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On The Cover: The cover illustrates a segment of the cell cycle at which a cell proceeds from interphase into mitosis (α-tubulin, red; DNA, blue). The SCF ubiquitin ligase defined by the F-box-containing protein NIPA (green) becomes part of a regulatory feedback loop with its target cyclin B1 to maintain the fidelity of this process. For details see the article by Bassermann, pages 15965–15972.

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