JBC DNA damage antibodies

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Table of Contents: Jan 31 2003; 278 (5)   [Index by Author]  [Cover Figure and Caption]
       Accelerated Publications
       DNA: Replication Repair and Recombination
       Genes: Structure and Regulation
       RNA: Structure Metabolism and Catalysis
       Protein Synthesis Post-Translation Modification and Degradation
       Genomics Proteomics and Bioinformatics
       Protein Structure and Folding
       Enzyme Catalysis and Regulation
       Metabolism and Bioenergetics
       Glycobiology and Extracellular Matrices
       Lipids and Lipoproteins
       Membrane Transport Structure Function and Biogenesis
       Mechanisms Of Signal Transduction
       Molecular Basis Of Cell and Developmental Biology
       Additions and Corrections
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Accelerated Publications:

Byeong-Churl Jang, Ursula Muñoz-Najar, Ji-Hye Paik, Kevin Claffey, Minoru Yoshida, and Timothy Hla
Leptomycin B, an Inhibitor of the Nuclear Export Receptor CRM1, Inhibits COX-2 Expression
J. Biol. Chem. 2003 278: 2773-2776. First Published on December 4, 2002; doi:10.1074/jbc.C200620200 [Abstract] [Full Text] [PDF]  

Cathryn A. Shaw-Reid, Vandna Munshi, Pia Graham, Abigail Wolfe, Marc Witmer, Renee Danzeisen, David B. Olsen, Steven S. Carroll, Mark Embrey, John S. Wai, Michael D. Miller, James L. Cole, and Daria J. Hazuda
Inhibition of HIV-1 Ribonuclease H by a Novel Diketo Acid, 4-[5-(Benzoylamino)thien-2-yl]-2,4-dioxobutanoic Acid
J. Biol. Chem. 2003 278: 2777-2780. First Published on December 11, 2002; doi:10.1074/jbc.C200621200 [Abstract] [Full Text] [PDF]  


DNA: Replication Repair and Recombination:

Sinéad M. Kerins, Ruairi Collins, and Tommie V. McCarthy
Characterization of an Endonuclease IV 3'-5' Exonuclease Activity
J. Biol. Chem. 2003 278: 3048-3054. First Published on November 19, 2002; doi:10.1074/jbc.M210750200 [Abstract] [Full Text] [PDF]  

Faoud T. Ishmael, Michael A. Trakselis, and Stephen J. Benkovic
Protein-Protein Interactions in the Bacteriophage T4 Replisome. THE LEADING STRAND HOLOENZYME IS PHYSICALLY LINKED TO THE LAGGING STRAND HOLOENZYME AND THE PRIMOSOME
J. Biol. Chem. 2003 278: 3145-3152. First Published on November 9, 2002; doi:10.1074/jbc.M209858200 [Abstract] [Full Text] [PDF]  

Margaret A. Macris and Peter M. Glazer
Transcription Dependence of Chromosomal Gene Targeting by Triplex-forming Oligonucleotides
J. Biol. Chem. 2003 278: 3357-3362. First Published on November 12, 2002; doi:10.1074/jbc.M206542200 [Abstract] [Full Text] [PDF]  


Genes: Structure and Regulation:

Iaroslav Kuzmine, Philip A. Gottlieb, and Craig T. Martin
Binding of the Priming Nucleotide in the Initiation of Transcription by T7 RNA Polymerase
J. Biol. Chem. 2003 278: 2819-2823. First Published on November 9, 2002; doi:10.1074/jbc.M208405200 [Abstract] [Full Text] [PDF]  

Keith M. Giles, John M. Daly, Dianne J. Beveridge, Andrew M. Thomson, Dominic C. Voon, Henry M. Furneaux, Jalal A. Jazayeri, and Peter J. Leedman
The 3'-Untranslated Region of p21WAF1 mRNA Is a Composite cis-Acting Sequence Bound by RNA-binding Proteins from Breast Cancer Cells, Including HuR and Poly(C)-binding Protein
J. Biol. Chem. 2003 278: 2937-2946. First Published on November 12, 2002; doi:10.1074/jbc.M208439200 [Abstract] [Full Text] [PDF]  

Verena Strieder and Werner Lutz
E2F Proteins Regulate MYCN Expression in Neuroblastomas
J. Biol. Chem. 2003 278: 2983-2989. First Published on November 15, 2002; doi:10.1074/jbc.M207596200 [Abstract] [Full Text] [PDF]  

Benjamin Barré, Sylvie Avril, and Olivier Coqueret
Opposite Regulation of Myc and p21waf1 Transcription by STAT3 Proteins
J. Biol. Chem. 2003 278: 2990-2996. First Published on November 15, 2002; doi:10.1074/jbc.M210422200 [Abstract] [Full Text] [PDF]  

Hong Chen, Shinichi Toyooka, Adi F. Gazdar, and Jer-Tsong Hsieh
Epigenetic Regulation of a Novel Tumor Suppressor Gene (hDAB2IP) in Prostate Cancer Cell Lines
J. Biol. Chem. 2003 278: 3121-3130. First Published on November 21, 2002; doi:10.1074/jbc.M208230200 [Abstract] [Full Text] [PDF] Supplemental Data  

Brett L. Gourley, Samuel B. Parker, Barbara J. Jones, Kimberly B. Zumbrennen, and Elizabeth A. Leibold
Cytosolic Aconitase and Ferritin Are Regulated by Iron in Caenorhabditis elegans
J. Biol. Chem. 2003 278: 3227-3234. First Published on November 15, 2002; doi:10.1074/jbc.M210333200 [Abstract] [Full Text] [PDF]  

