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Table of Contents: May 6 2005; 280 (18)   [Index by Author]  [Papers Of The Week]
[Cover Figure and Caption]
      Down Papers Of The Week
      Down Classics
      Down DNA: Replication, Repair, and Recombination
      Down Genes: Structure and Regulation
      Down RNA: Structure, Metabolism, and Catalysis
      Down Protein Synthesis, Post-Translation Modification, and Degradation
      Down Genomics, Proteomics, and Bioinformatics
      Down Protein Structure and Folding
      Down Enzyme Catalysis and Regulation
      Down Metabolism and Bioenergetics
      Down Glycobiology and Extracellular Matrices
      Down Lipids and Lipoproteins
      Down Membrane Transport, Structure, Function, and Biogenesis
      Down Mechanisms Of Signal Transduction
      Down Molecular Basis Of Cell and Developmental Biology
      Down Additions and Corrections
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Papers Of The Week:Back

The in Vivo Dynamics of Nuclear Receptors
J. Biol. Chem. 2005 280: e99920. [Full Text] [PDF]  

A Look at Nucleosidase Transition State Analogue Binding
J. Biol. Chem. 2005 280: e99921. [Full Text] [PDF]  


Classics:Back

Nicole Kresge, Robert D. Simoni, and Robert L. Hill
The Discovery of Heterotrophic Carbon Dioxide Fixation by Harland G. Wood
HEAVY CARBON AS A TRACER IN HETEROTROPHIC CARBON DIOXIDE ASSIMILATION (H. G. Wood, C. H. Werkman, Allan Hemingway, and A. O. Nier J. Biol. Chem. 139, 365-376)
THE MECHANISM OF CARBON DIOXIDE FIXATION BY CELL-FREE EXTRACTS OF PIGEON LIVER: DISTRIBUTION OF LABELED CARBON DIOXIDE IN THE PRODUCTS (Harland G. Wood, Birgit Vennesland, and E. A. Evans, Jr. J. Biol. Chem. 159, 153-158)
THE FIXATION OF CARBON DIOXIDE IN OXALACETATE BY PIGEON LIVER (M. F. Utter and Harland G. Wood J. Biol. Chem. 164, 455-476)
J. Biol. Chem. 2005 280: e15. [Full Text]  


DNA: Replication, Repair, and Recombination:Back

Katrien Busschots, Jo Vercammen, Stéphane Emiliani, Richard Benarous, Yves Engelborghs, Frauke Christ, and Zeger Debyser
The Interaction of LEDGF/p75 with Integrase Is Lentivirus-specific and Promotes DNA Binding
J. Biol. Chem. 2005 280: 17841-17847. First Published on March 4, 2005; doi:10.1074/jbc.M411681200 [Abstract] [Full Text] [PDF]  

Landon Pastushok, Trevor F. Moraes, Michael J. Ellison, and Wei Xiao
A Single Mms2 "Key" Residue Insertion into a Ubc13 Pocket Determines the Interface Specificity of a Human Lys63 Ubiquitin Conjugation Complex
J. Biol. Chem. 2005 280: 17891-17900. First Published on March 4, 2005; doi:10.1074/jbc.M410469200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Jonathan E. Dodge, Masaki Okano, Fred Dick, Naomi Tsujimoto, Taiping Chen, Shumei Wang, Yoshihide Ueda, Nick Dyson, and En Li
Inactivation of Dnmt3b in Mouse Embryonic Fibroblasts Results in DNA Hypomethylation, Chromosomal Instability, and Spontaneous Immortalization
J. Biol. Chem. 2005 280: 17986-17991. First Published on March 8, 2005; doi:10.1074/jbc.M413246200 [Abstract] [Full Text] [PDF]  

Irina Bruck, Roxana E. Georgescu, and Mike O'Donnell
Conserved Interactions in the Staphylococcus aureus DNA PolC Chromosome Replication Machine
J. Biol. Chem. 2005 280: 18152-18162. First Published on January 12, 2005; doi:10.1074/jbc.M413595200 [Abstract] [Full Text] [PDF]  

Elena K. Braithwaite, Rajendra Prasad, David D. Shock, Esther W. Hou, William A. Beard, and Samuel H. Wilson
DNA Polymerase {lambda} Mediates a Back-up Base Excision Repair Activity in Extracts of Mouse Embryonic Fibroblasts
J. Biol. Chem. 2005 280: 18469-18475. First Published on March 3, 2005; doi:10.1074/jbc.M411864200 [Abstract] [Full Text] [PDF]  


Genes: Structure and Regulation:Back

Andrew J. Bannister, Robert Schneider, Fiona A. Myers, Alan W. Thorne, Colyn Crane-Robinson, and Tony Kouzarides
Spatial Distribution of Di- and Tri-methyl Lysine 36 of Histone H3 at Active Genes
J. Biol. Chem. 2005 280: 17732-17736. First Published on March 10, 2005; doi:10.1074/jbc.M500796200 [Abstract] [Full Text] [PDF]  

Sébastien Boni, Jean-Pierre Lavergne, Steeve Boulant, and Annie Cahour
Hepatitis C Virus Core Protein Acts as a trans-Modulating Factor on Internal Translation Initiation of the Viral RNA
J. Biol. Chem. 2005 280: 17737-17748. First Published on March 9, 2005; doi:10.1074/jbc.M501826200 [Abstract] [Full Text] [PDF]  

Roberto Rangel, Morgan R. McKeller, Jennifer C. Sims-Mourtada, Cristina Kashi, Kelly Cain, Eric D. Wieder, Jeffrey J. Molldrem, Lan V. Pham, Richard J. Ford, Patricia Yotnda, Christiane Guret, Véronique Francés, and Hector Martinez-Valdez
Assembly of the {kappa} PreB Receptor Requires a V{kappa}-like Protein Encoded by a Germline Transcript
J. Biol. Chem. 2005 280: 17807-17814. First Published on March 9, 2005; doi:10.1074/jbc.M409479200 [Abstract] [Full Text] [PDF] [Suppplemental Data]  

Sonja Baumli, Sabine Hoeppner, and Patrick Cramer
A Conserved Mediator Hinge Revealed in the Structure of the MED7·MED21 (Med7·Srb7) Heterodimer
J. Biol. Chem. 2005 280: 18171-18178. First Published on February 14, 2005; doi:10.1074/jbc.M413466200 [Abstract] [Full Text] [PDF]  

Baidehi Maiti, Jing Li, Alain de Bruin, Faye Gordon, Cynthia Timmers, Rene Opavsky, Kaustubha Patil, John Tuttle, Whitney Cleghorn, and Gustavo Leone
Cloning and Characterization of Mouse E2F8, a Novel Mammalian E2F Family Member Capable of Blocking Cellular Proliferation
J. Biol. Chem. 2005 280: 18211-18220. First Published on February 18, 2005; doi:10.1074/jbc.M501410200 [Abstract] [Full Text] [PDF]  

Babak Oskouian, Jane Mendel, Ellyn Shocron, Michael A. Lee, Jr., Henrik Fyrst, and Julie D. Saba
Regulation of Sphingosine-1-phosphate Lyase Gene Expression by Members of the GATA Family of Transcription Factors
J. Biol. Chem. 2005 280: 18403-18410. First Published on February 25, 2005; doi:10.1074/jbc.M410928200 [Abstract] [Full Text] [PDF]  

