JBC -- Table of Contents (Mar 17 2006, 281, (11))

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Reflections:

Howard K. Schachman: From "Publish or Perish" to "Patent and Prosper"
J. Biol. Chem. 2006 281: 6889-6903. First Published ; doi:10.1074/JBC.X600002200 [Full Text] [PDF]

DNA: Replication, Repair, and Recombination:

Gemma Serrano-Heras, Margarita Salas, and Alicia Bravo: A Uracil-DNA Glycosylase Inhibitor Encoded by a Non-uracil Containing Viral DNA
J. Biol. Chem. 2006 281: 7068-7074. First Published on January 18, 2006; doi:10.1074/jbc.M511152200 [Abstract] [Full Text] [PDF]

Monica E. Hamburgh, Kenneth A. Curr, Melissa Monaghan, Vasudev R. Rao, Snehlata Tripathi, Bradley D. Preston, Stefan Sarafianos, Eddy Arnold, Thomas Darden, and Vinayaka R. Prasad: Structural Determinants of Slippage-mediated Mutations by Human Immunodeficiency Virus Type 1 Reverse Transcriptase
J. Biol. Chem. 2006 281: 7421-7428. First Published on January 18, 2006; doi:10.1074/jbc.M511380200 [Abstract] [Full Text] [PDF]

Genes: Structure and Regulation:

Geetu Mendiratta, Peter R. Eriksson, Chang-Hui Shen, and David J. Clark: The DNA-binding Domain of the Yeast Spt10p Activator Includes a Zinc Finger That Is Homologous to Foamy Virus Integrase
J. Biol. Chem. 2006 281: 7040-7048. First Published on January 16, 2006; doi:10.1074/jbc.M511416200 [Abstract] [Full Text] [PDF]

Wilson Terán, Tino Krell, Juan Luis Ramos, and María-Trinidad Gallegos: Effector-Repressor Interactions, Binding of a Single Effector Molecule to the Operator-bound TtgR Homodimer Mediates Derepression
J. Biol. Chem. 2006 281: 7102-7109. First Published on January 5, 2006; doi:10.1074/jbc.M511095200 [Abstract] [Full Text] [PDF]

Jim Vadolas, Mikhail Nefedov, Hady Wardan, Sima Mansooriderakshan, Lucille Voullaire, Duangporn Jamsai, Robert Williamson, and Panayiotis A. Ioannou: Humanized $beta$ -Thalassemia Mouse Model Containing the Common IVSI-110 Splicing Mutation
J. Biol. Chem. 2006 281: 7399-7405. First Published on January 18, 2006; doi:10.1074/jbc.M512931200 [Abstract] [Full Text] [PDF]

George A. Kassavetis and David F. Steiner: Nhp6 Is a Transcriptional Initiation Fidelity Factor for RNA Polymerase III Transcription in Vitro and in Vivo
J. Biol. Chem. 2006 281: 7445-7451. First Published on January 11, 2006; doi:10.1074/jbc.M512810200 [Abstract] [Full Text] [PDF]

Eun A. Kim, Yoon Tae Noh, Myung-Jeom Ryu, Hyun-Taek Kim, Sung-Eun Lee, Cheol-Hee Kim, Cheolju Lee, Young Ho Kim, and Cheol Yong Choi: Phosphorylation and Transactivation of Pax6 by Homeodomain-interacting Protein Kinase 2
J. Biol. Chem. 2006 281: 7489-7497. First Published on January 9, 2006; doi:10.1074/jbc.M507227200 [Abstract] [Full Text] [PDF]

Protein Synthesis, Post-Translation Modification, and Degradation:

Norma M. Wills, Barry Moore, Andrew Hammer, Raymond F. Gesteland, and John F. Atkins: A Functional –1 Ribosomal Frameshift Signal in the Human Paraneoplastic Ma3 Gene
J. Biol. Chem. 2006 281: 7082-7088. First Published on January 5, 2006; doi:10.1074/jbc.M511629200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Ian T. Struewing, Agata Toborek, and Catherine D. Mao: Mitochondrial and Nuclear Forms of Wnt13 Are Generated via Alternative Promoters, Alternative RNA Splicing, and Alternative Translation Start Sites
J. Biol. Chem. 2006 281: 7282-7293. First Published on January 6, 2006; doi:10.1074/jbc.M511182200 [Abstract] [Full Text] [PDF]

Zhang-qun Chen, Jinsheng Dong, Akihiko Ishimura, Ira Daar, Alan G. Hinnebusch, and Michael Dean: The Essential Vertebrate ABCE1 Protein Interacts with Eukaryotic Initiation Factors
J. Biol. Chem. 2006 281: 7452-7457. First Published on January 18, 2006; doi:10.1074/jbc.M510603200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Stephanie Neumann, Susanne Schöbel, Sebastian Jäger, Anna Trautwein, Christian Haass, Claus U. Pietrzik, and Stefan F. Lichtenthaler: Amyloid Precursor-like Protein 1 Influences Endocytosis and Proteolytic Processing of the Amyloid Precursor Protein
J. Biol. Chem. 2006 281: 7583-7594. First Published on December 12, 2005; doi:10.1074/jbc.M508340200 [Abstract] [Full Text] [PDF]

Genomics, Proteomics, and Bioinformatics:

Thomas C. Wood, Oreste E. Salavagionne, Baidehi Mukherjee, Liewei Wang, Annette F. Klumpp, Bianca A. Thomae, Bruce W. Eckloff, Daniel J. Schaid, Eric D. Wieben, and Richard M. Weinshilboum: Human Arsenic Methyltransferase (AS3MT) Pharmacogenetics: GENE RESEQUENCING AND FUNCTIONAL GENOMICS STUDIES
J. Biol. Chem. 2006 281: 7364-7373. First Published on January 6, 2006; doi:10.1074/jbc.M512227200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Protein Structure and Folding:

Sun Ok Yoon, Tae Sup Lee, Sang Jick Kim, Myung Hee Jang, Young Jun Kang, Jae Hyun Park, Keun-Soo Kim, Hyun Sil Lee, Chun Jeih Ryu, Noreen R. Gonzales, Syed V. S. Kashmiri, Sang Moo Lim, Chang Woon Choi, and Hyo Jeong Hong: Construction, Affinity Maturation, and Biological Characterization of an Anti-tumor-associated Glycoprotein-72 Humanized Antibody
J. Biol. Chem. 2006 281: 6985-6992. First Published on January 9, 2006; doi:10.1074/jbc.M511165200 [Abstract] [Full Text] [PDF]

Peter C. Stirling, Jorge Cuéllar, Gabriel A. Alfaro, Fatima El Khadali, Christopher T. Beh, José M. Valpuesta, Ronald Melki, and Michel R. Leroux: PhLP3 Modulates CCT-mediated Actin and Tubulin Folding via Ternary Complexes with Substrates
J. Biol. Chem. 2006 281: 7012-7021. First Published on January 16, 2006; doi:10.1074/jbc.M513235200 [Abstract] [Full Text] [PDF]

Szymon Zietkiewicz, Agnieszka Lewandowska, Pawel Stocki, and Krzysztof Liberek: Hsp70 Chaperone Machine Remodels Protein Aggregates at the Initial Step of Hsp70-Hsp100-dependent Disaggregation
J. Biol. Chem. 2006 281: 7022-7029. First Published on January 16, 2006; doi:10.1074/jbc.M507893200 [Abstract] [Full Text] [PDF]

Ranveig Braathen, Anders Sandvik, Gøril Berntzen, Sven Hammerschmidt, Burkhard Fleckenstein, Inger Sandlie, Per Brandtzaeg, Finn-Eirik Johansen, and Vigdis Lauvrak: Identification of a Polymeric Ig Receptor Binding Phage-displayed Peptide That Exploits Epithelial Transcytosis without Dimeric IgA Competition
J. Biol. Chem. 2006 281: 7075-7081. First Published on January 19, 2006; doi:10.1074/jbc.M508509200 [Abstract] [Full Text] [PDF]

Parul Mishra, Md. Sohail Akhtar, and Vinod Bhakuni: Unusual Structural Features of the Bacteriophage-associated Hyaluronate Lyase (hylp2)
J. Biol. Chem. 2006 281: 7143-7150. First Published on January 16, 2006; doi:10.1074/jbc.M510991200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Francesca Cantini, Silvana Savino, Maria Scarselli, Vega Masignani, Mariagrazia Pizza, Giacomo Romagnoli, Erwin Swennen, Daniele Veggi, Lucia Banci, and Rino Rappuoli: Solution Structure of the Immunodominant Domain of Protective Antigen GNA1870 of Neisseria meningitidis
J. Biol. Chem. 2006 281: 7220-7227. First Published on December 31, 2005; doi:10.1074/jbc.M508595200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Michal Otyepka, Iveta Bártová, Zdenek Kríz, and Jaroslav Koca: Different Mechanisms of CDK5 and CDK2 Activation as Revealed by CDK5/p25 and CDK2/Cyclin A Dynamics
J. Biol. Chem. 2006 281: 7271-7281. First Published on January 9, 2006; doi:10.1074/jbc.M509699200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Finn L. Aachmann, Britt I. G. Svanem, Peter Güntert, Steffen B. Petersen, Svein Valla, and Reinhard Wimmer: NMR Structure of the R-module: A PARALLEL $beta$ -ROLL SUBUNIT FROM AN AZOTOBACTER VINELANDII MANNURONAN C-5 EPIMERASE
J. Biol. Chem. 2006 281: 7350-7356. First Published on January 3, 2006; doi:10.1074/jbc.M510069200 [Abstract] [Full Text] [PDF]

Vanesa Fernández-Sáiz, Fernando Moro, Jesus M. Arizmendi, Sergio P. Acebrón, and Arturo Muga: Ionic Contacts at DnaK Substrate Binding Domain Involved in the Allosteric Regulation of Lid Dynamics
J. Biol. Chem. 2006 281: 7479-7488. First Published on January 16, 2006; doi:10.1074/jbc.M512744200 [Abstract] [Full Text] [PDF]

Michael R. Sawaya, Gordon C. Cannon, Sabine Heinhorst, Shiho Tanaka, Eric B. Williams, Todd O. Yeates, and Cheryl A. Kerfeld: The Structure of $beta$ -Carbonic Anhydrase from the Carboxysomal Shell Reveals a Distinct Subclass with One Active Site for the Price of Two
J. Biol. Chem. 2006 281: 7546-7555. First Published on January 10, 2006; doi:10.1074/jbc.M510464200 [Abstract] [Full Text] [PDF]

Sheng-Chia Chen, Yuan-Chih Chang, Chao-Hsiung Lin, Chun-Hung Lin, and Shwu-Huey Liaw: Crystal Structure of a Bifunctional Deaminase and Reductase from Bacillus subtilis Involved in Riboflavin Biosynthesis
J. Biol. Chem. 2006 281: 7605-7613. First Published on November 24, 2005; doi:10.1074/jbc.M510254200 [Abstract] [Full Text] [PDF]

