JBC -- Table of Contents (Jan 26 2007, 282, (4))

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Classics:

Nicole Kresge, Robert D. Simoni, and Robert L. Hill: DNA Polymerase and Leading and Lagging Strand Synthesis: the Work of Bruce Alberts
The slow dissociation of the T4 DNA polymerase holoenzyme when stalled by nucleotide omission. An indication of a highly processive enzyme (KJ Hacker and BM Alberts J. Biol. Chem. 269, 24209-24220)
The rapid dissociation of the T4 DNA polymerase holoenzyme when stopped by a DNA hairpin helix. A model for polymerase release following the termination of each Okazaki fragment (KJ Hacker and BM Alberts J. Biol. Chem. 269, 24221-24228)
J. Biol. Chem. 2007 282: e3. [Full Text]

Minireviews:

Sarah Spiegel and Sheldon Milstien: Functions of the Multifaceted Family of Sphingosine Kinases and Some Close Relatives
J. Biol. Chem. 2007 282: 2125-2129. First Published on November 29, 2006; doi:10.1074/jbc.R600028200 [Full Text] [PDF]

Accelerated Publications:

Keith Woods, J. Michael Thomson, and Scott M. Hammond: Direct Regulation of an Oncogenic Micro-RNA Cluster by E2F Transcription Factors
J. Biol. Chem. 2007 282: 2130-2134. First Published on November 29, 2006; doi:10.1074/jbc.C600252200 [Abstract] [Full Text] [PDF]

DNA: Replication, Repair, and Recombination:

Stephanie A. Nick McElhinny, Carrie M. Stith, Peter M. J. Burgers, and Thomas A. Kunkel: Inefficient Proofreading and Biased Error Rates during Inaccurate DNA Synthesis by a Mutant Derivative of Saccharomyces cerevisiae DNA Polymerase ${delta}$
J. Biol. Chem. 2007 282: 2324-2332. First Published on November 22, 2006; doi:10.1074/jbc.M609591200 [Abstract] [Full Text] [PDF]

Naoko Yoshizawa-Sugata and Hisao Masai: Human Tim/Timeless-interacting Protein, Tipin, Is Required for Efficient Progression of S Phase and DNA Replication Checkpoint
J. Biol. Chem. 2007 282: 2729-2740. First Published on November 13, 2006; doi:10.1074/jbc.M605596200 [Abstract] [Full Text] [PDF]

Genes: Structure and Regulation:

Yannick Sylvestre, Vincent De Guire, Emmanuelle Querido, Utpal K. Mukhopadhyay, Véronique Bourdeau, François Major, Gerardo Ferbeyre, and Pascal Chartrand: An E2F/miR-20a Autoregulatory Feedback Loop
J. Biol. Chem. 2007 282: 2135-2143. First Published on November 29, 2006; doi:10.1074/jbc.M608939200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Thomas Uhlmann, Stefan Boeing, Michael Lehmbacher, and Michael Meisterernst: The VP16 Activation Domain Establishes an Active Mediator Lacking CDK8 in Vivo
J. Biol. Chem. 2007 282: 2163-2173. First Published on November 29, 2006; doi:10.1074/jbc.M608451200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Noriko Haraguchi, Tomoko Andoh, David Frendewey, and Tokio Tani: Mutations in the SF1-U2AF⁵⁹-U2AF²³ Complex Cause Exon Skipping in Schizosaccharomyces pombe
J. Biol. Chem. 2007 282: 2221-2228. First Published on November 27, 2006; doi:10.1074/jbc.M609430200 [Abstract] [Full Text] [PDF]

Stephan Lindsey, Weiqi Huang, Hao Wang, Elizabeth Horvath, Chunliu Zhu, and Elizabeth A. Eklund: Activation of SHP2 Protein-tyrosine Phosphatase Increases HoxA10-induced Repression of the Genes Encoding gp91^PHOX and p67^PHOX
J. Biol. Chem. 2007 282: 2237-2249. First Published on November 30, 2006; doi:10.1074/jbc.M608642200 [Abstract] [Full Text] [PDF]

