Accelerated Publications:

Elizabeth A. Eckman, Mona Watson, Laura Marlow, Kumar Sambamurti, and Christopher B. Eckman

Alzheimer's Disease -Amyloid Peptide Is Increased in Mice Deficient in Endothelin-converting Enzyme
J. Biol. Chem. 2003 278: 2081-2084. First Published on December 2, 2002; 10.1074/jbc.C200642200 [Abstract] [Full Text] [PDF]  

Shima Eda, Hideaki Maseda, and Taiji Nakae

An Elegant Means of Self-protection in Gram-negative Bacteria by Recognizing and Extruding Xenobiotics from the Periplasmic Space
J. Biol. Chem. 2003 278: 2085-2088. First Published on December 1, 2002; 10.1074/jbc.C200661200 [Abstract] [Full Text] [PDF] Supplemental Data  

Stuart D. Shumway, Yong Li, and Yue Xiong

14-3-3 Binds to and Negatively Regulates the Tuberous Sclerosis Complex 2 (TSC2) Tumor Suppressor Gene Product, Tuberin
J. Biol. Chem. 2003 278: 2089-2092. First Published on December 4, 2002; 10.1074/jbc.C200499200 [Abstract] [Full Text] [PDF]  

DNA: Replication Repair and Recombination:

Hong S. Yoon, Xinming Chen, and Vincent W. Yang

Krüppel-like Factor 4 Mediates p53-dependent G₁/S Cell Cycle Arrest in Response to DNA Damage
J. Biol. Chem. 2003 278: 2101-2105. First Published on November 8, 2002; 10.1074/jbc.M211027200 [Abstract] [Full Text] [PDF]  

Graziella Cimino-Reale, Esterina Pascale, Ester Alvino, Giuseppe Starace, and Ettore D'Ambrosio

Long Telomeric C-rich 5'-Tails in Human Replicating Cells
J. Biol. Chem. 2003 278: 2136-2140. First Published on November 14, 2002; 10.1074/jbc.M208939200 [Abstract] [Full Text] [PDF]  

Elizabeth A. Stohl, Joel P. Brockman, Kristin L. Burkle, Katsumi Morimatsu, Stephen C. Kowalczykowski, and H. Steven Seifert

Escherichia coli RecX Inhibits RecA Recombinase and Coprotease Activities in Vitro and in Vivo
J. Biol. Chem. 2003 278: 2278-2285. First Published on November 9, 2002; 10.1074/jbc.M210496200 [Abstract] [Full Text] [PDF]  

Isaac Wong, Andrew S. Bernards, Jamie K. Miller, and Jacqueline A. Wirz

A Dimeric Mechanism for Contextual Target Recognition by MutY Glycosylase
J. Biol. Chem. 2003 278: 2411-2418. First Published on November 18, 2002; 10.1074/jbc.M209802200 [Abstract] [Full Text] [PDF]  

Brooke L. Heidenfelder, Alexander M. Makhov, and Michael D. Topal

Hairpin Formation in Friedreich's Ataxia Triplet Repeat Expansion
J. Biol. Chem. 2003 278: 2425-2431. First Published on November 18, 2002; 10.1074/jbc.M210643200 [Abstract] [Full Text] [PDF]  

Yi-Ching Lio, Alexander V. Mazin, Stephen C. Kowalczykowski, and David J. Chen

Complex Formation by the Human Rad51B and Rad51C DNA Repair Proteins and Their Activities in Vitro
J. Biol. Chem. 2003 278: 2469-2478. First Published on November 8, 2002; 10.1074/jbc.M211038200 [Abstract] [Full Text] [PDF]  

Hiroshi Yokoyama, Hitoshi Kurumizaka, Shukuko Ikawa, Shigeyuki Yokoyama, and Takehiko Shibata

Holliday Junction Binding Activity of the Human Rad51B Protein
J. Biol. Chem. 2003 278: 2767-2772. First Published on November 18, 2002; 10.1074/jbc.M210899200 [Abstract] [Full Text] [PDF]  

Genes: Structure and Regulation:

Thomas Kroj, Jason J. Rudd, Thorsten Nürnberger, Yvonne Gäbler, Justin Lee, and Dierk Scheel

Mitogen-activated Protein Kinases Play an Essential Role in Oxidative Burst-independent Expression of Pathogenesis-related Genes in Parsley
J. Biol. Chem. 2003 278: 2256-2264. First Published on November 7, 2002; 10.1074/jbc.M208200200 [Abstract] [Full Text] [PDF]  

Huabao Xiong, Chen Zhu, Hongxing Li, Frank Chen, Lloyd Mayer, Keiko Ozato, Jay C. Unkeless, and Scott E. Plevy

Complex Formation of the Interferon (IFN) Consensus Sequence-binding Protein with IRF-1 Is Essential for Murine Macrophage IFN--induced iNOS Gene Expression
J. Biol. Chem. 2003 278: 2271-2277. First Published on November 11, 2002; 10.1074/jbc.M209583200 [Abstract] [Full Text] [PDF]  