Paul Rowland, Frank E. Blaney, Martin G. Smyth, Jo J. Jones, Vaughan R. Leydon, Amanda K. Oxbrow, Ceri J. Lewis, Mike G. Tennant, Sandeep Modi, Drake S. Eggleston, Richard J. Chenery, and Angela M. Bridges: Crystal Structure of Human Cytochrome P450 2D6
J. Biol. Chem. 2006 281: 7614-7622. First Published on December 13, 2005; doi:10.1074/jbc.M511232200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Enzyme Catalysis and Regulation:

Choonkeun Kim, Joo Young Cha, Honggao Yan, Sergei B. Vakulenko, and Shahriar Mobashery: Hydrolysis of ATP by Aminoglycoside 3'-Phosphotransferases: AN UNEXPECTED COST TO BACTERIA FOR HARBORING AN ANTIBIOTIC RESISTANCE ENZYME
J. Biol. Chem. 2006 281: 6964-6969. First Published on January 3, 2006; doi:10.1074/jbc.M513257200 [Abstract] [Full Text] [PDF]

Robyn Richie-Jannetta, Jennifer L. Busch, Kristin A. Higgins, Jackie D. Corbin, and Sharron H. Francis: Isolated Regulatory Domains of cGMP-dependent Protein Kinase I ${alpha}$ and I $beta$ Retain Dimerization and Native cGMP-binding Properties and Undergo Isoform-specific Conformational Changes
J. Biol. Chem. 2006 281: 6977-6984. First Published on January 9, 2006; doi:10.1074/jbc.M510886200 [Abstract] [Full Text] [PDF]

Jeffrey Sabina and Dieter Söll: The RNA-binding PUA Domain of Archaeal tRNA-Guanine Transglycosylase Is Not Required for Archaeosine Formation
J. Biol. Chem. 2006 281: 6993-7001. First Published on January 10, 2006; doi:10.1074/jbc.M512841200 [Abstract] [Full Text] [PDF]

Shinya Watanabe, Reiko Ikebe, and Mitsuo Ikebe: Drosophila Myosin VIIA Is a High Duty Ratio Motor with a Unique Kinetic Mechanism
J. Biol. Chem. 2006 281: 7151-7160. First Published on January 16, 2006; doi:10.1074/jbc.M511592200 [Abstract] [Full Text] [PDF]

Quan Sha, Colvin M. Redman, and Soohee Lee: Endothelin-3-converting Enzyme Activity of the KEL1 and KEL6 Phenotypes of the Kell Blood Group System
J. Biol. Chem. 2006 281: 7180-7182. First Published on January 19, 2006; doi:10.1074/jbc.M507776200 [Abstract] [Full Text] [PDF]

Leslie A. Bush, Ryan W. Nelson, and Enrico Di Cera: Murine Thrombin Lacks Na⁺ Activation but Retains High Catalytic Activity
J. Biol. Chem. 2006 281: 7183-7188. First Published on January 20, 2006; doi:10.1074/jbc.M512082200 [Abstract] [Full Text] [PDF]

Conrad Yap Edosada, Clifford Quan, Christian Wiesmann, Thuy Tran, Dan Sutherlin, Mark Reynolds, J. Michael Elliott, Helga Raab, Wayne Fairbrother, and Beni B. Wolf: Selective Inhibition of Fibroblast Activation Protein Protease Based on Dipeptide Substrate Specificity
J. Biol. Chem. 2006 281: 7437-7444. First Published on January 12, 2006; doi:10.1074/jbc.M511112200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Yong-Zheng Wu, Yefim Manevich, James L. Baldwin, Chandra Dodia, Kevin Yu, Sheldon I. Feinstein, and Aron B. Fisher: Interaction of Surfactant Protein A with Peroxiredoxin 6 Regulates Phospholipase A₂ Activity
J. Biol. Chem. 2006 281: 7515-7525. First Published on December 5, 2005; doi:10.1074/jbc.M504525200 [Abstract] [Full Text] [PDF]

Zhuji Fu, Jennifer A. Runquist, Farhad Forouhar, Munif Hussain, John F. Hunt, Henry M. Miziorko, and Jung-Ja P. Kim: Crystal Structure of Human 3-Hydroxy-3-methylglutaryl-CoA Lyase: INSIGHTS INTO CATALYSIS AND THE MOLECULAR BASIS FOR HYDROXYMETHYLGLUTARIC ACIDURIA
J. Biol. Chem. 2006 281: 7526-7532. First Published on December 5, 2005; doi:10.1074/jbc.M506880200 [Abstract] [Full Text] [PDF]

Farhad Forouhar, Munif Hussain, Ramy Farid, Jordi Benach, Mariam Abashidze, William C. Edstrom, Sergey M. Vorobiev, Rong Xiao, Thomas B. Acton, Zhuji Fu, Jung-Ja P. Kim, Henry M. Miziorko, Gaetano T. Montelione, and John F. Hunt: Crystal Structures of Two Bacterial 3-Hydroxy-3-methylglutaryl-CoA Lyases Suggest a Common Catalytic Mechanism among a Family of TIM Barrel Metalloenzymes Cleaving Carbon-Carbon Bonds
J. Biol. Chem. 2006 281: 7533-7545. First Published on December 5, 2005; doi:10.1074/jbc.M507996200 [Abstract] [Full Text] [PDF]

