JBC -- Table of Contents (May 27 2005, 280, (21))

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Classics:

Nicole Kresge, Robert D. Simoni, and Robert L. Hill: Fritz Lipmann and the Discovery of Coenzyme A
ACETYLATION OF SULFANILAMIDE BY LIVER HOMOGENATES AND EXTRACTS (Fritz Lipmann J. Biol. Chem. 160, 173-190)
J. Biol. Chem. 2005 280: e18. [Full Text]

Minireviews:

Christine McDonald, Naohiro Inohara, and Gabriel Nuñez: Peptidoglycan Signaling in Innate Immunity and Inflammatory Disease
J. Biol. Chem. 2005 280: 20177-20180. First Published on March 31, 2005; doi:10.1074/jbc.R500001200 [Full Text] [PDF]

Accelerated Publications:

Annabelle Varrot, Sabine Leydier, Gavin Pell, James M. Macdonald, Robert V. Stick, Bernard Henrissat, Harry J. Gilbert, and Gideon J. Davies: Mycobacterium tuberculosis Strains Possess Functional Cellulases
J. Biol. Chem. 2005 280: 20181-20184. First Published on April 11, 2005; doi:10.1074/jbc.C500142200 [Abstract] [Full Text] [PDF]

Leisl A. Brand and Erick Strauss: Characterization of a New Pantothenate Kinase Isoform from Helicobacter pylori
J. Biol. Chem. 2005 280: 20185-20188. First Published on March 28, 2005; doi:10.1074/jbc.C500044200 [Abstract] [Full Text] [PDF] [Supplemental Data]

DNA: Replication, Repair, and Recombination:

Daniel Coman and Irina M. Russu: Base Pair Opening in Three DNA-unwinding Elements
J. Biol. Chem. 2005 280: 20216-20221. First Published on March 21, 2005; doi:10.1074/jbc.M502773200 [Abstract] [Full Text] [PDF]

Anne E. Clatworthy, Maria A. Valencia-Burton, James E. Haber, and Marjorie A. Oettinger: The MRE11-RAD50-XRS2 Complex, in Addition to Other Non-homologous End-joining Factors, Is Required for V(D)J Joining in Yeast
J. Biol. Chem. 2005 280: 20247-20252. First Published on March 9, 2005; doi:10.1074/jbc.M500126200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Ming Lei, Arthur J. Zaug, Elaine R. Podell, and Thomas R. Cech: Switching Human Telomerase On and Off with hPOT1 Protein in Vitro
J. Biol. Chem. 2005 280: 20449-20456. First Published on March 24, 2005; doi:10.1074/jbc.M502212200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Tao-shih Hsieh and Christopher Capp: Nucleotide- and Stoichiometry-dependent DNA Supercoiling by Reverse Gyrase
J. Biol. Chem. 2005 280: 20467-20475. First Published on March 22, 2005; doi:10.1074/jbc.M502739200 [Abstract] [Full Text] [PDF]

Genes: Structure and Regulation:

Yutaka Furutani, Akira Kato, Azzania Fibriani, Taku Hirata, Ryoji Kawai, Ju-Hong Jeon, Yasuhisa Fujii, In-Gyu Kim, Soichi Kojima, and Shigehisa Hirose: Identification, Evolution, and Regulation of Expression of Guinea Pig Trappin with an Unusually Long Transglutaminase Substrate Domain
J. Biol. Chem. 2005 280: 20204-20215. First Published on March 18, 2005; doi:10.1074/jbc.M501678200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Weimin Miao, Lianggao Hu, P. James Scrivens, and Gerald Batist: Transcriptional Regulation of NF-E2 p45-related Factor (NRF2) Expression by the Aryl Hydrocarbon Receptor-Xenobiotic Response Element Signaling Pathway: DIRECT CROSS-TALK BETWEEN PHASE I AND II DRUG-METABOLIZING ENZYMES
J. Biol. Chem. 2005 280: 20340-20348. First Published on March 23, 2005; doi:10.1074/jbc.M412081200 [Abstract] [Full Text] [PDF]

Minori Dateki, Takuro Horii, Yoshitoshi Kasuya, Reiko Mochizuki, Yasumitsu Nagao, Junji Ishida, Fumihiro Sugiyama, Keiji Tanimoto, Ken-ichi Yagami, Hiroshi Imai, and Akiyoshi Fukamizu: Neurochondrin Negatively Regulates CaMKII Phosphorylation, and Nervous System-specific Gene Disruption Results in Epileptic Seizure
J. Biol. Chem. 2005 280: 20503-20508. First Published on March 24, 2005; doi:10.1074/jbc.M414033200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Leonid E. Lerner, Guang-Hua Peng, Yekaterina E. Gribanova, Shiming Chen, and Debora B. Farber: Sp4 Is Expressed in Retinal Neurons, Activates Transcription of Photoreceptor-specific Genes, and Synergizes with Crx
J. Biol. Chem. 2005 280: 20642-20650. First Published on March 21, 2005; doi:10.1074/jbc.M500957200 [Abstract] [Full Text] [PDF]

Wuchen Yang, Yongbo Lu, Ivo Kalajzic, Dayong Guo, Marie A. Harris, Jelica Gluhak-Heinrich, Shiva Kotha, Lynda F. Bonewald, Jian Q. Feng, David W. Rowe, Charles H. Turner, Alexander G. Robling, and Stephen E. Harris: Dentin Matrix Protein 1 Gene Cis-regulation: USE IN OSTEOCYTES TO CHARACTERIZE LOCAL RESPONSES TO MECHANICAL LOADING IN VITRO AND IN VIVO
J. Biol. Chem. 2005 280: 20680-20690. First Published on February 22, 2005; doi:10.1074/jbc.M500104200 [Abstract] [Full Text] [PDF]

