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Table of Contents: Nov 11 2005; 280 (45)   [Index by Author]  [Papers Of The Week]
[Cover Figure and Caption] [Table of Contents (PDF)]
       Papers Of The Week
       Classics
       Minireviews
       DNA: Replication, Repair, and Recombination
       Genes: Structure and Regulation
       RNA: Structure, Metabolism, and Catalysis
       Protein Synthesis, Post-Translation Modification, and Degradation
       Protein Structure and Folding
       Enzyme Catalysis and Regulation
       Metabolism and Bioenergetics
       Glycobiology and Extracellular Matrices
       Lipids and Lipoproteins
       Membrane Transport, Structure, Function, and Biogenesis
       Mechanisms Of Signal Transduction
       Molecular Basis Of Cell and Developmental Biology
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Papers Of The Week:

There Is More than One Way to Stay Young
J. Biol. Chem. 2005 280: e99950. [Full Text] [PDF]  


Classics:

Nicole Kresge, Robert D. Simoni, and Robert L. Hill
Amino Acyl Ribonucleic Acid Formation and Recombinant DNA Technology: the Work of Paul Berg
The Enzymic Synthesis of Amino Acyl Derivatives of Ribonucleic Acid. I. THE MECHANISM OF LEUCYL-, VALYL-, ISOLEUCYL-, AND METHIONYL RIBONUCLEIC ACID FORMATION (Paul Berg, Fred H. Bergmann, E. J. Ofengand, and M. Dieckmann J. Biol. Chem. 236, 1726-1734)
The Enzymic Synthesis of Amino Acyl Derivatives of Ribonucleic Acid. II. THE PREPARATION OF LEUCYL-, VALYL-, ISOLEUCYL-, AND METHIONYL RIBONUCLEIC ACID SYNTHETASES FROM ESCHERICHIA COLI (Fred H. Bergmann, Paul Berg, and M. Dieckmann J. Biol. Chem. 236, 1735-1740)
The Enzymic Synthesis of Amino Acyl Derivatives of Ribonucleic Acid. III. ISOLATION OF AMINO ACID-ACCEPTOR RIBONUCLEIC ACIDS FROM ESCHERICHIA COLI (E. J. Ofengand, M. Dieckmann, and Paul Berg J. Biol. Chem. 236, 1741-1747)
J. Biol. Chem. 2005 280: e42. [Full Text]  


Minireviews:

Nicole LaRonde-LeBlanc and Alexander Wlodawer
A Family Portrait of the RIO Kinases
J. Biol. Chem. 2005 280: 37297-37300. First Published on September 22, 2005; doi:10.1074/jbc.R500013200 [Abstract] [Full Text] [PDF]  


DNA: Replication, Repair, and Recombination:

Marek Napierala, Albino Bacolla, and Robert D. Wells
Increased Negative Superhelical Density in Vivo Enhances the Genetic Instability of Triplet Repeat Sequences
J. Biol. Chem. 2005 280: 37366-37376. First Published on September 13, 2005; doi:10.1074/jbc.M508065200 [Abstract] [Full Text] [PDF]  

Jia Li and David F. Stern
DNA Damage Regulates Chk2 Association with Chromatin
J. Biol. Chem. 2005 280: 37948-37956. First Published on September 8, 2005; doi:10.1074/jbc.M509299200 [Abstract] [Full Text] [PDF]  


Genes: Structure and Regulation:

William F. Holmes, Corey D. Braastad, Partha Mitra, Cornelia Hampe, Detlef Doenecke, Werner Albig, Janet L. Stein, Andre J. van Wijnen, and Gary S. Stein
Coordinate Control and Selective Expression of the Full Complement of Replication-dependent Histone H4 Genes in Normal and Cancer Cells
J. Biol. Chem. 2005 280: 37400-37407. First Published on August 29, 2005; doi:10.1074/jbc.M506995200 [Abstract] [Full Text] [PDF]  

Petra Sander, Henning Hamann, Cord Drögemüller, Kseniya Kashkevich, Katrin Schiebel, and Tosso Leeb
Bovine Prion Protein Gene (PRNP) Promoter Polymorphisms Modulate PRNP Expression and May Be Responsible for Differences in Bovine Spongiform Encephalopathy Susceptibility
J. Biol. Chem. 2005 280: 37408-37414. First Published on September 1, 2005; doi:10.1074/jbc.M506361200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Francesca Cargnin, Adriano Flora, Simona Di Lascio, Elena Battaglioli, Renato Longhi, Francesco Clementi, and Diego Fornasari
PHOX2B Regulates Its Own Expression by a Transcriptional Auto-regulatory Mechanism
J. Biol. Chem. 2005 280: 37439-37448. First Published on September 6, 2005; doi:10.1074/jbc.M508368200 [Abstract] [Full Text] [PDF]  

Shujuan Chen, Deirdre Beaton, Nghia Nguyen, Kathy Senekeo-Effenberger, Erin Brace-Sinnokrak, Upendra Argikar, Rory P. Remmel, Jocelyn Trottier, Olivier Barbier, Joseph K. Ritter, and Robert H. Tukey
Tissue-specific, Inducible, and Hormonal Control of the Human UDP-Glucuronosyltransferase-1 (UGT1) Locus
J. Biol. Chem. 2005 280: 37547-37557. First Published on September 9, 2005; doi:10.1074/jbc.M506683200 [Abstract] [Full Text] [PDF]  

Emanuele Buratti, Antonia Brindisi, Maurizio Giombi, Sergio Tisminetzky, Youhna M. Ayala, and Francisco E. Baralle
TDP-43 Binds Heterogeneous Nuclear Ribonucleoprotein A/B through Its C-terminal Tail: AN IMPORTANT REGION FOR THE INHIBITION OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR EXON 9 SPLICING
J. Biol. Chem. 2005 280: 37572-37584. First Published on September 12, 2005; doi:10.1074/jbc.M505557200 [Abstract] [Full Text] [PDF]  