Hassan Sellak, ChungSik Choi, Natasha Browner, and Thomas M. Lincoln
Upstream Stimulatory Factors (USF-1/USF-2) Regulate Human cGMP-dependent Protein Kinase I Gene Expression in Vascular Smooth Muscle Cells
J. Biol. Chem. 2005 280: 18425-18433. First Published on February 28, 2005; doi:10.1074/jbc.M500775200 [Abstract] [Full Text] [PDF]  

Taishi Tsubouchi, Reiko Mineki, Hikari Taka, Naoko Kaga, Kimie Murayama, Chiharu Nishiyama, Hisakazu Yamane, Tomohisa Kuzuyama, and Makoto Nishiyama
Leader Peptide-mediated Transcriptional Attenuation of Lysine Biosynthetic Gene Cluster in Thermus thermophilus
J. Biol. Chem. 2005 280: 18511-18516. First Published on March 7, 2005; doi:10.1074/jbc.M414456200 [Abstract] [Full Text] [PDF]  

Baisong Liao, Yan Hu, David J. Herrick, and Gary Brewer
The RNA-binding Protein IMP-3 Is a Translational Activator of Insulin-like Growth Factor II Leader-3 mRNA during Proliferation of Human K562 Leukemia Cells
J. Biol. Chem. 2005 280: 18517-18524. First Published on March 7, 2005; doi:10.1074/jbc.M500270200 [Abstract] [Full Text] [PDF]  


RNA: Structure, Metabolism, and Catalysis:Back

Anita Changela, Alexandra Martins, Stewart Shuman, and Alfonso Mondragón
Crystal Structure of Baculovirus RNA Triphosphatase Complexed with Phosphate
J. Biol. Chem. 2005 280: 17848-17856. First Published on February 15, 2005; doi:10.1074/jbc.M500885200 [Abstract] [Full Text] [PDF]  


Protein Synthesis, Post-Translation Modification, and Degradation:Back

Rodion Demine and Peter Walden
Testing the Role of gp96 as Peptide Chaperone in Antigen Processing
J. Biol. Chem. 2005 280: 17573-17578. First Published on February 23, 2005; doi:10.1074/jbc.M501233200 [Abstract] [Full Text] [PDF]  

Shuhei Kotoshiba, Takumi Kamura, Taichi Hara, Noriko Ishida, and Keiichi I. Nakayama
Molecular Dissection of the Interaction between p27 and Kip1 Ubiquitylation-promoting Complex, the Ubiquitin Ligase That Regulates Proteolysis of p27 in G1 Phase
J. Biol. Chem. 2005 280: 17694-17700. First Published on March 3, 2005; doi:10.1074/jbc.M500866200 [Abstract] [Full Text] [PDF]  

Christine A. F. von Arnim, Ayae Kinoshita, Ithan D. Peltan, Michelle M. Tangredi, Lauren Herl, Bonny M. Lee, Robert Spoelgen, Tammy T. Hshieh, Sripriya Ranganathan, Frances D. Battey, Chun-Xiang Liu, Brian J. Bacskai, Sanja Sever, Michael C. Irizarry, Dudley K. Strickland, and Bradley T. Hyman
The Low Density Lipoprotein Receptor-related Protein (LRP) Is a Novel {beta}-Secretase (BACE1) Substrate
J. Biol. Chem. 2005 280: 17777-17785. First Published on March 4, 2005; doi:10.1074/jbc.M414248200 [Abstract] [Full Text] [PDF]  

Barbara Angeletti, Kevin J. Waldron, Katie B. Freeman, Hinayana Bawagan, Ishrut Hussain, Christopher C. J. Miller, Kwok-Fai Lau, Maria E. Tennant, Christopher Dennison, Nigel J. Robinson, and Colin Dingwall
BACE1 Cytoplasmic Domain Interacts with the Copper Chaperone for Superoxide Dismutase-1 and Binds Copper
J. Biol. Chem. 2005 280: 17930-17937. First Published on February 18, 2005; doi:10.1074/jbc.M412034200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Natasha Keith, Armando J. Parodi, and Julio J. Caramelo
Glycoprotein Tertiary and Quaternary Structures Are Monitored by the Same Quality Control Mechanism
J. Biol. Chem. 2005 280: 18138-18141. First Published on March 3, 2005; doi:10.1074/jbc.M501710200 [Abstract] [Full Text] [PDF]  

Agoston T. Agoston, Pedram Argani, Srinivasan Yegnasubramanian, Angelo M. De Marzo, Mohammad Ali Ansari-Lari, Jessica L. Hicks, Nancy E. Davidson, and William G. Nelson
Increased Protein Stability Causes DNA Methyltransferase 1 Dysregulation in Breast Cancer
J. Biol. Chem. 2005 280: 18302-18310. First Published on March 8, 2005; doi:10.1074/jbc.M501675200 [Abstract] [Full Text] [PDF]  

Olga V. Shpanchenko, Maria I. Zvereva, Pavel V. Ivanov, Elizaveta Y. Bugaeva, Alexey S. Rozov, Alexey A. Bogdanov, Markus Kalkum, Leif A. Isaksson, Knud H. Nierhaus, and Olga A. Dontsova
Stepping Transfer Messenger RNA through the Ribosome
J. Biol. Chem. 2005 280: 18368-18374. First Published on February 15, 2005; doi:10.1074/jbc.M409094200 [Abstract] [Full Text] [PDF]  

Toshihiro Obata and Yoshihiro Shiraiwa
A Novel Eukaryotic Selenoprotein in the Haptophyte Alga Emiliania huxleyi
J. Biol. Chem. 2005 280: 18462-18468. First Published on March 2, 2005; doi:10.1074/jbc.M501517200 [Abstract] [Full Text] [PDF]  

Catherine X. Moss, Stephen P. Matthews, Douglas J. Lamont, and Colin Watts
Asparagine Deamidation Perturbs Antigen Presentation on Class II Major Histocompatibility Complex Molecules
J. Biol. Chem. 2005 280: 18498-18503. First Published on March 4, 2005; doi:10.1074/jbc.M501241200 [Abstract] [Full Text] [PDF]  


Genomics, Proteomics, and Bioinformatics:Back

Kai Zhao, Mingzhu Liu, and Richard R. Burgess
The Global Transcriptional Response of Escherichia coli to Induced {sigma}32 Protein Involves {sigma}32 Regulon Activation Followed by Inactivation and Degradation of {sigma}32 in Vivo
J. Biol. Chem. 2005 280: 17758-17768. First Published on March 9, 2005; doi:10.1074/jbc.M500393200 [Abstract] [Full Text] [PDF]  


Protein Structure and Folding:Back

Gayathri Venkatraman, Aldrin V. Gomes, W. Glenn L. Kerrick, and James D. Potter
Characterization of Troponin T Dilated Cardiomyopathy Mutations in the Fetal Troponin Isoform
J. Biol. Chem. 2005 280: 17584-17592. First Published on December 28, 2004; doi:10.1074/jbc.M409337200 [Abstract] [Full Text] [PDF]  

Vivek S. Purohit, Karthik Ramani, Rita Sarkar, Haig H. Kazazian, Jr., and Sathyamangalam V. Balasubramanian
Lower Inhibitor Development in Hemophilia A Mice following Administration of Recombinant Factor VIII-O-Phospho-L-serine Complex
J. Biol. Chem. 2005 280: 17593-17600. First Published on February 23, 2005; doi:10.1074/jbc.M500163200 [Abstract] [Full Text] [PDF]  

