JBC -- Table of Contents (Mar 4 2005, 280, (9))

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Nicole Kresge, Robert D. Simoni, and Robert L. Hill: The Fruits of Collaboration: Chromatography, Amino Acid Analyzers, and the Chemical Structure of Ribonuclease by William H. Stein and Stanford Moore
CHROMATOGRAPHY OF AMINO ACIDS ON STARCH COLUMNS. SEPARATION OF PHENYLALANINE, LEUCINE, ISOLEUCINE, METHIONINE, TYROSINE, AND VALINE (William H. Stein and Stanford Moore J. Biol. Chem. 176, 337-365)
PHOTOMETRIC NINHYDRIN METHOD FOR USE IN THE CHROMATOGRAPHY OF AMINO ACIDS (Stanford Moore and William H. Stein J. Biol. Chem. 176, 367-388)
J. Biol. Chem. 2005 280: e6. [Full Text]

Minireviews:

Daniel B. Rifkin: Latent Transforming Growth Factor- ${beta}$ (TGF- ${beta}$ ) Binding Proteins: Orchestrators of TGF- ${beta}$ Availability
J. Biol. Chem. 2005 280: 7409-7412. First Published on December 16, 2004; doi:10.1074/jbc.R400029200 [Full Text] [PDF]

DNA: Replication, Repair, and Recombination:

Emmanuel Dauty and A. S. Verkman: Actin Cytoskeleton as the Principal Determinant of Size-dependent DNA Mobility in Cytoplasm: A NEW BARRIER FOR NON-VIRAL GENE DELIVERY
J. Biol. Chem. 2005 280: 7823-7828. First Published on January 4, 2005; doi:10.1074/jbc.M412374200 [Abstract] [Full Text] [PDF]

Rohit Prakash, Lumir Krejci, Stephen Van Komen, Kirsten Anke Schürer, Wilfried Kramer, and Patrick Sung: Saccharomyces cerevisiae MPH1 Gene, Required for Homologous Recombination-mediated Mutation Avoidance, Encodes a 3' to 5' DNA Helicase
J. Biol. Chem. 2005 280: 7854-7860. First Published on January 4, 2005; doi:10.1074/jbc.M413898200 [Abstract] [Full Text] [PDF]

Thale C. Jarvis, Amber A. Beaudry, James M. Bullard, Nebojsa Janjic, and Charles S. McHenry: Reconstitution of a Minimal DNA Replicase from Pseudomonas aeruginosa and Stimulation by Non-cognate Auxiliary Factors
J. Biol. Chem. 2005 280: 7890-7900. First Published on December 15, 2004; doi:10.1074/jbc.M412263200 [Abstract] [Full Text] [PDF]

Kerry L. Williams, Yijun Zhang, Nick Shkriabai, Rajeshri G. Karki, Marc C. Nicklaus, Nana Kotrikadze, Sonja Hess, Stuart F. J. Le Grice, Robert Craigie, Vinay K. Pathak, and Mamuka Kvaratskhelia: Mass Spectrometric Analysis of the HIV-1 Integrase-Pyridoxal 5'-Phosphate Complex Reveals a New Binding Site for a Nucleotide Inhibitor
J. Biol. Chem. 2005 280: 7949-7955. First Published on December 22, 2004; doi:10.1074/jbc.M413579200 [Abstract] [Full Text] [PDF]

Assaf Friedler, Dmitry B. Veprintsev, Trevor Rutherford, Karoly I. von Glos, and Alan R. Fersht: Binding of Rad51 and Other Peptide Sequences to a Promiscuous, Highly Electrostatic Binding Site in p53
J. Biol. Chem. 2005 280: 8051-8059. First Published on December 20, 2004; doi:10.1074/jbc.M411176200 [Abstract] [Full Text] [PDF]

Ayumi Kudoh, Masatoshi Fujita, Lumin Zhang, Noriko Shirata, Tohru Daikoku, Yutaka Sugaya, Hiroki Isomura, Yukihiro Nishiyama, and Tatsuya Tsurumi: Epstein-Barr Virus Lytic Replication Elicits ATM Checkpoint Signal Transduction While Providing an S-phase-like Cellular Environment
J. Biol. Chem. 2005 280: 8156-8163. First Published on December 15, 2004; doi:10.1074/jbc.M411405200 [Abstract] [Full Text] [PDF]

Kaushik Ghosh, Chi Kong Lau, Feng Guo, Anca M. Segall, and Gregory D. Van Duyne: Peptide Trapping of the Holliday Junction Intermediate in Cre-loxP Site-specific Recombination
J. Biol. Chem. 2005 280: 8290-8299. First Published on December 8, 2004; doi:10.1074/jbc.M411668200 [Abstract] [Full Text] [PDF]

Genes: Structure and Regulation:

Jiali Li, Parinaz C. Pircher, Ira G. Schulman, and Stefan K. Westin: Regulation of Complement C3 Expression by the Bile Acid Receptor FXR
J. Biol. Chem. 2005 280: 7427-7434. First Published on December 7, 2004; doi:10.1074/jbc.M411473200 [Abstract] [Full Text] [PDF]

Michael L. Goodson, Brian A. Jonas, and Martin L. Privalsky: Alternative mRNA Splicing of SMRT Creates Functional Diversity by Generating Corepressor Isoforms with Different Affinities for Different Nuclear Receptors
J. Biol. Chem. 2005 280: 7493-7503. First Published on January 4, 2005; doi:10.1074/jbc.M411514200 [Abstract] [Full Text] [PDF]

Sungeun Hong, Inchul Choi, Jong-Min Woo, Jungsu Oh, Taewan Kim, Eunyoung Choi, Tae-Wan Kim, Yong-Keun Jung, Do Han Kim, Choong-Hyun Sun, Gwan-Su Yi, Edward M. Eddy, and Chunghee Cho: Identification and Integrative Analysis of 28 Novel Genes Specifically Expressed and Developmentally Regulated in Murine Spermatogenic Cells
J. Biol. Chem. 2005 280: 7685-7693. First Published on December 21, 2004; doi:10.1074/jbc.M412444200 [Abstract] [Full Text] [PDF] [Supplemental data]

Claudia S. Hofmann, Xiaobo Wang, Christopher P. Sullivan, Paul Toselli, Phillip J. Stone, Sean E. McLean, Robert P. Mecham, Barbara M. Schreiber, and Gail E. Sonenshein: B-Myb Represses Elastin Gene Expression in Aortic Smooth Muscle Cells
J. Biol. Chem. 2005 280: 7694-7701. First Published on December 21, 2004; doi:10.1074/jbc.M412501200 [Abstract] [Full Text] [PDF]

Abdelaziz En-Nia, Emek Yilmaz, Uwe Klinge, David H. Lovett, Ioannis Stefanidis, and Peter R. Mertens: Transcription Factor YB-1 Mediates DNA Polymerase ${alpha}$ Gene Expression
J. Biol. Chem. 2005 280: 7702-7711. First Published on December 21, 2004; doi:10.1074/jbc.M413353200 [Abstract] [Full Text] [PDF]

Stéphane Leung-Theung-Long, Emmanuelle Roulet, Pascal Clerc, Chantal Escrieut, Sophie Marchal-Victorion, Beate Ritz-Laser, Jacques Philippe, Lucien Pradayrol, Catherine Seva, Daniel Fourmy, and Marlène Dufresne: Essential Interaction of Egr-1 at an Islet-specific Response Element for Basal and Gastrin-dependent Glucagon Gene Transactivation in Pancreatic ${alpha}$ -Cells
J. Biol. Chem. 2005 280: 7976-7984. First Published on December 14, 2004; doi:10.1074/jbc.M407485200 [Abstract] [Full Text] [PDF]

Eva Estébanez-Perpiñá, Jamie M. R. Moore, Ellena Mar, Edson Delgado-Rodrigues, Phuong Nguyen, John D. Baxter, Benjamin M. Buehrer, Paul Webb, Robert J. Fletterick, and R. Kiplin Guy: The Molecular Mechanisms of Coactivator Utilization in Ligand-dependent Transactivation by the Androgen Receptor
J. Biol. Chem. 2005 280: 8060-8068. First Published on November 24, 2004; doi:10.1074/jbc.M407046200 [Abstract] [Full Text] [PDF] [Suplemental Data]

Thomas A. Hughes and Hugh J. M. Brady: Expression of axin2 Is Regulated by the Alternative 5'-Untranslated Regions of Its mRNA
J. Biol. Chem. 2005 280: 8581-8588. First Published on December 16, 2004; doi:10.1074/jbc.M410806200 [Abstract] [Full Text] [PDF]

RNA: Structure, Metabolism, and Catalysis:

Maria Antal, Valérie Bordeau, Véronique Douchin, and Brice Felden: A Small Bacterial RNA Regulates a Putative ABC Transporter
J. Biol. Chem. 2005 280: 7901-7908. First Published on December 22, 2004; doi:10.1074/jbc.M413071200 [Abstract] [Full Text] [PDF]

Protein Synthesis, Post-Translation Modification, and Degradation:

Heather Snyder, Kwame Mensah, Cindy Hsu, Makoto Hashimoto, Irina G. Surgucheva, Barry Festoff, Andrei Surguchov, Eliazer Masliah, Andreas Matouschek, and Benjamin Wolozin: ${beta}$ -Synuclein Reduces Proteasomal Inhibition by ${alpha}$ -Synuclein but Not ${gamma}$ -Synuclein
J. Biol. Chem. 2005 280: 7562-7569. First Published on December 9, 2004; doi:10.1074/jbc.M412887200 [Abstract] [Full Text] [PDF]

Neil Kubica, Douglas R. Bolster, Peter A. Farrell, Scot R. Kimball, and Leonard S. Jefferson: Resistance Exercise Increases Muscle Protein Synthesis and Translation of Eukaryotic Initiation Factor 2B ${epsilon}$ mRNA in a Mammalian Target of Rapamycin-dependent Manner
J. Biol. Chem. 2005 280: 7570-7580. First Published on December 10, 2004; doi:10.1074/jbc.M413732200 [Abstract] [Full Text] [PDF]

Markus Welcker and Bruce E. Clurman: The SV40 Large T Antigen Contains a Decoy Phosphodegron That Mediates Its Interactions with Fbw7/hCdc4
J. Biol. Chem. 2005 280: 7654-7658. First Published on December 20, 2004; doi:10.1074/jbc.M413377200 [Abstract] [Full Text] [PDF] [Summary]

Jianhua Yang, Koichiro Ishimori, and Mark R. O'Brian: Two Heme Binding Sites Are Involved in the Regulated Degradation of the Bacterial Iron Response Regulator (Irr) Protein
J. Biol. Chem. 2005 280: 7671-7676. First Published on December 21, 2004; doi:10.1074/jbc.M411664200 [Abstract] [Full Text] [PDF]

Astrid Kragt, Tineke Voorn-Brouwer, Marlene van den Berg, and Ben Distel: The Saccharomyces cerevisiae Peroxisomal Import Receptor Pex5p Is Monoubiquitinated in Wild Type Cells
J. Biol. Chem. 2005 280: 7867-7874. First Published on January 4, 2005; doi:10.1074/jbc.M413553200 [Abstract] [Full Text] [PDF]

Naoko Yagishita, Kinuko Ohneda, Tetsuya Amano, Satoshi Yamasaki, Akiko Sugiura, Kaneyuki Tsuchimochi, Hiroshi Shin, Ko-ichi Kawahara, Osamu Ohneda, Tomohiko Ohta, Sakae Tanaka, Masayuki Yamamoto, Ikuro Maruyama, Kusuki Nishioka, Akiyoshi Fukamizu, and Toshihiro Nakajima: Essential Role of Synoviolin in Embryogenesis
J. Biol. Chem. 2005 280: 7909-7916. First Published on December 20, 2004; doi:10.1074/jbc.M410863200 [Abstract] [Full Text] [PDF]

Wei Li, Elliot L. Hertzberg, and David C. Spray: Regulation of Connexin43-Protein Binding in Astrocytes in Response to Chemical Ischemia/Hypoxia
J. Biol. Chem. 2005 280: 7941-7948. First Published on December 22, 2004; doi:10.1074/jbc.M410548200 [Abstract] [Full Text] [PDF]

Felicia Miller, Alex Kentsis, Roman Osman, and Zhen-Qiang Pan: Inactivation of VHL by Tumorigenic Mutations That Disrupt Dynamic Coupling of the pVHL·Hypoxia-inducible Transcription Factor-1 ${alpha}$ Complex
J. Biol. Chem. 2005 280: 7985-7996. First Published on December 20, 2004; doi:10.1074/jbc.M413160200 [Abstract] [Full Text] [PDF]

Liang Feng, Kelly Sheppard, Debra Tumbula-Hansen, and Dieter Söll: Gln-tRNA^Gln Formation from Glu-tRNA^Gln Requires Cooperation of an Asparaginase and a Glu-tRNA^Gln Kinase
J. Biol. Chem. 2005 280: 8150-8155. First Published on December 16, 2004; doi:10.1074/jbc.M411098200 [Abstract] [Full Text] [PDF]

Hiroyuki Michiue, Kazuhito Tomizawa, Fan-Yan Wei, Masayuki Matsushita, Yun-Fei Lu, Tomotsugu Ichikawa, Takashi Tamiya, Isao Date, and Hideki Matsui: The NH₂ Terminus of Influenza Virus Hemagglutinin-2 Subunit Peptides Enhances the Antitumor Potency of Polyarginine-mediated p53 Protein Transduction
J. Biol. Chem. 2005 280: 8285-8289. First Published on December 16, 2004; doi:10.1074/jbc.M412430200 [Abstract] [Full Text] [PDF]

Michael J. Wichroski, Kozi Ichiyama, and Tariq M. Rana: Analysis of HIV-1 Viral Infectivity Factor-mediated Proteasome-dependent Depletion of APOBEC3G: CORRELATING FUNCTION AND SUBCELLULAR LOCALIZATION
J. Biol. Chem. 2005 280: 8387-8396. First Published on November 10, 2004; doi:10.1074/jbc.M408048200 [Abstract] [Full Text] [PDF]

Genomics, Proteomics, and Bioinformatics:

Gareth L. A. H. Jones, Elizabeth Sang, Catharine Goddard, Russell J. Mortishire-Smith, Brian C. Sweatman, John N. Haselden, Kay Davies, Andrew A. Grace, Kieran Clarke, and Julian L. Griffin: A Functional Analysis of Mouse Models of Cardiac Disease through Metabolic Profiling
J. Biol. Chem. 2005 280: 7530-7539. First Published on November 16, 2004; doi:10.1074/jbc.M410200200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Myeong J. Nam, Mee K. Kee, Rork Kuick, and Samir M. Hanash: Identification of Defensin ${alpha}$ 6 as a Potential Biomarker in Colon Adenocarcinoma
J. Biol. Chem. 2005 280: 8260-8265. First Published on December 21, 2004; doi:10.1074/jbc.M410054200 [Abstract] [Full Text] [PDF]

Protein Structure and Folding:

Ronald R. Bean, Ingrid M. Verhamme, and Paul E. Bock: Role of the Streptokinase ${alpha}$ -Domain in the Interactions of Streptokinase with Plasminogen and Plasmin
J. Biol. Chem. 2005 280: 7504-7510. First Published on December 28, 2004; doi:10.1074/jbc.M411637200 [Abstract] [Full Text] [PDF]

Sayuri Taniguchi, Nobuyuki Suzuki, Masami Masuda, Shin-ichi Hisanaga, Takeshi Iwatsubo, Michel Goedert, and Masato Hasegawa: Inhibition of Heparin-induced Tau Filament Formation by Phenothiazines, Polyphenols, and Porphyrins
J. Biol. Chem. 2005 280: 7614-7623. First Published on December 17, 2004; doi:10.1074/jbc.M408714200 [Abstract] [Full Text] [PDF]

Andrew Lockhart, Liang Ye, Duncan B. Judd, Andy T. Merritt, Peter N. Lowe, Jennifer L. Morgenstern, Guizhu Hong, Antony D. Gee, and John Brown: Evidence for the Presence of Three Distinct Binding Sites for the Thioflavin T Class of Alzheimer's Disease PET Imaging Agents on ${beta}$ -Amyloid Peptide Fibrils
J. Biol. Chem. 2005 280: 7677-7684. First Published on December 21, 2004; doi:10.1074/jbc.M412056200 [Abstract] [Full Text] [PDF]

Eric A. Greenbaum, Charles L. Graves, Amanda J. Mishizen-Eberz, Michael A. Lupoli, David R. Lynch, S. Walter Englander, Paul H. Axelsen, and Benoit I. Giasson: The E46K Mutation in ${alpha}$ -Synuclein Increases Amyloid Fibril Formation
J. Biol. Chem. 2005 280: 7800-7807. First Published on January 4, 2005; doi:10.1074/jbc.M411638200 [Abstract] [Full Text] [PDF]

