JBC -- Table of Contents (Aug 11 2006, 281, (32))

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Nicole Kresge, Robert D. Simoni, and Robert L. Hill: The Development of Two-dimensional Electrophoresis by Patrick H. O'Farrell
High resolution two-dimensional electrophoresis of proteins (P. H. O'Farrell J. Biol. Chem. 250, 4007-4021)
J. Biol. Chem. 2006 281: e26. [Full Text]

Minireviews:

Michael D. Gordon and Roel Nusse: Wnt Signaling: Multiple Pathways, Multiple Receptors, and Multiple Transcription Factors
J. Biol. Chem. 2006 281: 22429-22433. First Published on June 22, 2006; doi:10.1074/jbc.R600015200 [Full Text] [PDF]

Accelerated Publications:

Audur Magnusdottir, Pål Stenmark, Susanne Flodin, Tomas Nyman, Martin Hammarström, Maria Ehn, M Amin Bakali H, Helena Berglund, and Pär Nordlund: The Crystal Structure of a Human PP2A Phosphatase Activator Reveals a Novel Fold and Highly Conserved Cleft Implicated in Protein-Protein Interactions
J. Biol. Chem. 2006 281: 22434-22438. First Published on June 16, 2006; doi:10.1074/jbc.C600100200 [Abstract] [Full Text] [PDF]

DNA: Replication, Repair, and Recombination:

Luciana Amado and Andrei Kuzminov: The Replication Intermediates in Escherichia coli Are Not the Product of DNA Processing or Uracil Excision
J. Biol. Chem. 2006 281: 22635-22646. First Published on June 12, 2006; doi:10.1074/jbc.M602320200 [Abstract] [Full Text] [PDF]

Sally J. York and Paul Modrich: Mismatch Repair-dependent Iterative Excision at Irreparable O⁶-Methylguanine Lesions in Human Nuclear Extracts
J. Biol. Chem. 2006 281: 22674-22683. First Published on June 12, 2006; doi:10.1074/jbc.M603667200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Giovanna Pontarin, Paola Ferraro, Maria L. Valentino, Michio Hirano, Peter Reichard, and Vera Bianchi: Mitochondrial DNA Depletion and Thymidine Phosphate Pool Dynamics in a Cellular Model of Mitochondrial Neurogastrointestinal Encephalomyopathy
J. Biol. Chem. 2006 281: 22720-22728. First Published on June 13, 2006; doi:10.1074/jbc.M604498200 [Abstract] [Full Text] [PDF]

Marlène Maroun, Olivier Delelis, Gaël Coadou, Thomas Bader, Emmanuel Ségéral, Gladys Mbemba, Caroline Petit, Pierre Sonigo, Jean-Christophe Rain, Jean-François Mouscadet, Richard Benarous, and Stéphane Emiliani: Inhibition of Early Steps of HIV-1 Replication by SNF5/Ini1
J. Biol. Chem. 2006 281: 22736-22743. First Published on June 13, 2006; doi:10.1074/jbc.M604849200 [Abstract] [Full Text] [PDF] [Supplemental data]

Christine Ralf, Ian D. Hickson, and Leonard Wu: The Bloom's Syndrome Helicase Can Promote the Regression of a Model Replication Fork
J. Biol. Chem. 2006 281: 22839-22846. First Published on June 8, 2006; doi:10.1074/jbc.M604268200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Ilian Radichev, Sung Won Kwon, Yingming Zhao, Melvin L. DePamphilis, and Alex Vassilev: Genetic Analysis of Human Orc2 Reveals Specific Domains That Are Required in Vivo for Assembly and Nuclear Localization of the Origin Recognition Complex
J. Biol. Chem. 2006 281: 23264-23273. First Published on June 7, 2006; doi:10.1074/jbc.M603873200 [Abstract] [Full Text] [PDF]

Genes: Structure and Regulation:

Jianhua Wei, Ling Zhai, Jun Xu, and Hengbin Wang: Role of Bmi1 in H2A Ubiquitylation and Hox Gene Silencing
J. Biol. Chem. 2006 281: 22537-22544. First Published on June 4, 2006; doi:10.1074/jbc.M600826200 [Abstract] [Full Text] [PDF]

Jennifer J. Stewart, Julie A. Fischbeck, Xu Chen, and Laurie A. Stargell: Non-optimal TATA Elements Exhibit Diverse Mechanistic Consequences
J. Biol. Chem. 2006 281: 22665-22673. First Published on June 12, 2006; doi:10.1074/jbc.M603237200 [Abstract] [Full Text] [PDF]

Alejandro Villagra, Fernando Cruzat, Loreto Carvallo, Roberto Paredes, Juan Olate, Andre J. van Wijnen, Gary S. Stein, Jane B. Lian, Janet L. Stein, Anthony N. Imbalzano, and Martin Montecino: Chromatin Remodeling and Transcriptional Activity of the Bone-specific Osteocalcin Gene Require CCAAT/Enhancer-binding Protein $beta$ -dependent Recruitment of SWI/SNF Activity
J. Biol. Chem. 2006 281: 22695-22706. First Published on June 13, 2006; doi:10.1074/jbc.M511640200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Jose M. Rodriguez, Michele A. Glozak, Yihong Ma, and W. Douglas Cress: Bok, Bcl-2-related Ovarian Killer, Is Cell Cycle-regulated and Sensitizes to Stress-induced Apoptosis
J. Biol. Chem. 2006 281: 22729-22735. First Published on June 13, 2006; doi:10.1074/jbc.M604705200 [Abstract] [Full Text] [PDF]

