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Table of Contents: Oct 8 2004; 279 (41)   [Index by Author]  [Papers Of The Week] [Cover Figure and Caption]
       Papers Of The Week
       Classics
       Minireviews
       Accelerated Publications
       DNA: Replication, Repair, and Recombination
       Genes: Structure and Regulation
       Protein Synthesis, Post-Translation Modification, and Degradation
       Protein Structure and Folding
       Enzyme Catalysis and Regulation
       Metabolism and Bioenergetics
       Glycobiology and Extracellular Matrices
       Lipids and Lipoproteins
       Membrane Transport, Structure, Function, and Biogenesis
       Mechanisms Of Signal Transduction
       Molecular Basis Of Cell and Developmental Biology
       Additions and Corrections
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Papers Of The Week:


CA Repeats in the 3'-Untranslated Region of bcl-2 mRNA Mediate Constitutive Decay of bcl-2 mRNA

J. Biol. Chem. 2004 279: e99914. [Full Text] [PDF]  


Structural Insights into the Catalytic Mechanism of Phosphate Ester Hydrolysis by dUTPase

J. Biol. Chem. 2004 279: e99915. [Full Text] [PDF]  


Classics:

Nicole Kresge, Robert D. Simoni, and Robert L. Hill
The Discovery of Avidin by Esmond E. Snell
A CONSTITUENT OF RAW EGG WHITE CAPABLE OF INACTIVATING BIOTIN IN VITRO (Robert E. Eakin, Esmond E. Snell, and Roger J. Williams J. Biol. Chem. 136, 801-802)
THE CONCENTRATION AND ASSAY OF AVIDIN, THE INJURY-PRODUCING PROTEIN IN RAW EGG WHITE (Robert E. Eakin, Esmond E. Snell, and Roger J. Williams J. Biol. Chem. 140, 535-543)
J. Biol. Chem. 2004 279: e5. [Full Text]  


Minireviews:

R. Paul Robertson
Chronic Oxidative Stress as a Central Mechanism for Glucose Toxicity in Pancreatic Islet Beta Cells in Diabetes
J. Biol. Chem. 2004 279: 42351-42354. First Published on July 16, 2004; doi:10.1074/jbc.R400019200 [Full Text] [PDF]  


Accelerated Publications:

Katarina Holmborn, Johan Ledin, Emanuel Smeds, Inger Eriksson, Marion Kusche-Gullberg, and Lena Kjellén
Heparan Sulfate Synthesized by Mouse Embryonic Stem Cells Deficient in NDST1 and NDST2 Is 6-O-Sulfated but Contains No N-Sulfate Groups
J. Biol. Chem. 2004 279: 42355-42358. First Published on August 19, 2004; doi:10.1074/jbc.C400373200 [Abstract] [Full Text] [PDF]  

Songon An and Karin Musier-Forsyth
Trans-editing of Cys-tRNAPro by Haemophilus influenzae YbaK Protein
J. Biol. Chem. 2004 279: 42359-42362. First Published on August 20, 2004; doi:10.1074/jbc.C400304200 [Abstract] [Full Text] [PDF]  


DNA: Replication, Repair, and Recombination:

Jie Lin Liu, Pascal Rigolet, Shuo-Xing Dou, Peng-Ye Wang, and Xu Guang Xi
The Zinc Finger Motif of Escherichia coli RecQ Is Implicated in Both DNA Binding and Protein Folding
J. Biol. Chem. 2004 279: 42794-42802. First Published on July 29, 2004; doi:10.1074/jbc.M405008200 [Abstract] [Full Text] [PDF]  

Daniele Arosio, Silvia Costantini, Yong Kong, and Alessandro Vindigni
Fluorescence Anisotropy Studies on the Ku-DNA Interaction: ANION AND CATION EFFECTS
J. Biol. Chem. 2004 279: 42826-42835. First Published on July 28, 2004; doi:10.1074/jbc.M406529200 [Abstract] [Full Text] [PDF]  

Mariarita De Felice, Luca Esposito, Biagio Pucci, Mariarosaria De Falco, Mosè Rossi, and Francesca M. Pisani
A CDC6-like Factor from the Archaea Sulfolobus solfataricus Promotes Binding of the Mini-chromosome Maintenance Complex to DNA
J. Biol. Chem. 2004 279: 43008-43012. First Published on July 29, 2004; doi:10.1074/jbc.M406693200 [Abstract] [Full Text] [PDF]  


Genes: Structure and Regulation:

Dimitar Angelov, François Lenouvel, Fabienne Hans, Christoph W. Müller, Philippe Bouvet, Jan Bednar, Evangelos N. Moudrianakis, Jean Cadet, and Stefan Dimitrov
The Histone Octamer Is Invisible When NF-{kappa}B Binds to the Nucleosome
J. Biol. Chem. 2004 279: 42374-42382. First Published on July 21, 2004; doi:10.1074/jbc.M407235200 [Abstract] [Full Text] [PDF]  

Gang Zheng and Yu-Chung Yang
ZNF76, a Novel Transcriptional Repressor Targeting TATA-binding Protein, Is Modulated by Sumoylation
J. Biol. Chem. 2004 279: 42410-42421. First Published on July 26, 2004; doi:10.1074/jbc.M407287200 [Abstract] [Full Text] [PDF]  

Kashelle Lockman, Jeremiah S. Hinson, Matt D. Medlin, Dionne Morris, Joan M. Taylor, and Christopher P. Mack
Sphingosine 1-Phosphate Stimulates Smooth Muscle Cell Differentiation and Proliferation by Activating Separate Serum Response Factor Co-factors
J. Biol. Chem. 2004 279: 42422-42430. First Published on August 3, 2004; doi:10.1074/jbc.M405432200 [Abstract] [Full Text] [PDF]  

Nicholas J. Koszewski, Alexander P. Alimov, Ok-Kyong Park-Sarge, and Hartmut H. Malluche
Suppression of the Human Parathyroid Hormone Promoter by Vitamin D Involves Displacement of NF-Y Binding to the Vitamin D Response Element
J. Biol. Chem. 2004 279: 42431-42437. First Published on August 5, 2004; doi:10.1074/jbc.M407742200 [Abstract] [Full Text] [PDF]  

Weizhong Chang, Amar Rewari, Michael Centrella, and Thomas L. McCarthy
Fos-related Antigen 2 Controls Protein Kinase A-induced CCAAT/Enhancer-binding Protein {beta} Expression in Osteoblasts
J. Biol. Chem. 2004 279: 42438-42444. First Published on August 6, 2004; doi:10.1074/jbc.M405549200 [Abstract] [Full Text] [PDF]  

Shi Lei, Alexander Dubeykovskiy, Abhijit Chakladar, Lindsay Wojtukiewicz, and Timothy C. Wang
The Murine Gastrin Promoter Is Synergistically Activated by Transforming Growth Factor-{beta}/Smad and Wnt Signaling Pathways
J. Biol. Chem. 2004 279: 42492-42502. First Published on July 28, 2004; doi:10.1074/jbc.M404025200 [Abstract] [Full Text] [PDF]  

Chen Gao, Luming Wang, Elena Milgrom, and W.-C. Winston Shen
On the Mechanism of Constitutive Pdr1 Activator-mediated PDR5 Transcription in Saccharomyces cerevisiae: EVIDENCE FOR ENHANCED RECRUITMENT OF COACTIVATORS AND ALTERED NUCLEOSOME STRUCTURES
J. Biol. Chem. 2004 279: 42677-42686. First Published on August 4, 2004; doi:10.1074/jbc.M406363200 [Abstract] [Full Text] [PDF]  