Yves J. M. Bollen, Sanne M. Nabuurs, Willem J. H. van Berkel, and Carlo P. M. van Mierlo: Last In, First Out: THE ROLE OF COFACTOR BINDING IN FLAVODOXIN FOLDING
J. Biol. Chem. 2005 280: 7836-7844. First Published on January 4, 2005; doi:10.1074/jbc.M412871200 [Abstract] [Full Text] [PDF]

Irene Díaz-Moreno, Antonio Díaz-Quintana, Fernando P. Molina-Heredia, Pedro M. Nieto, Örjan Hansson, Miguel A. De la Rosa, and B. Göran Karlsson: NMR Analysis of the Transient Complex between Membrane Photosystem I and Soluble Cytochrome c₆
J. Biol. Chem. 2005 280: 7925-7931. First Published on December 16, 2004; doi:10.1074/jbc.M412422200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Michael J. Orsini, Irina Nesmelova, Helen C. Young, Balazs Hargittai, Mary Pat Beavers, Jingchun Liu, Peter J. Connolly, Steven A. Middleton, and Kevin H. Mayo: The Nociceptin Pharmacophore Site for Opioid Receptor Binding Derived from the NMR Structure and Bioactivity Relationships
J. Biol. Chem. 2005 280: 8134-8142. First Published on December 13, 2004; doi:10.1074/jbc.M406405200 [Abstract] [Full Text] [PDF]

Kevin W.-H. Lo, Ho-Man Kan, Ling-Nga Chan, Wei-Guang Xu, Ke-Peng Wang, Zhenguo Wu, Morgan Sheng, and Mingjie Zhang: The 8-kDa Dynein Light Chain Binds to p53-binding Protein 1 and Mediates DNA Damage-induced p53 Nuclear Accumulation
J. Biol. Chem. 2005 280: 8172-8179. First Published on December 20, 2004; doi:10.1074/jbc.M411408200 [Abstract] [Full Text] [PDF]

Fabrizio Villa, Maria Deak, Graham B. Bloomberg, Dario R. Alessi, and Daan M. F. van Aalten: Crystal Structure of the PTPL1/FAP-1 Human Tyrosine Phosphatase Mutated in Colorectal Cancer: EVIDENCE FOR A SECOND PHOSPHOTYROSINE SUBSTRATE RECOGNITION POCKET
J. Biol. Chem. 2005 280: 8180-8187. First Published on December 20, 2004; doi:10.1074/jbc.M412211200 [Abstract] [Full Text] [PDF]

István Horváth, Veronika Harmat, András Perczel, Villo Pálfi, László Nyitray, Attila Nagy, Emma Hlavanda, Gábor Náray-Szabó, and Judit Ovádi: The Structure of the Complex of Calmodulin with KAR-2: A NOVEL MODE OF BINDING EXPLAINS THE UNIQUE PHARMACOLOGY OF THE DRUG
J. Biol. Chem. 2005 280: 8266-8274. First Published on December 13, 2004; doi:10.1074/jbc.M410353200 [Abstract] [Full Text] [PDF]

Piotr Jakimowicz, Myles R. Cheesman, William R. Bishai, Keith F. Chater, Andrew J. Thomson, and Mark J. Buttner: Evidence That the Streptomyces Developmental Protein WhiD, a Member of the WhiB Family, Binds a [4Fe-4S] Cluster
J. Biol. Chem. 2005 280: 8309-8315. First Published on December 21, 2004; doi:10.1074/jbc.M412622200 [Abstract] [Full Text] [PDF]

Melanie A. Adams and Zongchao Jia: Structural and Biochemical Evidence for an Enzymatic Quinone Redox Cycle in Escherichia coli: IDENTIFICATION OF A NOVEL QUINOL MONOOXYGENASE
J. Biol. Chem. 2005 280: 8358-8363. First Published on December 21, 2004; doi:10.1074/jbc.M412637200 [Abstract] [Full Text] [PDF] [Supplemental data]

Johannes Haugstetter, Thomas Blicher, and Lars Ellgaard: Identification and Characterization of a Novel Thioredoxin-related Transmembrane Protein of the Endoplasmic Reticulum
J. Biol. Chem. 2005 280: 8371-8380. First Published on December 28, 2004; doi:10.1074/jbc.M413924200 [Abstract] [Full Text] [PDF]

Jose M. de Pereda, Kate L. Wegener, Eugenio Santelli, Neil Bate, Mark H. Ginsberg, David R. Critchley, Iain D. Campbell, and Robert C. Liddington: Structural Basis for Phosphatidylinositol Phosphate Kinase Type I ${gamma}$ Binding to Talin at Focal Adhesions
J. Biol. Chem. 2005 280: 8381-8386. First Published on December 28, 2004; doi:10.1074/jbc.M413180200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Holly R. Gentry, Alex U. Singer, Laurie Betts, Cheng Yang, Joseph D. Ferrara, John Sondek, and Leslie V. Parise: Structural and Biochemical Characterization of CIB1 Delineates a New Family of EF-hand-containing Proteins
J. Biol. Chem. 2005 280: 8407-8415. First Published on December 1, 2004; doi:10.1074/jbc.M411515200 [Abstract] [Full Text] [PDF]

Kate F. Fulton, Ashley M. Buckle, Lisa D. Cabrita, James A. Irving, Rebecca E. Butcher, Ian Smith, Shane Reeve, Arthur M. Lesk, Stephen P. Bottomley, Jamie Rossjohn, and James C. Whisstock: The High Resolution Crystal Structure of a Native Thermostable Serpin Reveals the Complex Mechanism Underpinning the Stressed to Relaxed Transition
J. Biol. Chem. 2005 280: 8435-8442. First Published on December 7, 2004; doi:10.1074/jbc.M410206200 [Abstract] [Full Text] [PDF]

Miklós S. Z. Kellermayer, László Grama, Árpád Karsai, Attila Nagy, Amram Kahn, Zsolt L. Datki, and Botond Penke: Reversible Mechanical Unzipping of Amyloid ${beta}$ -Fibrils
J. Biol. Chem. 2005 280: 8464-8470. First Published on December 13, 2004; doi:10.1074/jbc.M411556200 [Abstract] [Full Text] [PDF]

Yoshihide Osada, Tadafumi Hashimoto, Akiko Nishimura, Yuko Matsuo, Tomoko Wakabayashi, and Takeshi Iwatsubo: CLAC Binds to Amyloid ${beta}$ Peptides through the Positively Charged Amino Acid Cluster within the Collagenous Domain 1 and Inhibits Formation of Amyloid Fibrils
J. Biol. Chem. 2005 280: 8596-8605. First Published on December 21, 2004; doi:10.1074/jbc.M413340200 [Abstract] [Full Text] [PDF]

Enzyme Catalysis and Regulation:

Arturo J. Cardounel, Yong Xia, and Jay L. Zweier: Endogenous Methylarginines Modulate Superoxide as Well as Nitric Oxide Generation from Neuronal Nitric-oxide Synthase: DIFFERENCES IN THE EFFECTS OF MONOMETHYL- AND DIMETHYLARGININES IN THE PRESENCE AND ABSENCE OF TETRAHYDROBIOPTERIN
J. Biol. Chem. 2005 280: 7540-7549. First Published on December 1, 2004; doi:10.1074/jbc.M410241200 [Abstract] [Full Text] [PDF]

Adam A. Golabek, Marius Walus, Krystyna E. Wisniewski, and Elizabeth Kida: Glycosaminoglycans Modulate Activation, Activity, and Stability of Tripeptidyl-peptidase I in Vitro and in Vivo
J. Biol. Chem. 2005 280: 7550-7561. First Published on December 6, 2004; doi:10.1074/jbc.M412047200 [Abstract] [Full Text] [PDF]

Emily E. Jameson, Rebecca A. Roof, Matthew R. Whorton, Henry I. Mosberg, Roger K. Sunahara, Richard R. Neubig, and Robert T. Kennedy: Real-time Detection of Basal and Stimulated G Protein GTPase Activity Using Fluorescent GTP Analogues
J. Biol. Chem. 2005 280: 7712-7719. First Published on December 21, 2004; doi:10.1074/jbc.M413810200 [Abstract] [Full Text] [PDF]

Jason D. Nichols and K. V. Rajagopalan: In Vitro Molybdenum Ligation to Molybdopterin Using Purified Components
J. Biol. Chem. 2005 280: 7817-7822. First Published on January 4, 2005; doi:10.1074/jbc.M413783200 [Abstract] [Full Text] [PDF]

Meihao Sun, John L. Andreassi, II, Shuqing Liu, Rachel Pinto, James A. Triccas, and Thomas S. Leyh: The Trifunctional Sulfate-activating Complex (SAC) of Mycobacterium tuberculosis
J. Biol. Chem. 2005 280: 7861-7866. First Published on December 22, 2004; doi:10.1074/jbc.M409613200 [Abstract] [Full Text] [PDF]

