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The cover shows the crystal structure of an N-terminal fragment of the staphylocoagulase (SC-(1-325)) bound to bovine thrombin. SC-(1-325) (blue) is composed mainly of two- to three-helix bundles, and bovine thrombin (pink) is shown in standard Bode orientation. The image was created using Chimera (www.cgl.ucsf.edu/chimera). For details see the article by Friedrich et al., pages 1188–1195.

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