Ineke P. Stolze, Ya-Min Tian, Rebecca J. Appelhoff, Helen Turley, Charles C. Wykoff, Jonathan M. Gleadle, and Peter J. Ratcliffe
Genetic Analysis of the Role of the Asparaginyl Hydroxylase Factor Inhibiting Hypoxia-inducible Factor (HIF) in Regulating HIF Transcriptional Target Genes
J. Biol. Chem. 2004 279: 42719-42725. First Published on August 9, 2004; doi:10.1074/jbc.M406713200 [Abstract] [Full Text] [PDF]  

Jung-Hee Lee, Mi-Hee Jeon, Yun-Jee Seo, Yong-Joon Lee, Jeong Heon Ko, Yoshihide Tsujimoto, and Jeong-Hwa Lee
CA Repeats in the 3'-Untranslated Region of bcl-2 mRNA Mediate Constitutive Decay of bcl-2 mRNA
J. Biol. Chem. 2004 279: 42758-42764. First Published on August 3, 2004; doi:10.1074/jbc.M407357200 [Abstract] [Full Text] [PDF] [Papers Of The Week]  

Hyun Soo Kim, Eun Shik Choi, Jin A Shin, Yeun Kyu Jang, and Sang Dai Park
Regulation of Swi6/HP1-dependent Heterochromatin Assembly by Cooperation of Components of the Mitogen-activated Protein Kinase Pathway and a Histone Deacetylase Clr6
J. Biol. Chem. 2004 279: 42850-42859. First Published on August 2, 2004; doi:10.1074/jbc.M407259200 [Abstract] [Full Text] [PDF]  


Protein Synthesis, Post-Translation Modification, and Degradation:

Olga Soutourina, Julie Soutourina, Sylvain Blanquet, and Pierre Plateau
Formation of D-Tyrosyl-tRNATyr Accounts for the Toxicity of D-Tyrosine toward Escherichia coli
J. Biol. Chem. 2004 279: 42560-42565. First Published on August 2, 2004; doi:10.1074/jbc.M402931200 [Abstract] [Full Text] [PDF]  

Charlotte L. Hanson, Hortense Videler, Cruz Santos, Juan P. G. Ballesta, and Carol V. Robinson
Mass Spectrometry of Ribosomes from Saccharomyces cerevisiae: IMPLICATIONS FOR ASSEMBLY OF THE STALK COMPLEX
J. Biol. Chem. 2004 279: 42750-42757. First Published on August 3, 2004; doi:10.1074/jbc.M405718200 [Abstract] [Full Text] [PDF]  

Elisabeth Traiffort, Christèle Dubourg, Hélène Faure, Didier Rognan, Sylvie Odent, Marie-Renée Durou, Véronique David, and Martial Ruat
Functional Characterization of Sonic Hedgehog Mutations Associated with Holoprosencephaly
J. Biol. Chem. 2004 279: 42889-42897. First Published on July 28, 2004; doi:10.1074/jbc.M405161200 [Abstract] [Full Text] [PDF]  

Yufang Zheng, Paul Saftig, Dieter Hartmann, and Carl Blobel
Evaluation of the Contribution of Different ADAMs to Tumor Necrosis Factor {alpha} (TNF{alpha}) Shedding and of the Function of the TNF{alpha} Ectodomain in Ensuring Selective Stimulated Shedding by the TNF{alpha} Convertase (TACE/ADAM17)
J. Biol. Chem. 2004 279: 42898-42906. First Published on August 2, 2004; doi:10.1074/jbc.M403193200 [Abstract] [Full Text] [PDF]  

Jianjun Sun and Joseph T. Barbieri
ExoS Rho GTPase-activating Protein Activity Stimulates Reorganization of the Actin Cytoskeleton through Rho GTPase Guanine Nucleotide Disassociation Inhibitor
J. Biol. Chem. 2004 279: 42936-42944. First Published on August 2, 2004; doi:10.1074/jbc.M406493200 [Abstract] [Full Text] [PDF]  

Nicole Poulsen and Nils Kröger
Silica Morphogenesis by Alternative Processing of Silaffins in the Diatom Thalassiosira pseudonana
J. Biol. Chem. 2004 279: 42993-42999. First Published on August 10, 2004; doi:10.1074/jbc.M407734200 [Abstract] [Full Text] [PDF]  

Qin Yan, Takumi Kamura, Yong Cai, Jingji Jin, Mircea Ivan, Arcady Mushegian, Ronald C. Conaway, and Joan Weliky Conaway
Identification of Elongin C and Skp1 Sequences That Determine Cullin Selection
J. Biol. Chem. 2004 279: 43019-43026. First Published on July 27, 2004; doi:10.1074/jbc.M408018200 [Abstract] [Full Text] [PDF]  

Jingshi Shen and Ron Prywes
Dependence of Site-2 Protease Cleavage of ATF6 on Prior Site-1 Protease Digestion Is Determined by the Size of the Luminal Domain of ATF6
J. Biol. Chem. 2004 279: 43046-43051. First Published on August 6, 2004; doi:10.1074/jbc.M408466200 [Abstract] [Full Text] [PDF]  

Nadeem Wajih, Terete Borras, Wei Xue, Susan M. Hutson, and Reidar Wallin
Processing and Transport of Matrix {gamma}-Carboxyglutamic Acid Protein and Bone Morphogenetic Protein-2 in Cultured Human Vascular Smooth Muscle Cells: EVIDENCE FOR AN UPTAKE MECHANISM FOR SERUM FETUIN
J. Biol. Chem. 2004 279: 43052-43060. First Published on July 27, 2004; doi:10.1074/jbc.M407180200 [Abstract] [Full Text] [PDF]  

Francisco M. Rausa, III, Douglas E. Hughes, and Robert H. Costa
Stability of the Hepatocyte Nuclear Factor 6 Transcription Factor Requires Acetylation by the CREB-binding Protein Coactivator
J. Biol. Chem. 2004 279: 43070-43076. First Published on August 9, 2004; doi:10.1074/jbc.M407472200 [Abstract] [Full Text] [PDF]  

Patricia M.-J. Lievens, Chiara Mutinelli, Darcie Baynes, and Elio Liboi
The Kinase Activity of Fibroblast Growth Factor Receptor 3 with Activation Loop Mutations Affects Receptor Trafficking and Signaling
J. Biol. Chem. 2004 279: 43254-43260. First Published on August 2, 2004; doi:10.1074/jbc.M405247200 [Abstract] [Full Text] [PDF]  

Deyarina Gonzalez, Jean-Claude Drapier, and Cécile Bouton
Endogenous Nitration of Iron Regulatory Protein-1 (IRP-1) in Nitric Oxide-producing Murine Macrophages: FURTHER INSIGHT INTO THE MECHANISM OF NITRATION IN VIVO AND ITS IMPACT ON IRP-1 FUNCTIONS
J. Biol. Chem. 2004 279: 43345-43351. First Published on July 16, 2004; doi:10.1074/jbc.M401889200 [Abstract] [Full Text] [PDF]  


Protein Structure and Folding:

Giuseppe D. Ciccotosto, Deborah Tew, Cyril C. Curtain, Danielle Smith, Darryl Carrington, Colin L. Masters, Ashley I. Bush, Robert A. Cherny, Roberto Cappai, and Kevin J. Barnham
Enhanced Toxicity and Cellular Binding of a Modified Amyloid {beta} Peptide with a Methionine to Valine Substitution
J. Biol. Chem. 2004 279: 42528-42534. First Published on July 28, 2004; doi:10.1074/jbc.M406465200 [Abstract] [Full Text] [PDF]  

Ashis Biswas and Kali P. Das
Role of ATP on the Interaction of {alpha}-Crystallin with Its Substrates and Its Implications for the Molecular Chaperone Function
J. Biol. Chem. 2004 279: 42648-42657. First Published on July 30, 2004; doi:10.1074/jbc.M404444200 [Abstract] [Full Text] [PDF]  

Dahabada H. J. Lopes, Christian Colin, Theri L. Degaki, Ana Christina V. de Sousa, Marcelo N. N. Vieira, Adriano Sebollela, Ana M. Blanco Martinez, Carlos Bloch, Jr., Sérgio T. Ferreira, and Mari C. Sogayar
Amyloidogenicity and Cytotoxicity of Recombinant Mature Human Islet Amyloid Polypeptide (rhIAPP)
J. Biol. Chem. 2004 279: 42803-42810. First Published on July 28, 2004; doi:10.1074/jbc.M406108200 [Abstract] [Full Text] [PDF]  

Lei Jin, Scott Pluskey, Eugene C. Petrella, Susan M. Cantin, Joan C. Gorga, Michael J. Rynkiewicz, Pramod Pandey, James E. Strickler, Robert E. Babine, David T. Weaver, and Katherine J. Seidl
The Three-dimensional Structure of the ZAP-70 Kinase Domain in Complex with Staurosporine: IMPLICATIONS FOR THE DESIGN OF SELECTIVE INHIBITORS
J. Biol. Chem. 2004 279: 42818-42825. First Published on July 29, 2004; doi:10.1074/jbc.M407096200 [Abstract] [Full Text] [PDF]  

Takehiko Tosha, Shiro Yoshioka, Koichiro Ishimori, and Isao Morishima
L358P Mutation on Cytochrome P450cam Simulates Structural Changes upon Putidaredoxin Binding: THE STRUCTURAL CHANGES TRIGGER ELECTRON TRANSFER TO OXY-P450CAM FROM ELECTRON DONORS
J. Biol. Chem. 2004 279: 42836-42843. First Published on July 21, 2004; doi:10.1074/jbc.M404216200 [Abstract] [Full Text] [PDF]  

David Nakar, Tal Handelsman, Yuval Shoham, Henri-Pierre Fierobe, Jean-Pierre Belaich, Ely Morag, Raphael Lamed, and Edward A. Bayer
Pinpoint Mapping of Recognition Residues on the Cohesin Surface by Progressive Homologue Swapping
J. Biol. Chem. 2004 279: 42881-42888. First Published on August 3, 2004; doi:10.1074/jbc.M407350200 [Abstract] [Full Text] [PDF] Supplemental Data  

Sara Lejon, Inga-Maria Frick, Lars Björck, Mats Wikström, and Stefan Svensson
Crystal Structure and Biological Implications of a Bacterial Albumin Binding Module in Complex with Human Serum Albumin
J. Biol. Chem. 2004 279: 42924-42928. First Published on July 21, 2004; doi:10.1074/jbc.M406957200 [Abstract] [Full Text] [PDF]  

Kenneth C. Ingham, Shelesa Brew, Dareyl Vaz, Daniel N. Sauder, and Martin J. McGavin
Interaction of Staphylococcus aureus Fibronectin-binding Protein with Fibronectin: AFFINITY, STOICHIOMETRY, AND MODULAR REQUIREMENTS
J. Biol. Chem. 2004 279: 42945-42953. First Published on August 4, 2004; doi:10.1074/jbc.M406984200 [Abstract] [Full Text] [PDF]  

Solomon A. Graf, Sarah E. Haigh, Erica D. Corson, and Orian S. Shirihai
Targeting, Import, and Dimerization of a Mammalian Mitochondrial ATP Binding Cassette (ABC) Transporter, ABCB10 (ABC-me)
J. Biol. Chem. 2004 279: 42954-42963. First Published on June 23, 2004; doi:10.1074/jbc.M405040200 [Abstract] [Full Text] [PDF]  

Wilhelm A. Weihofen, Jiango Liu, Werner Reutter, Wolfram Saenger, and Hua Fan
Crystal Structure of CD26/Dipeptidyl-peptidase IV in Complex with Adenosine Deaminase Reveals a Highly Amphiphilic Interface
J. Biol. Chem. 2004 279: 43330-43335. First Published on June 22, 2004; doi:10.1074/jbc.M405001200 [Abstract] [Full Text] [PDF] Supplemental Data  


Enzyme Catalysis and Regulation:

Hyun Soo Kim, Ursula Hoja, Juergen Stolz, Guido Sauer, and Eckhart Schweizer
Identification of the tRNA-binding Protein Arc1p as a Novel Target of in Vivo Biotinylation in Saccharomyces cerevisiae
J. Biol. Chem. 2004 279: 42445-42452. First Published on July 22, 2004; doi:10.1074/jbc.M407137200 [Abstract] [Full Text] [PDF]  

Fabrice Neiers, Alexandre Kriznik, Sandrine Boschi-Muller, and Guy Branlant
Evidence for a New Sub-class of Methionine Sulfoxide Reductases B with an Alternative Thioredoxin Recognition Signature
J. Biol. Chem. 2004 279: 42462-42468. First Published on July 26, 2004; doi:10.1074/jbc.M407464200 [Abstract] [Full Text] [PDF]  

Jinling Wang, Fernando Niemevz, Latesh Lad, Liusheng Huang, Diego E. Alvarez, Graciela Buldain, Thomas L. Poulos, and Paul R. Ortiz de Montellano
Human Heme Oxygenase Oxidation of 5- and 15-Phenylhemes
J. Biol. Chem. 2004 279: 42593-42604. First Published on August 5, 2004; doi:10.1074/jbc.M406346200 [Abstract] [Full Text] [PDF]  

Joseph M. Jez and Rebecca E. Cahoon
Kinetic Mechanism of Glutathione Synthetase from Arabidopsis thaliana
J. Biol. Chem. 2004 279: 42726-42731. First Published on August 9, 2004; doi:10.1074/jbc.M407961200 [Abstract] [Full Text] [PDF]  

Young-Wan Kim, Seung Seo Lee, R. Antony J. Warren, and Stephen G. Withers
Directed Evolution of a Glycosynthase from Agrobacterium sp. Increases Its Catalytic Activity Dramatically and Expands Its Substrate Repertoire
J. Biol. Chem. 2004 279: 42787-42793. First Published on July 13, 2004; doi:10.1074/jbc.M406890200 [Abstract] [Full Text] [PDF]  

Shingo Nagano, Takehiko Tosha, Koichiro Ishimori, Isao Morishima, and Thomas L. Poulos
Crystal Structure of the Cytochrome P450cam Mutant That Exhibits the Same Spectral Perturbations Induced by Putidaredoxin Binding
J. Biol. Chem. 2004 279: 42844-42849. First Published on July 21, 2004; doi:10.1074/jbc.M404217200 [Abstract] [Full Text] [PDF]  

