Activation of Phosphatidylinositol 3-Kinase/Akt Pathway Mediates Endothelial Cell Survival and in Vitro Angiogenesis
J. Biol. Chem. 2003 278: 18008-18014. First Published on March 12, 2003; doi:10.1074/jbc.M300711200 [Abstract] [Full Text] [PDF]  

Gary M. Wildey, Supriya Patil, and Philip H. Howe

Smad3 Potentiates Transforming Growth Factor (TGF)-induced Apoptosis and Expression of the BH3-only Protein Bim in WEHI 231 B Lymphocytes
J. Biol. Chem. 2003 278: 18069-18077. First Published on March 13, 2003; doi:10.1074/jbc.M211958200 [Abstract] [Full Text] [PDF]  

Sonoko Hirayama, Reiko Sugiura, Yabin Lu, Takuya Maeda, Kenji Kawagishi, Mistuhiro Yokoyama, Hideki Tohda, Yuko Giga-Hama, Hisato Shuntoh, and Takayoshi Kuno

Zinc Finger Protein Prz1 Regulates Ca²⁺ but Not Cl Homeostasis in Fission Yeast. IDENTIFICATION OF DISTINCT BRANCHES OF CALCINEURIN SIGNALING PATHWAY IN FISSION YEAST
J. Biol. Chem. 2003 278: 18078-18084. First Published on March 13, 2003; doi:10.1074/jbc.M212900200 [Abstract] [Full Text] [PDF]  

Costas Mitsopoulos, Ceniz Zihni, Ritu Garg, Anne J. Ridley, and Jonathan D. H. Morris

The Prostate-derived Sterile 20-like Kinase (PSK) Regulates Microtubule Organization and Stability
J. Biol. Chem. 2003 278: 18085-18091. First Published on March 13, 2003; doi:10.1074/jbc.M213064200 [Abstract] [Full Text] [PDF]  

Penny Clarke, Suzanne M. Meintzer, Lisa A. Moffitt, and Kenneth L. Tyler

Two Distinct Phases of Virus-induced Nuclear Factor B Regulation Enhance Tumor Necrosis Factor-related Apoptosis-inducing Ligand-mediated Apoptosis in Virus-infected Cells
J. Biol. Chem. 2003 278: 18092-18100. First Published on March 13, 2003; doi:10.1074/jbc.M300265200 [Abstract] [Full Text] [PDF]  

Daniel Kerschensteiner, Francisco Monje, and Martin Stocker

Structural Determinants of the Regulation of the Voltage-gated Potassium Channel Kv2.1 by the Modulatory -Subunit Kv9.3
J. Biol. Chem. 2003 278: 18154-18161. First Published on March 17, 2003; doi:10.1074/jbc.M213117200 [Abstract] [Full Text] [PDF]  

Il Ho Jang, Sukmook Lee, Jong Bae Park, Jong Hyun Kim, Chang Sup Lee, Eun-Mi Hur, Il Shin Kim, Kyong-Tai Kim, Hitoshi Yagisawa, Pann-Ghill Suh, and Sung Ho Ryu

The Direct Interaction of Phospholipase C-1 with Phospholipase D2 Is Important for Epidermal Growth Factor Signaling
J. Biol. Chem. 2003 278: 18184-18190. First Published on March 19, 2003; doi:10.1074/jbc.M208438200 [Abstract] [Full Text] [PDF]  

Sarah A. Walter, Richard E. Cutler, Jr., Ricardo Martinez, Mikhail Gishizky, and Ronald J. Hill

Stk10, a New Member of the Polo-like Kinase Kinase Family Highly Expressed in Hematopoietic Tissue
J. Biol. Chem. 2003 278: 18221-18228. First Published on March 13, 2003; doi:10.1074/jbc.M212556200 [Abstract] [Full Text] [PDF]  

Kojiro Nagai, Hidenori Arai, Motoko Yanagita, Takeshi Matsubara, Hiroshi Kanamori, Toru Nakano, Noriyuki Iehara, Atsushi Fukatsu, Toru Kita, and Toshio Doi

Growth Arrest-specific Gene 6 Is Involved in Glomerular Hypertrophy in the Early Stage of Diabetic Nephropathy
J. Biol. Chem. 2003 278: 18229-18234. First Published on March 17, 2003; doi:10.1074/jbc.M213266200 [Abstract] [Full Text] [PDF]  

Christopher M. Schonhoff, Benjamin Gaston, and Joan B. Mannick

Nitrosylation of Cytochrome c during Apoptosis
J. Biol. Chem. 2003 278: 18265-18270. First Published on March 19, 2003; doi:10.1074/jbc.M212459200 [Abstract] [Full Text] [PDF]  

