Minireviews:

Marco Conti, Wito Richter, Celine Mehats, Gabriel Livera, Jy-Young Park, and Catherine Jin

Cyclic AMP-specific PDE4 Phosphodiesterases as Critical Components of Cyclic AMP Signaling
J. Biol. Chem. 2003 278: 5493-5496. First Published on December 18, 2002; doi:10.1074/jbc.R200029200 [Full Text] [PDF]  

Accelerated Publications:

Kyoji Takekuni, Wataru Ikeda, Tsutomu Fujito, Koji Morimoto, Masakazu Takeuchi, Morito Monden, and Yoshimi Takai

Direct Binding of Cell Polarity Protein PAR-3 to Cell-Cell Adhesion Molecule Nectin at Neuroepithelial Cells of Developing Mouse
J. Biol. Chem. 2003 278: 5497-5500. First Published on January 5, 2003; doi:10.1074/jbc.C200707200 [Abstract] [Full Text] [PDF]  

Colin Rickman and Bazbek Davletov

Mechanism of Calcium-independent Synaptotagmin Binding to Target SNAREs
J. Biol. Chem. 2003 278: 5501-5504. First Published on December 20, 2002; doi:10.1074/jbc.C200692200 [Abstract] [Full Text] [PDF]  

Carole Gwizdek, Batool Ossareh-Nazari, Amy M. Brownawell, Alain Doglio, Edouard Bertrand, Ian G. Macara, and Catherine Dargemont

Exportin-5 Mediates Nuclear Export of Minihelix-containing RNAs
J. Biol. Chem. 2003 278: 5505-5508. First Published on December 30, 2002; doi:10.1074/jbc.C200668200 [Abstract] [Full Text] [PDF]  

Naohiro Inohara, Yasunori Ogura, Ana Fontalba, Olga Gutierrez, Fernando Pons, Javier Crespo, Koichi Fukase, Seiichi Inamura, Shoichi Kusumoto, Masahito Hashimoto, Simon J. Foster, Anthony P. Moran, Jose L. Fernandez-Luna, and Gabriel Nuñez

Host Recognition of Bacterial Muramyl Dipeptide Mediated through NOD2. IMPLICATIONS FOR CROHN'S DISEASE
J. Biol. Chem. 2003 278: 5509-5512. First Published on January 4, 2003; doi:10.1074/jbc.C200673200 [Abstract] [Full Text] [PDF]  

Norihiro Maeda, Jérôme Nigou, Jean-Louis Herrmann, Mary Jackson, Ali Amara, Philippe Henri Lagrange, Germain Puzo, Brigitte Gicquel, and Olivier Neyrolles

The Cell Surface Receptor DC-SIGN Discriminates between Mycobacterium Species through Selective Recognition of the Mannose Caps on Lipoarabinomannan
J. Biol. Chem. 2003 278: 5513-5516. First Published on December 20, 2002; doi:10.1074/jbc.C200586200 [Abstract] [Full Text] [PDF]  

DNA: Replication Repair and Recombination:

Mihai Ciubotaru, Leon M. Ptaszek, Gary A. Baker, Sheila N. Baker, Frank V. Bright, and David G. Schatz

RAG1-DNA Binding in V(D)J Recombination. SPECIFICITY AND DNA-INDUCED CONFORMATIONAL CHANGES REVEALED BY FLUORESCENCE AND CD SPECTROSCOPY
J. Biol. Chem. 2003 278: 5584-5596. First Published on December 17, 2002; doi:10.1074/jbc.M209758200 [Abstract] [Full Text] [PDF]  

Kausiki Datta and Vince J. LiCata

Salt Dependence of DNA binding by Thermus aquaticus and Escherichia coli DNA Polymerases
J. Biol. Chem. 2003 278: 5694-5701. First Published on December 3, 2002; doi:10.1074/jbc.M208133200 [Abstract] [Full Text] [PDF]  

Andrew J. Kurtz and R. Stephen Lloyd

1,N²-Deoxyguanosine Adducts of Acrolein, Crotonaldehyde, and trans-4-Hydroxynonenal Cross-link to Peptides via Schiff Base Linkage
J. Biol. Chem. 2003 278: 5970-5976. First Published on December 26, 2002; doi:10.1074/jbc.M212012200 [Abstract] [Full Text] [PDF]  

Victoria K. Chang, Michael J. Fitch, Justin J. Donato, Tim W. Christensen, A. Margaret Merchant, and Bik K. Tye

Mcm1 Binds Replication Origins
J. Biol. Chem. 2003 278: 6093-6100. First Published on December 6, 2002; doi:10.1074/jbc.M209827200 [Abstract] [Full Text] [PDF]  

Yong Lei Shang, Amanda J. Bodero, and Phang-Lang Chen

NFBD1, a Novel Nuclear Protein with Signature Motifs of FHA and BRCT, and an Internal 41-Amino Acid Repeat Sequence, Is an Early Participant in DNA Damage Response
J. Biol. Chem. 2003 278: 6323-6329. First Published on December 9, 2002; doi:10.1074/jbc.M210749200 [Abstract] [Full Text] [PDF]  

Genes: Structure and Regulation:

Susanne Brenner, Susanna Prösch, Katja Schenke-Layland, Ulrike Riese, Ulrike Gausmann, and Cornelia Platzer

cAMP-induced Interleukin-10 Promoter Activation Depends on CCAAT/Enhancer-binding Protein Expression and Monocytic Differentiation
J. Biol. Chem. 2003 278: 5597-5604. First Published on December 18, 2002; doi:10.1074/jbc.M207448200 [Abstract] [Full Text] [PDF]  

Pawel R. Kiela, Jeffrey LeSueur, James F. Collins, and Fayez K. Ghishan

Transcriptional Regulation of the Rat NHE3 Gene. FUNCTIONAL INTERACTIONS BETWEEN GATA-5 AND Sp FAMILY TRANSCRIPTION FACTORS
J. Biol. Chem. 2003 278: 5659-5668. First Published on December 2, 2002; doi:10.1074/jbc.M209473200 [Abstract] [Full Text] [PDF]  

Julie Deschênes-Furry, Guy Bélanger, Nora Perrone-Bizzozero, and Bernard J. Jasmin

Post-transcriptional Regulation of Acetylcholinesterase mRNAs in Nerve Growth Factor-treated PC12 Cells by the RNA-binding Protein HuD
J. Biol. Chem. 2003 278: 5710-5717. First Published on December 4, 2002; doi:10.1074/jbc.M209383200 [Abstract] [Full Text] [PDF]  

Nicholas Denko, Kara Wernke-Dollries, Amber Buescher Johnson, Ester Hammond, Cheng-Ming Chiang, and Michelle Craig Barton

Hypoxia Actively Represses Transcription by Inducing Negative Cofactor 2 (Dr1/DrAP1) and Blocking Preinitiation Complex Assembly
J. Biol. Chem. 2003 278: 5744-5749. First Published on December 10, 2002; doi:10.1074/jbc.M212534200 [Abstract] [Full Text] [PDF]  

Martha L. Clabby, Trevor A. Robison, Heather F. Quigley, David B. Wilson, and Daniel P. Kelly

Retinoid X Receptor Represses GATA-4-mediated Transcription via a Retinoid-dependent Interaction with the Cardiac-enriched Repressor FOG-2
J. Biol. Chem. 2003 278: 5760-5767. First Published on December 11, 2002; doi:10.1074/jbc.M208173200 [Abstract] [Full Text] [PDF]  

Isabelle Bar, Fadel Tissir, Catherine Lambert de Rouvroit, Olivier De Backer, and André M. Goffinet

The Gene Encoding Disabled-1 (DAB1), the Intracellular Adaptor of the Reelin Pathway, Reveals Unusual Complexity in Human and Mouse
J. Biol. Chem. 2003 278: 5802-5812. First Published on November 21, 2002; doi:10.1074/jbc.M207178200 [Abstract] [Full Text] [PDF]  

Ko Fujimori, Yasushi Fujitani, Keiichi Kadoyama, Haruko Kumanogoh, Koichi Ishikawa, and Yoshihiro Urade

Regulation of Lipocalin-type Prostaglandin D Synthase Gene Expression by Hes-1 through E-box and Interleukin-1 via Two NF-B Elements in Rat Leptomeningeal Cells
J. Biol. Chem. 2003 278: 6018-6026. First Published on December 17, 2002; doi:10.1074/jbc.M208288200 [Abstract] [Full Text] [PDF]  