Tina Di Palma, Roberto Nitsch, Anna Mascia, Lucio Nitsch, Roberto Di Lauro, and Mariastella Zannini
The Paired Domain-containing Factor Pax8 and the Homeodomain-containing Factor TTF-1 Directly Interact and Synergistically Activate Transcription
J. Biol. Chem. 2003 278: 3395-3402. First Published on November 18, 2002; doi:10.1074/jbc.M205977200 [Abstract] [Full Text] [PDF]  

Siva R. Wigneshweraraj, Konstantin Kuznedelov, Konstantin Severinov, and Martin Buck
Multiple Roles of the RNA Polymerase beta Subunit Flap Domain in sigma 54-Dependent Transcription
J. Biol. Chem. 2003 278: 3455-3465. First Published on November 6, 2002; doi:10.1074/jbc.M209442200 [Abstract] [Full Text] [PDF]  

Gila Idelman, Tova Glaser, Charles T. Roberts, Jr., and Haim Werner
WT1-p53 Interactions in Insulin-like Growth Factor-I Receptor Gene Regulation
J. Biol. Chem. 2003 278: 3474-3482. First Published on November 19, 2002; doi:10.1074/jbc.M211606200 [Abstract] [Full Text] [PDF]  


RNA: Structure Metabolism and Catalysis:

Angeles Ortega, Martina Niksic, Angela Bachi, Matthias Wilm, Lucas Sánchez, Nicholas Hastie, and Juan Valcárcel
Biochemical Function of Female-Lethal (2)D/Wilms' Tumor Suppressor-1-associated Proteins in Alternative Pre-mRNA Splicing
J. Biol. Chem. 2003 278: 3040-3047. First Published on November 19, 2002; doi:10.1074/jbc.M210737200 [Abstract] [Full Text] [PDF]  


Protein Synthesis Post-Translation Modification and Degradation:

Yann Percherancier, Bernard Lagane, Thierry Planchenault, Isabelle Staropoli, Ralf Altmeyer, Jean-Louis Virelizier, Fernando Arenzana-Seisdedos, Daniel C. Hoessli, and Françoise Bachelerie
HIV-1 Entry into T-cells Is Not Dependent on CD4 and CCR5 Localization to Sphingolipid-enriched, Detergent-resistant, Raft Membrane Domains
J. Biol. Chem. 2003 278: 3153-3161. First Published on November 12, 2002; doi:10.1074/jbc.M207371200 [Abstract] [Full Text] [PDF]  

John Dresios, Panagiotis Panopoulos, Katsuyuki Suzuki, and Dennis Synetos
A Dispensable Yeast Ribosomal Protein Optimizes Peptidyltransferase Activity and Affects Translocation
J. Biol. Chem. 2003 278: 3314-3322. First Published on November 13, 2002; doi:10.1074/jbc.M207533200 [Abstract] [Full Text] [PDF]  

Gregory J. Babcock, Michael Farzan, and Joseph Sodroski
Ligand-independent Dimerization of CXCR4, a Principal HIV-1 Coreceptor
J. Biol. Chem. 2003 278: 3378-3385. First Published on November 13, 2002; doi:10.1074/jbc.M210140200 [Abstract] [Full Text] [PDF]  


Genomics Proteomics and Bioinformatics:

Viktor M. Boer, Johannes H. de Winde, Jack T. Pronk, and Matthew D. W. Piper
The Genome-wide Transcriptional Responses of Saccharomyces cerevisiae Grown on Glucose in Aerobic Chemostat Cultures Limited for Carbon, Nitrogen, Phosphorus, or Sulfur
J. Biol. Chem. 2003 278: 3265-3274. First Published on October 31, 2002; doi:10.1074/jbc.M209759200 [Abstract] [Full Text] [PDF]  

Beena Pillai, Jiyoti Verma, Anju Abraham, Princy Francis, Yadunanda Kumar, Utpal Tatu, Samir K. Brahmachari, and Parag P. Sadhale
Whole Genome Expression Profiles of Yeast RNA Polymerase II Core Subunit, Rpb4, in Stress and Nonstress Conditions
J. Biol. Chem. 2003 278: 3339-3346. First Published on November 11, 2002; doi:10.1074/jbc.M112180200 [Abstract] [Full Text] [PDF] Supplemental Data  


Protein Structure and Folding:

Lisa A. Kueltzo, John Osiecki, Jeff Barker, Wendy L. Picking, Baran Ersoy, William D. Picking, and C. Russell Middaugh
Structure-Function Analysis of Invasion Plasmid Antigen C (IpaC) from Shigella flexneri
J. Biol. Chem. 2003 278: 2792-2798. First Published on November 8, 2002; doi:10.1074/jbc.M208383200 [Abstract] [Full Text] [PDF]  

Takashi Inui, Tadayasu Ohkubo, Maiko Emi, Daisuke Irikura, Osamu Hayaishi, and Yoshihiro Urade
Characterization of the Unfolding Process of Lipocalin-type Prostaglandin D Synthase
J. Biol. Chem. 2003 278: 2845-2852. First Published on November 18, 2002; doi:10.1074/jbc.M209934200 [Abstract] [Full Text] [PDF]  

Miya Kamihira, Yuki Oshiro, Satoru Tuzi, Atsuko Y. Nosaka, Hazime Saitô, and Akira Naito
Effect of Electrostatic Interaction on Fibril Formation of Human Calcitonin as Studied by High Resolution Solid State 13C NMR
J. Biol. Chem. 2003 278: 2859-2865. First Published on November 21, 2002; doi:10.1074/jbc.M205285200 [Abstract] [Full Text] [PDF]  