Ping Sun and Horace H. Loh

Transcriptional Regulation of Mouse -Opioid Receptor Gene. IKAROS-2 AND UPSTREAM STIMULATORY FACTOR SYNERGIZE IN TRANS-ACTIVATING MOUSE -OPIOID RECEPTOR GENE IN T CELLS
J. Biol. Chem. 2003 278: 2304-2308. First Published on November 12, 2002; 10.1074/jbc.M208162200 [Abstract] [Full Text] [PDF]  

Chunhong Yan, Heng Wang, Yasushi Toh, and Douglas D. Boyd

Repression of 92-kDa Type IV Collagenase Expression by MTA1 Is Mediated through Direct Interactions with the Promoter via a Mechanism, Which Is Both Dependent on and Independent of Histone Deacetylation
J. Biol. Chem. 2003 278: 2309-2316. First Published on November 12, 2002; 10.1074/jbc.M210369200 [Abstract] [Full Text] [PDF]  

Alejandra S. Guberman, María E. Scassa, Luciana E. Giono, Cecilia L. Varone, and Eduardo T. Cánepa

Inhibitory Effect of AP-1 Complex on 5-Aminolevulinate Synthase Gene Expression through Sequestration of cAMP-response Element Protein (CRE)-binding Protein (CBP) Coactivator
J. Biol. Chem. 2003 278: 2317-2326. First Published on November 13, 2002; 10.1074/jbc.M205057200 [Abstract] [Full Text] [PDF]  

E. Christine Pietsch, Jefferson Y. Chan, Frank M. Torti, and Suzy V. Torti

Nrf2 Mediates the Induction of Ferritin H in Response to Xenobiotics and Cancer Chemopreventive Dithiolethiones
J. Biol. Chem. 2003 278: 2361-2369. First Published on November 14, 2002; 10.1074/jbc.M210664200 [Abstract] [Full Text] [PDF]  

Astrid Borchert, Nicolai E. Savaskan, and Hartmut Kuhn

Regulation of Expression of the Phospholipid Hydroperoxide/Sperm Nucleus Glutathione Peroxidase Gene. TISSUE-SPECIFIC EXPRESSION PATTERN AND IDENTIFICATION OF FUNCTIONAL CIS- AND TRANS-REGULATORY ELEMENTS
J. Biol. Chem. 2003 278: 2571-2580. First Published on November 8, 2002; 10.1074/jbc.M209064200 [Abstract] [Full Text] [PDF]  

RNA: Structure Metabolism and Catalysis:

Joanna Kufel, Christine Allmang, Elisabeth Petfalski, Jean Beggs, and David Tollervey

Lsm Proteins Are Required for Normal Processing and Stability of Ribosomal RNAs
J. Biol. Chem. 2003 278: 2147-2156. First Published on November 15, 2002; 10.1074/jbc.M208856200 [Abstract] [Full Text] [PDF]  

Eric Ennifar, Jean-Christophe Paillart, Roland Marquet, Bernard Ehresmann, Chantal Ehresmann, Philippe Dumas, and Philippe Walter

HIV-1 RNA Dimerization Initiation Site Is Structurally Similar to the Ribosomal A Site and Binds Aminoglycoside Antibiotics
J. Biol. Chem. 2003 278: 2723-2730. First Published on November 14, 2002; 10.1074/jbc.M205726200 [Abstract] [Full Text] [PDF] Supplemental Data  

Protein Synthesis Post-Translation Modification and Degradation:

Michael T. Overgaard, Esben S. Sørensen, Damian Stachowiak, Henning B. Boldt, Lene Kristensen, Lars Sottrup-Jensen, and Claus Oxvig

Complex of Pregnancy-associated Plasma Protein-A and the Proform of Eosinophil Major Basic Protein. DISULFIDE STRUCTURE AND CARBOHYDRATE ATTACHMENT SITES
J. Biol. Chem. 2003 278: 2106-2117. First Published on November 5, 2002; 10.1074/jbc.M208777200 [Abstract] [Full Text] [PDF]  

Claudia Marquordt, Qinghua Fang, Elke Will, Jianhe Peng, Kurt von Figura, and Thomas Dierks

Posttranslational Modification of Serine to Formylglycine in Bacterial Sulfatases. RECOGNITION OF THE MODIFICATION MOTIF BY THE IRON-SULFUR PROTEIN AtsB
J. Biol. Chem. 2003 278: 2212-2218. First Published on November 4, 2002; 10.1074/jbc.M209435200 [Abstract] [Full Text] [PDF]  

Hakuto Kageyama, Takao Kondo, and Hideo Iwasaki

Circadian Formation of Clock Protein Complexes by KaiA, KaiB, KaiC, and SasA in Cyanobacteria
J. Biol. Chem. 2003 278: 2388-2395. First Published on November 18, 2002; 10.1074/jbc.M208899200 [Abstract] [Full Text] [PDF]  

Daniel Stewart, Erin Killeen, Ryan Naquin, Safdar Alam, and Jawed Alam

Degradation of Transcription Factor Nrf2 via the Ubiquitin-Proteasome Pathway and Stabilization by Cadmium
J. Biol. Chem. 2003 278: 2396-2402. First Published on November 18, 2002; 10.1074/jbc.M209195200 [Abstract] [Full Text] [PDF]  

