On The Cover: Specific proteolysis is commonly regulated by target attachment to ubiquitin C-terminal glycine 76. Structurally related, the membrane-anchored ubiquitin-fold proteins (MUBs) depicted here are likely to play different roles because the C termini are modified with hydrophobic prenyl groups (white) that frequently associate with plasma membrane (PM, gray). Confocal microscopy of an Arabidopsis thaliana protoplast transformed with GFP-AtMUB reveals PM localization (green) and autofluorescent chloroplasts (red). For details see the article by Downes et al., pages 27145–27157.
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