Alison Burkart, Babak Samii, Silvia Corvera, and Howard S. Shpetner

Regulation of the SHP-2 Tyrosine Phosphatase by a Novel Cholesterol- and Cell Confluence-dependent Mechanism
J. Biol. Chem. 2003 278: 18360-18367. First Published on February 27, 2003; doi:10.1074/jbc.M210701200 [Abstract] [Full Text] [PDF] Supplemental Data  

Megan E. Cavet, Stephanie Lehoux, and Bradford C. Berk

14-3-3 Is a p90 Ribosomal S6 Kinase (RSK) Isoform 1-binding Protein That Negatively Regulates RSK Kinase Activity
J. Biol. Chem. 2003 278: 18376-18383. First Published on March 4, 2003; doi:10.1074/jbc.M208475200 [Abstract] [Full Text] [PDF]  

Kent L. Rossman, Li Cheng, Gwendolyn M. Mahon, Rafael J. Rojas, Jason T. Snyder, Ian P. Whitehead, and John Sondek

Multifunctional Roles for the PH Domain of Dbs in Regulating Rho GTPase Activation
J. Biol. Chem. 2003 278: 18393-18400. First Published on March 13, 2003; doi:10.1074/jbc.M300127200 [Abstract] [Full Text] [PDF]  

Nanao Horike, Hiroshi Takemori, Yoshiko Katoh, Junko Doi, Li Min, Tomoichiro Asano, Xiao Jian Sun, Hiroyasu Yamamoto, Soji Kasayama, Masaaki Muraoka, Yasuki Nonaka, and Mitsuhiro Okamoto

Adipose-specific Expression, Phosphorylation of Ser⁷⁹⁴ in Insulin Receptor Substrate-1, and Activation in Diabetic Animals of Salt-inducible Kinase-2
J. Biol. Chem. 2003 278: 18440-18447. First Published on March 6, 2003; doi:10.1074/jbc.M211770200 [Abstract] [Full Text] [PDF]  

Mayumi Shindo, Kazuhiro Irie, Akiko Masuda, Hajime Ohigashi, Yasuhito Shirai, Kei Miyasaka, and Naoaki Saito

Synthesis and Phorbol Ester Binding of the Cysteine-rich Domains of Diacylglycerol Kinase (DGK) Isozymes. DGK AND DGK ARE NEW TARGETS OF TUMOR-PROMOTING PHORBOL ESTERS
J. Biol. Chem. 2003 278: 18448-18454. First Published on March 5, 2003; doi:10.1074/jbc.M300400200 [Abstract] [Full Text] [PDF]  

Jun Ninomiya-Tsuji, Taisuke Kajino, Koichiro Ono, Toshihiko Ohtomo, Masahiko Matsumoto, Masashi Shiina, Masahiko Mihara, Masayuki Tsuchiya, and Kunihiro Matsumoto

A Resorcylic Acid Lactone, 5Z-7-Oxozeaenol, Prevents Inflammation by Inhibiting the Catalytic Activity of TAK1 MAPK Kinase Kinase
J. Biol. Chem. 2003 278: 18485-18490. First Published on March 6, 2003; doi:10.1074/jbc.M207453200 [Abstract] [Full Text] [PDF]  

Christine McDonald, Panayiotis O. Vacratsis, James B. Bliska, and Jack E. Dixon

The Yersinia Virulence Factor YopM Forms a Novel Protein Complex with Two Cellular Kinases
J. Biol. Chem. 2003 278: 18514-18523. First Published on March 6, 2003; doi:10.1074/jbc.M301226200 [Abstract] [Full Text] [PDF]  

Koh-ichi Nagata, Aie Kawajiri, Seiya Matsui, Mihoko Takagishi, Takashi Shiromizu, Noriko Saitoh, Ichiro Izawa, Tohru Kiyono, Tomohiko J. Itoh, Hirokazu Hotani, and Masaki Inagaki

Filament Formation of MSF-A, a Mammalian Septin, in Human Mammary Epithelial Cells Depends on Interactions with Microtubules
J. Biol. Chem. 2003 278: 18538-18543. First Published on March 6, 2003; doi:10.1074/jbc.M205246200 [Abstract] [Full Text] [PDF]  

Hyunil Ha, Han Bok Kwak, Seung Ku Lee, Doe Sun Na, Christopher E. Rudd, Zang Hee Lee, and Hong-Hee Kim