Alan D. Winter, Johanna Myllyharju, and Antony P. Page

A Hypodermally Expressed Prolyl 4-Hydroxylase from the Filarial Nematode Brugia malayi Is Soluble and Active in the Absence of Protein Disulfide Isomerase
J. Biol. Chem. 2003 278: 2554-2562. First Published on November 1, 2002; 10.1074/jbc.M210381200 [Abstract] [Full Text] [PDF]  

Rosemary Kiernan, Vanessa Brès, Raymond W. M. Ng, Marie-Pierre Coudart, Selma El Messaoudi, Claude Sardet, Dong-Yan Jin, Stephane Emiliani, and Monsef Benkirane

Post-activation Turn-off of NF-B-dependent Transcription Is Regulated by Acetylation of p65
J. Biol. Chem. 2003 278: 2758-2766. First Published on November 4, 2002; 10.1074/jbc.M209572200 [Abstract] [Full Text] [PDF]  

Protein Structure and Folding:

Alain R. Baulard, Sudagar S. Gurcha, Jean Engohang-Ndong, Kamila Gouffi, Camille Locht, and Gurdyal S. Besra

In Vivo Interaction between the Polyprenol Phosphate Mannose Synthase Ppm1 and the Integral Membrane Protein Ppm2 from Mycobacterium smegmatis Revealed by a Bacterial Two-hybrid System
J. Biol. Chem. 2003 278: 2242-2248. First Published on November 8, 2002; 10.1074/jbc.M207922200 [Abstract] [Full Text] [PDF] Supplemental Data  

Richard D. Brokx, Eleonora Bolewska-Pedyczak, and Jean Gariépy

A Stable Human p53 Heterotetramer Based on Constructive Charge Interactions within the Tetramerization Domain
J. Biol. Chem. 2003 278: 2327-2332. First Published on November 13, 2002; 10.1074/jbc.M208528200 [Abstract] [Full Text] [PDF]  

Alexander Kukarin, Minqing Rong, and William T. McAllister

Exposure of T7 RNA Polymerase to the Isolated Binding Region of the Promoter Allows Transcription from a Single-stranded Template
J. Biol. Chem. 2003 278: 2419-2424. First Published on November 18, 2002; 10.1074/jbc.M210058200 [Abstract] [Full Text] [PDF]  

Youde Mo, Begoña Campos, Tanya R. Mealy, Lois Commodore, James F. Head, John R. Dedman, and Barbara A. Seaton

Interfacial Basic Cluster in Annexin V Couples Phospholipid Binding and Trimer Formation on Membrane Surfaces
J. Biol. Chem. 2003 278: 2437-2443. First Published on October 24, 2002; 10.1074/jbc.M210286200 [Abstract] [Full Text] [PDF]  

Alessia Andreola, Vittorio Bellotti, Sofia Giorgetti, Palma Mangione, Laura Obici, Monica Stoppini, Jaume Torres, Enrico Monzani, Giampaolo Merlini, and Margaret Sunde

Conformational Switching and Fibrillogenesis in the Amyloidogenic Fragment of Apolipoprotein A-I
J. Biol. Chem. 2003 278: 2444-2451. First Published on November 5, 2002; 10.1074/jbc.M204801200 [Abstract] [Full Text] [PDF]  

Guangyu Zhu, Jian Liu, Simon Terzyan, Peng Zhai, Guangpu Li, and Xuejun C. Zhang

High Resolution Crystal Structures of Human Rab5a and Five Mutants with Substitutions in the Catalytically Important Phosphate-binding Loop
J. Biol. Chem. 2003 278: 2452-2460. First Published on November 13, 2002; 10.1074/jbc.M211042200 [Abstract] [Full Text] [PDF]  

Henri R. Nordlund, Olli H. Laitinen, Sanna T. H. Uotila, Thomas Nyholm, Vesa P. Hytönen, J. Peter Slotte, and Markku S. Kulomaa

Enhancing the Thermal Stability of Avidin. INTRODUCTION OF DISULFIDE BRIDGES BETWEEN SUBUNIT INTERFACES
J. Biol. Chem. 2003 278: 2479-2483. First Published on November 20, 2002; 10.1074/jbc.M210721200 [Abstract] [Full Text] [PDF]  

Maolin Guo, Ian Harvey, Weiping Yang, Lorraine Coghill, Dominic J. Campopiano, John A. Parkinson, Ross T. A. MacGillivray, Wesley R. Harris, and Peter J. Sadler

Synergistic Anion and Metal Binding to the Ferric Ion-binding Protein from Neisseria gonorrhoeae
J. Biol. Chem. 2003 278: 2490-2502. First Published on October 7, 2002; 10.1074/jbc.M208776200 [Abstract] [Full Text] [PDF] Supplemental Data  

Jiu-Li Song, Jun Li, Yi-Shuian Huang, and David T. Chuang

Encapsulation of an 86-kDa Assembly Intermediate inside the Cavities of GroEL and Its Single-ring Variant SR1 by GroES
J. Biol. Chem. 2003 278: 2515-2521. First Published on November 12, 2002; 10.1074/jbc.M209705200 [Abstract] [Full Text] [PDF]  