José L. Carrasco, María José Castelló, and Pablo Vera: 14-3-3 Mediates Transcriptional Regulation by Modulating Nucleocytoplasmic Shuttling of Tobacco DNA-binding Protein Phosphatase-1
J. Biol. Chem. 2006 281: 22875-22881. First Published on June 8, 2006; doi:10.1074/jbc.M512611200 [Abstract] [Full Text] [PDF]

Duygu Dee Harrison-Findik, Denise Schafer, Elizabeth Klein, Nikolai A. Timchenko, Hasan Kulaksiz, Dahn Clemens, Evelyn Fein, Billy Andriopoulos, Kostas Pantopoulos, and John Gollan: Alcohol Metabolism-mediated Oxidative Stress Down-regulates Hepcidin Transcription and Leads to Increased Duodenal Iron Transporter Expression
J. Biol. Chem. 2006 281: 22974-22982. First Published on May 31, 2006; doi:10.1074/jbc.M602098200 [Abstract] [Full Text] [PDF]

Sandra Christen, Annapurna Srinivas, Priska Bähler, Anja Zeller, David Pridmore, Christoph Bieniossek, Ulrich Baumann, and Bernhard Erni: Regulation of the Dha Operon of Lactococcus lactis: A DEVIATION FROM THE RULE FOLLOWED BY THE TetR FAMILY OF TRANSCRIPTION REGULATORS
J. Biol. Chem. 2006 281: 23129-23137. First Published on June 7, 2006; doi:10.1074/jbc.M603486200 [Abstract] [Full Text] [PDF] [Supplemental Data]

RNA: Structure, Metabolism, and Catalysis:

Mayka Sanchez, Bruno Galy, Thomas Dandekar, Peter Bengert, Yevhen Vainshtein, Jens Stolte, Martina U. Muckenthaler, and Matthias W. Hentze: Iron Regulation and the Cell Cycle: IDENTIFICATION OF AN IRON-RESPONSIVE ELEMENT IN THE 3'-UNTRANSLATED REGION OF HUMAN CELL DIVISION CYCLE 14A mRNA BY A REFINED MICROARRAY-BASED SCREENING STRATEGY
J. Biol. Chem. 2006 281: 22865-22874. First Published on June 7, 2006; doi:10.1074/jbc.M603876200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Jennifer L. Hsu, Seung Bae Rho, Kevin M. Vannella, and Susan A. Martinis: Functional Divergence of a Unique C-terminal Domain of Leucyl-tRNA Synthetase to Accommodate Its Splicing and Aminoacylation Roles
J. Biol. Chem. 2006 281: 23075-23082. First Published on June 14, 2006; doi:10.1074/jbc.M601606200 [Abstract] [Full Text] [PDF]

Ekaterini C. Kouvela, Alexandros D. Petropoulos, and Dimitrios L. Kalpaxis: Unraveling New Features of Clindamycin Interaction with Functional Ribosomes and Dependence of the Drug Potency on Polyamines
J. Biol. Chem. 2006 281: 23103-23110. First Published on June 7, 2006; doi:10.1074/jbc.M603263200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Protein Synthesis, Post-Translation Modification, and Degradation:

Jaroslaw Zimny, Marta Sikora, Andrzej Guranowski, and Hieronim Jakubowski: Protective Mechanisms against Homocysteine Toxicity: THE ROLE OF BLEOMYCIN HYDROLASE
J. Biol. Chem. 2006 281: 22485-22492. First Published on June 12, 2006; doi:10.1074/jbc.M603656200 [Abstract] [Full Text] [PDF]

Aaron K. LeFebvre, Nadejda L. Korneeva, Marjan Trutschl, Urska Cvek, Roy D. Duzan, Christopher A. Bradley, John W. B. Hershey, and Robert E. Rhoads: Translation Initiation Factor eIF4G-1 Binds to eIF3 through the eIF3e Subunit
J. Biol. Chem. 2006 281: 22917-22932. First Published on June 9, 2006; doi:10.1074/jbc.M605418200 [Abstract] [Full Text] [PDF]

Stephen S. Lin, Michael C. Bassik, Heikyung Suh, Mari Nishino, Jason D. Arroyo, William C. Hahn, Stanley J. Korsmeyer, and Thomas M. Roberts: PP2A Regulates BCL-2 Phosphorylation and Proteasome-mediated Degradation at the Endoplasmic Reticulum
J. Biol. Chem. 2006 281: 23003-23012. First Published on May 22, 2006; doi:10.1074/jbc.M602648200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Xi Mo, Nan Lu, Arnoldo Padilla, José A. López, and Renhao Li: The Transmembrane Domain of Glycoprotein Ib $beta$ Is Critical to Efficient Expression of Glycoprotein Ib-IX Complex in the Plasma Membrane
J. Biol. Chem. 2006 281: 23050-23059. First Published on June 6, 2006; doi:10.1074/jbc.M600924200 [Abstract] [Full Text] [PDF]