Dawn R. Cochrane, Zhou Wang, Motosugu Muramaki, Martin E. Gleave, and Colleen C. Nelson: Differential Regulation of Clusterin and Its Isoforms by Androgens in Prostate Cells
J. Biol. Chem. 2007 282: 2278-2287. First Published on December 4, 2006; doi:10.1074/jbc.M608162200 [Abstract] [Full Text] [PDF]

Amar Bir Singh Sidhu, Qingan Sun, Louis J. Nkrumah, Michael W. Dunne, James C. Sacchettini, and David A. Fidock: In Vitro Efficacy, Resistance Selection, and Structural Modeling Studies Implicate the Malarial Parasite Apicoplast as the Target of Azithromycin
J. Biol. Chem. 2007 282: 2494-2504. First Published on November 15, 2006; doi:10.1074/jbc.M608615200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Tapani Ronni, Kimberly J. Payne, Sam Ho, Michelle N. Bradley, Glenn Dorsam, and Sinisa Dovat: Human Ikaros Function in Activated T Cells Is Regulated by Coordinated Expression of Its Largest Isoforms
J. Biol. Chem. 2007 282: 2538-2547. First Published on November 29, 2006; doi:10.1074/jbc.M605627200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Pierre-Olivier Estève, Hang Gyeong Chin, and Sriharsa Pradhan: Molecular Mechanisms of Transactivation and Doxorubicin-mediated Repression of survivin Gene in Cancer Cells
J. Biol. Chem. 2007 282: 2615-2625. First Published on November 22, 2006; doi:10.1074/jbc.M606203200 [Abstract] [Full Text] [PDF] [Supplemental Data]

RNA: Structure, Metabolism, and Catalysis:

Hui Zhu, Hua-Lin Zhou, Robert A. Hasman, and Hua Lou: Hu Proteins Regulate Polyadenylation by Blocking Sites Containing U-rich Sequences
J. Biol. Chem. 2007 282: 2203-2210. First Published on November 26, 2006; doi:10.1074/jbc.M609349200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Protein Synthesis, Post-Translation Modification, and Degradation:

Toshihiro Okada, Hideyuki Suzuki, Kei Wada, Hidehiko Kumagai, and Keiichi Fukuyama: Crystal Structure of the ${gamma}$ -Glutamyltranspeptidase Precursor Protein from Escherichia coli: STRUCTURAL CHANGES UPON AUTOCATALYTIC PROCESSING AND IMPLICATIONS FOR THE MATURATION MECHANISM
J. Biol. Chem. 2007 282: 2433-2439. First Published on November 29, 2006; doi:10.1074/jbc.M607490200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Xiaobing Shi, Ioulia Kachirskaia, Kay L. Walter, Jen-Hao A. Kuo, Aimee Lake, Foteini Davrazou, Steve M. Chan, David G. E. Martin, Ian M. Fingerman, Scott D. Briggs, LeAnn Howe, Paul J. Utz, Tatiana G. Kutateladze, Alexey A. Lugovskoy, Mark T. Bedford, and Or Gozani: Proteome-wide Analysis in Saccharomyces cerevisiae Identifies Several PHD Fingers as Novel Direct and Selective Binding Modules of Histone H3 Methylated at Either Lysine 4 or Lysine 36
J. Biol. Chem. 2007 282: 2450-2455. First Published on December 1, 2006; doi:10.1074/jbc.C600286200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Shinobu Chiba, Kristina Coleman, and Kit Pogliano: Impact of Membrane Fusion and Proteolysis on SpoIIQ Dynamics and Interaction with SpoIIIAH
J. Biol. Chem. 2007 282: 2576-2586. First Published on November 22, 2006; doi:10.1074/jbc.M606056200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Nadeem Wajih, Susan M Hutson, and Reidar Wallin: Disulfide-dependent Protein Folding Is Linked to Operation of the Vitamin K Cycle in the Endoplasmic Reticulum: A PROTEIN DISULFIDE ISOMERASE-VKORC1 REDOX ENZYME COMPLEX APPEARS TO BE RESPONSIBLE FOR VITAMIN K₁ 2,3-EPOXIDE REDUCTION
J. Biol. Chem. 2007 282: 2626-2635. First Published on November 23, 2006; doi:10.1074/jbc.M608954200 [Abstract] [Full Text] [PDF]