Li Pan, Sean T. Glenn, Craig A. Jones, and Kenneth W. Gross: Activation of the Rat Renin Promoter by HOXD10·PBX1b·PREP1, Ets-1, and the Intracellular Domain of Notch
J. Biol. Chem. 2005 280: 20860-20866. First Published on March 25, 2005; doi:10.1074/jbc.M414618200 [Abstract] [Full Text] [PDF]

María-Eugenia Guazzaroni, Tino Krell, Antonia Felipe, Raquel Ruiz, Cuixiang Meng, Xiaodong Zhang, María-Trinidad Gallegos, and Juan L. Ramos: The Multidrug Efflux Regulator TtgV Recognizes a Wide Range of Structurally Different Effectors in Solution and Complexed with Target DNA: EVIDENCE FROM ISOTHERMAL TITRATION CALORIMETRY
J. Biol. Chem. 2005 280: 20887-20893. First Published on March 13, 2005; doi:10.1074/jbc.M500783200 [Abstract] [Full Text] [PDF]

RNA: Structure, Metabolism, and Catalysis:

Stéphane Hausmann, Sushuang Zheng, Carme Fabrega, Stewart W. Schneller, Christopher D. Lima, and Stewart Shuman: Encephalitozoon cuniculi mRNA Cap (Guanine N-7) Methyltransferase: METHYL ACCEPTOR SPECIFICITY, INHIBITION BY S-ADENOSYLMETHIONINE ANALOGS, AND STRUCTURE-GUIDED MUTATIONAL ANALYSIS
J. Biol. Chem. 2005 280: 20404-20412. First Published on March 9, 2005; doi:10.1074/jbc.M501073200 [Abstract] [Full Text] [PDF]

Alexander Best, Lusy Handoko, Elke Schlüter, and H. U. Göringer: In Vitro Synthesized Small Interfering RNAs Elicit RNA Interference in African Trypanosomes: AN IN VITRO AND IN VIVO ANALYSIS
J. Biol. Chem. 2005 280: 20573-20579. First Published on March 21, 2005; doi:10.1074/jbc.M414534200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Protein Synthesis, Post-Translation Modification, and Degradation:

Fu Shang, Gejing Deng, Qing Liu, Weimin Guo, Arthur L. Haas, Bernat Crosas, Daniel Finley, and Allen Taylor: Lys⁶-modified Ubiquitin Inhibits Ubiquitin-dependent Protein Degradation
J. Biol. Chem. 2005 280: 20365-20374. First Published on March 24, 2005; doi:10.1074/jbc.M414356200 [Abstract] [Full Text] [PDF]

Nikolai A. Timchenko, Gou-Li Wang, and Lubov T. Timchenko: RNA CUG-binding Protein 1 Increases Translation of 20-kDa Isoform of CCAAT/Enhancer-binding Protein ${beta}$ by Interacting with the ${alpha}$ and ${beta}$ Subunits of Eukaryotic Initiation Translation Factor 2
J. Biol. Chem. 2005 280: 20549-20557. First Published on March 23, 2005; doi:10.1074/jbc.M409563200 [Abstract] [Full Text] [PDF]

Liang Feng, Jing Yuan, Helen Toogood, Debra Tumbula-Hansen, and Dieter Söll: Aspartyl-tRNA Synthetase Requires a Conserved Proline in the Anticodon-binding Loop for tRNA^Asn Recognition in Vivo
J. Biol. Chem. 2005 280: 20638-20641. First Published on March 21, 2005; doi:10.1074/jbc.M500874200 [Abstract] [Full Text] [PDF]

Genomics, Proteomics, and Bioinformatics:

Yan Zhang, Pavel V. Baranov, John F. Atkins, and Vadim N. Gladyshev: Pyrrolysine and Selenocysteine Use Dissimilar Decoding Strategies
J. Biol. Chem. 2005 280: 20740-20751. First Published on March 22, 2005; doi:10.1074/jbc.M501458200 [Abstract] [Full Text] [PDF]

Qing Yuan Yin, Piet W. J. de Groot, Henk L. Dekker, Luitzen de Jong, Frans M. Klis, and Chris G. de Koster: Comprehensive Proteomic Analysis of Saccharomyces cerevisiae Cell Walls: IDENTIFICATION OF PROTEINS COVALENTLY ATTACHED VIA GLYCOSYLPHOSPHATIDYLINOSITOL REMNANTS OR MILD ALKALI-SENSITIVE LINKAGES
J. Biol. Chem. 2005 280: 20894-20901. First Published on March 21, 2005; doi:10.1074/jbc.M500334200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Protein Structure and Folding:

Maria Schumacher, Kazunori Mizuno, and Hans Peter Bächinger: The Crystal Structure of the Collagen-like Polypeptide (Glycyl-4(R)-hydroxyprolyl-4(R)-hydroxyprolyl)₉ at 1.55 Å Resolution Shows Up-puckering of the Proline Ring in the Xaa Position
J. Biol. Chem. 2005 280: 20397-20403. First Published on March 22, 2005; doi:10.1074/jbc.M501453200 [Abstract] [Full Text] [PDF]