Hong Xu, Leslie A. Bush, Agustin O. Pineda, Sonia Caccia, and Enrico Di Cera: Thrombomodulin Changes the Molecular Surface of Interaction and the Rate of Complex Formation between Thrombin and Protein C
J. Biol. Chem. 2005 280: 7956-7961. First Published on December 6, 2004; doi:10.1074/jbc.M412869200 [Abstract] [Full Text] [PDF]

Pedro Crevillén, Tiziana Ventriglia, Francisco Pinto, Alicia Orea, Ángel Mérida, and José M. Romero: Differential Pattern of Expression and Sugar Regulation of Arabidopsis thaliana ADP-glucose Pyrophosphorylase-encoding Genes
J. Biol. Chem. 2005 280: 8143-8149. First Published on December 14, 2004; doi:10.1074/jbc.M411713200 [Abstract] [Full Text] [PDF]

James D. Swarbrick, Smrithi Buyya, Dilantha Gunawardana, Kenwyn R. Gayler, Alexander G. McLennan, and Paul R. Gooley: Structure and Substrate-binding Mechanism of Human Ap₄A Hydrolase
J. Biol. Chem. 2005 280: 8471-8481. First Published on December 13, 2004; doi:10.1074/jbc.M412318200 [Abstract] [Full Text] [PDF]

Metabolism and Bioenergetics:

Karen E. Christensen, Harshila Patel, Uros Kuzmanov, Narciso R. Mejia, and Robert E. MacKenzie: Disruption of the Mthfd1 Gene Reveals a Monofunctional 10-Formyltetrahydrofolate Synthetase in Mammalian Mitochondria
J. Biol. Chem. 2005 280: 7597-7602. First Published on December 16, 2004; doi:10.1074/jbc.M409380200 [Abstract] [Full Text] [PDF]

Nina Cassanova, Kristin M. O'Brien, Brett T. Stahl, Travis McClure, and Robert O. Poyton: Yeast Flavohemoglobin, a Nitric Oxide Oxidoreductase, Is Located in Both the Cytosol and the Mitochondrial Matrix: EFFECTS OF RESPIRATION, ANOXIA, AND THE MITOCHONDRIAL GENOME ON ITS INTRACELLULAR LEVEL AND DISTRIBUTION
J. Biol. Chem. 2005 280: 7645-7653. First Published on December 20, 2004; doi:10.1074/jbc.M411478200 [Abstract] [Full Text] [PDF]

Paul R. Wheeler, Nicholas G. Coldham, Lisa Keating, Stephen V. Gordon, Esen E. Wooff, Tanya Parish, and R. Glyn Hewinson: Functional Demonstration of Reverse Transsulfuration in the Mycobacterium tuberculosis Complex Reveals That Methionine Is the Preferred Sulfur Source for Pathogenic Mycobacteria
J. Biol. Chem. 2005 280: 8069-8078. First Published on December 2, 2004; doi:10.1074/jbc.M412540200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Glycobiology and Extracellular Matrices:

Kimberly M. Anderson, Hisashi Ashida, Karol Maskos, Anne Dell, Su-Chen Li, and Yu-Teh Li: A Clostridial Endo- ${beta}$ -galactosidase That Cleaves Both Blood Group A and B Glycotopes: THE FIRST MEMBER OF A NEW GLYCOSIDE HYDROLASE FAMILY, GH98
J. Biol. Chem. 2005 280: 7720-7728. First Published on December 22, 2004; doi:10.1074/jbc.M414099200 [Abstract] [Full Text] [PDF]

Renaud Leonard, Bent O. Petersen, Martin Himly, Waltraud Kaar, Nicole Wopfner, Daniel Kolarich, Ronald van Ree, Christof Ebner, Jens Ø. Duus, Fátima Ferreira, and Friedrich Altmann: Two Novel Types of O-Glycans on the Mugwort Pollen Allergen Art v 1 and Their Role in Antibody Binding
J. Biol. Chem. 2005 280: 7932-7940. First Published on December 10, 2004; doi:10.1074/jbc.M410407200 [Abstract] [Full Text] [PDF]

Edith Hintermann, Neng Yang, Deirdre O'Sullivan, Jonathan M. G. Higgins, and Vito Quaranta: Integrin ${alpha}$ 6 ${beta}$ 4-erbB2 Complex Inhibits Haptotaxis by Up-regulating E-cadherin Cell-Cell Junctions in Keratinocytes
J. Biol. Chem. 2005 280: 8004-8015. First Published on December 3, 2004; doi:10.1074/jbc.M406301200 [Abstract] [Full Text] [PDF]

Cristiane G. Lin, Chih-Chiun Chen, Shr-Jeng Leu, Tatiana M. Grzeszkiewicz, and Lester F. Lau: Integrin-dependent Functions of the Angiogenic Inducer NOV (CCN3): IMPLICATION IN WOUND HEALING
J. Biol. Chem. 2005 280: 8229-8237. First Published on December 20, 2004; doi:10.1074/jbc.M404903200 [Abstract] [Full Text] [PDF]

Hong Liao, Wen-yu Bu, Ting-Hua Wang, Sohail Ahmed, and Zhi-Cheng Xiao: Tenascin-R Plays a Role in Neuroprotection via Its Distinct Domains That Coordinate to Modulate the Microglia Function
J. Biol. Chem. 2005 280: 8316-8323. First Published on December 22, 2004; doi:10.1074/jbc.M412730200 [Abstract] [Full Text] [PDF]

Hua-Bei Guo, Intaek Lee, Beau T. Bryan, and Michael Pierce: Deletion of Mouse Embryo Fibroblast N-Acetylglucosaminyltransferase V Stimulates ${alpha}$ 5 ${beta}$ 1 Integrin Expression Mediated by the Protein Kinase C Signaling Pathway
J. Biol. Chem. 2005 280: 8332-8342. First Published on December 22, 2004; doi:10.1074/jbc.M413532200 [Abstract] [Full Text] [PDF]

Shinobu Kitazume, Kazuhiro Nakagawa, Ritsuko Oka, Yuriko Tachida, Kazuko Ogawa, Yi Luo, Martin Citron, Hiroshi Shitara, Choji Taya, Hiromichi Yonekawa, James C. Paulson, Eiji Miyoshi, Naoyuki Taniguchi, and Yasuhiro Hashimoto: In Vivo Cleavage of ${alpha}$ 2,6-Sialyltransferase by Alzheimer ${beta}$ -Secretase
J. Biol. Chem. 2005 280: 8589-8595. First Published on September 13, 2004; doi:10.1074/jbc.M409417200 [Abstract] [Full Text] [PDF]

Lipids and Lipoproteins:

Yuki Nakamura, Koichiro Awai, Tatsuru Masuda, Yasushi Yoshioka, Ken-ichiro Takamiya, and Hiroyuki Ohta: A Novel Phosphatidylcholine-hydrolyzing Phospholipase C Induced by Phosphate Starvation in Arabidopsis
J. Biol. Chem. 2005 280: 7469-7476. First Published on December 23, 2004; doi:10.1074/jbc.M408799200 [Abstract] [Full Text] [PDF]

Toralf Senger, Thomas Wichard, Susan Kunze, Cornelia Göbel, Jens Lerchl, Georg Pohnert, and Ivo Feussner: A Multifunctional Lipoxygenase with Fatty Acid Hydroperoxide Cleaving Activity from the Moss Physcomitrella patens
J. Biol. Chem. 2005 280: 7588-7596. First Published on December 15, 2004; doi:10.1074/jbc.M411738200 [Abstract] [Full Text] [PDF]

Fernando Sánchez-Barbero, Jochen Strassner, Rafael García-Cañero, Wolfram Steinhilber, and Cristina Casals: Role of the Degree of Oligomerization in the Structure and Function of Human Surfactant Protein A
J. Biol. Chem. 2005 280: 7659-7670. First Published on December 21, 2004; doi:10.1074/jbc.M410266200 [Abstract] [Full Text] [PDF]

Cécile Voisset, Nathalie Callens, Emmanuelle Blanchard, Anne Op De Beeck, Jean Dubuisson, and Ngoc Vu-Dac: High Density Lipoproteins Facilitate Hepatitis C Virus Entry through the Scavenger Receptor Class B Type I
J. Biol. Chem. 2005 280: 7793-7799. First Published on January 4, 2005; doi:10.1074/jbc.M411600200 [Abstract] [Full Text] [PDF]