Zhen Zhang and Timothy Palzkill
Dissecting the Protein-Protein Interface between {beta}-Lactamase Inhibitory Protein and Class A {beta}-Lactamases
J. Biol. Chem. 2004 279: 42860-42866. First Published on July 28, 2004; doi:10.1074/jbc.M406157200 [Abstract] [Full Text] [PDF]  

Orsolya Barabás, Veronika Pongrácz, Júlia Kovári, Matthias Wilmanns, and Beáta G. Vértessy
Structural Insights into the Catalytic Mechanism of Phosphate Ester Hydrolysis by dUTPase
J. Biol. Chem. 2004 279: 42907-42915. First Published on June 17, 2004; doi:10.1074/jbc.M406135200 [Abstract] [Full Text] [PDF] [Papers Of The Week]  

Christine A. Harman, Caroline Jill Rieke, R. Michael Garavito, and William L. Smith
Crystal Structure of Arachidonic Acid Bound to a Mutant of Prostaglandin Endoperoxide H Synthase-1 That Forms Predominantly 11-Hydroperoxyeicosatetraenoic Acid
J. Biol. Chem. 2004 279: 42929-42935. First Published on July 30, 2004; doi:10.1074/jbc.M403013200 [Abstract] [Full Text] [PDF]  

Tee Bordelon, Sarah K. Montegudo, Svetlana Pakhomova, Michael L. Oldham, and Marcia E. Newcomer
A Disorder to Order Transition Accompanies Catalysis in Retinaldehyde Dehydrogenase Type II
J. Biol. Chem. 2004 279: 43085-43091. First Published on August 7, 2004; doi:10.1074/jbc.M406139200 [Abstract] [Full Text] [PDF]  

Rahul Singh, Ben Wiseman, Taweewat Deemagarn, Lynda J. Donald, Harry W. Duckworth, Xavi Carpena, Ignacio Fita, and Peter C. Loewen
Catalase-peroxidases (KatG) Exhibit NADH Oxidase Activity
J. Biol. Chem. 2004 279: 43098-43106. First Published on July 26, 2004; doi:10.1074/jbc.M406374200 [Abstract] [Full Text] [PDF]  

Andrew C. Nyborg, Karen Jansen, Thomas B. Ladd, Abdul Fauq, and Todd E. Golde
A Signal Peptide Peptidase (SPP) Reporter Activity Assay Based on the Cleavage of Type II Membrane Protein Substrates Provides Further Evidence for an Inverted Orientation of the SPP Active Site Relative to Presenilin
J. Biol. Chem. 2004 279: 43148-43156. First Published on July 12, 2004; doi:10.1074/jbc.M405879200 [Abstract] [Full Text] [PDF]  

Jason T. Maynes, Kathleen R. Perreault, Maia M. Cherney, Hue Anh Luu, Michael N. G. James, and Charles F. B. Holmes
Crystal Structure and Mutagenesis of a Protein Phosphatase-1:Calcineurin Hybrid Elucidate the Role of the {beta}12-{beta}13 Loop in Inhibitor Binding
J. Biol. Chem. 2004 279: 43198-43206. First Published on July 26, 2004; doi:10.1074/jbc.M407184200 [Abstract] [Full Text] [PDF]  

Yolanda M. Fortenberry, Herbert C. Whinna, Holly R. Gentry, Timothy Myles, Lawrence L. K. Leung, and Frank C. Church
Molecular Mapping of the Thrombin-Heparin Cofactor II Complex
J. Biol. Chem. 2004 279: 43237-43244. First Published on August 2, 2004; doi:10.1074/jbc.M406716200 [Abstract] [Full Text] [PDF]  

Ken Sawada, Zhe Yang, John R. Horton, Robert E. Collins, Xing Zhang, and Xiaodong Cheng
Structure of the Conserved Core of the Yeast Dot1p, a Nucleosomal Histone H3 Lysine 79 Methyltransferase
J. Biol. Chem. 2004 279: 43296-43306. First Published on July 29, 2004; doi:10.1074/jbc.M405902200 [Abstract] [Full Text] [PDF]  

Eric M. Tam, Todd R. Moore, Georgina S. Butler, and Christopher M. Overall
Characterization of the Distinct Collagen Binding, Helicase and Cleavage Mechanisms of Matrix Metalloproteinase 2 and 14 (Gelatinase A and MT1-MMP): THE DIFFERENTIAL ROLES OF THE MMP HEMOPEXIN C DOMAINS AND THE MMP-2 FIBRONECTIN TYPE II MODULES IN COLLAGEN TRIPLE HELICASE ACTIVITIES
J. Biol. Chem. 2004 279: 43336-43344. First Published on August 2, 2004; doi:10.1074/jbc.M407186200 [Abstract] [Full Text] [PDF]  


Metabolism and Bioenergetics:

Vishal M. Gohil, Paulette Hayes, Shigemi Matsuyama, Hermann Schägger, Michael Schlame, and Miriam L. Greenberg
Cardiolipin Biosynthesis and Mitochondrial Respiratory Chain Function Are Interdependent
J. Biol. Chem. 2004 279: 42612-42618. First Published on July 29, 2004; doi:10.1074/jbc.M402545200 [Abstract] [Full Text] [PDF]  

Terttu Suormala, Matthias R. Baumgartner, David Coelho, Petra Zavadakova, Viktor Kozich, Hans Georg Koch, Martin Berghaüser, James E. Wraith, Alberto Burlina, Adrian Sewell, Jürgen Herwig, and Brian Fowler
The cblD Defect Causes Either Isolated or Combined Deficiency of Methylcobalamin and Adenosylcobalamin Synthesis
J. Biol. Chem. 2004 279: 42742-42749. First Published on August 2, 2004; doi:10.1074/jbc.M407733200 [Abstract] [Full Text] [PDF]  

Johanna E. Cornah, Véronique Germain, Jane L. Ward, Michael H. Beale, and Steven M. Smith
Lipid Utilization, Gluconeogenesis, and Seedling Growth in Arabidopsis Mutants Lacking the Glyoxylate Cycle Enzyme Malate Synthase
J. Biol. Chem. 2004 279: 42916-42923. First Published on July 22, 2004; doi:10.1074/jbc.M407380200 [Abstract] [Full Text] [PDF]  

Michael Klemba, Ilya Gluzman, and Daniel E. Goldberg
A Plasmodium falciparum Dipeptidyl Aminopeptidase I Participates in Vacuolar Hemoglobin Degradation
J. Biol. Chem. 2004 279: 43000-43007. First Published on August 10, 2004; doi:10.1074/jbc.M408123200 [Abstract] [Full Text] [PDF]  

Xin Zhang, Annette Shoba Vincent, Barry Halliwell, and Kim Ping Wong
A Mechanism of Sulfite Neurotoxicity: DIRECT INHIBITION OF GLUTAMATE DEHYDROGENASE
J. Biol. Chem. 2004 279: 43035-43045. First Published on July 23, 2004; doi:10.1074/jbc.M402759200 [Abstract] [Full Text] [PDF]  

Ilya R. Bederman, Aneta E. Reszko, Takhar Kasumov, France David, David H. Wasserman, Joanne K. Kelleher, and Henri Brunengraber
Zonation of Labeling of Lipogenic Acetyl-CoA across the Liver: IMPLICATIONS FOR STUDIES OF LIPOGENESIS BY MASS ISOTOPOMER ANALYSIS
J. Biol. Chem. 2004 279: 43207-43216. First Published on July 28, 2004; doi:10.1074/jbc.M403838200 [Abstract] [Full Text] [PDF]  