Dipankar Ray, Evan C. Osmundson, and Hiroaki Kiyokawa: Constitutive and UV-induced Fibronectin Degradation Is a Ubiquitination-dependent Process Controlled by $beta$ -TrCP
J. Biol. Chem. 2006 281: 23060-23065. First Published on June 6, 2006; doi:10.1074/jbc.M604311200 [Abstract] [Full Text] [PDF]

Yasuhiro Uchimura, Takaya Ichimura, Junsuke Uwada, Taro Tachibana, Satoko Sugahara, Mitsuyoshi Nakao, and Hisato Saitoh: Involvement of SUMO Modification in MBD1- and MCAF1-mediated Heterochromatin Formation
J. Biol. Chem. 2006 281: 23180-23190. First Published on June 5, 2006; doi:10.1074/jbc.M602280200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Kenyon D. Ogburn and Maria E. Figueiredo-Pereira: Cytoskeleton/Endoplasmic Reticulum Collapse Induced by Prostaglandin J2 Parallels Centrosomal Deposition of Ubiquitinated Protein Aggregates
J. Biol. Chem. 2006 281: 23274-23284. First Published on June 14, 2006; doi:10.1074/jbc.M600635200 [Abstract] [Full Text] [PDF]

Genomics, Proteomics, and Bioinformatics:

Wenlian Xu, Christopher A. Dunn, Suzanne F. O'Handley, Denise L. Smith, and Maurice J. Bessman: Three New Nudix Hydrolases from Escherichia coli
J. Biol. Chem. 2006 281: 22794-22798. First Published on June 9, 2006; doi:10.1074/jbc.M603407200 [Abstract] [Full Text] [PDF]

Protein Structure and Folding:

Xuewei S. Li, Jianing N. Sun, Kazuko Okamoto-Shibayama, and Mira Edgerton: Candida albicans Cell Wall Ssa Proteins Bind and Facilitate Import of Salivary Histatin 5 Required for Toxicity
J. Biol. Chem. 2006 281: 22453-22463. First Published on May 23, 2006; doi:10.1074/jbc.M604064200 [Abstract] [Full Text] [PDF]

Maura Camozzi, Marco Rusnati, Antonella Bugatti, Barbara Bottazzi, Alberto Mantovani, Antonio Bastone, Antonio Inforzato, Silvia Vincenti, Luisa Bracci, Domenico Mastroianni, and Marco Presta: Identification of an Antiangiogenic FGF2-binding Site in the N Terminus of the Soluble Pattern Recognition Receptor PTX3
J. Biol. Chem. 2006 281: 22605-22613. First Published on June 12, 2006; doi:10.1074/jbc.M601023200 [Abstract] [Full Text] [PDF]

Lauren R. Sheckler, Lisa Henry, Shuzo Sugita, Thomas C. Südhof, and Gabby Rudenko: Crystal Structure of the Second LNS/LG Domain from Neurexin 1 ${alpha}$ : Ca²⁺ BINDING AND THE EFFECTS OF ALTERNATIVE SPLICING
J. Biol. Chem. 2006 281: 22896-22905. First Published on June 13, 2006; doi:10.1074/jbc.M603464200 [Abstract] [Full Text] [PDF]

Joan L. Arolas, Sílvia Bronsoms, Salvador Ventura, Francesc X. Aviles, and Juan J. Calvete: Characterizing the Tick Carboxypeptidase Inhibitor: MOLECULAR BASIS FOR ITS TWO-DOMAIN NATURE
J. Biol. Chem. 2006 281: 22906-22916. First Published on June 7, 2006; doi:10.1074/jbc.M602301200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Ana Beloqui, Marcos Pita, Julio Polaina, Arturo Martínez-Arias, Olga V. Golyshina, Miren Zumárraga, Michail M. Yakimov, Humberto García-Arellano, Miguel Alcalde, Víctor M. Fernández, Kieran Elborough, José M. Andreu, Antonio Ballesteros, Francisco J. Plou, Kenneth N. Timmis, Manuel Ferrer, and Peter N. Golyshin: Novel Polyphenol Oxidase Mined from a Metagenome Expression Library of Bovine Rumen: BIOCHEMICAL PROPERTIES, STRUCTURAL ANALYSIS, AND PHYLOGENETIC RELATIONSHIPS
J. Biol. Chem. 2006 281: 22933-22942. First Published on June 1, 2006; doi:10.1074/jbc.M600577200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Michelle M. Pesho, Kamila Bledzka, Lidia Michalec, Czeslaw S. Cierniewski, and Edward F. Plow: The Specificity and Function of the Metal-binding Sites in the Integrin $beta$ ₃ A-domain
J. Biol. Chem. 2006 281: 23034-23041. First Published on May 24, 2006; doi:10.1074/jbc.M602856200 [Abstract] [Full Text] [PDF]

Akhilesh K. Singh, Jayati Mullick, John Bernet, and Arvind Sahu: Functional Characterization of the Complement Control Protein Homolog of Herpesvirus Saimiri: ARG-118 IS CRITICAL FOR FACTOR I COFACTOR ACTIVITIES
J. Biol. Chem. 2006 281: 23119-23128. First Published on June 7, 2006; doi:10.1074/jbc.M603085200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Richard J. Clark, Harald Fischer, Simon T. Nevin, David J. Adams, and David J. Craik: The Synthesis, Structural Characterization, and Receptor Specificity of the ${alpha}$ -Conotoxin Vc1.1
J. Biol. Chem. 2006 281: 23254-23263. First Published on June 5, 2006; doi:10.1074/jbc.M604550200 [Abstract] [Full Text] [PDF]

Enzyme Catalysis and Regulation:

Olivier Berteau, Alain Guillot, Alhosna Benjdia, and Sylvie Rabot: A New Type of Bacterial Sulfatase Reveals a Novel Maturation Pathway in Prokaryotes
J. Biol. Chem. 2006 281: 22464-22470. First Published on June 9, 2006; doi:10.1074/jbc.M602504200 [Abstract] [Full Text] [PDF]

Elvire Guiot, Kevin Carayon, Olivier Delelis, Françoise Simon, Patrick Tauc, Evgenii Zubin, Marina Gottikh, Jean-François Mouscadet, Jean-Claude Brochon, and Eric Deprez: Relationship between the Oligomeric Status of HIV-1 Integrase on DNA and Enzymatic Activity
J. Biol. Chem. 2006 281: 22707-22719. First Published on June 13, 2006; doi:10.1074/jbc.M602198200 [Abstract] [Full Text] [PDF]

Daniel L. Baker, Yuko Fujiwara, Kathryn R. Pigg, Ryoko Tsukahara, Susumu Kobayashi, Hiromu Murofushi, Ayako Uchiyama, Kimiko Murakami-Murofushi, Eunjin Koh, Russell W. Bandle, Hoe-Sup Byun, Robert Bittman, Dominic Fan, Mandi Murph, Gordon B. Mills, and Gabor Tigyi: Carba Analogs of Cyclic Phosphatidic Acid Are Selective Inhibitors of Autotaxin and Cancer Cell Invasion and Metastasis
J. Biol. Chem. 2006 281: 22786-22793. First Published on June 16, 2006; doi:10.1074/jbc.M512486200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Anton A. Turanov, Dan Su, and Vadim N. Gladyshev: Characterization of Alternative Cytosolic Forms and Cellular Targets of Mouse Mitochondrial Thioredoxin Reductase
J. Biol. Chem. 2006 281: 22953-22963. First Published on June 14, 2006; doi:10.1074/jbc.M604326200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Kasper D. Rand, Thomas J. D. Jørgensen, Ole H. Olsen, Egon Persson, Ole N. Jensen, Henning R. Stennicke, and Mette D. Andersen: Allosteric Activation of Coagulation Factor VIIa Visualized by Hydrogen Exchange
J. Biol. Chem. 2006 281: 23018-23024. First Published on May 10, 2006; doi:10.1074/jbc.M602968200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Pierre F. Neuenschwander, Stephen R. Williamson, Armen Nalian, and Kimberly J. Baker-Deadmond: Heparin Modulates the 99-Loop of Factor IXa: EFFECTS ON REACTIVITY WITH ISOLATED KUNITZ-TYPE INHIBITOR DOMAINS
J. Biol. Chem. 2006 281: 23066-23074. First Published on June 9, 2006; doi:10.1074/jbc.M603743200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Linda J. Roman and Bettie Sue S. Masters: Electron Transfer by Neuronal Nitric-oxide Synthase Is Regulated by Concerted Interaction of Calmodulin and Two Intrinsic Regulatory Elements
J. Biol. Chem. 2006 281: 23111-23118. First Published on June 16, 2006; doi:10.1074/jbc.M603671200 [Abstract] [Full Text] [PDF]

Kin-Yip Cheng, Martin E. M. Noble, Vicky Skamnaki, Nick R. Brown, Ed D. Lowe, Luke Kontogiannis, Kui Shen, Philip A. Cole, Giuliano Siligardi, and Louise N. Johnson: The Role of the Phospho-CDK2/Cyclin A Recruitment Site in Substrate Recognition
J. Biol. Chem. 2006 281: 23167-23179. First Published on May 17, 2006; doi:10.1074/jbc.M600480200 [Abstract] [Full Text] [PDF]

Ju-Yi Hsieh, Guang-Yaw Liu, Gu-Gang Chang, and Hui-Chih Hung: Determinants of the Dual Cofactor Specificity and Substrate Cooperativity of the Human Mitochondrial NAD(P)⁺-dependent Malic Enzyme: FUNCTIONAL ROLES OF GLUTAMINE 362
J. Biol. Chem. 2006 281: 23237-23245. First Published on June 6, 2006; doi:10.1074/jbc.M603451200 [Abstract] [Full Text] [PDF]

Metabolism and Bioenergetics:

Pawel Bieganowski, Heather F. Seidle, Marzena Wojcik, and Charles Brenner: Synthetic Lethal and Biochemical Analyses of NAD and NADH Kinases in Saccharomyces cerevisiae Establish Separation of Cellular Functions
J. Biol. Chem. 2006 281: 22439-22445. First Published on June 7, 2006; doi:10.1074/jbc.M513919200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Yan Zhang, Elise R. Lyver, Simon A. B. Knight, Debkumar Pain, Emmanuel Lesuisse, and Andrew Dancis: Mrs3p, Mrs4p, and Frataxin Provide Iron for Fe-S Cluster Synthesis in Mitochondria
J. Biol. Chem. 2006 281: 22493-22502. First Published on June 12, 2006; doi:10.1074/jbc.M604246200 [Abstract] [Full Text] [PDF]

