JBC -- Table of Contents (Apr 16 2004, 279, (16))

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Accelerated Publications:

Noriko Machida, Masato Umikawa, Kimiko Takei, Nariko Sakima, Bat-Erdene Myagmar, Kiyohito Taira, Hiroshi Uezato, Yoshihide Ogawa, and Ken-ichi Kariya: Mitogen-activated Protein Kinase Kinase Kinase Kinase 4 as a Putative Effector of Rap2 to Activate the c-Jun N-terminal Kinase
J. Biol. Chem. 2004 279: 15711-15714. First Published on February 13, 2004; doi:10.1074/jbc.C300542200 [Abstract] [Full Text] [PDF]

Ligong Chen, Carmen Klass, and Anne Woods: Syndecan-2 Regulates Transforming Growth Factor- ${beta}$ Signaling
J. Biol. Chem. 2004 279: 15715-15718. First Published on February 19, 2004; doi:10.1074/jbc.C300430200 [Abstract] [Full Text] [PDF]

Susan W. Y. Cheng, Lee G. D. Fryer, David Carling, and Peter R. Shepherd: Thr²⁴⁴⁶ Is a Novel Mammalian Target of Rapamycin (mTOR) Phosphorylation Site Regulated by Nutrient Status
J. Biol. Chem. 2004 279: 15719-15722. First Published on February 17, 2004; doi:10.1074/jbc.C300534200 [Abstract] [Full Text] [PDF]

DNA: Replication, Repair, and Recombination:

Karen Fien, Young-Sik Cho, Joon-Kyu Lee, Santanu Raychaudhuri, Inger Tappin, and Jerard Hurwitz: Primer Utilization by DNA Polymerase ${alpha}$ -Primase Is Influenced by Its Interaction with Mcm10p
J. Biol. Chem. 2004 279: 16144-16153. First Published on February 6, 2004; doi:10.1074/jbc.M400142200 [Abstract] [Full Text] [PDF]

D. Alwyn Dart, Kate E. Adams, Ildem Akerman, and Nicholas D. Lakin: Recruitment of the Cell Cycle Checkpoint Kinase ATR to Chromatin during S-phase
J. Biol. Chem. 2004 279: 16433-16440. First Published on February 9, 2004; doi:10.1074/jbc.M314212200 [Abstract] [Full Text] [PDF]

Aleksi Lähdesmäki, A. Malcolm R. Taylor, Krystyna H. Chrzanowska, and Qiang Pan-Hammarström: Delineation of the Role of the Mre11 Complex in Class Switch Recombination
J. Biol. Chem. 2004 279: 16479-16487. First Published on January 26, 2004; doi:10.1074/jbc.M312796200 [Abstract] [Full Text] [PDF]

Eriko Matsui, Junko Abe, Hideshi Yokoyama, and Ikuo Matsui: Aromatic Residues Located Close to the Active Center Are Essential for the Catalytic Reaction of Flap Endonuclease-1 from Hyperthermophilic Archaeon Pyrococcus horikoshii
J. Biol. Chem. 2004 279: 16687-16696. First Published on January 23, 2004; doi:10.1074/jbc.M313695200 [Abstract] [Full Text] [PDF]

Eric C. Greene and Kiyoshi Mizuuchi: Visualizing the Assembly and Disassembly Mechanisms of the MuB Transposition Targeting Complex
J. Biol. Chem. 2004 279: 16736-16743. First Published on February 9, 2004; doi:10.1074/jbc.M311883200 [Abstract] [Full Text] [PDF]

Genes: Structure and Regulation:

Kevin L. Abrams, Junwang Xu, Celine Nativelle-Serpentini, Shabnam Dabirshahsahebi, and Melissa B. Rogers: An Evolutionary and Molecular Analysis of Bmp2 Expression
J. Biol. Chem. 2004 279: 15916-15928. First Published on February 2, 2004; doi:10.1074/jbc.M313531200 [Abstract] [Full Text] [PDF]

Ana Poveda, Mercè Pamblanco, Stefan Tafrov, Vicente Tordera, Rolf Sternglanz, and Ramon Sendra: Hif1 Is a Component of Yeast Histone Acetyltransferase B, a Complex Mainly Localized in the Nucleus
J. Biol. Chem. 2004 279: 16033-16043. First Published on February 3, 2004; doi:10.1074/jbc.M314228200 [Abstract] [Full Text] [PDF]

Ping Xu, Patricia A. LaVallee, Jun J. Lin, and John R. Hoidal: Characterization of Proteins Binding to E-box/Ku86 Sites and Function of Ku86 in Transcriptional Regulation of the Human Xanthine Oxidoreductase Gene
J. Biol. Chem. 2004 279: 16057-16063. First Published on February 4, 2004; doi:10.1074/jbc.M305856200 [Abstract] [Full Text] [PDF]

M. Joseph Scobey, Charity A. Fix, and William H. Walker: The Id2 Transcriptional Repressor Is Induced by Follicle-stimulating Hormone and cAMP
J. Biol. Chem. 2004 279: 16064-16070. First Published on February 4, 2004; doi:10.1074/jbc.M309298200 [Abstract] [Full Text] [PDF]

Sheng-Hao Chao, Josephine N. Harada, Francie Hyndman, Xiaoqi Gao, Christian G. Nelson, Sumit K. Chanda, and Jeremy S. Caldwell: PDX1, a Cellular Homeoprotein, Binds to and Regulates the Activity of Human Cytomegalovirus Immediate Early Promoter
J. Biol. Chem. 2004 279: 16111-16120. First Published on February 5, 2004; doi:10.1074/jbc.M312304200 [Abstract] [Full Text] [PDF]

Rocky Pramanik, Trine N. Jørgensen, Hong Xin, Brian L. Kotzin, and Divaker Choubey: Interleukin-6 Induces Expression of Ifi202, an Interferon-inducible Candidate Gene for Lupus Susceptibility
J. Biol. Chem. 2004 279: 16121-16127. First Published on February 5, 2004; doi:10.1074/jbc.M313140200 [Abstract] [Full Text] [PDF]

Natalie M. Stano and Smita S. Patel: T7 Lysozyme Represses T7 RNA Polymerase Transcription by Destabilizing the Open Complex during Initiation
J. Biol. Chem. 2004 279: 16136-16143. First Published on February 5, 2004; doi:10.1074/jbc.M400139200 [Abstract] [Full Text] [PDF] Supplemental Data

Philippe Gervois, Robert Kleemann, Antoine Pilon, Frédéric Percevault, Wolfgang Koenig, Bart Staels, and Teake Kooistra: Global Suppression of IL-6-induced Acute Phase Response Gene Expression after Chronic in Vivo Treatment with the Peroxisome Proliferator-activated Receptor- ${alpha}$ Activator Fenofibrate
J. Biol. Chem. 2004 279: 16154-16160. First Published on February 5, 2004; doi:10.1074/jbc.M400346200 [Abstract] [Full Text] [PDF]

Marc M. S. M. Wösten, Jaap A. Wagenaar, and Jos P. M. van Putten: The FlgS/FlgR Two-component Signal Transduction System Regulates the fla Regulon in Campylobacter jejuni
J. Biol. Chem. 2004 279: 16214-16222. First Published on February 11, 2004; doi:10.1074/jbc.M400357200 [Abstract] [Full Text] [PDF]

Fabrice Morel, Claudine Rauch, Elise Petit, Amélie Piton, Nathalie Theret, Brian Coles, and André Guillouzo: Gene and Protein Characterization of the Human Glutathione S-Transferase Kappa and Evidence for a Peroxisomal Localization
J. Biol. Chem. 2004 279: 16246-16253. First Published on January 23, 2004; doi:10.1074/jbc.M313357200 [Abstract] [Full Text] [PDF]

Marie-Bernard Debril, Laurent Gelman, Elisabeth Fayard, Jean-Sébastien Annicotte, Stéphane Rocchi, and Johan Auwerx: Transcription Factors and Nuclear Receptors Interact with the SWI/SNF Complex through the BAF60c Subunit
J. Biol. Chem. 2004 279: 16677-16686. First Published on December 29, 2003; doi:10.1074/jbc.M312288200 [Abstract] [Full Text] [PDF]

