JBC -- Table of Contents (Dec 8 2006, 281, (49))

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Classics:

Nicole Kresge, Robert D. Simoni, and Robert L. Hill: Acetyl-CoA Carboxylase and Other Biotin-dependent Enzymes: the Work of M. Daniel Lane
The Enzymatic Synthesis of Holotranscarboxylase from Apotranscarboxylase and (+)-Biotin. II. INVESTIGATION OF THE REACTION MECHANISM (M. Daniel Lane, K. L. Rominger, David L. Young, and F. Lynen J. Biol. Chem. 239, 2865-2871)
Liver Acetyl Coenzyme A Carboxylase. II. FURTHER MOLECULAR CHARACTERIZATION (Carlo Gregolin, Elena Ryder, Robert C. Warner, Albrecht K. Kleinschmidt, Huei-Che Chang, and M. Daniel Lane J. Biol. Chem. 243, 4236-4245)
Acetyl Coenzyme A Carboxylase System of Escherichia coli. SITE OF CARBOXYLATION OF BIOTIN AND ENZYMATIC REACTIVITY OF 1'-N-(UREIDO)-CARBOXYBIOTIN DERIVATIVES (Ras B. Guchhait, S. Efthimios Polakis, Donald Hollis, Catherine Fenselau, and M. Daniel Lane J. Biol. Chem. 249, 6646-6656)
Acetyl Coenzyme A Carboxylase System of Escherichia coli. STUDIES ON THE MECHANISMS OF THE BIOTIN CARBOXYLASE- AND CARBOXYLTRANSFERASE-CATALYZED REACTIONS (S. Efthimios Polakis, Ras B. Guchhait, Eberhard E. Zwergel, M. Daniel Lane, and Terrance G. Cooper J. Biol. Chem. 249, 6657-6667)
J. Biol. Chem. 2006 281: e40. [Full Text]

Minireviews:

Michael J. Wolfgang and M. Daniel Lane: The Role of Hypothalamic Malonyl-CoA in Energy Homeostasis
J. Biol. Chem. 2006 281: 37265-37269. First Published on October 3, 2006; doi:10.1074/jbc.R600016200 [Abstract] [Full Text] [PDF]

Accelerated Publications:

Jessica Schneider, Pratibha Bajwa, Farley C. Johnson, Sukesh R. Bhaumik, and Ali Shilatifard: Rtt109 Is Required for Proper H3K56 Acetylation: A CHROMATIN MARK ASSOCIATED WITH THE ELONGATING RNA POLYMERASE II
J. Biol. Chem. 2006 281: 37270-37274. First Published on October 17, 2006; doi:10.1074/jbc.C600265200 [Abstract] [Full Text] [PDF]

DNA: Replication, Repair, and Recombination:

Itay Onn, Irit Kapeller, Kawther Abu-Elneel, and Joseph Shlomai: Binding of the Universal Minicircle Sequence Binding Protein at the Kinetoplast DNA Replication Origin
J. Biol. Chem. 2006 281: 37468-37476. First Published on October 16, 2006; doi:10.1074/jbc.M606374200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Nicole Fouché, Anthony J. Cesare, Smaranda Willcox, Sezgin Özgür, Sarah A. Compton, and Jack D. Griffith: The Basic Domain of TRF2 Directs Binding to DNA Junctions Irrespective of the Presence of TTAGGG Repeats
J. Biol. Chem. 2006 281: 37486-37495. First Published on October 18, 2006; doi:10.1074/jbc.M608778200 [Abstract] [Full Text] [PDF]

Pierre Hentges, Peter Ahnesorg, Robert S. Pitcher, Chris K. Bruce, Boris Kysela, Andrew J. Green, Julie Bianchi, Thomas E. Wilson, Stephen P. Jackson, and Aidan J. Doherty: Evolutionary and Functional Conservation of the DNA Non-homologous End-joining Protein, XLF/Cernunnos
J. Biol. Chem. 2006 281: 37517-37526. First Published on October 12, 2006; doi:10.1074/jbc.M608727200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Young Hwang, Nana Minkah, Kay Perry, Gregory D. Van Duyne, and Frederic D. Bushman: Regulation of Catalysis by the Smallpox Virus Topoisomerase
J. Biol. Chem. 2006 281: 38052-38060. First Published on October 10, 2006; doi:10.1074/jbc.M608858200 [Abstract] [Full Text] [PDF] [TopoMutants8cleav.pdf][Supplemental Data]

Genes: Structure and Regulation:

Melissa L. Martowicz, Jeffrey A. Grass, and Emery H. Bresnick: GATA-1-mediated Transcriptional Repression Yields Persistent Transcription Factor IIB-Chromatin Complexes
J. Biol. Chem. 2006 281: 37345-37352. First Published on September 8, 2006; doi:10.1074/jbc.M605774200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Hiroki Sekine, Junsei Mimura, Masayuki Yamamoto, and Yoshiaki Fujii-Kuriyama: Unique and Overlapping Transcriptional Roles of Arylhydrocarbon Receptor Nuclear Translocator (Arnt) and Arnt2 in Xenobiotic and Hypoxic Responses
J. Biol. Chem. 2006 281: 37507-37516. First Published on October 5, 2006; doi:10.1074/jbc.M606910200 [Abstract] [Full Text] [PDF]

