Minireviews:

Raymond E. Soccio and Jan L. Breslow

StAR-related Lipid Transfer (START) Proteins: Mediators of Intracellular Lipid Metabolism
J. Biol. Chem. 2003 278: 22183-22186. First Published on April 30, 2003; doi:10.1074/jbc.R300003200 [Full Text] [PDF]  

DNA: Replication Repair and Recombination:

Michele Giannattasio, Simone Sabbioneda, Mario Minuzzo, Paolo Plevani, and Marco Muzi-Falconi

Correlation between Checkpoint Activation and in Vivo Assembly of the Yeast Checkpoint Complex Rad17-Mec3-Ddc1
J. Biol. Chem. 2003 278: 22303-22308. First Published on April 2, 2003; doi:10.1074/jbc.M301260200 [Abstract] [Full Text] [PDF]  

Woei-horng Fang, Bo-Jeng Wang, Chiang-Hui Wang, Su-Jan Lee, Yu-Ting Chang, Yi-Kuang Chuang, and Chun-Nan Lee

DNA Loop Repair by Escherichia coli Cell Extracts
J. Biol. Chem. 2003 278: 22446-22452. First Published on April 11, 2003; doi:10.1074/jbc.M302585200 [Abstract] [Full Text] [PDF]  

Boris Kysela, Aidan J. Doherty, Miroslav Chovanec, Thomas Stiff, Simon M. Ameer-Beg, Borivoj Vojnovic, Pierre-Marie Girard, and Penny A. Jeggo

Ku Stimulation of DNA Ligase IV-dependent Ligation Requires Inward Movement along the DNA Molecule
J. Biol. Chem. 2003 278: 22466-22474. First Published on April 7, 2003; doi:10.1074/jbc.M303273200 [Abstract] [Full Text] [PDF]  

Tao Weitao, Martin Budd, Laura L. Mays Hoopes, and Judith L. Campbell

Dna2 Helicase/Nuclease Causes Replicative Fork Stalling and Double-strand Breaks in the Ribosomal DNA of Saccharomyces cerevisiae
J. Biol. Chem. 2003 278: 22513-22522. First Published on April 9, 2003; doi:10.1074/jbc.M301610200 [Abstract] [Full Text] [PDF]  

Belgin Cenkci, Jason L. Petersen, and Gary D. Small

REX1, a Novel Gene Required for DNA Repair
J. Biol. Chem. 2003 278: 22574-22577. First Published on April 14, 2003; doi:10.1074/jbc.M303249200 [Abstract] [Full Text] [PDF]  

Jeanine A. Harrigan, Patricia L. Opresko, Cayetano von Kobbe, Padmini S. Kedar, Rajendra Prasad, Samuel H. Wilson, and Vilhelm A. Bohr

The Werner Syndrome Protein Stimulates DNA Polymerase Strand Displacement Synthesis via Its Helicase Activity
J. Biol. Chem. 2003 278: 22686-22695. First Published on March 27, 2003; doi:10.1074/jbc.M213103200 [Abstract] [Full Text] [PDF]  

Linda Lee, Linda C. H. Chu, and Paul D. Sadowski

Cre Induces an Asymmetric DNA Bend in Its Target loxP Site
J. Biol. Chem. 2003 278: 23118-23129. First Published on April 9, 2003; doi:10.1074/jbc.M302272200 [Abstract] [Full Text] [PDF] Supplemental Data  

Genes: Structure and Regulation:

Monika Glinkowska, Jerzy Majka, Walter Messer, and Grzegorz Wegrzyn

The Mechanism of Regulation of Bacteriophage p_R Promoter Activity by Escherichia coli DnaA Protein
J. Biol. Chem. 2003 278: 22250-22256. First Published on March 24, 2003; doi:10.1074/jbc.M212492200 [Abstract] [Full Text] [PDF]  

Delphine Germain-Desprez, Martine Bazinet, Michel Bouvier, and Muriel Aubry

Oligomerization of Transcriptional Intermediary Factor 1 Regulators and Interaction with ZNF74 Nuclear Matrix Protein Revealed by Bioluminescence Resonance Energy Transfer in Living Cells
J. Biol. Chem. 2003 278: 22367-22373. First Published on April 8, 2003; doi:10.1074/jbc.M302234200 [Abstract] [Full Text] [PDF]  

Mrudula Ganga, Herbert M. Espinoza, Carol J. Cox, Lisa Morton, Tord A. Hjalt, Youngsook Lee, and Brad A. Amendt

PITX2 Isoform-specific Regulation of Atrial Natriuretic Factor Expression: SYNERGISM AND REPRESSION WITH Nkx2.5
J. Biol. Chem. 2003 278: 22437-22445. First Published on April 11, 2003; doi:10.1074/jbc.M210163200 [Abstract] [Full Text] [PDF]  

Rachel Hertz, Nadav Ben-Haim, Anca D. Petrescu, Bella Kalderon, Inna Berman, Naama Eldad, Friedhelm Schroeder, and Jacob Bar-Tana

Rescue of MODY-1 by Agonist Ligands of Hepatocyte Nuclear Factor-4
J. Biol. Chem. 2003 278: 22578-22585. First Published on April 15, 2003; doi:10.1074/jbc.M212138200 [Abstract] [Full Text] [PDF]  

Joachim Woelfle, Julia Billiard, and Peter Rotwein

Acute Control of Insulin-like Growth Factor-I Gene Transcription by Growth Hormone through Stat5b
J. Biol. Chem. 2003 278: 22696-22702. First Published on April 7, 2003; doi:10.1074/jbc.M301362200 [Abstract] [Full Text] [PDF]  

Wuyi Kong, Michael T. Longaker, and H. Peter Lorenz

Molecular Cloning and Expression of Keratinocyte Proline-rich Protein, a Novel Squamous Epithelial Marker Isolated During Skin Development
J. Biol. Chem. 2003 278: 22781-22786. First Published on March 31, 2003; doi:10.1074/jbc.M210488200 [Abstract] [Full Text] [PDF]  

Il Lae Jung and In Gyu Kim

Polyamines and Glutamate Decarboxylase-based Acid Resistance in Escherichia coli
J. Biol. Chem. 2003 278: 22846-22852. First Published on April 1, 2003; doi:10.1074/jbc.M212055200 [Abstract] [Full Text] [PDF]  

Nobuko Ohshima, Masahide Takahashi, and Fumiko Hirose

Identification of a Human Homologue of the DREF Transcription Factor with a Potential Role in Regulation of the Histone H1 Gene
J. Biol. Chem. 2003 278: 22928-22938. First Published on March 27, 2003; doi:10.1074/jbc.M303109200 [Abstract] [Full Text] [PDF]  

András Schaffer, Edmund C. Kim, Xiaoping Wu, Hong Zan, Lucia Testoni, Szilvia Salamon, Andrea Cerutti, and Paolo Casali

Selective Inhibition of Class Switching to IgG and IgE by Recruitment of the HoxC4 and Oct-1 Homeodomain Proteins and Ku70/Ku86 to Newly Identified ATTT cis-Elements
J. Biol. Chem. 2003 278: 23141-23150. First Published on April 2, 2003; doi:10.1074/jbc.M212952200 [Abstract] [Full Text] [PDF] Supplemental DataData Supplement  

RNA: Structure Metabolism and Catalysis:

Torsten H. Geerlings, Alex W. Faber, Milena D. Bister, Jan C. Vos, and Hendrik A. Raué