Cyril C. Curtain, Fedá E. Ali, Danielle G. Smith, Ashley I. Bush, Colin L. Masters, and Kevin J. Barnham
Metal Ions, pH, and Cholesterol Regulate the Interactions of Alzheimer's Disease Amyloid-beta Peptide with Membrane Lipid
J. Biol. Chem. 2003 278: 2977-2982. First Published on November 14, 2002; doi:10.1074/jbc.M205455200 [Abstract] [Full Text] [PDF]  

Masatoshi Nukui, Kenneth B. Taylor, David T. McPherson, Mark K. Shigenaga, and Mark J. Jedrzejas
The Function of Hydrophobic Residues in the Catalytic Cleft of Streptococcus pneumoniae Hyaluronate Lyase. KINETIC CHARACTERIZATION OF MUTANT ENZYME FORMS
J. Biol. Chem. 2003 278: 3079-3088. First Published on November 21, 2002; doi:10.1074/jbc.M204999200 [Abstract] [Full Text] [PDF]  

Ozgur Ogut, M. Moazzem Hossain, and Jian-Ping Jin
Interactions between Nebulin-like Motifs and Thin Filament Regulatory Proteins
J. Biol. Chem. 2003 278: 3089-3097. First Published on November 21, 2002; doi:10.1074/jbc.M205853200 [Abstract] [Full Text] [PDF]  

Dirk Schneider and Donald M. Engelman
GALLEX, a Measurement of Heterologous Association of Transmembrane Helices in a Biological Membrane
J. Biol. Chem. 2003 278: 3105-3111. First Published on November 21, 2002; doi:10.1074/jbc.M206287200 [Abstract] [Full Text] [PDF]  

Rym Barbouche, Raymond Miquelis, Ian M. Jones, and Emmanuel Fenouillet
Protein-disulfide Isomerase-mediated Reduction of Two Disulfide Bonds of HIV Envelope Glycoprotein 120 Occurs Post-CXCR4 Binding and Is Required for Fusion
J. Biol. Chem. 2003 278: 3131-3136. First Published on September 5, 2002; doi:10.1074/jbc.M205467200 [Abstract] [Full Text] [PDF]  

Stefano Mangani, Wolfram Meyer-Klaucke, Arthur J. G. Moir, Maria Ranieri-Raggi, Daniela Martini, and Antonio Raggi
Characterization of the Zinc-binding Site of the Histidine-Proline-rich Glycoprotein Associated with Rabbit Skeletal Muscle AMP Deaminase
J. Biol. Chem. 2003 278: 3176-3184. First Published on November 18, 2002; doi:10.1074/jbc.M208794200 [Abstract] [Full Text] [PDF]  

Thomas Antony, Wolfgang Hoyer, Dmitry Cherny, Gudrun Heim, Thomas M. Jovin, and Vinod Subramaniam
Cellular Polyamines Promote the Aggregation of alpha -Synuclein
J. Biol. Chem. 2003 278: 3235-3240. First Published on November 14, 2002; doi:10.1074/jbc.M208249200 [Abstract] [Full Text] [PDF]  

Hiroaki Nakano, Takuya Yoshida, Susumu Uchiyama, Masako Kawachi, Hitomi Matsuo, Takayuki Kato, Atsushi Ohshima, Yoshiharu Yamaichi, Takeshi Honda, Hiroaki Kato, Yuriko Yamagata, Tadayasu Ohkubo, and Yuji Kobayashi
Structure and Binding Mode of a Ribosome Recycling Factor (RRF) from Mesophilic Bacterium
J. Biol. Chem. 2003 278: 3427-3436. First Published on October 30, 2002; doi:10.1074/jbc.M208098200 [Abstract] [Full Text] [PDF] Supplemental Data  

Isabelle Sponne, Alexandre Fifre, Béatrice Drouet, Christophe Klein, Violette Koziel, Martine Pinçon-Raymond, Jean-Luc Olivier, Jean Chambaz, and Thierry Pillot
Apoptotic Neuronal Cell Death Induced by the Non-fibrillar Amyloid-beta Peptide Proceeds through an Early Reactive Oxygen Species-dependent Cytoskeleton Perturbation
J. Biol. Chem. 2003 278: 3437-3445. First Published on November 14, 2002; doi:10.1074/jbc.M206745200 [Abstract] [Full Text] [PDF]  


Enzyme Catalysis and Regulation:

Christian Lindermayr, Judith Fliegmann, and Jürgen Ebel
Deletion of a Single Amino Acid Residue from Different 4-Coumarate:CoA Ligases from Soybean Results in the Generation of New Substrate Specificities
J. Biol. Chem. 2003 278: 2781-2786. First Published on November 5, 2002; doi:10.1074/jbc.M202632200 [Abstract] [Full Text] [PDF]  

Amit V. Pandey, Synthia H. Mellon, and Walter L. Miller
Protein Phosphatase 2A and Phosphoprotein SET Regulate Androgen Production by P450c17
J. Biol. Chem. 2003 278: 2837-2844. First Published on November 19, 2002; doi:10.1074/jbc.M209527200 [Abstract] [Full Text] [PDF]  

Nadia Nour, Ajoy Basak, Michel Chrétien, and Nabil G. Seidah
Structure-Function Analysis of the Prosegment of the Proprotein Convertase PC5A
J. Biol. Chem. 2003 278: 2886-2895. First Published on October 31, 2002; doi:10.1074/jbc.M208009200 [Abstract] [Full Text] [PDF]  