David L. Woodhall, Ian J. Groves, Matthew B. Reeves, Gavin Wilkinson, and John H. Sinclair: Human Daxx-mediated Repression of Human Cytomegalovirus Gene Expression Correlates with a Repressive Chromatin Structure around the Major Immediate Early Promoter
J. Biol. Chem. 2006 281: 37652-37660. First Published on October 11, 2006; doi:10.1074/jbc.M604273200 [Abstract] [Full Text] [PDF]

Liping Wang, William J. Zuercher, Thomas G. Consler, Millard H. Lambert, Aaron B. Miller, Lisa A. Orband-Miller, David D. McKee, Timothy M. Willson, and Robert T. Nolte: X-ray Crystal Structures of the Estrogen-related Receptor- ${gamma}$ Ligand Binding Domain in Three Functional States Reveal the Molecular Basis of Small Molecule Regulation
J. Biol. Chem. 2006 281: 37773-37781. First Published on September 21, 2006; doi:10.1074/jbc.M608410200 [Abstract] [Full Text] [PDF]

Kirsten Mattison, J. Scott Wilbur, Magdalene So, and Richard G. Brennan: Structure of FitAB from Neisseria gonorrhoeae Bound to DNA Reveals a Tetramer of Toxin-Antitoxin Heterodimers Containing Pin Domains and Ribbon-Helix-Helix Motifs
J. Biol. Chem. 2006 281: 37942-37951. First Published on September 18, 2006; doi:10.1074/jbc.M605198200 [Abstract] [Full Text] [PDF]

RNA: Structure, Metabolism, and Catalysis:

Janine Kraunus, Daniela Zychlinski, Tilman Heise, Melanie Galla, Jens Bohne, and Christopher Baum: Murine Leukemia Virus Regulates Alternative Splicing through Sequences Upstream of the 5· Splice Site
J. Biol. Chem. 2006 281: 37381-37390. First Published on October 11, 2006; doi:10.1074/jbc.M601537200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Kenji Okuda, Takahiro Nakamura, Mamoru Sugita, Toshiyuki Shimizu, and Toshiharu Shikanai: A Pentatricopeptide Repeat Protein Is a Site Recognition Factor in Chloroplast RNA Editing
J. Biol. Chem. 2006 281: 37661-37667. First Published on October 2, 2006; doi:10.1074/jbc.M608184200 [Abstract] [Full Text] [PDF] [Summary]

Cristina Gherghe and Kevin M. Weeks: The SL1-SL2 (Stem-Loop) Domain Is the Primary Determinant for Stability of the Gamma Retroviral Genomic RNA Dimer
J. Biol. Chem. 2006 281: 37952-37961. First Published on September 19, 2006; doi:10.1074/jbc.M607380200 [Abstract] [Full Text] [PDF]

Protein Synthesis, Post-Translation Modification, and Degradation:

Ilaria Dragoni, Elizabeth Guida, and Peter McIntyre: The Cold and Menthol Receptor TRPM8 Contains a Functionally Important Double Cysteine Motif
J. Biol. Chem. 2006 281: 37353-37360. First Published on October 2, 2006; doi:10.1074/jbc.M607227200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Susan S. Ishmael, Faoud T. Ishmael, A. Daniel Jones, and Judith S. Bond: Protease Domain Glycans Affect Oligomerization, Disulfide Bond Formation, and Stability of the Meprin A Metalloprotease Homo-oligomer
J. Biol. Chem. 2006 281: 37404-37415. First Published on October 13, 2006; doi:10.1074/jbc.M602769200 [Abstract] [Full Text] [PDF]

Motoo Suzuki, Rohini Roy, Haiyan Zheng, Nancy Woychik, and Masayori Inouye: Bacterial Bioreactors for High Yield Production of Recombinant Protein
J. Biol. Chem. 2006 281: 37559-37565. First Published on October 4, 2006; doi:10.1074/jbc.M608806200 [Abstract] [Full Text] [PDF]

Yoshitake Sano, Aiko Syuzo-Takabatake, Tadashi Nakaya, Yuhki Saito, Susumu Tomita, Shigeyoshi Itohara, and Toshiharu Suzuki: Enhanced Amyloidogenic Metabolism of the Amyloid $beta$ -Protein Precursor in the X11L-deficient Mouse Brain
J. Biol. Chem. 2006 281: 37853-37860. First Published on October 10, 2006; doi:10.1074/jbc.M609312200 [Abstract] [Full Text] [PDF] [SupplM6-09312.pdf]

Adam J. Hoffhines, Eugen Damoc, Kristie G. Bridges, Julie A. Leary, and Kevin L. Moore: Detection and Purification of Tyrosine-sulfated Proteins Using a Novel Anti-sulfotyrosine Monoclonal Antibody
J. Biol. Chem. 2006 281: 37877-37887. First Published on October 17, 2006; doi:10.1074/jbc.M609398200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Shih-Ching Lo and Mark Hannink: PGAM5, a Bcl-X_L-interacting Protein, Is a Novel Substrate for the Redox-regulated Keap1-dependent Ubiquitin Ligase Complex
J. Biol. Chem. 2006 281: 37893-37903. First Published on October 17, 2006; doi:10.1074/jbc.M606539200 [Abstract] [Full Text] [PDF]

Helen Rizos, Heather A. McKenzie, Ana Luisa Ayub, Sarah Woodruff, Therese M. Becker, Lyndee L. Scurr, Joachim Stahl, and Richard F. Kefford: Physical and Functional Interaction of the p14^ARF Tumor Suppressor with Ribosomes
J. Biol. Chem. 2006 281: 38080-38088. First Published on October 11, 2006; doi:10.1074/jbc.M609405200 [Abstract] [Full Text] [PDF]