Greg P. Bertenshaw, Mona T. Norcum, and Judith S. Bond

Structure of Homo- and Hetero-oligomeric Meprin Metalloproteases. DIMERS, TETRAMERS, AND HIGH MOLECULAR MASS MULTIMERS
J. Biol. Chem. 2003 278: 2522-2532. First Published on October 23, 2002; 10.1074/jbc.M208808200 [Abstract] [Full Text] [PDF]  

R. Scott Williams and J. N. Mark Glover

Structural Consequences of a Cancer-causing BRCA1-BRCT Missense Mutation
J. Biol. Chem. 2003 278: 2630-2635. First Published on November 8, 2002; 10.1074/jbc.M210019200 [Abstract] [Full Text] [PDF]  

Peijian Zou, Mathias Gautel, Arie Geerlof, Matthias Wilmanns, Michel H. J. Koch, and Dmitri I. Svergun

Solution Scattering Suggests Cross-linking Function of Telethonin in the Complex with Titin
J. Biol. Chem. 2003 278: 2636-2644. First Published on November 20, 2002; 10.1074/jbc.M210217200 [Abstract] [Full Text] [PDF]  

Tzu-Fun Fu, J. Neel Scarsdale, Galina Kazanina, Verne Schirch, and H. Tonie Wright

Location of the Pteroylpolyglutamate-binding Site on Rabbit Cytosolic Serine Hydroxymethyltransferase
J. Biol. Chem. 2003 278: 2645-2653. First Published on November 15, 2002; 10.1074/jbc.M210649200 [Abstract] [Full Text] [PDF]  

Akira Hosoda, Yukio Kimata, Akio Tsuru, and Kenji Kohno

JPDI, a Novel Endoplasmic Reticulum-resident Protein Containing Both a BiP-interacting J-domain and Thioredoxin-like Motifs
J. Biol. Chem. 2003 278: 2669-2676. First Published on November 20, 2002; 10.1074/jbc.M208346200 [Abstract] [Full Text] [PDF]  

Enzyme Catalysis and Regulation:

Ling Xia, Tomas Nordman, Jerker M. Olsson, Anastassios Damdimopoulos, Linda Björkhem-Bergman, Ivan Nalvarte, Lennart C. Eriksson, Elias S. J. Arnér, Giannis Spyrou, and Mikael Björnstedt

The Mammalian Cytosolic Selenoenzyme Thioredoxin Reductase Reduces Ubiquinone. A NOVEL MECHANISM FOR DEFENSE AGAINST OXIDATIVE STRESS
J. Biol. Chem. 2003 278: 2141-2146. First Published on November 14, 2002; 10.1074/jbc.M210456200 [Abstract] [Full Text] [PDF]  

Jinling Wang, Shen Lu, Pierre Moënne-Loccoz, and Paul R. Ortiz de Montellano

Interaction of Nitric Oxide with Human Heme Oxygenase-1
J. Biol. Chem. 2003 278: 2341-2347. First Published on November 13, 2002; 10.1074/jbc.M211131200 [Abstract] [Full Text] [PDF]  

Tianhui Hu and John H. Exton

Mechanisms of Regulation of Phospholipase D1 by Protein Kinase C
J. Biol. Chem. 2003 278: 2348-2355. First Published on November 12, 2002; 10.1074/jbc.M210093200 [Abstract] [Full Text] [PDF]  

Mullika Traidej, Mary E. Marquart, Armando R. Caballero, Brett A. Thibodeaux, and Richard J. O'Callaghan

Identification of the Active Site Residues of Pseudomonas aeruginosa Protease IV. IMPORTANCE OF ENZYME ACTIVITY IN AUTOPROCESSING AND ACTIVATION
J. Biol. Chem. 2003 278: 2549-2553. First Published on November 4, 2002; 10.1074/jbc.M208973200 [Abstract] [Full Text] [PDF]  

Metabolism and Bioenergetics:

Yungang Zhao, Zhi-Bo Wang, and Jian-Xing Xu

Effect of Cytochrome c on the Generation and Elimination of O₂^- and H₂O₂ in Mitochondria
J. Biol. Chem. 2003 278: 2356-2360. First Published on November 14, 2002; 10.1074/jbc.M209681200 [Abstract] [Full Text] [PDF]  

Jeffrey Thomas, Kelli S. Bramlett, Chahrzad Montrose, Patricia Foxworthy, Patrick I. Eacho, Denis McCann, Guoqing Cao, Anton Kiefer, Jeff McCowan, Kuo-long Yu, Timothy Grese, William W. Chin, Thomas P. Burris, and Laura F. Michael

A Chemical Switch Regulates Fibrate Specificity for Peroxisome Proliferator-activated Receptor (PPAR) Versus Liver X Receptor
J. Biol. Chem. 2003 278: 2403-2410. First Published on November 18, 2002; 10.1074/jbc.M209629200 [Abstract] [Full Text] [PDF]  

Toshimasa Yamauchi, Junji Kamon, Hironori Waki, Yasushi Imai, Nobuhiro Shimozawa, Kyouji Hioki, Shoko Uchida, Yusuke Ito, Keisuke Takakuwa, Junji Matsui, Makoto Takata, Kazuhiro Eto, Yasuo Terauchi, Kajuro Komeda, Masaki Tsunoda, Koji Murakami, Yasuyuki Ohnishi, Takeshi Naitoh, Kenichi Yamamura, Yoshito Ueyama, Philippe Froguel, Satoshi Kimura, Ryozo Nagai, and Takashi Kadowaki