Rio2p, an Evolutionarily Conserved, Low Abundant Protein Kinase Essential for Processing of 20 S Pre-rRNA in Saccharomyces cerevisiae
J. Biol. Chem. 2003 278: 22537-22545. First Published on April 10, 2003; doi:10.1074/jbc.M300759200 [Abstract] [Full Text] [PDF]  

Bianca J. Lam, Arati Bakshi, Fatma Y. Ekinci, Jenny Webb, Brenton R. Graveley, and Klemens J. Hertel

Enhancer-dependent 5'-Splice Site Control of fruitless Pre-mRNA Splicing
J. Biol. Chem. 2003 278: 22740-22747. First Published on March 19, 2003; doi:10.1074/jbc.M301036200 [Abstract] [Full Text] [PDF]  

Protein Synthesis Post-Translation Modification and Degradation:

Valérie Chesneau, J. David Becherer, Yufang Zheng, Hediye Erdjument-Bromage, Paul Tempst, and Carl P. Blobel

Catalytic Properties of ADAM19
J. Biol. Chem. 2003 278: 22331-22340. First Published on April 7, 2003; doi:10.1074/jbc.M302781200 [Abstract] [Full Text] [PDF]  

Maria P. Rubtsova, Daria V. Sizova, Sergei E. Dmitriev, Dmitri S. Ivanov, Vladimir S. Prassolov, and Ivan N. Shatsky

Distinctive Properties of the 5'-Untranslated Region of Human Hsp70 mRNA
J. Biol. Chem. 2003 278: 22350-22356. First Published on April 7, 2003; doi:10.1074/jbc.M303213200 [Abstract] [Full Text] [PDF]  

Diana M. Fries, Evgenia Paxinou, Marios Themistocleous, Eric Swanberg, Kathy K. Griendling, Daniela Salvemini, Jan W. Slot, Harry F. G. Heijnen, Stanley L. Hazen, and Harry Ischiropoulos

Expression of Inducible Nitric-oxide Synthase and Intracellular Protein Tyrosine Nitration in Vascular Smooth Muscle Cells: ROLE OF REACTIVE OXYGEN SPECIES
J. Biol. Chem. 2003 278: 22901-22907. First Published on April 10, 2003; doi:10.1074/jbc.M210806200 [Abstract] [Full Text] [PDF]  

Paul C. Evans, Trevor S. Smith, Meng-Jiun Lai, Mark G. Williams, David F. Burke, Karen Heyninck**, Marja M. Kreike, Rudi Beyaert, Tom L. Blundell, and Peter J. Kilshaw

A Novel Type of Deubiquitinating Enzyme
J. Biol. Chem. 2003 278: 23180-23186. First Published on April 7, 2003; doi:10.1074/jbc.M301863200 [Abstract] [Full Text] [PDF] Supplemental Data  

Protein Structure and Folding:

Adrian C. Apetri and Witold K. Surewicz

Atypical Effect of Salts on the Thermodynamic Stability of Human Prion Protein
J. Biol. Chem. 2003 278: 22187-22192. First Published on April 3, 2003; doi:10.1074/jbc.M302130200 [Abstract] [Full Text] [PDF]  

Christian W. Kauth, Christian Epp, Hermann Bujard, and Rolf Lutz

The Merozoite Surface Protein 1 Complex of Human Malaria Parasite Plasmodium falciparum: INTERACTIONS AND ARRANGEMENTS OF SUBUNITS
J. Biol. Chem. 2003 278: 22257-22264. First Published on March 24, 2003; doi:10.1074/jbc.M302299200 [Abstract] [Full Text] [PDF]  

Heinte Lesso and Ronald A. Li

Helical Secondary Structure of the External S3-S4 Linker of Pacemaker (HCN) Channels Revealed by Site-dependent Perturbations of Activation Phenotype
J. Biol. Chem. 2003 278: 22290-22297. First Published on March 31, 2003; doi:10.1074/jbc.M302466200 [Abstract] [Full Text] [PDF]  

Marc-André Langlois, Youssef El Fakhry, and Walid Mourad

Zinc-binding Sites in the N Terminus of Mycoplasma arthritidis-derived Mitogen Permit the Dimer Formation Required for High Affinity Binding to HLA-DR and for T Cell Activation
J. Biol. Chem. 2003 278: 22309-22315. First Published on April 3, 2003; doi:10.1074/jbc.M300823200 [Abstract] [Full Text] [PDF]  

Karen M. Duda and Charles L. Brooks

Identification of Residues Outside the Two Binding Sites That Are Critical for Activation of the Lactogenic Activity of Human Growth Hormone
J. Biol. Chem. 2003 278: 22734-22739. First Published on April 7, 2003; doi:10.1074/jbc.M212550200 [Abstract] [Full Text] [PDF]  

Björn Kauppi, Clarissa Jakob, Mathias Färnegårdh, Jie Yang, Harri Ahola, Maria Alarcon, Karin Calles, Owe Engström, John Harlan, Steven Muchmore, Anna-Karin Ramqvist, Susanne Thorell, Lars Öhman, Jonathan Greer, Jan-Åke Gustafsson, Jan Carlstedt-Duke, and Mats Carlquist

The Three-dimensional Structures of Antagonistic and Agonistic Forms of the Glucocorticoid Receptor Ligand-binding Domain: RU-486 INDUCES A TRANSCONFORMATION THAT LEADS TO ACTIVE ANTAGONISM
J. Biol. Chem. 2003 278: 22748-22754. First Published on April 9, 2003; doi:10.1074/jbc.M212711200 [Abstract] [Full Text] [PDF]  

Craig A. Plambeck, Ann H. Y. Kwan, David J. Adams, Belinda J. Westman, Louise van der Weyden, Robert L. Medcalf, Brian J. Morris, and Joel P. Mackay

The Structure of the Zinc Finger Domain from Human Splicing Factor ZNF265 Fold
J. Biol. Chem. 2003 278: 22805-22811. First Published on March 25, 2003; doi:10.1074/jbc.M301896200 [Abstract] [Full Text] [PDF]  

Hikaru Hemmi, Jun Ishibashi, Tetsuya Tomie, and Minoru Yamakawa

Structural Basis for New Pattern of Conserved Amino Acid Residues Related to Chitin-binding in the Antifungal Peptide from the Coconut Rhinoceros Beetle Oryctes rhinoceros
J. Biol. Chem. 2003 278: 22820-22827. First Published on April 3, 2003; doi:10.1074/jbc.M301025200 [Abstract] [Full Text] [PDF]  

Thierry Rose, Jean-Louis Moreau, Ralph Eckenberg, and Jacques Thèze

Structural Analysis and Modeling of a Synthetic Interleukin-2 Mimetic and Its Interleukin-2R₂ Receptor
J. Biol. Chem. 2003 278: 22868-22876. First Published on April 3, 2003; doi:10.1074/jbc.M301757200 [Abstract] [Full Text] [PDF]  

Darin L. Lee, Colin T. Mant, and Robert S. Hodges

A Novel Method to Measure Self-association of Small Amphipathic Molecules: TEMPERATURE PROFILING IN REVERSED-PHASE CHROMATOGRAPHY
J. Biol. Chem. 2003 278: 22918-22927. First Published on April 9, 2003; doi:10.1074/jbc.M301777200 [Abstract] [Full Text] [PDF]  

Masaru Goto, Rie Omi, Ikuko Miyahara, Mitsuaki Sugahara, and Ken Hirotsu

Structures of Argininosuccinate Synthetase in Enzyme-ATP Substrates and Enzyme-AMP Product Forms: STEREOCHEMISTRY OF THE CATALYTIC REACTION
J. Biol. Chem. 2003 278: 22964-22971. First Published on April 8, 2003; doi:10.1074/jbc.M213198200 [Abstract] [Full Text] [PDF]  

Oliver H. Weiergräber, Ivan I. Senin, Pavel P. Philippov, Joachim Granzin, and Karl-Wilhelm Koch

Impact of N-terminal Myristoylation on the Ca²⁺-dependent Conformational Transition in Recoverin
J. Biol. Chem. 2003 278: 22972-22979. First Published on April 9, 2003; doi:10.1074/jbc.M300447200 [Abstract] [Full Text] [PDF]  

Francisco G. Hernandez-Guzman, Tadayoshi Higashiyama, Walter Pangborn, Yoshio Osawa, and Debashis Ghosh

Structure of Human Estrone Sulfatase Suggests Functional Roles of Membrane Association
J. Biol. Chem. 2003 278: 22989-22997. First Published on March 25, 2003; doi:10.1074/jbc.M211497200 [Abstract] [Full Text] [PDF]  

Fan Gao, Nina Bern, Alicia Little, Hai-Long Wang, Scott B. Hansen, Todd T. Talley, Palmer Taylor, and Steven M. Sine

Curariform Antagonists Bind in Different Orientations to Acetylcholine-binding Protein
J. Biol. Chem. 2003 278: 23020-23026. First Published on April 7, 2003; doi:10.1074/jbc.M301151200 [Abstract] [Full Text] [PDF]  

Thomas R. M. Barends, Jolanda J. Polderman-Tijmes, Peter A. Jekel, Charles M. H. Hensgens, Erik J. de Vries, Dick B. Janssen, and Bauke W. Dijkstra

The Sequence and Crystal Structure of the -Amino Acid Ester Hydrolase from Xanthomonas citri Define a New Family of -Lactam Antibiotic Acylases
J. Biol. Chem. 2003 278: 23076-23084. First Published on April 8, 2003; doi:10.1074/jbc.M302246200 [Abstract] [Full Text] [PDF]  

Shiva Malek, De-Bin Huang, Tom Huxford, Sankar Ghosh, and Gourisankar Ghosh

X-ray Crystal Structure of an IB·NF-B p65 Homodimer Complex
J. Biol. Chem. 2003 278: 23094-23100. First Published on April 9, 2003; doi:10.1074/jbc.M301022200 [Abstract] [Full Text] [PDF]  

Martina Ralle, Svetlana Lutsenko, and Ninian J. Blackburn

X-ray Absorption Spectroscopy of the Copper Chaperone HAH1 Reveals a Linear Two-coordinate Cu(I) Center Capable of Adduct Formation with Exogenous Thiols and Phosphines
J. Biol. Chem. 2003 278: 23163-23170. First Published on April 9, 2003; doi:10.1074/jbc.M303474200 [Abstract] [Full Text] [PDF]  

Isam Qahwash, Katherine L. Weiland, Yifeng Lu, Ronald W. Sarver, Rolf F. Kletzien, and Riqiang Yan

Identification of a Mutant Amyloid Peptide That Predominantly Forms Neurotoxic Protofibrillar Aggregates
J. Biol. Chem. 2003 278: 23187-23195. First Published on April 8, 2003; doi:10.1074/jbc.M213298200 [Abstract] [Full Text] [PDF]  

Enzyme Catalysis and Regulation:

Staffan Thorén, Rolf Weinander, Sipra Saha, Caroline Jegerschöld, Pär L. Pettersson, Bengt Samuelsson, Hans Hebert, Mats Hamberg, Ralf Morgenstern, and Per-Johan Jakobsson

Human Microsomal Prostaglandin E Synthase-1: PURIFICATION, FUNCTIONAL CHARACTERIZATION, AND PROJECTION STRUCTURE DETERMINATION
J. Biol. Chem. 2003 278: 22199-22209. First Published on April 2, 2003; doi:10.1074/jbc.M303227200 [Abstract] [Full Text] [PDF]  

Bruce A. Palfey, Yerramilli V. S. N. Murthy, and Vincent Massey

Altered Balance of Half-reactions in p-Hydroxybenzoate Hydroxylase Caused by Substituting the 2'-Carbon of FAD with Fluorine
J. Biol. Chem. 2003 278: 22210-22216. First Published on April 8, 2003; doi:10.1074/jbc.M301830200 [Abstract] [Full Text] [PDF]  

Fumiaki Suzuki, Makoto Hayakawa, Tsutomu Nakagawa, Uddin Mohammad Nasir, Akio Ebihara, Atsushi Iwasawa, Yuichi Ishida, Yukio Nakamura, and Kazuo Murakami

Human Prorenin Has "Gate and Handle" Regions for Its Non-proteolytic Activation
J. Biol. Chem. 2003 278: 22217-22222. First Published on April 8, 2003; doi:10.1074/jbc.M302579200 [Abstract] [Full Text] [PDF]  

Robert Elsby, Neil R. Kitteringham, Christopher E. Goldring, Cerys A. Lovatt, Mark Chamberlain, Colin J. Henderson, C. Roland Wolf, and B. Kevin Park

Increased Constitutive c-Jun N-terminal Kinase Signaling in Mice Lacking Glutathione S-Transferase Pi
J. Biol. Chem. 2003 278: 22243-22249. First Published on March 19, 2003; doi:10.1074/jbc.M301211200 [Abstract] [Full Text] [PDF]  

Alessandra Bonamore, Patrizia Gentili, Andrea Ilari, M. Eugenia Schininà, and Alberto Boffi

Escherichia coli Flavohemoglobin Is an Efficient Alkylhydroperoxide Reductase
J. Biol. Chem. 2003 278: 22272-22277. First Published on March 27, 2003; doi:10.1074/jbc.M301285200 [Abstract] [Full Text] [PDF]  

Christopher Horst Lillig, Aristi Potamitou, Jens-Dirk Schwenn, Alexios Vlamis-Gardikas, and Arne Holmgren

Redox Regulation of 3'-Phosphoadenylylsulfate Reductase from Escherichia coli by Glutathione and Glutaredoxins
J. Biol. Chem. 2003 278: 22325-22330. First Published on April 7, 2003; doi:10.1074/jbc.M302304200 [Abstract] [Full Text] [PDF]  

Amanda A. Brindley, Evelyne Raux, Helen K. Leech, Heidi L. Schubert, and Martin J. Warren

A Story of Chelatase Evolution: IDENTIFICATION AND CHARACTERIZATION OF A SMALL 13–15-kDa "ANCESTRAL" COBALTOCHELATASE (CbiX^S) IN THE ARCHAEA
J. Biol. Chem. 2003 278: 22388-22395. First Published on April 9, 2003; doi:10.1074/jbc.M302468200 [Abstract] [Full Text] [PDF]  

Pia Nyberg, Pia Heikkilä, Timo Sorsa, Jani Luostarinen, Ritva Heljasvaara, Ulf-Håkan Stenman, Taina Pihlajaniemi, and Tuula Salo

Endostatin Inhibits Human Tongue Carcinoma Cell Invasion and Intravasation and Blocks the Activation of Matrix Metalloprotease-2, -9, and -13
J. Biol. Chem. 2003 278: 22404-22411. First Published on April 10, 2003; doi:10.1074/jbc.M210325200 [Abstract] [Full Text] [PDF]  

Lan Zhu, Constantin Tamvakopoulos, Dan Xie, Jasminka Dragovic, Xiaolan Shen, Judith E. Fenyk-Melody, Keith Schmidt, Ansuman Bagchi, Patrick R. Griffin, Nancy A. Thornberry, and Ranabir Sinha Roy

The Role of Dipeptidyl Peptidase IV in the Cleavage of Glucagon Family Peptides: IN VIVO METABOLISM OF PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE-(1–38)
J. Biol. Chem. 2003 278: 22418-22423. First Published on April 10, 2003; doi:10.1074/jbc.M212355200 [Abstract] [Full Text] [PDF]  

Diane E. Heck, Anna M. Vetrano, Thomas M. Mariano, and Jeffrey D. Laskin

UVB Light Stimulates Production of Reactive Oxygen Species: UNEXPECTED ROLE FOR CATALASE
J. Biol. Chem. 2003 278: 22432-22436. First Published on May 1, 2003; doi:10.1074/jbc.C300048200 [Abstract] [Full Text] [PDF]  

Ming-Tain Lai, Elizabeth Chen, Ming-Chih Crouthamel, Jillian DiMuzio-Mower, Min Xu, Qian Huang, Eric Price, R. Bruce Register, Xiao-Ping Shi, Dorit B. Donoviel, Alan Bernstein, Daria Hazuda, Stephen J. Gardell, and Yue-Ming Li

Presenilin-1 and Presenilin-2 Exhibit Distinct yet Overlapping -Secretase Activities
J. Biol. Chem. 2003 278: 22475-22481. First Published on April 8, 2003; doi:10.1074/jbc.M300974200 [Abstract] [Full Text] [PDF]  

Emma J. Collinson and Chris M. Grant

Role of Yeast Glutaredoxins as Glutathione S-transferases
J. Biol. Chem. 2003 278: 22492-22497. First Published on April 8, 2003; doi:10.1074/jbc.M301387200 [Abstract] [Full Text] [PDF]  

Nermin Kuzkaya, Norbert Weissmann, David G. Harrison, and Sergey Dikalov

Interactions of Peroxynitrite, Tetrahydrobiopterin, Ascorbic Acid, and Thiols: IMPLICATIONS FOR UNCOUPLING ENDOTHELIAL NITRIC-OXIDE SYNTHASE
J. Biol. Chem. 2003 278: 22546-22554. First Published on April 10, 2003; doi:10.1074/jbc.M302227200 [Abstract] [Full Text] [PDF]  

Coy D. Fitch, Yi-feng Chen, and Guang-zuan Cai

Chloroquine-induced Masking of a Lipid That Promotes Ferriprotoporphyrin IX Dimerization in Malaria
J. Biol. Chem. 2003 278: 22596-22599. First Published on April 15, 2003; doi:10.1074/jbc.M301407200 [Abstract] [Full Text] [PDF]  

Mitali Sarkar, Christopher J. Hamilton, and Alan H. Fairlamb

Properties of Phosphoenolpyruvate Mutase, the First Enzyme in the Aminoethylphosphonate Biosynthetic Pathway in Trypanosoma cruzi
J. Biol. Chem. 2003 278: 22703-22708. First Published on April 2, 2003; doi:10.1074/jbc.M302419200 [Abstract] [Full Text] [PDF]  

Naoki Shibata, Yuka Nakanishi, Masaki Fukuoka, Mamoru Yamanishi, Noritake Yasuoka, and Tetsuo Toraya

Structural Rationalization for the Lack of Stereospecificity in Coenzyme B₁₂-dependent Diol Dehydratase
J. Biol. Chem. 2003 278: 22717-22725. First Published on April 8, 2003; doi:10.1074/jbc.M301513200 [Abstract] [Full Text] [PDF]  

Subray S. Hegde and John S. Blanchard

Kinetic and Mechanistic Characterization of Recombinant Lactobacillus viridescens FemX (UDP-N-acetylmuramoyl Pentapeptide-lysine N⁶-Alanyltransferase)
J. Biol. Chem. 2003 278: 22861-22867. First Published on April 4, 2003; doi:10.1074/jbc.M301565200 [Abstract] [Full Text] [PDF]  

Steven N. Reuland, Alexander P. Vlasov, and Sergey A. Krupenko

Disruption of a Calmodulin Central Helix-like Region of 10-Formyltetrahydrofolate Dehydrogenase Impairs Its Dehydrogenase Activity by Uncoupling the Functional Domains
J. Biol. Chem. 2003 278: 22894-22900. First Published on April 8, 2003; doi:10.1074/jbc.M302948200 [Abstract] [Full Text] [PDF]  

Metabolism and Bioenergetics:

Michael J. Considine, Megan Goodman, Karim S. Echtay, Maryse Laloi, James Whelan, Martin D. Brand, and Lee J. Sweetlove

Superoxide Stimulates a Proton Leak in Potato Mitochondria That Is Related to the Activity of Uncoupling Protein
J. Biol. Chem. 2003 278: 22298-22302. First Published on April 2, 2003; doi:10.1074/jbc.M301075200 [Abstract] [Full Text] [PDF]  

Glycobiology and Extracellular Matrices:

Isabelle Pelletier, Tomomi Hashidate, Tadasu Urashima, Nozomu Nishi, Takanori Nakamura, Masamitsu Futai, Yoichiro Arata, Ken-ichi Kasai, Mitsuomi Hirashima, Jun Hirabayashi, and Sachiko Sato

Specific Recognition of Leishmania major Poly--galactosyl Epitopes by Galectin-9: POSSIBLE IMPLICATION OF GALECTIN-9 IN INTERACTION BETWEEN L. MAJOR AND HOST CELLS
J. Biol. Chem. 2003 278: 22223-22230. First Published on April 8, 2003; doi:10.1074/jbc.M302693200 [Abstract] [Full Text] [PDF]  

Cecilia D'Alessio, Eduardo S. Trombetta, and Armando J. Parodi

Nucleoside Diphosphatase and Glycosyltransferase Activities Can Localize to Different Subcellular Compartments in Schizosaccharomyces pombe
J. Biol. Chem. 2003 278: 22379-22387. First Published on April 9, 2003; doi:10.1074/jbc.M300892200 [Abstract] [Full Text] [PDF]  

Christian Thiel, Markus Schwarz, Jianhe Peng, Michal Grzmil, Martin Hasilik, Thomas Braulke, Alfried Kohlschütter, Kurt von Figura, Ludwig Lehle, and Christian Körner

A New Type of Congenital Disorders of Glycosylation (CDG-Ii) Provides New Insights into the Early Steps of Dolichol-linked Oligosaccharide Biosynthesis
J. Biol. Chem. 2003 278: 22498-22505. First Published on April 8, 2003; doi:10.1074/jbc.M302850200 [Abstract] [Full Text] [PDF]  

Akiko Tsuchida, Tetsuya Okajima, Keiko Furukawa, Takayuki Ando, Hideharu Ishida, Aruto Yoshida, Yoko Nakamura, Reiji Kannagi, Makoto Kiso, and Koichi Furukawa

Synthesis of Disialyl Lewis a (Le^a) Structure in Colon Cancer Cell Lines by a Sialyltransferase, ST6GalNAc VI, Responsible for the Synthesis of -Series Gangliosides
J. Biol. Chem. 2003 278: 22787-22794. First Published on March 31, 2003; doi:10.1074/jbc.M211034200 [Abstract] [Full Text] [PDF]  