Dharmendar Rathore, Rana Nagarkatti, Dewal Jani, Rana Chattopadhyay, Patricia de la Vega, Sanjai Kumar, and Thomas F. McCutchan: An Immunologically Cryptic Epitope of Plasmodium falciparum Circumsporozoite Protein Facilitates Liver Cell Recognition and Induces Protective Antibodies That Block Liver Cell Invasion
J. Biol. Chem. 2005 280: 20524-20529. First Published on March 21, 2005; doi:10.1074/jbc.M414254200 [Abstract] [Full Text] [PDF]

Sonja A. Dames, José M. Mulet, Klara Rathgeb-Szabo, Michael N. Hall, and Stephan Grzesiek: The Solution Structure of the FATC Domain of the Protein Kinase Target of Rapamycin Suggests a Role for Redox-dependent Structural and Cellular Stability
J. Biol. Chem. 2005 280: 20558-20564. First Published on March 16, 2005; doi:10.1074/jbc.M501116200 [Abstract] [Full Text] [PDF]

Juan Luis Asensio, Armando Albert, Daniel Muñoz-Espín, Carlos Gonzalez, Juan Hermoso, Laurentino Villar, Jesús Jiménez-Barbero, Margarita Salas, and Wilfried J. J. Meijer: Structure of the Functional Domain of ${varphi}$ 29 Replication Organizer: INSIGHTS INTO OLIGOMERIZATION AND DNA BINDING
J. Biol. Chem. 2005 280: 20730-20739. First Published on March 16, 2005; doi:10.1074/jbc.M501687200 [Abstract] [Full Text] [PDF] [Supplemental Data]

David C. Williams, Jr., Mengli Cai, Jeong-Yong Suh, Alan Peterkofsky, and G. Marius Clore: Solution NMR Structure of the 48-kDa IIA^Mannose-HPr Complex of the Escherichia coli Mannose Phosphotransferase System
J. Biol. Chem. 2005 280: 20775-20784. First Published on March 23, 2005; doi:10.1074/jbc.M501986200 [Abstract] [Full Text] [PDF]

Esther Kellenberger, Cyril Dominguez, Sébastien Fribourg, Emeric Wasielewski, Dino Moras, Arnaud Poterszman, Rolf Boelens, and Bruno Kieffer: Solution Structure of the C-terminal Domain of TFIIH P44 Subunit Reveals a Novel Type of C4C4 Ring Domain Involved in Protein-Protein Interactions
J. Biol. Chem. 2005 280: 20785-20792. First Published on March 24, 2005; doi:10.1074/jbc.M412999200 [Abstract] [Full Text] [PDF]

Jesús Mingorance, Michael Tadros, Miguel Vicente, José Manuel González, Germán Rivas, and Marisela Vélez: Visualization of Single Escherichia coli FtsZ Filament Dynamics with Atomic Force Microscopy
J. Biol. Chem. 2005 280: 20909-20914. First Published on March 26, 2005; doi:10.1074/jbc.M503059200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Enzyme Catalysis and Regulation:

Weiwei Shi, John Mersfelder, and Russ Hille: The Interaction of Trimethylamine Dehydrogenase and Electron-transferring Flavoprotein
J. Biol. Chem. 2005 280: 20239-20246. First Published on March 9, 2005; doi:10.1074/jbc.M500582200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Atsushi Kurata, Tatsuo Kurihara, Harumi Kamachi, and Nobuyoshi Esaki: 2-Haloacrylate Reductase, a Novel Enzyme of the Medium Chain Dehydrogenase/Reductase Superfamily That Catalyzes the Reduction of a Carbon-Carbon Double Bond of Unsaturated Organohalogen Compounds
J. Biol. Chem. 2005 280: 20286-20291. First Published on March 21, 2005; doi:10.1074/jbc.M414605200 [Abstract] [Full Text] [PDF]

Tatyana Spolitak, John H. Dawson, and David P. Ballou: Reaction of Ferric Cytochrome P450cam with Peracids: KINETIC CHARACTERIZATION OF INTERMEDIATES ON THE REACTION PATHWAY
J. Biol. Chem. 2005 280: 20300-20309. First Published on March 21, 2005; doi:10.1074/jbc.M501761200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Josephine C. Ferreon, Allan Chris M. Ferreon, Kui Li, and Stanley M. Lemon: Molecular Determinants of TRIF Proteolysis Mediated by the Hepatitis C Virus NS3/4A Protease
J. Biol. Chem. 2005 280: 20483-20492. First Published on March 14, 2005; doi:10.1074/jbc.M500422200 [Abstract] [Full Text] [PDF]

Songyang Ren, Lisa Nguyen, Shaoxing Wu, Carlos Encinas, John S. Adams, and Martin Hewison: Alternative Splicing of Vitamin D-24-Hydroxylase: A NOVEL MECHANISM FOR THE REGULATION OF EXTRARENAL 1,25-DIHYDROXYVITAMIN D SYNTHESIS
J. Biol. Chem. 2005 280: 20604-20611. First Published on March 23, 2005; doi:10.1074/jbc.M414522200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Marcel Deponte, Sabine Urig, L. David Arscott, Karin Fritz-Wolf, Régis Réau, Christel Herold-Mende, Sasa Koncarevic, Markus Meyer, Elisabeth Davioud-Charvet, David P. Ballou, Charles H. Williams, Jr., and Katja Becker: Mechanistic Studies on a Novel, Highly Potent Gold-Phosphole Inhibitor of Human Glutathione Reductase
J. Biol. Chem. 2005 280: 20628-20637. First Published on March 24, 2005; doi:10.1074/jbc.M412519200 [Abstract] [Full Text] [PDF]