Protein Structure and Folding:

Oliver H. Weiergräber, Ivan I. Senin, Eugene Yu Zernii, Valeriya A. Churumova, Nadezhda A. Kovaleva, Aliya A. Nazipova, Sergei E. Permyakov, Eugene A. Permyakov, Pavel P. Philippov, Joachim Granzin, and Karl-Wilhelm Koch: Tuning of a Neuronal Calcium Sensor
J. Biol. Chem. 2006 281: 37594-37602. First Published on October 2, 2006; doi:10.1074/jbc.M603700200 [Abstract] [Full Text] [PDF]

Marco Nardini, Alessandra Pesce, Marie Labarre, Christian Richard, Alessandro Bolli, Paolo Ascenzi, Michel Guertin, and Martino Bolognesi: Structural Determinants in the Group III Truncated Hemoglobin from Campylobacter jejuni
J. Biol. Chem. 2006 281: 37803-37812. First Published on October 5, 2006; doi:10.1074/jbc.M607254200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Mitchell C. Y. Chan, Satoshi Karasawa, Hideaki Mizuno, Ivan Bosanac, Dona Ho, Gilbert G. Privé, Atsushi Miyawaki, and Mitsuhiko Ikura: Structural Characterization of a Blue Chromoprotein and Its Yellow Mutant from the Sea Anemone Cnidopus Japonicus
J. Biol. Chem. 2006 281: 37813-37819. First Published on October 6, 2006; doi:10.1074/jbc.M606921200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Martin Margittai and Ralf Langen: Side Chain-dependent Stacking Modulates Tau Filament Structure
J. Biol. Chem. 2006 281: 37820-37827. First Published on October 5, 2006; doi:10.1074/jbc.M605336200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Rosa Grenha, Neil J. Rzechorzek, James A. Brannigan, Rob N. de Jong, Eiso AB, Tammo Diercks, Vincent Truffault, Joanne C. Ladds, Mark J. Fogg, Cristina Bongiorni, Marta Perego, Robert Kaptein, Keith S. Wilson, Gert E. Folkers, and Anthony J. Wilkinson: Structural Characterization of Spo0E-like Protein-aspartic Acid Phosphatases That Regulate Sporulation in Bacilli
J. Biol. Chem. 2006 281: 37993-38003. First Published on September 25, 2006; doi:10.1074/jbc.M607617200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Paul J. Ala, Lucie Gonneville, Milton Hillman, Mary Becker-Pasha, Eddy W. Yue, Brent Douty, Brian Wayland, Padmaja Polam, Matthew L. Crawley, Erin McLaughlin, Richard B. Sparks, Brian Glass, Amy Takvorian, Andrew P. Combs, Timothy C. Burn, Gregory F. Hollis, and Richard Wynn: Structural Insights into the Design of Nonpeptidic Isothiazolidinone-containing Inhibitors of Protein-tyrosine Phosphatase 1B
J. Biol. Chem. 2006 281: 38013-38021. First Published on October 6, 2006; doi:10.1074/jbc.M607913200 [Abstract] [Full Text] [PDF]

George V. Avvakumov, John R. Walker, Sheng Xue, Patrick J. Finerty, Jr., Farrell Mackenzie, Elena M. Newman, and Sirano Dhe-Paganon: Amino-terminal Dimerization, NRDP1-Rhodanese Interaction, and Inhibited Catalytic Domain Conformation of the Ubiquitin-specific Protease 8 (USP8)
J. Biol. Chem. 2006 281: 38061-38070. First Published on October 11, 2006; doi:10.1074/jbc.M606704200 [Abstract] [Full Text] [PDF] [jbcsup.pdf]

William Holmes and Gerwald Jogl: Crystal Structure of Inositol Phosphate Multikinase 2 and Implications for Substrate Specificity
J. Biol. Chem. 2006 281: 38109-38116. First Published on October 18, 2006; doi:10.1074/jbc.M606883200 [Abstract] [Full Text] [PDF]

Enzyme Catalysis and Regulation:

Thorsten Hornemann, Stephane Richard, Markus F. Rütti, Yu Wei, and Arnold von Eckardstein: Cloning and Initial Characterization of a New Subunit for Mammalian Serine-palmitoyltransferase
J. Biol. Chem. 2006 281: 37275-37281. First Published on October 4, 2006; doi:10.1074/jbc.M608066200 [Abstract] [Full Text] [PDF]

Taketoshi Kambara, Shigeru Komaba, and Mitsuo Ikebe: Human Myosin III Is a Motor Having an Extremely High Affinity for Actin
J. Biol. Chem. 2006 281: 37291-37301. First Published on October 1, 2006; doi:10.1074/jbc.M603823200 [Abstract] [Full Text] [PDF]

Rafal Jonczyk and Ulrich Genschel: Molecular Adaptation and Allostery in Plant Pantothenate Synthetases
J. Biol. Chem. 2006 281: 37435-37446. First Published on October 13, 2006; doi:10.1074/jbc.M607895200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Colin A. Kretz, Alan R. Stafford, James C. Fredenburgh, and Jeffrey I. Weitz: HD1, a Thrombin-directed Aptamer, Binds Exosite 1 on Prothrombin with High Affinity and Inhibits Its Activation by Prothrombinase
J. Biol. Chem. 2006 281: 37477-37485. First Published on October 17, 2006; doi:10.1074/jbc.M607359200 [Abstract] [Full Text] [PDF]