Kazuhisa Aoki, Nobuhiro Ishida, and Masao Kawakita

Substrate Recognition by Nucleotide Sugar Transporters: FURTHER CHARACTERIZATION OF SUBSTRATE RECOGNITION REGIONS BY ANALYSES OF UDP-GALACTOSE/CMP-SIALIC ACID TRANSPORTER CHIMERAS AND BIOCHEMICAL ANALYSIS OF THE SUBSTRATE SPECIFICITY OF PARENTAL AND CHIMERIC TRANSPORTERS
J. Biol. Chem. 2003 278: 22887-22893. First Published on April 7, 2003; doi:10.1074/jbc.M302620200 [Abstract] [Full Text] [PDF]  

Arne Engelsberg, Ricardo Hermosilla, Uwe Karsten, Ralf Schülein, Bernd Dörken, and Armin Rehm

The Golgi Protein RCAS1 Controls Cell Surface Expression of Tumor-associated O-Linked Glycan Antigens
J. Biol. Chem. 2003 278: 22998-23007. First Published on April 2, 2003; doi:10.1074/jbc.M301361200 [Abstract] [Full Text] [PDF]  

Lipids and Lipoproteins:

Kerry-Anne Rye, Kevin Wee, Linda K. Curtiss, David J. Bonnet, and Philip J. Barter

Apolipoprotein A-II Inhibits High Density Lipoprotein Remodeling and Lipid-poor Apolipoprotein A-I Formation
J. Biol. Chem. 2003 278: 22530-22536. First Published on April 10, 2003; doi:10.1074/jbc.M213250200 [Abstract] [Full Text] [PDF]  

Tatyana G. Vishnyakova, Alexander V. Bocharov, Irina N. Baranova, Zhigang Chen, Alan T. Remaley, Gyorgy Csako, Thomas L. Eggerman, and Amy P. Patterson

Binding and Internalization of Lipopolysaccharide by Cla-1, a Human Orthologue of Rodent Scavenger Receptor B1
J. Biol. Chem. 2003 278: 22771-22780. First Published on March 21, 2003; doi:10.1074/jbc.M211032200 [Abstract] [Full Text] [PDF]  

Erik G. Lund, Chonglun Xie, Tiina Kotti, Stephen D. Turley, John M. Dietschy, and David W. Russell

Knockout of the Cholesterol 24-Hydroxylase Gene in Mice Reveals a Brain-specific Mechanism of Cholesterol Turnover
J. Biol. Chem. 2003 278: 22980-22988. First Published on April 9, 2003; doi:10.1074/jbc.M303415200 [Abstract] [Full Text] [PDF]  

Trina L. McIlhargey, Yingying Yang, Howard Wong, and John S. Hill

Identification of a Lipoprotein Lipase Cofactor-binding Site by Chemical Cross-linking and Transfer of Apolipoprotein C-II-responsive Lipolysis from Lipoprotein Lipase to Hepatic Lipase
J. Biol. Chem. 2003 278: 23027-23035. First Published on April 7, 2003; doi:10.1074/jbc.M300315200 [Abstract] [Full Text] [PDF]  

Membrane Transport Structure Function and Biogenesis:

Eugenia Mileykovskaya, Itzhak Fishov, Xueyao Fu, Brian D. Corbin, William Margolin, and William Dowhan

Effects of Phospholipid Composition on MinD-Membrane Interactions in Vitro and in Vivo
J. Biol. Chem. 2003 278: 22193-22198. First Published on April 3, 2003; doi:10.1074/jbc.M302603200 [Abstract] [Full Text] [PDF]  

Claudia V. Filomatori and Alcides F. Rega

On the Mechanism of Activation of the Plasma Membrane Ca²⁺-ATPase by ATP and Acidic Phospholipids
J. Biol. Chem. 2003 278: 22265-22271. First Published on March 26, 2003; doi:10.1074/jbc.M302657200 [Abstract] [Full Text] [PDF]  

Kees Venema, Andrés Belver, M. Carmen Marín-Manzano, M. Pilar Rodríguez-Rosales, and Juan Pedro Donaire

A Novel Intracellular K⁺/H⁺ Antiporter Related to Na⁺/H⁺ Antiporters Is Important for K⁺ Ion Homeostasis in Plants
J. Biol. Chem. 2003 278: 22453-22459. First Published on April 14, 2003; doi:10.1074/jbc.M210794200 [Abstract] [Full Text] [PDF]  

Guillermo Avila, Eun Hui Lee, Claudio F. Perez, P. D. Allen, and Robert T. Dirksen

FKBP12 Binding to RyR1 Modulates Excitation-Contraction Coupling in Mouse Skeletal Myotubes
J. Biol. Chem. 2003 278: 22600-22608. First Published on April 17, 2003; doi:10.1074/jbc.M205866200 [Abstract] [Full Text] [PDF]  

Kenji Kuwasako, Kazuo Kitamura, Yasuko Nagoshi, Yuan-Ning Cao, and Tanenao Eto

Identification of the Human Receptor Activity-modifying Protein 1 Domains Responsible for Agonist Binding Specificity
J. Biol. Chem. 2003 278: 22623-22630. First Published on April 8, 2003; doi:10.1074/jbc.M302571200 [Abstract] [Full Text] [PDF]  

Michiko Suzuki, Hiroshi Suzuki, Yoshikazu Sugimoto, and Yuichi Sugiyama

ABCG2 Transports Sulfated Conjugates of Steroids and Xenobiotics
J. Biol. Chem. 2003 278: 22644-22649. First Published on April 7, 2003; doi:10.1074/jbc.M212399200 [Abstract] [Full Text] [PDF]  

Makoto Suzuki, Atsuko Mizuno, Kunihiko Kodaira, and Masashi Imai

Impaired Pressure Sensation in Mice Lacking TRPV4
J. Biol. Chem. 2003 278: 22664-22668. First Published on April 13, 2003; doi:10.1074/jbc.M302561200 [Abstract] [Full Text] [PDF]  

Petra Malovrh, Gabriella Viero, Mauro Dalla Serra, Zdravko Podlesek, Jeremy H. Lakey, Peter Macek, Gianfranco Menestrina, and Gregor Anderluh

A Novel Mechanism of Pore Formation: MEMBRANE PENETRATION BY THE N-TERMINAL AMPHIPATHIC REGION OF EQUINATOXIN
J. Biol. Chem. 2003 278: 22678-22685. First Published on April 2, 2003; doi:10.1074/jbc.M300622200 [Abstract] [Full Text] [PDF]  

Akiko Yamaji-Hasegawa, Asami Makino, Takeshi Baba, Yukiko Senoh, Hiromi Kimura-Suda, Satoshi B. Sato, Nobuo Terada, Shinichi Ohno, Etsuko Kiyokawa, Masato Umeda, and Toshihide Kobayashi

Oligomerization and Pore Formation of a Sphingomyelin-specific Toxin, Lysenin
J. Biol. Chem. 2003 278: 22762-22770. First Published on April 3, 2003; doi:10.1074/jbc.M213209200 [Abstract] [Full Text] [PDF]  

Toshikazu Konno, Takuya Ebihara, Keiji Hisaeda, Takeshi Uchiumi, Takanori Nakamura, Takayuki Shirakusa, Michihiko Kuwano, and Morimasa Wada

Identification of Domains Participating in the Substrate Specificity and Subcellular Localization of the Multidrug Resistance Proteins MRP1 and MRP2
J. Biol. Chem. 2003 278: 22908-22917. First Published on April 7, 2003; doi:10.1074/jbc.M302868200 [Abstract] [Full Text] [PDF]  