Changjian Feng, Heather L. Wilson, John K. Hurley, James T. Hazzard, Gordon Tollin, K. V. Rajagopalan, and John H. Enemark
Role of Conserved Tyrosine 343 in Intramolecular Electron Transfer in Human Sulfite Oxidase
J. Biol. Chem. 2003 278: 2913-2920. First Published on November 6, 2002; doi:10.1074/jbc.M210374200 [Abstract] [Full Text] [PDF]  

Yeming Wang and Hwai-Chen Guo
Two-step Dimerization for Autoproteolysis to Activate Glycosylasparaginase
J. Biol. Chem. 2003 278: 3210-3219. First Published on November 13, 2002; doi:10.1074/jbc.M210431200 [Abstract] [Full Text] [PDF]  

Vikash J. Bhagwandin, Leola W.-T. Hau, Jon Mallen-St. Clair, Paul J. Wolters, and George H. Caughey
Structure and Activity of Human Pancreasin, a Novel Tryptic Serine Peptidase Expressed Primarily by the Pancreas
J. Biol. Chem. 2003 278: 3363-3371. First Published on November 18, 2002; doi:10.1074/jbc.M209353200 [Abstract] [Full Text] [PDF]  

Markus Knipp, Oliver Braun, Peter M. Gehrig, Ragna Sack, and Milan Vasák
Zn(II)-free Dimethylargininase-1 (DDAH-1) Is Inhibited upon Specific Cys-S-Nitrosylation
J. Biol. Chem. 2003 278: 3410-3416. First Published on November 18, 2002; doi:10.1074/jbc.M209088200 [Abstract] [Full Text] [PDF]  


Metabolism and Bioenergetics:

Changhong Li, Habiba Najafi, Yevgeny Daikhin, Ilana B. Nissim, Heather W. Collins, Marc Yudkoff, Franz M. Matschinsky, and Charles A. Stanley
Regulation of Leucine-stimulated Insulin Secretion and Glutamine Metabolism in Isolated Rat Islets
J. Biol. Chem. 2003 278: 2853-2858. First Published on November 19, 2002; doi:10.1074/jbc.M210577200 [Abstract] [Full Text] [PDF]  

D. Ross Laybutt, Mariela Glandt, Gang Xu, Yu Bai Ahn, Nitin Trivedi, Susan Bonner-Weir, and Gordon C. Weir
Critical Reduction in beta -Cell Mass Results in Two Distinct Outcomes over Time. ADAPTATION WITH IMPAIRED GLUCOSE TOLERANCE OR DECOMPENSATED DIABETES
J. Biol. Chem. 2003 278: 2997-3005. First Published on November 15, 2002; doi:10.1074/jbc.M210581200 [Abstract] [Full Text] [PDF]  

Dirk Flemming, Petra Hellwig, and Thorsten Friedrich
Involvement of Tyrosines 114 and 139 of Subunit NuoB in the Proton Pathway around Cluster N2 in Escherichia coli NADH:Ubiquinone Oxidoreductase
J. Biol. Chem. 2003 278: 3055-3062. First Published on November 20, 2002; doi:10.1074/jbc.M208849200 [Abstract] [Full Text] [PDF]  

Frank Petrat, Stanislaw Pindiur, Michael Kirsch, and Herbert de Groot
NAD(P)H, a Primary Target of 1O2 in Mitochondria of Intact Cells
J. Biol. Chem. 2003 278: 3298-3307. First Published on November 13, 2002; doi:10.1074/jbc.M204230200 [Abstract] [Full Text] [PDF]  


Glycobiology and Extracellular Matrices:

Rajamani Lakshminarayanan, Suresh Valiyaveettil, Veena S. Rao, and R. Manjunatha Kini
Purification, Characterization, and in Vitro Mineralization Studies of a Novel Goose Eggshell Matrix Protein, Ansocalcin
J. Biol. Chem. 2003 278: 2928-2936. First Published on November 12, 2002; doi:10.1074/jbc.M201518200 [Abstract] [Full Text] [PDF]  

Takashi Sato, Masanori Gotoh, Katsue Kiyohara, Tomohiro Akashima, Hiroko Iwasaki, Akihiko Kameyama, Hideo Mochizuki, Toshikazu Yada, Niro Inaba, Akira Togayachi, Takashi Kudo, Masahiro Asada, Hideto Watanabe, Toru Imamura, Koji Kimata, and Hisashi Narimatsu
Differential Roles of Two N-Acetylgalactosaminyltransferases, CSGalNAcT-1, and a Novel Enzyme, CSGalNAcT-2. INITIATION AND ELONGATION IN SYNTHESIS OF CHONDROITIN SULFATE
J. Biol. Chem. 2003 278: 3063-3071. First Published on November 20, 2002; doi:10.1074/jbc.M208886200 [Abstract] [Full Text] [PDF]  

Toru Uyama, Hiroshi Kitagawa, Junko Tanaka, Jun-ichi Tamura, Tomoya Ogawa, and Kazuyuki Sugahara
Molecular Cloning and Expression of a Second Chondroitin N-Acetylgalactosaminyltransferase Involved in the Initiation and Elongation of Chondroitin/Dermatan Sulfate
J. Biol. Chem. 2003 278: 3072-3078. First Published on November 13, 2002; doi:10.1074/jbc.M209446200 [Abstract] [Full Text] [PDF]  