Globular Adiponectin Protected ob/ob Mice from Diabetes and ApoE-deficient Mice from Atherosclerosis
J. Biol. Chem. 2003 278: 2461-2468. First Published on November 12, 2002; 10.1074/jbc.M209033200 [Abstract] [Full Text] [PDF]  

Sucharita Sen Banerjee, Mark W. Feinberg, Masafumi Watanabe, Susan Gray, Richard L. Haspel, Diane J. Denkinger, Rodney Kawahara, Hans Hauner, and Mukesh K. Jain

The Krüppel-like Factor KLF2 Inhibits Peroxisome Proliferator-activated Receptor- Expression and Adipogenesis
J. Biol. Chem. 2003 278: 2581-2584. First Published on November 7, 2002; 10.1074/jbc.M210859200 [Abstract] [Full Text] [PDF]  

Patrice P. Hamel, Beth Welty Dreyfuss, Zhiyi Xie, Stéphane T. Gabilly, and Sabeeha Merchant

Essential Histidine and Tryptophan Residues in CcsA, a System II Polytopic Cytochrome c Biogenesis Protein
J. Biol. Chem. 2003 278: 2593-2603. First Published on November 9, 2002; 10.1074/jbc.M208651200 [Abstract] [Full Text] [PDF] Supplemental Data  

Beth Welty Dreyfuss, Patrice P. Hamel, Stacie S. Nakamoto, and Sabeeha Merchant

Functional Analysis of a Divergent System II Protein, Ccs1, Involved in c-Type Cytochrome Biogenesis
J. Biol. Chem. 2003 278: 2604-2613. First Published on November 9, 2002; 10.1074/jbc.M208652200 [Abstract] [Full Text] [PDF] Supplemental Data  

Glycobiology and Extracellular Matrices:

Stacey Klutts, Irena Pastuszak, Vineetha Koroth Edavana, Prajitha Thampi, Yuan-Tseng Pan, Edathera C. Abraham, J. David Carroll, and Alan D. Elbein

Purification, Cloning, Expression, and Properties of Mycobacterial Trehalose-phosphate Phosphatase
J. Biol. Chem. 2003 278: 2093-2100. First Published on November 1, 2002; 10.1074/jbc.M209937200 [Abstract] [Full Text] [PDF]  

Noe L. Charbonneau, Bette J. Dzamba, Robert N. Ono, Douglas R. Keene, Glen M. Corson, Dieter P. Reinhardt, and Lynn Y. Sakai

Fibrillins Can Co-assemble in Fibrils, but Fibrillin Fibril Composition Displays Cell-specific Differences
J. Biol. Chem. 2003 278: 2740-2749. First Published on November 11, 2002; 10.1074/jbc.M209201200 [Abstract] [Full Text] [PDF]  

Zenzo Isogai, Robert N. Ono, Shin Ushiro, Douglas R. Keene, Yan Chen, Roberta Mazzieri, Noe L. Charbonneau, Dieter P. Reinhardt, Daniel B. Rifkin, and Lynn Y. Sakai

Latent Transforming Growth Factor -binding Protein 1 Interacts with Fibrillin and Is a Microfibril-associated Protein
J. Biol. Chem. 2003 278: 2750-2757. First Published on November 11, 2002; 10.1074/jbc.M209256200 [Abstract] [Full Text] [PDF]  

Lipids and Lipoproteins:

Gilles Lambert, Marcelo J. A. Amar, Grace Guo, H. Bryan Brewer, Jr., Frank J. Gonzalez, and Christopher J. Sinal

The Farnesoid X-receptor Is an Essential Regulator of Cholesterol Homeostasis
J. Biol. Chem. 2003 278: 2563-2570. First Published on November 5, 2002; 10.1074/jbc.M209525200 [Abstract] [Full Text] [PDF]  

Membrane Transport Structure Function and Biogenesis:

Fouzia Shoeb, Anna P. Malykhina, and Hamid I. Akbarali

Cloning and Functional Characterization of the Smooth Muscle Ether-a-go-go-related Gene K⁺ Channel. POTENTIAL ROLE OF A CONSERVED AMINO ACID SUBSTITUTION IN THE S4 REGION
J. Biol. Chem. 2003 278: 2503-2514. First Published on November 9, 2002; 10.1074/jbc.M208525200 [Abstract] [Full Text] [PDF]  

Christof Grewer, Natalie Watzke, Thomas Rauen, and Ana Bicho

Is the Glutamate Residue Glu-373 the Proton Acceptor of the Excitatory Amino Acid Carrier 1?
J. Biol. Chem. 2003 278: 2585-2592. First Published on November 4, 2002; 10.1074/jbc.M207956200 [Abstract] [Full Text] [PDF]  

Shao-Xiong Wang, Masahiro Ikeda, and William B. Guggino

The Cytoplasmic Tail of Large Conductance, Voltage- and Ca²⁺-activated K⁺ (MaxiK) Channel Is Necessary for Its Cell Surface Expression
J. Biol. Chem. 2003 278: 2713-2722. First Published on November 15, 2002; 10.1074/jbc.M208411200 [Abstract] [Full Text] [PDF]  

