JBC -- Table of Contents (May 2 2008, 283, (18))

Invitrogen Ultrasensitive Cytokine Assays

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Classics:

Nicole Kresge, Robert D. Simoni, and Robert L. Hill: The Rational Design of Nucleic Acid Inhibitors to Treat Leukemia: the Work of George H. Hitchings
PURINE METABOLISM OF A DIAMINOPURINE-RESISTANT STRAIN OF LACTOBACILLUS CASEI (Gertrude B. Elion, Henry Vanderwerff, George H. Hitchings, M. Earl Balis, Daniel H. Levin, and George Bosworth Brown J. Biol. Chem. 200, 7-16)
THE PURINE METABOLISM OF A 6-MERCAPTOPURINE-RESISTANT LACTOBACILLUS CASEI (Gertrude B. Elion, Samuel Singer, and George H. Hitchings J. Biol. Chem. 204, 35-41)
J. Biol. Chem. 2008 283: e10. [Full Text]

Accelerated Publications:

Tomas Nyman, Pål Stenmark, Susanne Flodin, Ida Johansson, Martin Hammarström, and Pär Nordlund: The Crystal Structure of the Human Toll-like Receptor 10 Cytoplasmic Domain Reveals a Putative Signaling Dimer
J. Biol. Chem. 2008 283: 11861-11865. First Published on March 10, 2008; doi:10.1074/jbc.C800001200 [Abstract] [Full Text] [PDF]

DNA: Replication, Repair, Recombination, and Chromosome Dynamics:

Kenji Fukui, Masami Nishida, Noriko Nakagawa, Ryoji Masui, and Seiki Kuramitsu: Bound Nucleotide Controls the Endonuclease Activity of Mismatch Repair Enzyme MutL
J. Biol. Chem. 2008 283: 12136-12145. First Published on February 29, 2008; doi:10.1074/jbc.M800110200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Changhyun Seong, Michael G. Sehorn, Iben Plate, Idina Shi, Binwei Song, Peter Chi, Uffe Mortensen, Patrick Sung, and Lumir Krejci: Molecular Anatomy of the Recombination Mediator Function of Saccharomyces cerevisiae Rad52
J. Biol. Chem. 2008 283: 12166-12174. First Published on February 29, 2008; doi:10.1074/jbc.M800763200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Dane Hazelbaker, Marco A. Azaro, and Arthur Landy: A Biotin Interference Assay Highlights Two Different Asymmetric Interaction Profiles for ${lambda}$ Integrase Arm-type Binding Sites in Integrative Versus Excisive Recombination
J. Biol. Chem. 2008 283: 12402-12414. First Published on March 4, 2008; doi:10.1074/jbc.M800544200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Transcription, Chromatin, and Epigenetics:

Bindu Ramachandran, Gengsheng Yu, and Tod Gulick: Nuclear Respiratory Factor 1 Controls Myocyte Enhancer Factor 2A Transcription to Provide a Mechanism for Coordinate Expression of Respiratory Chain Subunits
J. Biol. Chem. 2008 283: 11935-11946. First Published on January 24, 2008; doi:10.1074/jbc.M707389200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Hongbo Yang, James J. Pesavento, Taylor W. Starnes, Diane E. Cryderman, Lori L. Wallrath, Neil L. Kelleher, and Craig A. Mizzen: Preferential Dimethylation of Histone H4 Lysine 20 by Suv4-20
J. Biol. Chem. 2008 283: 12085-12092. First Published on February 21, 2008; doi:10.1074/jbc.M707974200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Kristel Vercauteren, Natalie Gleyzer, and Richard C. Scarpulla: PGC-1-related Coactivator Complexes with HCF-1 and NRF-2β in Mediating NRF-2(GABP)-dependent Respiratory Gene Expression
J. Biol. Chem. 2008 283: 12102-12111. First Published on March 14, 2008; doi:10.1074/jbc.M710150200 [Abstract] [Full Text] [PDF]

Rafal Bartoszewski, András Rab, George Twitty, Lauren Stevenson, James Fortenberry, Arkadiusz Piotrowski, Jan P. Dumanski, and Zsuzsa Bebök: The Mechanism of Cystic Fibrosis Transmembrane Conductance Regulator Transcriptional Repression during the Unfolded Protein Response
J. Biol. Chem. 2008 283: 12154-12165. First Published on March 4, 2008; doi:10.1074/jbc.M707610200 [Abstract] [Full Text] [PDF]

Cristina Adán, Yuichi Matsushima, Rosana Hernández-Sierra, Raquel Marco-Ferreres, Miguel Ángel Fernández-Moreno, Emiliano González-Vioque, Manuel Calleja, Juan J. Aragón, Laurie S. Kaguni, and Rafael Garesse: Mitochondrial Transcription Factor B2 Is Essential for Metabolic Function in Drosophila melanogaster Development
J. Biol. Chem. 2008 283: 12333-12342. First Published on February 28, 2008; doi:10.1074/jbc.M801342200 [Abstract] [Full Text] [PDF]

Thomas Eichberger, Alexandra Kaser, Claudia Pixner, Carmen Schmid, Stefan Klingler, Martina Winklmayr, Cornelia Hauser-Kronberger, Fritz Aberger, and Anna-Maria Frischauf: GLI2-specific Transcriptional Activation of the Bone Morphogenetic Protein/Activin Antagonist Follistatin in Human Epidermal Cells
J. Biol. Chem. 2008 283: 12426-12437. First Published on March 3, 2008; doi:10.1074/jbc.M707117200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Hisako Kayama, Vladimir R. Ramirez-Carrozzi, Masahiro Yamamoto, Taketoshi Mizutani, Hirotaka Kuwata, Hideo Iba, Makoto Matsumoto, Kenya Honda, Stephen T. Smale, and Kiyoshi Takeda: Class-specific Regulation of Pro-inflammatory Genes by MyD88 Pathways and I ${kappa}$ B ${zeta}$
J. Biol. Chem. 2008 283: 12468-12477. First Published on March 3, 2008; doi:10.1074/jbc.M709965200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Aaron G. Smith, Nicole Luk, Richard A. Newton, Donald W. Roberts, Richard A. Sturm, and George E. O. Muscat: Melanocortin-1 Receptor Signaling Markedly Induces the Expression of the NR4A Nuclear Receptor Subgroup in Melanocytic Cells
J. Biol. Chem. 2008 283: 12564-12570. First Published on February 21, 2008; doi:10.1074/jbc.M800480200 [Abstract] [Full Text] [PDF]

Chase T. Archer, Agnes Delahodde, Fernando Gonzalez, Stephen Albert Johnston, and Thomas Kodadek: Activation Domain-dependent Monoubiquitylation of Gal4 Protein Is Essential for Promoter Binding in Vivo
J. Biol. Chem. 2008 283: 12614-12623. First Published on March 6, 2008; doi:10.1074/jbc.M801050200 [Abstract] [Full Text] [PDF] [Supplemental Data]

RNA: Processing and Catalysis:

Michael L. Gonzales, David L. Mellman, and Richard A. Anderson: CKI ${alpha}$ Is Associated with and Phosphorylates Star-PAP and Is Also Required for Expression of Select Star-PAP Target Messenger RNAs
J. Biol. Chem. 2008 283: 12665-12673. First Published on February 27, 2008; doi:10.1074/jbc.M800656200 [Abstract] [Full Text] [PDF]

Protein Synthesis, Post-Translational Modification, and Degradation:

Stephanie Planque, Miguel A. Escobar, Keri C. Smith, Hiroaki Taguchi, Yasuhiro Nishiyama, Elizabeth Donnachie, Kathleen P. Pratt, and Sudhir Paul: Covalent Inactivation of Factor VIII Antibodies from Hemophilia A Patients by an Electrophilic FVIII Analog
J. Biol. Chem. 2008 283: 11876-11886. First Published on March 11, 2008; doi:10.1074/jbc.M800589200 [Abstract] [Full Text] [PDF] [Supplemental Data]

John E. Dominy, Jr., Jesse Hwang, Stephanie Guo, Lawrence L. Hirschberger, Sheng Zhang, and Martha H. Stipanuk: Synthesis of Amino Acid Cofactor in Cysteine Dioxygenase Is Regulated by Substrate and Represents a Novel Post-translational Regulation of Activity
J. Biol. Chem. 2008 283: 12188-12201. First Published on February 28, 2008; doi:10.1074/jbc.M800044200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Genomics, Proteomics, and Bioinformatics:

Yuko Furukawa, Eiji Umemoto, Myoung Ho Jang, Kazuo Tohya, Masayuki Miyasaka, and Takako Hirata: Identification of Novel Isoforms of Mouse L-selectin with Different Carboxyl-terminal Tails
J. Biol. Chem. 2008 283: 12112-12119. First Published on March 10, 2008; doi:10.1074/jbc.M801745200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Protein Structure and Folding:

Jonathan S. Kingsbury, Thomas M. Laue, Elena S. Klimtchuk, Roger Théberge, Catherine E. Costello, and Lawreen H. Connors: The Modulation of Transthyretin Tetramer Stability by Cysteine 10 Adducts and the Drug Diflunisal: DIRECT ANALYSIS BY FLUORESCENCE-DETECTED ANALYTICAL ULTRACENTRIFUGATION
J. Biol. Chem. 2008 283: 11887-11896. First Published on March 6, 2008; doi:10.1074/jbc.M709638200 [Abstract] [Full Text] [PDF]

William J. Valentine, James I. Fells, Donna H. Perygin, Sana Mujahid, Kazuaki Yokoyama, Yuko Fujiwara, Ryoko Tsukahara, James R. Van Brocklyn, Abby L. Parrill, and Gabor Tigyi: Subtype-specific Residues Involved in Ligand Activation of the Endothelial Differentiation Gene Family Lysophosphatidic Acid Receptors
J. Biol. Chem. 2008 283: 12175-12187. First Published on March 3, 2008; doi:10.1074/jbc.M708847200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Jeremiah R. Wagner, Junrui Zhang, David von Stetten, Mina Günther, Daniel H. Murgida, Maria Andrea Mroginski, Joseph M. Walker, Katrina T. Forest, Peter Hildebrandt, and Richard D. Vierstra: Mutational Analysis of Deinococcus radiodurans Bacteriophytochrome Reveals Key Amino Acids Necessary for the Photochromicity and Proton Exchange Cycle of Phytochromes
J. Biol. Chem. 2008 283: 12212-12226. First Published on January 10, 2008; doi:10.1074/jbc.M709355200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Anindito Sen, J. Bernard Heymann, Naiqian Cheng, Jian Qiao, Leonard Mindich, and Alasdair C. Steven: Initial Location of the RNA-dependent RNA Polymerase in the Bacteriophage ${Phi}$ 6 Procapsid Determined by Cryo-electron Microscopy
J. Biol. Chem. 2008 283: 12227-12231. First Published on February 20, 2008; doi:10.1074/jbc.M710508200 [Abstract] [Full Text] [PDF]

Kouhei Tsumoto, Akiko Yokota, Yoshikazu Tanaka, Mihoko Ui, Takeshi Tsumuraya, Ikuo Fujii, Izumi Kumagai, Yoko Nagumo, Hiroki Oguri, Masayuki Inoue, and Masahiro Hirama: Critical Contribution of Aromatic Rings to Specific Recognition of Polyether Rings: THE CASE OF CIGUATOXIN CTX3C-ABC AND ITS SPECIFIC ANTIBODY 1C49
J. Biol. Chem. 2008 283: 12259-12266. First Published on March 6, 2008; doi:10.1074/jbc.M710553200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Amanda J. Fusco, Olga V. Savinova, Rashmi Talwar, Jeffrey D. Kearns, Alexander Hoffmann, and Gourisankar Ghosh: Stabilization of RelB Requires Multidomain Interactions with p100/p52
J. Biol. Chem. 2008 283: 12324-12332. First Published on March 4, 2008; doi:10.1074/jbc.M707898200 [Abstract] [Full Text] [PDF]

Adriana Badarau, Susan J. Firbank, Kevin J. Waldron, Sachiko Yanagisawa, Nigel J. Robinson, Mark J. Banfield, and Christopher Dennison: FutA2 Is a Ferric Binding Protein from Synechocystis PCC 6803
J. Biol. Chem. 2008 283: 12520-12527. First Published on February 4, 2008; doi:10.1074/jbc.M709907200 [Abstract] [Full Text] [PDF]

Enzyme Catalysis and Regulation:

Cristina M. L. Carvalho, Eng-Hui Chew, Seyed Isaac Hashemy, Jun Lu, and Arne Holmgren: Inhibition of the Human Thioredoxin System: A MOLECULAR MECHANISM OF MERCURY TOXICITY
J. Biol. Chem. 2008 283: 11913-11923. First Published on March 4, 2008; doi:10.1074/jbc.M710133200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Malik M. Keshwani and Thomas K. Harris: Kinetic Mechanism of Fully Activated S6K1 Protein Kinase
J. Biol. Chem. 2008 283: 11972-11980. First Published on March 6, 2008; doi:10.1074/jbc.M800114200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Ghassan J. Maghzal, Shane R. Thomas, Nicholas H. Hunt, and Roland Stocker: Cytochrome b₅, Not Superoxide Anion Radical, Is a Major Reductant of Indoleamine 2,3-Dioxygenase in Human Cells
J. Biol. Chem. 2008 283: 12014-12025. First Published on February 25, 2008; doi:10.1074/jbc.M710266200 [Abstract] [Full Text] [PDF]

Hung-Ju Hsu, Keng-Chang Tsai, Yi-Kun Sun, Hung-Ju Chang, Yi-Jen Huang, Hui-Ming Yu, Chun-Hung Lin, Shi-Shan Mao, and An-Suei Yang: Factor Xa Active Site Substrate Specificity with Substrate Phage Display and Computational Molecular Modeling
J. Biol. Chem. 2008 283: 12343-12353. First Published on February 22, 2008; doi:10.1074/jbc.M708843200 [Abstract] [Full Text] [PDF]

Aurelio A. Moya-García, Javier Ruiz-Pernía, Sergio Martí, Francisca Sánchez-Jiménez, and Iñaki Tuñón: Analysis of the Decarboxylation Step in Mammalian Histidine Decarboxylase: A COMPUTATIONAL STUDY
J. Biol. Chem. 2008 283: 12393-12401. First Published on February 29, 2008; doi:10.1074/jbc.M707434200 [Abstract] [Full Text] [PDF]

Katharine A. Sam, Shirley A. Fairhurst, Roger N. F. Thorneley, James W. A. Allen, and Stuart J. Ferguson: Pseudoazurin Dramatically Enhances the Reaction Profile of Nitrite Reduction by Paracoccus pantotrophus Cytochrome cd₁ and Facilitates Release of Product Nitric Oxide
J. Biol. Chem. 2008 283: 12555-12563. First Published on March 2, 2008; doi:10.1074/jbc.M800954200 [Abstract] [Full Text] [PDF]

Metabolism and Bioenergetics:

Hui-Yu Liu, Qu Fan Collins, Fatiha Moukdar, Degen Zhuo, Jianmin Han, Tao Hong, Sheila Collins, and Wenhong Cao: Suppression of Hepatic Glucose Production by Human Neutrophil ${alpha}$ -Defensins through a Signaling Pathway Distinct from Insulin
J. Biol. Chem. 2008 283: 12056-12063. First Published on March 17, 2008; doi:10.1074/jbc.M801033200 [Abstract] [Full Text] [PDF]

Marjatta Son, Scot C. Leary, Nadine Romain, Fabien Pierrel, Dennis R. Winge, Ronald G. Haller, and Jeffrey L. Elliott: Isolated Cytochrome c Oxidase Deficiency in G93A SOD1 Mice Overexpressing CCS Protein
J. Biol. Chem. 2008 283: 12267-12275. First Published on March 11, 2008; doi:10.1074/jbc.M708523200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Glycobiology and Extracellular Matrices:

Sally M. Humphries, Yinhui Lu, Elizabeth G. Canty, and Karl E. Kadler: Active Negative Control of Collagen Fibrillogenesis in Vivo: INTRACELLULAR CLEAVAGE OF THE TYPE I PROCOLLAGEN PROPEPTIDES IN TENDON FIBROBLASTS WITHOUT INTRACELLULAR FIBRILS
J. Biol. Chem. 2008 283: 12129-12135. First Published on February 19, 2008; doi:10.1074/jbc.M708198200 [Abstract] [Full Text] [PDF]

Shuguang Bi, Lesley A. Earl, Linsey Jacobs, and Linda G. Baum: Structural Features of Galectin-9 and Galectin-1 That Determine Distinct T Cell Death Pathways
J. Biol. Chem. 2008 283: 12248-12258. First Published on February 7, 2008; doi:10.1074/jbc.M800523200 [Abstract] [Full Text] [PDF]

Brian Bae, Samuel Ohene-Adjei, Svetlana Kocherginskaya, Roderick I. Mackie, M. Ashley Spies, Isaac K. O. Cann, and Satish K. Nair: Molecular Basis for the Selectivity and Specificity of Ligand Recognition by the Family 16 Carbohydrate-binding Modules from Thermoanaerobacterium polysaccharolyticum ManA
J. Biol. Chem. 2008 283: 12415-12425. First Published on November 19, 2007; doi:10.1074/jbc.M706513200 [Abstract] [Full Text] [PDF]

Katie J. Gregg, Ron Finn, D. Wade Abbott, and Alisdair B. Boraston: Divergent Modes of Glycan Recognition by a New Family of Carbohydrate-binding Modules
J. Biol. Chem. 2008 283: 12604-12613. First Published on February 21, 2008; doi:10.1074/jbc.M709865200 [Abstract] [Full Text] [PDF] [Supplemental Data] [Summary]

Yasuo Yoshida, Jinghua Yang, Paule-Esther Peaker, Hirohisa Kato, C. Allen Bush, and John O. Cisar: Molecular and Antigenic Characterization of a Streptococcus oralis Coaggregation Receptor Polysaccharide by Carbohydrate Engineering in Streptococcus gordonii
J. Biol. Chem. 2008 283: 12654-12664. First Published on February 25, 2008; doi:10.1074/jbc.M801412200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Lipids and Lipoproteins: Metabolism, Regulation, and Signaling:

Anne M. Martin, Christoph Kuhlmann, Svenja Trossbach, Sebastian Jaeger, Elaine Waldron, Anton Roebroek, Heiko J. Luhmann, Alexander Laatsch, Sascha Weggen, Volkmar Lessmann, and Claus U. Pietrzik: The Functional Role of the Second NPXY Motif of the LRP1 β-Chain in Tissue-type Plasminogen Activator-mediated Activation of N-Methyl-D-aspartate Receptors
J. Biol. Chem. 2008 283: 12004-12013. First Published on March 5, 2008; doi:10.1074/jbc.M707607200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Joshua D. Brooks, Ginger L. Milne, Huiyong Yin, Stephanie C. Sanchez, Ned A. Porter, and Jason D. Morrow: Formation of Highly Reactive Cyclopentenone Isoprostane Compounds (A₃/J₃-Isoprostanes) in Vivo from Eicosapentaenoic Acid
J. Biol. Chem. 2008 283: 12043-12055. First Published on February 10, 2008; doi:10.1074/jbc.M800122200 [Abstract] [Full Text] [PDF]

Ines M. Macias-Perez, Roy Zent, Monica Carmosino, Matthew D. Breyer, Richard M. Breyer, and Ambra Pozzi: Mouse EP3 ${alpha}$ , β, and ${gamma}$ Receptor Variants Reduce Tumor Cell Proliferation and Tumorigenesis in Vivo
J. Biol. Chem. 2008 283: 12538-12545. First Published on January 29, 2008; doi:10.1074/jbc.M800105200 [Abstract] [Full Text] [PDF]

Membrane Transport, Structure, Function, and Biogenesis:

Min Lu, Fernando Echeverri, Dalia Kalabat, Bianca Laita, David S. Dahan, Raymond D. Smith, Hong Xu, Lena Staszewski, Jeff Yamamoto, Jing Ling, Nancy Hwang, Rachel Kimmich, Peter Li, Erika Patron, Walter Keung, Andrew Patron, and Bryan D. Moyer: Small Molecule Activator of the Human Epithelial Sodium Channel
J. Biol. Chem. 2008 283: 11981-11994. First Published on March 6, 2008; doi:10.1074/jbc.M708001200 [Abstract] [Full Text] [PDF]

Daejong Jeon, Inseon Song, William Guido, Karam Kim, Eunjoon Kim, Uhtaek Oh, and Hee-Sup Shin: Ablation of Ca²⁺ Channel β3 Subunit Leads to Enhanced N-Methyl-D-aspartate Receptor-dependent Long Term Potentiation and Improved Long Term Memory
J. Biol. Chem. 2008 283: 12093-12101. First Published on March 13, 2008; doi:10.1074/jbc.M800816200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Eileen M. Kelly, Zhanjia Hou, Julie Bossuyt, Donald M. Bers, and Seth L. Robia: Phospholamban Oligomerization, Quaternary Structure, and Sarco(endo)plasmic Reticulum Calcium ATPase Binding Measured by Fluorescence Resonance Energy Transfer in Living Cells
J. Biol. Chem. 2008 283: 12202-12211. First Published on February 19, 2008; doi:10.1074/jbc.M707590200 [Abstract] [Full Text] [PDF]

Masayuki Tanemoto, Takafumi Toyohara, Takaaki Abe, and Sadayoshi Ito: MAGI-1a Functions as a Scaffolding Protein for the Distal Renal Tubular Basolateral K⁺ Channels
J. Biol. Chem. 2008 283: 12241-12247. First Published on February 26, 2008; doi:10.1074/jbc.M707738200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Yael Elbaz, Tal Salomon, and Shimon Schuldiner: Identification of a Glycine Motif Required for Packing in EmrE, a Multidrug Transporter from Escherichia coli
J. Biol. Chem. 2008 283: 12276-12283. First Published on March 5, 2008; doi:10.1074/jbc.M710338200 [Abstract] [Full Text] [PDF]

Zhou Zhang, Armanda Gameiro, and Christof Grewer: Highly Conserved Asparagine 82 Controls the Interaction of Na⁺ with the Sodium-coupled Neutral Amino Acid Transporter SNAT2
J. Biol. Chem. 2008 283: 12284-12292. First Published on March 4, 2008; doi:10.1074/jbc.M706774200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Tatyana Romantsov, Leanne Stalker, Doreen E. Culham, and Janet M. Wood: Cardiolipin Controls the Osmotic Stress Response and the Subcellular Location of Transporter ProP in Escherichia coli
J. Biol. Chem. 2008 283: 12314-12323. First Published on March 7, 2008; doi:10.1074/jbc.M709871200 [Abstract] [Full Text] [PDF] [Supplemental Data]

P. Ryan Steed and Robert H. Fillingame: Subunit a Facilitates Aqueous Access to a Membrane-embedded Region of Subunit c in Escherichia coli F₁F₀ ATP Synthase
J. Biol. Chem. 2008 283: 12365-12372. First Published on March 10, 2008; doi:10.1074/jbc.M800901200 [Abstract] [Full Text] [PDF]

Hans C. Zaun, Alvin Shrier, and John Orlowski: Calcineurin B Homologous Protein 3 Promotes the Biosynthetic Maturation, Cell Surface Stability, and Optimal Transport of the Na⁺/H⁺ Exchanger NHE1 Isoform
J. Biol. Chem. 2008 283: 12456-12467. First Published on March 5, 2008; doi:10.1074/jbc.M800267200 [Abstract] [Full Text] [PDF]

Xiao Mei Song, Richard C. Hresko, and Mike Mueckler: Identification of Amino Acid Residues within the C Terminus of the Glut4 Glucose Transporter That Are Essential for Insulin-stimulated Redistribution to the Plasma Membrane
J. Biol. Chem. 2008 283: 12571-12585. First Published on February 27, 2008; doi:10.1074/jbc.M800838200 [Abstract] [Full Text] [PDF]

Claire Hastie, John R. Masters, Stephen E. Moss, and Soren Naaby-Hansen: Interferon- ${gamma}$ Reduces Cell Surface Expression of Annexin 2 and Suppresses the Invasive Capacity of Prostate Cancer Cells
J. Biol. Chem. 2008 283: 12595-12603. First Published on January 22, 2008; doi:10.1074/jbc.M800189200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Christine Chiaverini, Laurent Beuret, Enrica Flori, Roser Busca, Patricia Abbe, Karine Bille, Philippe Bahadoran, Jean-Paul Ortonne, Corine Bertolotto, and Robert Ballotti: Microphthalmia-associated Transcription Factor Regulates RAB27A Gene Expression and Controls Melanosome Transport
J. Biol. Chem. 2008 283: 12635-12642. First Published on February 15, 2008; doi:10.1074/jbc.M800130200 [Abstract] [Full Text] [PDF]

Molecular Basis Of Cell and Developmental Biology:

Bin Zhang, Yuanlin Dong, Guohua Zhang, Robert D. Moir, Weiming Xia, Yun Yue, Ming Tian, Deborah J. Culley, Gregory Crosby, Rudolph E. Tanzi, and Zhongcong Xie: The Inhalation Anesthetic Desflurane Induces Caspase Activation and Increases Amyloid β-Protein Levels under Hypoxic Conditions
J. Biol. Chem. 2008 283: 11866-11875. First Published on March 6, 2008; doi:10.1074/jbc.M800199200 [Abstract] [Full Text] [PDF]

Adele R. Gordon, Susan V. Outram, Mohammad Keramatipour, Catherine A. Goddard, William H. Colledge, James C. Metcalfe, Ariadne L. Hager-Theodorides, Tessa Crompton, and Paul R. Kemp: Splenomegaly and Modified Erythropoiesis in KLF13^–/– Mice
J. Biol. Chem. 2008 283: 11897-11904. First Published on February 19, 2008; doi:10.1074/jbc.M709569200 [Abstract] [Full Text] [PDF]

Jaehak Oh, Dong H. Sohn, Myunggon Ko, Heekyoung Chung, Sung H. Jeon, and Rho H. Seong: BAF60a Interacts with p53 to Recruit the SWI/SNF Complex
J. Biol. Chem. 2008 283: 11924-11934. First Published on February 26, 2008; doi:10.1074/jbc.M705401200 [Abstract] [Full Text] [PDF]

Aya Iriyama, Ryoji Fujiki, Yuji Inoue, Hidenori Takahashi, Yasuhiro Tamaki, Shinichiro Takezawa, Kenichi Takeyama, Woo-Dong Jang, Shigeaki Kato, and Yasuo Yanagi: A2E, a Pigment of the Lipofuscin of Retinal Pigment Epithelial Cells, Is an Endogenous Ligand for Retinoic Acid Receptor
J. Biol. Chem. 2008 283: 11947-11953. First Published on March 6, 2008; doi:10.1074/jbc.M708989200 [Abstract] [Full Text] [PDF]

Masahumi Kawaguchi, Tomoko Toyama, Ryosuke Kaneko, Teruyoshi Hirayama, Yoshimi Kawamura, and Takeshi Yagi: Relationship between DNA Methylation States and Transcription of Individual Isoforms Encoded by the Protocadherin- ${alpha}$ Gene Cluster
J. Biol. Chem. 2008 283: 12064-12075. First Published on January 18, 2008; doi:10.1074/jbc.M709648200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Su Yeon Shim, Benjamin Adam Samuels, Jian Wang, Gernot Neumayer, Camille Belzil, Ramses Ayala, Yang Shi, Yujiang Shi, Li-Huei Tsai, and Minh Dang Nguyen: Ndel1 Controls the Dynein-mediated Transport of Vimentin during Neurite Outgrowth
J. Biol. Chem. 2008 283: 12232-12240. First Published on February 26, 2008; doi:10.1074/jbc.M710200200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Mariano G. Buffone, Tiangang Zhuang, Teri S. Ord, Ling Hui, Stuart B. Moss, and George L. Gerton: Recombinant Mouse Sperm ZP3-binding Protein (ZP3R/sp56) Forms a High Order Oligomer That Binds Eggs and Inhibits Mouse Fertilization in Vitro
J. Biol. Chem. 2008 283: 12438-12445. First Published on March 3, 2008; doi:10.1074/jbc.M706421200 [Abstract] [Full Text] [PDF]

Cheng-Fen Tu, Yu-Ting Yan, Szu-Yao Wu, Bambang Djoko, Ming-Tzu Tsai, Chien-Jui Cheng, and Ruey-Bing Yang: Domain and Functional Analysis of a Novel Platelet-Endothelial Cell Surface Protein, SCUBE1
J. Biol. Chem. 2008 283: 12478-12488. First Published on February 26, 2008; doi:10.1074/jbc.M705872200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Hui Chen, Xiaojuan He, Zhun Wang, Di Wu, Huiyuan Zhang, Chunping Xu, Hongbin He, Lianxian Cui, Denian Ba, and Wei He: Identification of Human T Cell Receptor ${gamma}$ ${delta}$ -recognized Epitopes/Proteins via CDR3 ${delta}$ Peptide-based Immunobiochemical Strategy
J. Biol. Chem. 2008 283: 12528-12537. First Published on March 5, 2008; doi:10.1074/jbc.M708067200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Zhousheng Xiao, Shiqin Zhang, Brenda S. Magenheimer, Junming Luo, and L. Darryl Quarles: Polycystin-1 Regulates Skeletogenesis through Stimulation of the Osteoblast-specific Transcription Factor RUNX2-II
J. Biol. Chem. 2008 283: 12624-12634. First Published on March 5, 2008; doi:10.1074/jbc.M710407200 [Abstract] [Full Text] [PDF]

Amlan Das, Christine Base, Debasis Manna, Wonhwa Cho, and Ronald R. Dubreuil: Unexpected Complexity in the Mechanisms That Target Assembly of the Spectrin Cytoskeleton
J. Biol. Chem. 2008 283: 12643-12653. First Published on February 19, 2008; doi:10.1074/jbc.M800094200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Tao Wang and Elizabeth A. Craig: Binding of Yeast Frataxin to the Scaffold for Fe-S Cluster Biogenesis, Isu
J. Biol. Chem. 2008 283: 12674-12679. First Published on March 4, 2008; doi:10.1074/jbc.M800399200 [Abstract] [Full Text] [PDF]

Mechanisms Of Signal Transduction:

Dianhong Luo, Yun He, Haifeng Zhang, Luyang Yu, Hong Chen, Zhe Xu, Shibo Tang, Fumihiko Urano, and Wang Min: AIP1 Is Critical in Transducing IRE1-mediated Endoplasmic Reticulum Stress Response
J. Biol. Chem. 2008 283: 11905-11912. First Published on February 15, 2008; doi:10.1074/jbc.M710557200 [Abstract] [Full Text] [PDF]

Christopher Kable Means, Shigeki Miyamoto, Jerold Chun, and Joan Heller Brown: S1P₁ Receptor Localization Confers Selectivity for G_i-mediated cAMP and Contractile Responses
J. Biol. Chem. 2008 283: 11954-11963. First Published on February 24, 2008; doi:10.1074/jbc.M707422200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Sebastien Jacquet, Yasuhiro Nishino, Sarawut Kumphune, Pierre Sicard, James E. Clark, Koichi S. Kobayashi, Richard A. Flavell, Jan Eickhoff, Matt Cotten, and Michael S. Marber: The Role of RIP2 in p38 MAPK Activation in the Stressed Heart
J. Biol. Chem. 2008 283: 11964-11971. First Published on February 29, 2008; doi:10.1074/jbc.M707750200 [Abstract] [Full Text] [PDF]

Zubair A. Karim, Wangsun Choi, and Sidney W. Whiteheart: Primary Platelet Signaling Cascades and Integrin-mediated Signaling Control ADP-ribosylation Factor (Arf) 6-GTP Levels during Platelet Activation and Aggregation
J. Biol. Chem. 2008 283: 11995-12003. First Published on March 7, 2008; doi:10.1074/jbc.M800146200 [Abstract] [Full Text] [PDF]

Rahim Abdulhussein, Diana H. H. Koo, and Wolfgang F. Vogel: Identification of Disulfide-linked Dimers of the Receptor Tyrosine Kinase DDR1
J. Biol. Chem. 2008 283: 12026-12033. First Published on December 7, 2007; doi:10.1074/jbc.M704592200 [Abstract] [Full Text] [PDF]

Blazej Dolniak, Efstratios Katsoulidis, Nathalie Carayol, Jessica K. Altman, Amanda J. Redig, Martin S. Tallman, Takeshi Ueda, Rie Watanabe-Fukunaga, Rikiro Fukunaga, and Leonidas C. Platanias: Regulation of Arsenic Trioxide-induced Cellular Responses by Mnk1 and Mnk2
J. Biol. Chem. 2008 283: 12034-12042. First Published on February 25, 2008; doi:10.1074/jbc.M708816200 [Abstract] [Full Text] [PDF]

Xiaojian Wang, Bin Liu, Nan Li, Hongzhe Li, Jianming Qiu, Yuanyuan Zhang, and Xuetao Cao: IPP5, a Novel Protein Inhibitor of Protein Phosphatase 1, Promotes G₁/S Progression in a Thr-40-dependent Manner
J. Biol. Chem. 2008 283: 12076-12084. First Published on February 29, 2008; doi:10.1074/jbc.M801571200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Elke Hoffmann, Judith Ashouri, Sabine Wolter, Anneke Doerrie, Oliver Dittrich-Breiholz, Heike Schneider, Erwin F. Wagner, Jakob Troppmair, Nigel Mackman, and Michael Kracht: Transcriptional Regulation of EGR-1 by the Interleukin-1-JNK-MKK7-c-Jun Pathway
J. Biol. Chem. 2008 283: 12120-12128. First Published on February 15, 2008; doi:10.1074/jbc.M800583200 [Abstract] [Full Text] [PDF]

Pablo Mardones, Juan F. Medina, and Ronald P. J. Oude Elferink: Activation of Cyclic AMP Signaling in Ae2-deficient Mouse Fibroblasts
J. Biol. Chem. 2008 283: 12146-12153. First Published on March 4, 2008; doi:10.1074/jbc.M710590200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Andrew J. Ramsay, Ying Dong, Melanie L. Hunt, MayLa Linn, Hemamali Samaratunga, Judith A. Clements, and John D. Hooper: Kallikrein-related Peptidase 4 (KLK4) Initiates Intracellular Signaling via Protease-activated Receptors (PARs): KLK4 AND PAR-2 ARE CO-EXPRESSED DURING PROSTATE CANCER PROGRESSION
J. Biol. Chem. 2008 283: 12293-12304. First Published on February 28, 2008; doi:10.1074/jbc.M709493200 [Abstract] [Full Text] [PDF]

Andrea Havasi, Zhijian Li, Zhiyong Wang, Jody L. Martin, Venugopal Botla, Kathleen Ruchalski, John H. Schwartz, and Steven C. Borkan: Hsp27 Inhibits Bax Activation and Apoptosis via a Phosphatidylinositol 3-Kinase-dependent Mechanism
J. Biol. Chem. 2008 283: 12305-12313. First Published on February 25, 2008; doi:10.1074/jbc.M801291200 [Abstract] [Full Text] [PDF]

Antoaneta Belcheva and Dasantila Golemi-Kotra: A Close-up View of the VraSR Two-component System: A MEDIATOR OF STAPHYLOCOCCUS AUREUS RESPONSE TO CELL WALL DAMAGE
J. Biol. Chem. 2008 283: 12354-12364. First Published on March 7, 2008; doi:10.1074/jbc.M710010200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Martha Zentella de Piña, Héctor Vázquez-Meza, Juan Pablo Pardo, Juan Luis Rendón, Rafael Villalobos-Molina, Héctor Riveros-Rosas, and Enrique Piña: Signaling the Signal, Cyclic AMP-dependent Protein Kinase Inhibition by Insulin-formed H₂O₂ and Reactivation by Thioredoxin
J. Biol. Chem. 2008 283: 12373-12386. First Published on March 6, 2008; doi:10.1074/jbc.M706832200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Xiao-Xin Sun, Mu-Shui Dai, and Hua Lu: Mycophenolic Acid Activation of p53 Requires Ribosomal Proteins L5 and L11
J. Biol. Chem. 2008 283: 12387-12392. First Published on February 27, 2008; doi:10.1074/jbc.M801387200 [Abstract] [Full Text] [PDF]

Ping Song, Zhonglin Xie, Yong Wu, Jian Xu, Yunzhou Dong, and Ming-Hui Zou: Protein Kinase C ${zeta}$ -dependent LKB1 Serine 428 Phosphorylation Increases LKB1 Nucleus Export and Apoptosis in Endothelial Cells
J. Biol. Chem. 2008 283: 12446-12455. First Published on March 5, 2008; doi:10.1074/jbc.M708208200 [Abstract] [Full Text] [PDF]

Guang Yan, Jiannan Huang, Nancy Ruth Jarbadan, Yixing Jiang, and Hua Cheng: Sequestration of NF- ${kappa}$ B Signaling Complexes in Lipid Rafts Contributes to Repression of NF- ${kappa}$ B in T Lymphocytes under Hyperthermia Stress
J. Biol. Chem. 2008 283: 12489-12500. First Published on March 3, 2008; doi:10.1074/jbc.M707988200 [Abstract] [Full Text] [PDF]

Yeddula Narayana and Kithiganahalli Narayanaswamy Balaji: NOTCH1 Up-regulation and Signaling Involved in Mycobacterium bovis BCG-induced SOCS3 Expression in Macrophages
J. Biol. Chem. 2008 283: 12501-12511. First Published on March 10, 2008; doi:10.1074/jbc.M709960200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Sepehr Dadsetan, Liudmila Zakharova, Tadeusz F. Molinski, and Alla F. Fomina: Store-operated Ca²⁺ Influx Causes Ca²⁺ Release from the Intracellular Ca²⁺ Channels That Is Required for T Cell Activation
J. Biol. Chem. 2008 283: 12512-12519. First Published on March 3, 2008; doi:10.1074/jbc.M709330200 [Abstract] [Full Text] [PDF]

Tomoaki Koga, Jae Hyang Lim, Hirofumi Jono, Un Hwan Ha, Haidong Xu, Hajime Ishinaga, Saori Morino, Xiangbin Xu, Chen Yan, Hirofumi Kai, and Jian-Dong Li: Tumor Suppressor Cylindromatosis Acts as a Negative Regulator for Streptococcus pneumoniae-induced NFAT Signaling
J. Biol. Chem. 2008 283: 12546-12554. First Published on March 10, 2008; doi:10.1074/jbc.M710518200 [Abstract] [Full Text] [PDF]

Gopa Biswas, Weigang Tang, Neal Sondheimer, Manti Guha, Seema Bansal, and Narayan G. Avadhani: A Distinctive Physiological Role for I ${kappa}$ Bβ in the Propagation of Mitochondrial Respiratory Stress Signaling
J. Biol. Chem. 2008 283: 12586-12594. First Published on February 13, 2008; doi:10.1074/jbc.M710481200 [Abstract] [Full Text] [PDF]

Additions and Corrections:

Pascal Kienlen-Campard, Bernadette Tasiaux, Joanne Van Hees, Mingli Li, Sandra Huysseune, Takeshi Sato, Jeffrey Z. Fei, Saburo Aimoto, Pierre J. Courtoy, Steven O. Smith, Stefan N. Constantinescu, and Jean-Noël Octave: Amyloidogenic processing but not amyloid precursor protein (APP) intracellular C-terminal domain production requires a precisely oriented APP dimer assembled by transmembrane GXXXG motifs. VOLUME 283 (2008) PAGES 7733-7744
J. Biol. Chem. 2008 283: 12680. [Full Text] [PDF]

Adriana Y. Sierra, Esther Gratacós, Patricia Carrasco, Josep Clotet, Jesús Ureña, Dolors Serra, Guillermina Asins, Fausto G. Hegardt, and Núria Casals: CPT1c is localized in endoplasmic reticulum of neurons and has carnitine palmitoyltransferase activity. VOLUME 283 (2008) PAGES 6878-6885
J. Biol. Chem. 2008 283: 12680-a. [Full Text] [PDF]