Joseph H. Jeong, Joshua Orvis, Jong Wook Kim, Curtis P. McMurtrey, Rolf Renne, and Dirk P. Dittmer: Regulation and Autoregulation of the Promoter for the Latency-associated Nuclear Antigen of Kaposi's Sarcoma-associated Herpesvirus
J. Biol. Chem. 2004 279: 16822-16831. First Published on January 24, 2004; doi:10.1074/jbc.M312801200 [Abstract] [Full Text] [PDF]

Varsha S. Likhite, Emily I. Cass, Scott D. Anderson, John R. Yates, and Ann M. Nardulli: Interaction of Estrogen Receptor ${alpha}$ with 3-Methyladenine DNA Glycosylase Modulates Transcription and DNA Repair
J. Biol. Chem. 2004 279: 16875-16882. First Published on February 3, 2004; doi:10.1074/jbc.M313155200 [Abstract] [Full Text] [PDF]

RNA: Structure, Metabolism, and Catalysis:

Timothy P. Ellis, Kevin G. Helfenbein, Alexander Tzagoloff, and Carol L. Dieckmann: Aep3p Stabilizes the Mitochondrial Bicistronic mRNA Encoding Subunits 6 and 8 of the H⁺-translocating ATP Synthase of Saccharomyces cerevisiae
J. Biol. Chem. 2004 279: 15728-15733. First Published on January 23, 2004; doi:10.1074/jbc.M314162200 [Abstract] [Full Text] [PDF]

Protein Synthesis, Post-Translation Modification, and Degradation:

Laure Yatime, Emmanuelle Schmitt, Sylvain Blanquet, and Yves Mechulam: Functional Molecular Mapping of Archaeal Translation Initiation Factor 2
J. Biol. Chem. 2004 279: 15984-15993. First Published on February 3, 2004; doi:10.1074/jbc.M311561200 [Abstract] [Full Text] [PDF]

Zhuo Zhang, Hui Wang, Mao Li, Sudhir Agrawal, Xinbin Chen, and Ruiwen Zhang: MDM2 Is a Negative Regulator of p21^WAF1/CIP1, Independent of p53
J. Biol. Chem. 2004 279: 16000-16006. First Published on February 3, 2004; doi:10.1074/jbc.M312264200 [Abstract] [Full Text] [PDF]

Jun Onodera and Yoshinori Ohsumi: Ald6p Is a Preferred Target for Autophagy in Yeast, Saccharomyces cerevisiae
J. Biol. Chem. 2004 279: 16071-16076. First Published on February 4, 2004; doi:10.1074/jbc.M312706200 [Abstract] [Full Text] [PDF]

Jennifer S. Isaacs, Yun-Jin Jung, and Len Neckers: Aryl Hydrocarbon Nuclear Translocator (ARNT) Promotes Oxygen-independent Stabilization of Hypoxia-inducible Factor-1 ${alpha}$ by Modulating an Hsp90-dependent Regulatory Pathway
J. Biol. Chem. 2004 279: 16128-16135. First Published on February 5, 2004; doi:10.1074/jbc.M313342200 [Abstract] [Full Text] [PDF]

Takayuki Ueno, Stig Linder, Cheng-Lun Na, Ward R. Rice, Jan Johansson, and Timothy E. Weaver: Processing of Pulmonary Surfactant Protein B by Napsin and Cathepsin H
J. Biol. Chem. 2004 279: 16178-16184. First Published on February 6, 2004; doi:10.1074/jbc.M312029200 [Abstract] [Full Text] [PDF]

Mark Steffen Hipp, Shahri Raasi, Marcus Groettrup, and Gunter Schmidtke: NEDD8 Ultimate Buster-1L Interacts with the Ubiquitin-like Protein FAT10 and Accelerates Its Degradation
J. Biol. Chem. 2004 279: 16503-16510. First Published on February 2, 2004; doi:10.1074/jbc.M310114200 [Abstract] [Full Text] [PDF]

Young-Tae Lee, Jaison Jacob, Wojciech Michowski, Marcin Nowotny, Jacek Kuznicki, and Walter J. Chazin: Human Sgt1 Binds HSP90 through the CHORD-Sgt1 Domain and Not the Tetratricopeptide Repeat Domain
J. Biol. Chem. 2004 279: 16511-16517. First Published on February 3, 2004; doi:10.1074/jbc.M400215200 [Abstract] [Full Text] [PDF]

Sylvain de Breyne, Romaine Stalder Monney, and Joseph Curran: Proteolytic Processing and Translation Initiation: TWO INDEPENDENT MECHANISMS FOR THE EXPRESSION OF THE SENDAI VIRUS Y PROTEINS
J. Biol. Chem. 2004 279: 16571-16580. First Published on January 22, 2004; doi:10.1074/jbc.M312391200 [Abstract] [Full Text] [PDF]

Anna Bergman, Emil M. Hansson, Sharon E. Pursglove, Mark R. Farmery, Lars Lannfelt, Urban Lendahl, Johan Lundkvist, and Jan Näslund: Pen-2 Is Sequestered in the Endoplasmic Reticulum and Subjected to Ubiquitylation and Proteasome-mediated Degradation in the Absence of Presenilin
J. Biol. Chem. 2004 279: 16744-16753. First Published on January 14, 2004; doi:10.1074/jbc.M313999200 [Abstract] [Full Text] [PDF]

Silvio Notari, Sabina Capellari, Armin Giese, Ingo Westner, Agostino Baruzzi, Bernardino Ghetti, Pierluigi Gambetti, Hans A. Kretzschmar, and Piero Parchi: Effects of Different Experimental Conditions on the PrP^Sc Core Generated by Protease Digestion: IMPLICATIONS FOR STRAIN TYPING AND MOLECULAR CLASSIFICATION OF CJD
J. Biol. Chem. 2004 279: 16797-16804. First Published on January 29, 2004; doi:10.1074/jbc.M313220200 [Abstract] [Full Text] [PDF]

Steve Elliott, David Chang, Evelyne Delorme, Tamer Eris, and Tony Lorenzini: Structural Requirements for Additional N-Linked Carbohydrate on Recombinant Human Erythropoietin
J. Biol. Chem. 2004 279: 16854-16862. First Published on February 2, 2004; doi:10.1074/jbc.M311095200 [Abstract] [Full Text] [PDF]

Protein Structure and Folding:

Yo-hei Watanabe and Masasuke Yoshida: Trigonal DnaK-DnaJ Complex Versus Free DnaK and DnaJ: HEAT STRESS CONVERTS THE FORMER TO THE LATTER, AND ONLY THE LATTER CAN DO DISAGGREGATION IN COOPERATION WITH ClpB
J. Biol. Chem. 2004 279: 15723-15727. First Published on January 16, 2004; doi:10.1074/jbc.M308782200 [Abstract] [Full Text] [PDF]

Dror Avisar, Menahem Keller, Ehud Gazit, Evgenia Prudovsky, Baruch Sneh, and Aviah Zilberstein: The Role of Bacillus thuringiensis Cry1C and Cry1E Separate Structural Domains in the Interaction with Spodoptera littoralis Gut Epithelial Cells
J. Biol. Chem. 2004 279: 15779-15786. First Published on February 12, 2004; doi:10.1074/jbc.M312597200 [Abstract] [Full Text] [PDF]

Deborah Schechtman, Madeleine L. Craske, Viktoria Kheifets, Tobias Meyer, Jack Schechtman, and Daria Mochly-Rosen: A Critical Intramolecular Interaction for Protein Kinase C ${epsilon}$ Translocation
J. Biol. Chem. 2004 279: 15831-15840. First Published on January 22, 2004; doi:10.1074/jbc.M310696200 [Abstract] [Full Text] [PDF]

Stuart Ford, Antony Antoniou, Geoffrey W. Butcher, and Simon J. Powis: Competition for Access to the Rat Major Histocompatibility Complex Class I Peptide-loading Complex Reveals Optimization of Peptide Cargo in the Absence of Transporter Associated with Antigen Processing (TAP) Association
J. Biol. Chem. 2004 279: 16077-16082. First Published on February 4, 2004; doi:10.1074/jbc.M400456200 [Abstract] [Full Text] [PDF]

Patricia E. Carrigan, Gregory M. Nelson, Patricia J. Roberts, Jha'Nae Stoffer, Daniel L. Riggs, and David F. Smith: Multiple Domains of the Co-chaperone Hop Are Important for Hsp70 Binding
J. Biol. Chem. 2004 279: 16185-16193. First Published on February 11, 2004; doi:10.1074/jbc.M314130200 [Abstract] [Full Text] [PDF]