Meriem El Ghachi, Ahmed Bouhss, Hélène Barreteau, Thierry Touzé, Geneviève Auger, Didier Blanot, and Dominique Mengin-Lecreulx: Colicin M Exerts Its Bacteriolytic Effect via Enzymatic Degradation of Undecaprenyl Phosphate-linked Peptidoglycan Precursors
J. Biol. Chem. 2006 281: 22761-22772. First Published on June 15, 2006; doi:10.1074/jbc.M602834200 [Abstract] [Full Text] [PDF]

Klaus Zwicker, Alexander Galkin, Stefan Dröse, Ljuban Grgic, Stefan Kerscher, and Ulrich Brandt: The Redox-Bohr Group Associated with Iron-Sulfur Cluster N2 of Complex I
J. Biol. Chem. 2006 281: 23013-23017. First Published on June 7, 2006; doi:10.1074/jbc.M603442200 [Abstract] [Full Text] [PDF]

Glycobiology and Extracellular Matrices:

Aneta Liwosz, Tianlei Lei, and Maria A. Kukuruzinska: N-Glycosylation Affects the Molecular Organization and Stability of E-cadherin Junctions
J. Biol. Chem. 2006 281: 23138-23149. First Published on May 8, 2006; doi:10.1074/jbc.M512621200 [Abstract] [Full Text] [PDF]

Erica Werner, Andrew P. Kowalczyk, and Victor Faundez: Anthrax Toxin Receptor 1/Tumor Endothelium Marker 8 Mediates Cell Spreading by Coupling Extracellular Ligands to the Actin Cytoskeleton
J. Biol. Chem. 2006 281: 23227-23236. First Published on June 8, 2006; doi:10.1074/jbc.M603676200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Lipids and Lipoproteins:

Jonathan E. Markham, Jia Li, Edgar B. Cahoon, and Jan G. Jaworski: Separation and Identification of Major Plant Sphingolipid Classes from Leaves
J. Biol. Chem. 2006 281: 22684-22694. First Published on June 12, 2006; doi:10.1074/jbc.M604050200 [Abstract] [Full Text] [PDF]

Maria L. Gaspar, Manuel A. Aregullin, Stephen A. Jesch, and Susan A. Henry: Inositol Induces a Profound Alteration in the Pattern and Rate of Synthesis and Turnover of Membrane Lipids in Saccharomyces cerevisiae
J. Biol. Chem. 2006 281: 22773-22785. First Published on June 15, 2006; doi:10.1074/jbc.M603548200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Jesse LoVerme, Manuel Guzmán, Silvana Gaetani, and Daniele Piomelli: Cold Exposure Stimulates Synthesis of the Bioactive Lipid Oleoylethanolamide in Rat Adipose Tissue
J. Biol. Chem. 2006 281: 22815-22818. First Published on June 19, 2006; doi:10.1074/jbc.M604751200 [Abstract] [Full Text] [PDF]

Susana Contreras-Alcantara, Jesse A. Godby, and Sue E. Delos: The Single Ligand-binding Repeat of Tva, a Low Density Lipoprotein Receptor-related Protein, Contains Two Ligand-binding Surfaces
J. Biol. Chem. 2006 281: 22827-22838. First Published on June 12, 2006; doi:10.1074/jbc.M512599200 [Abstract] [Full Text] [PDF]

Membrane Transport, Structure, Function, and Biogenesis:

E. Laura Sherman, Rebecca D. Taylor, Nancy E. Go, and Frank E. Nargang: Effect of Mutations in Tom40 on Stability of the Translocase of the Outer Mitochondrial Membrane (TOM) Complex, Assembly of Tom40, and Import of Mitochondrial Preproteins
J. Biol. Chem. 2006 281: 22554-22565. First Published on June 6, 2006; doi:10.1074/jbc.M601630200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Attila Kumánovics, Katherine E. Poruk, Katharine A. Osborn, Diane M. Ward, and Jerry Kaplan: YKE4 (YIL023C) Encodes a Bidirectional Zinc Transporter in the Endoplasmic Reticulum of Saccharomyces cerevisiae
J. Biol. Chem. 2006 281: 22566-22574. First Published on June 7, 2006; doi:10.1074/jbc.M604730200 [Abstract] [Full Text] [PDF]

Raquel Valdés, Wei Liu, Buddy Ullman, and Scott M. Landfear: Comprehensive Examination of Charged Intramembrane Residues in a Nucleoside Transporter
J. Biol. Chem. 2006 281: 22647-22655. First Published on June 12, 2006; doi:10.1074/jbc.M602366200 [Abstract] [Full Text] [PDF]

Masashi Ohira, Anne M. Smardon, Colleen M. H. Charsky, Jianzhong Liu, Maureen Tarsio, and Patricia M. Kane: The E and G Subunits of the Yeast V-ATPase Interact Tightly and Are Both Present at More Than One Copy per V₁ Complex
J. Biol. Chem. 2006 281: 22752-22760. First Published on June 14, 2006; doi:10.1074/jbc.M601441200 [Abstract] [Full Text] [PDF]

Xiaoyan Ren, Debora A. Nicoll, and Kenneth D. Philipson: Helix Packing of the Cardiac Na⁺-Ca²⁺ Exchanger: PROXIMITY OF TRANSMEMBRANE SEGMENTS 1, 2, AND 6
J. Biol. Chem. 2006 281: 22808-22814. First Published on June 19, 2006; doi:10.1074/jbc.M604753200 [Abstract] [Full Text] [PDF]