Doug Huseby, Robin Lid Barklis, Ayna Alfadhli, and Eric Barklis
Assembly of Human Immunodeficiency Virus Precursor Gag Proteins
J. Biol. Chem. 2005 280: 17664-17670. First Published on February 25, 2005; doi:10.1074/jbc.M412325200 [Abstract] [Full Text] [PDF]  

Corina Wagner, Michael Russwurm, Ronald Jäger, Andreas Friebe, and Doris Koesling
Dimerization of Nitric Oxide-sensitive Guanylyl Cyclase Requires the {alpha}1 N Terminus
J. Biol. Chem. 2005 280: 17687-17693. First Published on March 3, 2005; doi:10.1074/jbc.M412099200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Tony Velkov, Sara Chuang, Jerome Wielens, Harry Sakellaris, William N. Charman, Christopher J. H. Porter, and Martin J. Scanlon
The Interaction of Lipophilic Drugs with Intestinal Fatty Acid-binding Protein
J. Biol. Chem. 2005 280: 17769-17776. First Published on February 18, 2005; doi:10.1074/jbc.M410193200 [Abstract] [Full Text] [PDF]  

Mia Ling, Ulrika Trollér, Ruth Zeidman, Helena Stensman, Anna Schultz, and Christer Larsson
Identification of Conserved Amino Acids N-terminal of the PKC{epsilon}C1b Domain Crucial for Protein Kinase C{epsilon}-mediated Induction of Neurite Outgrowth
J. Biol. Chem. 2005 280: 17910-17919. First Published on February 17, 2005; doi:10.1074/jbc.M412036200 [Abstract] [Full Text] [PDF]  

Christopher B. Marshall, Avijit Chakrabartty, and Peter L. Davies
Hyperactive Antifreeze Protein from Winter Flounder Is a Very Long Rod-like Dimer of {alpha}-Helices
J. Biol. Chem. 2005 280: 17920-17929. First Published on February 16, 2005; doi:10.1074/jbc.M500622200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Antonello Merlino, Lelio Mazzarella, Anna Carannante, Anna Di Fiore, Alberto Di Donato, Eugenio Notomista, and Filomena Sica
The Importance of Dynamic Effects on the Enzyme Activity: X-RAY STRUCTURE AND MOLECULAR DYNAMICS OF ONCONASE MUTANTS
J. Biol. Chem. 2005 280: 17953-17960. First Published on February 22, 2005; doi:10.1074/jbc.M501339200 [Abstract] [Full Text] [PDF]  

Juan Reguera, Esther Grueso, Aura Carreira, Cristina Sánchez-Martínez, José M. Almendral, and Mauricio G. Mateu
Functional Relevance of Amino Acid Residues Involved in Interactions with Ordered Nucleic Acid in a Spherical Virus
J. Biol. Chem. 2005 280: 17969-17977. First Published on February 23, 2005; doi:10.1074/jbc.M500867200 [Abstract] [Full Text] [PDF]  

Marcia Alvarez-Fernandez, Yu-He Liang, Magnus Abrahamson, and Xiao-Dong Su
Crystal Structure of Human Cystatin D, a Cysteine Peptidase Inhibitor with Restricted Inhibition Profile
J. Biol. Chem. 2005 280: 18221-18228. First Published on February 23, 2005; doi:10.1074/jbc.M411914200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Kamel El Omari, Louise E. Bird, Charles E. Nichols, Jingshan Ren, and David K. Stammers
Crystal Structure of CC3 (TIP30): IMPLICATIONS FOR ITS ROLE AS A TUMOR SUPPRESSOR
J. Biol. Chem. 2005 280: 18229-18236. First Published on February 22, 2005; doi:10.1074/jbc.M501113200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Thierry C. Aupérin, Gilles R. Bolduc, Miriam J. Baron, Annie Heroux, David J. Filman, Lawrence C. Madoff, and James M. Hogle
Crystal Structure of the N-terminal Domain of the Group B Streptococcus Alpha C Protein
J. Biol. Chem. 2005 280: 18245-18252. First Published on March 6, 2005; doi:10.1074/jbc.M412391200 [Abstract] [Full Text] [PDF]  

Dong Hae Shin, Natalia Oganesyan, Jaru Jancarik, Hisao Yokota, Rosalind Kim, and Sung-Hou Kim
Crystal Structure of a Nicotinate Phosphoribosyltransferase from Thermoplasma acidophilum
J. Biol. Chem. 2005 280: 18326-18335. First Published on March 6, 2005; doi:10.1074/jbc.M501622200 [Abstract] [Full Text] [PDF]  


Enzyme Catalysis and Regulation:Back

Rajasekhar Neeli, Olivier Roitel, Nigel S. Scrutton, and Andrew W. Munro
Switching Pyridine Nucleotide Specificity in P450 BM3: MECHANISTIC ANALYSIS OF THE W1046H AND W1046A ENZYMES
J. Biol. Chem. 2005 280: 17634-17644. First Published on February 14, 2005; doi:10.1074/jbc.M413826200 [Abstract] [Full Text] [PDF]  

Eun Suk Song, Abigail Daily, Michael G. Fried, Maria Aparecida Juliano, Luiz Juliano, and Louis B. Hersh
Mutation of Active Site Residues of Insulin-degrading Enzyme Alters Allosteric Interactions
J. Biol. Chem. 2005 280: 17701-17706. First Published on March 3, 2005; doi:10.1074/jbc.M501896200 [Abstract] [Full Text] [PDF]  

Hemachand Tummala, Cheolwha Jung, Ashutosh Tiwari, Cynthia M. J. Higgins, Lawrence J. Hayward, and Zuoshang Xu
Inhibition of Chaperone Activity Is a Shared Property of Several Cu,Zn-Superoxide Dismutase Mutants That Cause Amyotrophic Lateral Sclerosis
J. Biol. Chem. 2005 280: 17725-17731. First Published on March 7, 2005; doi:10.1074/jbc.M501705200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Zanna Beharry and Timothy Palzkill
Functional Analysis of Active Site Residues of the Fosfomycin Resistance Enzyme FosA from Pseudomonas aeruginosa
J. Biol. Chem. 2005 280: 17786-17791. First Published on March 1, 2005; doi:10.1074/jbc.M501052200 [Abstract] [Full Text] [PDF]  

Amy S. Espeseth, Min Xu, Qian Huang, Craig A. Coburn, Kristen L. G. Jones, Marc Ferrer, Paul D. Zuck, Berta Strulovici, Eric A. Price, Guoxin Wu, Abigail L. Wolfe, Janet E. Lineberger, Mohinder Sardana, Katherine Tugusheva, Beth L. Pietrak, Ming-Chih Crouthamel, Ming-Tain Lai, Elizabeth Chen Dodson, Renzo Bazzo, Xiao-Ping Shi, Adam J. Simon, Yueming Li, and Daria J. Hazuda
Compounds That Bind APP and Inhibit A{beta} Processing in Vitro Suggest a Novel Approach to Alzheimer Disease Therapeutics
J. Biol. Chem. 2005 280: 17792-17797. First Published on February 25, 2005; doi:10.1074/jbc.M414331200 [Abstract] [Full Text] [PDF]  

Xiang-dong Li, Reiko Ikebe, and Mitsuo Ikebe
Activation of Myosin Va Function by Melanophilin, a Specific Docking Partner of Myosin Va
J. Biol. Chem. 2005 280: 17815-17822. First Published on March 9, 2005; doi:10.1074/jbc.M413295200 [Abstract] [Full Text] [PDF]  