Masaaki Taniguchi, Tatsunari Yoshimi, Kunihiro Hongo, Tomohiro Mizobata, and Yasushi Kawata: Stopped-flow Fluorescence Analysis of the Conformational Changes in the GroEL Apical Domain: RELATIONSHIPS BETWEEN MOVEMENTS IN THE APICAL DOMAIN AND THE QUATERNARY STRUCTURE OF GroEL
J. Biol. Chem. 2004 279: 16368-16376. First Published on January 20, 2004; doi:10.1074/jbc.M311806200 [Abstract] [Full Text] [PDF]

Hasige A. Sathish, Hanane A. Koteiche, and Hassane S. Mchaourab: Binding of Destabilized ${beta}$ B2-Crystallin Mutants to ${alpha}$ -Crystallin: THE ROLE OF A FOLDING INTERMEDIATE
J. Biol. Chem. 2004 279: 16425-16432. First Published on February 3, 2004; doi:10.1074/jbc.M313402200 [Abstract] [Full Text] [PDF]

Lucile Pernot, Laurent Chesnel, Audrey Le Gouellec, Jacques Croizé, Thierry Vernet, Otto Dideberg, and Andréa Dessen: A PBP2x from a Clinical Isolate of Streptococcus pneumoniae Exhibits an Alternative Mechanism for Reduction of Susceptibility to ${beta}$ -Lactam Antibiotics
J. Biol. Chem. 2004 279: 16463-16470. First Published on January 20, 2004; doi:10.1074/jbc.M313492200 [Abstract] [Full Text] [PDF]

Vickery L. Arcus, Kristina Bäckbro, Annette Roos, Emma L. Daniel, and Edward N. Baker: Distant Structural Homology Leads to the Functional Characterization of an Archaeal PIN Domain as an Exonuclease
J. Biol. Chem. 2004 279: 16471-16478. First Published on January 20, 2004; doi:10.1074/jbc.M313833200 [Abstract] [Full Text] [PDF]

Masaru Goto, Rie Omi, Ikuko Miyahara, Akira Hosono, Hiroyuki Mizuguchi, Hideyuki Hayashi, Hiroyuki Kagamiyama, and Ken Hirotsu: Crystal Structures of Glutamine:Phenylpyruvate Aminotransferase from Thermus thermophilus HB8: INDUCED FIT AND SUBSTRATE RECOGNITION
J. Biol. Chem. 2004 279: 16518-16525. First Published on February 3, 2004; doi:10.1074/jbc.M311575200 [Abstract] [Full Text] [PDF]

Julie A. Hoy, Suman Kundu, James T. Trent, III, S. Ramaswamy, and Mark S. Hargrove: The Crystal Structure of Synechocystis Hemoglobin with a Covalent Heme Linkage
J. Biol. Chem. 2004 279: 16535-16542. First Published on January 21, 2004; doi:10.1074/jbc.M313707200 [Abstract] [Full Text] [PDF]

Tali Gidalevitz, Chhanda Biswas, Hua Ding, Dina Schneidman-Duhovny, Haim J. Wolfson, Fred Stevens, Sheena Radford, and Yair Argon: Identification of the N-terminal Peptide Binding Site of Glucose-regulated Protein 94
J. Biol. Chem. 2004 279: 16543-16552. First Published on January 30, 2004; doi:10.1074/jbc.M313060200 [Abstract] [Full Text] [PDF]

Gregory J. Carven, Sriram Chitta, Ivan Hilgert, Mia M. Rushe, Rick F. Baggio, Michelle Palmer, Jaime E. Arenas, Jack L. Strominger, Vaclav Horejsi, Laura Santambrogio, and Lawrence J. Stern: Monoclonal Antibodies Specific for the Empty Conformation of HLA-DR1 Reveal Aspects of the Conformational Change Associated with Peptide Binding
J. Biol. Chem. 2004 279: 16561-16570. First Published on February 2, 2004; doi:10.1074/jbc.M314315200 [Abstract] [Full Text] [PDF]

Muthiah Kumaraswami, Martha M. Howe, and Hee-Won Park: Crystal Structure of the Mor Protein of Bacteriophage Mu, a Member of the Mor/C Family of Transcription Activators
J. Biol. Chem. 2004 279: 16581-16590. First Published on January 16, 2004; doi:10.1074/jbc.M313555200 [Abstract] [Full Text] [PDF]

Roman A. Melnyk, Sanguk Kim, A. Rachael Curran, Donald M. Engelman, James U. Bowie, and Charles M. Deber: The Affinity of GXXXG Motifs in Transmembrane Helix-Helix Interactions Is Modulated by Long-range Communication
J. Biol. Chem. 2004 279: 16591-16597. First Published on February 5, 2004; doi:10.1074/jbc.M313936200 [Abstract] [Full Text] [PDF]

Fakhri Mahdi, Zia Shariat-Madar, Alice Kuo, Maria Carinato, Douglas B. Cines, and Alvin H. Schmaier: Mapping the Interaction between High Molecular Mass Kininogen and the Urokinase Plasminogen Activator Receptor
J. Biol. Chem. 2004 279: 16621-16628. First Published on February 5, 2004; doi:10.1074/jbc.M313850200 [Abstract] [Full Text] [PDF]

Ying Guo, Xuemei Yu, Kayla Rihani, Qing-Yin Wang, and Lijun Rong: The Role of a Conserved Acidic Residue in Calcium-dependent Protein Folding for a Low Density Lipoprotein (LDL)-A Module: IMPLICATIONS IN STRUCTURE AND FUNCTION FOR THE LDL RECEPTOR SUPERFAMILY
J. Biol. Chem. 2004 279: 16629-16637. First Published on January 27, 2004; doi:10.1074/jbc.M400157200 [Abstract] [Full Text] [PDF]

Kenneth K.-S. Ng, Natalia Pendás-Franco, Jorge Rojo, José A. Boga, Àngeles Machín, José M. Martín Alonso, and Francisco Parra: Crystal Structure of Norwalk Virus Polymerase Reveals the Carboxyl Terminus in the Active Site Cleft
J. Biol. Chem. 2004 279: 16638-16645. First Published on February 5, 2004; doi:10.1074/jbc.M400584200 [Abstract] [Full Text] [PDF]

Suhkmann Kim, Ziming Zhang, Sean Upchurch, Nancy Isern, and Yuan Chen: Structure and DNA-binding Sites of the SWI1 AT-rich Interaction Domain (ARID) Suggest Determinants for Sequence-specific DNA Recognition
J. Biol. Chem. 2004 279: 16670-16676. First Published on January 13, 2004; doi:10.1074/jbc.M312115200 [Abstract] [Full Text] [PDF]

Masa Cemazar, Sotir Zahariev, Sándor Pongor, and Peter J. Hore: Oxidative Folding of Amaranthus ${alpha}$ -Amylase Inhibitor: DISULFIDE BOND FORMATION AND CONFORMATIONAL FOLDING
J. Biol. Chem. 2004 279: 16697-16705. First Published on January 28, 2004; doi:10.1074/jbc.M312328200 [Abstract] [Full Text] [PDF]

Darshana R. Patel, Heidi J. A. Wallweber, JianPing Yin, Stephanie K. Shriver, Scot A. Marsters, Nathaniel C. Gordon, Melissa A. Starovasnik, and Robert F. Kelley: Engineering an APRIL-specific B Cell Maturation Antigen
J. Biol. Chem. 2004 279: 16727-16735. First Published on February 4, 2004; doi:10.1074/jbc.M312316200 [Abstract] [Full Text] [PDF]

Rong Shi and Sheng-Xiang Lin: Cofactor Hydrogen Bonding onto the Protein Main Chain Is Conserved in the Short Chain Dehydrogenase/Reductase Family and Contributes to Nicotinamide Orientation
J. Biol. Chem. 2004 279: 16778-16785. First Published on February 13, 2004; doi:10.1074/jbc.M313156200 [Abstract] [Full Text] [PDF]

Enzyme Catalysis and Regulation:

Jotaro Igarashi, Akira Sato, Teizo Kitagawa, Tetsuhiko Yoshimura, Seigo Yamauchi, Ikuko Sagami, and Toru Shimizu: Activation of Heme-regulated Eukaryotic Initiation Factor 2 ${alpha}$ Kinase by Nitric Oxide Is Induced by the Formation of a Five-coordinate NO-Heme Complex: OPTICAL ABSORPTION, ELECTRON SPIN RESONANCE, AND RESONANCE RAMAN SPECTRAL STUDIES
J. Biol. Chem. 2004 279: 15752-15762. First Published on January 29, 2004; doi:10.1074/jbc.M310273200 [Abstract] [Full Text] [PDF]

Keiji Nogami, Kirsty A. Lapan, Qian Zhou, Hironao Wakabayashi, and Philip J. Fay: Identification of a Factor Xa-interactive Site within Residues 337–372 of the Factor VIII Heavy Chain
J. Biol. Chem. 2004 279: 15763-15771. First Published on February 4, 2004; doi:10.1074/jbc.M400568200 [Abstract] [Full Text] [PDF]

Valerie Sloane and Grover L. Waldrop: Kinetic Characterization of Mutations Found in Propionic Acidemia and Methylcrotonylglycinuria: EVIDENCE FOR COOPERATIVITY IN BIOTIN CARBOXYLASE
J. Biol. Chem. 2004 279: 15772-15778. First Published on February 11, 2004; doi:10.1074/jbc.M311982200 [Abstract] [Full Text] [PDF]

Apurba Kumar Sau, Zhili Li, and Karen S. Anderson: Probing the Role of Metal Ions in the Catalysis of Helicobacter pylori 3-Deoxy-D-manno-octulosonate-8-phosphate Synthase Using a Transient Kinetic Analysis
J. Biol. Chem. 2004 279: 15787-15794. First Published on December 30, 2003; doi:10.1074/jbc.M308989200 [Abstract] [Full Text] [PDF]

Sebastien Fuchs, Hong D. Xiao, Justin M. Cole, Jonathan W. Adams, Kristen Frenzel, Annie Michaud, Hui Zhao, George Keshelava, Mario R. Capecchi, Pierre Corvol, and Kenneth E. Bernstein: Role of the N-terminal Catalytic Domain of Angiotensin-converting Enzyme Investigated by Targeted Inactivation in Mice
J. Biol. Chem. 2004 279: 15946-15953. First Published on February 2, 2004; doi:10.1074/jbc.M400149200 [Abstract] [Full Text] [PDF]

José Angel Santamaria-Araujo, Berthold Fischer, Tanja Otte, Manfred Nimtz, Ralf R. Mendel, Victor Wray, and Günter Schwarz: The Tetrahydropyranopterin Structure of the Sulfur-free and Metal-free Molybdenum Cofactor Precursor
J. Biol. Chem. 2004 279: 15994-15999. First Published on February 3, 2004; doi:10.1074/jbc.M311815200 [Abstract] [Full Text] [PDF]

Silvia Naus, Melanie Richter, Dirk Wildeboer, Marcia Moss, Melitta Schachner, and Jörg W. Bartsch: Ectodomain Shedding of the Neural Recognition Molecule CHL1 by the Metalloprotease-disintegrin ADAM8 Promotes Neurite Outgrowth and Suppresses Neuronal Cell Death
J. Biol. Chem. 2004 279: 16083-16090. First Published on February 4, 2004; doi:10.1074/jbc.M400560200 [Abstract] [Full Text] [PDF]

Marian Fabian, Daniel Jancura, and Graham Palmer: Two Sites of Interaction of Anions with Cytochrome a in Oxidized Bovine Cytochrome c Oxidase
J. Biol. Chem. 2004 279: 16170-16177. First Published on February 6, 2004; doi:10.1074/jbc.M311834200 [Abstract] [Full Text] [PDF]

Atsuya Shimizu, Tadashi Matsushita, Takahisa Kondo, Yasuya Inden, Tetsuhito Kojima, Hidehiko Saito, and Makoto Hirai: Identification of the Amino Acid Residues of the Platelet Glycoprotein Ib (GPIb) Essential for the von Willebrand Factor Binding by Clustered Charged-to-Alanine Scanning Mutagenesis
J. Biol. Chem. 2004 279: 16285-16294. First Published on February 2, 2004; doi:10.1074/jbc.M307230200 [Abstract] [Full Text] [PDF]

Xin Chen and Barbara L. Stitt: The Binding of C₁₀ Oligomers to Escherichia coli Transcription Termination Factor Rho
J. Biol. Chem. 2004 279: 16301-16310. First Published on February 2, 2004; doi:10.1074/jbc.M313640200 [Abstract] [Full Text] [PDF]

Kevin P. Battaile, Tien V. Nguyen, Jerry Vockley, and Jung-Ja P. Kim: Structures of Isobutyryl-CoA Dehydrogenase and Enzyme-Product Complex: COMPARISON WITH ISOVALERYL- AND SHORT-CHAIN ACYL-COA DEHYDROGENASES
J. Biol. Chem. 2004 279: 16526-16534. First Published on January 28, 2004; doi:10.1074/jbc.M400034200 [Abstract] [Full Text] [PDF]

Dominique A. Glauser, Florence Bourquin, Wanda Manieri, and Peter Schürmann: Characterization of Ferredoxin:Thioredoxin Reductase Modified by Site-directed Mutagenesis
J. Biol. Chem. 2004 279: 16662-16669. First Published on February 9, 2004; doi:10.1074/jbc.M313851200 [Abstract] [Full Text] [PDF]

Vahab Ali, Yasuo Shigeta, Umechiyo Tokumoto, Yasuhiro Takahashi, and Tomoyoshi Nozaki: An Intestinal Parasitic Protist, Entamoeba histolytica, Possesses a Non-redundant Nitrogen Fixation-like System for Iron-Sulfur Cluster Assembly under Anaerobic Conditions
J. Biol. Chem. 2004 279: 16863-16874. First Published on February 2, 2004; doi:10.1074/jbc.M313314200 [Abstract] [Full Text] [PDF]

Metabolism and Bioenergetics:

Sergei A. Dikanov, Rimma I. Samoilova, Derrick R. J. Kolling, J. Todd Holland, and Antony R. Crofts: Hydrogen Bonds Involved in Binding the Q_i-site Semiquinone in the bc₁ Complex, Identified through Deuterium Exchange Using Pulsed EPR
J. Biol. Chem. 2004 279: 15814-15823. First Published on January 21, 2004; doi:10.1074/jbc.M313417200 [Abstract] [Full Text] [PDF]

Maya Kamao, Syuichiro Tatematsu, Susumi Hatakeyama, Toshiyuki Sakaki, Natsumi Sawada, Kuniyo Inouye, Keiichi Ozono, Noboru Kubodera, G. Satyanarayana Reddy, and Toshio Okano: C-3 Epimerization of Vitamin D₃ Metabolites and Further Metabolism of C-3 Epimers: 25-HYDROXYVITAMIN D₃ IS METABOLIZED TO 3-EPI-25-HYDROXYVITAMIN D₃ AND SUBSEQUENTLY METABOLIZED THROUGH C-1 ${alpha}$ OR C-24 HYDROXYLATION
J. Biol. Chem. 2004 279: 15897-15907. First Published on February 2, 2004; doi:10.1074/jbc.M311473200 [Abstract] [Full Text] [PDF]

Hanayo Ueoka-Nakanishi, Yoichi Nakanishi, Hiroki Konno, Ken Motohashi, Dirk Bald, and Toru Hisabori: Inverse Regulation of Rotation of F₁-ATPase by the Mutation at the Regulatory Region on the ${gamma}$ Subunit of Chloroplast ATP Synthase
J. Biol. Chem. 2004 279: 16272-16277. First Published on January 26, 2004; doi:10.1074/jbc.M400607200 [Abstract] [Full Text] [PDF]

Keiki Ishiyama, Eri Inoue, Akiko Watanabe-Takahashi, Mitsuhiro Obara, Tomoyuki Yamaya, and Hideki Takahashi: Kinetic Properties and Ammonium-dependent Regulation of Cytosolic Isoenzymes of Glutamine Synthetase in Arabidopsis
J. Biol. Chem. 2004 279: 16598-16605. First Published on February 2, 2004; doi:10.1074/jbc.M313710200 [Abstract] [Full Text] [PDF]

Glycobiology and Extracellular Matrices:

Carlos A. Buscaglia, Vanina A. Campo, Javier M. Di Noia, Ana C. T. Torrecilhas, Cláudia R. De Marchi, Michael A. J. Ferguson, Alberto C. C. Frasch, and Igor C. Almeida: The Surface Coat of the Mammal-dwelling Infective Trypomastigote Stage of Trypanosoma cruzi Is Formed by Highly Diverse Immunogenic Mucins
J. Biol. Chem. 2004 279: 15860-15869. First Published on January 28, 2004; doi:10.1074/jbc.M314051200 [Abstract] [Full Text] [PDF]

Lipids and Lipoproteins:

Yoshiyuki Satake, Bruno L. Diaz, Barbara Balestrieri, Bing K. Lam, Yoshihide Kanaoka, Michael J. Grusby, and Jonathan P. Arm: Role of Group V Phospholipase A₂ in Zymosan-induced Eicosanoid Generation and Vascular Permeability Revealed by Targeted Gene Disruption
J. Biol. Chem. 2004 279: 16488-16494. First Published on February 4, 2004; doi:10.1074/jbc.M313748200 [Abstract] [Full Text] [PDF]

Antonio del Castillo-Olivares, José A. Campos, William M. Pandak, and Gregorio Gil: The Role of ${alpha}$ ₁-Fetoprotein Transcription Factor/LRH-1 in Bile Acid Biosynthesis: A KNOWN NUCLEAR RECEPTOR ACTIVATOR THAT CAN ACT AS A SUPPRESSOR OF BILE ACID BIOSYNTHESIS
J. Biol. Chem. 2004 279: 16813-16821. First Published on February 6, 2004; doi:10.1074/jbc.M400646200 [Abstract] [Full Text] [PDF]

Membrane Transport, Structure, Function, and Biogenesis:

Anita Pottekat and Anant K. Menon: Subcellular Localization and Targeting of N-Acetylglucosaminyl Phosphatidylinositol De-N-acetylase, the Second Enzyme in the Glycosylphosphatidylinositol Biosynthetic Pathway
J. Biol. Chem. 2004 279: 15743-15751. First Published on January 23, 2004; doi:10.1074/jbc.M313537200 [Abstract] [Full Text] [PDF]

David Meredith: Site-directed Mutation of Arginine 282 to Glutamate Uncouples the Movement of Peptides and Protons by the Rabbit Proton-peptide Cotransporter PepT1
J. Biol. Chem. 2004 279: 15795-15798. First Published on January 10, 2004; doi:10.1074/jbc.M313922200 [Abstract] [Full Text] [PDF]

Anja Pernille Einholm, Bente Vilsen, and Jens Peter Andersen: Importance of Transmembrane Segment M1 of the Sarcoplasmic Reticulum Ca²+-ATPase in Ca²+ Occlusion and Phosphoenzyme Processing
J. Biol. Chem. 2004 279: 15888-15896. First Published on January 30, 2004; doi:10.1074/jbc.M400158200 [Abstract] [Full Text] [PDF]

Michael W. Quick, Jia Hu, Dan Wang, and Huai-Yu Zhang: Regulation of a ${gamma}$ -Aminobutyric Acid Transporter by Reciprocal Tyrosine and Serine Phosphorylation
J. Biol. Chem. 2004 279: 15961-15967. First Published on February 3, 2004; doi:10.1074/jbc.M306924200 [Abstract] [Full Text] [PDF]

Naziha Bakouh, Fatine Benjelloun, Philippe Hulin, Franck Brouillard, Aleksander Edelman, Baya Chérif-Zahar, and Gabrielle Planelles: NH₃ Is Involved in the NH₄ Transport Induced by the Functional Expression of the Human Rh C Glycoprotein
J. Biol. Chem. 2004 279: 15975-15983. First Published on February 3, 2004; doi:10.1074/jbc.M308528200 [Abstract] [Full Text] [PDF]

Abraham J. K. Koo, John B. Ohlrogge, and Mike Pollard: On the Export of Fatty Acids from the Chloroplast
J. Biol. Chem. 2004 279: 16101-16110. First Published on February 5, 2004; doi:10.1074/jbc.M311305200 [Abstract] [Full Text] [PDF]

Christopher T. Wagner, Irene Y. Lu, Michael H. Hoffman, Wendell Q. Sun, Jonathan D. Trent, and Jerome Connor: T-complex Polypeptide-1 Interacts with the Erythrocyte Cytoskeleton in Response to Elevated Temperatures
J. Biol. Chem. 2004 279: 16223-16228. First Published on January 18, 2004; doi:10.1074/jbc.M310730200 [Abstract] [Full Text] [PDF] Supplemental Data

Robert Augustin, Mary O. Carayannopoulos, Lia O. Dowd, John E. Phay, Jeffrey F. Moley, and Kelle H. Moley: Identification and Characterization of Human Glucose Transporter-like Protein-9 (GLUT9): ALTERNATIVE SPLICING ALTERS TRAFFICKING
J. Biol. Chem. 2004 279: 16229-16236. First Published on January 22, 2004; doi:10.1074/jbc.M312226200 [Abstract] [Full Text] [PDF]

Jemima J. Burden, Xi-Ming Sun, Ana Bárbara García García, and Anne K. Soutar: Sorting Motifs in the Intracellular Domain of the Low Density Lipoprotein Receptor Interact with a Novel Domain of Sorting Nexin-17
J. Biol. Chem. 2004 279: 16237-16245. First Published on January 22, 2004; doi:10.1074/jbc.M313689200 [Abstract] [Full Text] [PDF]

Syed M. Noorwez, Ritu Malhotra, J. Hugh McDowell, Karen A. Smith, Mark P. Krebs, and Shalesh Kaushal: Retinoids Assist the Cellular Folding of the Autosomal Dominant Retinitis Pigmentosa Opsin Mutant P23H
J. Biol. Chem. 2004 279: 16278-16284. First Published on February 9, 2004; doi:10.1074/jbc.M312101200 [Abstract] [Full Text] [PDF]

An-Qiang Sun, Natarajan Balasubramaniyan, Chuan-Ju Liu, Mohammad Shahid, and Frederick J. Suchy: Association of the 16-kDa Subunit c of Vacuolar Proton Pump with the Ileal Na⁺-dependent Bile Acid Transporter: PROTEIN-PROTEIN INTERACTION AND INTRACELLULAR TRAFFICKING
J. Biol. Chem. 2004 279: 16295-16300. First Published on January 29, 2004; doi:10.1074/jbc.M312838200 [Abstract] [Full Text] [PDF]

Alex Perálvarez-Marín, Mercedes Márquez, José-Luis Bourdelande, Enric Querol, and Esteve Padrós: Thr-90 Plays a Vital Role in the Structure and Function of Bacteriorhodopsin
J. Biol. Chem. 2004 279: 16403-16409. First Published on February 2, 2004; doi:10.1074/jbc.M313988200 [Abstract] [Full Text] [PDF]

Richard Law, Sandy Harper, David W. Speicher, and Dennis E. Discher: Influence of Lateral Association on Forced Unfolding of Antiparallel Spectrin Heterodimers
J. Biol. Chem. 2004 279: 16410-16416. First Published on February 3, 2004; doi:10.1074/jbc.M313107200 [Abstract] [Full Text] [PDF]

Jan B. Koenderink, Herman G. P. Swarts, Peter H. G. M. Willems, Elmar Krieger, and Jan Joep H. H. M. De Pont: A Conformation-specific Interhelical Salt Bridge in the K⁺ Binding Site of Gastric H,K-ATPase
J. Biol. Chem. 2004 279: 16417-16424. First Published on February 3, 2004; doi:10.1074/jbc.M400020200 [Abstract] [Full Text] [PDF]

Erika Moreno, Claudia Tovar-Palacio, Paola de los Heros, Blanca Guzmán, Norma A. Bobadilla, Norma Vázquez, Daniela Riccardi, Esteban Poch, and Gerardo Gamba: A Single Nucleotide Polymorphism Alters the Activity of the Renal Na⁺:Cl^- Cotransporter and Reveals a Role for Transmembrane Segment 4 in Chloride and Thiazide Affinity
J. Biol. Chem. 2004 279: 16553-16560. First Published on February 5, 2004; doi:10.1074/jbc.M400602200 [Abstract] [Full Text] [PDF]