Nadia Rabah, Dany Gauthier, Brian C. Wilkes, Daniel J. Gauthier, and Claude Lazure: Single Amino Acid Substitution in the PC1/3 Propeptide Can Induce Significant Modifications of Its Inhibitory Profile toward Its Cognate Enzyme
J. Biol. Chem. 2006 281: 7556-7567. First Published on January 11, 2006; doi:10.1074/jbc.M510607200 [Abstract] [Full Text] [PDF]

Olga Khersonsky and Dan S. Tawfik: The Histidine 115-Histidine 134 Dyad Mediates the Lactonase Activity of Mammalian Serum Paraoxonases
J. Biol. Chem. 2006 281: 7649-7656. First Published on January 10, 2006; doi:10.1074/jbc.M512594200 [Abstract] [Full Text] [PDF]

Metabolism and Bioenergetics:

Marie-Louise Sentman, Micael Granström, Håkan Jakobson, Andrew Reaume, Samar Basu, and Stefan L. Marklund: Phenotypes of Mice Lacking Extracellular Superoxide Dismutase and Copper- and Zinc-containing Superoxide Dismutase
J. Biol. Chem. 2006 281: 6904-6909. First Published on December 23, 2005; doi:10.1074/jbc.M510764200 [Abstract] [Full Text] [PDF]

Martha E. Gadd, Kimberly M. Broekemeier, Elliott D. Crouser, Jitendra Kumar, Gustav Graff, and Douglas R. Pfeiffer: Mitochondrial iPLA₂ Activity Modulates the Release of Cytochrome c from Mitochondria and Influences the Permeability Transition
J. Biol. Chem. 2006 281: 6931-6939. First Published on January 2, 2006; doi:10.1074/jbc.M510845200 [Abstract] [Full Text] [PDF]

Peter Schönfeld and Georg Reiser: Rotenone-like Action of the Branched-chain Phytanic Acid Induces Oxidative Stress in Mitochondria
J. Biol. Chem. 2006 281: 7136-7142. First Published on January 12, 2006; doi:10.1074/jbc.M513198200 [Abstract] [Full Text] [PDF]

Elisabeth C. Nilsson, Yun Chau Long, Sofia Martinsson, Stephan Glund, Pablo Garcia-Roves, L. Thomas Svensson, Leif Andersson, Juleen R. Zierath, and Margit Mahlapuu: Opposite Transcriptional Regulation in Skeletal Muscle of AMP-activated Protein Kinase ${gamma}$ 3 R225Q Transgenic Versus Knock-out Mice
J. Biol. Chem. 2006 281: 7244-7252. First Published on January 12, 2006; doi:10.1074/jbc.M510461200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Rob Horsefield, Victoria Yankovskaya, Graham Sexton, William Whittingham, Kazuro Shiomi, Satoshi Omura, Bernadette Byrne, Gary Cecchini, and So Iwata: Structural and Computational Analysis of the Quinone-binding Site of Complex II (Succinate-Ubiquinone Oxidoreductase): A MECHANISM OF ELECTRON TRANSFER AND PROTON CONDUCTION DURING UBIQUINONE REDUCTION
J. Biol. Chem. 2006 281: 7309-7316. First Published on December 27, 2005; doi:10.1074/jbc.M508173200 [Abstract] [Full Text] [PDF]

Glycobiology and Extracellular Matrices:

Lynda M. McDowell, Beth A. Frazier, Daniel R. Studelska, Kari Giljum, Jinghua Chen, Jian Liu, Kai Yu, David M. Ornitz, and Lijuan Zhang: Inhibition or Activation of Apert Syndrome FGFR2 (S252W) Signaling by Specific Glycosaminoglycans
J. Biol. Chem. 2006 281: 6924-6930. First Published on December 22, 2005; doi:10.1074/jbc.M512932200 [Abstract] [Full Text] [PDF]

James N. Arnold, Russell Wallis, Antony C. Willis, David J. Harvey, Louise Royle, Raymond A. Dwek, Pauline M. Rudd, and Robert B. Sim: Interaction of Mannan Binding Lectin with ${alpha}$ ₂ Macroglobulin via Exposed Oligomannose Glycans: A CONSERVED FEATURE OF THE THIOL ESTER PROTEIN FAMILY?
J. Biol. Chem. 2006 281: 6955-6963. First Published on January 5, 2006; doi:10.1074/jbc.M511432200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Alban Gaultier, Ana Maria Salicioni, Sanja Arandjelovic, and Steven L. Gonias: Regulation of the Composition of the Extracellular Matrix by Low Density Lipoprotein Receptor-related Protein-1: ACTIVITIES BASED ON REGULATION OF mRNA EXPRESSION
J. Biol. Chem. 2006 281: 7332-7340. First Published on January 6, 2006; doi:10.1074/jbc.M511857200 [Abstract] [Full Text] [PDF]

Justin M. Allen, John F. Bateman, Uwe Hansen, Richard Wilson, Peter Bruckner, Rick T. Owens, Takako Sasaki, Rupert Timpl, and Jamie Fitzgerald: WARP Is a Novel Multimeric Component of the Chondrocyte Pericellular Matrix That Interacts with Perlecan
J. Biol. Chem. 2006 281: 7341-7349. First Published on January 6, 2006; doi:10.1074/jbc.M513746200 [Abstract] [Full Text] [PDF]

Lipids and Lipoproteins:

Chan-Seok Oh and Charles E. Martin: Candida albicans Spt23p Controls the Expression of the Ole1p ${Delta}$ 9 Fatty Acid Desaturase and Regulates Unsaturated Fatty Acid Biosynthesis
J. Biol. Chem. 2006 281: 7030-7039. First Published on January 16, 2006; doi:10.1074/jbc.M510746200 [Abstract] [Full Text] [PDF]

Peter Christmas, Karine Tolentino, Valeria Primo, Karin Zemski Berry, Robert C. Murphy, Mei Chen, David M. Lee, and Roy J. Soberman: Cytochrome P-450 4F18 Is the Leukotriene B₄ ${omega}$ -1/ ${omega}$ -2 Hydroxylase in Mouse Polymorphonuclear Leukocytes: IDENTIFICATION AS THE FUNCTIONAL ORTHOLOGUE OF HUMAN POLYMORPHONUCLEAR LEUKOCYTE CYP4F3A IN THE DOWN-REGULATION OF RESPONSES TO LTB₄
J. Biol. Chem. 2006 281: 7189-7196. First Published on December 27, 2005; doi:10.1074/jbc.M513101200 [Abstract] [Full Text] [PDF]

Florence Bietrix, Daoguang Yan, Michel Nauze, Corinne Rolland, Justine Bertrand-Michel, Christine Coméra, Stephane Schaak, Ronald Barbaras, Albert K. Groen, Bertrand Perret, François Tercé, and Xavier Collet: Accelerated Lipid Absorption in Mice Overexpressing Intestinal SR-BI
J. Biol. Chem. 2006 281: 7214-7219. First Published on January 18, 2006; doi:10.1074/jbc.M508868200 [Abstract] [Full Text] [PDF]

Mari Kono, Jennifer L. Dreier, Jessica M. Ellis, Maria L. Allende, Danielle N. Kalkofen, Kathleen M. Sanders, Jacek Bielawski, Alicja Bielawska, Yusuf A. Hannun, and Richard L. Proia: Neutral Ceramidase Encoded by the Asah2 Gene Is Essential for the Intestinal Degradation of Sphingolipids
J. Biol. Chem. 2006 281: 7324-7331. First Published on December 27, 2005; doi:10.1074/jbc.M508382200 [Abstract] [Full Text] [PDF]

Mira Rosenblat, Leonid Gaidukov, Olga Khersonsky, Jacob Vaya, Roni Oren, Dan S. Tawfik, and Michael Aviram: The Catalytic Histidine Dyad of High Density Lipoprotein-associated Serum Paraoxonase-1 (PON1) Is Essential for PON1-mediated Inhibition of Low Density Lipoprotein Oxidation and Stimulation of Macrophage Cholesterol Efflux
J. Biol. Chem. 2006 281: 7657-7665. First Published on January 10, 2006; doi:10.1074/jbc.M512595200 [Abstract] [Full Text] [PDF]

Membrane Transport, Structure, Function, and Biogenesis:

Laura L. Wootton and Francesco Michelangeli: The Effects of the Phenylalanine 256 to Valine Mutation on the Sensitivity of Sarcoplasmic/Endoplasmic Reticulum Ca²⁺ ATPase (SERCA) Ca²⁺ Pump Isoforms 1, 2, and 3 to Thapsigargin and Other Inhibitors
J. Biol. Chem. 2006 281: 6970-6976. First Published on January 6, 2006; doi:10.1074/jbc.M510978200 [Abstract] [Full Text] [PDF]

Gottfried Eisner, Michael Moser, Ute Schäfer, Konstanze Beck, and Matthias Müller: Alternate Recruitment of Signal Recognition Particle and Trigger Factor to the Signal Sequence of a Growing Nascent Polypeptide
J. Biol. Chem. 2006 281: 7172-7179. First Published on January 18, 2006; doi:10.1074/jbc.M511388200 [Abstract] [Full Text] [PDF]

Andreas Meyer, Sepehr Eskandari, Silke Grallath, and Doris Rentsch: AtGAT1, a High Affinity Transporter for ${gamma}$ -Aminobutyric Acid in Arabidopsis thaliana
J. Biol. Chem. 2006 281: 7197-7204. First Published on January 10, 2006; doi:10.1074/jbc.M510766200 [Abstract] [Full Text] [PDF]

Kenji Kuwasako, Yuan-Ning Cao, Chun-Ping Chu, Shuji Iwatsubo, Tanenao Eto, and Kazuo Kitamura: Functions of the Cytoplasmic Tails of the Human Receptor Activity-modifying Protein Components of Calcitonin Gene-related Peptide and Adrenomedullin Receptors
J. Biol. Chem. 2006 281: 7205-7213. First Published on January 11, 2006; doi:10.1074/jbc.M511147200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Linglin Xie, Daniel Boyle, Daniel Sanford, Philipp E. Scherer, Jeffrey E. Pessin, and Silvia Mora: Intracellular Trafficking and Secretion of Adiponectin Is Dependent on GGA-coated Vesicles
J. Biol. Chem. 2006 281: 7253-7259. First Published on December 29, 2005; doi:10.1074/jbc.M511313200 [Abstract] [Full Text] [PDF]

Abigail A. Soyombo, Sandra Tjon-Kon-Sang, Youssef Rbaibi, Enkelejda Bashllari, Jill Bisceglia, Shmuel Muallem, and Kirill Kiselyov: TRP-ML1 Regulates Lysosomal pH and Acidic Lysosomal Lipid Hydrolytic Activity
J. Biol. Chem. 2006 281: 7294-7301. First Published on December 16, 2005; doi:10.1074/jbc.M508211200 [Abstract] [Full Text] [PDF]