Qi Zeng, Thi Ton Hoai Tran, Hui-Xian Tan, and Wanjin Hong

The Cytoplasmic Domain of Vamp4 and Vamp5 Is Responsible for Their Correct Subcellular Targeting: THE N-TERMINAL EXTENSION OF VAMP4 CONTAINS A DOMINANT AUTONOMOUS TARGETING SIGNAL FOR THE TRANS-GOLGI NETWORK
J. Biol. Chem. 2003 278: 23046-23054. First Published on April 6, 2003; doi:10.1074/jbc.M303214200 [Abstract] [Full Text] [PDF]  

Dana Yoo, Bo Young Kim, Cristina Campo, Latreece Nance, Amanda King, Djikolngar Maouyo, and Paul A. Welling

Cell Surface Expression of the ROMK (Kir 1.1) Channel Is Regulated by the Aldosterone-induced Kinase, SGK-1, and Protein Kinase A
J. Biol. Chem. 2003 278: 23066-23075. First Published on April 8, 2003; doi:10.1074/jbc.M212301200 [Abstract] [Full Text] [PDF]  

Ina L. Urbatsch, Grace A. Tyndall, Gregory Tombline, and Alan E. Senior

P-glycoprotein Catalytic Mechanism: STUDIES OF THE ADP-VANADATE INHIBITED STATE
J. Biol. Chem. 2003 278: 23171-23179. First Published on April 1, 2003; doi:10.1074/jbc.M301957200 [Abstract] [Full Text] [PDF]  

Mechanisms Of Signal Transduction:

David J. Mancuso, Dana R. Abendschein, Christopher M. Jenkins, Xianlin Han, Jeffrey E. Saffitz, Richard B. Schuessler, and Richard W. Gross

Cardiac Ischemia Activates Calcium-independent Phospholipase A₂, Precipitating Ventricular Tachyarrhythmias in Transgenic Mice: RESCUE OF THE LETHAL ELECTROPHYSIOLOGIC PHENOTYPE BY MECHANISM-BASED INHIBITION
J. Biol. Chem. 2003 278: 22231-22236. First Published on April 28, 2003; doi:10.1074/jbc.C300033200 [Abstract] [Full Text] [PDF]  

Xuecui Guo, Robert E. Gerl, and John W. Schrader

Defining the Involvement of p38 MAPK in the Production of Anti- and Proinflammatory Cytokines Using an SB 203580-resistant Form of the Kinase
J. Biol. Chem. 2003 278: 22237-22242. First Published on March 11, 2003; doi:10.1074/jbc.M300847200 [Abstract] [Full Text] [PDF]  

Zhu Chen, Malavika Raman, Linda Chen, Sheu Fen Lee, Alfred G. Gilman, and Melanie H. Cobb

TAO (Thousand-and-one Amino Acid) Protein Kinases Mediate Signaling from Carbachol to p38 Mitogen-activated Protein Kinase and Ternary Complex Factors
J. Biol. Chem. 2003 278: 22278-22283. First Published on March 28, 2003; doi:10.1074/jbc.M301173200 [Abstract] [Full Text] [PDF]  

Yuqi Wang, Qing Ge, Dayle Houston, Jeremy Thorner, Beverly Errede, and Henrik G. Dohlman

Regulation of Ste7 Ubiquitination by Ste11 Phosphorylation and the Skp1-Cullin-F-box Complex
J. Biol. Chem. 2003 278: 22284-22289. First Published on March 31, 2003; doi:10.1074/jbc.M301272200 [Abstract] [Full Text] [PDF]  

Raquel Del Toro, Konstantin L. Levitsky, José López-Barneo, and María D. Chiara

Induction of T-type Calcium Channel Gene Expression by Chronic Hypoxia
J. Biol. Chem. 2003 278: 22316-22324. First Published on April 4, 2003; doi:10.1074/jbc.M212576200 [Abstract] [Full Text] [PDF]  

Cagri Giray Besirli and Eugene Malcolm Johnson, Jr.

JNK-independent Activation of c-Jun during Neuronal Apoptosis Induced by Multiple DNA-damaging Agents
J. Biol. Chem. 2003 278: 22357-22366. First Published on April 8, 2003; doi:10.1074/jbc.M300742200 [Abstract] [Full Text] [PDF]  

Armelle A. Troussard, Nasrin M. Mawji, Christopher Ong, Alice Mui, René St.-Arnaud, and Shoukat Dedhar

Conditional Knock-out of Integrin-linked Kinase Demonstrates an Essential Role in Protein Kinase B/Akt Activation
J. Biol. Chem. 2003 278: 22374-22378. First Published on April 8, 2003; doi:10.1074/jbc.M303083200 [Abstract] [Full Text] [PDF]  

Nicholas J. Hutchings, Nicholas Clarkson, Robert Chalkley, A. Neil Barclay, and Marion H. Brown

Linking the T Cell Surface Protein CD2 to the Actin-capping Protein CAPZ via CMS and CIN85
J. Biol. Chem. 2003 278: 22396-22403. First Published on April 10, 2003; doi:10.1074/jbc.M302540200 [Abstract] [Full Text] [PDF]  

Kim M. T. de Bruyn, Fried J. T. Zwartkruis, Johan de Rooij, Jan-Willem N. Akkerman, and Johannes L. Bos

The Small GTPase Rap1 Is Activated by Turbulence and Is Involved in Integrin _IIb3-mediated Cell Adhesion in Human Megakaryocytes
J. Biol. Chem. 2003 278: 22412-22417. First Published on April 10, 2003; doi:10.1074/jbc.M212036200 [Abstract] [Full Text] [PDF]  

Subhajit Dasgupta, Malabendu Jana, Xiaojuan Liu, and Kalipada Pahan

Role of Very-late Antigen-4 (VLA-4) in Myelin Basic Protein-primed T Cell Contact-induced Expression of Proinflammatory Cytokines in Microglial Cells
J. Biol. Chem. 2003 278: 22424-22431. First Published on April 10, 2003; doi:10.1074/jbc.M301789200 [Abstract] [Full Text] [PDF]  

Yair Ben-Chaim, Oded Tour, Nathan Dascal, Itzchak Parnas, and Hanna Parnas

The M₂ Muscarinic G-protein-coupled Receptor Is Voltage-sensitive
J. Biol. Chem. 2003 278: 22482-22491. First Published on April 8, 2003; doi:10.1074/jbc.M301146200 [Abstract] [Full Text] [PDF]  

Sang Hoon Rhee, Bryan W. Jones, Vladimir Toshchakov, Stefanie N. Vogel, and Matthew J. Fenton

Toll-like Receptors 2 and 4 Activate STAT1 Serine Phosphorylation by Distinct Mechanisms in Macrophages
J. Biol. Chem. 2003 278: 22506-22512. First Published on April 9, 2003; doi:10.1074/jbc.M208633200 [Abstract] [Full Text] [PDF]  

Baochong Gao and Min-Fu Tsan

Recombinant Human Heat Shock Protein 60 Does Not Induce the Release of Tumor Necrosis Factor from Murine Macrophages
J. Biol. Chem. 2003 278: 22523-22529. First Published on April 9, 2003; doi:10.1074/jbc.M303161200 [Abstract] [Full Text] [PDF]  

Christine E. Pullar, Jin Chen, and R. Rivkah Isseroff

PP2A Activation by ₂-Adrenergic Receptor Agonists: NOVEL REGULATORY MECHANISM OF KERATINOCYTE MIGRATION
J. Biol. Chem. 2003 278: 22555-22562. First Published on April 14, 2003; doi:10.1074/jbc.M300205200 [Abstract] [Full Text] [PDF]  