Gonzalo E. Torres, Ana Carneiro, Katie Seamans, Chiara Fiorentini, Ava Sweeney, Wei-Dong Yao, and Marc G. Caron

Oligomerization and Trafficking of the Human Dopamine Transporter. MUTATIONAL ANALYSIS IDENTIFIES CRITICAL DOMAINS IMPORTANT FOR THE FUNCTIONAL EXPRESSION OF THE TRANSPORTER
J. Biol. Chem. 2003 278: 2731-2739. First Published on November 11, 2002; 10.1074/jbc.M201926200 [Abstract] [Full Text] [PDF]  

Mechanisms Of Signal Transduction:

M. Page Haynes, Lei Li, Diviya Sinha, Kerry S. Russell, Koji Hisamoto, Roland Baron, Mark Collinge, William C. Sessa, and Jeffrey R. Bender

Src Kinase Mediates Phosphatidylinositol 3-Kinase/Akt-dependent Rapid Endothelial Nitric-oxide Synthase Activation by Estrogen
J. Biol. Chem. 2003 278: 2118-2123. First Published on November 12, 2002; 10.1074/jbc.M210828200 [Abstract] [Full Text] [PDF]  

Guangming Liu, Wei-Ya Ma, Ann M. Bode, Yiguo Zhang, and Zigang Dong

NS-398 and Piroxicam Suppress UVB-induced Activator Protein 1 Activity by Mechanisms Independent of Cyclooxygenase-2
J. Biol. Chem. 2003 278: 2124-2130. First Published on November 13, 2002; 10.1074/jbc.M202443200 [Abstract] [Full Text] [PDF]  

Sara Yoon, Zhengchang Liu, Yvonne Eyobo, and Kim Orth

Yersinia Effector YopJ Inhibits Yeast MAPK Signaling Pathways by an Evolutionarily Conserved Mechanism
J. Biol. Chem. 2003 278: 2131-2135. First Published on November 13, 2002; 10.1074/jbc.M209905200 [Abstract] [Full Text] [PDF]  

Michael Ferber, Annett Sporning, Gunnar Jeserich, Richard DeLaCruz, Maren Watkins, Baldomero M. Olivera, and Heinrich Terlau

A Novel Conus Peptide Ligand for K⁺ Channels
J. Biol. Chem. 2003 278: 2177-2183. First Published on October 23, 2002; 10.1074/jbc.M205953200 [Abstract] [Full Text] [PDF]  

Beatrix Pollok-Kopp, Katrin Schwarze, Viola Katharina Baradari, and Martin Oppermann

Analysis of Ligand-stimulated CC Chemokine Receptor 5 (CCR5) Phosphorylation in Intact Cells Using Phosphosite-specific Antibodies
J. Biol. Chem. 2003 278: 2190-2198. First Published on October 27, 2002; 10.1074/jbc.M209844200 [Abstract] [Full Text] [PDF]  

Claudia Graciela Buitrago, Verónica González Pardo, Ana R. de Boland, and Ricardo Boland

Activation of RAF-1 through Ras and Protein Kinase C Mediates 1,25(OH)₂-Vitamin D₃ Regulation of the Mitogen-activated Protein Kinase Pathway in Muscle Cells
J. Biol. Chem. 2003 278: 2199-2205. First Published on November 1, 2002; 10.1074/jbc.M205732200 [Abstract] [Full Text] [PDF]  

Hitoshi Saito, Kenichiro Kusano, Masahiko Kinosaki, Hirotaka Ito, Michinori Hirata, Hiroko Segawa, Ken-ichi Miyamoto, and Naoshi Fukushima

Human Fibroblast Growth Factor-23 Mutants Suppress Na⁺-dependent Phosphate Co-transport Activity and 1,25-Dihydroxyvitamin D₃ Production
J. Biol. Chem. 2003 278: 2206-2211. First Published on November 4, 2002; 10.1074/jbc.M207872200 [Abstract] [Full Text] [PDF]  

Audrey Varin, Sunil K. Manna, Vincent Quivy, Anne-Zélie Decrion, Carine Van Lint, Georges Herbein, and Bharat B. Aggarwal

Exogenous Nef Protein Activates NF-B, AP-1, and c-Jun N-Terminal Kinase and Stimulates HIV Transcription in Promonocytic Cells. ROLE IN AIDS PATHOGENESIS
J. Biol. Chem. 2003 278: 2219-2227. First Published on November 4, 2002; 10.1074/jbc.M209622200 [Abstract] [Full Text] [PDF]  

Sanjin Zvonic, Peter Cornelius, William C. Stewart, Randall L. Mynatt, and Jacqueline M. Stephens

The Regulation and Activation of Ciliary Neurotrophic Factor Signaling Proteins in Adipocytes
J. Biol. Chem. 2003 278: 2228-2235. First Published on November 6, 2002; 10.1074/jbc.M205871200 [Abstract] [Full Text] [PDF]  

Wendy J. Freebern, James L. Smith, Sohail S. Chaudhry, Cynthia M. Haggerty, and Kevin Gardner