Irina N. Baranova, Tatyana G. Vishnyakova, Alexander V. Bocharov, Roger Kurlander, Zhigang Chen, Michael L. Kimelman, Alan T. Remaley, Gyorgy Csako, Fairwell Thomas, Thomas L. Eggerman, and Amy P. Patterson: Serum Amyloid A Binding to CLA-1 (CD36 and LIMPII Analogous-1) Mediates Serum Amyloid A Protein-induced Activation of ERK1/2 and p38 Mitogen-activated Protein Kinases
J. Biol. Chem. 2005 280: 8031-8040. First Published on December 2, 2004; doi:10.1074/jbc.M405009200 [Abstract] [Full Text] [PDF]

Jeroen Geurtsen, Liana Steeghs, Jan ten Hove, Peter van der Ley, and Jan Tommassen: Dissemination of Lipid A Deacylases (PagL) among Gram-negative Bacteria: IDENTIFICATION OF ACTIVE-SITE HISTIDINE AND SERINE RESIDUES
J. Biol. Chem. 2005 280: 8248-8259. First Published on December 20, 2004; doi:10.1074/jbc.M414235200 [Abstract] [Full Text] [PDF]

Membrane Transport, Structure, Function, and Biogenesis:

Jeremy J. Rose, Katy Janvier, Soundararajulu Chandrasekhar, Rafick P. Sekaly, Juan S. Bonifacino, and Sundararajan Venkatesan: CD4 Down-regulation by HIV-1 and Simian Immunodeficiency Virus (SIV) Nef Proteins Involves Both Internalization and Intracellular Retention Mechanisms
J. Biol. Chem. 2005 280: 7413-7426. First Published on December 16, 2004; doi:10.1074/jbc.M409420200 [Abstract] [Full Text] [PDF]

Agnes K. Nagy, David J. Kane, Chinh M. Tran, Robert A. Farley, and Larry D. Faller: Evidence Calcium Pump Binds Magnesium before Inorganic Phosphate
J. Biol. Chem. 2005 280: 7435-7443. First Published on December 10, 2004; doi:10.1074/jbc.M412319200 [Abstract] [Full Text] [PDF]

Adam B. Weinglass, Misha Soskine, Jose-Luis Vazquez-Ibar, Julian P. Whitelegge, Kym F. Faull, H. Ronald Kaback, and Shimon Schuldiner: Exploring the Role of a Unique Carboxyl Residue in EmrE by Mass Spectrometry
J. Biol. Chem. 2005 280: 7487-7492. First Published on December 28, 2004; doi:10.1074/jbc.M413555200 [Abstract] [Full Text] [PDF]

Sumie Manno, Yuichi Takakuwa, and Narla Mohandas: Modulation of Erythrocyte Membrane Mechanical Function by Protein 4.1 Phosphorylation
J. Biol. Chem. 2005 280: 7581-7587. First Published on December 15, 2004; doi:10.1074/jbc.M410650200 [Abstract] [Full Text] [PDF]

Stephan Kellenberger, Ivan Gautschi, Yvan Pfister, and Laurent Schild: Intracellular Thiol-mediated Modulation of Epithelial Sodium Channel Activity
J. Biol. Chem. 2005 280: 7739-7747. First Published on December 28, 2004; doi:10.1074/jbc.M409955200 [Abstract] [Full Text] [PDF]

Jinoh Kim, Susan Hamamoto, Mariella Ravazzola, Lelio Orci, and Randy Schekman: Uncoupled Packaging of Amyloid Precursor Protein and Presenilin 1 into Coat Protein Complex II Vesicles
J. Biol. Chem. 2005 280: 7758-7768. First Published on December 28, 2004; doi:10.1074/jbc.M411091200 [Abstract] [Full Text] [PDF]

Stephan Meier, Walter Neupert, and Johannes M. Herrmann: Conserved N-terminal Negative Charges in the Tim17 Subunit of the TIM23 Translocase Play a Critical Role in the Import of Preproteins into Mitochondria
J. Biol. Chem. 2005 280: 7777-7785. First Published on December 23, 2004; doi:10.1074/jbc.M412158200 [Abstract] [Full Text] [PDF]

Claude Lopez, Sylvain Métral, Dominique Eladari, Stéphanie Drevensek, Pierre Gane, Régine Chambrey, Vann Bennett, Jean-Pierre Cartron, Caroline Le Van Kim, and Yves Colin: The Ammonium Transporter RhBG: REQUIREMENT OF A TYROSINE-BASED SIGNAL AND ANKYRIN-G FOR BASOLATERAL TARGETING AND MEMBRANE ANCHORAGE IN POLARIZED KIDNEY EPITHELIAL CELLS
J. Biol. Chem. 2005 280: 8221-8228. First Published on December 17, 2004; doi:10.1074/jbc.M413351200 [Abstract] [Full Text] [PDF]

Keita Imai, Yoichi Noda, Hiroyuki Adachi, and Koji Yoda: A Novel Endoplasmic Reticulum Membrane Protein Rcr1 Regulates Chitin Deposition in the Cell Wall of Saccharomyces cerevisiae
J. Biol. Chem. 2005 280: 8275-8284. First Published on December 8, 2004; doi:10.1074/jbc.M409428200 [Abstract] [Full Text] [PDF]

Fan Gao, Nina Bren, Thomas P. Burghardt, Scott Hansen, Richard H. Henchman, Palmer Taylor, J. Andrew McCammon, and Steven M. Sine: Agonist-mediated Conformational Changes in Acetylcholine-binding Protein Revealed by Simulation and Intrinsic Tryptophan Fluorescence
J. Biol. Chem. 2005 280: 8443-8451. First Published on December 9, 2004; doi:10.1074/jbc.M412389200 [Abstract] [Full Text] [PDF]

Valérie Beaulieu, Nicolas Da Silva, Nuria Pastor-Soler, Christopher R. Brown, Peter J. S. Smith, Dennis Brown, and Sylvie Breton: Modulation of the Actin Cytoskeleton via Gelsolin Regulates Vacuolar H⁺-ATPase Recycling
J. Biol. Chem. 2005 280: 8452-8463. First Published on December 9, 2004; doi:10.1074/jbc.M412750200 [Abstract] [Full Text] [PDF]

Shaohu Sheng, Clint J. Perry, Ossama B. Kashlan, and Thomas R. Kleyman: Side Chain Orientation of Residues Lining the Selectivity Filter of Epithelial Na⁺ Channels
J. Biol. Chem. 2005 280: 8513-8522. First Published on December 20, 2004; doi:10.1074/jbc.M413880200 [Abstract] [Full Text] [PDF]

J. Pedro Fernández Murray and Christopher R. McMaster: Nte1p-mediated Deacylation of Phosphatidylcholine Functionally Interacts with Sec14p
J. Biol. Chem. 2005 280: 8544-8552. First Published on December 20, 2004; doi:10.1074/jbc.M413999200 [Abstract] [Full Text] [PDF]

Marina N. Chernova, Lianwei Jiang, David J. Friedman, Rachel B. Darman, Hannes Lohi, Juha Kere, David H. Vandorpe, and Seth L. Alper: Functional Comparison of Mouse slc26a6 Anion Exchanger with Human SLC26A6 Polypeptide Variants: DIFFERENCES IN ANION SELECTIVITY, REGULATION, AND ELECTROGENICITY
J. Biol. Chem. 2005 280: 8564-8580. First Published on November 17, 2004; doi:10.1074/jbc.M411703200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Mechanisms Of Signal Transduction:

Carolyn M. Klinge, Kristy A. Blankenship, Kelly E. Risinger, Shephali Bhatnagar, Edouard L. Noisin, Wasana K. Sumanasekera, Lei Zhao, Darren M. Brey, and Robert S. Keynton: Resveratrol and Estradiol Rapidly Activate MAPK Signaling through Estrogen Receptors ${alpha}$ and ${beta}$ in Endothelial Cells
J. Biol. Chem. 2005 280: 7460-7468. First Published on December 22, 2004; doi:10.1074/jbc.M411565200 [Abstract] [Full Text] [PDF]

Simon-Pierre Gravel and Marc J. Servant: Roles of an I ${kappa}$ B Kinase-related Pathway in Human Cytomegalovirus-infected Vascular Smooth Muscle Cells: A MOLECULAR LINK IN PATHOGEN-INDUCED PROATHEROSCLEROTIC CONDITIONS
J. Biol. Chem. 2005 280: 7477-7486. First Published on December 24, 2004; doi:10.1074/jbc.M410392200 [Abstract] [Full Text] [PDF]