Oliver Schilling, Bettina Späth, Brenda Kostelecky, Anita Marchfelder, Wolfram Meyer-Klaucke, and Andreas Vogel
Exosite Modules Guide Substrate Recognition in the ZiPD/ElaC Protein Family
J. Biol. Chem. 2005 280: 17857-17862. First Published on February 7, 2005; doi:10.1074/jbc.M500591200 [Abstract] [Full Text] [PDF]  

Lawrence de Garavilla, Michael N. Greco, Narayanasami Sukumar, Zhi-Wei Chen, Agustin O. Pineda, F. Scott Mathews, Enrico Di Cera, Edward C. Giardino, Grace I. Wells, Barbara J. Haertlein, Jack A. Kauffman, Thomas W. Corcoran, Claudia K. Derian, Annette J. Eckardt, Bruce P. Damiano, Patricia Andrade-Gordon, and Bruce E. Maryanoff
A Novel, Potent Dual Inhibitor of the Leukocyte Proteases Cathepsin G and Chymase: MOLECULAR MECHANISMS AND ANTI-INFLAMMATORY ACTIVITY IN VIVO
J. Biol. Chem. 2005 280: 18001-18007. First Published on February 28, 2005; doi:10.1074/jbc.M501302200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Magne Olufsen, Arne O. Smalås, Elin Moe, and Bjørn O. Brandsdal
Increased Flexibility as a Strategy for Cold Adaptation: A COMPARATIVE MOLECULAR DYNAMICS STUDY OF COLD- AND WARM-ACTIVE URACIL DNA GLYCOSYLASE
J. Biol. Chem. 2005 280: 18042-18048. First Published on March 3, 2005; doi:10.1074/jbc.M500948200 [Abstract] [Full Text] [PDF]  

Bichitra K. Biswal, Maia M. Cherney, Meitian Wang, Laval Chan, Constantin G. Yannopoulos, Darius Bilimoria, Olivier Nicolas, Jean Bedard, and Michael N. G. James
Crystal Structures of the RNA-dependent RNA Polymerase Genotype 2a of Hepatitis C Virus Reveal Two Conformations and Suggest Mechanisms of Inhibition by Non-nucleoside Inhibitors
J. Biol. Chem. 2005 280: 18202-18210. First Published on March 2, 2005; doi:10.1074/jbc.M413410200 [Abstract] [Full Text] [PDF]  

Vipender Singh, Gary B. Evans, Dirk H. Lenz, Jennifer M. Mason, Keith Clinch, Simon Mee, Gavin F. Painter, Peter C. Tyler, Richard H. Furneaux, Jeffrey E. Lee, P. Lynne Howell, and Vern L. Schramm
Femtomolar Transition State Analogue Inhibitors of 5'-Methylthioadenosine/S-Adenosylhomocysteine Nucleosidase from Escherichia coli
J. Biol. Chem. 2005 280: 18265-18273. First Published on March 4, 2005; doi:10.1074/jbc.M414472200 [Abstract] [Full Text] [PDF]  

Jeffrey E. Lee, Vipender Singh, Gary B. Evans, Peter C. Tyler, Richard H. Furneaux, Kenneth A. Cornell, Michael K. Riscoe, Vern L. Schramm, and P. Lynne Howell
Structural Rationale for the Affinity of Pico- and Femtomolar Transition State Analogues of Escherichia coli 5'-Methylthioadenosine/S-Adenosylhomocysteine Nucleosidase
J. Biol. Chem. 2005 280: 18274-18282. First Published on March 3, 2005; doi:10.1074/jbc.M414471200 [Abstract] [Full Text] [PDF] [Summary]  

Christoph Bächler, Karin Flükiger-Brühwiler, Philipp Schneider, Priska Bähler, and Bernhard Erni
From ATP as Substrate to ADP as Coenzyme: FUNCTIONAL EVOLUTION OF THE NUCLEOTIDE BINDING SUBUNIT OF DIHYDROXYACETONE KINASES
J. Biol. Chem. 2005 280: 18321-18325. First Published on March 7, 2005; doi:10.1074/jbc.M500279200 [Abstract] [Full Text] [PDF]  

Keiji Nogami, Qian Zhou, Timothy Myles, Lawrence L. K. Leung, Hironao Wakabayashi, and Philip J. Fay
Exosite-interactive Regions in the A1 and A2 Domains of Factor VIII Facilitate Thrombin-catalyzed Cleavage of Heavy Chain
J. Biol. Chem. 2005 280: 18476-18487. First Published on March 3, 2005; doi:10.1074/jbc.M412778200 [Abstract] [Full Text] [PDF]  


Metabolism and Bioenergetics:Back

Daniel Smith, Jimmy Gray, Larkin Mitchell, William E. Antholine, and Jonathan P. Hosler
Assembly of Cytochrome-c Oxidase in the Absence of Assembly Protein Surf1p Leads to Loss of the Active Site Heme
J. Biol. Chem. 2005 280: 17652-17656. First Published on March 11, 2005; doi:10.1074/jbc.C500061200 [Abstract] [Full Text] [PDF]  

Itzhak Nissim, Bohdan Luhovyy, Oksana Horyn, Yevgeny Daikhin, Ilana Nissim, and Marc Yudkoff
The Role of Mitochondrially Bound Arginase in the Regulation of Urea Synthesis: STUDIES WITH [U-15N4]ARGININE, ISOLATED MITOCHONDRIA, AND PERFUSED RAT LIVER
J. Biol. Chem. 2005 280: 17715-17724. First Published on March 7, 2005; doi:10.1074/jbc.M500607200 [Abstract] [Full Text] [PDF]  

Takahito Nomura, Tetsuo Kushiro, Takao Yokota, Yuji Kamiya, Gerard J. Bishop, and Shinjiro Yamaguchi
The Last Reaction Producing Brassinolide Is Catalyzed by Cytochrome P-450s, CYP85A3 in Tomato and CYP85A2 in Arabidopsis
J. Biol. Chem. 2005 280: 17873-17879. First Published on February 14, 2005; doi:10.1074/jbc.M414592200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Aimin Xu, Kok Weng Chan, Ruby L. C. Hoo, Yu Wang, Kathryn C. B. Tan, Jialiang Zhang, Baoying Chen, Michael C. Lam, Cynthia Tse, Garth J. S. Cooper, and Karen S. L. Lam
Testosterone Selectively Reduces the High Molecular Weight Form of Adiponectin by Inhibiting Its Secretion from Adipocytes
J. Biol. Chem. 2005 280: 18073-18080. First Published on March 9, 2005; doi:10.1074/jbc.M414231200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Michelle Lane and David K. Gardner
Mitochondrial Malate-Aspartate Shuttle Regulates Mouse Embryo Nutrient Consumption
J. Biol. Chem. 2005 280: 18361-18367. First Published on January 19, 2005; doi:10.1074/jbc.M500174200 [Abstract] [Full Text] [PDF]  

Linnka Lefebvre-Legendre, Bénédicte Salin, Jacques Schaëffer, Daniel Brèthes, Alain Dautant, Sharon H. Ackerman, and Jean-Paul di Rago
Failure to Assemble the {alpha}3 {beta}3 Subcomplex of the ATP Synthase Leads to Accumulation of the {alpha} and {beta} Subunits within Inclusion Bodies and the Loss of Mitochondrial Cristae in Saccharomyces cerevisiae
J. Biol. Chem. 2005 280: 18386-18392. First Published on February 16, 2005; doi:10.1074/jbc.M410789200 [Abstract] [Full Text] [PDF]  

Jason Callio, Tim D. Oury, and Charleen T. Chu
Manganese Superoxide Dismutase Protects against 6-Hydroxydopamine Injury in Mouse Brains
J. Biol. Chem. 2005 280: 18536-18542. First Published on March 8, 2005; doi:10.1074/jbc.M413224200 [Abstract] [Full Text] [PDF]  


Glycobiology and Extracellular Matrices:Back

Ningguo Gao, Jie Shang, and Mark A. Lehrman
Analysis of Glycosylation in CDG-Ia Fibroblasts by Fluorophore-assisted Carbohydrate Electrophoresis: IMPLICATIONS FOR EXTRACELLULAR GLUCOSE AND INTRACELLULAR MANNOSE 6-PHOSPHATE
J. Biol. Chem. 2005 280: 17901-17909. First Published on February 11, 2005; doi:10.1074/jbc.M500510200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Keiko Fukushima, Yukio Ikehara, and Katsuko Yamashita
Functional Role Played by the Glycosylphosphatidylinositol Anchor Glycan of CD48 in Interleukin-18-induced Interferon-{gamma} Production
J. Biol. Chem. 2005 280: 18056-18062. First Published on March 10, 2005; doi:10.1074/jbc.M413297200 [Abstract] [Full Text] [PDF]  

Charles D. Blundell, Andrew Almond, David J. Mahoney, Paul L. DeAngelis, Iain D. Campbell, and Anthony J. Day
Towards a Structure for a TSG-6·Hyaluronan Complex by Modeling and NMR Spectroscopy: INSIGHTS INTO OTHER MEMBERS OF THE LINK MODULE SUPERFAMILY
J. Biol. Chem. 2005 280: 18189-18201. First Published on February 17, 2005; doi:10.1074/jbc.M414343200 [Abstract] [Full Text] [PDF] [Supplemental Data]  


Lipids and Lipoproteins:Back

Jean-Paul F. Morand, Joseph Macri, and Khosrow Adeli
Proteomic Profiling of Hepatic Endoplasmic Reticulum-associated Proteins in an Animal Model of Insulin Resistance and Metabolic Dyslipidemia
J. Biol. Chem. 2005 280: 17626-17633. First Published on March 9, 2005; doi:10.1074/jbc.M413343200 [Abstract] [Full Text] [PDF]  

Isabelle Billault, Jia-Rong Duan, Sébastien Guiet, and Richard J. Robins
Quantitative Deuterium Isotopic Profiling at Natural Abundance Indicates Mechanistic Differences for {Delta}12-Epoxidase and {Delta}12-Desaturase in Vernonia galamensis
J. Biol. Chem. 2005 280: 17645-17651. First Published on February 18, 2005; doi:10.1074/jbc.M500909200 [Abstract] [Full Text] [PDF]  

Fabien Alpy, Vinoth K. Latchumanan, Valérie Kedinger, Agnes Janoshazi, Christoph Thiele, Corinne Wendling, Marie-Christine Rio, and Catherine Tomasetto
Functional Characterization of the MENTAL Domain
J. Biol. Chem. 2005 280: 17945-17952. First Published on February 17, 2005; doi:10.1074/jbc.M500723200 [Abstract] [Full Text] [PDF]  

Takafumi Kobayashi, Hiromu Takematsu, Toshiyuki Yamaji, Shinsuke Hiramoto, and Yasunori Kozutsumi
Disturbance of Sphingolipid Biosynthesis Abrogates the Signaling of Mss4, Phosphatidylinositol-4-phosphate 5-Kinase, in Yeast
J. Biol. Chem. 2005 280: 18087-18094. First Published on March 1, 2005; doi:10.1074/jbc.M414138200 [Abstract] [Full Text] [PDF]  

Xian-Cheng Jiang, Zhiqiang Li, Ruijie Liu, Xiao Ping Yang, Meihui Pan, Laurent Lagrost, Edward A. Fisher, and Kevin Jon Williams
Phospholipid Transfer Protein Deficiency Impairs Apolipoprotein-B Secretion from Hepatocytes by Stimulating a Proteolytic Pathway through a Relative Deficiency of Vitamin E and an Increase in Intracellular Oxidants
J. Biol. Chem. 2005 280: 18336-18340. First Published on February 25, 2005; doi:10.1074/jbc.M500007200 [Abstract] [Full Text] [PDF]  

Saori Oka, Shin Yanagimoto, Shinobu Ikeda, Maiko Gokoh, Seishi Kishimoto, Keizo Waku, Yoshio Ishima, and Takayuki Sugiura
Evidence for the Involvement of the Cannabinoid CB2 Receptor and Its Endogenous Ligand 2-Arachidonoylglycerol in 12-O-Tetradecanoylphorbol-13-acetate-induced Acute Inflammation in Mouse Ear
J. Biol. Chem. 2005 280: 18488-18497. First Published on March 4, 2005; doi:10.1074/jbc.M413260200 [Abstract] [Full Text] [PDF]  


Membrane Transport, Structure, Function, and Biogenesis:Back

Suming Hua, Cheng Xu, Hailun Ma, and Giuseppe Inesi
Interference with Phosphoenzyme Isomerization and Inhibition of the Sarco-endoplasmic Reticulum Ca2+ ATPase by 1,3-Dibromo-2,4,6-tris(methylisothiouronium) Benzene
J. Biol. Chem. 2005 280: 17579-17583. First Published on March 3, 2005; doi:10.1074/jbc.M500472200 [Abstract] [Full Text] [PDF]  

Marcelo D. Carattino, Robert S. Edinger, Heather J. Grieser, Rosalee Wise, Dietbert Neumann, Uwe Schlattner, John P. Johnson, Thomas R. Kleyman, and Kenneth R. Hallows
Epithelial Sodium Channel Inhibition by AMP-activated Protein Kinase in Oocytes and Polarized Renal Epithelial Cells
J. Biol. Chem. 2005 280: 17608-17616. First Published on March 7, 2005; doi:10.1074/jbc.M501770200 [Abstract] [Full Text] [PDF]  

Angelita Tottene, Francesca Pivotto, Tommaso Fellin, Tiziana Cesetti, Arn M. J. M. van den Maagdenberg, and Daniela Pietrobon
Specific Kinetic Alterations of Human CaV2.1 Calcium Channels Produced by Mutation S218L Causing Familial Hemiplegic Migraine and Delayed Cerebral Edema and Coma after Minor Head Trauma
J. Biol. Chem. 2005 280: 17678-17686. First Published on March 2, 2005; doi:10.1074/jbc.M501110200 [Abstract] [Full Text] [PDF]  

Deborah S. Cooper, Nina C. Saxena, Han Soo Yang, Hye Jeong Lee, Anisha G. Moring, Amy Lee, and Inyeong Choi
Molecular and Functional Characterization of the Electroneutral Na/HCO3 Cotransporter NBCn1 in Rat Hippocampal Neurons
J. Biol. Chem. 2005 280: 17823-17830. First Published on February 17, 2005; doi:10.1074/jbc.M408646200 [Abstract] [Full Text] [PDF]  

Emily R. Slepkov, Jan K. Rainey, Xiuju Li, Yongsheng Liu, Florence J. Cheng, Darrin A. Lindhout, Brian D. Sykes, and Larry Fliegel
Structural and Functional Characterization of Transmembrane Segment IV of the NHE1 Isoform of the Na+/H+ Exchanger
J. Biol. Chem. 2005 280: 17863-17872. First Published on January 26, 2005; doi:10.1074/jbc.M409608200 [Abstract] [Full Text] [PDF]  

Nicola Ray, Anja Nenninger, Conrad W. Mullineaux, and Colin Robinson
Location and Mobility of Twin Arginine Translocase Subunits in the Escherichia coli Plasma Membrane
J. Biol. Chem. 2005 280: 17961-17968. First Published on February 23, 2005; doi:10.1074/jbc.M413521200 [Abstract] [Full Text] [PDF]  

Michaela Leroch, Simon Kirchberger, Ilka Haferkamp, Markus Wahl, H. Ekkehard Neuhaus, and Joachim Tjaden
Identification and Characterization of a Novel Plastidic Adenine Nucleotide Uniporter from Solanum tuberosum
J. Biol. Chem. 2005 280: 17992-18000. First Published on February 28, 2005; doi:10.1074/jbc.M412462200 [Abstract] [Full Text] [PDF]  

David L. Stokes, Franck Delavoie, William J. Rice, Philippe Champeil, David B. McIntosh, and Jean-Jacques Lacapère
Structural Studies of a Stabilized Phosphoenzyme Intermediate of Ca2+-ATPase
J. Biol. Chem. 2005 280: 18063-18072. First Published on February 25, 2005; doi:10.1074/jbc.M500031200 [Abstract] [Full Text] [PDF]  

Marco Caprini, Marianna Fava, Pierluigi Valente, Gregorio Fernandez-Ballester, Carmela Rapisarda, Stefano Ferroni, and Antonio Ferrer-Montiel
Molecular Compatibility of the Channel Gate and the N Terminus of S5 Segment for Voltage-gated Channel Activity
J. Biol. Chem. 2005 280: 18253-18264. First Published on March 4, 2005; doi:10.1074/jbc.M413389200 [Abstract] [Full Text] [PDF]  

Takahiro Yamada, Andrew R. Carson, Isabella Caniggia, Kyohei Umebayashi, Tamotsu Yoshimori, Kazuhiko Nakabayashi, and Stephen W. Scherer
Endothelial Nitric-oxide Synthase Antisense (NOS3AS) Gene Encodes an Autophagy-related Protein (APG9-like2) Highly Expressed in Trophoblast
J. Biol. Chem. 2005 280: 18283-18290. First Published on March 8, 2005; doi:10.1074/jbc.M413957200 [Abstract] [Full Text] [PDF]  

Maria Füzesi, Kay-Eberhard Gottschalk, Moshit Lindzen, Alla Shainskaya, Bernhard Küster, Haim Garty, and Steven J. D. Karlish
Covalent Cross-links between the {gamma} Subunit (FXYD2) and {alpha} and {beta} Subunits of Na,K-ATPase: MODELING THE {alpha}-{gamma} INTERACTION
J. Biol. Chem. 2005 280: 18291-18301. First Published on March 2, 2005; doi:10.1074/jbc.M500080200 [Abstract] [Full Text] [PDF]  

Tamara Darsow, T. K. Booker, Juan Carlos Piña-Crespo, and Stephen F. Heinemann
Exocytic Trafficking Is Required for Nicotine-induced Up-regulation of {alpha}4{beta}2 Nicotinic Acetylcholine Receptors
J. Biol. Chem. 2005 280: 18311-18320. First Published on March 1, 2005; doi:10.1074/jbc.M501157200 [Abstract] [Full Text] [PDF]  

Kenneth A. Volk, Russell F. Husted, Rita D. Sigmund, and John B. Stokes
Overexpression of the Epithelial Na+ Channel {gamma} Subunit in Collecting Duct Cells: INTERACTIONS OF LIDDLE'S MUTATIONS AND STEROIDS ON EXPRESSION AND FUNCTION
J. Biol. Chem. 2005 280: 18348-18354. First Published on March 8, 2005; doi:10.1074/jbc.M413689200 [Abstract] [Full Text] [PDF]  

Margaret A. Owegi, Anne L. Carenbauer, Nicole M. Wick, Jamie F. Brown, Kari L. Terhune, Sarah A. Bilbo, Rebecca S. Weaver, Rebecca Shircliff, Natalia Newcomb, and Karlett J. Parra-Belky
Mutational Analysis of the Stator Subunit E of the Yeast V-ATPase
J. Biol. Chem. 2005 280: 18393-18402. First Published on February 17, 2005; doi:10.1074/jbc.M412567200 [Abstract] [Full Text] [PDF]  

Malik Lutzmann, Ruth Kunze, Karin Stangl, Philipp Stelter, Katalin Fejes Tóth, Bettina Böttcher, and Ed Hurt
Reconstitution of Nup157 and Nup145N into the Nup84 Complex
J. Biol. Chem. 2005 280: 18442-18451. First Published on March 1, 2005; doi:10.1074/jbc.M412787200 [Abstract] [Full Text] [PDF] [Supplemental Data]  


Mechanisms Of Signal Transduction:Back

Preeti Subramanian, Robert V. Stahelin, Zdzislaw Szulc, Alicja Bielawska, Wonhwa Cho, and Charles E. Chalfant
Ceramide 1-Phosphate Acts as a Positive Allosteric Activator of Group IVA Cytosolic Phospholipase A2{alpha} and Enhances the Interaction of the Enzyme with Phosphatidylcholine
J. Biol. Chem. 2005 280: 17601-17607. First Published on March 1, 2005; doi:10.1074/jbc.M414173200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Shibani Mukherjee and Susan E. Conrad
c-Myc Suppresses p21WAF1/CIP1 Expression during Estrogen Signaling and Antiestrogen Resistance in Human Breast Cancer Cells
J. Biol. Chem. 2005 280: 17617-17625. First Published on March 8, 2005; doi:10.1074/jbc.M502278200 [Abstract] [Full Text] [PDF]  

Rebecca Ley, Kathryn Hadfield, Elizabeth Howes, and Simon J. Cook
Identification of a DEF-type Docking Domain for Extracellular Signal-regulated Kinases 1/2 That Directs Phosphorylation and Turnover of the BH3-only Protein BimEL
J. Biol. Chem. 2005 280: 17657-17663. First Published on February 23, 2005; doi:10.1074/jbc.M412342200 [Abstract] [Full Text] [PDF]  

Alexandre Caillaud, Ara G. Hovanessian, David E. Levy, and Isabelle J. Marié
Regulatory Serine Residues Mediate Phosphorylation-dependent and Phosphorylation-independent Activation of Interferon Regulatory Factor 7
J. Biol. Chem. 2005 280: 17671-17677. First Published on March 2, 2005; doi:10.1074/jbc.M411389200 [Abstract] [Full Text] [PDF]  

Chundong Yu, Fen Wang, Chengliu Jin, Xinqiang Huang, and Wallace L. McKeehan
Independent Repression of Bile Acid Synthesis and Activation of c-Jun N-terminal Kinase (JNK) by Activated Hepatocyte Fibroblast Growth Factor Receptor 4 (FGFR4) and Bile Acids
J. Biol. Chem. 2005 280: 17707-17714. First Published on March 4, 2005; doi:10.1074/jbc.M411771200 [Abstract] [Full Text] [PDF]  

Carla M. Pedrosa Ribeiro, Anthony M. Paradiso, Ute Schwab, Juan Perez-Vilar, Lisa Jones, Wanda O'Neal, and Richard C. Boucher
Chronic Airway Infection/Inflammation Induces a Ca2+i-dependent Hyperinflammatory Response in Human Cystic Fibrosis Airway Epithelia
J. Biol. Chem. 2005 280: 17798-17806. First Published on March 3, 2005; doi:10.1074/jbc.M410618200 [Abstract] [Full Text] [PDF]  

Adrian Higginbottom, Stuart A. Cain, Trent M. Woodruff, Lavinia M. Proctor, Praveen K. Madala, Joel D. A. Tyndall, Stephen M. Taylor, David P. Fairlie, and Peter N. Monk
Comparative Agonist/Antagonist Responses in Mutant Human C5a Receptors Define the Ligand Binding Site
J. Biol. Chem. 2005 280: 17831-17840. First Published on January 20, 2005; doi:10.1074/jbc.M410797200 [Abstract] [Full Text] [PDF]  

Jérôme N. Feige, Laurent Gelman, Cicerone Tudor, Yves Engelborghs, Walter Wahli, and Béatrice Desvergne
Fluorescence Imaging Reveals the Nuclear Behavior of Peroxisome Proliferator-activated Receptor/Retinoid X Receptor Heterodimers in the Absence and Presence of Ligand
J. Biol. Chem. 2005 280: 17880-17890. First Published on February 24, 2005; doi:10.1074/jbc.M500786200 [Abstract] [Full Text] [PDF] [Summary]  

Karim El Bakkouri, Andy Wullaert, Mira Haegman, Karen Heyninck, and Rudi Beyaert
Adenoviral Gene Transfer of the NF-{kappa}B Inhibitory Protein ABIN-1 Decreases Allergic Airway Inflammation in a Murine Asthma Model
J. Biol. Chem. 2005 280: 17938-17944. First Published on February 18, 2005; doi:10.1074/jbc.M413588200 [Abstract] [Full Text] [PDF]  

Craig A. Eyster, Quwanza S. Duggins, and Ann Louise Olson
Expression of Constitutively Active Akt/Protein Kinase B Signals GLUT4 Translocation in the Absence of an Intact Actin Cytoskeleton
J. Biol. Chem. 2005 280: 17978-17985. First Published on February 28, 2005; doi:10.1074/jbc.M409806200 [Abstract] [Full Text] [PDF]  

Masanori Osawa, Alexandra Dace, Kit I. Tong, Aswani Valiveti, Mitsuhiko Ikura, and James B. Ames
Mg2+ and Ca2+ Differentially Regulate DNA Binding and Dimerization of DREAM
J. Biol. Chem. 2005 280: 18008-18014. First Published on March 3, 2005; doi:10.1074/jbc.M500338200 [Abstract] [Full Text] [PDF]  

Emma C. Josefsson, Harry H. Gebhard, Thomas P. Stossel, John H. Hartwig, and Karin M. Hoffmeister
The Macrophage {alpha}M{beta}2 Integrin {alpha}M Lectin Domain Mediates the Phagocytosis of Chilled Platelets
J. Biol. Chem. 2005 280: 18025-18032. First Published on March 1, 2005; doi:10.1074/jbc.M501178200 [Abstract] [Full Text] [PDF]  

Thomas E. Meigs, Juhi Juneja, C. Todd DeMarco, Laura N. Stemmle, Daniel D. Kaplan, and Patrick J. Casey
Selective Uncoupling of G{alpha}12 from Rho-mediated Signaling
J. Biol. Chem. 2005 280: 18049-18055. First Published on March 3, 2005; doi:10.1074/jbc.M500445200 [Abstract] [Full Text] [PDF]  

Qin Wei and Yong Xia
Roles of 3-Phosphoinositide-dependent Kinase 1 in the Regulation of Endothelial Nitric-oxide Synthase Phosphorylation and Function by Heat Shock Protein 90
J. Biol. Chem. 2005 280: 18081-18086. First Published on February 28, 2005; doi:10.1074/jbc.M413607200 [Abstract] [Full Text] [PDF]  

Jim Boulanger, Anne Vézina, Sébastien Mongrain, Francois Boudreau, Nathalie Perreault, Benoît A. Auclair, Jean Lainé, Claude Asselin, and Nathalie Rivard
Cdk2-dependent Phosphorylation of Homeobox Transcription Factor CDX2 Regulates Its Nuclear Translocation and Proteasome-mediated Degradation in Human Intestinal Epithelial Cells
J. Biol. Chem. 2005 280: 18095-18107. First Published on February 28, 2005; doi:10.1074/jbc.M502184200 [Abstract] [Full Text] [PDF]  

Rajesh R. Singh, Chunying Song, Zhibo Yang, and Rakesh Kumar
Nuclear Localization and Chromatin Targets of p21-activated Kinase 1
J. Biol. Chem. 2005 280: 18130-18137. First Published on March 3, 2005; doi:10.1074/jbc.M412607200 [Abstract] [Full Text] [PDF]  

Zi-Zhen Wu, Shao-Rui Chen, and Hui-Lin Pan
Transient Receptor Potential Vanilloid Type 1 Activation Down-regulates Voltage-gated Calcium Channels through Calcium-dependent Calcineurin in Sensory Neurons
J. Biol. Chem. 2005 280: 18142-18151. First Published on March 3, 2005; doi:10.1074/jbc.M501229200 [Abstract] [Full Text] [PDF]  

Wenming Li, Rongbiao Pi, Hugh H. N. Chan, Hongjun Fu, Nelson T. K. Lee, Hing Wai Tsang, Yongmei Pu, Donald C. Chang, Chaoying Li, Jialie Luo, Keming Xiong, Zhiwang Li, Hong Xue, Paul R. Carlier, Yuanping Pang, Karl W. K. Tsim, Mingtao Li, and Yifan Han
Novel Dimeric Acetylcholinesterase Inhibitor Bis(7)-tacrine, but Not Donepezil, Prevents Glutamate-induced Neuronal Apoptosis by Blocking N-Methyl-D-aspartate Receptors
J. Biol. Chem. 2005 280: 18179-18188. First Published on February 14, 2005; doi:10.1074/jbc.M411085200 [Abstract] [Full Text] [PDF]  

Shin-ichiro Miura, Sadashiva S. Karnik, and Keijiro Saku
Constitutively Active Homo-oligomeric Angiotensin II Type 2 Receptor Induces Cell Signaling Independent of Receptor Conformation and Ligand Stimulation
J. Biol. Chem. 2005 280: 18237-18244. First Published on March 3, 2005; doi:10.1074/jbc.M500639200 [Abstract] [Full Text] [PDF]  

Yoko Obata, Kazuo Yamamoto, Masanobu Miyazaki, Kunitada Shimotohno, Shigeru Kohno, and Toshifumi Matsuyama
Role of Cyclophilin B in Activation of Interferon Regulatory Factor-3
J. Biol. Chem. 2005 280: 18355-18360. First Published on March 10, 2005; doi:10.1074/jbc.M501684200 [Abstract] [Full Text] [PDF]  

Brian J. Conti, Beckley K. Davis, Jinghua Zhang, William O'Connor, Jr., Kristi L. Williams, and Jenny P.-Y. Ting
CATERPILLER 16.2 (CLR16.2), a Novel NBD/LRR Family Member That Negatively Regulates T Cell Function
J. Biol. Chem. 2005 280: 18375-18385. First Published on February 10, 2005; doi:10.1074/jbc.M413169200 [Abstract] [Full Text] [PDF]  