Chris Meisinger, Nils Wiedemann, Michael Rissler, Andreas Strub, Dusanka Milenkovic, Birgit Schönfisch, Hanne Müller, Vera Kozjak, and Nikolaus Pfanner: Mitochondrial Protein Sorting: DIFFERENTIATION OF $beta$ -BARREL ASSEMBLY BY Tom7-MEDIATED SEGREGATION OF Mdm10
J. Biol. Chem. 2006 281: 22819-22826. First Published on June 7, 2006; doi:10.1074/jbc.M602679200 [Abstract] [Full Text] [PDF]

Yuki Miyauchi, Takashi Daiho, Kazuo Yamasaki, Hidetoshi Takahashi, Akemi Ishida-Yamamoto, Stefania Danko, Hiroshi Suzuki, and Hajime Iizuka: Comprehensive Analysis of Expression and Function of 51 Sarco(endo)plasmic Reticulum Ca²⁺-ATPase Mutants Associated with Darier Disease
J. Biol. Chem. 2006 281: 22882-22895. First Published on June 9, 2006; doi:10.1074/jbc.M601966200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Nakako Shibagaki and Arthur R. Grossman: The Role of the STAS Domain in the Function and Biogenesis of a Sulfate Transporter as Probed by Random Mutagenesis
J. Biol. Chem. 2006 281: 22964-22973. First Published on June 5, 2006; doi:10.1074/jbc.M603462200 [Abstract] [Full Text] [PDF]

Svetomir B. Tzokov, Neil R. Wyborn, Timothy J. Stillman, Stuart Jamieson, Nadine Czudnochowski, Peter J. Artymiuk, Jeffrey Green, and Per A. Bullough: Structure of the Hemolysin E (HlyE, ClyA, and SheA) Channel in Its Membrane-bound Form
J. Biol. Chem. 2006 281: 23042-23049. First Published on June 5, 2006; doi:10.1074/jbc.M602421200 [Abstract] [Full Text] [PDF]

Monica Agromayor and Juan Martin-Serrano: Interaction of AMSH with ESCRT-III and Deubiquitination of Endosomal Cargo
J. Biol. Chem. 2006 281: 23083-23091. First Published on June 7, 2006; doi:10.1074/jbc.M513803200 [Abstract] [Full Text] [PDF]

Shigeki Sugii, Song Lin, Nobutaka Ohgami, Masato Ohashi, Catherine C. Y. Chang, and Ta-Yuan Chang: Roles of Endogenously Synthesized Sterols in the Endocytic Pathway
J. Biol. Chem. 2006 281: 23191-23206. First Published on May 31, 2006; doi:10.1074/jbc.M603215200 [Abstract] [Full Text] [PDF]

Fei Liu, Fernando Terán Arce, Srinivasan Ramachandran, and Ratnesh Lal: Nanomechanics of Hemichannel Conformations: CONNEXIN FLEXIBILITY UNDERLYING CHANNEL OPENING AND CLOSING
J. Biol. Chem. 2006 281: 23207-23217. First Published on June 12, 2006; doi:10.1074/jbc.M605048200 [Abstract] [Full Text] [PDF]

Molecular Basis Of Cell and Developmental Biology:

Iordanes Karagiannides, Thomas Thomou, Tamara Tchkonia, Tamar Pirtskhalava, Kyriakos E. Kypreos, Andrew Cartwright, Georgia Dalagiorgou, Timothy L. Lash, Stephen R. Farmer, Nikolai A. Timchenko, and James L. Kirkland: Increased CUG Triplet Repeat-binding Protein-1 Predisposes to Impaired Adipogenesis with Aging
J. Biol. Chem. 2006 281: 23025-23033. First Published on June 5, 2006; doi:10.1074/jbc.M513187200 [Abstract] [Full Text] [PDF]

Mirjam Eckert, Sarah E. M. Meek, and Kathryn L. Ball: A Novel Repressor Domain Is Required for Maximal Growth Inhibition by the IRF-1 Tumor Suppressor
J. Biol. Chem. 2006 281: 23092-23102. First Published on May 4, 2006; doi:10.1074/jbc.M512589200 [Abstract] [Full Text] [PDF]

Baohong Zhao, Takenobu Katagiri, Hiromitsu Toyoda, Takatora Takada, Takako Yanai, Toru Fukuda, Ung-il Chung, Tatsuya Koike, Kunio Takaoka, and Ryutaro Kamijo: Heparin Potentiates the in Vivo Ectopic Bone Formation Induced by Bone Morphogenetic Protein-2
J. Biol. Chem. 2006 281: 23246-23253. First Published on June 5, 2006; doi:10.1074/jbc.M511039200 [Abstract] [Full Text] [PDF]

Mechanisms Of Signal Transduction:

Padma Kannan-Thulasiraman, Efstratios Katsoulidis, Martin S. Tallman, J. Simon C. Arthur, and Leonidas C. Platanias: Activation of the Mitogen- and Stress-activated Kinase 1 by Arsenic Trioxide
J. Biol. Chem. 2006 281: 22446-22452. First Published on June 8, 2006; doi:10.1074/jbc.M603111200 [Abstract] [Full Text] [PDF]