Prachee Prakash, Niteen Pathak, and Seyed E. Hasnain: pheA (Rv3838c) of Mycobacterium tuberculosis Encodes an Allosterically Regulated Monofunctional Prephenate Dehydratase That Requires Both Catalytic and Regulatory Domains for Optimum Activity
J. Biol. Chem. 2005 280: 20666-20671. First Published on March 7, 2005; doi:10.1074/jbc.M502107200 [Abstract] [Full Text] [PDF]

Ken Okada and Toshiharu Hase: Cyanobacterial Non-mevalonate Pathway: (E)-4-HYDROXY-3-METHYLBUT-2-ENYL DIPHOSPHATE SYNTHASE INTERACTS WITH FERREDOXIN IN THERMOSYNECHOCOCCUS ELONGATUS BP-1
J. Biol. Chem. 2005 280: 20672-20679. First Published on March 25, 2005; doi:10.1074/jbc.M500865200 [Abstract] [Full Text] [PDF]

Vandana Mishra, Sameeta Bilgrami, Radhey Shyam Sharma, Punit Kaur, Savita Yadav, Ruth Krauspenhaar, Christian Betzel, Wolfgang Voelter, Cherukuri R. Babu, and Tej P. Singh: Crystal Structure of Himalayan Mistletoe Ribosome-inactivating Protein Reveals the Presence of a Natural Inhibitor and a New Functionally Active Sugar-binding Site
J. Biol. Chem. 2005 280: 20712-20721. First Published on March 17, 2005; doi:10.1074/jbc.M500735200 [Abstract] [Full Text] [PDF]

Rey-Ting Guo, Tzu-Ping Ko, Annie P.-C. Chen, Chih-Jung Kuo, Andrew H.-J. Wang, and Po-Huang Liang: Crystal Structures of Undecaprenyl Pyrophosphate Synthase in Complex with Magnesium, Isopentenyl Pyrophosphate, and Farnesyl Thiopyrophosphate: ROLES OF THE METAL ION AND CONSERVED RESIDUES IN CATALYSIS
J. Biol. Chem. 2005 280: 20762-20774. First Published on March 23, 2005; doi:10.1074/jbc.M502121200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Yoshihiro Yamaguchi, Takahiro Kuroki, Hisami Yasuzawa, Toshihiro Higashi, Wanchun Jin, Akiko Kawanami, Yuriko Yamagata, Yoshichika Arakawa, Masafumi Goto, and Hiromasa Kurosaki: Probing the Role of Asp-120(81) of Metallo- ${beta}$ -lactamase (IMP-1) by Site-directed Mutagenesis, Kinetic Studies, and X-ray Crystallography
J. Biol. Chem. 2005 280: 20824-20832. First Published on March 23, 2005; doi:10.1074/jbc.M414314200 [Abstract] [Full Text] [PDF]

Ravinder Kaur Obhi and Carole Creuzenet: Biochemical Characterization of the Campylobacter jejuni Cj1294, a Novel UDP-4-keto-6-deoxy-GlcNAc Aminotransferase That Generates UDP-4-amino-4,6-dideoxy-GalNAc
J. Biol. Chem. 2005 280: 20902-20908. First Published on March 24, 2005; doi:10.1074/jbc.M413832200 [Abstract] [Full Text] [PDF]

Metabolism and Bioenergetics:

Beth Marbois, Peter Gin, Kym F. Faull, Wayne W. Poon, Peter T. Lee, Jeff Strahan, Jennifer N. Shepherd, and Catherine F. Clarke: Coq3 and Coq4 Define a Polypeptide Complex in Yeast Mitochondria for the Biosynthesis of Coenzyme Q
J. Biol. Chem. 2005 280: 20231-20238. First Published on March 25, 2005; doi:10.1074/jbc.M501315200 [Abstract] [Full Text] [PDF]

Geert A. Martens, Ying Cai, Simon Hinke, Geert Stangé, Mark Van de Casteele, and Daniel Pipeleers: Glucose Suppresses Superoxide Generation in Metabolically Responsive Pancreatic ${beta}$ Cells
J. Biol. Chem. 2005 280: 20389-20396. First Published on March 17, 2005; doi:10.1074/jbc.M411869200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Bianca Naumann, Einar J. Stauber, Andreas Busch, Frederik Sommer, and Michael Hippler: N-terminal Processing of Lhca3 Is a Key Step in Remodeling of the Photosystem I-Light-harvesting Complex Under Iron Deficiency in Chlamydomonas reinhardtii
J. Biol. Chem. 2005 280: 20431-20441. First Published on March 17, 2005; doi:10.1074/jbc.M414486200 [Abstract] [Full Text] [PDF]

Louise D. McCullough, Zhiyuan Zeng, Hong Li, Leslie E. Landree, Jill McFadden, and Gabriele V. Ronnett: Pharmacological Inhibition of AMP-activated Protein Kinase Provides Neuroprotection in Stroke
J. Biol. Chem. 2005 280: 20493-20502. First Published on March 16, 2005; doi:10.1074/jbc.M409985200 [Abstract] [Full Text] [PDF]

Tomas Morosinotto, Milena Mozzo, Roberto Bassi, and Roberta Croce: Pigment-Pigment Interactions in Lhca4 Antenna Complex of Higher Plants Photosystem I
J. Biol. Chem. 2005 280: 20612-20619. First Published on March 23, 2005; doi:10.1074/jbc.M500705200 [Abstract] [Full Text] [PDF]