Monica Averna, Roberto Stifanese, Roberta De Tullio, Mario Passalacqua, Enrico Defranchi, Franca Salamino, Edon Melloni, and Sandro Pontremoli: Regulation of Calpain Activity in Rat Brain with Altered Ca²⁺ Homeostasis
J. Biol. Chem. 2007 282: 2656-2665. First Published on November 29, 2006; doi:10.1074/jbc.M606919200 [Abstract] [Full Text] [PDF]

Protein Structure and Folding:

Coen Maas, Suzanne Hermeling, Barend Bouma, Wim Jiskoot, and Martijn F. B. G. Gebbink: A Role for Protein Misfolding in Immunogenicity of Biopharmaceuticals
J. Biol. Chem. 2007 282: 2229-2236. First Published on November 29, 2006; doi:10.1074/jbc.M605984200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Yuko Fujiwara, Daniel A. Osborne, Michelle D. Walker, De-an Wang, Debra A. Bautista, Karoly Liliom, James R. Van Brocklyn, Abby L. Parrill, and Gabor Tigyi: Identification of the Hydrophobic Ligand Binding Pocket of the S1P₁ Receptor
J. Biol. Chem. 2007 282: 2374-2385. First Published on November 18, 2006; doi:10.1074/jbc.M609648200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Nicole M. Koropatkin, David W. Koppenaal, Himadri B. Pakrasi, and Thomas J. Smith: The Structure of a Cyanobacterial Bicarbonate Transport Protein, CmpA
J. Biol. Chem. 2007 282: 2606-2614. First Published on November 22, 2006; doi:10.1074/jbc.M610222200 [Abstract] [Full Text] [PDF]

Song Xiang, Gerlinde Usunow, Gudrun Lange, Marco Busch, and Liang Tong: Crystal Structure of 1-Deoxy-D-xylulose 5-Phosphate Synthase, a Crucial Enzyme for Isoprenoids Biosynthesis
J. Biol. Chem. 2007 282: 2676-2682. First Published on November 29, 2006; doi:10.1074/jbc.M610235200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Ken Kitano, Nozomi Yoshihara, and Toshio Hakoshima: Crystal Structure of the HRDC Domain of Human Werner Syndrome Protein, WRN
J. Biol. Chem. 2007 282: 2717-2728. First Published on December 4, 2006; doi:10.1074/jbc.M610142200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Enzyme Catalysis and Regulation:

Zhi-Qiang Wang, Rachel J. Lawson, Madhavan R. Buddha, Chin-Chuan Wei, Brian R. Crane, Andrew W. Munro, and Dennis J. Stuehr: Bacterial Flavodoxins Support Nitric Oxide Production by Bacillus subtilis Nitric-oxide Synthase
J. Biol. Chem. 2007 282: 2196-2202. First Published on November 24, 2006; doi:10.1074/jbc.M608206200 [Abstract] [Full Text] [PDF] [Supplemental Data] [Summary]

Richard Swanson, Manikanahally P. Raghavendra, Weiqing Zhang, Christopher Froelich, Peter G. W. Gettins, and Steven T. Olson: Serine and Cysteine Proteases Are Translocated to Similar Extents upon Formation of Covalent Complexes with Serpins: FLUORESCENCE PERTURBATION AND FLUORESCENCE RESONANCE ENERGY TRANSFER MAPPING OF THE PROTEASE BINDING SITE IN CrmA COMPLEXES WITH GRANZYME B AND CASPASE-1
J. Biol. Chem. 2007 282: 2305-2313. First Published on December 1, 2006; doi:10.1074/jbc.M609546200 [Abstract] [Full Text] [PDF]