Membrane Rafts Play a Crucial Role in Receptor Activator of Nuclear Factor B Signaling and Osteoclast Function
J. Biol. Chem. 2003 278: 18573-18580. First Published on March 11, 2003; doi:10.1074/jbc.M212626200 [Abstract] [Full Text] [PDF]  

Rosa Fayos, Giuseppe Melacini, Marceen G. Newlon, Lora Burns, John D. Scott, and Patricia A. Jennings

Induction of Flexibility through Protein-Protein Interactions
J. Biol. Chem. 2003 278: 18581-18587. First Published on February 25, 2003; doi:10.1074/jbc.M300866200 [Abstract] [Full Text] [PDF]  

Sayaka Takemoto-Kimura, Hisashi Terai, Maki Takamoto, Shogo Ohmae, Shoko Kikumura, Eri Segi, Yoshiki Arakawa, Tomoyuki Furuyashiki, Shuh Narumiya, and Haruhiko Bito

Molecular Cloning and Characterization of CLICK-III/CaMKI, a Novel Membrane-anchored Neuronal Ca²⁺/Calmodulin-dependent Protein Kinase (CaMK)
J. Biol. Chem. 2003 278: 18597-18605. First Published on March 11, 2003; doi:10.1074/jbc.M300578200 [Abstract] [Full Text] [PDF]  

Kah Fei Wan, Balwinder S. Sambi, Rothwelle Tate, Catherine Waters, and Nigel J. Pyne

The Inhibitory Subunit of the Type 6 Retinal cGMP Phosphodiesterase Functions to Link c-Src and G-protein-coupled Receptor Kinase 2 in a Signaling Unit That Regulates p42/p44 Mitogen-activated Protein Kinase by Epidermal Growth Factor
J. Biol. Chem. 2003 278: 18658-18663. First Published on March 6, 2003; doi:10.1074/jbc.M212103200 [Abstract] [Full Text] [PDF]  

Roumen Pankov, Edna Cukierman, Katherine Clark, Kazue Matsumoto, Cornelia Hahn, Benoit Poulin, and Kenneth M. Yamada

Specific ₁ Integrin Site Selectively Regulates Akt/Protein Kinase B Signaling via Local Activation of Protein Phosphatase 2A
J. Biol. Chem. 2003 278: 18671-18681. First Published on March 11, 2003; doi:10.1074/jbc.M300879200 [Abstract] [Full Text] [PDF]  

Scott J. Cameron, Sundeep Malik, Masashi Akaike, Nicole Lerner-Marmarosh, Chen Yan, Jiing-Dwan Lee, Jun-ichi Abe, and Jay Yang

Regulation of Epidermal Growth Factor-induced Connexin 43 Gap Junction Communication by Big Mitogen-activated Protein Kinase 1/ERK5 but Not ERK1/2 Kinase Activation
J. Biol. Chem. 2003 278: 18682-18688. First Published on March 12, 2003; doi:10.1074/jbc.M213283200 [Abstract] [Full Text] [PDF]  

Molecular Basis Of Cell and Developmental Biology:

Yasuhiko Kamikubo, Akifumi Takaori-Kondo, Takashi Uchiyama, and Toshiyuki Hori

Inhibition of Cell Growth by Conditional Expression of kpm, a Human Homologue of Drosophila warts/lats Tumor Suppressor
J. Biol. Chem. 2003 278: 17609-17614. First Published on March 5, 2003; doi:10.1074/jbc.M211974200 [Abstract] [Full Text] [PDF]  

Yoshihiko Yamakita, Fumio Oosawa, Shigeko Yamashiro, and Fumio Matsumura

Caldesmon Inhibits Arp2/3-mediated Actin Nucleation
J. Biol. Chem. 2003 278: 17937-17944. First Published on March 11, 2003; doi:10.1074/jbc.M208739200 [Abstract] [Full Text] [PDF]  

Katrien Van Impe, Veerle De Corte, Ludwig Eichinger, Erik Bruyneel, Marc Mareel, Joël Vandekerckhove, and Jan Gettemans

The Nucleo-cytoplasmic Actin-binding Protein CapG Lacks a Nuclear Export Sequence Present in Structurally Related Proteins
J. Biol. Chem. 2003 278: 17945-17952. First Published on March 11, 2003; doi:10.1074/jbc.M209946200 [Abstract] [Full Text] [PDF]  

Kerstin Wolk, Stefanie Kunz, Nigel E. A. Crompton, Hans-Dieter Volk, and Robert Sabat

Multiple Mechanisms of Reduced Major Histocompatibility Complex Class II Expression in Endotoxin Tolerance
J. Biol. Chem. 2003 278: 18030-18036. First Published on March 13, 2003; doi:10.1074/jbc.M207714200 [Abstract] [Full Text] [PDF]  

Janet R. Sparrow, Heidi R. Vollmer-Snarr, Jilin Zhou, Young P. Jang, Steffen Jockusch, Yasuhiro Itagaki, and Koji Nakanishi

A2E-epoxides Damage DNA in Retinal Pigment Epithelial Cells. VITAMIN E AND OTHER ANTIOXIDANTS INHIBIT A2E-EPOXIDE FORMATION
J. Biol. Chem. 2003 278: 18207-18213. First Published on March 19, 2003; doi:10.1074/jbc.M300457200 [Abstract] [Full Text] [PDF]  

Lars Erdtmann, Nathalie Franck, Hervé Lerat, Jacques Le Seyec, David Gilot, Isabelle Cannie, Philippe Gripon, Urszula Hibner, and Christiane Guguen-Guillouzo

The Hepatitis C Virus NS2 Protein Is an Inhibitor of CIDE-B-induced Apoptosis
J. Biol. Chem. 2003 278: 18256-18264. First Published on February 20, 2003; doi:10.1074/jbc.M209732200 [Abstract] [Full Text] [PDF]  

Gerard T. Berry, Shuang Wu, Roberto Buccafusca, Jun Ren, Linda W. Gonzales, Philip L. Ballard, Jeffrey A. Golden, Martin J. Stevens, and John J. Greer

Loss of Murine Na⁺/myo-Inositol Cotransporter Leads to Brain myo-Inositol Depletion and Central Apnea
J. Biol. Chem. 2003 278: 18297-18302. First Published on February 11, 2003; doi:10.1074/jbc.M213176200 [Abstract] [Full Text] [PDF]  

Gowrishankar Banumathy, Varsha Singh, Soundara Raghavan Pavithra, and Utpal Tatu

Heat Shock Protein 90 Function Is Essential for Plasmodium falciparum Growth in Human Erythrocytes
J. Biol. Chem. 2003 278: 18336-18345. First Published on February 12, 2003; doi:10.1074/jbc.M211309200 [Abstract] [Full Text] [PDF]  

Bu-er Wang, Jianyong Shou, Sarajane Ross, Hartmut Koeppen, Frederic J. de Sauvage, and Wei-Qiang Gao

Inhibition of Epithelial Ductal Branching in the Prostate by Sonic Hedgehog Is Indirectly Mediated by Stromal Cells
J. Biol. Chem. 2003 278: 18506-18513. First Published on March 7, 2003; doi:10.1074/jbc.M300968200 [Abstract] [Full Text] [PDF]  

Erbin Dai, Haiyan Guan, Liying Liu, Stephen Little, Grant McFadden, Sepideh Vaziri, Henian Cao, Iordanka A. Ivanova, Leila Bocksch, and Alexandra Lucas

Serp-1, a Viral Anti-inflammatory Serpin, Regulates Cellular Serine Proteinase and Serpin Responses to Vascular Injury
J. Biol. Chem. 2003 278: 18563-18572. First Published on March 10, 2003; doi:10.1074/jbc.M209683200 [Abstract] [Full Text] [PDF]  

Yasuko Takahashi, Ikuo Hayashi, Yusuke Tominari, Kentaro Rikimaru, Yuichi Morohashi, Toshiyuki Kan, Hideaki Natsugari, Tohru Fukuyama, Taisuke Tomita, and Takeshi Iwatsubo

Sulindac Sulfide Is a Noncompetitive -Secretase Inhibitor That Preferentially Reduces A42 Generation
J. Biol. Chem. 2003 278: 18664-18670. First Published on March 10, 2003; doi:10.1074/jbc.M301619200 [Abstract] [Full Text] [PDF]  

Additions and Corrections:

Simon Alberti, Jens Demand, Claudia Esser, Niels Emmerich, Hansjörg Schild, and Jörg Höhfeld

Ubiquitylation of BAG-1 suggests a novel regulatory mechanism during the sorting of chaperone substrates to the proteasome.
J. Biol. Chem. 2003 278: 18702-18703. [Full Text] [PDF]  

Jean-François Mercier, Ali Salahpour, Stéphane Angers, Andreas Breit, and Michel Bouvier

Quantitative assessment of ₁- and ₂-adrenergic re- receptor homo- and heterodimerization by bioluminescence resonance energy transfer.
J. Biol. Chem. 2003 278: 18704. [Full Text] [PDF]  

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