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On The Cover: The cover shows a neonatal rat heart myocyte stained for actinin (green) and HDAC4 (red) showing HDAC4 localization at the sarcomeres. S-shaped curves represent increased (leftward shift) calcium sensitivity of myofilaments following HDAC inhibition by trichostatin-A treatment. For details see the article by Gupta et al., pages 10135–10146.

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