Carla A. Borgoño, Iacovos P. Michael, Julie L. V. Shaw, Liu-Ying Luo, Manik C. Ghosh, Antoninus Soosaipillai, Linda Grass, Dionyssios Katsaros, and Eleftherios P. Diamandis: Expression and Functional Characterization of the Cancer-related Serine Protease, Human Tissue Kallikrein 14
J. Biol. Chem. 2007 282: 2405-2422. First Published on November 16, 2006; doi:10.1074/jbc.M608348200 [Abstract] [Full Text] [PDF]

René M. de Jong, Paola Bazzacco, Gerrit J. Poelarends, William H. Johnson, Jr., Yoon Jae Kim, Elizabeth A. Burks, Hector Serrano, Andy-Mark W. H. Thunnissen, Christian P. Whitman, and Bauke W. Dijkstra: Crystal Structures of Native and Inactivated cis-3-Chloroacrylic Acid Dehalogenase: STRUCTURAL BASIS FOR SUBSTRATE SPECIFICITY AND INACTIVATION BY (R)-OXIRANE-2-CARBOXYLATE
J. Biol. Chem. 2007 282: 2440-2449. First Published on November 22, 2006; doi:10.1074/jbc.M608134200 [Abstract] [Full Text] [PDF]

Tiina Holster, Outi Pakkanen, Raija Soininen, Raija Sormunen, Minna Nokelainen, Kari I. Kivirikko, and Johanna Myllyharju: Loss of Assembly of the Main Basement Membrane Collagen, Type IV, but Not Fibril-forming Collagens and Embryonic Death in Collagen Prolyl 4-Hydroxylase I Null Mice
J. Biol. Chem. 2007 282: 2512-2519. First Published on November 29, 2006; doi:10.1074/jbc.M606608200 [Abstract] [Full Text] [PDF]

Rebecca K. Holmes, Fransje A. Koning, Kate N. Bishop, and Michael H. Malim: APOBEC3F Can Inhibit the Accumulation of HIV-1 Reverse Transcription Products in the Absence of Hypermutation: COMPARISONS WITH APOBEC3G
J. Biol. Chem. 2007 282: 2587-2595. First Published on November 22, 2006; doi:10.1074/jbc.M607298200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Martin St. Maurice, Paola E. Mera, María P. Taranto, Fernando Sesma, Jorge C. Escalante-Semerena, and Ivan Rayment: Structural Characterization of the Active Site of the PduO-Type ATP:Co(I)rrinoid Adenosyltransferase from Lactobacillus reuteri
J. Biol. Chem. 2007 282: 2596-2605. First Published on November 22, 2006; doi:10.1074/jbc.M609557200 [Abstract] [Full Text] [PDF]

Metabolism and Bioenergetics:

Nicholas M. Brown, Sean M. Martin, Nick Maurice, Tomomi Kuwana, and C. Michael Knudson: Caspase Inhibition Blocks Cell Death and Results in Cell Cycle Arrest in Cytokine-deprived Hematopoietic Cells
J. Biol. Chem. 2007 282: 2144-2155. First Published on November 13, 2006; doi:10.1074/jbc.M607961200 [Abstract] [Full Text] [PDF]

Chang-Yi Wu, Amanda J. Bird, Dennis R. Winge, and David J. Eide: Regulation of the Yeast TSA1 Peroxiredoxin by ZAP1 Is an Adaptive Response to the Oxidative Stress of Zinc Deficiency
J. Biol. Chem. 2007 282: 2184-2195. First Published on November 22, 2006; doi:10.1074/jbc.M606639200 [Abstract] [Full Text] [PDF]

Kyle A. Rasbach and Rick G. Schnellmann: Signaling of Mitochondrial Biogenesis following Oxidant Injury
J. Biol. Chem. 2007 282: 2355-2362. First Published on November 20, 2006; doi:10.1074/jbc.M608009200 [Abstract] [Full Text] [PDF]