Nagayasu Egawa, Naohiko Koshikawa, Taizo Tomari, Kazuki Nabeshima, Toshiaki Isobe, and Motoharu Seiki: Membrane Type 1 Matrix Metalloproteinase (MT1-MMP/MMP-14) Cleaves and Releases a 22-kDa Extracellular Matrix Metalloproteinase Inducer (EMMPRIN) Fragment from Tumor Cells
J. Biol. Chem. 2006 281: 37576-37585. First Published on October 18, 2006; doi:10.1074/jbc.M606993200 [Abstract] [Full Text] [PDF]

Basma El Yacoubi, Shilah Bonnett, Jessica N. Anderson, Manal A. Swairjo, Dirk Iwata-Reuyl, and Valérie de Crécy-Lagard: Discovery of a New Prokaryotic Type I GTP Cyclohydrolase Family
J. Biol. Chem. 2006 281: 37586-37593. First Published on October 10, 2006; doi:10.1074/jbc.M607114200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Mayumi Futamura, Hideka Hosaka, Akito Kadotani, Hiroko Shimazaki, Kaori Sasaki, Sumika Ohyama, Teruyuki Nishimura, Jun-ichi Eiki, and Yasufumi Nagata: An Allosteric Activator of Glucokinase Impairs the Interaction of Glucokinase and Glucokinase Regulatory Protein and Regulates Glucose Metabolism
J. Biol. Chem. 2006 281: 37668-37674. First Published on October 6, 2006; doi:10.1074/jbc.M605186200 [Abstract] [Full Text] [PDF]

Sarah Adio, Marieke Bloemink, Michaela Hartel, Sven Leier, Michael A. Geeves, and Günther Woehlke: Kinetic and Mechanistic Basis of the Nonprocessive Kinesin-3 Motor NcKin3
J. Biol. Chem. 2006 281: 37782-37793. First Published on October 1, 2006; doi:10.1074/jbc.M605061200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Erumbi S. Rangarajan, Ariane Proteau, John Wagner, Ming-Ni Hung, Allan Matte, and Miroslaw Cygler: Structural Snapshots of Escherichia coli Histidinol Phosphate Phosphatase along the Reaction Pathway
J. Biol. Chem. 2006 281: 37930-37941. First Published on September 11, 2006; doi:10.1074/jbc.M604916200 [Abstract] [Full Text] [PDF]

Scot A. Lieser, Jennifer Shaffer, and Joseph A. Adams: Src Tail Phosphorylation Is Limited by Structural Changes in the Regulatory Tyrosine Kinase Csk
J. Biol. Chem. 2006 281: 38004-38012. First Published on October 3, 2006; doi:10.1074/jbc.M607824200 [Abstract] [Full Text] [PDF]

Metabolism and Bioenergetics:

Laudiene Evangelista Meyer, Lilia Bender Machado, Ana Paula S. A. Santiago, Wagner Seixas da-Silva, Fernanda G. De Felice, Oliver Holub, Marcus F. Oliveira, and Antonio Galina: Mitochondrial Creatine Kinase Activity Prevents Reactive Oxygen Species Generation: ANTIOXIDANT ROLE OF MITOCHONDRIAL KINASE-DEPENDENT ADP RE-CYCLING ACTIVITY
J. Biol. Chem. 2006 281: 37361-37371. First Published on October 6, 2006; doi:10.1074/jbc.M604123200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Natalia Shalbuyeva, Tatiana Brustovetsky, Alexey Bolshakov, and Nickolay Brustovetsky: Calcium-dependent Spontaneously Reversible Remodeling of Brain Mitochondria
J. Biol. Chem. 2006 281: 37547-37558. First Published on October 19, 2006; doi:10.1074/jbc.M607263200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Glycobiology and Extracellular Matrices:

Jae-Eun Lee and Youngho Kim: A Tissue-specific Variant of the Human Lysyl Oxidase-like Protein 3 (LOXL3) Functions as an Amine Oxidase with Substrate Specificity
J. Biol. Chem. 2006 281: 37282-37290. First Published on October 3, 2006; doi:10.1074/jbc.M600977200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Elizabeth Ficko-Blean and Alisdair B. Boraston: The Interaction of a Carbohydrate-binding Module from a Clostridium perfringens N-Acetyl- $beta$ -hexosaminidase with Its Carbohydrate Receptor
J. Biol. Chem. 2006 281: 37748-37757. First Published on September 21, 2006; doi:10.1074/jbc.M606126200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Andrew C. Lake, Roger Vassy, Mélanie Di Benedetto, Damien Lavigne, Catherine Le Visage, Gérard Y. Perret, and Didier Letourneur: Low Molecular Weight Fucoidan Increases VEGF₁₆₅-induced Endothelial Cell Migration by Enhancing VEGF₁₆₅ Binding to VEGFR-2 and NRP1
J. Biol. Chem. 2006 281: 37844-37852. First Published on October 6, 2006; doi:10.1074/jbc.M600686200 [Abstract] [Full Text] [PDF]

Shizuyo Tsujimura, Kazuyoshi Saito, Kimitoshi Kohno, and Yoshiya Tanaka: Fragmented Hyaluronan Induces Transcriptional Up-regulation of the Multidrug Resistance-1 Gene in CD4+ T Cells
J. Biol. Chem. 2006 281: 38089-38097. First Published on October 12, 2006; doi:10.1074/jbc.M601030200 [Abstract] [Full Text] [PDF]