Vincenzo Macri and Eric A. Accili: Structural Elements of Instantaneous and Slow Gating in Hyperpolarization-activated Cyclic Nucleotide-gated Channels
J. Biol. Chem. 2004 279: 16832-16846. First Published on January 29, 2004; doi:10.1074/jbc.M400518200 [Abstract] [Full Text] [PDF]

Mechanisms Of Signal Transduction:

Pelin Kelicen and Niclas Tindberg: Lipopolysaccharide Induces CYP2E1 in Astrocytes through MAP Kinase Kinase-3 and C/EBP ${beta}$ and - ${delta}$
J. Biol. Chem. 2004 279: 15734-15742. First Published on December 11, 2003; doi:10.1074/jbc.M311850200 [Abstract] [Full Text] [PDF]

Autumn Massiello, Arelis Salas, Ryan L. Pinkerman, Patrick Roddy, James R. Roesser, and Charles E. Chalfant: Identification of Two RNA cis-Elements That Function to Regulate the 5' Splice Site Selection of Bcl-x Pre-mRNA in Response to Ceramide
J. Biol. Chem. 2004 279: 15799-15804. First Published on January 20, 2004; doi:10.1074/jbc.M313950200 [Abstract] [Full Text] [PDF]

Nieves Ibarrola, Henrik Molina, Akiko Iwahori, and Akhilesh Pandey: A Novel Proteomic Approach for Specific Identification of Tyrosine Kinase Substrates Using [¹³C]Tyrosine
J. Biol. Chem. 2004 279: 15805-15813. First Published on January 21, 2004; doi:10.1074/jbc.M311714200 [Abstract] [Full Text] [PDF]

Jianfeng Liu, Damien Maurel, Sébastien Etzol, Isabelle Brabet, Hervé Ansanay, Jean-Philippe Pin, and Philippe Rondard: Molecular Determinants Involved in the Allosteric Control of Agonist Affinity in the GABA_B Receptor by the GABA_B2 Subunit
J. Biol. Chem. 2004 279: 15824-15830. First Published on January 21, 2004; doi:10.1074/jbc.M313639200 [Abstract] [Full Text] [PDF]

Vincent O'Connor, Alexis Genin, Sabrina Davis, K. K. Karishma, Valerie Doyère, Chris I. De Zeeuw, Gareth Sanger, Stephen P. Hunt, Gal Richter-Levin, Jacques Mallet, Serge Laroche, T. V. P. Bliss, and Pim J. French: Differential Amplification of Intron-containing Transcripts Reveals Long Term Potentiation-associated Up-regulation of Specific Pde10A Phosphodiesterase Splice Variants
J. Biol. Chem. 2004 279: 15841-15849. First Published on January 28, 2004; doi:10.1074/jbc.M312500200 [Abstract] [Full Text] [PDF]

Bernd Kreikemeyer, Sonja Oehmcke, Masanobu Nakata, Raimund Hoffrogge, and Andreas Podbielski: Streptococcus pyogenes Fibronectin-binding Protein F2: EXPRESSION PROFILE, BINDING CHARACTERISTICS, AND IMPACT ON EUKARYOTIC CELL INTERACTIONS
J. Biol. Chem. 2004 279: 15850-15859. First Published on January 28, 2004; doi:10.1074/jbc.M313613200 [Abstract] [Full Text] [PDF]

Tuanjie Che, Yun You, Donghai Wang, Matthew J. Tanner, Vishva M. Dixit, and Xin Lin: MALT1/Paracaspase Is a Signaling Component Downstream of CARMA1 and Mediates T Cell Receptor-induced NF- ${kappa}$ B Activation
J. Biol. Chem. 2004 279: 15870-15876. First Published on January 30, 2004; doi:10.1074/jbc.M310599200 [Abstract] [Full Text] [PDF]

Cora Weigert, Katrin Brodbeck, Michèle Sawadogo, Hans U. Häring, and Erwin D. Schleicher: Upstream Stimulatory Factor (USF) Proteins Induce Human TGF- ${beta}$ 1 Gene Activation via the Glucose-response Element–1013/–1002 in Mesangial Cells: UP-REGULATION OF USF ACTIVITY BY THE HEXOSAMINE BIOSYNTHETIC PATHWAY
J. Biol. Chem. 2004 279: 15908-15915. First Published on February 2, 2004; doi:10.1074/jbc.M313524200 [Abstract] [Full Text] [PDF]

Guibin Li, Haishan Yin, and Jeff Kuret: Casein Kinase 1 Delta Phosphorylates Tau and Disrupts Its Binding to Microtubules
J. Biol. Chem. 2004 279: 15938-15945. First Published on February 2, 2004; doi:10.1074/jbc.M314116200 [Abstract] [Full Text] [PDF]

Bo Xu, Ashish Bhattacharjee, Biswajit Roy, Gerald M. Feldman, and Martha K. Cathcart: Role of Protein Kinase C Isoforms in the Regulation of Interleukin-13-induced 15-Lipoxygenase Gene Expression in Human Monocytes
J. Biol. Chem. 2004 279: 15954-15960. First Published on February 2, 2004; doi:10.1074/jbc.M400413200 [Abstract] [Full Text] [PDF]

Shujuan Gao, Jun Chen, Sergey V. Brodsky, Harer Huang, Stephen Adler, Juliane H. Lee, Neetu Dhadwal, Leona Cohen-Gould, Steven S. Gross, and Michael S. Goligorsky: Docking of Endothelial Nitric Oxide Synthase (eNOS) to the Mitochondrial Outer Membrane: A PENTABASIC AMINO ACID SEQUENCE IN THE AUTOINHIBITORY DOMAIN OF eNOS TARGETS A PROTEINASE K-CLEAVABLE PEPTIDE ON THE CYTOPLASMIC FACE OF MITOCHONDRIA
J. Biol. Chem. 2004 279: 15968-15974. First Published on February 3, 2004; doi:10.1074/jbc.M308504200 [Abstract] [Full Text] [PDF]

Rive Sarfstein, Yara Gorzalczany, Ariel Mizrahi, Yevgeny Berdichevsky, Shahar Molshanski-Mor, Carolyn Weinbaum, Miriam Hirshberg, Marie-Claire Dagher, and Edgar Pick: Dual Role of Rac in the Assembly of NADPH Oxidase, Tethering to the Membrane and Activation of p67^phox: A STUDY BASED ON MUTAGENESIS OF p67^phox-Rac1 CHIMERAS
J. Biol. Chem. 2004 279: 16007-16016. First Published on February 3, 2004; doi:10.1074/jbc.M312394200 [Abstract] [Full Text] [PDF]

Claudia Hoffmann, Marius Pop, Jost Leemhuis, Jörg Schirmer, Klaus Aktories, and Gudula Schmidt: The Yersinia pseudotuberculosis Cytotoxic Necrotizing Factor (CNF_Y) Selectively Activates RhoA
J. Biol. Chem. 2004 279: 16026-16032. First Published on February 3, 2004; doi:10.1074/jbc.M313556200 [Abstract] [Full Text] [PDF]

Dyke P. McEwen, Laurence S. Meadows, Chunling Chen, Veena Thyagarajan, and Lori L. Isom: Sodium Channel ${beta}$ 1 Subunit-mediated Modulation of Na_v1.2 Currents and Cell Surface Density Is Dependent on Interactions with Contactin and Ankyrin
J. Biol. Chem. 2004 279: 16044-16049. First Published on February 3, 2004; doi:10.1074/jbc.M400856200 [Abstract] [Full Text] [PDF]

Sayeon Cho, Hyung-Mun Ko, Jeong-Min Kim, Jung-A Lee, Jae-Eun Park, Mi-Sun Jang, Sung Goo Park, Do Hee Lee, Seong-Eon Ryu, and Byoung-Chul Park: Positive Regulation of Apoptosis Signal-regulating Kinase 1 by hD53L1
J. Biol. Chem. 2004 279: 16050-16056. First Published on February 4, 2004; doi:10.1074/jbc.M305758200 [Abstract] [Full Text] [PDF]

Sharon L. Chinault, Mark C. Overton, and Kendall J. Blumer: Subunits of a Yeast Oligomeric G Protein-coupled Receptor Are Activated Independently by Agonist but Function in Concert to Activate G Protein Heterotrimers
J. Biol. Chem. 2004 279: 16091-16100. First Published on February 5, 2004; doi:10.1074/jbc.M311099200 [Abstract] [Full Text] [PDF]