Toyoyoshi Uchida, Noseki Iwashita, Mica Ohara-Imaizumi, Takeshi Ogihara, Shintaro Nagai, Jong Bock Choi, Yoshifumi Tamura, Norihiro Tada, Ryuzo Kawamori, Keiichi I. Nakayama, Shinya Nagamatsu, and Hirotaka Watada: Protein Kinase C ${delta}$ Plays a Non-redundant Role in Insulin Secretion in Pancreatic $beta$ Cells
J. Biol. Chem. 2007 282: 2707-2716. First Published on November 29, 2006; doi:10.1074/jbc.M610482200 [Abstract] [Full Text] [PDF]

Glycobiology and Extracellular Matrices:

Karl M. Stuhlmeier: The Anti-rheumatic Gold Salt Aurothiomalate Suppresses Interleukin-1 $beta$ -induced Hyaluronan Accumulation by Blocking HAS1 Transcription and by Acting as a COX-2 Transcriptional Repressor
J. Biol. Chem. 2007 282: 2250-2258. First Published on November 3, 2006; doi:10.1074/jbc.M605011200 [Abstract] [Full Text] [PDF]

Xiulong Xu, Geetha Rao, Roderick M. Quiros, Anthony W. Kim, Hua-Quan Miao, Gregory J. Brunn, Jeffrey L. Platt, Paolo Gattuso, and Richard A. Prinz: In Vivo and in Vitro Degradation of Heparan Sulfate (HS) Proteoglycans by HPR1 in Pancreatic Adenocarcinomas: LOSS OF CELL SURFACE HS SUPPRESSES FIBROBLAST GROWTH FACTOR 2-MEDIATED CELL SIGNALING AND PROLIFERATION
J. Biol. Chem. 2007 282: 2363-2373. First Published on November 22, 2006; doi:10.1074/jbc.M604218200 [Abstract] [Full Text] [PDF]

Linda O. Tremblay, Erzsebet Nagy Kovács, Eugene Daniels, Nyet Kui Wong, Mark Sutton-Smith, Howard R. Morris, Anne Dell, Edwige Marcinkiewicz, Nabil G. Seidah, Colin McKerlie, and Annette Herscovics: Respiratory Distress and Neonatal Lethality in Mice Lacking Golgi ${alpha}$ 1,2-Mannosidase IB Involved in N-Glycan Maturation
J. Biol. Chem. 2007 282: 2558-2566. First Published on November 22, 2006; doi:10.1074/jbc.M608661200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Naoki Yamamoto, Etsuro Matsubara, Sumihiro Maeda, Hirohisa Minagawa, Akihiko Takashima, Wakako Maruyama, Makoto Michikawa, and Katsuhiko Yanagisawa: A Ganglioside-induced Toxic Soluble A $beta$ Assembly: ITS ENHANCED FORMATION FROM A $beta$ BEARING THE ARCTIC MUTATION
J. Biol. Chem. 2007 282: 2646-2655. First Published on November 29, 2006; doi:10.1074/jbc.M606202200 [Abstract] [Full Text] [PDF]

Lipids and Lipoproteins:

Harini Sampath, Makoto Miyazaki, Agnieszka Dobrzyn, and James M. Ntambi: Stearoyl-CoA Desaturase-1 Mediates the Pro-lipogenic Effects of Dietary Saturated Fat
J. Biol. Chem. 2007 282: 2483-2493. First Published on November 23, 2006; doi:10.1074/jbc.M610158200 [Abstract] [Full Text] [PDF]

Ling Gao, Jiakun Wang, Konjeti R. Sekhar, Huiyong Yin, Nicholas F. Yared, Scott N. Schneider, Soumya Sasi, Timothy P. Dalton, Mark E. Anderson, Jefferson Y. Chan, Jason D. Morrow, and Michael L. Freeman: Novel n-3 Fatty Acid Oxidation Products Activate Nrf2 by Destabilizing the Association between Keap1 and Cullin3
J. Biol. Chem. 2007 282: 2529-2537. First Published on November 25, 2006; doi:10.1074/jbc.M607622200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Membrane Transport, Structure, Function, and Biogenesis:

Giovanni Gonzalez-Gutierrez, Erick Miranda-Laferte, Alan Neely, and Patricia Hidalgo: The Src Homology 3 Domain of the $beta$ -Subunit of Voltage-gated Calcium Channels Promotes Endocytosis via Dynamin Interaction
J. Biol. Chem. 2007 282: 2156-2162. First Published on November 16, 2006; doi:10.1074/jbc.M609071200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Adrien Renaudo, Sébastien L'Hoste, Hélène Guizouarn, Franck Borgèse, and Olivier Soriani: Cancer Cell Cycle Modulated by a Functional Coupling between Sigma-1 Receptors and Cl^– Channels
J. Biol. Chem. 2007 282: 2259-2267. First Published on November 22, 2006; doi:10.1074/jbc.M607915200 [Abstract] [Full Text] [PDF]

Dominique Pontier, Catherine Albrieux, Jacques Joyard, Thierry Lagrange, and Maryse A. Block: Knock-out of the Magnesium Protoporphyrin IX Methyltransferase Gene in Arabidopsis: EFFECTS ON CHLOROPLAST DEVELOPMENT AND ON CHLOROPLAST-TO-NUCLEUS SIGNALING
J. Biol. Chem. 2007 282: 2297-2304. First Published on November 29, 2006; doi:10.1074/jbc.M610286200 [Abstract] [Full Text] [PDF]

Alexandre Hinzpeter, Janine Fritsch, Florence Borot, Stéphanie Trudel, Diane-Lore Vieu, Franck Brouillard, Maryvonne Baudouin-Legros, Jérôme Clain, Aleksander Edelman, and Mario Ollero: Membrane Cholesterol Content Modulates ClC-2 Gating and Sensitivity to Oxidative Stress
J. Biol. Chem. 2007 282: 2423-2432. First Published on November 15, 2006; doi:10.1074/jbc.M608251200 [Abstract] [Full Text] [PDF]

Annabelle Schnaith, Hamid Kashkar, Sonja A. Leggio, Klaus Addicks, Martin Krönke, and Oleg Krut: Staphylococcus aureus Subvert Autophagy for Induction of Caspase-independent Host Cell Death
J. Biol. Chem. 2007 282: 2695-2706. First Published on November 29, 2006; doi:10.1074/jbc.M609784200 [Abstract] [Full Text] [PDF]

Masaki Mishima, Shigeo Wakabayashi, and Chojiro Kojima: Solution Structure of the Cytoplasmic Region of Na⁺/H⁺ Exchanger 1 Complexed with Essential Cofactor Calcineurin B Homologous Protein 1
J. Biol. Chem. 2007 282: 2741-2751. First Published on October 18, 2006; doi:10.1074/jbc.M604092200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Molecular Basis Of Cell and Developmental Biology:

Karina Kulangara, Michel Kropf, Liliane Glauser, Sarah Magnin, Stefano Alberi, Alexandre Yersin, and Harald Hirling: Phosphorylation of Glutamate Receptor Interacting Protein 1 Regulates Surface Expression of Glutamate Receptors
J. Biol. Chem. 2007 282: 2395-2404. First Published on November 22, 2006; doi:10.1074/jbc.M606471200 [Abstract] [Full Text] [PDF]

Si Young Cho, Eui Seok Shin, Pil Joon Park, Dong Wook Shin, Hui Kyoung Chang, Daegun Kim, Hyoung Ho Lee, Jeong Ho Lee, Shin Hyoung Kim, Min Jung Song, Ih-Seop Chang, Ok Sub Lee, and Tae Ryong Lee: Identification of Mouse Prp19p as a Lipid Droplet-associated Protein and Its Possible Involvement in the Biogenesis of Lipid Droplets
J. Biol. Chem. 2007 282: 2456-2465. First Published on November 20, 2006; doi:10.1074/jbc.M608042200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Joanna Zawacka-Pankau, Natalia Issaeva, Shakil Hossain, Aladdin Pramanik, Galina Selivanova, and Anna J. Podhajska: Protoporphyrin IX Interacts with Wild-type p53 Protein in Vitro and Induces Cell Death of Human Colon Cancer Cells in a p53-dependent and -independent Manner
J. Biol. Chem. 2007 282: 2466-2472. First Published on November 29, 2006; doi:10.1074/jbc.M608906200 [Abstract] [Full Text] [PDF]