Ilya R. Bederman, Takhar Kasumov, Aneta E. Reszko, France David, Henri Brunengraber, and Joanne K. Kelleher
In Vitro Modeling of Fatty Acid Synthesis under Conditions Simulating the Zonation of Lipogenic [13C]Acetyl-CoA Enrichment in the Liver
J. Biol. Chem. 2004 279: 43217-43226. First Published on July 28, 2004; doi:10.1074/jbc.M403837200 [Abstract] [Full Text] [PDF] Supplemental Data  


Glycobiology and Extracellular Matrices:

Christian Götting, Sandra Müller, Manuela Schöttler, Sylvia Schön, Christian Prante, Thomas Brinkmann, Joachim Kuhn, and Knut Kleesiek
Analysis of the DXD Motifs in Human Xylosyltransferase I Required for Enzyme Activity
J. Biol. Chem. 2004 279: 42566-42573. First Published on August 4, 2004; doi:10.1074/jbc.M401340200 [Abstract] [Full Text] [PDF]  

Tomomi Ichimiya, Hiroshi Manya, Yoshiko Ohmae, Hideki Yoshida, Kuniaki Takahashi, Ryu Ueda, Tamao Endo, and Shoko Nishihara
The Twisted Abdomen Phenotype of Drosophila POMT1 and POMT2 Mutants Coincides with Their Heterophilic Protein O-Mannosyltransferase Activity
J. Biol. Chem. 2004 279: 42638-42647. First Published on July 22, 2004; doi:10.1074/jbc.M404900200 [Abstract] [Full Text] [PDF]  

Johan Ledin, William Staatz, Jin-Ping Li, Martin Götte, Scott Selleck, Lena Kjellén, and Dorothe Spillmann
Heparan Sulfate Structure in Mice with Genetically Modified Heparan Sulfate Production
J. Biol. Chem. 2004 279: 42732-42741. First Published on July 29, 2004; doi:10.1074/jbc.M405382200 [Abstract] [Full Text] [PDF]  

Seshu K. Gudlavalleti, Anup K. Datta, Yih-Ling Tzeng, Corie Noble, Russell W. Carlson, and David S. Stephens
The Neisseria meningitidis Serogroup A Capsular Polysaccharide O-3 and O-4 Acetyltransferase
J. Biol. Chem. 2004 279: 42765-42773. First Published on August 4, 2004; doi:10.1074/jbc.M313552200 [Abstract] [Full Text] [PDF]  

Hidefumi Kitazawa, Tamao Nishihara, Tadahiro Nambu, Hitoshi Nishizawa, Masanori Iwaki, Atsunori Fukuhara, Toshio Kitamura, Morihiro Matsuda, and Iichiro Shimomura
Intectin, a Novel Small Intestine-specific Glycosylphosphatidylinositol-anchored Protein, Accelerates Apoptosis of Intestinal Epithelial Cells
J. Biol. Chem. 2004 279: 42867-42874. First Published on July 28, 2004; doi:10.1074/jbc.M408047200 [Abstract] [Full Text] [PDF]  


Lipids and Lipoproteins:

Robert J. Brown, André Gauthier, Robin J. Parks, Ruth McPherson, Daniel L. Sparks, Joshua R. Schultz, and Zemin Yao
Severe Hypoalphalipoproteinemia in Mice Expressing Human Hepatic Lipase Deficient in Binding to Heparan Sulfate Proteoglycan
J. Biol. Chem. 2004 279: 42403-42409. First Published on August 2, 2004; doi:10.1074/jbc.M407748200 [Abstract] [Full Text] [PDF]  

Esther Pérez, Patricia Constant, Anne Lemassu, Françoise Laval, Mamadou Daffé, and Christophe Guilhot
Characterization of Three Glycosyltransferases Involved in the Biosynthesis of the Phenolic Glycolipid Antigens from the Mycobacterium tuberculosis Complex
J. Biol. Chem. 2004 279: 42574-42583. First Published on August 3, 2004; doi:10.1074/jbc.M406246200 [Abstract] [Full Text] [PDF]  

Esther Pérez, Patricia Constant, Françoise Laval, Anne Lemassu, Marie-Antoinette Lanéelle, Mamadou Daffé, and Christophe Guilhot
Molecular Dissection of the Role of Two Methyltransferases in the Biosynthesis of Phenolglycolipids and Phthiocerol Dimycoserosate in the Mycobacterium tuberculosis Complex
J. Biol. Chem. 2004 279: 42584-42592. First Published on August 3, 2004; doi:10.1074/jbc.M406134200 [Abstract] [Full Text] [PDF]  

Akira Abe, Miki Hiraoka, Susan Wild, Steven E. Wilcoxen, Robert Paine, III, and James A. Shayman
Lysosomal Phospholipase A2 Is Selectively Expressed in Alveolar Macrophages
J. Biol. Chem. 2004 279: 42605-42611. First Published on August 4, 2004; doi:10.1074/jbc.M407834200 [Abstract] [Full Text] [PDF]  

Virginie Vallet-Erdtmann, Geneviève Tavernier, Juan Antonio Contreras, Aline Mairal, Cécile Rieu, Anne-Marie Touzalin, Cecilia Holm, Bernard Jégou, and Dominique Langin
The Testicular Form of Hormone-sensitive Lipase HSLtes Confers Rescue of Male Infertility in HSL-deficient Mice
J. Biol. Chem. 2004 279: 42875-42880. First Published on July 28, 2004; doi:10.1074/jbc.M403495200 [Abstract] [Full Text] [PDF]  

Subramaniam Pennathur, Constanze Bergt, Baohai Shao, Jaeman Byun, Sean Y. Kassim, Pragya Singh, Pattie S. Green, Thomas O. McDonald, John Brunzell, Alan Chait, John F. Oram, Kevin O'Brien, Randolph L. Geary, and Jay W. Heinecke
Human Atherosclerotic Intima and Blood of Patients with Established Coronary Artery Disease Contain High Density Lipoprotein Damaged by Reactive Nitrogen Species
J. Biol. Chem. 2004 279: 42977-42983. First Published on August 2, 2004; doi:10.1074/jbc.M406762200 [Abstract] [Full Text] [PDF]  

Navdar Sever, Peter C. W. Lee, Bao-Liang Song, Robert B. Rawson, and Russell A. DeBose-Boyd
Isolation of Mutant Cells Lacking Insig-1 through Selection with SR-12813, an Agent That Stimulates Degradation of 3-Hydroxy-3-methylglutaryl-Coenzyme A Reductase
J. Biol. Chem. 2004 279: 43136-43147. First Published on July 7, 2004; doi:10.1074/jbc.M406406200 [Abstract] [Full Text] [PDF]  


Membrane Transport, Structure, Function, and Biogenesis:

Anne Crausaz Esseiva, Arunasalam Naguleswaran, Andrew Hemphill, and André Schneider
Mitochondrial tRNA Import in Toxoplasma gondii
J. Biol. Chem. 2004 279: 42363-42368. First Published on July 27, 2004; doi:10.1074/jbc.M404519200 [Abstract] [Full Text] [PDF]  