Nicola Zambrano, Davide Gianni, Paola Bruni, Fabiana Passaro, Francesca Telese, and Tommaso Russo: Fe65 Is Not Involved in the Platelet-derived Growth Factor-induced Processing of Alzheimer's Amyloid Precursor Protein, Which Activates Its Caspase-directed Cleavage
J. Biol. Chem. 2004 279: 16161-16169. First Published on February 6, 2004; doi:10.1074/jbc.M311027200 [Abstract] [Full Text] [PDF]

Lorena Sánchez-Martín, Noelia Sánchez-Sánchez, M. Dolores Gutiérrez-López, Ana I. Rojo, Miguel Vicente-Manzanares, María José Pérez-Alvarez, Paloma Sánchez-Mateos, Xosé R. Bustelo, Antonio Cuadrado, Francisco Sánchez-Madrid, José Luis Rodríguez-Fernández, and Carlos Cabañas: Signaling through the Leukocyte Integrin LFA-1 in T Cells Induces a Transient Activation of Rac-1 That Is Regulated by Vav and PI3K/Akt-1
J. Biol. Chem. 2004 279: 16194-16205. First Published on February 11, 2004; doi:10.1074/jbc.M400905200 [Abstract] [Full Text] [PDF]

Stephanie L. Mackey and Gretchen J. Darlington: CCAAT Enhancer-binding Protein ${alpha}$ Is Required for Interleukin-6 Receptor ${alpha}$ Signaling in Newborn Hepatocytes
J. Biol. Chem. 2004 279: 16206-16213. First Published on February 11, 2004; doi:10.1074/jbc.M400737200 [Abstract] [Full Text] [PDF]

Jie Cui, Scot J. Matkovich, Nikhil deSouza, Suzhao Li, Nora Rosemblit, and Andrew R. Marks: Regulation of the Type 1 Inositol 1,4,5-Trisphosphate Receptor by Phosphorylation at Tyrosine 353
J. Biol. Chem. 2004 279: 16311-16316. First Published on February 3, 2004; doi:10.1074/jbc.M400206200 [Abstract] [Full Text] [PDF]

Shama Ahmad, Aftab Ahmad, Moumita Ghosh, Christina C. Leslie, and Carl W. White: Extracellular ATP-mediated Signaling for Survival in Hyperoxia-induced Oxidative Stress
J. Biol. Chem. 2004 279: 16317-16325. First Published on February 3, 2004; doi:10.1074/jbc.M313890200 [Abstract] [Full Text] [PDF]

Jacqueline A. Walisser, Maureen K. Bunger, Edward Glover, Eric B. Harstad, and Christopher A. Bradfield: Patent Ductus Venosus and Dioxin Resistance in Mice Harboring a Hypomorphic Arnt Allele
J. Biol. Chem. 2004 279: 16326-16331. First Published on February 5, 2004; doi:10.1074/jbc.M400784200 [Abstract] [Full Text] [PDF]

Hye Young Lee, Jong Bae Park, Il Ho Jang, Young Chan Chae, Jong Hyun Kim, Il Shin Kim, Pann-Ghill Suh, and Sung Ho Ryu: Munc-18-1 Inhibits Phospholipase D Activity by Direct Interaction in an Epidermal Growth Factor-reversible Manner
J. Biol. Chem. 2004 279: 16339-16348. First Published on January 26, 2004; doi:10.1074/jbc.M310976200 [Abstract] [Full Text] [PDF] Supplemental Data

Yona Goldshmit, Claire E. Walters, Hannah J. Scott, Christopher J. Greenhalgh, and Ann M. Turnley: SOCS2 Induces Neurite Outgrowth by Regulation of Epidermal Growth Factor Receptor Activation
J. Biol. Chem. 2004 279: 16349-16355. First Published on February 4, 2004; doi:10.1074/jbc.M312873200 [Abstract] [Full Text] [PDF]

László J. Kárai, James T. Russell, Michael J. Iadarola, and Zoltan Oláh: Vanilloid Receptor 1 Regulates Multiple Calcium Compartments and Contributes to Ca²⁺-induced Ca²⁺ Release in Sensory Neurons
J. Biol. Chem. 2004 279: 16377-16387. First Published on February 12, 2004; doi:10.1074/jbc.M310891200 [Abstract] [Full Text] [PDF]

Mark W. Feinberg, Masafumi Watanabe, Maria A. Lebedeva, Ana S. Depina, Jun-ichi Hanai, Tadanori Mammoto, Joshua P. Frederick, Xiao-Fan Wang, Vikas P. Sukhatme, and Mukesh K. Jain: Transforming Growth Factor- ${beta}$ 1 Inhibition of Vascular Smooth Muscle Cell Activation Is Mediated via Smad3
J. Biol. Chem. 2004 279: 16388-16393. First Published on February 1, 2004; doi:10.1074/jbc.M309664200 [Abstract] [Full Text] [PDF]

Jee-Yin Ahn, Rong Rong, Todd G. Kroll, Erwin G. Van Meir, Solomon H. Snyder, and Keqiang Ye: PIKE (Phosphatidylinositol 3-Kinase Enhancer)-A GTPase Stimulates Akt Activity and Mediates Cellular Invasion
J. Biol. Chem. 2004 279: 16441-16451. First Published on February 3, 2004; doi:10.1074/jbc.M312175200 [Abstract] [Full Text] [PDF]

Jiangong Niu, Zhongkui Li, Bailu Peng, and Paul J. Chiao: Identification of an Autoregulatory Feedback Pathway Involving Interleukin-1 ${alpha}$ in Induction of Constitutive NF- ${kappa}$ B Activation in Pancreatic Cancer Cells
J. Biol. Chem. 2004 279: 16452-16462. First Published on December 16, 2003; doi:10.1074/jbc.M309789200 [Abstract] [Full Text] [PDF]

Patricia Rouet-Benzineb, Thomas Aparicio, Sandra Guilmeau, Cécile Pouzet, Véronique Descatoire, Marion Buyse, and André Bado: Leptin Counteracts Sodium Butyrate-induced Apoptosis in Human Colon Cancer HT-29 Cells via NF- ${kappa}$ B Signaling
J. Biol. Chem. 2004 279: 16495-16502. First Published on January 29, 2004; doi:10.1074/jbc.M312999200 [Abstract] [Full Text] [PDF]

Miho Iijima, Yi Elaine Huang, Hongbo R. Luo, Francisca Vazquez, and Peter N. Devreotes: Novel Mechanism of PTEN Regulation by Its Phosphatidylinositol 4,5-Bisphosphate Binding Motif Is Critical for Chemotaxis
J. Biol. Chem. 2004 279: 16606-16613. First Published on February 5, 2004; doi:10.1074/jbc.M312098200 [Abstract] [Full Text] [PDF]

Gurpreet K. Dhami, Lianne B. Dale, Pieter H. Anborgh, Katharine E. O'Connor-Halligan, Rachel Sterne-Marr, and Stephen S. G. Ferguson: G Protein-coupled Receptor Kinase 2 Regulator of G Protein Signaling Homology Domain Binds to Both Metabotropic Glutamate Receptor 1a and G ${alpha}$ _q to Attenuate Signaling
J. Biol. Chem. 2004 279: 16614-16620. First Published on February 4, 2004; doi:10.1074/jbc.M314090200 [Abstract] [Full Text] [PDF]

Jennifer J. Gentry, Nancy J. Rutkoski, Tara L. Burke, and Bruce D. Carter: A Functional Interaction between the p75 Neurotrophin Receptor Interacting Factors, TRAF6 and NRIF
J. Biol. Chem. 2004 279: 16646-16656. First Published on February 11, 2004; doi:10.1074/jbc.M309209200 [Abstract] [Full Text] [PDF]

Fangtian Huang, Anastasia Khvorova, William Marshall, and Alexander Sorkin: Analysis of Clathrin-mediated Endocytosis of Epidermal Growth Factor Receptor by RNA Interference
J. Biol. Chem. 2004 279: 16657-16661. First Published on February 25, 2004; doi:10.1074/jbc.C400046200 [Abstract] [Full Text] [PDF] Supplemental Data