Lipids and Lipoproteins:

Takao Kimura, Hideaki Tomura, Chihiro Mogi, Atsushi Kuwabara, Alatangaole Damirin, Tamotsu Ishizuka, Akihiro Sekiguchi, Mitsuteru Ishiwara, Doon-Soon Im, Koichi Sato, Masami Murakami, and Fumikazu Okajima: Role of Scavenger Receptor Class B Type I and Sphingosine 1-Phosphate Receptors in High Density Lipoprotein-induced Inhibition of Adhesion Molecule Expression in Endothelial Cells
J. Biol. Chem. 2006 281: 37457-37467. First Published on October 16, 2006; doi:10.1074/jbc.M605823200 [Abstract] [Full Text] [PDF]

Yuan-Li Zhang, Antonio Hernandez-Ono, Patty Siri, Stuart Weisberg, Donna Conlon, Mark J. Graham, Rosanne M. Crooke, Li-Shin Huang, and Henry N. Ginsberg: Aberrant Hepatic Expression of PPAR ${gamma}$ 2 Stimulates Hepatic Lipogenesis in a Mouse Model of Obesity, Insulin Resistance, Dyslipidemia, and Hepatic Steatosis
J. Biol. Chem. 2006 281: 37603-37615. First Published on September 12, 2006; doi:10.1074/jbc.M604709200 [Abstract] [Full Text] [PDF]

Jacques Robidoux, Naresh Kumar, Kiefer W. Daniel, Fatiha Moukdar, Michel Cyr, Alexander V. Medvedev, and Sheila Collins: Maximal $beta$ ₃-Adrenergic Regulation of Lipolysis Involves Src and Epidermal Growth Factor Receptor-dependent ERK1/2 Activation
J. Biol. Chem. 2006 281: 37794-37802. First Published on October 10, 2006; doi:10.1074/jbc.M605572200 [Abstract] [Full Text] [PDF]

Membrane Transport, Structure, Function, and Biogenesis:

Tatiana K. Rostovtseva, Namdar Kazemi, Michael Weinrich, and Sergey M. Bezrukov: Voltage Gating of VDAC Is Regulated by Nonlamellar Lipids of Mitochondrial Membranes
J. Biol. Chem. 2006 281: 37496-37506. First Published on September 21, 2006; doi:10.1074/jbc.M602548200 [Abstract] [Full Text] [PDF]

Qiang Li, Nicolás Montalbetti, Yuliang Wu, Arnolt Ramos, Malay K. Raychowdhury, Xing-Zhen Chen, and Horacio F. Cantiello: Polycystin-2 Cation Channel Function Is under the Control of Microtubular Structures in Primary Cilia of Renal Epithelial Cells
J. Biol. Chem. 2006 281: 37566-37575. First Published on September 1, 2006; doi:10.1074/jbc.M603643200 [Abstract] [Full Text] [PDF]

Olga Draper, Rebecca Middleton, Michaeleen Doucleff, and Patricia C. Zambryski: Topology of the VirB4 C Terminus in the Agrobacterium tumefaciens VirB/D4 Type IV Secretion System
J. Biol. Chem. 2006 281: 37628-37635. First Published on October 12, 2006; doi:10.1074/jbc.M606403200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Rubén Vicente, Artur Escalada, Nuria Villalonga, Laura Texidó, Meritxell Roura-Ferrer, Mireia Martín-Satué, Carmen López-Iglesias, Concepció Soler, Carles Solsona, Michael M. Tamkun, and Antonio Felipe: Association of Kv1.5 and Kv1.3 Contributes to the Major Voltage-dependent K⁺ Channel in Macrophages
J. Biol. Chem. 2006 281: 37675-37685. First Published on October 11, 2006; doi:10.1074/jbc.M605617200 [Abstract] [Full Text] [PDF]

Akiko Maeda, Tadao Maeda, Yoshikazu Imanishi, Wenyu Sun, Beata Jastrzebska, Denise A. Hatala, Huub J. Winkens, Klaus Peter Hofmann, Jacques J. Janssen, Wolfgang Baehr, Carola A. Driessen, and Krzysztof Palczewski: Retinol Dehydrogenase (RDH12) Protects Photoreceptors from Light-induced Degeneration in Mice
J. Biol. Chem. 2006 281: 37697-37704. First Published on October 10, 2006; doi:10.1074/jbc.M608375200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Francesco Tadini-Buoninsegni, Gianluca Bartolommei, Maria Rosa Moncelli, Rolando Guidelli, and Giuseppe Inesi: Pre-steady State Electrogenic Events of Ca²⁺/H⁺ Exchange and Transport by the Ca²⁺-ATPase
J. Biol. Chem. 2006 281: 37720-37727. First Published on October 10, 2006; doi:10.1074/jbc.M606040200 [Abstract] [Full Text] [PDF]

Brian E. Schwem and Robert H. Fillingame: Cross-linking between Helices within Subunit a of Escherichia coli ATP Synthase Defines the Transmembrane Packing of a Four-helix Bundle
J. Biol. Chem. 2006 281: 37861-37867. First Published on October 11, 2006; doi:10.1074/jbc.M607453200 [Abstract] [Full Text] [PDF]