Timothy A. Reinhardt, John D. Lippolis, Gary E. Shull, and Ronald L. Horst
Null Mutation in the Gene Encoding Plasma Membrane Ca2+-ATPase Isoform 2 Impairs Calcium Transport into Milk
J. Biol. Chem. 2004 279: 42369-42373. First Published on August 9, 2004; doi:10.1074/jbc.M407788200 [Abstract] [Full Text] [PDF]  

Carmen Spatuzza, Maurizio Renna, Raffaella Faraonio, Giorgia Cardinali, Gianluca Martire, Stefano Bonatti, and Paolo Remondelli
Heat Shock Induces Preferential Translation of ERGIC-53 and Affects Its Recycling Pathway
J. Biol. Chem. 2004 279: 42535-42544. First Published on July 29, 2004; doi:10.1074/jbc.M401860200 [Abstract] [Full Text] [PDF] Supplemental Data  

Nestor L. Uzcategui, Alexander Szallies, Slavica Pavlovic-Djuranovic, Monica Palmada, Katherine Figarella, Christoph Boehmer, Florian Lang, Eric Beitz, and Michael Duszenko
Cloning, Heterologous Expression, and Characterization of Three Aquaglyceroporins from Trypanosoma brucei
J. Biol. Chem. 2004 279: 42669-42676. First Published on August 4, 2004; doi:10.1074/jbc.M404518200 [Abstract] [Full Text] [PDF]  

Richard Lundmark and Sven R. Carlsson
Regulated Membrane Recruitment of Dynamin-2 Mediated by Sorting Nexin 9
J. Biol. Chem. 2004 279: 42694-42702. First Published on August 6, 2004; doi:10.1074/jbc.M407430200 [Abstract] [Full Text] [PDF]  

Xinpu Chen and John L. Spudich
Five Residues in the HtrI Transducer Membrane-proximal Domain Close the Cytoplasmic Proton-conducting Channel of Sensory Rhodopsin I
J. Biol. Chem. 2004 279: 42964-42969. First Published on July 13, 2004; doi:10.1074/jbc.M406503200 [Abstract] [Full Text] [PDF]  

Chii-Shen Yang, Oleg Sineshchekov, Elena N. Spudich, and John L. Spudich
The Cytoplasmic Membrane-proximal Domain of the HtrII Transducer Interacts with the E-F Loop of Photoactivated Natronomonas pharaonis Sensory Rhodopsin II
J. Biol. Chem. 2004 279: 42970-42976. First Published on July 15, 2004; doi:10.1074/jbc.M406504200 [Abstract] [Full Text] [PDF]  

Robyn L. Goforth, Eric C. Peterson, Jianguo Yuan, Misty J. Moore, Alicia D. Kight, Matthew B. Lohse, Joshua Sakon, and Ralph L. Henry
Regulation of the GTPase Cycle in Post-translational Signal Recognition Particle-based Protein Targeting Involves cpSRP43
J. Biol. Chem. 2004 279: 43077-43084. First Published on August 2, 2004; doi:10.1074/jbc.M401600200 [Abstract] [Full Text] [PDF]  

Ziying Han and Ronald N. Harty
The NS3 Protein of Bluetongue Virus Exhibits Viroporin-like Properties
J. Biol. Chem. 2004 279: 43092-43097. First Published on August 3, 2004; doi:10.1074/jbc.M403663200 [Abstract] [Full Text] [PDF]  

Joshua L. Hood, William H. Brooks, and Thomas L. Roszman
Differential Compartmentalization of the Calpain/Calpastatin Network with the Endoplasmic Reticulum and Golgi Apparatus
J. Biol. Chem. 2004 279: 43126-43135. First Published on August 9, 2004; doi:10.1074/jbc.M408100200 [Abstract] [Full Text] [PDF]  

Hong C. Li, Roger T. Worrell, Jeffrey B. Matthews, Holleh Husseinzadeh, Lisa Neumeier, Snezana Petrovic, Laura Conforti, and Manoocher Soleimani
Identification of a Carboxyl-terminal Motif Essential for the Targeting of Na+-HCO-3 Cotransporter NBC1 to the Basolateral Membrane
J. Biol. Chem. 2004 279: 43190-43197. First Published on July 25, 2004; doi:10.1074/jbc.M405780200 [Abstract] [Full Text] [PDF]  

Zerihun Assefa, Geert Bultynck, Karolina Szlufcik, Nael Nadif Kasri, Elke Vermassen, Jozef Goris, Ludwig Missiaen, Geert Callewaert, Jan B. Parys, and Humbert De Smedt
Caspase-3-induced Truncation of Type 1 Inositol Trisphosphate Receptor Accelerates Apoptotic Cell Death and Induces Inositol Trisphosphate-independent Calcium Release during Apoptosis
J. Biol. Chem. 2004 279: 43227-43236. First Published on July 28, 2004; doi:10.1074/jbc.M403872200 [Abstract] [Full Text] [PDF]  

Raphaël Rozenfeld, Laurent Muller, Said El Messari, and Catherine Llorens-Cortes
The C-terminal Domain of Aminopeptidase A Is an Intramolecular Chaperone Required for the Correct Folding, Cell Surface Expression, and Activity of This Monozinc Aminopeptidase
J. Biol. Chem. 2004 279: 43285-43295. First Published on July 19, 2004; doi:10.1074/jbc.M404369200 [Abstract] [Full Text] [PDF]  


Mechanisms Of Signal Transduction:

Thomas R. Ott, Anil Pahuja, Sarah A. Nickolls, David G. Alleva, and R. Scott Struthers
Identification of CC Chemokine Receptor 7 Residues Important for Receptor Activation
J. Biol. Chem. 2004 279: 42383-42392. First Published on July 28, 2004; doi:10.1074/jbc.M401097200 [Abstract] [Full Text] [PDF]  

Julia E. Brittain, Jaewon Han, Kenneth I. Ataga, Eugene P. Orringer, and Leslie V. Parise
Mechanism of CD47-induced {alpha}4{beta}1 Integrin Activation and Adhesion in Sickle Reticulocytes
J. Biol. Chem. 2004 279: 42393-42402. First Published on July 29, 2004; doi:10.1074/jbc.M407631200 [Abstract] [Full Text] [PDF]  

Zhenyu Li, Guoying Zhang, Jasna Ajdic Marjanovic, Changgeng Ruan, and Xiaoping Du
A Platelet Secretion Pathway Mediated by cGMP-dependent Protein Kinase
J. Biol. Chem. 2004 279: 42469-42475. First Published on July 27, 2004; doi:10.1074/jbc.M401532200 [Abstract] [Full Text] [PDF]  

Emmanuel Culetto, Howard A. Baylis, Janet E. Richmond, Andrew K. Jones, John T. Fleming, Michael D. Squire, James A. Lewis, and David B. Sattelle
The Caenorhabditis elegans unc-63 Gene Encodes a Levamisole-sensitive Nicotinic Acetylcholine Receptor {alpha} Subunit
J. Biol. Chem. 2004 279: 42476-42483. First Published on July 27, 2004; doi:10.1074/jbc.M404370200 [Abstract] [Full Text] [PDF]  

Naoka Murakami, Takehiko Yokomizo, Toshiaki Okuno, and Takao Shimizu
G2A Is a Proton-sensing G-protein-coupled Receptor Antagonized by Lysophosphatidylcholine
J. Biol. Chem. 2004 279: 42484-42491. First Published on July 27, 2004; doi:10.1074/jbc.M406561200 [Abstract] [Full Text] [PDF]  

Yutaka Masuda, Genryu Shima, Toshihiro Aiuchi, Masayo Horie, Kouichi Hori, Shigeo Nakajo, Sachiko Kajimoto, Toshiko Shibayama-Imazu, and Kazuyasu Nakaya
Involvement of Tumor Necrosis Factor Receptor-associated Protein 1 (TRAP1) in Apoptosis Induced by {beta}-Hydroxyisovalerylshikonin
J. Biol. Chem. 2004 279: 42503-42515. First Published on July 28, 2004; doi:10.1074/jbc.M404256200 [Abstract] [Full Text] [PDF]  

Federica Chiara, Marie-José Goumans, Henrik Forsberg, Aive Ahgrén, Andrea Rasola, Pontus Aspenström, Christer Wernstedt, Carina Hellberg, Carl-Henrik Heldin, and Rainer Heuchel
A Gain of Function Mutation in the Activation Loop of Plateletderived Growth Factor {beta}-Receptor Deregulates Its Kinase Activity
J. Biol. Chem. 2004 279: 42516-42527. First Published on July 28, 2004; doi:10.1074/jbc.M406051200 [Abstract] [Full Text] [PDF] Supplemental Data  

Tianbao Yang, Shubho Chaudhuri, Lihua Yang, Yanping Chen, and B. W. Poovaiah
Calcium/Calmodulin Up-regulates a Cytoplasmic Receptor-like Kinase in Plants
J. Biol. Chem. 2004 279: 42552-42559. First Published on August 2, 2004; doi:10.1074/jbc.M402830200 [Abstract] [Full Text] [PDF]  

Iván Muñoz, Amparo Ruiz, Maribel Marquina, Anna Barceló, Armando Albert, and Joaquín Ariño
Functional Characterization of the Yeast Ppz1 Phosphatase Inhibitory Subunit Hal3: A MUTAGENESIS STUDY
J. Biol. Chem. 2004 279: 42619-42627. First Published on July 29, 2004; doi:10.1074/jbc.M405656200 [Abstract] [Full Text] [PDF] Supplemental Data  

Isabelle Mothe-Satney, Nadine Gautier, Charlotte Hinault, John C. Lawrence, Jr., and Emmanuel Van Obberghen
In Rat Hepatocytes Glucagon Increases Mammalian Target of Rapamycin Phosphorylation on Serine 2448 but Antagonizes the Phosphorylation of Its Downstream Targets Induced by Insulin and Amino Acids
J. Biol. Chem. 2004 279: 42628-42637. First Published on August 2, 2004; doi:10.1074/jbc.M405173200 [Abstract] [Full Text] [PDF]  

Michael A. Bachelor and G. Timothy Bowden
Ultraviolet A-induced Modulation of Bcl-XL by p38 MAPK in Human Keratinocytes: POST-TRANSCRIPTIONAL REGULATION THROUGH THE 3'-UNTRANSLATED REGION
J. Biol. Chem. 2004 279: 42658-42668. First Published on August 2, 2004; doi:10.1074/jbc.M406626200 [Abstract] [Full Text] [PDF]  

Richard L. Bennett, William L. Blalock, and W. Stratford May
Serine 18 Phosphorylation of RAX, the PKR Activator, Is Required for PKR Activation and Consequent Translation Inhibition
J. Biol. Chem. 2004 279: 42687-42693. First Published on August 6, 2004; doi:10.1074/jbc.M403321200 [Abstract] [Full Text] [PDF]  

Endre Kiss-Toth, Stephanie M. Bagstaff, Hye Y. Sung, Veronika Jozsa, Clare Dempsey, Jim C. Caunt, Kevin M. Oxley, David H. Wyllie, Timea Polgar, Mary Harte, Luke A. J. O'Neill, Eva E. Qwarnstrom, and Steven K. Dower
Human Tribbles, a Protein Family Controlling Mitogen-activated Protein Kinase Cascades
J. Biol. Chem. 2004 279: 42703-42708. First Published on August 6, 2004; doi:10.1074/jbc.M407732200 [Abstract] [Full Text] [PDF] Supplemental Data  

Meng Qiao, Paul Shapiro, Rakesh Kumar, and Antonino Passaniti
Insulin-like Growth Factor-1 Regulates Endogenous RUNX2 Activity in Endothelial Cells through a Phosphatidylinositol 3-Kinase/ERK-dependent and Akt-independent Signaling Pathway
J. Biol. Chem. 2004 279: 42709-42718. First Published on August 9, 2004; doi:10.1074/jbc.M404480200 [Abstract] [Full Text] [PDF]  

Hidemitsu Nakajima, Hiroshi Nagaso, Nobukazu Kakui, Midori Ishikawa, Toyokazu Hiranuma, and Shigeru Hoshiko
Critical Role of the Automodification of Poly(ADP-ribose) Polymerase-1 in Nuclear Factor-{kappa}B-dependent Gene Expression in Primary Cultured Mouse Glial Cells
J. Biol. Chem. 2004 279: 42774-42786. First Published on August 9, 2004; doi:10.1074/jbc.M407923200 [Abstract] [Full Text] [PDF]  

Jean-Christophe Bambou, Antoine Giraud, Sandrine Menard, Bernadette Begue, Sabine Rakotobe, Martine Heyman, François Taddei, Nadine Cerf-Bensussan, and Valérie Gaboriau-Routhiau
In Vitro and ex Vivo Activation of the TLR5 Signaling Pathway in Intestinal Epithelial Cells by a Commensal Escherichia coli Strain
J. Biol. Chem. 2004 279: 42984-42992. First Published on August 9, 2004; doi:10.1074/jbc.M405410200 [Abstract] [Full Text] [PDF]  

Yuzuru Ikehara, Sanae Kabata Ikehara, and James C. Paulson
Negative Regulation of T Cell Receptor Signaling by Siglec-7 (p70/AIRM) and Siglec-9
J. Biol. Chem. 2004 279: 43117-43125. First Published on August 3, 2004; doi:10.1074/jbc.M403538200 [Abstract] [Full Text] [PDF]  

Sandeep C. Pingle, Snigdha Mishra, Adriana Marcuzzi, Satyanarayan G. Bhat, Yuko Sekino, Leonard P. Rybak, and Vickram Ramkumar
Osmotic Diuretics Induce Adenosine A1 Receptor Expression and Protect Renal Proximal Tubular Epithelial Cells against Cisplatin-mediated Apoptosis
J. Biol. Chem. 2004 279: 43157-43167. First Published on July 22, 2004; doi:10.1074/jbc.M405666200 [Abstract] [Full Text] [PDF]  

Corinna Steindler, Zhi Li, Michèle Algarté, Andrès Alcover, Valentina Libri, Josiane Ragimbeau, and Sandra Pellegrini
Jamip1 (Marlin-1) Defines a Family of Proteins Interacting with Janus Kinases and Microtubules
J. Biol. Chem. 2004 279: 43168-43177. First Published on July 23, 2004; doi:10.1074/jbc.M401915200 [Abstract] [Full Text] [PDF]  

Renae K. Barr, Richard M. Hopkins, Paul M. Watt, and Marie A. Bogoyevitch
Reverse Two-hybrid Screening Identifies Residues of JNK Required for Interaction with the Kinase Interaction Motif of JNK-interacting Protein-1
J. Biol. Chem. 2004 279: 43178-43189. First Published on July 22, 2004; doi:10.1074/jbc.M405900200 [Abstract] [Full Text] [PDF]  

Amy E. Moran, Daniel H. Hunt, Sara H. Javid, Mark Redston, Adelaide M. Carothers, and Monica M. Bertagnolli
Apc Deficiency Is Associated with Increased Egfr Activity in the Intestinal Enterocytes and Adenomas of C57BL/6J-Min/+ Mice
J. Biol. Chem. 2004 279: 43261-43272. First Published on August 4, 2004; doi:10.1074/jbc.M404276200 [Abstract] [Full Text] [PDF]  

Cornelia Weiss-Haljiti, Christian Pasquali, Hong Ji, Corine Gillieron, Christian Chabert, Marie-Laure Curchod, Emilio Hirsch, Anne J. Ridley, Rob Hooft van Huijsduijnen, Montserrat Camps, and Christian Rommel
Involvement of Phosphoinositide 3-Kinase {gamma}, Rac, and PAK Signaling in Chemokine-induced Macrophage Migration
J. Biol. Chem. 2004 279: 43273-43284. First Published on July 29, 2004; doi:10.1074/jbc.M402924200 [Abstract] [Full Text] [PDF]  

Laurent Meertens, Sébastien Chevalier, Robert Weil, Antoine Gessain, and Renaud Mahieux
A 10-Amino Acid Domain within Human T-cell Leukemia Virus Type 1 and Type 2 Tax Protein Sequences Is Responsible for Their Divergent Subcellular Distribution
J. Biol. Chem. 2004 279: 43307-43320. First Published on July 21, 2004; doi:10.1074/jbc.M400497200 [Abstract] [Full Text] [PDF] Supplemental Data  

Anastasia Constantinescu, Meiye Wu, Orna Asher, and Ivan Diamond
cAMP-dependent Protein Kinase Type I Regulates Ethanol-induced cAMP Response Element-mediated Gene Expression via Activation of CREB-binding Protein and Inhibition of MAPK
J. Biol. Chem. 2004 279: 43321-43329. First Published on August 6, 2004; doi:10.1074/jbc.M406994200 [Abstract] [Full Text] [PDF]  

Pawan Kumar, April I. Miller, and Peter J. Polverini
p38 MAPK Mediates {gamma}-Irradiation-induced Endothelial Cell Apoptosis, and Vascular Endothelial Growth Factor Protects Endothelial Cells through the Phosphoinositide 3-Kinase-Akt-Bcl-2 Pathway
J. Biol. Chem. 2004 279: 43352-43360. First Published on August 2, 2004; doi:10.1074/jbc.M405777200 [Abstract] [Full Text] [PDF]  


Molecular Basis Of Cell and Developmental Biology:

Kathryn E. Davis, Marthe Moldes, and Stephen R. Farmer
The Forkhead Transcription Factor FoxC2 Inhibits White Adipocyte Differentiation
J. Biol. Chem. 2004 279: 42453-42461. First Published on July 23, 2004; doi:10.1074/jbc.M402197200 [Abstract] [Full Text] [PDF]  

Ye Zhang, Jin-Shan Wang, Li-Ling Chen, Yong Zhang, Xiao-Kuan Cheng, Feng-Yan Heng, Ning-Hua Wu, and Yu-Fei Shen
Repression of hsp90{beta} Gene by p53 in UV Irradiation-induced Apoptosis of Jurkat Cells
J. Biol. Chem. 2004 279: 42545-42551. First Published on July 28, 2004; doi:10.1074/jbc.M314213200 [Abstract] [Full Text] [PDF]  

Eric C. Schirmer and Larry Gerace
The Stability of the Nuclear Lamina Polymer Changes with the Composition of Lamin Subtypes According to Their Individual Binding Strengths
J. Biol. Chem. 2004 279: 42811-42817. First Published on July 27, 2004; doi:10.1074/jbc.M407705200 [Abstract] [Full Text] [PDF]  

Kiichiro Tomoda, Noriko Yoneda-Kato, Akihisa Fukumoto, Shinya Yamanaka, and Jun-ya Kato
Multiple Functions of Jab1 Are Required for Early Embryonic Development and Growth Potential in Mice
J. Biol. Chem. 2004 279: 43013-43018. First Published on August 6, 2004; doi:10.1074/jbc.M406559200 [Abstract] [Full Text] [PDF]  

Xiang-Ming Zhang, Sarah Ellis, Absorn Sriratana, Christina A. Mitchell, and Tony Rowe
Sec15 Is an Effector for the Rab11 GTPase in Mammalian Cells
J. Biol. Chem. 2004 279: 43027-43034. First Published on July 29, 2004; doi:10.1074/jbc.M402264200 [Abstract] [Full Text] [PDF]  

Stéphane Fouquet, Verónica-Haydée Lugo-Martínez, Anne-Marie Faussat, Flore Renaud, Philippe Cardot, Jean Chambaz, Martine Pinçon-Raymond, and Sophie Thenet
Early Loss of E-cadherin from Cell-Cell Contacts Is Involved in the Onset of Anoikis in Enterocytes
J. Biol. Chem. 2004 279: 43061-43069. First Published on August 2, 2004; doi:10.1074/jbc.M405095200 [Abstract] [Full Text] [PDF]  

Yunjun Liao, Olga N. Shikapwashya, Eyal Shteyer, Brian K. Dieckgraefe, Paul W. Hruz, and David A. Rudnick
Delayed Hepatocellular Mitotic Progression and Impaired Liver Regeneration in Early Growth Response-1-deficient Mice
J. Biol. Chem. 2004 279: 43107-43116. First Published on July 20, 2004; doi:10.1074/jbc.M407969200 [Abstract] [Full Text] [PDF]  

Tadahiro Numakawa, Tetsuya Ishimoto, Shingo Suzuki, Yumiko Numakawa, Naoki Adachi, Tomoya Matsumoto, Daisaku Yokomaku, Hisatsugu Koshimizu, Kazuhiro E. Fujimori, Ryota Hashimoto, Takahisa Taguchi, and Hiroshi Kunugi
Neuronal Roles of the Integrin-associated Protein (IAP/CD47) in Developing Cortical Neurons
J. Biol. Chem. 2004 279: 43245-43253. First Published on August 5, 2004; doi:10.1074/jbc.M406733200 [Abstract] [Full Text] [PDF] Supplemental Data  


Additions and Corrections:

Jan Jakubík, Esam E. El-Fakahany, and Stanislav Tucek
Evidence for a tandem two-site model of ligand binding to muscarinic acetylcholine receptors. Vol. 275 (2000) 18836-18844
J. Biol. Chem. 2004 279: 43361. [Full Text] [PDF]  

Yongmin Liu, Gregory L. Borchert, and James M. Phang
Polyoma enhancer activator 3, an Ets transcription factor, mediates the induction of cyclooxygenase-2 by nitric oxide in colorectal cancer cells. Vol. 279 (2004) 18694-18700
J. Biol. Chem. 2004 279: 43362. [Full Text] [PDF]  

Eric E. Kelley, Andrés Trostchansky, Homero Rubbo, Bruce A. Freeman, Rafael Radi, and Margaret M. Tarpey
Binding of xanthine oxidase to glycosaminoglycans limits inhibition by oxypurinol. Vol. 279 (2004) 37231-37234
J. Biol. Chem. 2004 279: 43362-a. [Full Text] [PDF]  


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