Katarzyna A. Cieslik, Ying Zhu, Mikhail Shtivelband, and Kenneth K. Wu
Inhibition of p90 Ribosomal S6 Kinase-mediated CCAAT/Enhancer-binding Protein {beta} Activation and Cyclooxygenase-2 Expression by Salicylate
J. Biol. Chem. 2005 280: 18411-18417. First Published on February 28, 2005; doi:10.1074/jbc.M410017200 [Abstract] [Full Text] [PDF]  

Amane Harada, Hironori Katoh, and Manabu Negishi
Direct Interaction of Rnd1 with FRS2{beta} Regulates Rnd1-induced Down-regulation of RhoA Activity and Is Involved in Fibroblast Growth Factor-induced Neurite Outgrowth in PC12 Cells
J. Biol. Chem. 2005 280: 18418-18424. First Published on February 28, 2005; doi:10.1074/jbc.M411356200 [Abstract] [Full Text] [PDF]  

Motohiro Nishida, Shihori Tanabe, Yoshiko Maruyama, Supachoke Mangmool, Kyoji Urayama, Yuichi Nagamatsu, Shuichi Takagahara, Justin H. Turner, Tohru Kozasa, Hiroyuki Kobayashi, Yoji Sato, Toru Kawanishi, Ryuji Inoue, Taku Nagao, and Hitoshi Kurose
G{alpha}12/13- and Reactive Oxygen Species-dependent Activation of c-Jun NH2-terminal Kinase and p38 Mitogen-activated Protein Kinase by Angiotensin Receptor Stimulation in Rat Neonatal Cardiomyocytes
J. Biol. Chem. 2005 280: 18434-18441. First Published on March 1, 2005; doi:10.1074/jbc.M409710200 [Abstract] [Full Text] [PDF]  

Ko Fujimori, Keiichi Kadoyama, and Yoshihiro Urade
Protein Kinase C Activates Human Lipocalin-type Prostaglandin D Synthase Gene Expression through De-repression of Notch-HES Signaling and Enhancement of AP-2{beta} Function in Brain-derived TE671 Cells
J. Biol. Chem. 2005 280: 18452-18461. First Published on March 2, 2005; doi:10.1074/jbc.M411755200 [Abstract] [Full Text] [PDF]  

Yoshiharu Takayama, Petra May, Richard G. W. Anderson, and Joachim Herz
Low Density Lipoprotein Receptor-related Protein 1 (LRP1) Controls Endocytosis and c-CBL-mediated Ubiquitination of the Platelet-derived Growth Factor Receptor {beta} (PDGFR{beta})
J. Biol. Chem. 2005 280: 18504-18510. First Published on March 7, 2005; doi:10.1074/jbc.M410265200 [Abstract] [Full Text] [PDF]  

Motonobu Anai, Nobuhiro Shojima, Hideki Katagiri, Takehide Ogihara, Hideyuki Sakoda, Yukiko Onishi, Hiraku Ono, Midori Fujishiro, Yasushi Fukushima, Nanao Horike, Amelia Viana, Masatoshi Kikuchi, Noriko Noguchi, Shinichiro Takahashi, Kuniaki Takata, Yoshitomo Oka, Yasunobu Uchijima, Hiroki Kurihara, and Tomoichiro Asano
A Novel Protein Kinase B (PKB)/AKT-binding Protein Enhances PKB Kinase Activity and Regulates DNA Synthesis
J. Biol. Chem. 2005 280: 18525-18535. First Published on March 7, 2005; doi:10.1074/jbc.M500586200 [Abstract] [Full Text] [PDF]  

Cheng-Che Lee, Chiung-Chun Huang, Mei-Ying Wu, and Kuei-Sen Hsu
Insulin Stimulates Postsynaptic Density-95 Protein Translation via the Phosphoinositide 3-Kinase-Akt-Mammalian Target of Rapamycin Signaling Pathway
J. Biol. Chem. 2005 280: 18543-18550. First Published on March 8, 2005; doi:10.1074/jbc.M414112200 [Abstract] [Full Text] [PDF]  


Molecular Basis Of Cell and Developmental Biology:Back

Tim S. Fisher, Shelley Des Etages, Lisa Hayes, Kim Crimin, and Baiyong Li
Analysis of ARD1 Function in Hypoxia Response Using Retroviral RNA Interference
J. Biol. Chem. 2005 280: 17749-17757. First Published on March 8, 2005; doi:10.1074/jbc.M412055200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Yougen Zhan, Mathieu R. Tremblay, Nadia Melian, and Salvatore Carbonetto
Evidence That Dystroglycan Is Associated with Dynamin and Regulates Endocytosis
J. Biol. Chem. 2005 280: 18015-18024. First Published on February 22, 2005; doi:10.1074/jbc.M409682200 [Abstract] [Full Text] [PDF]  

Ehab H. Sarsour, Manjula Agarwal, Tej K. Pandita, Larry W. Oberley, and Prabhat C. Goswami
Manganese Superoxide Dismutase Protects the Proliferative Capacity of Confluent Normal Human Fibroblasts
J. Biol. Chem. 2005 280: 18033-18041. First Published on March 2, 2005; doi:10.1074/jbc.M501939200 [Abstract] [Full Text] [PDF]  

Yoon-Jin Lee, Dae-Hoon Lee, Chul-Koo Cho, Sangwoo Bae, Gil-Ja Jhon, Su-Jae Lee, Jae-Won Soh, and Yun-Sil Lee
HSP25 Inhibits Protein Kinase C{delta}-mediated Cell Death through Direct Interaction
J. Biol. Chem. 2005 280: 18108-18119. First Published on February 24, 2005; doi:10.1074/jbc.M501131200 [Abstract] [Full Text] [PDF]  

María J. Muñoz-Alonso, Juan C. Acosta, Carlos Richard, M. Dolores Delgado, John Sedivy, and Javier León
p21Cip1 and p27Kip1 Induce Distinct Cell Cycle Effects and Differentiation Programs in Myeloid Leukemia Cells
J. Biol. Chem. 2005 280: 18120-18129. First Published on March 3, 2005; doi:10.1074/jbc.M500758200 [Abstract] [Full Text] [PDF]  

Nguan Soon Tan, Liliane Michalik, Béatrice Desvergne, and Walter Wahli
Genetic- or Transforming Growth Factor-{beta}1-induced Changes in Epidermal Peroxisome Proliferator-activated Receptor {beta}/{delta} Expression Dictate Wound Repair Kinetics
J. Biol. Chem. 2005 280: 18163-18170. First Published on February 11, 2005; doi:10.1074/jbc.M412829200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Yu Wang, Karen S. L. Lam, Jian Yu Xu, Gang Lu, Lance Yi Xu, Garth J. S. Cooper, and Aimin Xu
Adiponectin Inhibits Cell Proliferation by Interacting with Several Growth Factors in an Oligomerization-dependent Manner
J. Biol. Chem. 2005 280: 18341-18347. First Published on February 25, 2005; doi:10.1074/jbc.M501149200 [Abstract] [Full Text] [PDF]  


Additions and Corrections:Back

Isabelle Chantret, Julia Dancourt, Alain Barbat, and Stuart E. H. Moore
Two proteins homologous to the N- and C-terminal domains of the bacterial glycosyltransferase Murg are required for the second step of dolichyl-linked oligosaccharide synthesis in Saccharomyces cerevisiae. Vol. 280 (2005) 9236-9242
J. Biol. Chem. 2005 280: 18551-18552. [Full Text] [PDF]  


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