Anke Bentmann, Marc Schmidt, Stefan Reuss, Uwe Wolfrum, Thomas Hankeln, and Thorsten Burmester: Divergent Distribution in Vascular and Avascular Mammalian Retinae Links Neuroglobin to Cellular Respiration
J. Biol. Chem. 2005 280: 20660-20665. First Published on March 25, 2005; doi:10.1074/jbc.M501338200 [Abstract] [Full Text] [PDF]

Glycobiology and Extracellular Matrices:

Naoto Yonezawa, Katsuyasu Kudo, Hirotomo Terauchi, Saeko Kanai, Naoto Yoda, Masaru Tanokura, Kosuke Ito, Kin-ichiro Miura, Toshiyuki Katsumata, and Minoru Nakano: Recombinant Porcine Zona Pellucida Glycoproteins Expressed in Sf9 Cells Bind to Bovine Sperm but Not to Porcine Sperm
J. Biol. Chem. 2005 280: 20189-20196. First Published on March 23, 2005; doi:10.1074/jbc.M414242200 [Abstract] [Full Text] [PDF]

Hanspeter Kählig, Daniel Kolarich, Sonja Zayni, Andrea Scheberl, Paul Kosma, Christina Schäffer, and Paul Messner: N-Acetylmuramic Acid as Capping Element of ${alpha}$ -D-Fucose-containing S-layer Glycoprotein Glycans from Geobacillus tepidamans GS5–97^T
J. Biol. Chem. 2005 280: 20292-20299. First Published on March 21, 2005; doi:10.1074/jbc.M501724200 [Abstract] [Full Text] [PDF]

Leslie C. Nehring, Alison Miyamoto, Patrick W. Hein, Gerry Weinmaster, and J. Michael Shipley: The Extracellular Matrix Protein MAGP-2 Interacts with Jagged1 and Induces Its Shedding from the Cell Surface
J. Biol. Chem. 2005 280: 20349-20355. First Published on March 23, 2005; doi:10.1074/jbc.M500273200 [Abstract] [Full Text] [PDF]

Flonia Levy-Adam, Ghada Abboud-Jarrous, Marco Guerrini, Daniela Beccati, Israel Vlodavsky, and Neta Ilan: Identification and Characterization of Heparin/Heparan Sulfate Binding Domains of the Endoglycosidase Heparanase
J. Biol. Chem. 2005 280: 20457-20466. First Published on March 10, 2005; doi:10.1074/jbc.M414546200 [Abstract] [Full Text] [PDF]

Jacob van den Born, Katriina Salmivirta, Tiina Henttinen, Nina Östman, Takeshi Ishimaru, Shuichi Miyaura, Keiichi Yoshida, and Markku Salmivirta: Novel Heparan Sulfate Structures Revealed by Monoclonal Antibodies
J. Biol. Chem. 2005 280: 20516-20523. First Published on March 18, 2005; doi:10.1074/jbc.M502065200 [Abstract] [Full Text] [PDF]

Santosh K. Patnaik and Pamela Stanley: Mouse Large Can Modify Complex N- and Mucin O-Glycans on ${alpha}$ -Dystroglycan to Induce Laminin Binding
J. Biol. Chem. 2005 280: 20851-20859. First Published on March 23, 2005; doi:10.1074/jbc.M500069200 [Abstract] [Full Text] [PDF]

Heping Xu, Hitoshi Kurihara, Tomomi Ito, Hiroshi Kikuchi, Keiichi Yoshida, Hiroko Yamanokuchi, and Akira Asari: The Keratan Sulfate Disaccharide Gal(6S03) ${beta}$ 1,4-GlcNAc(6S03) Modulates Interleukin 12 Production by Macrophages in Murine Thy-1 Type Autoimmune Disease
J. Biol. Chem. 2005 280: 20879-20886. First Published on March 4, 2005; doi:10.1074/jbc.M411954200 [Abstract] [Full Text] [PDF]

Membrane Transport, Structure, Function, and Biogenesis:

Françoise Hoegy, Hervé Celia, Gaëtan L. Mislin, Michel Vincent, Jacques Gallay, and Isabelle J. Schalk: Binding of Iron-free Siderophore, a Common Feature of Siderophore Outer Membrane Transporters of Escherichia coli and Pseudomonas aeruginosa
J. Biol. Chem. 2005 280: 20222-20230. First Published on March 22, 2005; doi:10.1074/jbc.M500776200 [Abstract] [Full Text] [PDF]

Hyun Kim, Gunnar von Heijne, and IngMarie Nilsson: Membrane Topology of the STT3 Subunit of the Oligosaccharyl Transferase Complex
J. Biol. Chem. 2005 280: 20261-20267. First Published on March 21, 2005; doi:10.1074/jbc.M412213200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Yonggang Zhou and Baruch I. Kanner: Transporter-associated Currents in the ${gamma}$ -Aminobutyric Acid Transporter GAT-1 Are Conditionally Impaired by Mutations of a Conserved Glycine Residue
J. Biol. Chem. 2005 280: 20316-20324. First Published on March 22, 2005; doi:10.1074/jbc.M412937200 [Abstract] [Full Text] [PDF]

Kenneth L. Madsen, Thijs Beuming, Masha Y. Niv, Chiun-wen Chang, Kumlesh K. Dev, Harel Weinstein, and Ulrik Gether: Molecular Determinants for the Complex Binding Specificity of the PDZ Domain in PICK1
J. Biol. Chem. 2005 280: 20539-20548. First Published on March 17, 2005; doi:10.1074/jbc.M500577200 [Abstract] [Full Text] [PDF]