Gérald Gaibelet, Thierry Planchenault, Serge Mazères, Fabrice Dumas, Fernando Arenzana-Seisdedos, André Lopez, Bernard Lagane, and Françoise Bachelerie: CD4 and CCR5 Constitutively Interact at the Plasma Membrane of Living Cells: A CONFOCAL FLUORESCENCE RESONANCE ENERGY TRANSFER-BASED APPROACH
J. Biol. Chem. 2006 281: 37921-37929. First Published on October 11, 2006; doi:10.1074/jbc.M607103200 [Abstract] [Full Text] [PDF] [M607103supplementary.pdf]

Clifford W. Schweinfest, Demetri D. Spyropoulos, Kelly W. Henderson, Jae-Ho Kim, Jeannie M. Chapman, Sharon Barone, Roger T. Worrell, Zhaohui Wang, and Manoocher Soleimani: slc26a3 (dra)-deficient Mice Display Chloride-losing Diarrhea, Enhanced Colonic Proliferation, and Distinct Up-regulation of Ion Transporters in the Colon
J. Biol. Chem. 2006 281: 37962-37971. First Published on September 25, 2006; doi:10.1074/jbc.M607527200 [Abstract] [Full Text] [PDF]

Stéphane Duvezin-Caubet, Ravi Jagasia, Johannes Wagener, Sabine Hofmann, Aleksandra Trifunovic, Anna Hansson, Anne Chomyn, Matthias F. Bauer, Giuseppe Attardi, Nils-Göran Larsson, Walter Neupert, and Andreas S. Reichert: Proteolytic Processing of OPA1 Links Mitochondrial Dysfunction to Alterations in Mitochondrial Morphology
J. Biol. Chem. 2006 281: 37972-37979. First Published on September 26, 2006; doi:10.1074/jbc.M606059200 [Abstract] [Full Text] [PDF]

Maïté Courel, Carrie Rodemer, Susan T. Nguyen, Alena Pance, Antony P. Jackson, Daniel T. O'Connor, and Laurent Taupenot: Secretory Granule Biogenesis in Sympathoadrenal Cells: IDENTIFICATION OF A GRANULOGENIC DETERMINANT IN THE SECRETORY PROHORMONE CHROMOGRANIN A
J. Biol. Chem. 2006 281: 38038-38051. First Published on October 10, 2006; doi:10.1074/jbc.M604037200 [Abstract] [Full Text] [PDF]

Jennifer L. Perry, Neetu Dembla-Rajpal, Laura A. Hall, and John B. Pritchard: A Three-dimensional Model of Human Organic Anion Transporter 1: AROMATIC AMINO ACIDS REQUIRED FOR SUBSTRATE TRANSPORT
J. Biol. Chem. 2006 281: 38071-38079. First Published on October 11, 2006; doi:10.1074/jbc.M608834200 [Abstract] [Full Text] [PDF]

Molecular Basis Of Cell and Developmental Biology:

Satoru Mukai and Yukio Fujiki: Molecular Mechanisms of Import of Peroxisome-targeting Signal Type 2 (PTS2) Proteins by PTS2 Receptor Pex7p and PTS1 Receptor Pex5pL
J. Biol. Chem. 2006 281: 37311-37320. First Published on October 13, 2006; doi:10.1074/jbc.M607178200 [Abstract] [Full Text] [PDF]

Rushika Sumathipala, Cunshuan Xu, Julian Seago, A. Paul Mould, Martin J. Humphries, Sue E. Craig, Yatin Patel, Errol S. Wijelath, Michael Sobel, and Salman Rahman: The "Linker" Region (Amino Acids 38-47) of the Disintegrin Elegantin Is a Novel Inhibitory Domain of Integrin ${alpha}$ ₅ $beta$ ₁-Dependent Cell Adhesion on Fibronectin: EVIDENCE FOR THE NEGATIVE REGULATION OF FIBRONECTIN SYNERGY SITE BIOLOGICAL ACTIVITY
J. Biol. Chem. 2006 281: 37686-37696. First Published on September 18, 2006; doi:10.1074/jbc.M603943200 [Abstract] [Full Text] [PDF]

Samuel W. Straight, Jay N. Pieczynski, Eileen L. Whiteman, Chia-Jen Liu, and Ben Margolis: Mammalian Lin-7 Stabilizes Polarity Protein Complexes
J. Biol. Chem. 2006 281: 37738-37747. First Published on October 1, 2006; doi:10.1074/jbc.M607059200 [Abstract] [Full Text] [PDF]

Jérôme Govin, Cécile Caron, Emmanuelle Escoffier, Myriam Ferro, Lauriane Kuhn, Sophie Rousseaux, Edward M. Eddy, Jérôme Garin, and Saadi Khochbin: Post-meiotic Shifts in HSPA2/HSP70.2 Chaperone Activity during Mouse Spermatogenesis
J. Biol. Chem. 2006 281: 37888-37892. First Published on October 11, 2006; doi:10.1074/jbc.M608147200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Yuichiro Miyaoka, Minoru Tanaka, Takahiro Naiki, and Atsushi Miyajima: Oncostatin M Inhibits Adipogenesis through the RAS/ERK and STAT5 Signaling Pathways
J. Biol. Chem. 2006 281: 37913-37920. First Published on October 6, 2006; doi:10.1074/jbc.M606089200 [Abstract] [Full Text] [PDF]