Teruaki Nomura, Jun Tanikawa, Hiroshi Akimaru, Chie Kanei-Ishii, Emi Ichikawa-Iwata, Md Matiullah Khan, Hiroki Ito, and Shunsuke Ishii: Oncogenic Activation of c-Myb Correlates with a Loss of Negative Regulation by TIF1 ${beta}$ and Ski
J. Biol. Chem. 2004 279: 16715-16726. First Published on February 3, 2004; doi:10.1074/jbc.M313069200 [Abstract] [Full Text] [PDF] Supplemental Data

Harrold A. van den Burg, Christian A. E. M. Spronk, Sjef Boeren, Matthew A. Kennedy, Johannes P. C. Vissers, Geerten W. Vuister, Pierre J. G. M. de Wit, and Jacques Vervoort: Binding of the AVR4 Elicitor of Cladosporium fulvum to Chitotriose Units Is Facilitated by Positive Allosteric Protein-Protein Interactions: THE CHITIN-BINDING SITE OF AVR4 REPRESENTS A NOVEL BINDING SITE ON THE FOLDING SCAFFOLD SHARED BETWEEN THE INVERTEBRATE AND THE PLANT CHITIN-BINDING DOMAIN
J. Biol. Chem. 2004 279: 16786-16796. First Published on February 9, 2004; doi:10.1074/jbc.M312594200 [Abstract] [Full Text] [PDF] Supplemental Data

Jun Huang, Lin Teng, Lixia Li, Ting Liu, Lianyun Li, Danying Chen, Liang-Guo Xu, Zhonghe Zhai, and Hong-Bing Shu: ZNF216 Is an A20-like and I ${kappa}$ B Kinase ${gamma}$ -Interacting Inhibitor of NF ${kappa}$ B Activation
J. Biol. Chem. 2004 279: 16847-16853. First Published on January 30, 2004; doi:10.1074/jbc.M309491200 [Abstract] [Full Text] [PDF]

James Sinnett-Smith, Elena Zhukova, Nena Hsieh, Xiaohua Jiang, and Enrique Rozengurt: Protein Kinase D Potentiates DNA Synthesis Induced by G_q-coupled Receptors by Increasing the Duration of ERK Signaling in Swiss 3T3 Cells
J. Biol. Chem. 2004 279: 16883-16893. First Published on February 12, 2004; doi:10.1074/jbc.M313225200 [Abstract] [Full Text] [PDF]

Molecular Basis Of Cell and Developmental Biology:

Wayne L. Davies, Jamie I. Vandenberg, Rana A. Sayeed, and Ann E. O. Trezise: Cardiac Expression of the Cystic Fibrosis Transmembrane Conductance Regulator Involves Novel Exon 1 Usage to Produce a Unique Amino-terminal Protein
J. Biol. Chem. 2004 279: 15877-15887. First Published on January 30, 2004; doi:10.1074/jbc.M313628200 [Abstract] [Full Text] [PDF] Suppplemental Data

Jiliang Zhou, April M. Hoggatt, and B. Paul Herring: Activation of the Smooth Muscle-specific Telokin Gene by Thyrotroph Embryonic Factor (TEF)
J. Biol. Chem. 2004 279: 15929-15937. First Published on January 26, 2004; doi:10.1074/jbc.M313822200 [Abstract] [Full Text] [PDF]

Svetoslava D. Stamenova, Rebecca Dunn, Adam S. Adler, and Linda Hicke: The Rsp5 Ubiquitin Ligase Binds to and Ubiquitinates Members of the Yeast CIN85-Endophilin Complex, Sla1-Rvs167
J. Biol. Chem. 2004 279: 16017-16025. First Published on February 3, 2004; doi:10.1074/jbc.M313479200 [Abstract] [Full Text] [PDF]

Kenneth J. Mandell, Ingrid C. McCall, and Charles A. Parkos: Involvement of the Junctional Adhesion Molecule-1 (JAM1) Homodimer Interface in Regulation of Epithelial Barrier Function
J. Biol. Chem. 2004 279: 16254-16262. First Published on January 28, 2004; doi:10.1074/jbc.M309483200 [Abstract] [Full Text] [PDF]

Pu Qin, Juliet M. Haberbusch, Zhenping Zhang, Kenneth J. Soprano, and Dianne R. Soprano: Pre-B Cell Leukemia Transcription Factor (PBX) Proteins Are Important Mediators for Retinoic Acid-dependent Endodermal and Neuronal Differentiation of Mouse Embryonal Carcinoma P19 Cells
J. Biol. Chem. 2004 279: 16263-16271. First Published on January 23, 2004; doi:10.1074/jbc.M313938200 [Abstract] [Full Text] [PDF]

Anna Di Carlo, Roberta De Mori, Fabio Martelli, Giulio Pompilio, Maurizio C. Capogrossi, and Antonia Germani: Hypoxia Inhibits Myogenic Differentiation through Accelerated MyoD Degradation
J. Biol. Chem. 2004 279: 16332-16338. First Published on February 1, 2004; doi:10.1074/jbc.M313931200 [Abstract] [Full Text] [PDF]

Tomoya Nakatani, Eri Mizuhara, Yasuko Minaki, Yoshimasa Sakamoto, and Yuichi Ono: Helt, a Novel Basic-Helix-Loop-Helix Transcriptional Repressor Expressed in the Developing Central Nervous System
J. Biol. Chem. 2004 279: 16356-16367. First Published on February 4, 2004; doi:10.1074/jbc.M311740200 [Abstract] [Full Text] [PDF]

Reiko Ban, Yasuhiro Irino, Kiyoko Fukami, and Hirofumi Tanaka: Human Mitotic Spindle-associated Protein PRC1 Inhibits MgcRacGAP Activity toward Cdc42 during the Metaphase
J. Biol. Chem. 2004 279: 16394-16402. First Published on January 26, 2004; doi:10.1074/jbc.M313257200 [Abstract] [Full Text] [PDF]

Krishnakumar Kizhatil and Vann Bennett: Lateral Membrane Biogenesis in Human Bronchial Epithelial Cells Requires 190-kDa Ankyrin-G
J. Biol. Chem. 2004 279: 16706-16714. First Published on February 1, 2004; doi:10.1074/jbc.M314296200 [Abstract] [Full Text] [PDF] Supplemental Data

Dibyendu K. Panda, Dengshun Miao, Isabel Bolivar, Jiarong Li, Rujuan Huo, Geoffrey N. Hendy, and David Goltzman: Inactivation of the 25-Hydroxyvitamin D 1 ${alpha}$ -Hydroxylase and Vitamin D Receptor Demonstrates Independent and Interdependent Effects of Calcium and Vitamin D on Skeletal and Mineral Homeostasis
J. Biol. Chem. 2004 279: 16754-16766. First Published on January 22, 2004; doi:10.1074/jbc.M310271200 [Abstract] [Full Text] [PDF]

Yuichi Hashimoto, Osahiko Tsuji, Kohsuke Kanekura, Sadakazu Aiso, Takako Niikura, Masaaki Matsuoka, and Ikuo Nishimoto: The Gtx Homeodomain Transcription Factor Exerts Neuroprotection Using Its Homeodomain
J. Biol. Chem. 2004 279: 16767-16777. First Published on January 29, 2004; doi:10.1074/jbc.M313630200 [Abstract] [Full Text] [PDF]

M. Reza Saadatzadeh, Khadijeh Bijangi-Vishehsaraei, Ping Hong, Heidi Bergmann, and Laura S. Haneline: Oxidant Hypersensitivity of Fanconi Anemia Type C-deficient Cells Is Dependent on a Redox-regulated Apoptotic Pathway
J. Biol. Chem. 2004 279: 16805-16812. First Published on February 5, 2004; doi:10.1074/jbc.M313721200 [Abstract] [Full Text] [PDF]

Additions and Corrections:

Yu-Chi Chiang, Shu-Chun Teng, Yi-Ning Su, Fon-Jou Hsieh, and Kou-Juey Wu: c-Myc directly regulates the transcription of the NBS1 gene involved in DNA double-strand break repair. Vol. 278 (2003) 19286-19291
J. Biol. Chem. 2004 279: 16894. [Full Text] [PDF]

Tatiana A. Chernova, Kim D. Allen, Lisa M. Wesoloski, John R. Shanks, Yury O. Chernoff, and Keith D. Wilkinson: Pleiotropic effects of Ubp6 loss on drug sensitivities and yeast prion are due to depletion of free ubiquitin pool. Vol. 278 (2003) 52102-52115
J. Biol. Chem. 2004 279: 16894-a. [Full Text]