Dan Liu, Zheng Zhang, and Emily R. Liman: Extracellular Acid Block and Acid-enhanced Inactivation of the Ca²⁺-activated Cation Channel TRPM5 Involve Residues in the S3-S4 and S5-S6 Extracellular Domains
J. Biol. Chem. 2005 280: 20691-20699. First Published on February 24, 2005; doi:10.1074/jbc.M414072200 [Abstract] [Full Text] [PDF]

Srikumar M. Raja, Sunil S. Metkar, Stefan Höning, Baikun Wang, William A. Russin, Nina H. Pipalia, Cheikh Menaa, Mattias Belting, Xuefang Cao, Ralf Dressel, and Christopher J. Froelich: A Novel Mechanism for Protein Delivery: GRANZYME B UNDERGOES ELECTROSTATIC EXCHANGE FROM SERGLYCIN TO TARGET CELLS
J. Biol. Chem. 2005 280: 20752-20761. First Published on March 23, 2005; doi:10.1074/jbc.M501181200 [Abstract] [Full Text] [PDF]

Mechanisms Of Signal Transduction:

Jean-Louis Banères, Danielle Mesnier, Aimée Martin, Lara Joubert, Aline Dumuis, and Joel Bockaert: Molecular Characterization of a Purified 5-HT4 Receptor: A STRUCTURAL BASIS FOR DRUG EFFICACY
J. Biol. Chem. 2005 280: 20253-20260. First Published on March 17, 2005; doi:10.1074/jbc.M412009200 [Abstract] [Full Text] [PDF]

Suniti Misra, Shibnath Ghatak, and Bryan P. Toole: Regulation of MDR1 Expression and Drug Resistance by a Positive Feedback Loop Involving Hyaluronan, Phosphoinositide 3-Kinase, and ErbB2
J. Biol. Chem. 2005 280: 20310-20315. First Published on March 22, 2005; doi:10.1074/jbc.M500737200 [Abstract] [Full Text] [PDF] [Summary]

Wang Wang, Lingyun Jia, Tengke Wang, Wenting Sun, Sheng Wu, and Xian Wang: Endogenous Calcitonin Gene-related Peptide Protects Human Alveolar Epithelial Cells through Protein Kinase C ${epsilon}$ and Heat Shock Protein
J. Biol. Chem. 2005 280: 20325-20330. First Published on March 22, 2005; doi:10.1074/jbc.M413864200 [Abstract] [Full Text] [PDF] [Supplemental Data]

C. Nathaniel Roybal, Lucy A. Hunsaker, Olena Barbash, David L. Vander Jagt, and Steve F. Abcouwer: The Oxidative Stressor Arsenite Activates Vascular Endothelial Growth Factor mRNA Transcription by an ATF4-dependent Mechanism
J. Biol. Chem. 2005 280: 20331-20339. First Published on March 23, 2005; doi:10.1074/jbc.M411275200 [Abstract] [Full Text] [PDF]

Sivanandhan Dhanalakshmi, Chapla Agarwal, Rana P. Singh, and Rajesh Agarwal: Silibinin Up-regulates DNA-Protein Kinase-dependent p53 Activation to Enhance UVB-induced Apoptosis in Mouse Epithelial JB6 Cells
J. Biol. Chem. 2005 280: 20375-20383. First Published on March 25, 2005; doi:10.1074/jbc.M414640200 [Abstract] [Full Text] [PDF]

Anne Kasus-Jacobi, Jiafu Ou, David G. Birch, Kirsten G. Locke, John M. Shelton, James A. Richardson, Andrew J. Murphy, David M. Valenzuela, George D. Yancopoulos, and Albert O. Edwards: Functional Characterization of Mouse RDH11 as a Retinol Dehydrogenase Involved in Dark Adaptation in Vivo
J. Biol. Chem. 2005 280: 20413-20420. First Published on March 24, 2005; doi:10.1074/jbc.M413789200 [Abstract] [Full Text] [PDF]

Marilena Lanzino, Francesca De Amicis, Michael J. McPhaul, Stefania Marsico, Maria Luisa Panno, and Sebastiano Andò: Endogenous Coactivator ARA70 Interacts with Estrogen Receptor ${alpha}$ (ER ${alpha}$ ) and Modulates the Functional ER ${alpha}$ /Androgen Receptor Interplay in MCF-7 Cells
J. Biol. Chem. 2005 280: 20421-20430. First Published on March 15, 2005; doi:10.1074/jbc.M413576200 [Abstract] [Full Text] [PDF]

Jeonghee Cho, Michael Melnick, Georgios P. Solidakis, and Philip N. Tsichlis: Tpl2 (Tumor Progression Locus 2) Phosphorylation at Thr²⁹⁰ Is Induced by Lipopolysaccharide via an I ${kappa}$ -B Kinase- ${beta}$ -dependent Pathway and Is Required for Tpl2 Activation by External Signals
J. Biol. Chem. 2005 280: 20442-20448. First Published on March 18, 2005; doi:10.1074/jbc.M413554200 [Abstract] [Full Text] [PDF]

Andrew J. Thompson, Kerry L. Price, David C. Reeves, S. Ling Chan, P.-L. Chau, and Sarah C. R. Lummis: Locating an Antagonist in the 5-HT₃ Receptor Binding Site Using Modeling and Radioligand Binding
J. Biol. Chem. 2005 280: 20476-20482. First Published on March 21, 2005; doi:10.1074/jbc.M413610200 [Abstract] [Full Text] [PDF]