Luigi Notari, Victoriano Baladron, J. Daniel Aroca-Aguilar, Natalia Balko, Raul Heredia, Christina Meyer, Patricia M. Notario, Senthil Saravanamuthu, Maria-Luisa Nueda, Francisco Sanchez-Sanchez, Julio Escribano, Jorge Laborda, and S. Patricia Becerra: Identification of a Lipase-linked Cell Membrane Receptor for Pigment Epithelium-derived Factor
J. Biol. Chem. 2006 281: 38022-38037. First Published on October 10, 2006; doi:10.1074/jbc.M600353200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Wan Jiao, Jashodeep Datta, Huei-Min Lin, Miroslav Dundr, and Sushil G. Rane: Nucleocytoplasmic Shuttling of the Retinoblastoma Tumor Suppressor Protein via Cdk Phosphorylation-dependent Nuclear Export
J. Biol. Chem. 2006 281: 38098-38108. First Published on October 16, 2006; doi:10.1074/jbc.M605271200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Mechanisms Of Signal Transduction:

Weiqing Zhang, Richard Swanson, Yan Xiong, Benjamin Richard, and Steven T. Olson: Antiangiogenic Antithrombin Blocks the Heparan Sulfate-dependent Binding of Proangiogenic Growth Factors to Their Endothelial Cell Receptors: EVIDENCE FOR DIFFERENTIAL BINDING OF ANTIANGIOGENIC AND ANTICOAGULANT FORMS OF ANTITHROMBIN TO PROANGIOGENIC HEPARAN SULFATE DOMAINS
J. Biol. Chem. 2006 281: 37302-37310. First Published on October 13, 2006; doi:10.1074/jbc.M604905200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Boyi Gan, Youngdong Yoo, and Jun-Lin Guan: Association of Focal Adhesion Kinase with Tuberous Sclerosis Complex 2 in the Regulation of S6 Kinase Activation and Cell Growth
J. Biol. Chem. 2006 281: 37321-37329. First Published on October 16, 2006; doi:10.1074/jbc.M605241200 [Abstract] [Full Text] [PDF]

Indranil Mukhopadhyay, Edward A. Sausville, James H. Doroshow, and Krishnendu K. Roy: Molecular Mechanism of Adaphostin-mediated G₁ Arrest in Prostate Cancer (PC-3) Cells: SIGNALING EVENTS MEDIATED BY HEPATOCYTE GROWTH FACTOR RECEPTOR, c-Met, AND p38 MAPK PATHWAYS
J. Biol. Chem. 2006 281: 37330-37344. First Published on September 6, 2006; doi:10.1074/jbc.M605569200 [Abstract] [Full Text] [PDF]

Ralph J. DeBerardinis, Julian J. Lum, and Craig B. Thompson: Phosphatidylinositol 3-Kinase-dependent Modulation of Carnitine Palmitoyltransferase 1A Expression Regulates Lipid Metabolism during Hematopoietic Cell Growth
J. Biol. Chem. 2006 281: 37372-37380. First Published on October 9, 2006; doi:10.1074/jbc.M608372200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Sic. L. Chan, Dong Liu, George A. Kyriazis, Pamela Bagsiyao, Xin Ouyang, and Mark P. Mattson: Mitochondrial Uncoupling Protein-4 Regulates Calcium Homeostasis and Sensitivity to Store Depletion-induced Apoptosis in Neural Cells
J. Biol. Chem. 2006 281: 37391-37403. First Published on October 11, 2006; doi:10.1074/jbc.M605552200 [Abstract] [Full Text] [PDF]

Juan Du, David H. Daniels, Carla Asbury, Sujatha Venkataraman, Jingru Liu, Douglas R. Spitz, Larry W. Oberley, and Joseph J. Cullen: Mitochondrial Production of Reactive Oxygen Species Mediate Dicumarol-induced Cytotoxicity in Cancer Cells
J. Biol. Chem. 2006 281: 37416-37426. First Published on October 13, 2006; doi:10.1074/jbc.M605063200 [Abstract] [Full Text] [PDF]

Jianyong Wang, Yu Shao, Teri A. Bennett, Raji A. Shankar, Paul D. Wightman, and Laxma G. Reddy: The Functional Effects of Physical Interactions among Toll-like Receptors 7, 8, and 9
J. Biol. Chem. 2006 281: 37427-37434. First Published on October 13, 2006; doi:10.1074/jbc.M605311200 [Abstract] [Full Text] [PDF]

Andreas Breit, Katharina Wolff, Hermann Kalwa, Hubertus Jarry, Thomas Büch, and Thomas Gudermann: The Natural Inverse Agonist Agouti-related Protein Induces Arrestin-mediated Endocytosis of Melanocortin-3 and -4 Receptors
J. Biol. Chem. 2006 281: 37447-37456. First Published on October 14, 2006; doi:10.1074/jbc.M605982200 [Abstract] [Full Text] [PDF]

Katarzyna Modzelewska, Laura P. Newman, Radhika Desai, and Patricia J. Keely: Ack1 Mediates Cdc42-dependent Cell Migration and Signaling to p130^Cas
J. Biol. Chem. 2006 281: 37527-37535. First Published on October 12, 2006; doi:10.1074/jbc.M604342200 [Abstract] [Full Text] [PDF]