Novel Cell-specific and Dominant Negative Anti-apoptotic Roles of p73 in Transformed Leukemia Cells
J. Biol. Chem. 2003 278: 2249-2255. First Published on November 8, 2002; 10.1074/jbc.M208517200 [Abstract] [Full Text] [PDF] Supplemental Data  

Janeen H. Trembley, Dongli Hu, Clive A. Slaughter, Jill M. Lahti, and Vincent J. Kidd

Casein Kinase 2 Interacts with Cyclin-dependent Kinase 11 (CDK11) in Vivo and Phosphorylates Both the RNA Polymerase II Carboxyl-terminal Domain and CDK11 in Vitro
J. Biol. Chem. 2003 278: 2265-2270. First Published on November 11, 2002; 10.1074/jbc.M207518200 [Abstract] [Full Text] [PDF]  

Baoxue Ge, Xinsheng Xiong, Qing Jing, Jennifer L. Mosley, Angela Filose, Dafang Bian, Shuang Huang, and Jiahuai Han

TAB1 (Transforming Growth Factor--activated Protein Kinase 1-binding Protein 1), a Novel Splicing Variant of TAB1 That Interacts with p38 but Not TAK1
J. Biol. Chem. 2003 278: 2286-2293. First Published on November 11, 2002; 10.1074/jbc.M210918200 [Abstract] [Full Text] [PDF]  

Katherine J. Ladner, Michael A. Caligiuri, and Denis C. Guttridge

Tumor Necrosis Factor-regulated Biphasic Activation of NF-B Is Required for Cytokine-induced Loss of Skeletal Muscle Gene Products
J. Biol. Chem. 2003 278: 2294-2303. First Published on November 12, 2002; 10.1074/jbc.M207129200 [Abstract] [Full Text] [PDF]  

Hwan Youn, Robert L. Kerby, and Gary P. Roberts

The Role of the Hydrophobic Distal Heme Pocket of CooA in Ligand Sensing and Response
J. Biol. Chem. 2003 278: 2333-2340. First Published on November 13, 2002; 10.1074/jbc.M210825200 [Abstract] [Full Text] [PDF]  

Stephan Klöß, Henry Furneaux, and Alexander Mülsch

Post-transcriptional Regulation of Soluble Guanylyl Cyclase Expression in Rat Aorta
J. Biol. Chem. 2003 278: 2377-2383. First Published on November 18, 2002; 10.1074/jbc.M206453200 [Abstract] [Full Text] [PDF]  

Bo Liu and Dianqing Wu

The First Inner Loop of Endothelin Receptor Type B Is Necessary for Specific Coupling to G₁₃
J. Biol. Chem. 2003 278: 2384-2387. First Published on November 18, 2002; 10.1074/jbc.M208683200 [Abstract] [Full Text] [PDF]  

Atsuo Sasaki, Kyoko Inagaki-Ohara, Takafumi Yoshida, Atsushi Yamanaka, Mika Sasaki, Hideo Yasukawa, Antonis E. Koromilas, and Akihiko Yoshimura

The N-terminal Truncated Isoform of SOCS3 Translated from an Alternative Initiation AUG Codon under Stress Conditions Is Stable Due to the Lack of a Major Ubiquitination Site, Lys-6
J. Biol. Chem. 2003 278: 2432-2436. First Published on November 28, 2002; 10.1074/jbc.C200608200 [Abstract] [Full Text] [PDF]  

Jochen Herms, Ilka Schneider, Ilse Dewachter, Nathalie Caluwaerts, Hans Kretzschmar, and Fred Van Leuven

Capacitive Calcium Entry Is Directly Attenuated by Mutant Presenilin-1, Independent of the Expression of the Amyloid Precursor Protein
J. Biol. Chem. 2003 278: 2484-2489. First Published on November 12, 2002; 10.1074/jbc.M206769200 [Abstract] [Full Text] [PDF]  

Robin Ketteler, Chetal S. Moghraby, Jonathan G. Hsiao, Olivier Sandra, Harvey F. Lodish, and Ursula Klingmüller

The Cytokine-inducible Scr Homology Domain-containing Protein Negatively Regulates Signaling by Promoting Apoptosis in Erythroid Progenitor Cells
J. Biol. Chem. 2003 278: 2654-2660. First Published on November 18, 2002; 10.1074/jbc.M211236200 [Abstract] [Full Text] [PDF]  

Sung-Woo Kim, Masaaki Hayashi, Jeng-Fan Lo, Young Yang, Jin-San Yoo, and Jiing-Dwan Lee

ADP-ribosylation Factor 4 Small GTPase Mediates Epidermal Growth Factor Receptor-dependent Phospholipase D2 Activation
J. Biol. Chem. 2003 278: 2661-2668. First Published on November 21, 2002; 10.1074/jbc.M205819200 [Abstract] [Full Text] [PDF]  

John R. Petrulis, Ann Kusnadi, Preeti Ramadoss, Brett Hollingshead, and Gary H. Perdew

The hsp90 Co-chaperone XAP2 Alters Importin Recognition of the Bipartite Nuclear Localization Signal of the Ah Receptor and Represses Transcriptional Activity
J. Biol. Chem. 2003 278: 2677-2685. First Published on November 12, 2002; 10.1074/jbc.M209331200 [Abstract] [Full Text] [PDF]  