Nam Soo Joo, Toshiya Irokawa, Robert C. Robbins, and Jeffrey J. Wine: Hyposecretion, Not Hyperabsorption, Is the Basic Defect of Cystic Fibrosis Airway Glands
J. Biol. Chem. 2006 281: 7392-7398. First Published on January 12, 2006; doi:10.1074/jbc.M512766200 [Abstract] [Full Text] [PDF] [Summary]

Ulrich Zachariae, Thomas Klühspies, Sharmila De, Harald Engelhardt, and Kornelius Zeth: High Resolution Crystal Structures and Molecular Dynamics Studies Reveal Substrate Binding in the Porin Omp32
J. Biol. Chem. 2006 281: 7413-7420. First Published on January 23, 2006; doi:10.1074/jbc.M510939200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Heedeok Hong, Dimki R. Patel, Lukas K. Tamm, and Bert van den Berg: The Outer Membrane Protein OmpW Forms an Eight-stranded $beta$ -Barrel with a Hydrophobic Channel
J. Biol. Chem. 2006 281: 7568-7577. First Published on January 12, 2006; doi:10.1074/jbc.M512365200 [Abstract] [Full Text] [PDF]

Molecular Basis Of Cell and Developmental Biology:

Badia Bisbis, Frédéric Delmas, Jérôme Joubès, Adrien Sicard, Michel Hernould, Dirk Inzé, Armand Mouras, and Christian Chevalier: Cyclin-dependent Kinase (CDK) Inhibitors Regulate the CDK-Cyclin Complex Activities in Endoreduplicating Cells of Developing Tomato Fruit
J. Biol. Chem. 2006 281: 7374-7383. First Published on January 9, 2006; doi:10.1074/jbc.M506587200 [Abstract] [Full Text] [PDF]

Dongmei Wang, Hiroshi Masutani, Shin-ichi Oka, Toru Tanaka, Yuko Yamaguchi-Iwai, Hajime Nakamura, and Junji Yodoi: Control of Mitochondrial Outer Membrane Permeabilization and Bcl-xL Levels by Thioredoxin 2 in DT40 Cells
J. Biol. Chem. 2006 281: 7384-7391. First Published on January 9, 2006; doi:10.1074/jbc.M509876200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Robert Meller, Jennifer Anastasia Cameron, Daniel John Torrey, Corrin Erin Clayton, Andrea Nicole Ordonez, David Clifford Henshall, Manabu Minami, Clara Kay Schindler, Julie Anne Saugstad, and Roger Pancoast Simon: Rapid Degradation of Bim by the Ubiquitin-Proteasome Pathway Mediates Short-term Ischemic Tolerance in Cultured Neurons
J. Biol. Chem. 2006 281: 7429-7436. First Published on January 23, 2006; doi:10.1074/jbc.M512138200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Bipin Patel, Alexandre R. Gingras, Audrey A. Bobkov, L. Miya Fujimoto, Man Zhang, Robert C. Liddington, Daniela Mazzeo, Jonas Emsley, Gordon C. K. Roberts, Igor L. Barsukov, and David R. Critchley: The Activity of the Vinculin Binding Sites in Talin Is Influenced by the Stability of the Helical Bundles That Make Up The Talin Rod
J. Biol. Chem. 2006 281: 7458-7467. First Published on January 9, 2006; doi:10.1074/jbc.M508058200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Yumiko Urano, Masayuki Iiduka, Akinori Sugiyama, Hirotada Akiyama, Kouji Uzawa, Gaku Matsumoto, Yasushi Kawasaki, and Fumio Tashiro: Involvement of the Mouse Prp19 Gene in Neuronal/Astroglial Cell Fate Decisions
J. Biol. Chem. 2006 281: 7498-7514. First Published on December 13, 2005; doi:10.1074/jbc.M510881200 [Abstract] [Full Text] [PDF]

Sasa Stefanic, Daniel Palm, Staffan G. Svärd, and Adrian B. Hehl: Organelle Proteomics Reveals Cargo Maturation Mechanisms Associated with Golgi-like Encystation Vesicles in the Early-diverged Protozoan Giardia lamblia
J. Biol. Chem. 2006 281: 7595-7604. First Published on January 3, 2006; doi:10.1074/jbc.M510940200 [Abstract] [Full Text] [PDF]

Cathárine C. Calkins, Shannon V. Setzer, Jean Marie Jennings, Susan Summers, Kazuyuki Tsunoda, Masayuki Amagai, and Andrew P. Kowalczyk: Desmoglein Endocytosis and Desmosome Disassembly Are Coordinated Responses to Pemphigus Autoantibodies
J. Biol. Chem. 2006 281: 7623-7634. First Published on December 23, 2005; doi:10.1074/jbc.M512447200 [Abstract] [Full Text] [PDF]

Meagan J. McGrath, Denny L. Cottle, Mai-Anh Nguyen, Jennifer M. Dyson, Imogen D. Coghill, Paul A. Robinson, Melissa Holdsworth, Belinda S. Cowling, Edna C. Hardeman, Christina A. Mitchell, and Susan Brown: Four and a Half LIM Protein 1 Binds Myosin-binding Protein C and Regulates Myosin Filament Formation and Sarcomere Assembly
J. Biol. Chem. 2006 281: 7666-7683. First Published on January 9, 2006; doi:10.1074/jbc.M512552200 [Abstract] [Full Text] [PDF]