Takashi Yasukawa, Eriko Tokunaga, Hidetaka Ota, Hiroki Sugita, J. A. Jeevendra Martyn, and Masao Kaneki: S-Nitrosylation-dependent Inactivation of Akt/Protein Kinase B in Insulin Resistance
J. Biol. Chem. 2005 280: 7511-7518. First Published on January 4, 2005; doi:10.1074/jbc.M411871200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Barry B. Rubin, Gregory P. Downey, Adeline Koh, Norbert Degousee, Farideh Ghomashchi, Laxman Nallan, Eva Stefanski, Denis W. Harkin, ChunXiang Sun, Brian P. Smart, Thomas F. Lindsay, Vera Cherepanov, Eric Vachon, David Kelvin, Martin Sadilek, Glenn E. Brown, Michael B. Yaffe, Jonathan Plumb, Sergio Grinstein, Michael Glogauer, and Michael H. Gelb: Cytosolic Phospholipase A₂- ${alpha}$ Is Necessary for Platelet-activating Factor Biosynthesis, Efficient Neutrophil-mediated Bacterial Killing, and the Innate Immune Response to Pulmonary Infection: cPLA₂- ${alpha}$ DOES NOT REGULATE NEUTROPHIL NADPH OXIDASE ACTIVITY
J. Biol. Chem. 2005 280: 7519-7529. First Published on October 8, 2004; doi:10.1074/jbc.M407438200 [Abstract] [Full Text] [PDF]

Huajun Qin, Heather S. Carr, Xiaochong Wu, Daniella Muallem, Nancy H. Tran, and Jeffrey A. Frost: Characterization of the Biochemical and Transforming Properties of the Neuroepithelial Transforming Protein 1
J. Biol. Chem. 2005 280: 7603-7613. First Published on December 16, 2004; doi:10.1074/jbc.M412141200 [Abstract] [Full Text] [PDF]

Patrick A. Kiely, Madeline Leahy, Denise O'Gorman, and Rosemary O'Connor: RACK1-mediated Integration of Adhesion and Insulin-like Growth Factor I (IGF-I) Signaling and Cell Migration Are Defective in Cells Expressing an IGF-I Receptor Mutated at Tyrosines 1250 and 1251
J. Biol. Chem. 2005 280: 7624-7633. First Published on December 17, 2004; doi:10.1074/jbc.M412889200 [Abstract] [Full Text] [PDF]

Ling-Chi Wang, Cindy Yen Okitsu, and Ebrahim Zandi: Tumor Necrosis Factor ${alpha}$ -dependent Drug Resistance to Purine and Pyrimidine Analogues in Human Colon Tumor Cells Mediated through IKK
J. Biol. Chem. 2005 280: 7634-7644. First Published on December 17, 2004; doi:10.1074/jbc.M413384200 [Abstract] [Full Text] [PDF]

Samson Amos, Patrick M. Martin, Gregory A. Polar, Sarah J. Parsons, and Isa M. Hussaini: Phorbol 12-Myristate 13-Acetate Induces Epidermal Growth Factor Receptor Transactivation via Protein Kinase C ${delta}$ /c-Src Pathways in Glioblastoma Cells
J. Biol. Chem. 2005 280: 7729-7738. First Published on December 23, 2004; doi:10.1074/jbc.M409056200 [Abstract] [Full Text] [PDF]

Jen-Hsuan Wei, Yi-Fan Chou, Yi-Hung Ou, Yen-Hsiu Yeh, Shiaw-Wei Tyan, Te-Ping Sun, Chen-Yang Shen, and Sheau-Yann Shieh: TTK/hMps1 Participates in the Regulation of DNA Damage Checkpoint Response by Phosphorylating CHK2 on Threonine 68
J. Biol. Chem. 2005 280: 7748-7757. First Published on December 23, 2004; doi:10.1074/jbc.M410152200 [Abstract] [Full Text] [PDF]

Scot A. Lieser, Caitlin Shindler, Brandon E. Aubol, Sungsoo Lee, Gongqin Sun, and Joseph A. Adams: Phosphoryl Transfer Step in the C-terminal Src Kinase Controls Src Recognition
J. Biol. Chem. 2005 280: 7769-7776. First Published on December 28, 2004; doi:10.1074/jbc.M411736200 [Abstract] [Full Text] [PDF]

Nicolas Audet, Mélanie Paquin-Gobeil, Olivier Landry-Paquet, Peter W. Schiller, and Graciela Piñeyro: Internalization and Src Activity Regulate the Time Course of ERK Activation by Delta Opioid Receptor Ligands
J. Biol. Chem. 2005 280: 7808-7816. First Published on January 4, 2005; doi:10.1074/jbc.M411695200 [Abstract] [Full Text] [PDF]

Eun Ok Lee, Jihee Lee Kang, and Young Hae Chong: The Amyloid- ${beta}$ Peptide Suppresses Transforming Growth Factor- ${beta}$ 1-induced Matrix Metalloproteinase-2 Production via Smad7 Expression in Human Monocytic THP-1 Cells
J. Biol. Chem. 2005 280: 7845-7853. First Published on January 4, 2005; doi:10.1074/jbc.M409101200 [Abstract] [Full Text] [PDF]

Jane A. Gwira, Feng Wei, Shuta Ishibe, Joseph M. Ueland, Jonathan Barasch, and Lloyd G. Cantley: Expression of Neutrophil Gelatinase-associated Lipocalin Regulates Epithelial Morphogenesis in Vitro
J. Biol. Chem. 2005 280: 7875-7882. First Published on January 6, 2005; doi:10.1074/jbc.M413192200 [Abstract] [Full Text] [PDF]

Diego Sbrissa and Assia Shisheva: Acquisition of Unprecedented Phosphatidylinositol 3,5-Bisphosphate Rise in Hyperosmotically Stressed 3T3-L1 Adipocytes, Mediated by ArPIKfyve-PIKfyve Pathway
J. Biol. Chem. 2005 280: 7883-7889. First Published on November 16, 2004; doi:10.1074/jbc.M412729200 [Abstract] [Full Text] [PDF]

Guru Dutt Sharma, Paulo Ottino, Nicolas G. Bazan, and Haydee E. P. Bazan: Epidermal and Hepatocyte Growth Factors, but Not Keratinocyte Growth Factor, Modulate Protein Kinase C ${alpha}$ Translocation to the Plasma Membrane through 15(S)-Hydroxyeicosatetraenoic Acid Synthesis
J. Biol. Chem. 2005 280: 7917-7924. First Published on December 21, 2004; doi:10.1074/jbc.M408852200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Guido T. Bommer, Claudia Jäger, Eva-Maria Dürr, Sebastian Baehs, Sören T. Eichhorst, Thomas Brabletz, Gang Hu, Thomas Fröhlich, Georg Arnold, Dagmar C. Kress, Burkhard Göke, Eric R. Fearon, and Frank T. Kolligs: DRO1, a Gene Down-regulated by Oncogenes, Mediates Growth Inhibition in Colon and Pancreatic Cancer Cells
J. Biol. Chem. 2005 280: 7962-7975. First Published on November 24, 2004; doi:10.1074/jbc.M412593200 [Abstract] [Full Text] [PDF]

Anthony P. Barnes, Gabriel Livera, Pingbo Huang, Chuanwen Sun, Wanda K. O'Neal, Marco Conti, M. Jackson Stutts, and Sharon L. Milgram: Phosphodiesterase 4D Forms a cAMP Diffusion Barrier at the Apical Membrane of the Airway Epithelium
J. Biol. Chem. 2005 280: 7997-8003. First Published on December 15, 2004; doi:10.1074/jbc.M407521200 [Abstract] [Full Text] [PDF]

Hang Yin, Lee Chao, and Julie Chao: Kallikrein/Kinin Protects against Myocardial Apoptosis after Ischemia/Reperfusion via Akt-Glycogen Synthase Kinase-3 and Akt-Bad·14-3-3 Signaling Pathways
J. Biol. Chem. 2005 280: 8022-8030. First Published on December 20, 2004; doi:10.1074/jbc.M407179200 [Abstract] [Full Text] [PDF]

William G. Barnes, Eric Reiter, Jonathan D. Violin, Xiu-Rong Ren, Graeme Milligan, and Robert J. Lefkowitz: ${beta}$ -Arrestin 1 and G_q/11 Coordinately Activate RhoA and Stress Fiber Formation following Receptor Stimulation
J. Biol. Chem. 2005 280: 8041-8050. First Published on December 16, 2004; doi:10.1074/jbc.M412924200 [Abstract] [Full Text] [PDF]

Taihao Quan, Tianyuan He, John J. Voorhees, and Gary J. Fisher: Ultraviolet Irradiation Induces Smad7 via Induction of Transcription Factor AP-1 in Human Skin Fibroblasts
J. Biol. Chem. 2005 280: 8079-8085. First Published on December 3, 2004; doi:10.1074/jbc.M409647200 [Abstract] [Full Text] [PDF]