Yukinao Shibukawa, Motoko Takahashi, Isabelle Laffont, Koichi Honke, and Naoyuki Taniguchi
Down-regulation of Hydrogen Peroxide-induced PKCdelta Activation in N-Acetylglucosaminyltransferase III-transfected HeLaS3 Cells
J. Biol. Chem. 2003 278: 3197-3203. First Published on November 8, 2002; doi:10.1074/jbc.M207870200 [Abstract] [Full Text] [PDF]  

Sebastian Franken, Ulrich Junghans, Volker Rosslenbroich, Stephan L. Baader, Ralf Hoffmann, Volkmar Gieselmann, Christoph Viebahn, and Joachim Kappler
Collapsin Response Mediator Proteins of Neonatal Rat Brain Interact with Chondroitin Sulfate
J. Biol. Chem. 2003 278: 3241-3250. First Published on November 19, 2002; doi:10.1074/jbc.M210181200 [Abstract] [Full Text] [PDF]  

Magnus S. Alphey, Helen Attrill, Paul R. Crocker, and Daan M. F. van Aalten
High Resolution Crystal Structures of Siglec-7. INSIGHTS INTO LIGAND SPECIFICITY IN THE SIGLEC FAMILY
J. Biol. Chem. 2003 278: 3372-3377. First Published on November 15, 2002; doi:10.1074/jbc.M210602200 [Abstract] [Full Text] [PDF]  

Amantha Thathiah, Carl P. Blobel, and Daniel D. Carson
Tumor Necrosis Factor-alpha Converting Enzyme/ADAM 17 Mediates MUC1 Shedding
J. Biol. Chem. 2003 278: 3386-3394. First Published on November 18, 2002; doi:10.1074/jbc.M208326200 [Abstract] [Full Text] [PDF]  

Toyohide Shinkawa, Kazuyasu Nakamura, Naoko Yamane, Emi Shoji-Hosaka, Yutaka Kanda, Mikiko Sakurada, Kazuhisa Uchida, Hideharu Anazawa, Mitsuo Satoh, Motoo Yamasaki, Nobuo Hanai, and Kenya Shitara
The Absence of Fucose but Not the Presence of Galactose or Bisecting N-Acetylglucosamine of Human IgG1 Complex-type Oligosaccharides Shows the Critical Role of Enhancing Antibody-dependent Cellular Cytotoxicity
J. Biol. Chem. 2003 278: 3466-3473. First Published on November 8, 2002; doi:10.1074/jbc.M210665200 [Abstract] [Full Text] [PDF]  


Lipids and Lipoproteins:

Ankang Li, Murali Sadasivam, and Jeak Ling Ding
Receptor-Ligand Interaction between Vitellogenin Receptor (VtgR) and Vitellogenin (Vtg), Implications on Low Density Lipoprotein Receptor and Apolipoprotein B/E. THE FIRST THREE LIGAND-BINDING REPEATS OF VTGR INTERACT WITH THE AMINO-TERMINAL REGION OF VTG
J. Biol. Chem. 2003 278: 2799-2806. First Published on November 11, 2002; doi:10.1074/jbc.M205067200 [Abstract] [Full Text] [PDF]  

David J. Shields, Richard Lehner, Luis B. Agellon, and Dennis E. Vance
Membrane Topography of Human Phosphatidylethanolamine N-Methyltransferase
J. Biol. Chem. 2003 278: 2956-2962. First Published on November 12, 2002; doi:10.1074/jbc.M210904200 [Abstract] [Full Text] [PDF]  


Membrane Transport Structure Function and Biogenesis:

Radhika Ganeshan, Anke Di, Deborah J. Nelson, Michael W. Quick, and Kevin L. Kirk
The Interaction between Syntaxin 1A and Cystic Fibrosis Transmembrane Conductance Regulator Cl- Channels Is Mechanistically Distinct from Syntaxin 1A-SNARE Interactions
J. Biol. Chem. 2003 278: 2876-2885. First Published on November 22, 2002; doi:10.1074/jbc.M211790200 [Abstract] [Full Text] [PDF]  

Quansheng Zhu, Diana W. K. Lee, and Joseph R. Casey
Novel Topology in C-terminal Region of the Human Plasma Membrane Anion Exchanger, AE1
J. Biol. Chem. 2003 278: 3112-3120. First Published on November 21, 2002; doi:10.1074/jbc.M207797200 [Abstract] [Full Text] [PDF]  

Annette Nicke, Marion L. Loughnan, Emma L. Millard, Paul F. Alewood, David J. Adams, Norelle L. Daly, David J. Craik, and Richard J. Lewis
Isolation, Structure, and Activity of GID, a Novel alpha 4/7-Conotoxin with an Extended N-terminal Sequence
J. Biol. Chem. 2003 278: 3137-3144. First Published on November 4, 2002; doi:10.1074/jbc.M210280200 [Abstract] [Full Text] [PDF]  

Asami Makino, Takeshi Baba, Kazushi Fujimoto, Kunihiko Iwamoto, Yoshiaki Yano, Nobuo Terada, Shinichi Ohno, Satoshi B. Sato, Akinori Ohta, Masato Umeda, Katsumi Matsuzaki, and Toshihide Kobayashi
Cinnamycin (Ro 09-0198) Promotes Cell Binding and Toxicity by Inducing Transbilayer Lipid Movement
J. Biol. Chem. 2003 278: 3204-3209. First Published on November 22, 2002; doi:10.1074/jbc.M210347200 [Abstract] [Full Text] [PDF]  