Mechanisms Of Signal Transduction:

Emmanuelle Adam, Kristina K. Hansen, Olaya Fernandez Astudillo, Ludivine Coulon, Françoise Bex, Xavier Duhant, Erika Jaumotte, Morley D. Hollenberg, and Alain Jacquet: The House Dust Mite Allergen Der p 1, Unlike Der p 3, Stimulates the Expression of Interleukin-8 in Human Airway Epithelial Cells via a Proteinase-activated Receptor-2-independent Mechanism
J. Biol. Chem. 2006 281: 6910-6923. First Published on November 17, 2005; doi:10.1074/jbc.M507140200 [Abstract] [Full Text] [PDF]

Patrick Vincent, Elena Priceputu, Denis Kay, Kalle Saksela, Paul Jolicoeur, and Zaher Hanna: Activation of p21-activated Kinase 2 and Its Association with Nef Are Conserved in Murine Cells but Are Not Sufficient to Induce an AIDS-like Disease in CD4C/HIV Transgenic Mice
J. Biol. Chem. 2006 281: 6940-6954. First Published on December 28, 2005; doi:10.1074/jbc.M512710200 [Abstract] [Full Text] [PDF]

Xiaohui Lu, Alec W. Gross, and Harvey F. Lodish: Active Conformation of the Erythropoietin Receptor: RANDOM AND CYSTEINE-SCANNING MUTAGENESIS OF THE EXTRACELLULAR JUXTAMEMBRANE AND TRANSMEMBRANE DOMAINS
J. Biol. Chem. 2006 281: 7002-7011. First Published on January 12, 2006; doi:10.1074/jbc.M512638200 [Abstract] [Full Text] [PDF]

Soon-Young Choi, Min-Jung Kim, Chang-Mo Kang, Sangwoo Bae, Chul-Koo Cho, Jae-Won Soh, Jae-Hong Kim, Seongman Kang, Hee Yong Chung, Yun-Sil Lee, and Su-Jae Lee: Activation of Bak and Bax through c-Abl-Protein Kinase C ${delta}$ -p38 MAPK Signaling in Response to Ionizing Radiation in Human Non-small Cell Lung Cancer Cells
J. Biol. Chem. 2006 281: 7049-7059. First Published on January 12, 2006; doi:10.1074/jbc.M512000200 [Abstract] [Full Text] [PDF]

Cora Weigert, Anita M. Hennige, Rainer Lehmann, Katrin Brodbeck, Frank Baumgartner, Myriam Schaüble, Hans U. Häring, and Erwin D. Schleicher: Direct Cross-talk of Interleukin-6 and Insulin Signal Transduction via Insulin Receptor Substrate-1 in Skeletal Muscle Cells
J. Biol. Chem. 2006 281: 7060-7067. First Published on January 17, 2006; doi:10.1074/jbc.M509782200 [Abstract] [Full Text] [PDF]

David A. Proia, Bonnie W. Nannenga, Lawrence A. Donehower, and Nancy L. Weigel: Dual Roles for the Phosphatase PPM1D in Regulating Progesterone Receptor Function
J. Biol. Chem. 2006 281: 7089-7101. First Published on December 13, 2005; doi:10.1074/jbc.M511839200 [Abstract] [Full Text] [PDF]

Carla Amici, Antonio Rossi, Antonio Costanzo, Stefania Ciafrè, Barbara Marinari, Mirna Balsamo, Massimo Levrero, and M. Gabriella Santoro: Herpes Simplex Virus Disrupts NF- ${kappa}$ B Regulation by Blocking Its Recruitment on the I ${kappa}$ B ${alpha}$ Promoter and Directing the Factor on Viral Genes
J. Biol. Chem. 2006 281: 7110-7117. First Published on January 3, 2006; doi:10.1074/jbc.M512366200 [Abstract] [Full Text] [PDF]

Meng Qiao, Paul Shapiro, Matthew Fosbrink, Horea Rus, Rakesh Kumar, and Antonino Passaniti: Cell Cycle-dependent Phosphorylation of the RUNX2 Transcription Factor by cdc2 Regulates Endothelial Cell Proliferation
J. Biol. Chem. 2006 281: 7118-7128. First Published on January 9, 2006; doi:10.1074/jbc.M508162200 [Abstract] [Full Text] [PDF]

Kotaro Hattori, Shigeo Uchino, Tomoko Isosaka, Mamiko Maekawa, Masaomi Iyo, Toshio Sato, Shinichi Kohsaka, Takeshi Yagi, and Shigeki Yuasa: Fyn Is Required for Haloperidol-induced Catalepsy in Mice
J. Biol. Chem. 2006 281: 7129-7135. First Published on January 10, 2006; doi:10.1074/jbc.M511608200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Rudi K. Allan, Danny Mok, Bryan K. Ward, and Thomas Ratajczak: Modulation of Chaperone Function and Cochaperone Interaction by Novobiocin in the C-terminal Domain of Hsp90: EVIDENCE THAT COUMARIN ANTIBIOTICS DISRUPT Hsp90 DIMERIZATION
J. Biol. Chem. 2006 281: 7161-7171. First Published on January 17, 2006; doi:10.1074/jbc.M512406200 [Abstract] [Full Text] [PDF]

