JBC -- Table of Contents (May 9 2008, 283, (19))

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Classics:

Nicole Kresge, Robert D. Simoni, and Robert L. Hill: Developing the Purine Nucleoside Analogue Acyclovir: the Work of Gertrude B. Elion
Thymidine kinase from herpes simplex virus phosphorylates the new antiviral compound, 9-(2-hydroxyethoxymethyl)guanine (J. A. Fyfe, P. M. Keller, P. A. Furman, R. L. Miller, and G. B. Elion J. Biol. Chem.253, 8721-8727)
Inhibition of purified human and herpes simplex virus-induced DNA polymerases by 9-(2-hydroxyethoxymethyl)guanine triphosphate. Effects on primer-template function (D Derse, YC Cheng, PA Furman, MH St. Clair, and GB Elion J. Biol. Chem.256, 11447-11451)
J. Biol. Chem. 2008 283: e11. [Full Text]

Accelerated Publications:

Susanne Radke, Harish Chander, Patrick Schäfer, Gregor Meiss, Rejko Krüger, Jörg B. Schulz, and Doris Germain: Mitochondrial Protein Quality Control by the Proteasome Involves Ubiquitination and the Protease Omi
J. Biol. Chem. 2008 283: 12681-12685. First Published on March 24, 2008; doi:10.1074/jbc.C800036200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Yu Li, Xiaowu Zhang, Roberto D. Polakiewicz, Tso-Pang Yao, and Michael J. Comb: HDAC6 Is Required for Epidermal Growth Factor-induced β-Catenin Nuclear Localization
J. Biol. Chem. 2008 283: 12686-12690. First Published on March 20, 2008; doi:10.1074/jbc.C700185200 [Abstract] [Full Text] [PDF]

DNA: Replication, Repair, Recombination, and Chromosome Dynamics:

Yanbin Zhang, Fenghua Yuan, Daojing Wang, Liya Gu, and Guo-Min Li: Identification of Regulatory Factor X as a Novel Mismatch Repair Stimulatory Factor
J. Biol. Chem. 2008 283: 12730-12735. First Published on March 4, 2008; doi:10.1074/jbc.M800460200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Silvia Tornaletti, Shaun Park-Snyder, and Philip C. Hanawalt: G4-forming Sequences in the Non-transcribed DNA Strand Pose Blocks to T7 RNA Polymerase and Mammalian RNA Polymerase II
J. Biol. Chem. 2008 283: 12756-12762. First Published on February 20, 2008; doi:10.1074/jbc.M705003200 [Abstract] [Full Text] [PDF]

Gary M. Riefler, Sharon Y. R. Dent, and Jill M. Schumacher: Tousled-mediated Activation of Aurora B Kinase Does Not Require Tousled Kinase Activity in Vivo
J. Biol. Chem. 2008 283: 12763-12768. First Published on March 10, 2008; doi:10.1074/jbc.M709034200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Ravi R. Iyer, Timothy J. Pohlhaus, Sihong Chen, Gregory L. Hura, Leonid Dzantiev, Lorena S. Beese, and Paul Modrich: The MutS ${alpha}$ -Proliferating Cell Nuclear Antigen Interaction in Human DNA Mismatch Repair
J. Biol. Chem. 2008 283: 13310-13319. First Published on March 7, 2008; doi:10.1074/jbc.M800606200 [Abstract] [Full Text] [PDF] [Supplemental Data] [Summary]

Emmanuelle Delagoutte, Geoffrey M. Goellner, Jie Guo, Giuseppe Baldacci, and Cynthia T. McMurray: Single-stranded DNA-binding Protein in Vitro Eliminates the Orientation-dependent Impediment to Polymerase Passage on CAG/CTG Repeats
J. Biol. Chem. 2008 283: 13341-13356. First Published on February 8, 2008; doi:10.1074/jbc.M800153200 [Abstract] [Full Text] [PDF]

Transcription, Chromatin, and Epigenetics:

Chengjian Mao, Nicole M. Patterson, Milu T. Cherian, Irene O. Aninye, Chen Zhang, Jamie Bonéy Montoya, Jingwei Cheng, Karson S. Putt, Paul J. Hergenrother, Elizabeth M. Wilson, Ann M. Nardulli, Steven K. Nordeen, and David J. Shapiro: A New Small Molecule Inhibitor of Estrogen Receptor ${alpha}$ Binding to Estrogen Response Elements Blocks Estrogen-dependent Growth of Cancer Cells
J. Biol. Chem. 2008 283: 12819-12830. First Published on March 12, 2008; doi:10.1074/jbc.M709936200 [Abstract] [Full Text] [PDF]

Hui Li, Padmaja Gade, Shreeram C. Nallar, Abhijit Raha, Sanjit K. Roy, Sreenivasu Karra, Janardan K. Reddy, Sekhar P. Reddy, and Dhananjaya V. Kalvakolanu: The Med1 Subunit of Transcriptional Mediator Plays a Central Role in Regulating CCAAT/Enhancer-binding Protein-β-driven Transcription in Response to Interferon- ${gamma}$
J. Biol. Chem. 2008 283: 13077-13086. First Published on March 12, 2008; doi:10.1074/jbc.M800604200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Seok-Geun Lee, Zhao-Zhong Su, Luni Emdad, Pankaj Gupta, Devanand Sarkar, Alejandra Borjabad, David J. Volsky, and Paul B. Fisher: Mechanism of Ceftriaxone Induction of Excitatory Amino Acid Transporter-2 Expression and Glutamate Uptake in Primary Human Astrocytes
J. Biol. Chem. 2008 283: 13116-13123. First Published on March 7, 2008; doi:10.1074/jbc.M707697200 [Abstract] [Full Text] [PDF]

Yuko Ogo, Takanori Kobayashi, Reiko Nakanishi Itai, Hiromi Nakanishi, Yusuke Kakei, Michiko Takahashi, Seiichi Toki, Satoshi Mori, and Naoko K. Nishizawa: A Novel NAC Transcription Factor, IDEF2, That Recognizes the Iron Deficiency-responsive Element 2 Regulates the Genes Involved in Iron Homeostasis in Plants
J. Biol. Chem. 2008 283: 13407-13417. First Published on February 28, 2008; doi:10.1074/jbc.M708732200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Eyal Jacob, Reut Hod-Dvorai, Sagie Schif-Zuck, and Orly Avni: Unconventional Association of the Polycomb Group Proteins with Cytokine Genes in Differentiated T Helper Cells
J. Biol. Chem. 2008 283: 13471-13481. First Published on February 19, 2008; doi:10.1074/jbc.M709886200 [Abstract] [Full Text] [PDF]

RNA: Processing and Catalysis:

Allison Lange, Ryan E. Mills, Scott E. Devine, and Anita H. Corbett: A PY-NLS Nuclear Targeting Signal Is Required for Nuclear Localization and Function of the Saccharomyces cerevisiae mRNA-binding Protein Hrp1
J. Biol. Chem. 2008 283: 12926-12934. First Published on March 14, 2008; doi:10.1074/jbc.M800898200 [Abstract] [Full Text] [PDF]

Ana Barbas, Rute G. Matos, Mónica Amblar, Eduardo López-Viñas, Paulino Gomez-Puertas, and Cecília M. Arraiano: New Insights into the Mechanism of RNA Degradation by Ribonuclease II: IDENTIFICATION OF THE RESIDUE RESPONSIBLE FOR SETTING THE RNase II END PRODUCT
J. Biol. Chem. 2008 283: 13070-13076. First Published on March 12, 2008; doi:10.1074/jbc.M709989200 [Abstract] [Full Text] [PDF] [Supplemental Data]

RNA-Mediated Regulation and Noncoding RNAs:

Yu Wang, Alvin T. C. Lee, Joel Z. I. Ma, Jingbo Wang, Jianwei Ren, Yuchen Yang, Erwin Tantoso, Kuo-Bin Li, London L. P. J Ooi, Patrick Tan, and Caroline G. L. Lee: Profiling MicroRNA Expression in Hepatocellular Carcinoma Reveals MicroRNA-224 Up-regulation and Apoptosis Inhibitor-5 as a MicroRNA-224-specific Target
J. Biol. Chem. 2008 283: 13205-13215. First Published on March 4, 2008; doi:10.1074/jbc.M707629200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Protein Synthesis, Post-Translational Modification, and Degradation:

Kevin A. Glenn, Rick F. Nelson, Hsiang M. Wen, Adam J. Mallinger, and Henry L. Paulson: Diversity in Tissue Expression, Substrate Binding, and SCF Complex Formation for a Lectin Family of Ubiquitin Ligases
J. Biol. Chem. 2008 283: 12717-12729. First Published on January 18, 2008; doi:10.1074/jbc.M709508200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Omar A. Bazirgan and Randolph Y. Hampton: Cue1p Is an Activator of Ubc7p E2 Activity in Vitro and in Vivo
J. Biol. Chem. 2008 283: 12797-12810. First Published on March 5, 2008; doi:10.1074/jbc.M801122200 [Abstract] [Full Text] [PDF]

Dao-Yao He and Dorit Ron: Glial Cell Line-derived Neurotrophic Factor Reverses Ethanol-mediated Increases in Tyrosine Hydroxylase Immunoreactivity via Altering the Activity of Heat Shock Protein 90
J. Biol. Chem. 2008 283: 12811-12818. First Published on March 14, 2008; doi:10.1074/jbc.M706216200 [Abstract] [Full Text] [PDF]

Marcus W. Brazier, Paul Davies, Esmie Player, Frank Marken, John H. Viles, and David R. Brown: Manganese Binding to the Prion Protein
J. Biol. Chem. 2008 283: 12831-12839. First Published on March 10, 2008; doi:10.1074/jbc.M709820200 [Abstract] [Full Text] [PDF]

Mark E. Drew, Ritu Banerjee, Eric W. Uffman, Scott Gilbertson, Philip J. Rosenthal, and Daniel E. Goldberg: Plasmodium Food Vacuole Plasmepsins Are Activated by Falcipains
J. Biol. Chem. 2008 283: 12870-12876. First Published on February 28, 2008; doi:10.1074/jbc.M708949200 [Abstract] [Full Text] [PDF]

Gregory Pratt and Martin Rechsteiner: Proteasomes Cleave at Multiple Sites within Polyglutamine Tracts: ACTIVATION BY PA28 ${gamma}$ (K188E)
J. Biol. Chem. 2008 283: 12919-12925. First Published on March 13, 2008; doi:10.1074/jbc.M709347200 [Abstract] [Full Text] [PDF]

Yong-Gang Chang, Xian-Zhong Yan, Yuan-Yuan Xie, Xue-Chao Gao, Ai-Xin Song, Dong-Er Zhang, and Hong-Yu Hu: Different Roles for Two Ubiquitin-like Domains of ISG15 in Protein Modification
J. Biol. Chem. 2008 283: 13370-13377. First Published on March 20, 2008; doi:10.1074/jbc.M800162200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Sandra Loch, Florian Klauschies, Christian Schölz, Marieke C. Verweij, Emmanuel J. H. J. Wiertz, Joachim Koch, and Robert Tampé: Signaling of a Varicelloviral Factor across the Endoplasmic Reticulum Membrane Induces Destruction of the Peptide-loading Complex and Immune Evasion
J. Biol. Chem. 2008 283: 13428-13436. First Published on March 5, 2008; doi:10.1074/jbc.M800226200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Protein Structure and Folding:

Wei Xing Yan, Chris Armishaw, Jesse Goyette, Zheng Yang, Hong Cai, Paul Alewood, and Carolyn L. Geczy: Mast Cell and Monocyte Recruitment by S100A12 and Its Hinge Domain
J. Biol. Chem. 2008 283: 13035-13043. First Published on February 21, 2008; doi:10.1074/jbc.M710388200 [Abstract] [Full Text] [PDF]