Young-Joo Jang, Jae-Hoon Ji, Young-Chul Choi, Chun Jeih Ryu, and Seon-Yle Ko: Regulation of Polo-like Kinase 1 by DNA Damage in Mitosis: INHIBITION OF MITOTIC PLK-1 BY PROTEIN PHOSPHATASE 2A
J. Biol. Chem. 2007 282: 2473-2482. First Published on November 22, 2006; doi:10.1074/jbc.M605480200 [Abstract] [Full Text] [PDF]

Mukesh Pasupuleti, Björn Walse, Emma Andersson Nordahl, Matthias Mörgelin, Martin Malmsten, and Artur Schmidtchen: Preservation of Antimicrobial Properties of Complement Peptide C3a, from Invertebrates to Humans
J. Biol. Chem. 2007 282: 2520-2528. First Published on November 27, 2006; doi:10.1074/jbc.M607848200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Sergey Yaklichkin, Aaron B. Steiner, Qun Lu, and Daniel S. Kessler: FoxD3 and Grg4 Physically Interact to Repress Transcription and Induce Mesoderm in Xenopus
J. Biol. Chem. 2007 282: 2548-2557. First Published on November 30, 2006; doi:10.1074/jbc.M607412200 [Abstract] [Full Text] [PDF]

Ronald L. Mellgren, Wenli Zhang, Katsuya Miyake, and Paul L. McNeil: Calpain Is Required for the Rapid, Calcium-dependent Repair of Wounded Plasma Membrane
J. Biol. Chem. 2007 282: 2567-2575. First Published on November 22, 2006; doi:10.1074/jbc.M604560200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Teeru Bihani, Agustin Chicas, Crystal Pui-Kwan Lo, and Athena W. Lin: Dissecting the Senescence-like Program in Tumor Cells Activated by Ras Signaling
J. Biol. Chem. 2007 282: 2666-2675. First Published on November 29, 2006; doi:10.1074/jbc.M608127200 [Abstract] [Full Text] [PDF] [Supplemental data]

Mechanisms Of Signal Transduction:

Andreas Wicovsky, Nicole Müller, Neda Daryab, Ralf Marienfeld, Christian Kneitz, Shyam Kavuri, Martin Leverkus, Bernd Baumann, and Harald Wajant: Sustained JNK Activation in Response to Tumor Necrosis Factor Is Mediated by Caspases in a Cell Type-specific Manner
J. Biol. Chem. 2007 282: 2174-2183. First Published on November 22, 2006; doi:10.1074/jbc.M606167200 [Abstract] [Full Text] [PDF]

Kim U. Birkenkamp, Abdelkader Essafi, Kristan E. van der Vos, Marco da Costa, Rosaline C.-Y. Hui, Frank Holstege, Leo Koenderman, Eric W.-F. Lam, and Paul J. Coffer: FOXO3a Induces Differentiation of Bcr-Abl-transformed Cells through Transcriptional Down-regulation of Id1
J. Biol. Chem. 2007 282: 2211-2220. First Published on November 27, 2006; doi:10.1074/jbc.M606669200 [Abstract] [Full Text] [PDF]