Miren Kerkmann, Lilian T. Costa, Christine Richter, Simon Rothenfusser, Julia Battiany, Veit Hornung, Judith Johnson, Steffen Englert, Thomas Ketterer, Wolfgang Heckl, Stefan Thalhammer, Stefan Endres, and Gunther Hartmann: Spontaneous Formation of Nucleic Acid-based Nanoparticles Is Responsible for High Interferon- ${alpha}$ Induction by CpG-A in Plasmacytoid Dendritic Cells
J. Biol. Chem. 2005 280: 8086-8093. First Published on December 8, 2004; doi:10.1074/jbc.M410868200 [Abstract] [Full Text] [PDF]

Qun Zhao, Edward G. Shepherd, Mary E. Manson, Leif D. Nelin, Andrey Sorokin, and Yusen Liu: The Role of Mitogen-activated Protein Kinase Phosphatase-1 in the Response of Alveolar Macrophages to Lipopolysaccharide: ATTENUATION OF PROINFLAMMATORY CYTOKINE BIOSYNTHESIS VIA FEEDBACK CONTROL OF p38
J. Biol. Chem. 2005 280: 8101-8108. First Published on December 8, 2004; doi:10.1074/jbc.M411760200 [Abstract] [Full Text] [PDF]

Mona Gupta and Stephen J. Yarwood: MAP1A Light Chain 2 Interacts with Exchange Protein Activated by Cyclic AMP 1 (EPAC1) to Enhance Rap1 GTPase Activity and Cell Adhesion
J. Biol. Chem. 2005 280: 8109-8116. First Published on December 9, 2004; doi:10.1074/jbc.M413697200 [Abstract] [Full Text] [PDF]

Hee-Jung Kim, Eun Joo Song, Yun-Suk Lee, Eunhee Kim, and Kong-Joo Lee: Human Fas-associated Factor 1 Interacts with Heat Shock Protein 70 and Negatively Regulates Chaperone Activity
J. Biol. Chem. 2005 280: 8125-8133. First Published on December 13, 2004; doi:10.1074/jbc.M406297200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Derek C. Braun, Susan H. Garfield, and Peter M. Blumberg: Analysis by Fluorescence Resonance Energy Transfer of the Interaction between Ligands and Protein Kinase C ${delta}$ in the Intact Cell
J. Biol. Chem. 2005 280: 8164-8171. First Published on December 16, 2004; doi:10.1074/jbc.M413896200 [Abstract] [Full Text] [PDF]

Yuichi Sekine, Tetsuya Yamamoto, Taro Yumioka, Kenji Sugiyama, Satoshi Tsuji, Kenji Oritani, Kazuya Shimoda, Mayu Minoguchi, Akihiko Yoshimura, and Tadashi Matsuda: Physical and Functional Interactions between STAP-2/BKS and STAT5
J. Biol. Chem. 2005 280: 8188-8196. First Published on December 17, 2004; doi:10.1074/jbc.M411692200 [Abstract] [Full Text] [PDF]

Lee Ann Cohen and Jun-Lin Guan: Residues within the First Subdomain of the FERM-like Domain in Focal Adhesion Kinase Are Important in Its Regulation
J. Biol. Chem. 2005 280: 8197-8207. First Published on December 20, 2004; doi:10.1074/jbc.M412021200 [Abstract] [Full Text] [PDF]

Hannah Murdoch, Gui-Jie Feng, Dietmar Bächner, Laura Ormiston, Julia H. White, Dietmar Richter, and Graeme Milligan: Periplakin Interferes with G Protein Activation by the Melanin-concentrating Hormone Receptor-1 by Binding to the Proximal Segment of the Receptor C-terminal Tail
J. Biol. Chem. 2005 280: 8208-8220. First Published on December 6, 2004; doi:10.1074/jbc.M405215200 [Abstract] [Full Text] [PDF]

Kian Kani, Carmen M. Warren, Catherine S. Kaddis, Joseph A. Loo, and Ralf Landgraf: Oligomers of ERBB3 Have Two Distinct Interfaces That Differ in Their Sensitivity to Disruption by Heregulin
J. Biol. Chem. 2005 280: 8238-8247. First Published on December 20, 2004; doi:10.1074/jbc.M410944200 [Abstract] [Full Text] [PDF]

Constance E. Runyan, H. William Schnaper, and Anne-Christine Poncelet: The Role of Internalization in Transforming Growth Factor ${beta}$ 1-induced Smad2 Association with Smad Anchor for Receptor Activation (SARA) and Smad2-dependent Signaling in Human Mesangial Cells
J. Biol. Chem. 2005 280: 8300-8308. First Published on December 21, 2004; doi:10.1074/jbc.M407939200 [Abstract] [Full Text] [PDF]

Jing Li, Kathleen L. O'Connor, George H. Greeley, Jr., Perry J. Blackshear, Courtney M. Townsend, Jr., and B. Mark Evers: Myristoylated Alanine-rich C Kinase Substrate-mediated Neurotensin Release via Protein Kinase C- ${delta}$ Downstream of the Rho/ROK Pathway
J. Biol. Chem. 2005 280: 8351-8357. First Published on December 28, 2004; doi:10.1074/jbc.M409431200 [Abstract] [Full Text] [PDF]

Ronnie Gonen, Dvora Beach, Carmit Ainey, and Deborah Yablonski: T Cell Receptor-induced Activation of Phospholipase C- ${gamma}$ 1 Depends on a Sequence-independent Function of the P-I Region of SLP-76
J. Biol. Chem. 2005 280: 8364-8370. First Published on December 28, 2004; doi:10.1074/jbc.M409437200 [Abstract] [Full Text] [PDF]

Qin Wang, Gregory P. Downey, Maria Teresa Herrera-Abreu, András Kapus, and Christopher A. McCulloch: SHP-2 Modulates Interleukin-1-induced Ca²⁺ Flux and ERK Activation via Phosphorylation of Phospholipase C ${gamma}$ 1
J. Biol. Chem. 2005 280: 8397-8406. First Published on November 24, 2004; doi:10.1074/jbc.M410462200 [Abstract] [Full Text] [PDF]

Ruiyu Xie, Meibao Zhuang, Linda S. Ross, Isabel Gomez, Daniela I. Oltean, Alejandra Bravo, Mario Soberon, and Sarjeet S. Gill: Single Amino Acid Mutations in the Cadherin Receptor from Heliothis virescens Affect Its Toxin Binding Ability to Cry1A Toxins
J. Biol. Chem. 2005 280: 8416-8425. First Published on November 30, 2004; doi:10.1074/jbc.M408403200 [Abstract] [Full Text] [PDF]

Ilia Voskoboinik, Marie-Claude Thia, Jamie Fletcher, Annette Ciccone, Kylie Browne, Mark J. Smyth, and Joseph A. Trapani: Calcium-dependent Plasma Membrane Binding and Cell Lysis by Perforin Are Mediated through Its C2 Domain: A CRITICAL ROLE FOR ASPARTATE RESIDUES 429, 435, 483, AND 485 BUT NOT 491
J. Biol. Chem. 2005 280: 8426-8434. First Published on December 2, 2004; doi:10.1074/jbc.M413303200 [Abstract] [Full Text] [PDF]

Bose S. Kochupurakkal, Daniel Harari, Ayelet Di-Segni, Galia Maik-Rachline, Ljuba Lyass, Gal Gur, Gabriele Kerber, Ami Citri, Sara Lavi, Raya Eilam, Vered Chalifa-Caspi, Zelig Eshhar, Eli Pikarsky, Ronit Pinkas-Kramarski, Sarah S. Bacus, and Yosef Yarden: Epigen, the Last Ligand of ErbB Receptors, Reveals Intricate Relationships between Affinity and Mitogenicity
J. Biol. Chem. 2005 280: 8503-8512. First Published on December 17, 2004; doi:10.1074/jbc.M413919200 [Abstract] [Full Text] [PDF]

Arthur M. Edelman, Woo-Yang Kim, Dennis Higgins, Elaine G. Goldstein, Michele Oberdoerster, and Wade Sigurdson: Doublecortin Kinase-2, a Novel Doublecortin-related Protein Kinase Associated with Terminal Segments of Axons and Dendrites
J. Biol. Chem. 2005 280: 8531-8543. First Published on December 20, 2004; doi:10.1074/jbc.M411027200 [Abstract] [Full Text] [PDF]

Palakurthy Rajendra Kumar, Prabhat K. Singhal, Malireddi R. K. Subba Rao, and Sundarasamy Mahalingam: Phosphorylation by MAPK Regulates Simian Immunodeficiency Virus Vpx Protein Nuclear Import and Virus Infectivity
J. Biol. Chem. 2005 280: 8553-8563. First Published on November 19, 2004; doi:10.1074/jbc.M407863200 [Abstract] [Full Text] [PDF]