Seon-Ju Yeo, Demetrius Gravis, Jae-Geun Yoon, and Ae-Kyung Yi

Myeloid Differentiation Factor 88-dependent Transcriptional Regulation of Cyclooxygenase-2 Expression by CpG DNA: ROLE OF NF-B AND p38
J. Biol. Chem. 2003 278: 22563-22573. First Published on April 14, 2003; doi:10.1074/jbc.M302076200 [Abstract] [Full Text] [PDF]  

Alpana Ray, Papiya Ray, Nicole Guthrie, Arvind Shakya, Deepak Kumar, and Bimal K. Ray

Protein Kinase A Signaling Pathway Regulates Transcriptional Activity of SAF-1 by Unmasking Its DNA-binding Domains
J. Biol. Chem. 2003 278: 22586-22595. First Published on April 15, 2003; doi:10.1074/jbc.M300705200 [Abstract] [Full Text] [PDF]  

Runxiang Zhao, Xueqi Fu, Qingshan Li, Sanford B. Krantz, and Zhizhuang Joe Zhao

Specific Interaction of Protein Tyrosine Phosphatase-MEG2 with Phosphatidylserine
J. Biol. Chem. 2003 278: 22609-22614. First Published on April 17, 2003; doi:10.1074/jbc.M301560200 [Abstract] [Full Text] [PDF]  

Isabel Hunger-Glaser, Eduardo Perez Salazar, James Sinnett-Smith, and Enrique Rozengurt

Bombesin, Lysophosphatidic Acid, and Epidermal Growth Factor Rapidly Stimulate Focal Adhesion Kinase Phosphorylation at Ser-910: REQUIREMENT FOR ERK ACTIVATION
J. Biol. Chem. 2003 278: 22631-22643. First Published on April 11, 2003; doi:10.1074/jbc.M210876200 [Abstract] [Full Text] [PDF]  

Ruma A. Pengal, Latha P. Ganesan, Huiqing Fang, Clay B. Marsh, Clark L. Anderson, and Susheela Tridandapani

SHIP-2 Inositol Phosphatase Is Inducibly Expressed in Human Monocytes and Serves to Regulate Fc Receptor-mediated Signaling
J. Biol. Chem. 2003 278: 22657-22663. First Published on April 10, 2003; doi:10.1074/jbc.M302907200 [Abstract] [Full Text] [PDF]  

Christoph Schreiter, Ruud Hovius, Matteo Costioli, Horst Pick, Stephan Kellenberger, Laurent Schild, and Horst Vogel

Characterization of the Ligand-binding Site of the Serotonin 5-HT₃ Receptor: THE ROLE OF GLUTAMATE RESIDUES 97, 224, AND 235
J. Biol. Chem. 2003 278: 22709-22716. First Published on March 26, 2003; doi:10.1074/jbc.M301801200 [Abstract] [Full Text] [PDF] Supplemental Data  

Ann L. Cornish, Mark M. Chong, Gayle M. Davey, Rima Darwiche, Nicos A. Nicola, Douglas J. Hilton, Thomas W. Kay, Robyn Starr, and Warren S. Alexander

Suppressor of Cytokine Signaling-1 Regulates Signaling in Response to Interleukin-2 and Other c-dependent Cytokines in Peripheral T Cells
J. Biol. Chem. 2003 278: 22755-22761. First Published on March 28, 2003; doi:10.1074/jbc.M303021200 [Abstract] [Full Text] [PDF]  

Nicolas Marie, Isabelle Lecoq, Philippe Jauzac, and Stéphane Allouche

Differential Sorting of Human -Opioid Receptors after Internalization by Peptide and Alkaloid Agonists
J. Biol. Chem. 2003 278: 22795-22804. First Published on April 2, 2003; doi:10.1074/jbc.M300084200 [Abstract] [Full Text] [PDF]  

Yan Zhu and Masayori Inouye

Analysis of the Role of the EnvZ Linker Region in Signal Transduction Using a Chimeric Tar/EnvZ Receptor Protein, Tez1
J. Biol. Chem. 2003 278: 22812-22819. First Published on April 2, 2003; doi:10.1074/jbc.M300916200 [Abstract] [Full Text] [PDF]  

Zhan Yin, Jennifer Haynie, Bryan R. G. Williams, and Yu-Chung Yang

C114 Is a Novel IL-11-inducible Nuclear Double-stranded RNA-binding Protein That Inhibits Protein Kinase R
J. Biol. Chem. 2003 278: 22838-22845. First Published on April 4, 2003; doi:10.1074/jbc.M212969200 [Abstract] [Full Text] [PDF]  

Elke Hessel, Martin Heck, Peter Müller, Andreas Herrmann, and Klaus Peter Hofmann

Signal Transduction in the Visual Cascade Involves Specific Lipid-Protein Interactions
J. Biol. Chem. 2003 278: 22853-22860. First Published on April 3, 2003; doi:10.1074/jbc.M302747200 [Abstract] [Full Text] [PDF]  

Wouter A. J. Nijenhuis, Keith M. Garner, Rea J. van Rozen, and Roger A. H. Adan

Poor Cell Surface Expression of Human Melanocortin-4 Receptor Mutations Associated with Obesity
J. Biol. Chem. 2003 278: 22939-22945. First Published on April 9, 2003; doi:10.1074/jbc.M211326200 [Abstract] [Full Text] [PDF]  

Hidehiko Inomata, Yoshitaka Nakamura, Akira Hayakawa, Hiroyuki Takata, Toshiharu Suzuki, Keiji Miyazawa, and Naomi Kitamura

A Scaffold Protein JIP-1b Enhances Amyloid Precursor Protein Phosphorylation by JNK and Its Association with Kinesin Light Chain 1
J. Biol. Chem. 2003 278: 22946-22955. First Published on March 28, 2003; doi:10.1074/jbc.M212160200 [Abstract] [Full Text] [PDF]  

Helena Maria Ximenes, Adama Kamagate, Françoise Van Eylen, Angelo Carpinelli, and André Herchuelz

Opposite Effects of Glucose on Plasma Membrane Ca²⁺-ATPase and Na/Ca Exchanger Transcription, Expression, and Activity in Rat Pancreatic -Cells
J. Biol. Chem. 2003 278: 22956-22963. First Published on April 7, 2003; doi:10.1074/jbc.M212339200 [Abstract] [Full Text] [PDF]  

Xian-Yong Ma, Hong Wang, Bo Ding, Haihong Zhong, Sankar Ghosh, and Peter Lengyel

The Interferon-inducible p202a Protein Modulates NF-B Activity by Inhibiting the Binding to DNA of p50/p65 Heterodimers and p65 Homodimers While Enhancing the Binding of p50 Homodimers
J. Biol. Chem. 2003 278: 23008-23019. First Published on April 3, 2003; doi:10.1074/jbc.M302105200 [Abstract] [Full Text] [PDF]  

Renee L. Doughman, Ari J. Firestone, Michelle L. Wojtasiak, Matthew W. Bunce, and Richard A. Anderson

Membrane Ruffling Requires Coordination between Type I Phosphatidylinositol Phosphate Kinase and Rac Signaling
J. Biol. Chem. 2003 278: 23036-23045. First Published on April 6, 2003; doi:10.1074/jbc.M211397200 [Abstract] [Full Text] [PDF]  

Purevsuren Jambal, Sara Masterson, Albina Nesterova, Ron Bouchard, Barbara Bergman, John C. Hutton, Linda M. Boxer, Jane E.-B. Reusch, and Subbiah Pugazhenthi

Cytokine-mediated Down-regulation of the Transcription Factor cAMP-response Element-binding Protein in Pancreatic -Cells
J. Biol. Chem. 2003 278: 23055-23065. First Published on April 5, 2003; doi:10.1074/jbc.M212450200 [Abstract] [Full Text] [PDF]  