Claudia Trasak, Gerhardt Zenner, Annette Vogel, Gülnihal Yüksekdag, René Rost, Ilka Haase, Markus Fischer, Lars Israel, Axel Imhof, Stefan Linder, Michael Schleicher, and Martin Aepfelbacher: Yersinia Protein Kinase YopO Is Activated by A Novel G-actin Binding Process
J. Biol. Chem. 2007 282: 2268-2277. First Published on November 22, 2006; doi:10.1074/jbc.M610071200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Maria Malmlöf, Emilie Roudier, Johan Högberg, and Ulla Stenius: MEK-ERK-mediated Phosphorylation of Mdm2 at Ser-166 in Hepatocytes: Mdm2 IS ACTIVATED IN RESPONSE TO INHIBITED Akt SIGNALING
J. Biol. Chem. 2007 282: 2288-2296. First Published on November 15, 2006; doi:10.1074/jbc.M604953200 [Abstract] [Full Text] [PDF]

Jean Chemin, Joel Nargeot, and Philippe Lory: Chemical Determinants Involved in Anandamide-induced Inhibition of T-type Calcium Channels
J. Biol. Chem. 2007 282: 2314-2323. First Published on November 22, 2006; doi:10.1074/jbc.M610033200 [Abstract] [Full Text] [PDF]

Simona Baldassa, Nerina Gnesutta, Umberto Fascio, Emmapaola Sturani, and Renata Zippel: SCLIP, a Microtubule-destabilizing Factor, Interacts with RasGRF1 and Inhibits Its Ability to Promote Rac Activation and Neurite Outgrowth
J. Biol. Chem. 2007 282: 2333-2345. First Published on November 29, 2006; doi:10.1074/jbc.M604495200 [Abstract] [Full Text] [PDF]

Chih-Hsin Tang, Tsui-Ling Hsu, Wan-Wan Lin, Ming-Zong Lai, Rong-Sen Yang, Shie-Liang Hsieh, and Wen-Mei Fu: Attenuation of Bone Mass and Increase of Osteoclast Formation in Decoy Receptor 3 Transgenic Mice
J. Biol. Chem. 2007 282: 2346-2354. First Published on November 10, 2006; doi:10.1074/jbc.M603070200 [Abstract] [Full Text] [PDF]

Pablo Pelegrin and Annmarie Surprenant: Pannexin-1 Couples to Maitotoxin- and Nigericin-induced Interleukin-1 $beta$ Release through a Dye Uptake-independent Pathway
J. Biol. Chem. 2007 282: 2386-2394. First Published on November 22, 2006; doi:10.1074/jbc.M610351200 [Abstract] [Full Text] [PDF]

Yongsheng Liu, Ning Jiang, Jiangyue Wu, Wei Dai, and Jonathan S. Rosenblum: Polo-like Kinases Inhibited by Wortmannin: LABELING SITE AND DOWNSTREAM EFFECTS
J. Biol. Chem. 2007 282: 2505-2511. First Published on November 29, 2006; doi:10.1074/jbc.M609603200 [Abstract] [Full Text] [PDF]

Man Jiang, Navjotsin Pabla, Robert F. Murphy, Tianxin Yang, Xiao-Ming Yin, Kurt Degenhardt, Eileen White, and Zheng Dong: Nutlin-3 Protects Kidney Cells during Cisplatin Therapy by Suppressing Bax/Bak Activation
J. Biol. Chem. 2007 282: 2636-2645. First Published on November 27, 2006; doi:10.1074/jbc.M606928200 [Abstract] [Full Text] [PDF]

Guanglei Zhuang, Sonja Hunter, Yoonha Hwang, and Jin Chen: Regulation of EphA2 Receptor Endocytosis by SHIP2 Lipid Phosphatase via Phosphatidylinositol 3-Kinase-dependent Rac1 Activation
J. Biol. Chem. 2007 282: 2683-2694. First Published on November 29, 2006; doi:10.1074/jbc.M608509200 [Abstract] [Full Text] [PDF]

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Padmaja Kunapuli, Chitta S. Kasyapa, Lesleyann Hawthorn, and John K. Cowell: LGI1, a putative tumor metastasis suppressor gene, controls in vitro invasiveness and expression of matrix metalloproteinases in glioma cells through the ERK1/2 pathway. VOLUME 279 (2004) PAGES 23151–23157
J. Biol. Chem. 2007 282: 2752. [Full Text] [PDF]