Richard G. Anthony, Safina Khan, Joana Costa, Maria S. Pais, and László Bögre: The Arabidopsis Protein Kinase PTI1-2 Is Activated by Convergent Phosphatidic Acid and Oxidative Stress Signaling Pathways Downstream of PDK1 and OXI1
J. Biol. Chem. 2006 281: 37536-37546. First Published on October 13, 2006; doi:10.1074/jbc.M607341200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Runsheng Li, Cherry Luo, Marjelo Mines, Jingwu Zhang, and Guo-Huang Fan: Chemokine CXCL12 Induces Binding of Ferritin Heavy Chain to the Chemokine Receptor CXCR4, Alters CXCR4 Signaling, and Induces Phosphorylation and Nuclear Translocation of Ferritin Heavy Chain
J. Biol. Chem. 2006 281: 37616-37627. First Published on October 19, 2006; doi:10.1074/jbc.M607266200 [Abstract] [Full Text] [PDF]

Manu Agarwal, Yujin Hao, Avnish Kapoor, Chun-Hai Dong, Hiroaki Fujii, Xianwu Zheng, and Jian-Kang Zhu: A R2R3 Type MYB Transcription Factor Is Involved in the Cold Regulation of CBF Genes and in Acquired Freezing Tolerance
J. Biol. Chem. 2006 281: 37636-37645. First Published on October 2, 2006; doi:10.1074/jbc.M605895200 [Abstract] [Full Text] [PDF]

Cezar Stoica, Jon B. Carmichael, Henry Parker, Justin Pare, and Tom C. Hobman: Interactions between the RNA Interference Effector Protein Ago1 and 14-3-3 Proteins: CONSEQUENCES FOR CELL CYCLE PROGRESSION
J. Biol. Chem. 2006 281: 37646-37651. First Published on October 16, 2006; doi:10.1074/jbc.M604476200 [Abstract] [Full Text] [PDF]

K. Martin Hoffmann, Jose A. Tapia, Marc J. Berna, Michelle Thill, Till Braunschweig, Samuel A. Mantey, Terry W. Moody, and Robert T. Jensen: Gastrointestinal Hormones Cause Rapid c-Met Receptor Down-regulation by a Novel Mechanism Involving Clathrin-mediated Endocytosis and a Lysosome-dependent Mechanism
J. Biol. Chem. 2006 281: 37705-37719. First Published on October 10, 2006; doi:10.1074/jbc.M602583200 [Abstract] [Full Text] [PDF]

Nicole E. Willmarth and Stephen P. Ethier: Autocrine and Juxtacrine Effects of Amphiregulin on the Proliferative, Invasive, and Migratory Properties of Normal and Neoplastic Human Mammary Epithelial Cells
J. Biol. Chem. 2006 281: 37728-37737. First Published on October 10, 2006; doi:10.1074/jbc.M606532200 [Abstract] [Full Text] [PDF]

Jiao-Hui Wu, Robi Goswami, Xinjiang Cai, Sabrina T. Exum, Xuewei Huang, Lisheng Zhang, Leigh Brian, Richard T. Premont, Karsten Peppel, and Neil J. Freedman: Regulation of the Platelet-derived Growth Factor Receptor- $beta$ by G Protein-coupled Receptor Kinase-5 in Vascular Smooth Muscle Cells Involves the Phosphatase Shp2
J. Biol. Chem. 2006 281: 37758-37772. First Published on October 3, 2006; doi:10.1074/jbc.M605756200 [Abstract] [Full Text] [PDF]

Lincoln D. Nadauld, Reid Phelps, Brent C. Moore, Annie Eisinger, Imelda T. Sandoval, Stephanie Chidester, Peter W. Peterson, Elizabeth J. Manos, Bradford Sklow, Randall W. Burt, and David A. Jones: Adenomatous Polyposis Coli Control of C-terminal Binding Protein-1 Stability Regulates Expression of Intestinal Retinol Dehydrogenases
J. Biol. Chem. 2006 281: 37828-37835. First Published on October 6, 2006; doi:10.1074/jbc.M602119200 [Abstract] [Full Text] [PDF]

Thomas P. Conrads, Gillian M. Tocci, Brian L. Hood, Chen-Ou Zhang, Li Guo, Kristopher R. Koch, Christopher J. Michejda, Timothy D. Veenstra, and Susan K. Keay: CKAP4/p63 Is a Receptor for the Frizzled-8 Protein-related Antiproliferative Factor from Interstitial Cystitis Patients
J. Biol. Chem. 2006 281: 37836-37843. First Published on October 8, 2006; doi:10.1074/jbc.M604581200 [Abstract] [Full Text] [PDF]

Shin-ichi Maeda, Chieko Sugita, Mamoru Sugita, and Tatsuo Omata: A New Class of Signal Transducer in His-Asp Phosphorelay Systems
J. Biol. Chem. 2006 281: 37868-37876. First Published on October 12, 2006; doi:10.1074/jbc.M608680200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Wei Yang, Christopher V. Carman, Minsoo Kim, Azucena Salas, Motomu Shimaoka, and Timothy A. Springer: A Small Molecule Agonist of an Integrin, ${alpha}$ _L $beta$ ₂
J. Biol. Chem. 2006 281: 37904-37912. First Published on October 5, 2006; doi:10.1074/jbc.M606888200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Jennifer J. Tate, André Feller, Evelyne Dubois, and Terrance G. Cooper: Saccharomyces cerevisiae Sit4 Phosphatase Is Active Irrespective of the Nitrogen Source Provided, and Gln3 Phosphorylation Levels Become Nitrogen Source-responsive in a sit4-deleted Strain
J. Biol. Chem. 2006 281: 37980-37992. First Published on October 2, 2006; doi:10.1074/jbc.M606973200 [Abstract] [Full Text] [PDF] [Supplemental Data]