Philippe R. J. Bois, Brendan P. O'Hara, Daniel Nietlispach, John Kirkpatrick, and Tina Izard: The Vinculin Binding Sites of Talin and ${alpha}$ -Actinin Are Sufficient to Activate Vinculin
J. Biol. Chem. 2006 281: 7228-7236. First Published on January 9, 2006; doi:10.1074/jbc.M510397200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Stacey K. Ogden, David J. Casso, Manuel Ascano, Jr., Mark M. Yore, Thomas B. Kornberg, and David J. Robbins: Smoothened Regulates Activator and Repressor Functions of Hedgehog Signaling via Two Distinct Mechanisms
J. Biol. Chem. 2006 281: 7237-7243. First Published on January 19, 2006; doi:10.1074/jbc.M510169200 [Abstract] [Full Text] [PDF]

Jianze Li, Brenda Lee, and Amy S. Lee: Endoplasmic Reticulum Stress-induced Apoptosis: MULTIPLE PATHWAYS AND ACTIVATION OF p53-UP-REGULATED MODULATOR OF APOPTOSIS (PUMA) AND NOXA BY p53
J. Biol. Chem. 2006 281: 7260-7270. First Published on January 6, 2006; doi:10.1074/jbc.M509868200 [Abstract] [Full Text] [PDF]

Mehul Shah, Kirit Patel, Somshuvra Mukhopadhyay, Fang Xu, Gary Guo, and Pravin B. Sehgal: Membrane-associated STAT3 and PY-STAT3 in the Cytoplasm
J. Biol. Chem. 2006 281: 7302-7308. First Published on December 31, 2005; doi:10.1074/jbc.M508527200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Ceniz Zihni, Costas Mitsopoulos, Ignatius A. Tavares, Anne J. Ridley, and Jonathan D. H. Morris: Prostate-derived Sterile 20-like Kinase 2 (PSK2) Regulates Apoptotic Morphology via C-Jun N-terminal Kinase and Rho Kinase-1
J. Biol. Chem. 2006 281: 7317-7323. First Published on January 2, 2006; doi:10.1074/jbc.M513769200 [Abstract] [Full Text] [PDF]

Rebecca A. Bachmann, Jeong-Ho Kim, Ai-Luen Wu, In-Hyun Park, and Jie Chen: A Nuclear Transport Signal in Mammalian Target of Rapamycin Is Critical for Its Cytoplasmic Signaling to S6 Kinase 1
J. Biol. Chem. 2006 281: 7357-7363. First Published on January 9, 2006; doi:10.1074/jbc.M512218200 [Abstract] [Full Text] [PDF]

Weiting Ge, Hanguang Hu, Kefeng Ding, Lifeng Sun, and Shu Zheng: Protein Interaction Analysis of ST14 Domains and Their Point and Deletion Mutants
J. Biol. Chem. 2006 281: 7406-7412. First Published on January 9, 2006; doi:10.1074/jbc.M510687200 [Abstract] [Full Text] [PDF]

Soo-Ho Choi and Soon B. Hwang: Modulation of the Transforming Growth Factor- $beta$ Signal Transduction Pathway by Hepatitis C Virus Nonstructural 5A Protein
J. Biol. Chem. 2006 281: 7468-7478. First Published on January 6, 2006; doi:10.1074/jbc.M512438200 [Abstract] [Full Text] [PDF]

Xuejun Tian and Larry A. Feig: Age-dependent Participation of Ras-GRF Proteins in Coupling Calcium-permeable AMPA Glutamate Receptors to Ras/Erk Signaling in Cortical Neurons
J. Biol. Chem. 2006 281: 7578-7582. First Published on January 11, 2006; doi:10.1074/jbc.M512060200 [Abstract] [Full Text] [PDF]

Kevin D. Ridge, Najmoutin G. Abdulaev, Cheng Zhang, Tony Ngo, Danielle M. Brabazon, and John P. Marino: Conformational Changes Associated with Receptor-stimulated Guanine Nucleotide Exchange in a Heterotrimeric G-protein ${alpha}$ -Subunit: NMR ANALYSIS OF GTP ${gamma}$ S-BOUND STATES
J. Biol. Chem. 2006 281: 7635-7648. First Published on January 9, 2006; doi:10.1074/jbc.M509851200 [Abstract] [Full Text] [PDF] [Supplemental Data]

David J. Vaughan, Ellen E. Millman, Veronica Godines, Jacqueline Friedman, Tuan M. Tran, Wenping Dai, Brian J. Knoll, Richard B. Clark, and Robert H. Moore: Role of the G Protein-coupled Receptor Kinase Site Serine Cluster in $beta$ ₂-Adrenergic Receptor Internalization, Desensitization, and $beta$ -Arrestin Translocation
J. Biol. Chem. 2006 281: 7684-7692. First Published on January 3, 2006; doi:10.1074/jbc.M500328200 [Abstract] [Full Text] [PDF]

All ASBMB Journals	Molecular and Cellular Proteomics
Journal of Lipid Research	ASBMB Today

Papers Of The Week:

Reflections:

DNA: Replication, Repair, and Recombination:

Genes: Structure and Regulation:

Protein Synthesis, Post-Translation Modification, and Degradation:

Genomics, Proteomics, and Bioinformatics:

Protein Structure and Folding:

Enzyme Catalysis and Regulation:

Metabolism and Bioenergetics:

Glycobiology and Extracellular Matrices:

Lipids and Lipoproteins:

Membrane Transport, Structure, Function, and Biogenesis:

Molecular Basis Of Cell and Developmental Biology:

Mechanisms Of Signal Transduction: