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On The Cover: "Firecrackers." An original painting inspired by the crystal structure of human annexin V (annexin A5), a calcium-dependent phospholipid-binding protein. The protein is highly α-helical and also binds up to 12 calcium ions when attached to membranes. On pages 6126-6135, Jeppesen et al. study the energetics of annexin-membrane binding. Original oil painting by Katherine Kirkpatrick (2004).

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