Benjamine J. Cooper, Brian Key, Adrian Carter, Nicola Z. Angel, Derek N. J. Hart, and Masato Kato: Suppression and Overexpression of Adenosylhomocysteine Hydrolase-like Protein 1 (AHCYL1) Influences Zebrafish Embryo Development: A POSSIBLE ROLE FOR AHCYL1 IN INOSITOL PHOSPHOLIPID SIGNALING
J. Biol. Chem. 2006 281: 22471-22484. First Published on June 5, 2006; doi:10.1074/jbc.M602520200 [Abstract] [Full Text] [PDF]

Tomiyasu Murata, Masaru Tsuboi, Kiyomi Hikita, and Norio Kaneda: Protective Effects of Neurotrophic Factors on Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL)-mediated Apoptosis of Murine Adrenal Chromaffin Cell Line tsAM5D
J. Biol. Chem. 2006 281: 22503-22516. First Published on June 13, 2006; doi:10.1074/jbc.M602579200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Masmudur M. Rahman, John W. Barrett, Peter Brouckaert, and Grant McFadden: Variation in Ligand Binding Specificities of a Novel Class of Poxvirus-encoded Tumor Necrosis Factor-binding Protein
J. Biol. Chem. 2006 281: 22517-22526. First Published on June 16, 2006; doi:10.1074/jbc.M604645200 [Abstract] [Full Text] [PDF] [Supplmental Data]

Rashna D. Balsara, Francis J. Castellino, and Victoria A. Ploplis: A Novel Function of Plasminogen Activator Inhibitor-1 in Modulation of the AKT Pathway in Wild-type and Plasminogen Activator Inhibitor-1-deficient Endothelial Cells
J. Biol. Chem. 2006 281: 22527-22536. First Published on June 19, 2006; doi:10.1074/jbc.M512819200 [Abstract] [Full Text] [PDF]

Tobias Warger, Nobert Hilf, Gerd Rechtsteiner, Philipp Haselmayer, Deanna M. Carrick, Helmut Jonuleit, Philipp von Landenberg, Hans-Georg Rammensee, Christopher V. Nicchitta, Markus P. Radsak, and Hansjörg Schild: Interaction of TLR2 and TLR4 Ligands with the N-terminal Domain of Gp96 Amplifies Innate and Adaptive Immune Responses
J. Biol. Chem. 2006 281: 22545-22553. First Published on June 5, 2006; doi:10.1074/jbc.M502900200 [Abstract] [Full Text] [PDF]

Cameron P. Bracken, Anthony O. Fedele, Sarah Linke, Wiltiana Balrak, Karolina Lisy, Murray L. Whitelaw, and Daniel J. Peet: Cell-specific Regulation of Hypoxia-inducible Factor (HIF)-1 ${alpha}$ and HIF-2 ${alpha}$ Stabilization and Transactivation in a Graded Oxygen Environment
J. Biol. Chem. 2006 281: 22575-22585. First Published on June 7, 2006; doi:10.1074/jbc.M600288200 [Abstract] [Full Text] [PDF]

Sergiy I. Borysov, Anthony W. M. Cheng, and Thomas M. Guadagno: B-Raf Is Critical For MAPK Activation during Mitosis and Is Regulated in an M Phase-dependent Manner in Xenopus Egg Extracts
J. Biol. Chem. 2006 281: 22586-22596. First Published on June 8, 2006; doi:10.1074/jbc.M601432200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Biserka Relic, Valérie Benoit, Nathalie Franchimont, Marie-Joelle Kaiser, Jean-Philippe Hauzeur, Philippe Gillet, Marie-Paule Merville, Vincent Bours, and Michel G. Malaise: Peroxisome Proliferator-activated Receptor- ${gamma}$ 1 Is Dephosphorylated and Degraded during BAY 11-7085-induced Synovial Fibroblast Apoptosis
J. Biol. Chem. 2006 281: 22597-22604. First Published on June 9, 2006; doi:10.1074/jbc.M512807200 [Abstract] [Full Text] [PDF]

Vera Carolina B. Bittencourt, Rodrigo T. Figueiredo, Rosana B. da Silva, Diego S. Mourão-Sá, Patricia L. Fernandez, Guilherme L. Sassaki, Barbara Mulloy, Marcelo T. Bozza, and Eliana Barreto-Bergter: An ${alpha}$ -Glucan of Pseudallescheria boydii Is Involved in Fungal Phagocytosis and Toll-like Receptor Activation
J. Biol. Chem. 2006 281: 22614-22623. First Published on June 9, 2006; doi:10.1074/jbc.M511417200 [Abstract] [Full Text] [PDF]

Bjarki Stefansson and David L. Brautigan: Protein Phosphatase 6 Subunit with Conserved Sit4-associated Protein Domain Targets I ${kappa}$ B ${epsilon}$
J. Biol. Chem. 2006 281: 22624-22634. First Published on June 12, 2006; doi:10.1074/jbc.M601772200 [Abstract] [Full Text] [PDF]

Juana M. García-Pedrero, Evangelos Kiskinis, Malcolm G. Parker, and Borja Belandia: The SWI/SNF Chromatin Remodeling Subunit BAF57 Is a Critical Regulator of Estrogen Receptor Function in Breast Cancer Cells
J. Biol. Chem. 2006 281: 22656-22664. First Published on June 12, 2006; doi:10.1074/jbc.M602561200 [Abstract] [Full Text] [PDF]