Felice A. Chow, Kristin A. Anderson, Pamela K. Noeldner, and Anthony R. Means: The Autonomous Activity of Calcium/Calmodulin-dependent Protein Kinase IV Is Required for Its Role in Transcription
J. Biol. Chem. 2005 280: 20530-20538. First Published on March 15, 2005; doi:10.1074/jbc.M500067200 [Abstract] [Full Text] [PDF] [Supplemental data]

Immo A. Hansen, Geoffrey M. Attardo, Saurabh G. Roy, and Alexander S. Raikhel: Target of Rapamycin-dependent Activation of S6 Kinase Is a Central Step in the Transduction of Nutritional Signals during Egg Development in a Mosquito
J. Biol. Chem. 2005 280: 20565-20572. First Published on March 23, 2005; doi:10.1074/jbc.M500712200 [Abstract] [Full Text] [PDF]

David Frescas, Luca Valenti, and Domenico Accili: Nuclear Trapping of the Forkhead Transcription Factor FoxO1 via Sirt-dependent Deacetylation Promotes Expression of Glucogenetic Genes
J. Biol. Chem. 2005 280: 20589-20595. First Published on March 22, 2005; doi:10.1074/jbc.M412357200 [Abstract] [Full Text] [PDF]

Holger Kneuper, Ingo G. Janausch, Vinesh Vijayan, Markus Zweckstetter, Verena Bock, Christian Griesinger, and Gottfried Unden: The Nature of the Stimulus and of the Fumarate Binding Site of the Fumarate Sensor DcuS of Escherichia coli
J. Biol. Chem. 2005 280: 20596-20603. First Published on March 21, 2005; doi:10.1074/jbc.M502015200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Uzma A. Hasan, Giorgio Trinchieri, and Jaromir Vlach: Toll-like Receptor Signaling Stimulates Cell Cycle Entry and Progression in Fibroblasts
J. Biol. Chem. 2005 280: 20620-20627. First Published on March 23, 2005; doi:10.1074/jbc.M500877200 [Abstract] [Full Text] [PDF]

Ashis K. Chowdhury, Tonya Watkins, Narasimham L. Parinandi, Bahman Saatian, Michael E. Kleinberg, Peter V. Usatyuk, and Viswanathan Natarajan: Src-mediated Tyrosine Phosphorylation of p47^phox in Hyperoxia-induced Activation of NADPH Oxidase and Generation of Reactive Oxygen Species in Lung Endothelial Cells
J. Biol. Chem. 2005 280: 20700-20711. First Published on March 17, 2005; doi:10.1074/jbc.M411722200 [Abstract] [Full Text] [PDF]

Jong-Ok Pyo, Mi-Hee Jang, Yun-Kyung Kwon, Ho-June Lee, Joon-IL Jun, Ha-Na Woo, Dong-Hyung Cho, BoYoun Choi, Heuiran Lee, Joo-Hang Kim, Noboru Mizushima, Yoshinori Oshumi, and Yong-Keun Jung: Essential Roles of Atg5 and FADD in Autophagic Cell Death: DISSECTION OF AUTOPHAGIC CELL DEATH INTO VACUOLE FORMATION AND CELL DEATH
J. Biol. Chem. 2005 280: 20722-20729. First Published on March 18, 2005; doi:10.1074/jbc.M413934200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Masayuki Matsushita, J. Ashot Kozak, Yoshio Shimizu, Derek T. McLachlin, Hiroto Yamaguchi, Fan-Yan Wei, Kazuhito Tomizawa, Hideki Matsui, Brian T. Chait, Michael D. Cahalan, and Angus C. Nairn: Channel Function Is Dissociated from the Intrinsic Kinase Activity and Autophosphorylation of TRPM7/ChaK1
J. Biol. Chem. 2005 280: 20793-20803. First Published on March 21, 2005; doi:10.1074/jbc.M413671200 [Abstract] [Full Text] [PDF]

Hamid Kashkar, Katja Wiegmann, Benjamin Yazdanpanah, Dirk Haubert, and Martin Krönke: Acid Sphingomyelinase Is Indispensable for UV Light-induced Bax Conformational Change at the Mitochondrial Membrane
J. Biol. Chem. 2005 280: 20804-20813. First Published on March 1, 2005; doi:10.1074/jbc.M410869200 [Abstract] [Full Text] [PDF]

Carsten Skurk, Yasuhiro Izumiya, Henrike Maatz, Peter Razeghi, Ichiro Shiojima, Marco Sandri, Kaori Sato, Ling Zeng, Stephan Schiekofer, David Pimentel, Stewart Lecker, Heinrich Taegtmeyer, Alfred L. Goldberg, and Kenneth Walsh: The FOXO3a Transcription Factor Regulates Cardiac Myocyte Size Downstream of AKT Signaling
J. Biol. Chem. 2005 280: 20814-20823. First Published on March 21, 2005; doi:10.1074/jbc.M500528200 [Abstract] [Full Text] [PDF]

Alexandre Semov, Maria J. Moreno, Anatoli Onichtchenko, Abedelnasser Abulrob, Marguerite Ball, Irena Ekiel, Grzegorz Pietrzynski, Danica Stanimirovic, and Valery Alakhov: Metastasis-associated Protein S100A4 Induces Angiogenesis through Interaction with Annexin II and Accelerated Plasmin Formation
J. Biol. Chem. 2005 280: 20833-20841. First Published on March 23, 2005; doi:10.1074/jbc.M412653200 [Abstract] [Full Text] [PDF]