Mitsunori Fukuda, Eiko Kanno, Yukie Ogata, Chika Saegusa, Taeyoon Kim, Y. Peng Loh, and Akitsugu Yamamoto
Nerve Growth Factor-dependent Sorting of Synaptotagmin IV Protein to Mature Dense-core Vesicles That Undergo Calcium-dependent Exocytosis in PC12 Cells
J. Biol. Chem. 2003 278: 3220-3226. First Published on November 21, 2002; doi:10.1074/jbc.M208323200 [Abstract] [Full Text] [PDF]  

Dong Wook Shin, Zui Pan, Eun Kyung Kim, Jae Man Lee, Manjunatha B. Bhat, Jerome Parness, Do Han Kim, and Jianjie Ma
A Retrograde Signal from Calsequestrin for the Regulation of Store-operated Ca2+ Entry in Skeletal Muscle
J. Biol. Chem. 2003 278: 3286-3292. First Published on November 4, 2002; doi:10.1074/jbc.M209045200 [Abstract] [Full Text] [PDF]  

Liliana Manciu, Xiu-Bao Chang, Frédéric Buyse, Yue-Xian Hou, Adelin Gustot, John R. Riordan, and Jean Marie Ruysschaert
Intermediate Structural States Involved in MRP1-mediated Drug Transport. ROLE OF GLUTATHIONE
J. Biol. Chem. 2003 278: 3347-3356. First Published on November 6, 2002; doi:10.1074/jbc.M207963200 [Abstract] [Full Text] [PDF]  

Dongming Cai, Jae Yoon Leem, Jeffrey P. Greenfield, Pei Wang, Benny S. Kim, Runsheng Wang, Kryslaine O. Lopes, Seong-Hun Kim, Hui Zheng, Paul Greengard, Sangram S. Sisodia, Gopal Thinakaran, and Huaxi Xu
Presenilin-1 Regulates Intracellular Trafficking and Cell Surface Delivery of beta -Amyloid Precursor Protein
J. Biol. Chem. 2003 278: 3446-3454. First Published on November 14, 2002; doi:10.1074/jbc.M209065200 [Abstract] [Full Text] [PDF]  

Monica Yabal, Silvia Brambillasca, Paolo Soffientini, Emanuela Pedrazzini, Nica Borgese, and Marja Makarow
Translocation of the C Terminus of a Tail-anchored Protein across the Endoplasmic Reticulum Membrane in Yeast Mutants Defective in Signal Peptide-driven Translocation
J. Biol. Chem. 2003 278: 3489-3496. First Published on November 22, 2002; doi:10.1074/jbc.M210253200 [Abstract] [Full Text] [PDF]  


Mechanisms Of Signal Transduction:

Anders Woetmann, Johannes Brockdorff, Paola Lovato, Mette Nielsen, Vagn Leick, Klaus Rieneck, Arne Svejgaard, Carsten Geisler, and Niels Ødum
Protein Phosphatase 2A (PP2A) Regulates Interleukin-4-mediated STAT6 Signaling
J. Biol. Chem. 2003 278: 2787-2791. First Published on November 7, 2002; doi:10.1074/jbc.M210196200 [Abstract] [Full Text] [PDF]  

Jeffrey C. Chen, Shunhui Zhuang, Tony H. Nguyen, Gerry R. Boss, and Renate B. Pilz
Oncogenic Ras Leads to Rho Activation by Activating the Mitogen-activated Protein Kinase Pathway and Decreasing Rho-GTPase-activating Protein Activity
J. Biol. Chem. 2003 278: 2807-2818. First Published on November 11, 2002; doi:10.1074/jbc.M207943200 [Abstract] [Full Text] [PDF]  

Mingqi Tan, Xuemin Xu, Motoi Ohba, Wataru Ogawa, and Mei-Zhen Cui
Thrombin Rapidly Induces Protein Kinase D Phosphorylation, and Protein Kinase C delta Mediates the Activation
J. Biol. Chem. 2003 278: 2824-2828. First Published on November 12, 2002; doi:10.1074/jbc.M211523200 [Abstract] [Full Text] [PDF]  

Sricharan Bandhakavi, Richard O. McCann, David E. Hanna, and Claiborne V. C. Glover
A Positive Feedback Loop between Protein Kinase CKII and Cdc37 Promotes the Activity of Multiple Protein Kinases
J. Biol. Chem. 2003 278: 2829-2836. First Published on November 14, 2002; doi:10.1074/jbc.M206662200 [Abstract] [Full Text] [PDF]  

Bukhtiar H. Shah, Jae-Won Soh, and Kevin J. Catt
Dependence of Gonadotropin-releasing Hormone-induced Neuronal MAPK Signaling on Epidermal Growth Factor Receptor Transactivation
J. Biol. Chem. 2003 278: 2866-2875. First Published on November 21, 2002; doi:10.1074/jbc.M208783200 [Abstract] [Full Text] [PDF]  

Yong Hee Lee, Jodel Giraud, Roger J. Davis, and Morris F. White
c-Jun N-terminal Kinase (JNK) Mediates Feedback Inhibition of the Insulin Signaling Cascade
J. Biol. Chem. 2003 278: 2896-2902. First Published on November 1, 2002; doi:10.1074/jbc.M208359200 [Abstract] [Full Text] [PDF]  

Florence Legendre, Jayesh Dudhia, Jean-Pierre Pujol, and Patrick Bogdanowicz
JAK/STAT but Not ERK1/ERK2 Pathway Mediates Interleukin (IL)-6/Soluble IL-6R Down-regulation of Type II Collagen, Aggrecan Core, and Link Protein Transcription in Articular Chondrocytes. ASSOCIATION WITH A DOWN-REGULATION OF SOX9 EXPRESSION
J. Biol. Chem. 2003 278: 2903-2912. First Published on November 4, 2002; doi:10.1074/jbc.M110773200 [Abstract] [Full Text] [PDF]  