Mahnaz Razandi, Ali Pedram, Steven T. Park, and Ellis R. Levin

Proximal Events in Signaling by Plasma Membrane Estrogen Receptors
J. Biol. Chem. 2003 278: 2701-2712. First Published on November 5, 2002; 10.1074/jbc.M205692200 [Abstract] [Full Text] [PDF]  

Molecular Basis Of Cell and Developmental Biology:

Marleen M. R. Petit, Sandra M. P. Meulemans, and Wim J. M. Van de Ven

The Focal Adhesion and Nuclear Targeting Capacity of the LIM-containing Lipoma-preferred Partner (LPP) Protein
J. Biol. Chem. 2003 278: 2157-2168. First Published on November 18, 2002; 10.1074/jbc.M206106200 [Abstract] [Full Text] [PDF]  

Takashi Inaoka, Kosaku Takahashi, Mayumi Ohnishi-Kameyama, Mitsuru Yoshida, and Kozo Ochi

Guanine Nucleotides Guanosine 5'-Diphosphate 3'-Diphosphate and GTP Co-operatively Regulate the Production of an Antibiotic Bacilysin in Bacillus subtilis
J. Biol. Chem. 2003 278: 2169-2176. First Published on October 7, 2002; 10.1074/jbc.M208722200 [Abstract] [Full Text] [PDF]  

Nadheige Lochard, David W. Silversides, Jorge P. van Kats, Chantal Mercure, and Timothy L. Reudelhuber

Brain-specific Restoration of Angiotensin II Corrects Renal Defects Seen in Angiotensinogen-deficient Mice
J. Biol. Chem. 2003 278: 2184-2189. First Published on October 23, 2002; 10.1074/jbc.M209933200 [Abstract] [Full Text] [PDF]  

Anna Castro, Elisabeth Mandart, Thierry Lorca, and Simon Galas

Involvement of Aurora A Kinase during Meiosis I-II Transition in Xenopus Oocytes
J. Biol. Chem. 2003 278: 2236-2241. First Published on November 7, 2002; 10.1074/jbc.M207894200 [Abstract] [Full Text] [PDF]  

Curtis Bradney, Mark Hjelmeland, Yasuhiko Komatsu, Minoru Yoshida, Tso-Pang Yao, and Yuan Zhuang

Regulation of E2A Activities by Histone Acetyltransferases in B Lymphocyte Development
J. Biol. Chem. 2003 278: 2370-2376. First Published on November 14, 2002; 10.1074/jbc.M211464200 [Abstract] [Full Text] [PDF]  

David S. Reiner, Michael L. Hetsko, J. Gary Meszaros, Chin-Hung Sun, Hilary G. Morrison, Laurence L. Brunton, and Frances D. Gillin

Calcium Signaling in Excystation of the Early Diverging Eukaryote, Giardia lamblia
J. Biol. Chem. 2003 278: 2533-2540. First Published on October 22, 2002; 10.1074/jbc.M208033200 [Abstract] [Full Text] [PDF]  

Huifei Liu, Ferdinando Di Cunto, Sara Imarisio, and Lola M. Reid

Citron Kinase Is a Cell Cycle-dependent, Nuclear Protein Required for G₂/M Transition of Hepatocytes
J. Biol. Chem. 2003 278: 2541-2548. First Published on October 30, 2002; 10.1074/jbc.M210391200 [Abstract] [Full Text] [PDF]  

Tony J. C. Harris, Amir Ravandi, Donald E. Awrey, and Chi-Hung Siu

Cytoskeleton Interactions Involved in the Assembly and Function of Glycoprotein-80 Adhesion Complexes in Dictyostelium
J. Biol. Chem. 2003 278: 2614-2623. First Published on November 5, 2002; 10.1074/jbc.M206241200 [Abstract] [Full Text] [PDF]  

Jae-Ran Lee, Hyewon Shin, Jaewon Ko, Jeonghoon Choi, Hane Lee, and Eunjoon Kim

Characterization of the Movement of the Kinesin Motor KIF1A in Living Cultured Neurons
J. Biol. Chem. 2003 278: 2624-2629. First Published on November 14, 2002; 10.1074/jbc.M211152200 [Abstract] [Full Text] [PDF] Supplemental Data  

Carlos M. Luque, Carmen M. Pérez-Ferreiro, Alicia Pérez-González, Ludwig Englmeier, Maria D. Koffa, and Isabel Correas

An Alternative Domain Containing a Leucine-rich Sequence Regulates Nuclear Cytoplasmic Localization of Protein 4.1R
J. Biol. Chem. 2003 278: 2686-2691. First Published on November 9, 2002; 10.1074/jbc.M201521200 [Abstract] [Full Text] [PDF]  

Andreas Traweger, Renate Fuchs, Istvan A. Krizbai, Thomas M. Weiger, Hans-Christian Bauer, and Hannelore Bauer

The Tight Junction Protein ZO-2 Localizes to the Nucleus and Interacts with the Heterogeneous Nuclear Ribonucleoprotein Scaffold Attachment Factor-B
J. Biol. Chem. 2003 278: 2692-2700. First Published on October 27, 2002; 10.1074/jbc.M206821200 [Abstract] [Full Text] [PDF]  

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