Gowdahalli Krishnegowda, Adeline M. Hajjar, Jianzhong Zhu, Erika J. Douglass, Satoshi Uematsu, Shizuo Akira, Amina S. Woods, and D. Channe Gowda: Induction of Proinflammatory Responses in Macrophages by the Glycosylphosphatidylinositols of Plasmodium falciparum: CELL SIGNALING RECEPTORS, GLYCOSYLPHOSPHATIDYLINOSITOL (GPI) STRUCTURAL REQUIREMENT, AND REGULATION OF GPI ACTIVITY
J. Biol. Chem. 2005 280: 8606-8616. First Published on December 28, 2004; doi:10.1074/jbc.M413541200 [Abstract] [Full Text] [PDF]

Jianzhong Zhu, Gowdahalli Krishnegowda, and D. Channe Gowda: Induction of Proinflammatory Responses in Macrophages by the Glycosylphosphatidylinositols of Plasmodium falciparum: THE REQUIREMENT OF EXTRACELLULAR SIGNAL-REGULATED KINASE, p38, c-Jun N-TERMINAL KINASE AND NF- ${kappa}$ B PATHWAYS FOR THE EXPRESSION OF PROINFLAMMATORY CYTOKINES AND NITRIC OXIDE
J. Biol. Chem. 2005 280: 8617-8627. First Published on December 15, 2004; doi:10.1074/jbc.M413539200 [Abstract] [Full Text] [PDF]

Molecular Basis Of Cell and Developmental Biology:

Masaiwa Motoyama, Soh Yamazaki, Akiko Eto-Kimura, Koichiro Takeshige, and Tatsushi Muta: Positive and Negative Regulation of Nuclear Factor- ${kappa}$ B-mediated Transcription by I ${kappa}$ B- ${zeta}$ , an Inducible Nuclear Protein
J. Biol. Chem. 2005 280: 7444-7451. First Published on December 23, 2004; doi:10.1074/jbc.M412738200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Li-Ren Liu, Zhan-Wen Du, Hua-Lu Zhao, Xiao-Ling Liu, Xiao-Dong Huang, Jie Shen, Li-Mei Ju, Fu-De Fang, and Jun-Wu Zhang: T to C Substitution at –175 or –173 of the ${gamma}$ -Globin Promoter Affects GATA-1 and Oct-1 Binding in Vitro Differently but Can Independently Reproduce the Hereditary Persistence of Fetal Hemoglobin Phenotype in Transgenic Mice
J. Biol. Chem. 2005 280: 7452-7459. First Published on December 21, 2004; doi:10.1074/jbc.M411407200 [Abstract] [Full Text] [PDF]

Spiros Vlahopoulos, Warren E. Zimmer, Guido Jenster, Narasimhaswamy S. Belaguli, Steven P. Balk, Albert O. Brinkmann, Rainer B. Lanz, Vassilis C. Zoumpourlis, and Robert J. Schwartz: Recruitment of the Androgen Receptor via Serum Response Factor Facilitates Expression of a Myogenic Gene
J. Biol. Chem. 2005 280: 7786-7792. First Published on December 28, 2004; doi:10.1074/jbc.M413992200 [Abstract] [Full Text] [PDF]

Kristina A. White, Mark M. Yore, Dexin Deng, and Michael J. Spinella: Limiting Effects of RIP140 in Estrogen Signaling: POTENTIAL MEDIATION OF ANTI-ESTROGENIC EFFECTS OF RETINOIC ACID
J. Biol. Chem. 2005 280: 7829-7835. First Published on January 4, 2005; doi:10.1074/jbc.M412707200 [Abstract] [Full Text] [PDF]

Perla Kaliman, Daniele Catalucci, Jason T. Lam, Richard Kondo, José Carlos Paz Gutiérrez, Sita Reddy, Manuel Palacín, Antonio Zorzano, Kenneth R. Chien, and Pilar Ruiz-Lozano: Myotonic Dystrophy Protein Kinase Phosphorylates Phospholamban and Regulates Calcium Uptake in Cardiomyocyte Sarcoplasmic Reticulum
J. Biol. Chem. 2005 280: 8016-8021. First Published on December 13, 2004; doi:10.1074/jbc.M412845200 [Abstract] [Full Text] [PDF]

Michael Zeisberg, Amish A. Shah, and Raghu Kalluri: Bone Morphogenic Protein-7 Induces Mesenchymal to Epithelial Transition in Adult Renal Fibroblasts and Facilitates Regeneration of Injured Kidney
J. Biol. Chem. 2005 280: 8094-8100. First Published on December 9, 2004; doi:10.1074/jbc.M413102200 [Abstract] [Full Text] [PDF]

John R. Harrison, Yu-Feng Huang, K. Amanda Wilson, Penny L. Kelly, Douglas J. Adams, Gloria A. Gronowicz, and Stephen H. Clark: Col1a1 Promoter-targeted Expression of p20 CCAAT Enhancer-binding Protein ${beta}$ (C/EBP ${beta}$ ), a Truncated C/EBP ${beta}$ Isoform, Causes Osteopenia in Transgenic Mice
J. Biol. Chem. 2005 280: 8117-8124. First Published on December 14, 2004; doi:10.1074/jbc.M410076200 [Abstract] [Full Text] [PDF]

Driss Ehirchiou, Yu-Mei Xiong, Yang Li, Shelesa Brew, and Li Zhang: Dual Function for a Unique Site within the ${beta}$ ₂I Domain of Integrin ${alpha}$ _M ${beta}$ ₂
J. Biol. Chem. 2005 280: 8324-8331. First Published on December 22, 2004; doi:10.1074/jbc.M413525200 [Abstract] [Full Text] [PDF]

Takayuki Furumatsu, Masanao Tsuda, Noboru Taniguchi, Yoshitaka Tajima, and Hiroshi Asahara: Smad3 Induces Chondrogenesis through the Activation of SOX9 via CREB-binding Protein/p300 Recruitment
J. Biol. Chem. 2005 280: 8343-8350. First Published on December 28, 2004; doi:10.1074/jbc.M413913200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Andreas Lux, Christian Beil, Meher Majety, Suzanne Barron, Carol J. Gallione, Hella-Monika Kuhn, Jonathan N. Berg, Petra Kioschis, Douglas A. Marchuk, and Mathias Hafner: Human Retroviral gag- and gag-pol-like Proteins Interact with the Transforming Growth Factor- ${beta}$ Receptor Activin Receptor-like Kinase 1
J. Biol. Chem. 2005 280: 8482-8493. First Published on December 16, 2004; doi:10.1074/jbc.M409197200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Sugata Ray, Chun Gao, Keith Wyatt, Robert N. Fariss, Amanda Bundek, Peggy Zelenka, and Graeme Wistow: Platelet-derived Growth Factor D, Tissue-specific Expression in the Eye, and a Key Role in Control of Lens Epithelial Cell Proliferation
J. Biol. Chem. 2005 280: 8494-8502. First Published on December 16, 2004; doi:10.1074/jbc.M413570200 [Abstract] [Full Text] [PDF]

Ryuji Ikeda, Kenichi Yoshida, So Tsukahara, Yoshiko Sakamoto, Hiroshi Tanaka, Ken-Ichi Furukawa, and Ituro Inoue: The Promyelotic Leukemia Zinc Finger Promotes Osteoblastic Differentiation of Human Mesenchymal Stem Cells as an Upstream Regulator of CBFA1
J. Biol. Chem. 2005 280: 8523-8530. First Published on December 28, 2004; doi:10.1074/jbc.M409442200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Additions and Corrections:

Yuko Kawakami, Hajime Nishimoto, Jiro Kitaura, Mari Maeda-Yamamoto, Roberta M. Kato, Dan R. Littman, Michael Leitges, David J. Rawlings, and Toshiaki Kawakami: Protein kinase C ${beta}$ II regulates Akt phosphorylation on Ser-473 in a cell type- and stimulus-specific fashion. Vol. 279 (2004) 47720-47725
J. Biol. Chem. 2005 280: 8628. [Full Text] [PDF]

Valérie Heurgué-Hamard, Stéphanie Champ, Liliana Mora, Tatiana Merkulova-Rainon, Lev L. Kisselev, and Richard H. Buckingham: The glutamine residue of the conserved GGQ motif in Saccharomyces cerevisiae release factor eRF1 is methylated by the product of the YDR140w gene. Vol. 280 (2005) 2439-2445
J. Biol. Chem. 2005 280: 8628-a. [Full Text] [PDF]