Hironori Ogawa, Ayako Murayama, Shigekazu Nagata, and Rikiro Fukunaga
Regulation of Myeloid Zinc Finger Protein 2A Transactivation Activity through Phosphorylation by Mitogen-activated Protein Kinases
J. Biol. Chem. 2003 278: 2921-2927. First Published on November 8, 2002; doi:10.1074/jbc.M207615200 [Abstract] [Full Text] [PDF]  

Olivia Crociani, Leonardo Guasti, Manuela Balzi, Andrea Becchetti, Enzo Wanke, Massimo Olivotto, Randy S. Wymore, and Annarosa Arcangeli
Cell Cycle-dependent Expression of HERG1 and HERG1B Isoforms in Tumor Cells
J. Biol. Chem. 2003 278: 2947-2955. First Published on November 12, 2002; doi:10.1074/jbc.M210789200 [Abstract] [Full Text] [PDF]  

Patricia C. Cogswell, David F. Kashatus, Jayne A. Keifer, Denis C. Guttridge, Julie Y. Reuther, Cindy Bristow, Sophie Roy, Donald W. Nicholson, and Albert S. Baldwin, Jr.
NF-kappa B and Ikappa Balpha Are Found in the Mitochondria. EVIDENCE FOR REGULATION OF MITOCHONDRIAL GENE EXPRESSION BY NF-kappa B
J. Biol. Chem. 2003 278: 2963-2968. First Published on November 13, 2002; doi:10.1074/jbc.M209995200 [Abstract] [Full Text] [PDF]  

Janet L. Martin, Sarah M. Weenink, and Robert C. Baxter
Insulin-like Growth Factor-binding Protein-3 Potentiates Epidermal Growth Factor Action in MCF-10A Mammary Epithelial Cells. INVOLVEMENT OF p44/42 AND p38 MITOGEN-ACTIVATED PROTEIN KINASES
J. Biol. Chem. 2003 278: 2969-2976. First Published on November 13, 2002; doi:10.1074/jbc.M210739200 [Abstract] [Full Text] [PDF]  

Daria Illenberger, Claudia Walliser, Bernd Nürnberg, Maria Diaz Lorente, and Peter Gierschik
Specificity and Structural Requirements of Phospholipase C-beta Stimulation by Rho GTPases Versus G Protein beta gamma Dimers
J. Biol. Chem. 2003 278: 3006-3014. First Published on November 18, 2002; doi:10.1074/jbc.M208282200 [Abstract] [Full Text] [PDF]  

Shunan Li, Tasaburo Takasu, David M. Perlman, Mark S. Peterson, David Burrichter, Svetlana Avdulov, Peter B. Bitterman, and Vitaly A. Polunovsky
Translation Factor eIF4E Rescues Cells from Myc-dependent Apoptosis by Inhibiting Cytochrome c Release
J. Biol. Chem. 2003 278: 3015-3022. First Published on November 18, 2002; doi:10.1074/jbc.M208821200 [Abstract] [Full Text] [PDF]  

Tomoshige Kino and George P. Chrousos
Tumor Necrosis Factor alpha Receptor- and Fas-associated FLASH Inhibit Transcriptional Activity of the Glucocorticoid Receptor by Binding to and Interfering with Its Interaction with p160 Type Nuclear Receptor Coactivators
J. Biol. Chem. 2003 278: 3023-3029. First Published on December 10, 2002; doi:10.1074/jbc.M209234200 [Abstract] [Full Text] [PDF]  

Jens Henrik Norum, Kent Hart, and Finn Olav Levy
Ras-dependent ERK Activation by the Human Gs-coupled Serotonin Receptors 5-HT4(b) and 5-HT7(a)
J. Biol. Chem. 2003 278: 3098-3104. First Published on November 21, 2002; doi:10.1074/jbc.M206237200 [Abstract] [Full Text] [PDF]  

Martin Heck, Sandra A. Schädel, Dieter Maretzki, Franz J. Bartl, Eglof Ritter, Krzysztof Palczewski, and Klaus Peter Hofmann
Signaling States of Rhodopsin. FORMATION OF THE STORAGE FORM, METARHODOPSIN III, FROM ACTIVE METARHODOPSIN II
J. Biol. Chem. 2003 278: 3162-3169. First Published on November 9, 2002; doi:10.1074/jbc.M209675200 [Abstract] [Full Text] [PDF]  

Ken-ichi Setsukinai, Yasuteru Urano, Katsuko Kakinuma, Hideyuki J. Majima, and Tetsuo Nagano
Development of Novel Fluorescence Probes That Can Reliably Detect Reactive Oxygen Species and Distinguish Specific Species
J. Biol. Chem. 2003 278: 3170-3175. First Published on November 4, 2002; doi:10.1074/jbc.M209264200 [Abstract] [Full Text] [PDF] Supplemental Data  

Kendall D. Carey, Robert T. Watson, Jeffrey E. Pessin, and Philip J. S. Stork
The Requirement of Specific Membrane Domains for Raf-1 Phosphorylation and Activation
J. Biol. Chem. 2003 278: 3185-3196. First Published on November 21, 2002; doi:10.1074/jbc.M207014200 [Abstract] [Full Text] [PDF]  