Thomas Seck, Roland Baron, and William C. Horne

The Alternatively Spliced e13 Transcript of the Rabbit Calcitonin Receptor Dimerizes with the C1a Isoform and Inhibits Its Surface Expression
J. Biol. Chem. 2003 278: 23085-23093. First Published on April 9, 2003; doi:10.1074/jbc.M211280200 [Abstract] [Full Text] [PDF]  

Yi Chen, Joann Wu, and Gourisankar Ghosh

B-Ras Binds to the Unique Insert within the Ankyrin Repeat Domain of IB and Regulates Cytoplasmic Retention of IB·NF-B Complexes
J. Biol. Chem. 2003 278: 23101-23106. First Published on April 2, 2003; doi:10.1074/jbc.M301021200 [Abstract] [Full Text] [PDF]  

Jinping Lai, Jeremy Chien, Julie Staub, Rajeswari Avula, Eddie L. Greene, Tori A. Matthews, David I. Smith, Scott H. Kaufmann, Lewis R. Roberts**, and Viji Shridhar**

Loss of HSulf-1 Up-regulates Heparin-binding Growth Factor Signaling in Cancer
J. Biol. Chem. 2003 278: 23107-23117. First Published on April 9, 2003; doi:10.1074/jbc.M302203200 [Abstract] [Full Text] [PDF]  

Zhiyin Song, Xuebiao Yao, and Mian Wu

Direct Interaction between Survivin and Smac/DIABLO Is Essential for the Anti-apoptotic Activity of Survivin during Taxol-induced Apoptosis
J. Biol. Chem. 2003 278: 23130-23140. First Published on March 26, 2003; doi:10.1074/jbc.M300957200 [Abstract] [Full Text] [PDF]  

Wenbin Tan, Shefali Rouen, Kristin M. Barkus, Yelena S. Dremina, Dongwei Hui, Julie A. Christianson, Douglas E. Wright, Sung Ok Yoon, and Rick T. Dobrowsky

Nerve Growth Factor Blocks the Glucose-induced Down-regulation of Caveolin-1 Expression in Schwann Cells via p75 Neurotrophin Receptor Signaling
J. Biol. Chem. 2003 278: 23151-23162. First Published on April 5, 2003; doi:10.1074/jbc.M212986200 [Abstract] [Full Text] [PDF]  

Molecular Basis Of Cell and Developmental Biology:

Jane Mendel, Karie Heinecke, Henrik Fyrst, and Julie D. Saba

Sphingosine Phosphate Lyase Expression Is Essential for Normal Development in Caenorhabditis elegans
J. Biol. Chem. 2003 278: 22341-22349. First Published on April 7, 2003; doi:10.1074/jbc.M302857200 [Abstract] [Full Text] [PDF]  

Katsuyuki Shiroguchi, Miho Ohsugi, Masaki Edamatsu, Tadashi Yamamoto, and Yoko Y. Toyoshima

The Second Microtubule-binding Site of Monomeric Kid Enhances the Microtubule Affinity
J. Biol. Chem. 2003 278: 22460-22465. First Published on April 12, 2003; doi:10.1074/jbc.M212274200 [Abstract] [Full Text] [PDF] Data Supplement  

Chang Sheng Guo, Catherine Degnin, Troy A. Fiddler, Daniel Stauffer, and Mathew J. Thayer

Regulation of MyoD Activity and Muscle Cell Differentiation by MDM2, pRb, and Sp1
J. Biol. Chem. 2003 278: 22615-22622. First Published on April 17, 2003; doi:10.1074/jbc.M301943200 [Abstract] [Full Text] [PDF]  

Tineke Lauwaet, Maria José Oliveira, Bert Callewaert, Georges De Bruyne, Xavier Saelens, Serge Ankri, Peter Vandenabeele, David Mirelman, Marc Mareel, and Ancy Leroy

Proteolysis of Enteric Cell Villin by Entamoeba histolytica Cysteine Proteinases
J. Biol. Chem. 2003 278: 22650-22656. First Published on April 10, 2003; doi:10.1074/jbc.M300142200 [Abstract] [Full Text] [PDF]  

Rajnish A. Gupta, Pasha Sarraf, Elisabetta Mueller, Jeffrey A. Brockman, Jeffery J. Prusakiewicz, Charis Eng, Timothy M. Willson, and Raymond N. DuBois

Peroxisome Proliferator-activated Receptor -mediated Differentiation: A MUTATION IN COLON CANCER CELLS REVEALS DIVERGENT AND CELL TYPE-SPECIFIC MECHANISMS
J. Biol. Chem. 2003 278: 22669-22677. First Published on February 18, 2003; doi:10.1074/jbc.M300637200 [Abstract] [Full Text] [PDF]  

Shinya Yuge, Koji Inoue, Susumu Hyodo, and Yoshio Takei

A Novel Guanylin Family (Guanylin, Uroguanylin, and Renoguanylin) in Eels: POSSIBLE OSMOREGULATORY HORMONES IN INTESTINE AND KIDNEY
J. Biol. Chem. 2003 278: 22726-22733. First Published on April 8, 2003; doi:10.1074/jbc.M303111200 [Abstract] [Full Text] [PDF]  

Jennifer J. Michel, Joseph F. McCarville, and Yue Xiong

A Role for Saccharomyces cerevisiae Cul8 Ubiquitin Ligase in Proper Anaphase Progression
J. Biol. Chem. 2003 278: 22828-22837. First Published on April 3, 2003; doi:10.1074/jbc.M210358200 [Abstract] [Full Text] [PDF]  

Tansy C. Hammarton, Jade Clark, Fiona Douglas, Michael Boshart, and Jeremy C. Mottram

Stage-specific Differences in Cell Cycle Control in Trypanosoma brucei Revealed by RNA Interference of a Mitotic Cyclin
J. Biol. Chem. 2003 278: 22877-22886. First Published on April 7, 2003; doi:10.1074/jbc.M300813200 [Abstract] [Full Text] [PDF]  

Melanie A. McGill and C. Jane McGlade

Mammalian Numb Proteins Promote Notch1 Receptor Ubiquitination and Degradation of the Notch1 Intracellular Domain
J. Biol. Chem. 2003 278: 23196-23203. First Published on April 7, 2003; doi:10.1074/jbc.M302827200 [Abstract] [Full Text] [PDF]  

Ganapathy Jagatheesan, Sudarsan Rajan, Natalia Petrashevskaya, Arnold Schwartz, Greg Boivin, Susan Vahebi, Pieter DeTombe, R. John Solaro, Erin Labitzke, George Hilliard, and David F. Wieczorek

Functional Importance of the Carboxyl-terminal Region of Striated Muscle Tropomyosin
J. Biol. Chem. 2003 278: 23204-23211. First Published on April 10, 2003; doi:10.1074/jbc.M303073200 [Abstract] [Full Text] [PDF]  

Additions and Corrections:

Zhengfan Jiang, Maryam Zamanian-Daryoush, Huiqing Nie, Aristobolo M. Silva, Bryan R. G. Williams, and Xiaoxia Li

Poly(I-C)-induced Toll-like receptor 3 (TLR3)-mediated activation of NFB and MAP kinase is through an interleukin-1 receptor-associated kinase (IRAK)-independent pathway employing the signaling components TLR3-TRAF6-TAK1-TAB2-PKR
J. Biol. Chem. 2003 278: 23212. [Full Text] [PDF]  

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