Stéphane Hausmann, Hisashi Koiwa, Shankarling Krishnamurthy, Michael Hampsey, and Stewart Shuman
Different Strategies for Carboxyl-terminal Domain (CTD) Recognition by Serine 5-specific CTD Phosphatases
J. Biol. Chem. 2005 280: 37681-37688. First Published on September 7, 2005; doi:10.1074/jbc.M505292200 [Abstract] [Full Text] [PDF]  

Emile van den Akker, Sabine Ano, Hsiu-Ming Shih, Ling-Chi Wang, Martine Pironin, Jorma J. Palvimo, Noora Kotaja, Olivier Kirsh, Anne Dejean, and Jacques Ghysdael
FLI-1 Functionally Interacts with PIASx{alpha}, a Member of the PIAS E3 SUMO Ligase Family
J. Biol. Chem. 2005 280: 38035-38046. First Published on September 7, 2005; doi:10.1074/jbc.M502938200 [Abstract] [Full Text] [PDF]  

Sylvain Daujat, Ulrike Zeissler, Tanja Waldmann, Nicole Happel, and Robert Schneider
HP1 Binds Specifically to Lys26-methylated Histone H1.4, whereas Simultaneous Ser27 Phosphorylation Blocks HP1 Binding
J. Biol. Chem. 2005 280: 38090-38095. First Published on August 28, 2005; doi:10.1074/jbc.C500229200 [Abstract] [Full Text] [PDF] [Supplemental Data]  


RNA: Structure, Metabolism, and Catalysis:

William F. Waas, Valérie de Crécy-Lagard, and Paul Schimmel
Discovery of a Gene Family Critical to Wyosine Base Formation in a Subset of Phenylalanine-specific Transfer RNAs
J. Biol. Chem. 2005 280: 37616-37622. First Published on September 13, 2005; doi:10.1074/jbc.M506939200 [Abstract] [Full Text] [PDF]  

Young-Chan Kim, William K. Russell, C. T. Ranjith-Kumar, Michael Thomson, David H. Russell, and C. Cheng Kao
Functional Analysis of RNA Binding by the Hepatitis C Virus RNA-dependent RNA Polymerase
J. Biol. Chem. 2005 280: 38011-38019. First Published on September 14, 2005; doi:10.1074/jbc.M508145200 [Abstract] [Full Text] [PDF]  


Protein Synthesis, Post-Translation Modification, and Degradation:

Philippe Marambaud, Haitian Zhao, and Peter Davies
Resveratrol Promotes Clearance of Alzheimer's Disease Amyloid-{beta} Peptides
J. Biol. Chem. 2005 280: 37377-37382. First Published on September 14, 2005; doi:10.1074/jbc.M508246200 [Abstract] [Full Text] [PDF]  

Andrey L. Karamyshev and Arthur E. Johnson
Selective SecA Association with Signal Sequences in Ribosome-bound Nascent Chains: A POTENTIAL ROLE FOR SecA IN RIBOSOME TARGETING TO THE BACTERIAL MEMBRANE
J. Biol. Chem. 2005 280: 37930-37940. First Published on August 23, 2005; doi:10.1074/jbc.M509100200 [Abstract] [Full Text] [PDF]  

Martin J. Gallagher, Wangzhen Shen, Luyan Song, and Robert L. Macdonald
Endoplasmic Reticulum Retention and Associated Degradation of a GABAA Receptor Epilepsy Mutation That Inserts an Aspartate in the M3 Transmembrane Segment of the {alpha}1 Subunit
J. Biol. Chem. 2005 280: 37995-38004. First Published on August 25, 2005; doi:10.1074/jbc.M508305200 [Abstract] [Full Text] [PDF]  

Frank Herrmann, Jaeho Lee, Mark T. Bedford, and Frank O. Fackelmayer
Dynamics of Human Protein Arginine Methyltransferase 1(PRMT1) in Vivo
J. Biol. Chem. 2005 280: 38005-38010. First Published on September 13, 2005; doi:10.1074/jbc.M502458200 [Abstract] [Full Text] [PDF] [Supplemental Data]  


Protein Structure and Folding:

Cihangir Duy and Jörg Fitter
Thermostability of Irreversible Unfolding {alpha}-Amylases Analyzed by Unfolding Kinetics
J. Biol. Chem. 2005 280: 37360-37365. First Published on September 2, 2005; doi:10.1074/jbc.M507530200 [Abstract] [Full Text] [PDF]  

Matthew J. Duncan, Elena L. Mann, Michael S. Cohen, Itzhak Ofek, Nathan Sharon, and Soman N. Abraham
The Distinct Binding Specificities Exhibited by Enterobacterial Type 1 Fimbriae Are Determined by Their Fimbrial Shafts
J. Biol. Chem. 2005 280: 37707-37716. First Published on August 23, 2005; doi:10.1074/jbc.M501249200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Casey E. Bohl, Duane D. Miller, Jiyun Chen, Charles E. Bell, and James T. Dalton
Structural Basis for Accommodation of Nonsteroidal Ligands in the Androgen Receptor
J. Biol. Chem. 2005 280: 37747-37754. First Published on August 29, 2005; doi:10.1074/jbc.M507464200 [Abstract] [Full Text] [PDF]  

Mahavir Singh, Marcin Krajewski, Aleksandra Mikolajka, and Tad A. Holak
Molecular Determinants for the Complex Formation between the Retinoblastoma Protein and LXCXE Sequences
J. Biol. Chem. 2005 280: 37868-37876. First Published on August 23, 2005; doi:10.1074/jbc.M504877200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Caroline Silve, Christophe Petrel, Christine Leroy, Henri Bruel, Eric Mallet, Didier Rognan, and Martial Ruat
Delineating a Ca2+ Binding Pocket within the Venus Flytrap Module of the Human Calcium-sensing Receptor
J. Biol. Chem. 2005 280: 37917-37923. First Published on September 7, 2005; doi:10.1074/jbc.M506263200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Philipp Beinker, Sandra Schlee, Rajeswari Auvula, and Jochen Reinstein
Biochemical Coupling of the Two Nucleotide Binding Domains of ClpB: COVALENT LINKAGE IS NOT A PREREQUISITE FOR CHAPERONE ACTIVITY
J. Biol. Chem. 2005 280: 37965-37973. First Published on September 13, 2005; doi:10.1074/jbc.M506672200 [Abstract] [Full Text] [PDF]  

Do Jin Kim, Kyoung Hoon Kim, Hyung Ho Lee, Sang Jae Lee, Jun Yong Ha, Hye Jin Yoon, and Se Won Suh
Crystal Structure of Lipoate-Protein Ligase A Bound with the Activated Intermediate: INSIGHTS INTO INTERACTION WITH LIPOYL DOMAINS
J. Biol. Chem. 2005 280: 38081-38089. First Published on September 2, 2005; doi:10.1074/jbc.M507284200 [Abstract] [Full Text] [PDF] [Supplemental Data]  


Enzyme Catalysis and Regulation:

Natasa Peric-Concha, Branko Borovicka, Paul F. Long, Daslav Hranueli, Peter G. Waterman, and Iain S. Hunter
Ablation of the otcC Gene Encoding a Post-polyketide Hydroxylase from the Oxytetracyline Biosynthetic Pathway in Streptomyces rimosus Results in Novel Polyketides with Altered Chain Length
J. Biol. Chem. 2005 280: 37455-37460. First Published on September 7, 2005; doi:10.1074/jbc.M503191200 [Abstract] [Full Text] [PDF]  

Matthew L. Hemming and Dennis J. Selkoe
Amyloid {beta}-Protein Is Degraded by Cellular Angiotensin-converting Enzyme (ACE) and Elevated by an ACE Inhibitor
J. Biol. Chem. 2005 280: 37644-37650. First Published on September 9, 2005; doi:10.1074/jbc.M508460200 [Abstract] [Full Text] [PDF]  

Kohji Okumura, Ai Ohno, Masanori Nishida, Kyozo Hayashi, Kiyoshi Ikeda, and Seiji Inoue
Mapping the Region of the {alpha}-Type Phospholipase A2 Inhibitor Responsible for Its Inhibitory Activity
J. Biol. Chem. 2005 280: 37651-37659. First Published on September 2, 2005; doi:10.1074/jbc.M507250200 [Abstract] [Full Text] [PDF]  

Guojun Zhao, Mei-Zhen Cui, Guozhang Mao, Yunzhou Dong, Jianxin Tan, Longsheng Sun, and Xuemin Xu
{gamma}-Cleavage Is Dependent on {zeta}-Cleavage during the Proteolytic Processing of Amyloid Precursor Protein within Its Transmembrane Domain
J. Biol. Chem. 2005 280: 37689-37697. First Published on September 12, 2005; doi:10.1074/jbc.M507993200 [Abstract] [Full Text] [PDF]  

Kai U. Walter, Katherina Vamvaca, and Donald Hilvert
An Active Enzyme Constructed from a 9-Amino Acid Alphabet
J. Biol. Chem. 2005 280: 37742-37746. First Published on September 6, 2005; doi:10.1074/jbc.M507210200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Fei Liu, Inge Grundke-Iqbal, Khalid Iqbal, Yoshiya Oda, Kazuhito Tomizawa, and Cheng-Xin Gong
Truncation and Activation of Calcineurin A by Calpain I in Alzheimer Disease Brain
J. Biol. Chem. 2005 280: 37755-37762. First Published on September 2, 2005; doi:10.1074/jbc.M507475200 [Abstract] [Full Text] [PDF]  

Ashok Kumar, Subburaman Mohan, Jacqueline Newton, Mark Rehage, Kiet Tran, David J. Baylink, and Xuezhong Qin
Pregnancy-associated Plasma Protein-A Regulates Myoblast Proliferation and Differentiation through an Insulin-like Growth Factor-dependent Mechanism
J. Biol. Chem. 2005 280: 37782-37789. First Published on August 22, 2005; doi:10.1074/jbc.M505278200 [Abstract] [Full Text] [PDF]  

Thomas Jank, Dirk J. Reinert, Torsten Giesemann, Georg E. Schulz, and Klaus Aktories
Change of the Donor Substrate Specificity of Clostridium difficile Toxin B by Site-directed Mutagenesis
J. Biol. Chem. 2005 280: 37833-37838. First Published on September 12, 2005; doi:10.1074/jbc.M506836200 [Abstract] [Full Text] [PDF]  

Vyacheslav M. Labunskyy, Andrew D. Ferguson, Dmitri E. Fomenko, Yogarany Chelliah, Dolph L. Hatfield, and Vadim N. Gladyshev
A Novel Cysteine-rich Domain of Sep15 Mediates the Interaction with UDP-glucose:Glycoprotein Glucosyltransferase
J. Biol. Chem. 2005 280: 37839-37845. First Published on August 29, 2005; doi:10.1074/jbc.M508685200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Jesús Oria-Hernández, Nallely Cabrera, Ruy Pérez-Montfort, and Leticia Ramírez-Silva
Pyruvate Kinase Revisited: THE ACTIVATING EFFECT OF K+
J. Biol. Chem. 2005 280: 37924-37929. First Published on September 7, 2005; doi:10.1074/jbc.M508490200 [Abstract] [Full Text] [PDF]  

Ute Bertsche, Eefjan Breukink, Thomas Kast, and Waldemar Vollmer
In Vitro Murein (Peptidoglycan) Synthesis by Dimers of the Bifunctional Transglycosylase-Transpeptidase PBP1B from Escherichia coli
J. Biol. Chem. 2005 280: 38096-38101. First Published on September 9, 2005; doi:10.1074/jbc.M508646200 [Abstract] [Full Text] [PDF]  


Metabolism and Bioenergetics:

William C. Orr, Svetlana N. Radyuk, Leena Prabhudesai, Dikran Toroser, Judith J. Benes, James M. Luchak, Robin J. Mockett, Igor Rebrin, J. Gregory Hubbard, and Rajindar S. Sohal
Overexpression of Glutamate-Cysteine Ligase Extends Life Span in Drosophila melanogaster
J. Biol. Chem. 2005 280: 37331-37338. First Published on September 7, 2005; doi:10.1074/jbc.M508272200 [Abstract] [Full Text] [PDF]  

Yeong-Renn Chen, Chwen-Lih Chen, Liwen Zhang, Kari B. Green-Church, and Jay L. Zweier
Superoxide Generation from Mitochondrial NADH Dehydrogenase Induces Self-inactivation with Specific Protein Radical Formation
J. Biol. Chem. 2005 280: 37339-37348. First Published on September 8, 2005; doi:10.1074/jbc.M503936200 [Abstract] [Full Text] [PDF]  

Masaaki Korenaga, Ting Wang, Yanchun Li, Lori A. Showalter, Tehsheng Chan, Jiaren Sun, and Steven A. Weinman
Hepatitis C Virus Core Protein Inhibits Mitochondrial Electron Transport and Increases Reactive Oxygen Species (ROS) Production
J. Biol. Chem. 2005 280: 37481-37488. First Published on September 8, 2005; doi:10.1074/jbc.M506412200 [Abstract] [Full Text] [PDF]  

Haruhisa Iguchi, Yukio Ikeda, Masashi Okamura, Toshiya Tanaka, Yasuyo Urashima, Hiroto Ohguchi, Shinobu Takayasu, Noriaki Kojima, Satoshi Iwasaki, Riuko Ohashi, Shuying Jiang, Go Hasegawa, Ryoichi X. Ioka, Kenta Magoori, Koichi Sumi, Takashi Maejima, Aoi Uchida, Makoto Naito, Timothy F. Osborne, Masashi Yanagisawa, Tokuo T. Yamamoto, Tatsuhiko Kodama, and Juro Sakai
SOX6 Attenuates Glucose-stimulated Insulin Secretion by Repressing PDX1 Transcriptional Actvity and Is Down-regulated in Hyperinsulinemic Obese Mice
J. Biol. Chem. 2005 280: 37669-37680. First Published on September 7, 2005; doi:10.1074/jbc.M505392200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Yukihiro Kimura, Naoki Mizusawa, Asako Ishii, Shigeaki Nakazawa, and Taka-aki Ono
Changes in Structural and Functional Properties of Oxygen-evolving Complex Induced by Replacement of D1-Glutamate 189 with Glutamine in Photosystem II: LIGATION OF GLUTAMATE 189 CARBOXYLATE TO THE MANGANESE CLUSTER
J. Biol. Chem. 2005 280: 37895-37900. First Published on September 12, 2005; doi:10.1074/jbc.M505887200 [Abstract] [Full Text] [PDF]  

Selvi Jeyaraj, Duaa Dakhlallah, Stephanie R. Hill, and Beth S. Lee
HuR Stabilizes Vacuolar H+-translocating ATPase mRNA during Cellular Energy Depletion
J. Biol. Chem. 2005 280: 37957-37964. First Published on September 9, 2005; doi:10.1074/jbc.M502883200 [Abstract] [Full Text] [PDF]  


Glycobiology and Extracellular Matrices:

Sandra Meyer, Ellis van Liempt, Anne Imberty, Yvette van Kooyk, Hildegard Geyer, Rudolf Geyer, and Irma van Die
DC-SIGN Mediates Binding of Dendritic Cells to Authentic Pseudo-LewisY Glycolipids of Schistosoma mansoni Cercariae, the First Parasite-specific Ligand of DC-SIGN
J. Biol. Chem. 2005 280: 37349-37359. First Published on September 9, 2005; doi:10.1074/jbc.M507100200 [Abstract] [Full Text] [PDF]  

Kiyotaka Fujita, Fusako Oura, Noriko Nagamine, Takane Katayama, Jun Hiratake, Kanzo Sakata, Hidehiko Kumagai, and Kenji Yamamoto
Identification and Molecular Cloning of a Novel Glycoside Hydrolase Family of Core 1 Type O-Glycan-specific Endo-{alpha}-N-acetylgalactosaminidase from Bifidobacterium longum
J. Biol. Chem. 2005 280: 37415-37422. First Published on September 1, 2005; doi:10.1074/jbc.M506874200 [Abstract] [Full Text] [PDF]  

Stéphane Sarrazin, David Bonnaffé, André Lubineau, and Hugues Lortat-Jacob
Heparan Sulfate Mimicry: A SYNTHETIC GLYCOCONJUGATE THAT RECOGNIZES THE HEPARIN BINDING DOMAIN OF INTERFERON-{gamma} INHIBITS THE CYTOKINE ACTIVITY
J. Biol. Chem. 2005 280: 37558-37564. First Published on September 9, 2005; doi:10.1074/jbc.M507729200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Costel C. Darie, Martin L. Biniossek, Mary A. Gawinowicz, Yelena Milgrom, Joerg O. Thumfart, Luca Jovine, Eveline S. Litscher, and Paul M. Wassarman
Mass Spectrometric Evidence That Proteolytic Processing of Rainbow Trout Egg Vitelline Envelope Proteins Takes Place on the Egg
J. Biol. Chem. 2005 280: 37585-37598. First Published on September 12, 2005; doi:10.1074/jbc.M506709200 [Abstract] [Full Text] [PDF]  

Eric C. Seales, Faheem M. Shaikh, Alencia V. Woodard-Grice, Pooja Aggarwal, Alexis C. McBrayer, Kristin M. Hennessy, and Susan L. Bellis
A Protein Kinase C/Ras/ERK Signaling Pathway Activates Myeloid Fibronectin Receptors by Altering {beta}1 Integrin Sialylation
J. Biol. Chem. 2005 280: 37610-37615. First Published on September 12, 2005; doi:10.1074/jbc.M508476200 [Abstract] [Full Text] [PDF]  

Eric P. Girardin, Sassan HajMohammadi, Béatrice Birmele, Armin Helisch, Nicholas W. Shworak, and Ariane I. de Agostini
Synthesis of Anticoagulantly Active Heparan Sulfate Proteoglycans by Glomerular Epithelial Cells Involves Multiple 3-O-Sulfotransferase Isoforms and a Limiting Precursor Pool
J. Biol. Chem. 2005 280: 38059-38070. First Published on August 17, 2005; doi:10.1074/jbc.M507997200 [Abstract] [Full Text] [PDF]  


Lipids and Lipoproteins:

Karin Athenstaedt and Günther Daum
Tgl4p and Tgl5p, Two Triacylglycerol Lipases of the Yeast Saccharomyces cerevisiae Are Localized to Lipid Particles
J. Biol. Chem. 2005 280: 37301-37309. First Published on August 31, 2005; doi:10.1074/jbc.M507261200 [Abstract] [Full Text] [PDF]  

Mia Sneck, Petri T. Kovanen, and Katariina Öörni
Decrease in pH Strongly Enhances Binding of Native, Proteolyzed, Lipolyzed, and Oxidized Low Density Lipoprotein Particles to Human Aortic Proteoglycans
J. Biol. Chem. 2005 280: 37449-37454. First Published on September 6, 2005; doi:10.1074/jbc.M508565200 [Abstract] [Full Text] [PDF]  

Zhaoyu Li, Luis B. Agellon, and Dennis E. Vance
Phosphatidylcholine Homeostasis and Liver Failure
J. Biol. Chem. 2005 280: 37798-37802. First Published on September 6, 2005; doi:10.1074/jbc.M508575200 [Abstract] [Full Text] [PDF]  

Kazuo Emoto, Hironori Inadome, Yasunori Kanaho, Shuh Narumiya, and Masato Umeda
Local Change in Phospholipid Composition at the Cleavage Furrow Is Essential for Completion of Cytokinesis
J. Biol. Chem. 2005 280: 37901-37907. First Published on September 14, 2005; doi:10.1074/jbc.M504282200 [Abstract] [Full Text] [PDF]  

Vanina Zaremberg, Consuelo Gajate, Luis M. Cacharro, Faustino Mollinedo, and Christopher R. McMaster
Cytotoxicity of an Anti-cancer Lysophospholipid through Selective Modification of Lipid Raft Composition
J. Biol. Chem. 2005 280: 38047-38058. First Published on September 9, 2005; doi:10.1074/jbc.M502849200 [Abstract] [Full Text] [PDF]  

Laure Dumont, Thomas Gautier, Jean-Paul Pais de Barros, Hélène Laplanche, Denis Blache, Patrick Ducoroy, Jamila Fruchart, Jean-Charles Fruchart, Philippe Gambert, David Masson, and Laurent Lagrost
Molecular Mechanism of the Blockade of Plasma Cholesteryl Ester Transfer Protein by Its Physiological Inhibitor Apolipoprotein CI
J. Biol. Chem. 2005 280: 38108-38116. First Published on September 13, 2005; doi:10.1074/jbc.M504678200 [Abstract] [Full Text] [PDF]  


Membrane Transport, Structure, Function, and Biogenesis:

Hideyo Sato, Ayako Shiiya, Mayumi Kimata, Kanako Maebara, Michiko Tamba, Yuki Sakakura, Nobuo Makino, Fumihiro Sugiyama, Ken-ichi Yagami, Takashi Moriguchi, Satoru Takahashi, and Shiro Bannai
Redox Imbalance in Cystine/Glutamate Transporter-deficient Mice
J. Biol. Chem. 2005 280: 37423-37429. First Published on September 6, 2005; doi:10.1074/jbc.M506439200 [Abstract] [Full Text] [PDF]  

Jianquan Li, Zhongping Dai, Deirdre Jana, David J. E. Callaway, and Zimei Bu
Ezrin Controls the Macromolecular Complexes Formed between an Adapter Protein Na+/H+ Exchanger Regulatory Factor and the Cystic Fibrosis Transmembrane Conductance Regulator
J. Biol. Chem. 2005 280: 37634-37643. First Published on August 28, 2005; doi:10.1074/jbc.M502305200 [Abstract] [Full Text] [PDF]  

Irina Lubarski, Kaarina Pihakaski-Maunsbach, Steven J. D. Karlish, Arvid B. Maunsbach, and Haim Garty
Interaction with the Na,K-ATPase and Tissue Distribution of FXYD5 (Related to Ion Channel)
J. Biol. Chem. 2005 280: 37717-37724. First Published on September 7, 2005; doi:10.1074/jbc.M506397200 [Abstract] [Full Text] [PDF]  

Mohamed Chami, Ingrid Guilvout, Marco Gregorini, Hervé W. Rémigy, Shirley A. Müller, Marielle Valerio, Andreas Engel, Anthony P. Pugsley, and Nicolas Bayan
Structural Insights into the Secretin PulD and Its Trypsin-resistant Core
J. Biol. Chem. 2005 280: 37732-37741. First Published on August 29, 2005; doi:10.1074/jbc.M504463200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Carsten Schmitz, Maxim V. Dorovkov, Xiaoyun Zhao, Bennett J. Davenport, Alexey G. Ryazanov, and Anne-Laure Perraud
The Channel Kinases TRPM6 and TRPM7 Are Functionally Nonredundant
J. Biol. Chem. 2005 280: 37763-37771. First Published on September 2, 2005; doi:10.1074/jbc.M509175200 [Abstract] [Full Text] [PDF]  

Mark Larance, Georg Ramm, Jacqueline Stöckli, Ellen M. van Dam, Stephanie Winata, Valerie Wasinger, Fiona Simpson, Michael Graham, Jagath R. Junutula, Michael Guilhaus, and David E. James
Characterization of the Role of the Rab GTPase-activating Protein AS160 in Insulin-regulated GLUT4 Trafficking
J. Biol. Chem. 2005 280: 37803-37813. First Published on September 8, 2005; doi:10.1074/jbc.M503897200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Zhan-Yun Guo, Song Lin, Jennifer A. Heinen, Catherine C. Y. Chang, and Ta-Yuan Chang
The Active Site His-460 of Human Acyl-coenzyme A:Cholesterol Acyltransferase 1 Resides in a Hitherto Undisclosed Transmembrane Domain
J. Biol. Chem. 2005 280: 37814-37826. First Published on September 8, 2005; doi:10.1074/jbc.M508384200 [Abstract] [Full Text] [PDF]  

Christian G. Riedel, Massimiliano Mazza, Peter Maier, Roman Körner, and Michael Knop
Differential Requirement for Phospholipase D/Spo14 and Its Novel Interactor Sma1 for Regulation of Exocytotic Vesicle Fusion in Yeast Meiosis
J. Biol. Chem. 2005 280: 37846-37852. First Published on September 7, 2005; doi:10.1074/jbc.M504244200 [Abstract] [Full Text] [PDF]  

Paul S. Miller, Helena M. A. Da Silva, and Trevor G. Smart
Molecular Basis for Zinc Potentiation at Strychnine-sensitive Glycine Receptors
J. Biol. Chem. 2005 280: 37877-37884. First Published on September 6, 2005; doi:10.1074/jbc.M508303200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Zheng Liu, Ruiwu Wang, Jing Zhang, S. R. Wayne Chen, and Terence Wagenknecht
Localization of a Disease-associated Mutation Site in the Three-dimensional Structure of the Cardiac Muscle Ryanodine Receptor
J. Biol. Chem. 2005 280: 37941-37947. First Published on September 11, 2005; doi:10.1074/jbc.M505714200 [Abstract] [Full Text] [PDF]  


Mechanisms Of Signal Transduction:

Patrícia A. Madureira, Paulo Matos, Inês Soeiro, Linda K. Dixon, J. Pedro Simas, and Eric W.-F. Lam
Murine {gamma}-Herpesvirus 68 Latency Protein M2 Binds to Vav Signaling Proteins and Inhibits B-cell Receptor-induced Cell Cycle Arrest and Apoptosis in WEHI-231 B Cells
J. Biol. Chem. 2005 280: 37310-37318. First Published on September 2, 2005; doi:10.1074/jbc.M507478200 [Abstract] [Full Text] [PDF]  

Lieve Verlinden, Guy Eelen, Ine Beullens, Mark Van Camp, Paul Van Hummelen, Kristof Engelen, Ruth Van Hellemont, Kathleen Marchal, Bart De Moor, Floris Foijer, Hein Te Riele, Monique Beullens, Mathieu Bollen, Chantal Mathieu, Roger Bouillon, and Annemieke Verstuyf
Characterization of the Condensin Component Cnap1 and Protein Kinase Melk as Novel E2F Target Genes Down-regulated by 1,25-Dihydroxyvitamin D3
J. Biol. Chem. 2005 280: 37319-37330. First Published on September 6, 2005; doi:10.1074/jbc.M503587200 [Abstract] [Full Text] [PDF]  

Zaiping Liu, Hongbing Li, Mathieu Derouet, Jorge Filmus, Eric C. LaCasse, Robert G. Korneluk, Robert S. Kerbel, and Kirill V. Rosen
ras Oncogene Triggers Up-regulation of cIAP2 and XIAP in Intestinal Epithelial Cells: EPIDERMAL GROWTH FACTOR RECEPTOR-DEPENDENT AND -INDEPENDENT MECHANISMS OF ras-INDUCED TRANSFORMATION
J. Biol. Chem. 2005 280: 37383-37392. First Published on August 22, 2005; doi:10.1074/jbc.M503724200 [Abstract] [Full Text] [PDF]  

Cora Weigert, Anita M. Hennige, Tasja Brischmann, Alexander Beck, Klaus Moeschel, Myriam Schaüble, Katrin Brodbeck, Hans-Ulrich Häring, Erwin D. Schleicher, and Rainer Lehmann
The Phosphorylation of Ser318 of Insulin Receptor Substrate 1 Is Not per se Inhibitory in Skeletal Muscle Cells but Is Necessary to Trigger the Attenuation of the Insulin-stimulated Signal
J. Biol. Chem. 2005 280: 37393-37399. First Published on August 29, 2005; doi:10.1074/jbc.M506134200 [Abstract] [Full Text] [PDF]  

Jasna A. Marjanovic, Zhenyu Li, Aleksandra Stojanovic, and Xiaoping Du
Stimulatory Roles of Nitric-oxide Synthase 3 and Guanylyl Cyclase in Platelet Activation
J. Biol. Chem. 2005 280: 37430-37438. First Published on September 6, 2005; doi:10.1074/jbc.M506518200 [Abstract] [Full Text] [PDF]  

Jennifer N. Wingard, Jenny Chan, Ivan Bosanac, Françoise Haeseleer, Krzysztof Palczewski, Mitsuhiko Ikura, and James B. Ames
Structural Analysis of Mg2+ and Ca2+ Binding to CaBP1, a Neuron-specific Regulator of Calcium Channels
J. Biol. Chem. 2005 280: 37461-37470. First Published on September 7, 2005; doi:10.1074/jbc.M508541200 [Abstract] [Full Text] [PDF]  

Tanya Landsman and David J. Waxman
Role of the Cytokine-induced SH2 Domain-containing Protein CIS in Growth Hormone Receptor Internalization
J. Biol. Chem. 2005 280: 37471-37480. First Published on September 8, 2005; doi:10.1074/jbc.M504125200 [Abstract] [Full Text] [PDF]  

Linda A. Barbour, Shaikh Mizanoor Rahman, Inga Gurevich, J. Wayne Leitner, Stephanie J. Fischer, Michael D. Roper, Trina A. Knotts, Yen Vo, Carrie E. McCurdy, Shoshana Yakar, Derek LeRoith, C. Ronald Kahn, Lewis C. Cantley, Jacob E. Friedman, and Boris Draznin
Increased P85{alpha} Is a Potent Negative Regulator of Skeletal Muscle Insulin Signaling and Induces in Vivo Insulin Resistance Associated with Growth Hormone Excess
J. Biol. Chem. 2005 280: 37489-37494. First Published on September 8, 2005; doi:10.1074/jbc.M506967200 [Abstract] [Full Text] [PDF]  

Symone M. San Miguel, Malka Namdar-Attar, Tommy Noh, Baruch Frenkel, and Itai Bab
ERK1/2-activated de Novo Mapkapk2 Synthesis Is Essential for Osteogenic Growth Peptide Mitogenic Signaling in Osteoblastic Cells
J. Biol. Chem. 2005 280: 37495-37502. First Published on September 2, 2005; doi:10.1074/jbc.M503861200 [Abstract] [Full Text] [PDF]  

Friederike Hüttenrauch, Beatrix Pollok-Kopp, and Martin Oppermann
G Protein-coupled Receptor Kinases Promote Phosphorylation and {beta}-Arrestin-mediated Internalization of CCR5 Homo- and Hetero-oligomers
J. Biol. Chem. 2005 280: 37503-37515. First Published on September 6, 2005; doi:10.1074/jbc.M500535200 [Abstract] [Full Text] [PDF]  

Laurent Désiré, Jérôme Bourdin, Nadia Loiseau, Hélène Peillon, Virginie Picard, Catherine De Oliveira, Florence Bachelot, Bertrand Leblond, Thierry Taverne, Eric Beausoleil, Sandrine Lacombe, Dominique Drouin, and Fabien Schweighoffer
RAC1 Inhibition Targets Amyloid Precursor Protein Processing by {gamma}-Secretase and Decreases A{beta} Production in Vitro and in Vivo
J. Biol. Chem. 2005 280: 37516-37525. First Published on September 8, 2005; doi:10.1074/jbc.M507913200 [Abstract] [Full Text] [PDF]  

Erzsebet Szatmari, Agata Habas, Peng Yang, Jing-Juan Zheng, Theo Hagg, and Michal Hetman
A Positive Feedback Loop between Glycogen Synthase Kinase 3{beta} and Protein Phosphatase 1 after Stimulation of NR2B NMDA Receptors in Forebrain Neurons
J. Biol. Chem. 2005 280: 37526-37535. First Published on September 9, 2005; doi:10.1074/jbc.M502699200 [Abstract] [Full Text] [PDF]  

Sasmita Mishra, Jyoti P. Mishra, Katrina Gee, Dan C. McManus, Eric C. LaCasse, and Ashok Kumar
Distinct Role of Calmodulin and Calmodulin-dependent Protein Kinase-II in Lipopolysaccharide and Tumor Necrosis Factor-{alpha}-mediated Suppression of Apoptosis and Antiapoptotic c-IAP2 Gene Expression in Human Monocytic Cells
J. Biol. Chem. 2005 280: 37536-37546. First Published on September 9, 2005; doi:10.1074/jbc.M504971200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Oleh Pochynyuk, Alexander Staruschenko, Qiusheng Tong, Jorge Medina, and James D. Stockand
Identification of a Functional Phosphatidylinositol 3,4,5-Trisphosphate Binding Site in the Epithelial Na+ Channel
J. Biol. Chem. 2005 280: 37565-37571. First Published on September 9, 2005; doi:10.1074/jbc.M509071200 [Abstract] [Full Text] [PDF]  

Geng-Xian Shi, Jiahuai Han, and Douglas A. Andres
Rin GTPase Couples Nerve Growth Factor Signaling to p38 and b-Raf/ERK Pathways to Promote Neuronal Differentiation
J. Biol. Chem. 2005 280: 37599-37609. First Published on September 12, 2005; doi:10.1074/jbc.M507364200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Josep Lluis Parra, Maria Buxadé, and Christopher G. Proud
Features of the Catalytic Domains and C Termini of the MAPK Signal-integrating Kinases Mnk1 and Mnk2 Determine Their Differing Activities and Regulatory Properties
J. Biol. Chem. 2005 280: 37623-37633. First Published on September 14, 2005; doi:10.1074/jbc.M508356200 [Abstract] [Full Text] [PDF]  

Aiko Nakashima, Takenobu Katagiri, and Masato Tamura
Cross-talk between Wnt and Bone Morphogenetic Protein 2 (BMP-2) Signaling in Differentiation Pathway of C2C12 Myoblasts
J. Biol. Chem. 2005 280: 37660-37668. First Published on September 2, 2005; doi:10.1074/jbc.M504612200 [Abstract] [Full Text] [PDF]  

Sunghyun Kang, Huiming Li, Anjana Rao, and Patrick G. Hogan
Inhibition of the Calcineurin-NFAT Interaction by Small Organic Molecules Reflects Binding at an Allosteric Site
J. Biol. Chem. 2005 280: 37698-37706. First Published on September 7, 2005; doi:10.1074/jbc.M502247200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Takahisa Takino, Mitsutoshi Nakada, Hisashi Miyamori, Yumi Watanabe, Tokiharu Sato, Davaakhuu Gantulga, Katsuji Yoshioka, Kenneth M. Yamada, and Hiroshi Sato
JSAP1/JIP3 Cooperates with Focal Adhesion Kinase to Regulate c-Jun N-terminal Kinase and Cell Migration
J. Biol. Chem. 2005 280: 37772-37781. First Published on September 2, 2005; doi:10.1074/jbc.M505241200 [Abstract] [Full Text] [PDF]  

Kostas D. Katsanakis and Tahir S. Pillay
Cross-talk between the Two Divergent Insulin Signaling Pathways Is Revealed by the Protein Kinase B (Akt)-mediated Phosphorylation of Adapter Protein APS on Serine 588
J. Biol. Chem. 2005 280: 37827-37832. First Published on September 1, 2005; doi:10.1074/jbc.M505959200 [Abstract] [Full Text] [PDF]  

Liang-Nian Song and Edward P. Gelmann
Interaction of {beta}-Catenin and TIF2/GRIP1 in Transcriptional Activation by the Androgen Receptor
J. Biol. Chem. 2005 280: 37853-37867. First Published on September 1, 2005; doi:10.1074/jbc.M503850200 [Abstract] [Full Text] [PDF]  

Céline Tárrega, Pablo Ríos, Rocío Cejudo-Marín, Carmen Blanco-Aparicio, Lieke van den Berk, Jan Schepens, Wiljan Hendriks, Lydia Tabernero, and Rafael Pulido
ERK2 Shows a Restrictive and Locally Selective Mechanism of Recognition by Its Tyrosine Phosphatase Inactivators Not Shared by Its Activator MEK1
J. Biol. Chem. 2005 280: 37885-37894. First Published on September 7, 2005; doi:10.1074/jbc.M504366200 [Abstract] [Full Text] [PDF]  

Adam F. Odell, Judith L. Scott, and Dirk F. Van Helden
Epidermal Growth Factor Induces Tyrosine Phosphorylation, Membrane Insertion, and Activation of Transient Receptor Potential Channel 4
J. Biol. Chem. 2005 280: 37974-37987. First Published on September 6, 2005; doi:10.1074/jbc.M503646200 [Abstract] [Full Text] [PDF]  

Jian-Jiang Hao, Jianwei Zhu, Kang Zhou, Nicole Smith, and Xi Zhan
The Coiled-coil Domain Is Required for HS1 to Bind to F-actin and Activate Arp2/3 Complex
J. Biol. Chem. 2005 280: 37988-37994. First Published on September 11, 2005; doi:10.1074/jbc.M504552200 [Abstract] [Full Text] [PDF]  

Masaya Yamamoto, Jeremy D. Clark, Johanne V. Pastor, Prem Gurnani, Animesh Nandi, Hiroshi Kurosu, Masayoshi Miyoshi, Yasushi Ogawa, Diego H. Castrillon, Kevin P. Rosenblatt, and Makoto Kuro-o
Regulation of Oxidative Stress by the Anti-aging Hormone Klotho
J. Biol. Chem. 2005 280: 38029-38034. First Published on September 26, 2005; doi:10.1074/jbc.M509039200 [Abstract] [Full Text] [PDF] [Summary]  

Najmoutin G. Abdulaev, Tony Ngo, Cheng Zhang, Andy Dinh, Danielle M. Brabazon, Kevin D. Ridge, and John P. Marino
Heterotrimeric G-protein {alpha}-Subunit Adopts a "Preactivated" Conformation When Associated with {beta}{gamma}-Subunits
J. Biol. Chem. 2005 280: 38071-38080. First Published on August 29, 2005; doi:10.1074/jbc.M505259200 [Abstract] [Full Text] [PDF] [Supplemental Data]  

Kenneth K. W. To and L. Eric Huang
Suppression of Hypoxia-inducible Factor 1{alpha} (HIF-1{alpha}) Transcriptional Activity by the HIF Prolyl Hydroxylase EGLN1
J. Biol. Chem. 2005 280: 38102-38107. First Published on September 12, 2005; doi:10.1074/jbc.M504342200 [Abstract] [Full Text] [PDF]  


Molecular Basis Of Cell and Developmental Biology:

Jian Wang, Vikram Devgan, Marcella Corrado, Nita S. Prabhu, Wafik S. El-Deiry, Carlo Riccardi, Pier Paolo Pandolfi, Caterina Missero, and G. Paolo Dotto
Glucocorticoid-induced Tumor Necrosis Factor Receptor Is a p21Cip1/WAF1 Transcriptional Target Conferring Resistance of Keratinocytes to UV Light-induced Apoptosis
J. Biol. Chem. 2005 280: 37725-37731. First Published on September 9, 2005; doi:10.1074/jbc.M507976200 [Abstract] [Full Text] [PDF]  

Qize Wei
Pitx2a Binds to Human Papillomavirus Type 18 E6 Protein and Inhibits E6-mediated P53 Degradation in HeLa Cells
J. Biol. Chem. 2005 280: 37790-37797. First Published on August 29, 2005; doi:10.1074/jbc.M502974200 [Abstract] [Full Text] [PDF]  

Il-Man Kim, Yan Zhou, Sneha Ramakrishna, Douglas E. Hughes, Julian Solway, Robert H. Costa, and Vladimir V. Kalinichenko
Functional Characterization of Evolutionarily Conserved DNA Regions in Forkhead Box F1 Gene Locus
J. Biol. Chem. 2005 280: 37908-37916. First Published on September 6, 2005; doi:10.1074/jbc.M506531200 [Abstract] [Full Text] [PDF]  

Ryuji X. Yamada, Norio Matsuki, and Yuji Ikegaya
cAMP Differentially Regulates Axonal and Dendritic Development of Dentate Granule Cells
J. Biol. Chem. 2005 280: 38020-38028. First Published on September 9, 2005; doi:10.1074/jbc.M503800200 [Abstract] [Full Text] [PDF] [Supplemental Data]  


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