Francisco J. Nicolás, Kerstin Lehmann, Patricia H. Warne, Caroline S. Hill, and Julian Downward
Epithelial to Mesenchymal Transition in Madin-Darby Canine Kidney Cells Is Accompanied by Down-regulation of Smad3 Expression, Leading to Resistance to Transforming Growth Factor-beta -induced Growth Arrest
J. Biol. Chem. 2003 278: 3251-3256. First Published on November 14, 2002; doi:10.1074/jbc.M209019200 [Abstract] [Full Text] [PDF]  

Marie-Agnès Doucey, Laurence Goffin, Dieter Naeher, Olivier Michielin, Petra Baumgärtner, Philippe Guillaume, Ed Palmer, and Immanuel F. Luescher
CD3delta Establishes a Functional Link between the T Cell Receptor and CD8
J. Biol. Chem. 2003 278: 3257-3264. First Published on September 4, 2002; doi:10.1074/jbc.M208119200 [Abstract] [Full Text] [PDF]  

Nancy Dumont, Andrei V. Bakin, and Carlos L. Arteaga
Autocrine Transforming Growth Factor-beta Signaling Mediates Smad-independent Motility in Human Cancer Cells
J. Biol. Chem. 2003 278: 3275-3285. First Published on November 5, 2002; doi:10.1074/jbc.M204623200 [Abstract] [Full Text] [PDF]  

Arthur Christopoulos, George Christopoulos, Maria Morfis, Madhara Udawela, Marc Laburthe, Alain Couvineau, Kenji Kuwasako, Nanda Tilakaratne, and Patrick M. Sexton
Novel Receptor Partners and Function of Receptor Activity-modifying Proteins
J. Biol. Chem. 2003 278: 3293-3297. First Published on November 21, 2002; doi:10.1074/jbc.C200629200 [Abstract] [Full Text] [PDF]  

Changsoo Chang, Eugenia Magracheva, Serguei Kozlov, Steven Fong, Gregory Tobin, Sergei Kotenko, Alexander Wlodawer, and Alexander Zdanov
Crystal Structure of Interleukin-19 Defines a New Subfamily of Helical Cytokines
J. Biol. Chem. 2003 278: 3308-3313. First Published on October 25, 2002; doi:10.1074/jbc.M208602200 [Abstract] [Full Text] [PDF]  

Frederic D. Sigoillot, J. Andrew Berkowski, Severine M. Sigoillot, Damian H. Kotsis, and Hedeel I. Guy
Cell Cycle-dependent Regulation of Pyrimidine Biosynthesis
J. Biol. Chem. 2003 278: 3403-3409. First Published on November 15, 2002; doi:10.1074/jbc.M211078200 [Abstract] [Full Text] [PDF]  

Roy R. Hantgan, Douglas S. Lyles, T. Conn Mallett, Mattia Rocco, Chandrasekaran Nagaswami, and John W. Weisel
Ligand Binding Promotes the Entropy-driven Oligomerization of Integrin alpha IIbbeta 3
J. Biol. Chem. 2003 278: 3417-3426. First Published on November 7, 2002; doi:10.1074/jbc.M208869200 [Abstract] [Full Text] [PDF]  


Molecular Basis Of Cell and Developmental Biology:

Carlos Ribeiro, Michel Vignes, and Michel Brehélin
Xenorhabdus nematophila (Enterobacteriacea) Secretes a Cation-selective Calcium-independent Porin Which Causes Vacuolation of the Rough Endoplasmic Reticulum and Cell Lysis
J. Biol. Chem. 2003 278: 3030-3039. First Published on November 18, 2002; doi:10.1074/jbc.M210353200 [Abstract] [Full Text] [PDF]  

Heidi Koegel, Susanne Kaesler, Ralf Burgstahler, Sabine Werner, and Christian Alzheimer
Unexpected Down-regulation of the hIK1 Ca2+-activated K+ Channel by Its Opener 1-Ethyl-2-benzimidazolinone in HaCaT Keratinocytes. INVERSE EFFECTS ON CELL GROWTH AND PROLIFERATION
J. Biol. Chem. 2003 278: 3323-3330. First Published on November 5, 2002; doi:10.1074/jbc.M208914200 [Abstract] [Full Text] [PDF]  

Shirley M. L. Tse, Wendy Furuya, Elizabeth Gold, Alan D. Schreiber, Kirsten Sandvig, Robert D. Inman, and Sergio Grinstein
Differential Role of Actin, Clathrin, and Dynamin in Fcgamma Receptor-mediated Endocytosis and Phagocytosis
J. Biol. Chem. 2003 278: 3331-3338. First Published on November 6, 2002; doi:10.1074/jbc.M207966200 [Abstract] [Full Text] [PDF]  

Peter J. Sheffield, Carey J. Oliver, Brandon E. Kremer, Sitong Sheng, Zhifeng Shao, and Ian G. Macara
Borg/Septin Interactions and the Assembly of Mammalian Septin Heterodimers, Trimers, and Filaments
J. Biol. Chem. 2003 278: 3483-3488. First Published on November 21, 2002; doi:10.1074/jbc.M209701200 [Abstract] [Full Text] [PDF]  


Additions and Corrections:

Chad R. Borges, Timothy J. Geddes, J. Throck Watson, and Donald M. Kuhn
Dopamine biosynthesis is regulated by S-glutathionylation. Potential mechanism of tyrosine hydroxylase inhibition under oxidative stress.
J. Biol. Chem. 2003 278: 3497. [Full Text] [PDF]  

Anna A. Noga, Yang Zhao, and Dennis E. Vance
An unexpected requirement for phosphatidylethanol- amine N-methyltransferase in the secretion of very low density lipoproteins.
J. Biol. Chem. 2003 278: 3498. [Full Text] [PDF]  


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