Hong Xin, Xialian Xu, Linyu Li, Hongxiu Ning, Yu Rong, Yu Shang, Yinyin Wang, Xin-Yuan Fu, and Zhijie Chang: CHIP Controls the Sensitivity of Transforming Growth Factor- ${beta}$ Signaling by Modulating the Basal Level of Smad3 through Ubiquitin-mediated Degradation
J. Biol. Chem. 2005 280: 20842-20850. First Published on March 21, 2005; doi:10.1074/jbc.M412275200 [Abstract] [Full Text] [PDF]

Inmaculada Ortega-Pérez, Eva Cano, Felipe Were, Margarita Villar, Jesús Vázquez, and Juan Miguel Redondo: c-Jun N-terminal Kinase (JNK) Positively Regulates NFATc2 Transactivation through Phosphorylation within the N-terminal Regulatory Domain
J. Biol. Chem. 2005 280: 20867-20878. First Published on March 2, 2005; doi:10.1074/jbc.M501898200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Molecular Basis Of Cell and Developmental Biology:

Darren M. Hutt, Jay M. Baltz, and Johnny K. Ngsee: Synaptotagmin VI and VIII and Syntaxin 2 Are Essential for the Mouse Sperm Acrosome Reaction
J. Biol. Chem. 2005 280: 20197-20203. First Published on March 17, 2005; doi:10.1074/jbc.M412920200 [Abstract] [Full Text] [PDF]

Phyllis A. Essex-Fraser, Shelby L. Steele, Nicholas J. Bernier, Brent W. Murray, E. Don Stevens, and Patricia A. Wright: Expression of Four Glutamine Synthetase Genes in the Early Stages of Development of Rainbow Trout (Oncorhynchus mykiss) in Relationship to Nitrogen Excretion
J. Biol. Chem. 2005 280: 20268-20273. First Published on March 21, 2005; doi:10.1074/jbc.M412338200 [Abstract] [Full Text] [PDF]

Mario Galindo, Jitesh Pratap, Daniel W. Young, Hayk Hovhannisyan, Hee-Jeong Im, Je-Yong Choi, Jane B. Lian, Janet L. Stein, Gary S. Stein, and Andre J. van Wijnen: The Bone-specific Expression of Runx2 Oscillates during the Cell Cycle to Support a G₁-related Antiproliferative Function in Osteoblasts
J. Biol. Chem. 2005 280: 20274-20285. First Published on March 21, 2005; doi:10.1074/jbc.M413665200 [Abstract] [Full Text] [PDF]

Xiaoyu Zhang, Allison Zajac, Jian Zhang, Puyue Wang, Ming Li, John Murray, Daniel TerBush, and Wei Guo: The Critical Role of Exo84p in the Organization and Polarized Localization of the Exocyst Complex
J. Biol. Chem. 2005 280: 20356-20364. First Published on March 23, 2005; doi:10.1074/jbc.M500511200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Satoru Yamagishi, Masashi Fujitani, Katsuhiko Hata, Keiko Kitajo, Fumiaki Mimura, Hideki Abe, and Toshihide Yamashita: Wallerian Degeneration Involves Rho/Rho-kinase Signaling
J. Biol. Chem. 2005 280: 20384-20388. First Published on March 29, 2005; doi:10.1074/jbc.M501945200 [Abstract] [Full Text] [PDF] [Supplemental Data]

David Davidson, Antoine Blanc, Dominic Filion, Huifen Wang, Paul Plut, Gerald Pfeffer, Michael D. Buschmann, and Janet E. Henderson: Fibroblast Growth Factor (FGF) 18 Signals through FGF Receptor 3 to Promote Chondrogenesis
J. Biol. Chem. 2005 280: 20509-20515. First Published on March 21, 2005; doi:10.1074/jbc.M410148200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Chuan Shen, Daniel Nettleton, Min Jiang, Stuart K. Kim, and Jo Anne Powell-Coffman: Roles of the HIF-1 Hypoxia-inducible Factor during Hypoxia Response in Caenorhabditis elegans
J. Biol. Chem. 2005 280: 20580-20588. First Published on March 21, 2005; doi:10.1074/jbc.M501894200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Hai Jiang, Shouqing Luo, and Honglin Li: Cdk5 Activator-binding Protein C53 Regulates Apoptosis Induced by Genotoxic Stress via Modulating the G₂/M DNA Damage Checkpoint
J. Biol. Chem. 2005 280: 20651-20659. First Published on March 24, 2005; doi:10.1074/jbc.M413431200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Additions and Corrections:

Chii-Shen Yang, Oleg Sineshchekov, Elena N. Spudich, and John L. Spudich: The cytoplasmic membrane-proximal domain of the HtrII transducer interacts with the E-F loop of photoactivated Natronomonas pharaonis sensory rhodopsin II. Vol. 279 (2004) 42970–42976
J. Biol. Chem. 2005 280: 20915. [Full Text] [PDF]

Benjamin Barré, Arnaud Vigneron, and Olivier Coqueret: The STAT3 transcription factor is a target for the Myc and retinoblastoma proteins on the Cdc25A promoter. Vol. 280 (2005) 15673–15681
J. Biol. Chem. 2005 280: 20916. [Full Text] [PDF]

Marcos S. Toledo, Erika Suzuki, Kazuko Handa, and Senitiroh Hakomori: Effect of ganglioside and tetraspanins in microdomains on interaction of integrins with fibroblast growth factor receptor. Vol. 280 (2005) 16227–16234
J. Biol. Chem. 2005 280: 20916-a. [Full Text] [PDF]