Nafeesa A. Noordeen, Federico Carafoli, Erhard Hohenester, Michael A. Horton, and Birgit Leitinger: A Transmembrane Leucine Zipper Is Required for Activation of the Dimeric Receptor Tyrosine Kinase DDR1
J. Biol. Chem. 2006 281: 22744-22751. First Published on June 14, 2006; doi:10.1074/jbc.M603233200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Dongmei Lu, Jie Huang, and Alakananda Basu: Protein Kinase C ${epsilon}$ Activates Protein Kinase B/Akt via DNA-PK to Protect against Tumor Necrosis Factor- ${alpha}$ -induced Cell Death
J. Biol. Chem. 2006 281: 22799-22807. First Published on June 19, 2006; doi:10.1074/jbc.M603390200 [Abstract] [Full Text] [PDF]

Makoto Arita, Sungwhan F. Oh, Tomomichi Chonan, Song Hong, Siva Elangovan, Yee-Ping Sun, Jasim Uddin, Nicos A. Petasis, and Charles N. Serhan: Metabolic Inactivation of Resolvin E1 and Stabilization of Its Anti-inflammatory Actions
J. Biol. Chem. 2006 281: 22847-22854. First Published on June 6, 2006; doi:10.1074/jbc.M603766200 [Abstract] [Full Text] [PDF]

Edward F. Rocnik, Peijun Liu, Kaori Sato, Kenneth Walsh, and Cyrus Vaziri: The Novel SPARC Family Member SMOC-2 Potentiates Angiogenic Growth Factor Activity
J. Biol. Chem. 2006 281: 22855-22864. First Published on June 14, 2006; doi:10.1074/jbc.M513463200 [Abstract] [Full Text] [PDF]

Núria Bahi, Jisheng Zhang, Marta Llovera, Manel Ballester, Joan X. Comella, and Daniel Sanchis: Switch from Caspase-dependent to Caspase-independent Death during Heart Development: ESSENTIAL ROLE OF ENDONUCLEASE G IN ISCHEMIA-INDUCED DNA PROCESSING OF DIFFERENTIATED CARDIOMYOCYTES
J. Biol. Chem. 2006 281: 22943-22952. First Published on June 5, 2006; doi:10.1074/jbc.M601025200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Tania Fiaschi, Giacomo Cozzi, Giovanni Raugei, Lucia Formigli, Giampietro Ramponi, and Paola Chiarugi: Redox Regulation of $beta$ -Actin during Integrin-mediated Cell Adhesion
J. Biol. Chem. 2006 281: 22983-22991. First Published on June 5, 2006; doi:10.1074/jbc.M603040200 [Abstract] [Full Text] [PDF]

Seiko F. Okada, Robert A. Nicholas, Silvia M. Kreda, Eduardo R. Lazarowski, and Richard C. Boucher: Physiological Regulation of ATP Release at the Apical Surface of Human Airway Epithelia
J. Biol. Chem. 2006 281: 22992-23002. First Published on June 5, 2006; doi:10.1074/jbc.M603019200 [Abstract] [Full Text] [PDF] [Summary]

Roland Reinehr, Stephan Becker, Juliane Braun, Andrea Eberle, Susanne Grether-Beck, and Dieter Haüssinger: Endosomal Acidification and Activation of NADPH Oxidase Isoforms Are Upstream Events in Hyperosmolarity-induced Hepatocyte Apoptosis
J. Biol. Chem. 2006 281: 23150-23166. First Published on June 13, 2006; doi:10.1074/jbc.M601451200 [Abstract] [Full Text] [PDF] [Supplemental data]

Viktoria Kheifets, Rachel Bright, Koichi Inagaki, Deborah Schechtman, and Daria Mochly-Rosen: Protein Kinase C ${delta}$ ( ${delta}$ PKC)-Annexin V Interaction: A REQUIRED STEP IN ${delta}$ PKC TRANSLOCATION AND FUNCTION
J. Biol. Chem. 2006 281: 23218-23226. First Published on June 18, 2006; doi:10.1074/jbc.M602075200 [Abstract] [Full Text] [PDF]

Marie Dance, Alexandra Montagner, Armelle Yart, Bernard Masri, Yves Audigier, Bertrand Perret, Jean-Pierre Salles, and Patrick Raynal: The Adaptor Protein Gab1 Couples the Stimulation of Vascular Endothelial Growth Factor Receptor-2 to the Activation of Phosphoinositide 3-Kinase
J. Biol. Chem. 2006 281: 23285-23295. First Published on June 20, 2006; doi:10.1074/jbc.M600987200 [Abstract] [Full Text] [PDF]

Additions and Corrections:

Penny J. Beuning, Sharotka M. Simon, Adam Zemla, Daniel Barsky, and Graham C. Walker: A non-cleavable UmuD variant that acts as a UmuD' mimic. VOLUME 281 (2006) PAGES 9633-9640
J. Biol. Chem. 2006 281: 23296. [Full Text] [PDF]

Melissa K. Lingohr, Isabelle Briaud, Lorna M. Dickson, Jill F. McCuaig, Cristina Alarcón, Barton L. Wicksteed, and Christopher J. Rhodes: Specific regulation of IRS-2 expression by glucose in rat primary pancreatic islet $beta$ -cells. VOLUME 281 (2006) PAGES 15884-15892
J. Biol. Chem. 2006 281: 23296-a. [Full Text] [PDF]