Abbas Abdollahi, Debra Pisarcik, David Roberts, Jillian Weinstein, Paul Cairns, and Thomas C. Hamilton

LOT1 (PLAGL1/ZAC1), the Candidate Tumor Suppressor Gene at Chromosome 6q24-25, Is Epigenetically Regulated in Cancer
J. Biol. Chem. 2003 278: 6041-6049. First Published on December 6, 2002; doi:10.1074/jbc.M210361200 [Abstract] [Full Text] [PDF]  

Edward E. Schmidt, Alla A. Bondareva, Jay R. Radke, and Mario R. Capecchi

Fundamental Cellular Processes Do Not Require Vertebrate-specific Sequences within the TATA-binding Protein
J. Biol. Chem. 2003 278: 6168-6174. First Published on December 5, 2002; doi:10.1074/jbc.M211205200 [Abstract] [Full Text] [PDF]  

Amy K. Walker and T. Keith Blackwell

A Broad but Restricted Requirement for TAF-5 (Human TAF_II100) for Embryonic Transcription in Caenorhabditis elegans
J. Biol. Chem. 2003 278: 6181-6186. First Published on November 27, 2002; doi:10.1074/jbc.M211056200 [Abstract] [Full Text] [PDF]  

Tomoaki Ishizaki, Masumi Yoshie, Yuji Yaginuma, Tatsuya Tanaka, and Katsuhiro Ogawa

Loss of Igf2 Imprinting in Monoclonal Mouse Hepatic Tumor Cells Is Not Associated with Abnormal Methylation Patterns for the H19, Igf2, and Kvlqt1 Differentially Methylated Regions
J. Biol. Chem. 2003 278: 6222-6228. First Published on December 9, 2002; doi:10.1074/jbc.M207627200 [Abstract] [Full Text] [PDF]  

Gilles Despouy, Jean-Noël Bastie, Sylvie Deshaies, Nicole Balitrand, Alexandra Mazharian, Cécile Rochette-Egly, Christine Chomienne, and Laurent Delva

Cyclin D3 Is a Cofactor of Retinoic Acid Receptors, Modulating Their Activity in the Presence of Cellular Retinoic Acid-binding Protein II
J. Biol. Chem. 2003 278: 6355-6362. First Published on December 12, 2002; doi:10.1074/jbc.M210697200 [Abstract] [Full Text] [PDF]  

Venkat S. R. K. Yedavalli, Monsef Benkirane, and Kuan-Teh Jeang

Tat and Trans-activation-responsive (TAR) RNA-independent Induction of HIV-1 Long Terminal Repeat by Human and Murine Cyclin T1 Requires Sp1
J. Biol. Chem. 2003 278: 6404-6410. First Published on November 27, 2002; doi:10.1074/jbc.M209162200 [Abstract] [Full Text] [PDF]  

Ndiko Ludidi and Chris Gehring

Identification of a Novel Protein with Guanylyl Cyclase Activity in Arabidopsis thaliana
J. Biol. Chem. 2003 278: 6490-6494. First Published on December 12, 2002; doi:10.1074/jbc.M210983200 [Abstract] [Full Text] [PDF]  

RNA: Structure Metabolism and Catalysis:

Zhi-Shun Huang, Wen-Huey Su, Jui-Ling Wang, and Huey-Nan Wu

Selective Strand Annealing and Selective Strand Exchange Promoted by the N-terminal Domain of Hepatitis Delta Antigen
J. Biol. Chem. 2003 278: 5685-5693. First Published on December 3, 2002; doi:10.1074/jbc.M207938200 [Abstract] [Full Text] [PDF]  

Protein Synthesis Post-Translation Modification and Degradation:

Dilip Chandu, Anujith Kumar, and Dipankar Nandi

PepN, the Major Suc-LLVY-AMC-hydrolyzing Enzyme in Escherichia coli, Displays Functional Similarity with Downstream Processing Enzymes in Archaea and Eukarya. IMPLICATIONS IN CYTOSOLIC PROTEIN DEGRADATION
J. Biol. Chem. 2003 278: 5548-5556. First Published on December 12, 2002; doi:10.1074/jbc.M207926200 [Abstract] [Full Text] [PDF]  

Fabien Brossier, Travis J. Jewett, Jennie L. Lovett, and L. David Sibley

C-terminal Processing of the Toxoplasma Protein MIC2 Is Essential for Invasion into Host Cells
J. Biol. Chem. 2003 278: 6229-6234. First Published on December 5, 2002; doi:10.1074/jbc.M209837200 [Abstract] [Full Text] [PDF]  

Romit Majumdar, Amitabha Bandyopadhyay, and Umadas Maitra

Mammalian Translation Initiation Factor eIF1 Functions with eIF1A and eIF3 in the Formation of a Stable 40 S Preinitiation Complex
J. Biol. Chem. 2003 278: 6580-6587. First Published on December 18, 2002; doi:10.1074/jbc.M210357200 [Abstract] [Full Text] [PDF]  

Genomics Proteomics and Bioinformatics:

Simon Allen, Paul Roy Heath, Janine Kirby, Stephen Barrie Wharton, Mark Robert Cookson, Fiona Mhairi Menzies, Rosamonde Elizabeth Banks, and Pamela Jean Shaw

Analysis of the Cytosolic Proteome in a Cell Culture Model of Familial Amyotrophic Lateral Sclerosis Reveals Alterations to the Proteasome, Antioxidant Defenses, and Nitric Oxide Synthetic Pathways
J. Biol. Chem. 2003 278: 6371-6383. First Published on December 9, 2002; doi:10.1074/jbc.M209915200 [Abstract] [Full Text] [PDF]  

Paul J. Adam, Robert Boyd, Kerry L. Tyson, Graham C. Fletcher, Alasdair Stamps, Lindsey Hudson, Helen R. Poyser, Nick Redpath, Matthew Griffiths, Graham Steers, Adrian L. Harris, Sonal Patel, Joanne Berry, Julie A. Loader, R. Reid Townsend, Laurent Daviet, Pierre Legrain, Raj Parekh, and Jonathan A. Terrett

Comprehensive Proteomic Analysis of Breast Cancer Cell Membranes Reveals Unique Proteins with Potential Roles in Clinical Cancer
J. Biol. Chem. 2003 278: 6482-6489. First Published on December 10, 2002; doi:10.1074/jbc.M210184200 [Abstract] [Full Text] [PDF] Supplemental Data  

Protein Structure and Folding:

Dmitry Pavlov, Jack H. Gerson, Tianwei Yu, Larry S. Tobacman, Earl Homsher, and Emil Reisler

The Regulation of Subtilisin-cleaved Actin by Tropomyosin/Troponin
J. Biol. Chem. 2003 278: 5517-5522. First Published on December 4, 2002; doi:10.1074/jbc.M210889200 [Abstract] [Full Text] [PDF]  

Dawn M. Hill, Tina Kasliwal, Elie Schwarz, Andrea M. Hebert, Trina Chen, Elena Gubina, Lei Zhang, and Steven Kozlowski

A Dominant Negative Mutant 2-Microglobulin Blocks the Extracellular Folding of a Major Histocompatibility Complex Class I Heavy Chain
J. Biol. Chem. 2003 278: 5630-5638. First Published on November 25, 2002; doi:10.1074/jbc.M208381200 [Abstract] [Full Text] [PDF]  

Stephan Hobe, Holger Fey, Hans Rogl, and Harald Paulsen

Determination of Relative Chlorophyll Binding Affinities in the Major Light-harvesting Chlorophyll a/b Complex
J. Biol. Chem. 2003 278: 5912-5919. First Published on December 17, 2002; doi:10.1074/jbc.M211145200 [Abstract] [Full Text] [PDF]  

Ashutosh Tiwari and Lawrence J. Hayward

Familial Amyotrophic Lateral Sclerosis Mutants of Copper/Zinc Superoxide Dismutase Are Susceptible to Disulfide Reduction
J. Biol. Chem. 2003 278: 5984-5992. First Published on November 27, 2002; doi:10.1074/jbc.M210419200 [Abstract] [Full Text] [PDF]  

Ty E. Adams, Anne B. Mason, Qing-Yu He, Peter J. Halbrooks, Sara K. Briggs, Valerie C. Smith, Ross T. A. MacGillivray, and Stephen J. Everse

The Position of Arginine 124 Controls the Rate of Iron Release from the N-lobe of Human Serum Transferrin. A STRUCTURAL STUDY
J. Biol. Chem. 2003 278: 6027-6033. First Published on November 27, 2002; doi:10.1074/jbc.M210349200 [Abstract] [Full Text] [PDF]  

Samantha P. Harris, William T. Heller, Marion L. Greaser, Richard L. Moss, and Jill Trewhella

Solution Structure of Heavy Meromyosin by Small-angle Scattering
J. Biol. Chem. 2003 278: 6034-6040. First Published on December 3, 2002; doi:10.1074/jbc.M210558200 [Abstract] [Full Text] [PDF]  

John M. Louis, Rieko Ishima, Issa Nesheiwat, Lewis K. Pannell, Shannon M. Lynch, Dennis A. Torchia, and Angela M. Gronenborn

Revisiting Monomeric HIV-1 Protease. CHARACTERIZATION AND REDESIGN FOR IMPROVED PROPERTIES
J. Biol. Chem. 2003 278: 6085-6092. First Published on December 4, 2002; doi:10.1074/jbc.M209726200 [Abstract] [Full Text] [PDF]  

Mahadevaiah Umashankar, Mathur R. N. Murthy, and Handanahal S. Savithri

Mutation of Interfacial Residues Disrupts Subunit Folding and Particle Assembly of Physalis mottle tymovirus
J. Biol. Chem. 2003 278: 6145-6152. First Published on December 10, 2002; doi:10.1074/jbc.M207992200 [Abstract] [Full Text] [PDF]  

Mita De, Krupakar Jayarapu, Laura Elenich, John J. Monaco, Robert A. Colbert, and Thomas A. Griffin

2 Subunit Propeptides Influence Cooperative Proteasome Assembly
J. Biol. Chem. 2003 278: 6153-6159. First Published on November 26, 2002; doi:10.1074/jbc.M209292200 [Abstract] [Full Text] [PDF]  

Alexis Gautreau, Bruno T. Fievet, Estelle Brault, Claude Antony, Anne Houdusse, Daniel Louvard, and Monique Arpin

Isolation and Characterization of an Aggresome Determinant in the NF2 Tumor Suppressor
J. Biol. Chem. 2003 278: 6235-6242. First Published on December 5, 2002; doi:10.1074/jbc.M210639200 [Abstract] [Full Text] [PDF]  

Kimberly A. McClintock and Gary S. Shaw

A Novel S100 Target Conformation Is Revealed by the Solution Structure of the Ca²⁺-S100B-TRTK-12 Complex
J. Biol. Chem. 2003 278: 6251-6257. First Published on December 11, 2002; doi:10.1074/jbc.M210622200 [Abstract] [Full Text] [PDF]  

Norelle L. Daly, Richard J. Clark, and David J. Craik

Disulfide Folding Pathways of Cystine Knot Proteins. TYING THE KNOT WITHIN THE CIRCULAR BACKBONE OF THE CYCLOTIDES
J. Biol. Chem. 2003 278: 6314-6322. First Published on December 12, 2002; doi:10.1074/jbc.M210492200 [Abstract] [Full Text] [PDF] Supplemental Data  

Markus J. Tamás, Sara Karlgren, Roslyn M. Bill, Kristina Hedfalk, Laura Allegri, Marie Ferreira, Johan M. Thevelein, Jan Rydström, Jonathan G. L. Mullins, and Stefan Hohmann

A Short Regulatory Domain Restricts Glycerol Transport through Yeast Fps1p
J. Biol. Chem. 2003 278: 6337-6345. First Published on December 16, 2002; doi:10.1074/jbc.M209792200 [Abstract] [Full Text] [PDF]  

Eva Ramon, Luis J. del Valle, and Pere Garriga

Unusual Thermal and Conformational Properties of the Rhodopsin Congenital Night Blindness Mutant Thr-94 Ile
J. Biol. Chem. 2003 278: 6427-6432. First Published on December 3, 2002; doi:10.1074/jbc.M210929200 [Abstract] [Full Text] [PDF]  

Dong Young Kim, Dong Ryoung Kim, Sung Chul Ha, Neratur K. Lokanath, Chang Jun Lee, Hye-Yeon Hwang, and Kyeong Kyu Kim

Crystal Structure of the Protease Domain of a Heat-shock Protein HtrA from Thermotoga maritima
J. Biol. Chem. 2003 278: 6543-6551. First Published on November 27, 2002; doi:10.1074/jbc.M208148200 [Abstract] [Full Text] [PDF]  

Yumiko Mishima, Keiko Momma, Wataru Hashimoto, Bunzo Mikami, and Kousaku Murata

Crystal Structure of AlgQ2, a Macromolecule (Alginate)-binding Protein of Sphingomonas sp. A1, Complexed with an Alginate Tetrasaccharide at 1.6-Å Resolution
J. Biol. Chem. 2003 278: 6552-6559. First Published on December 16, 2002; doi:10.1074/jbc.M209932200 [Abstract] [Full Text] [PDF]  

Bin Yang, Ling Gao, Lin Li, Zhixian Lu, Xuejun Fan, Charvi A. Patel, Roger J. Pomerantz, Garrett C. DuBois, and Hui Zhang

Potent Suppression of Viral Infectivity by the Peptides That Inhibit Multimerization of Human Immunodeficiency Virus Type 1 (HIV-1) Vif Proteins
J. Biol. Chem. 2003 278: 6596-6602. First Published on December 11, 2002; doi:10.1074/jbc.M210164200 [Abstract] [Full Text] [PDF]  

Enzyme Catalysis and Regulation:

Niamh X. Cawley, Masao Chino, Alex Maldonado, Yazmin M. Rodriguez, Y. Peng Loh, and Jonathan A. Ellman

Synthesis and Characterization of the First Potent Inhibitor of Yapsin 1. IMPLICATIONS FOR THE STUDY OF YAPSIN-LIKE ENZYMES
J. Biol. Chem. 2003 278: 5523-5530. First Published on December 4, 2002; doi:10.1074/jbc.M207230200 [Abstract] [Full Text] [PDF] Supplemental Data  

Regina Fluhrer, Gerd Multhaup, Andrea Schlicksupp, Masayasu Okochi, Masatoshi Takeda, Sven Lammich, Michael Willem, Gil Westmeyer, Wolfram Bode, Jochen Walter, and Christian Haass

Identification of a -Secretase Activity, Which Truncates Amyloid -Peptide after Its Presenilin-dependent Generation
J. Biol. Chem. 2003 278: 5531-5538. First Published on December 5, 2002; doi:10.1074/jbc.M211485200 [Abstract] [Full Text] [PDF]  

Michael Cashel, Lilian M. Hsu, and V. James Hernandez

Changes in Conserved Region 3 of Escherichia coli ⁷⁰ Reduce Abortive Transcription and Enhance Promoter Escape
J. Biol. Chem. 2003 278: 5539-5547. First Published on December 10, 2002; doi:10.1074/jbc.M211430200 [Abstract] [Full Text] [PDF]  

Gabriel E. Weinreb, Kasturi Mukhopadhyay, Rinku Majumder, and Barry R. Lentz

Cooperative Roles of Factor V_a and Phosphatidylserine-containing Membranes as Cofactors in Prothrombin Activation
J. Biol. Chem. 2003 278: 5679-5684. First Published on November 15, 2002; doi:10.1074/jbc.M208423200 [Abstract] [Full Text] [PDF]  

Andreas Natsch, Hans Gfeller, Peter Gygax, Joachim Schmid, and Gonzalo Acuna

A Specific Bacterial Aminoacylase Cleaves Odorant Precursors Secreted in the Human Axilla
J. Biol. Chem. 2003 278: 5718-5727. First Published on December 4, 2002; doi:10.1074/jbc.M210142200 [Abstract] [Full Text] [PDF]  

Camilla Skouboe, Lotte Bjergbaek, Vibe H. Oestergaard, Morten K. Larsen, Birgitta R. Knudsen, and Anni H. Andersen

A Human Topoisomerase II Heterodimer with Only One ATP Binding Site Can Go through Successive Catalytic Cycles
J. Biol. Chem. 2003 278: 5768-5774. First Published on December 11, 2002; doi:10.1074/jbc.M210332200 [Abstract] [Full Text] [PDF]  

Tomas Dobransky, Dyanne Brewer, Gilles Lajoie, and R. Jane Rylett

Phosphorylation of 69-kDa Choline Acetyltransferase at Threonine 456 in Response to Amyloid- Peptide 1-42
J. Biol. Chem. 2003 278: 5883-5893. First Published on December 16, 2002; doi:10.1074/jbc.M212080200 [Abstract] [Full Text] [PDF]  

Mei Du, Hui-Chun Yeh, Vladimir Berka, Lee-Ho Wang, and Ah-lim Tsai

Redox Properties of Human Endothelial Nitric-oxide Synthase Oxygenase and Reductase Domains Purified from Yeast Expression System
J. Biol. Chem. 2003 278: 6002-6011. First Published on December 11, 2002; doi:10.1074/jbc.M209606200 [Abstract] [Full Text] [PDF]  

Simonida Gencic and David A. Grahame

Nickel in Subunit of the Acetyl-CoA Decarbonylase/Synthase Multienzyme Complex in Methanogens. CATALYTIC PROPERTIES AND EVIDENCE FOR A BINUCLEAR Ni-Ni SITE
J. Biol. Chem. 2003 278: 6101-6110. First Published on December 2, 2002; doi:10.1074/jbc.M210484200 [Abstract] [Full Text] [PDF]  

Alisdair B. Boraston, Emily Kwan, Patrick Chiu, R. Antony J. Warren, and Douglas G. Kilburn

Recognition and Hydrolysis of Noncrystalline Cellulose
J. Biol. Chem. 2003 278: 6120-6127. First Published on November 8, 2002; doi:10.1074/jbc.M209554200 [Abstract] [Full Text] [PDF]  

Andrew S. Robertson, Didier Belorgey, Kathryn S. Lilley, David A. Lomas, David Gubb, and Timothy R. Dafforn

Characterization of the Necrotic Protein That Regulates the Toll-mediated Immune Response in Drosophila
J. Biol. Chem. 2003 278: 6175-6180. First Published on October 31, 2002; doi:10.1074/jbc.M209277200 [Abstract] [Full Text] [PDF]  

Michael Teufel, Vladimir Saudek, Jean-Pierre Ledig, Annie Bernhardt, Sylviane Boularand, Alexandra Carreau, Nigel J. Cairns, Christopher Carter, David J. Cowley, Danielle Duverger, Axel J. Ganzhorn, Chantal Guenet, Blanche Heintzelmann, Veronique Laucher, Claude Sauvage, and Tatiana Smirnova

Sequence Identification and Characterization of Human Carnosinase and a Closely Related Non-specific Dipeptidase
J. Biol. Chem. 2003 278: 6521-6531. First Published on December 6, 2002; doi:10.1074/jbc.M209764200 [Abstract] [Full Text] [PDF]  

Metabolism and Bioenergetics:

Derick Han, Fernando Antunes, Raffaella Canali, Daniel Rettori, and Enrique Cadenas

Voltage-dependent Anion Channels Control the Release of the Superoxide Anion from Mitochondria to Cytosol
J. Biol. Chem. 2003 278: 5557-5563. First Published on December 12, 2002; doi:10.1074/jbc.M210269200 [Abstract] [Full Text] [PDF]  

Giovanni Manfredi, Jennifer Q. Kwong, Josè A. Oca-Cossio, Markus Woischnik, Carl D. Gajewski, Katherine Martushova, Marilena D'Aurelio, Avi L. Friedlich, and Carlos T. Moraes

BCL-2 Improves Oxidative Phosphorylation and Modulates Adenine Nucleotide Translocation in Mitochondria of Cells Harboring Mutant mtDNA
J. Biol. Chem. 2003 278: 5639-5645. First Published on November 12, 2002; doi:10.1074/jbc.M203080200 [Abstract] [Full Text] [PDF]  

Sander M. Houten, Marit S. Schneiders, Ronald J. A. Wanders, and Hans R. Waterham

Regulation of Isoprenoid/Cholesterol Biosynthesis in Cells from Mevalonate Kinase-deficient Patients
J. Biol. Chem. 2003 278: 5736-5743. First Published on December 10, 2002; doi:10.1074/jbc.M206564200 [Abstract] [Full Text] [PDF]  

Cinzia Dello Russo, Vitaliy Gavrilyuk, Guy Weinberg, Angeles Almeida, Juan P. Bolanos, June Palmer, Dale Pelligrino, Elena Galea, and Douglas L. Feinstein

Peroxisome Proliferator-activated Receptor Thiazolidinedione Agonists Increase Glucose Metabolism in Astrocytes
J. Biol. Chem. 2003 278: 5828-5836. First Published on December 16, 2002; doi:10.1074/jbc.M208132200 [Abstract] [Full Text] [PDF]  

Juan A. Quiel and Judith Bender

Glucose Conjugation of Anthranilate by the Arabidopsis UGT74F2 Glucosyltransferase Is Required for Tryptophan Mutant Blue Fluorescence
J. Biol. Chem. 2003 278: 6275-6281. First Published on December 9, 2002; doi:10.1074/jbc.M211822200 [Abstract] [Full Text] [PDF]  

Toshiyuki Koizumi, Hisako Hikiji, Wee Soo Shin, Tsuyoshi Takato, Satoru Fukuda, Takahiro Abe, Noboru Koshikiya, Kuniaki Iwasawa, and Teruhiko Toyo-oka

Cell Density and Growth-dependent Down-regulation of Both Intracellular Calcium Responses to Agonist Stimuli and Expression of Smooth-surfaced Endoplasmic Reticulum in MC3T3-E1 Osteoblast-like Cells
J. Biol. Chem. 2003 278: 6433-6439. First Published on December 5, 2002; doi:10.1074/jbc.M210243200 [Abstract] [Full Text] [PDF]  

Glycobiology and Extracellular Matrices:

Hiroko Iwasaki, Yan Zhang, Kahori Tachibana, Masanori Gotoh, Norihiro Kikuchi, Yeon-Dae Kwon, Akira Togayachi, Takashi Kudo, Tomomi Kubota, and Hisashi Narimatsu

Initiation of O-Glycan Synthesis in IgA1 Hinge Region Is Determined by a Single Enzyme, UDP-N-Acetyl--D-galactosamine:Polypeptide N-Acetylgalactosaminyltransferase 2
J. Biol. Chem. 2003 278: 5613-5621. First Published on November 15, 2002; doi:10.1074/jbc.M211097200 [Abstract] [Full Text] [PDF]  

Paola Spessotto, Marta Cervi, Maria Teresa Mucignat, Gabriella Mungiguerra, Ida Sartoretto, Roberto Doliana, and Alfonso Colombatti

₁ Integrin-dependent Cell Adhesion to EMILIN-1 Is Mediated by the gC1q Domain
J. Biol. Chem. 2003 278: 6160-6167. First Published on November 26, 2002; doi:10.1074/jbc.M208322200 [Abstract] [Full Text] [PDF]  

Mili Kapoor, Honnappa Srinivas, Eaazhisai Kandiah, Emiliano Gemma, Lars Ellgaard, Stefan Oscarson, Ari Helenius, and Avadhesha Surolia

Interactions of Substrate with Calreticulin, an Endoplasmic Reticulum Chaperone
J. Biol. Chem. 2003 278: 6194-6200. First Published on December 2, 2002; doi:10.1074/jbc.M209132200 [Abstract] [Full Text] [PDF] Supplemental Data  

Lipids and Lipoproteins:

Dev K. Singh, Vishwesh Mokashi, C. Lee Elmore, and Todd D. Porter

Phosphorylation of Supernatant Protein Factor Enhances Its Ability to Stimulate Microsomal Squalene Monooxygenase
J. Biol. Chem. 2003 278: 5646-5651. First Published on November 25, 2002; doi:10.1074/jbc.M211750200 [Abstract] [Full Text] [PDF]  

Yu Sun, Mingming Hao, Yi Luo, Chien-ping Liang, David L. Silver, Celina Cheng, Frederick R. Maxfield, and Alan R. Tall

Stearoyl-CoA Desaturase Inhibits ATP-binding Cassette Transporter A1-mediated Cholesterol Efflux and Modulates Membrane Domain Structure
J. Biol. Chem. 2003 278: 5813-5820. First Published on December 12, 2002; doi:10.1074/jbc.M208687200 [Abstract] [Full Text] [PDF]  

Seung Joon Baek, Leigh C. Wilson, Linda C. Hsi, and Thomas E. Eling

Troglitazone, a Peroxisome Proliferator-activated Receptor (PPAR) Ligand, Selectively Induces the Early Growth Response-1 Gene Independently of PPAR. A NOVEL MECHANISM FOR ITS ANTI-TUMORIGENIC ACTIVITY
J. Biol. Chem. 2003 278: 5845-5853. First Published on December 9, 2002; doi:10.1074/jbc.M208394200 [Abstract] [Full Text] [PDF]  

Anna A. Noga, Lori M. Stead, Yang Zhao, Margaret E. Brosnan, John T. Brosnan, and Dennis E. Vance

Plasma Homocysteine Is Regulated by Phospholipid Methylation
J. Biol. Chem. 2003 278: 5952-5955. First Published on December 12, 2002; doi:10.1074/jbc.M212194200 [Abstract] [Full Text] [PDF]  

Taher Nassar, Bruce S. Sachais, Sa'ed Akkawi, Maria Anna Kowalska, Khalil Bdeir, Eran Leitersdorf, Edna Hiss, Leah Ziporen, Michael Aviram, Douglas Cines, Mortimer Poncz, and Abd Al-Roof Higazi

Platelet Factor 4 Enhances the Binding of Oxidized Low-density Lipoprotein to Vascular Wall Cells
J. Biol. Chem. 2003 278: 6187-6193. First Published on December 3, 2002; doi:10.1074/jbc.M208894200 [Abstract] [Full Text] [PDF]  

Avery L. McIntosh, Adalberto M. Gallegos, Barbara P. Atshaves, Stephen M. Storey, Deepak Kannoju, and Friedhelm Schroeder

Fluorescence and Multiphoton Imaging Resolve Unique Structural Forms of Sterol in Membranes of Living Cells
J. Biol. Chem. 2003 278: 6384-6403. First Published on November 26, 2002; doi:10.1074/jbc.M205472200 [Abstract] [Full Text] [PDF]  

Jacques Grober, Stéphanie Lucas, Maria Sörhede-Winzell, Isabelle Zaghini, Aline Mairal, Juan-Antonio Contreras, Philippe Besnard, Cecilia Holm, and Dominique Langin

Hormone-sensitive Lipase Is a Cholesterol Esterase of the Intestinal Mucosa
J. Biol. Chem. 2003 278: 6510-6515. First Published on December 13, 2002; doi:10.1074/jbc.M208513200 [Abstract] [Full Text] [PDF]  

Membrane Transport Structure Function and Biogenesis:

Tomotake Kanki, Mark T. Young, Masao Sakaguchi, Naotaka Hamasaki, and Michael J. A. Tanner

The N-terminal Region of the Transmembrane Domain of Human Erythrocyte Band 3. RESIDUES CRITICAL FOR MEMBRANE INSERTION AND TRANSPORT ACTIVITY
J. Biol. Chem. 2003 278: 5564-5573. First Published on December 12, 2002; doi:10.1074/jbc.M211662200 [Abstract] [Full Text] [PDF]  

Kevin J. Saliba, Richard J. W. Allen, Stephanie Zissis, Patrick G. Bray, Stephen A. Ward, and Kiaran Kirk

Acidification of the Malaria Parasite's Digestive Vacuole by a H⁺-ATPase and a H⁺-pyrophosphatase
J. Biol. Chem. 2003 278: 5605-5612. First Published on November 8, 2002; doi:10.1074/jbc.M208648200 [Abstract] [Full Text] [PDF]  

Benjamin M. Abell, Martin Jung, Jason D. Oliver, Bruce C. Knight, Jens Tyedmers, Richard Zimmermann, and Stephen High

Tail-anchored and Signal-anchored Proteins Utilize Overlapping Pathways during Membrane Insertion
J. Biol. Chem. 2003 278: 5669-5678. First Published on December 2, 2002; doi:10.1074/jbc.M209968200 [Abstract] [Full Text] [PDF]  

Tsuyoshi Nishi, Shoko Kawasaki-Nishi, and Michael Forgac

The First Putative Transmembrane Segment of Subunit c" (Vma16p) of the Yeast V-ATPase Is Not Necessary for Function
J. Biol. Chem. 2003 278: 5821-5827. First Published on December 12, 2002; doi:10.1074/jbc.M209875200 [Abstract] [Full Text] [PDF]  

Michelle T. Harreman, Mary R. Hodel, Patrizia Fanara, Alec E. Hodel, and Anita H. Corbett

The Auto-inhibitory Function of Importin Is Essential in Vivo
J. Biol. Chem. 2003 278: 5854-5863. First Published on December 16, 2002; doi:10.1074/jbc.M210951200 [Abstract] [Full Text] [PDF]  

Atsushi Ikemoto, David G. Bole, and Tetsufumi Ueda

Glycolysis and Glutamate Accumulation into Synaptic Vesicles. ROLE OF GLYCERALDEHYDE PHOSPHATE DEHYDROGENASE AND 3-PHOSPHOGLYCERATE KINASE
J. Biol. Chem. 2003 278: 5929-5940. First Published on December 17, 2002; doi:10.1074/jbc.M211617200 [Abstract] [Full Text] [PDF]  

John Golin, Suresh V. Ambudkar, Michael M. Gottesman, Asif Dominic Habib, John Sczepanski, William Ziccardi, and Leopold May

Studies with Novel Pdr5p Substrates Demonstrate a Strong Size Dependence for Xenobiotic Efflux
J. Biol. Chem. 2003 278: 5963-5969. First Published on December 19, 2002; doi:10.1074/jbc.M210908200 [Abstract] [Full Text] [PDF]  

Elisabeth Le Rumeur, Yann Fichou, Sandrine Pottier, François Gaboriau, Corinne Rondeau-Mouro, Michel Vincent, Jacques Gallay, and Arnaud Bondon

Interaction of Dystrophin Rod Domain with Membrane Phospholipids. EVIDENCE OF A CLOSE PROXIMITY BETWEEN TRYPTOPHAN RESIDUES AND LIPIDS
J. Biol. Chem. 2003 278: 5993-6001. First Published on December 11, 2002; doi:10.1074/jbc.M207321200 [Abstract] [Full Text] [PDF]  

Christine M. Angevine and Robert H. Fillingame

Aqueous Access Channels in Subunit a of Rotary ATP Synthase
J. Biol. Chem. 2003 278: 6066-6074. First Published on December 6, 2002; doi:10.1074/jbc.M210199200 [Abstract] [Full Text] [PDF]  

Manisha Rajebhosale, Sam Greenwood, Jolanta Vidugiriene, Andreas Jeromin, and Sabine Hilfiker

Phosphatidylinositol 4-OH Kinase Is a Downstream Target of Neuronal Calcium Sensor-1 in Enhancing Exocytosis in Neuroendocrine Cells
J. Biol. Chem. 2003 278: 6075-6084. First Published on December 5, 2002; doi:10.1074/jbc.M204702200 [Abstract] [Full Text] [PDF]  

You-Jun Fei, Katsuhisa Inoue, and Vadivel Ganapathy

Structural and Functional Characteristics of Two Sodium-coupled Dicarboxylate Transporters (ceNaDC1 and ceNaDC2) from Caenorhabditis elegans and Their Relevance to Life Span
J. Biol. Chem. 2003 278: 6136-6144. First Published on December 11, 2002; doi:10.1074/jbc.M208763200 [Abstract] [Full Text] [PDF]  

Patrick L. Splinter, Anatoliy I. Masyuk, and Nicholas F. LaRusso

Specific Inhibition of AQP1 Water Channels in Isolated Rat Intrahepatic Bile Duct Units by Small Interfering RNAs
J. Biol. Chem. 2003 278: 6268-6274. First Published on December 4, 2002; doi:10.1074/jbc.M212079200 [Abstract] [Full Text] [PDF]  

Airat Valiakhmetov and David S. Perlin

Molecular Architecture of the Phosphorylation Region of the Yeast Plasma Membrane H⁺-ATPase
J. Biol. Chem. 2003 278: 6330-6336. First Published on December 11, 2002; doi:10.1074/jbc.M208927200 [Abstract] [Full Text] [PDF]  

Martina Gentzsch, Liying Cui, April Mengos, Xiu-bao Chang, Jey-Hsin Chen, and John R. Riordan

The PDZ-binding Chloride Channel ClC-3B Localizes to the Golgi and Associates with Cystic Fibrosis Transmembrane Conductance Regulator-interacting PDZ Proteins
J. Biol. Chem. 2003 278: 6440-6449. First Published on December 5, 2002; doi:10.1074/jbc.M211050200 [Abstract] [Full Text] [PDF]  

Akinola Adisa, Melanie Rug, Nectarios Klonis, Michael Foley, Alan F. Cowman, and Leann Tilley

The Signal Sequence of Exported Protein-1 Directs the Green Fluorescent Protein to the Parasitophorous Vacuole of Transfected Malaria Parasites
J. Biol. Chem. 2003 278: 6532-6542. First Published on November 26, 2002; doi:10.1074/jbc.M207039200 [Abstract] [Full Text] [PDF]  

Hongwei Jia and Parjit Kaur

Biochemical Evidence for Interaction between the Two Nucleotide Binding Domains of ArsA. INSIGHTS FROM MUTANTS AND ATP ANALOGS
J. Biol. Chem. 2003 278: 6603-6609. First Published on December 16, 2002; doi:10.1074/jbc.M211845200 [Abstract] [Full Text] [PDF]  

Toshiro Shigaki, Jon K. Pittman, and Kendal D. Hirschi

Manganese Specificity Determinants in the Arabidopsis Metal/H⁺ Antiporter CAX2
J. Biol. Chem. 2003 278: 6610-6617. First Published on December 22, 2002; doi:10.1074/jbc.M209952200 [Abstract] [Full Text] [PDF]  

Mechanisms Of Signal Transduction:

Alessandro Prinetti, Luisa Basso, Valentina Appierto, Maria Grazia Villani, Manuela Valsecchi, Nicoletta Loberto, Simona Prioni, Vanna Chigorno, Elena Cavadini, Franca Formelli, and Sandro Sonnino

Altered Sphingolipid Metabolism in N-(4-Hydroxyphenyl)- retinamide-resistant A2780 Human Ovarian Carcinoma Cells
J. Biol. Chem. 2003 278: 5574-5583. First Published on December 16, 2002; doi:10.1074/jbc.M207269200 [Abstract] [Full Text] [PDF]  

Tom Vanden Berghe, Michael Kalai, Geert van Loo, Wim Declercq, and Peter Vandenabeele

Disruption of HSP90 Function Reverts Tumor Necrosis Factor-induced Necrosis to Apoptosis
J. Biol. Chem. 2003 278: 5622-5629. First Published on November 18, 2002; doi:10.1074/jbc.M208925200 [Abstract] [Full Text] [PDF]  

Harriët M. Loovers, Kees Veenstra, Helena Snippe, Xavier Pesesse, Christophe Erneux, and Peter J. M. van Haastert

A Diverse Family of Inositol 5-Phosphatases Playing a Role in Growth and Development in Dictyostelium discoideum
J. Biol. Chem. 2003 278: 5652-5658. First Published on December 2, 2002; doi:10.1074/jbc.M208396200 [Abstract] [Full Text] [PDF] Supplemental Data  

Helena L. Palka, Morag Park, and Nicholas K. Tonks

Hepatocyte Growth Factor Receptor Tyrosine Kinase Met Is a Substrate of the Receptor Protein-tyrosine Phosphatase DEP-1
J. Biol. Chem. 2003 278: 5728-5735. First Published on December 9, 2002; doi:10.1074/jbc.M210656200 [Abstract] [Full Text] [PDF]  

Pei-Wen Tsai, Shine-Gwo Shiah, Ming-Tsan Lin, Cheng-Wen Wu, and Min-Liang Kuo

Up-regulation of Vascular Endothelial Growth Factor C in Breast Cancer Cells by Heregulin-1. A CRITICAL ROLE OF p38/NUCLEAR FACTOR-B SIGNALING PATHWAY
J. Biol. Chem. 2003 278: 5750-5759. First Published on December 5, 2002; doi:10.1074/jbc.M204863200 [Abstract] [Full Text] [PDF]  

Gerald V. Denis, Qiang Yu, Peihong Ma, Linda Deeds, Douglas V. Faller, and Chang-Yan Chen

Bcl-2, via Its BH4 Domain, Blocks Apoptotic Signaling Mediated by Mitochondrial Ras
J. Biol. Chem. 2003 278: 5775-5785. First Published on December 10, 2002; doi:10.1074/jbc.M210202200 [Abstract] [Full Text] [PDF]  

Masashige Bando, Makoto Hasegawa, Yasunori Tsuboi, Yasunobu Miyake, Masashi Shiina, Mika Ito, Hiroshi Handa, Kazuo Nagai, and Takao Kataoka

The Mycotoxin Penicillic Acid Inhibits Fas Ligand-induced Apoptosis by Blocking Self-processing of Caspase-8 in Death-inducing Signaling Complex
J. Biol. Chem. 2003 278: 5786-5793. First Published on December 12, 2002; doi:10.1074/jbc.M204178200 [Abstract] [Full Text] [PDF]  

Klaus Podar, Yu-Tzu Tai, Craig E. Cole, Teru Hideshima, Martin Sattler, Angela Hamblin, Nicholas Mitsiades, Robert L. Schlossman, Faith E. Davies, Gareth J. Morgan, Nikhil C. Munshi, Dharminder Chauhan, and Kenneth C. Anderson

Essential Role of Caveolae in Interleukin-6- and Insulin-like Growth Factor I-triggered Akt-1-mediated Survival of Multiple Myeloma Cells
J. Biol. Chem. 2003 278: 5794-5801. First Published on December 12, 2002; doi:10.1074/jbc.M208636200 [Abstract] [Full Text] [PDF]  

Mei Kong, Catherine Mounier, Victor Dumas, and Barry I. Posner

Epidermal Growth Factor-induced DNA Synthesis. KEY ROLE FOR Src PHOSPHORYLATION OF THE DOCKING PROTEIN Gab2
J. Biol. Chem. 2003 278: 5837-5844. First Published on December 2, 2002; doi:10.1074/jbc.M208286200 [Abstract] [Full Text] [PDF]  

Meredith L. L. Leong, Anita C. Maiyar, Brian Kim, Bridget A. O'Keeffe, and Gary L. Firestone

Expression of the Serum- and Glucocorticoid-inducible Protein Kinase, Sgk, Is a Cell Survival Response to Multiple Types of Environmental Stress Stimuli in Mammary Epithelial Cells
J. Biol. Chem. 2003 278: 5871-5882. First Published on December 16, 2002; doi:10.1074/jbc.M211649200 [Abstract] [Full Text] [PDF]  

Sheng Cao, Janet Yao, and Vijay Shah

The Proline-rich Domain of Dynamin-2 Is Responsible for Dynamin-dependent in Vitro Potentiation of Endothelial Nitric-oxide Synthase Activity via Selective Effects on Reductase Domain Function
J. Biol. Chem. 2003 278: 5894-5901. First Published on December 16, 2002; doi:10.1074/jbc.M212546200 [Abstract] [Full Text] [PDF]  

Natsumi Saito, Keiko Matsubara, Masakatsu Watanabe, Fumio Kato, and Kozo Ochi

Genetic and Biochemical Characterization of EshA, a Protein That Forms Large Multimers and Affects Developmental Processes in Streptomyces griseus
J. Biol. Chem. 2003 278: 5902-5911. First Published on December 17, 2002; doi:10.1074/jbc.M208564200 [Abstract] [Full Text] [PDF]  

Beth Coyle, Caroline Freathy, Timothy W. Gant, Ruth A. Roberts, and Kelvin Cain

Characterization of the Transforming Growth Factor-₁-induced Apoptotic Transcriptome in FaO Hepatoma Cells
J. Biol. Chem. 2003 278: 5920-5928. First Published on December 17, 2002; doi:10.1074/jbc.M211300200 [Abstract] [Full Text] [PDF] Supplemental Data  

James Witowsky, Amy Abell, Nancy Lassignal Johnson, Gary L. Johnson, and Bruce D. Cuevas

MEKK1 Is Required for Inducible Urokinase-type Plasminogen Activator Expression
J. Biol. Chem. 2003 278: 5941-5946. First Published on December 17, 2002; doi:10.1074/jbc.M212363200 [Abstract] [Full Text] [PDF]  

Baldwin C. Mak, Ken-Ichi Takemaru, Heidi L. Kenerson, Randall T. Moon, and Raymond S. Yeung

The Tuberin-Hamartin Complex Negatively Regulates -Catenin Signaling Activity
J. Biol. Chem. 2003 278: 5947-5951. First Published on January 2, 2003; doi:10.1074/jbc.C200473200 [Abstract] [Full Text] [PDF]  

Ulrich Laufs, Oliver Adam, Kerstin Strehlow, Sven Wassmann, Christian Konkol, Kerstin Laufs, Werner Schmidt, Michael Böhm, and Georg Nickenig

Down-regulation of Rac-1 GTPase by Estrogen
J. Biol. Chem. 2003 278: 5956-5962. First Published on December 18, 2002; doi:10.1074/jbc.M209813200 [Abstract] [Full Text] [PDF]  

Akira Sakakibara, Seisuke Hattori, Shun Nakamura, and Takuya Katagiri

A Novel Hematopoietic Adaptor Protein, Chat-H, Positively Regulates T Cell Receptor-mediated Interleukin-2 Production by Jurkat Cells
J. Biol. Chem. 2003 278: 6012-6017. First Published on December 14, 2002; doi:10.1074/jbc.M207942200 [Abstract] [Full Text] [PDF]  

Rachel Sterne-Marr, John J. G. Tesmer, Peter W. Day, RoseAnn P. Stracquatanio, Jill-Ann E. Cilente, Katharine E. O'Connor, Alexey N. Pronin, Jeffrey L. Benovic, and Philip B. Wedegaertner

G Protein-coupled Receptor Kinase 2/G_q/11 Interaction. A NOVEL SURFACE ON A REGULATOR OF G PROTEIN SIGNALING HOMOLOGY DOMAIN FOR BINDING G SUBUNITS
J. Biol. Chem. 2003 278: 6050-6058. First Published on November 8, 2002; doi:10.1074/jbc.M208787200 [Abstract] [Full Text] [PDF]  

Jiefei Tong, Sabine Elowe, Piers Nash, and Tony Pawson

Manipulation of EphB2 Regulatory Motifs and SH2 Binding Sites Switches MAPK Signaling and Biological Activity
J. Biol. Chem. 2003 278: 6111-6119. First Published on December 16, 2002; doi:10.1074/jbc.M208972200 [Abstract] [Full Text] [PDF]  

Cristina Croci, Johann Helmut Brandstätter, and Ralf Enz

ZIP3, a New Splice Variant of the PKC--interacting Protein Family, Binds to GABA_C Receptors, PKC-, and Kv2
J. Biol. Chem. 2003 278: 6128-6135. First Published on November 12, 2002; doi:10.1074/jbc.M205162200 [Abstract] [Full Text] [PDF]  

Georg Felix and Thomas Boller

Molecular Sensing of Bacteria in Plants. THE HIGHLY CONSERVED RNA-BINDING MOTIF RNP-1 OF BACTERIAL COLD SHOCK PROTEINS IS RECOGNIZED AS AN ELICITOR SIGNAL IN TOBACCO
J. Biol. Chem. 2003 278: 6201-6208. First Published on December 5, 2002; doi:10.1074/jbc.M209880200 [Abstract] [Full Text] [PDF] Supplemental Data  

Ganapati H. Mahabeleshwar and Gopal C. Kundu

Syk, a Protein-tyrosine Kinase, Suppresses the Cell Motility and Nuclear Factor B-mediated Secretion of Urokinase Type Plasminogen Activator by Inhibiting the Phosphatidylinositol 3'-Kinase Activity in Breast Cancer Cells
J. Biol. Chem. 2003 278: 6209-6221. First Published on December 10, 2002; doi:10.1074/jbc.M208905200 [Abstract] [Full Text] [PDF]  

Akira Tohgo, Eric W. Choy, Diane Gesty-Palmer, Kristen L. Pierce, Stephane Laporte, Robert H. Oakley, Marc G. Caron, Robert J. Lefkowitz, and Louis M. Luttrell

The Stability of the G Protein-coupled Receptor--Arrestin Interaction Determines the Mechanism and Functional Consequence of ERK Activation
J. Biol. Chem. 2003 278: 6258-6267. First Published on December 6, 2002; doi:10.1074/jbc.M212231200 [Abstract] [Full Text] [PDF]  

Catherine Waters, Balwinder Sambi, Kok-Choi Kong, Dawn Thompson, Stuart M. Pitson, Susan Pyne, and Nigel J. Pyne

Sphingosine 1-Phosphate and Platelet-derived Growth Factor (PDGF) Act via PDGF Receptor-Sphingosine 1-Phosphate Receptor Complexes in Airway Smooth Muscle Cells
J. Biol. Chem. 2003 278: 6282-6290. First Published on December 11, 2002; doi:10.1074/jbc.M208560200 [Abstract] [Full Text] [PDF]  

Susana Santos Correia, Carlos Bandeira Duarte, Carlos José Faro, Euclides Vieira Pires, and Ana Luísa Carvalho

Protein Kinase C Associates Directly with the GluR4 -Amino-3-hydroxy-5-methyl-4-isoxazole Propionate Receptor Subunit. EFFECT ON RECEPTOR PHOSPHORYLATION
J. Biol. Chem. 2003 278: 6307-6313. First Published on December 5, 2002; doi:10.1074/jbc.M205587200 [Abstract] [Full Text] [PDF]  

Ralph Graichen, Jonas Sandstedt, Eyleen L. K. Goh, Olle G. P. Isaksson, Jan Törnell, and Peter E. Lobie

The Growth Hormone-binding Protein Is a Location-dependent Cytokine Receptor Transcriptional Enhancer
J. Biol. Chem. 2003 278: 6346-6354. First Published on December 17, 2002; doi:10.1074/jbc.M207546200 [Abstract] [Full Text] [PDF]  

Ping Wang, Hua Gao, Yanxiang Ni, Beibei Wang, Yalan Wu, Lili Ji, Linhua Qin, Lan Ma, and Gang Pei

-Arrestin 2 Functions as a G-Protein-coupled Receptor-activated Regulator of Oncoprotein Mdm2
J. Biol. Chem. 2003 278: 6363-6370. First Published on December 17, 2002; doi:10.1074/jbc.M210350200 [Abstract] [Full Text] [PDF]  

Norio Komatsu, Tomoko Watanabe, Mie Uchida, Masaki Mori, Keita Kirito, Satoru Kikuchi, Qifa Liu, Tetsuzo Tauchi, Keisuke Miyazawa, Hitoshi Endo, Tadashi Nagai, and Keiya Ozawa

A Member of Forkhead Transcription Factor FKHRL1 Is a Downstream Effector of STI571-induced Cell Cycle Arrest in BCR-ABL-expressing Cells
J. Biol. Chem. 2003 278: 6411-6419. First Published on November 26, 2002; doi:10.1074/jbc.M211562200 [Abstract] [Full Text] [PDF]  

Christi Weston, Chris Gordon, Getu Teressa, Eldad Hod, Xiang-Dong Ren, and Joav Prives

Cooperative Regulation by Rac and Rho of Agrin-induced Acetylcholine Receptor Clustering in Muscle Cells
J. Biol. Chem. 2003 278: 6450-6455. First Published on December 6, 2002; doi:10.1074/jbc.M210249200 [Abstract] [Full Text] [PDF]  

Atsushi Oda, Ikuo Wada, Koichi Miura, Katsuya Okawa, Toshihiko Kadoya, Takashi Kato, Hiroshi Nishihara, Masae Maeda, Shinya Tanaka, Kazuo Nagashima, Chiaki Nishitani, Kazuhiko Matsuno, Masaho Ishino, Laura M. Machesky, Hiroyoshi Fujita, and Paul Randazzo

CrkL Directs ASAP1 to Peripheral Focal Adhesions
J. Biol. Chem. 2003 278: 6456-6460. First Published on January 8, 2003; doi:10.1074/jbc.M210817200 [Abstract] [Full Text] [PDF]  

Makiko Otsuki, Toshiki Itoh, and Tadaomi Takenawa

Neural Wiskott-Aldrich Syndrome Protein Is Recruited to Rafts and Associates with Endophilin A in Response to Epidermal Growth Factor
J. Biol. Chem. 2003 278: 6461-6469. First Published on December 10, 2002; doi:10.1074/jbc.M207433200 [Abstract] [Full Text] [PDF]  

Ning-Hui Cheng and Kendal D. Hirschi

Cloning and Characterization of CXIP1, a Novel PICOT Domain-containing Arabidopsis Protein That Associates with CAX1
J. Biol. Chem. 2003 278: 6503-6509. First Published on December 11, 2002; doi:10.1074/jbc.M210883200 [Abstract] [Full Text] [PDF]  

Jian Yang, Lijun Liu, Dandan He, Xi Song, Xiaoshan Liang, Zhizhuang Joe Zhao, and G. Wayne Zhou

Crystal Structure of Human Protein-tyrosine Phosphatase SHP-1
J. Biol. Chem. 2003 278: 6516-6520. First Published on December 13, 2002; doi:10.1074/jbc.M210430200 [Abstract] [Full Text] [PDF]  

William F. Schwindinger, Kelly S. Betz, Kathryn E. Giger, Angela Sabol, Sarah K. Bronson, and Janet D. Robishaw

Loss of G Protein ₇ Alters Behavior and Reduces Striatal _olf Level and cAMP Production
J. Biol. Chem. 2003 278: 6575-6579. First Published on December 17, 2002; doi:10.1074/jbc.M211132200 [Abstract] [Full Text] [PDF]  

James J. Collier, Thuy-Trang T. Doan, Marc C. Daniels, Jill R. Schurr, Jay K. Kolls, and Donald K. Scott

c-Myc Is Required for the Glucose-mediated Induction of Metabolic Enzyme Genes
J. Biol. Chem. 2003 278: 6588-6595. First Published on December 11, 2002; doi:10.1074/jbc.M208011200 [Abstract] [Full Text] [PDF]  

Molecular Basis Of Cell and Developmental Biology:

Oriol Roda, M. Luz Valero, Sandra Peiró, David Andreu, Francisco X. Real, and Pilar Navarro

New Insights into the tPA-Annexin A2 Interaction. IS ANNEXIN A2 CYS⁸ THE SOLE REQUIREMENT FOR THIS ASSOCIATION?
J. Biol. Chem. 2003 278: 5702-5709. First Published on December 4, 2002; doi:10.1074/jbc.M207605200 [Abstract] [Full Text] [PDF]  

Masato Taoka, Tohru Ichimura, Akiko Wakamiya-Tsuruta, Yoshiaki Kubota, Takeshi Araki, Takashi Obinata, and Toshiaki Isobe

V-1, a Protein Expressed Transiently during Murine Cerebellar Development, Regulates Actin Polymerization via Interaction with Capping Protein
J. Biol. Chem. 2003 278: 5864-5870. First Published on December 16, 2002; doi:10.1074/jbc.M211509200 [Abstract] [Full Text] [PDF]  

Madhulika Srivastava, Ella Frolova, Brian Rottinghaus, Steven P. Boe, Alexander Grinberg, Eric Lee, Paul E. Love, and Karl Pfeifer

Imprint Control Element-mediated Secondary Methylation Imprints at the Igf2/H19 Locus
J. Biol. Chem. 2003 278: 5977-5983. First Published on September 20, 2002; doi:10.1074/jbc.M208437200 [Abstract] [Full Text] [PDF]  

Michael Gotthardt, Robert E. Hammer, Norbert Hübner, Jan Monti, Christian C. Witt, Mark McNabb, James A. Richardson, Henk Granzier, Siegfried Labeit, and Joachim Herz

Conditional Expression of Mutant M-line Titins Results in Cardiomyopathy with Altered Sarcomere Structure
J. Biol. Chem. 2003 278: 6059-6065. First Published on December 2, 2002; doi:10.1074/jbc.M211723200 [Abstract] [Full Text] [PDF]  

Michael J. Thomenius, Nancy S. Wang, Edmunds Z. Reineks, Zhengqi Wang, and Clark W. Distelhorst

Bcl-2 on the Endoplasmic Reticulum Regulates Bax Activity by Binding to BH3-only Proteins
J. Biol. Chem. 2003 278: 6243-6250. First Published on December 10, 2002; doi:10.1074/jbc.M208878200 [Abstract] [Full Text] [PDF]  

Seho Kim, Jaewon Ko, Hyewon Shin, Jae-Ran Lee, Chunghun Lim, Jin-Hee Han, Wilko D. Altrock, Craig C. Garner, Eckart D. Gundelfinger, Richard T. Premont, Bong-Kiun Kaang, and Eunjoon Kim

The GIT Family of Proteins Forms Multimers and Associates with the Presynaptic Cytomatrix Protein Piccolo
J. Biol. Chem. 2003 278: 6291-6300. First Published on December 6, 2002; doi:10.1074/jbc.M212287200 [Abstract] [Full Text] [PDF]  

Reiko Iida, Toshihiro Yasuda, Etsuko Tsubota, Hisakazu Takatsuka, Mika Masuyama, Takasumi Matsuki, and Koichiro Kishi

M-LP, Mpv17-like Protein, Has a Peroxisomal Membrane Targeting Signal Comprising a Transmembrane Domain and a Positively Charged Loop and Up-regulates Expression of the Manganese Superoxide Dismutase Gene
J. Biol. Chem. 2003 278: 6301-6306. First Published on December 5, 2002; doi:10.1074/jbc.M210886200 [Abstract] [Full Text] [PDF]  

María C. Touz, Hugo D. Luján, Stanley F. Hayes, and Theodore E. Nash

Sorting of Encystation-specific Cysteine Protease to Lysosome-like Peripheral Vacuoles in Giardia lamblia Requires a Conserved Tyrosine-based Motif
J. Biol. Chem. 2003 278: 6420-6426. First Published on December 3, 2002; doi:10.1074/jbc.M208354200 [Abstract] [Full Text] [PDF] Supplemental Data  

Radhika Nair and Chandrima Shaha

Diethylstilbestrol Induces Rat Spermatogenic Cell Apoptosis in Vivo through Increased Expression of Spermatogenic Cell Fas/FasL System
J. Biol. Chem. 2003 278: 6470-6481. First Published on December 10, 2002; doi:10.1074/jbc.M209319200 [Abstract] [Full Text] [PDF]  

Åsa Fransson, Aino Ruusala, and Pontus Aspenström

Atypical Rho GTPases Have Roles in Mitochondrial Homeostasis and Apoptosis
J. Biol. Chem. 2003 278: 6495-6502. First Published on December 12, 2002; doi:10.1074/jbc.M208609200 [Abstract] [Full Text] [PDF]  

Dylan Sweetman, Terry Smith, Elizabeth R. Farrell, Andrew Chantry, and Andrea Münsterberg

The Conserved Glutamine-rich Region of Chick Csal1 and Csal3 Mediates Protein Interactions with Other Spalt Family Members. IMPLICATIONS FOR TOWNES-BROCKS SYNDROME
J. Biol. Chem. 2003 278: 6560-6566. First Published on December 13, 2002; doi:10.1074/jbc.M209066200 [Abstract] [Full Text] [PDF]  

Daniel Bouvard, Lucile Vignoud, Sandra Dupé-Manet, Nadia Abed, Henri-Noël Fournier, Carole Vincent-Monegat, Saverio Francesco Retta, Reinhard Fässler, and Marc R. Block

Disruption of Focal Adhesions by Integrin Cytoplasmic Domain-associated Protein-1
J. Biol. Chem. 2003 278: 6567-6574. First Published on December 7, 2002; doi:10.1074/jbc.M211258200 [Abstract] [Full Text] [PDF]  

Additions and Corrections:

Alexis A. Diwa and Joel G. Belasco

Critical features of a conserved RNA stem-loop important for feedback regulation of RNase E synthesis.
J. Biol. Chem. 2003 278: 6618. [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.