Ryuichiro Suzuki, Jun Wada, Takane Katayama, Shinya Fushinobu, Takayoshi Wakagi, Hirofumi Shoun, Hayuki Sugimoto, Akiyoshi Tanaka, Hidehiko Kumagai, Hisashi Ashida, Motomitsu Kitaoka, and Kenji Yamamoto: Structural and Thermodynamic Analyses of Solute-binding Protein from Bifidobacterium longum Specific for Core 1 Disaccharide and Lacto-N-biose I
J. Biol. Chem. 2008 283: 13165-13173. First Published on March 10, 2008; doi:10.1074/jbc.M709777200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Li Liu, Rajani Srikakulam, and Donald A. Winkelmann: Unc45 Activates Hsp90-dependent Folding of the Myosin Motor Domain
J. Biol. Chem. 2008 283: 13185-13193. First Published on March 7, 2008; doi:10.1074/jbc.M800757200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Pascale Aliprandi, Christina Sizun, Javier Perez, Fabien Mareuil, Sandrine Caputo, Jean-Louis Leroy, Benoît Odaert, Soumaya Laalami, Marc Uzan, and François Bontems: S1 Ribosomal Protein Functions in Translation Initiation and Ribonuclease RegB Activation Are Mediated by Similar RNA-Protein Interactions: AN NMR AND SAXS ANALYSIS
J. Biol. Chem. 2008 283: 13289-13301. First Published on January 22, 2008; doi:10.1074/jbc.M707111200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Karolina Michalska, Alejandra Hernandez-Santoyo, and Mariusz Jaskolski: The Mechanism of Autocatalytic Activation of Plant-type L-Asparaginases
J. Biol. Chem. 2008 283: 13388-13397. First Published on March 10, 2008; doi:10.1074/jbc.M800746200 [Abstract] [Full Text] [PDF]

Jane M. Sayer, Fengling Liu, Rieko Ishima, Irene T. Weber, and John M. Louis: Effect of the Active Site D25N Mutation on the Structure, Stability, and Ligand Binding of the Mature HIV-1 Protease
J. Biol. Chem. 2008 283: 13459-13470. First Published on February 15, 2008; doi:10.1074/jbc.M708506200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Enzyme Catalysis and Regulation:

Sandrine Lemaire, Cosimo Fuda, Françoise Van Bambeke, Paul M. Tulkens, and Shahriar Mobashery: Restoration of Susceptibility of Methicillin-resistant Staphylococcus aureus to β-Lactam Antibiotics by Acidic pH: ROLE OF PENICILLIN-BINDING PROTEIN PBP 2a
J. Biol. Chem. 2008 283: 12769-12776. First Published on March 12, 2008; doi:10.1074/jbc.M800079200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Fiona M. Sansom, Patrice Riedmaier, Hayley J. Newton, Michelle A. Dunstone, Christa E. Müller, Holger Stephan, Emma Byres, Travis Beddoe, Jamie Rossjohn, Peter J. Cowan, Anthony J. F. d'Apice, Simon C. Robson, and Elizabeth L. Hartland: Enzymatic Properties of an Ecto-nucleoside Triphosphate Diphosphohydrolase from Legionella pneumophila: SUBSTRATE SPECIFICITY AND REQUIREMENT FOR VIRULENCE
J. Biol. Chem. 2008 283: 12909-12918. First Published on March 12, 2008; doi:10.1074/jbc.M801006200 [Abstract] [Full Text] [PDF]

Anita Sheoran, Gyanesh Sharma, and Eric A. First: Activation of D-Tyrosine by Bacillus stearothermophilus Tyrosyl-tRNA Synthetase: 1. PRE-STEADY-STATE KINETIC ANALYSIS REVEALS THE MECHANISTIC BASIS FOR THE RECOGNITION OF D-TYROSINE
J. Biol. Chem. 2008 283: 12960-12970. First Published on March 4, 2008; doi:10.1074/jbc.M801649200 [Abstract] [Full Text] [PDF]

Anita Sheoran and Eric A. First: Activation of D-Tyrosine by Bacillus stearothermophilus Tyrosyl-tRNA Synthetase: 2. COOPERATIVE BINDING OF ATP IS LIMITED TO THE INITIAL TURNOVER OF THE ENZYME
J. Biol. Chem. 2008 283: 12971-12980. First Published on March 4, 2008; doi:10.1074/jbc.M801650200 [Abstract] [Full Text] [PDF]

Yoshifumi Itoh, Noriko Ito, Hideaki Nagase, and Motoharu Seiki: The Second Dimer Interface of MT1-MMP, the Transmembrane Domain, Is Essential for ProMMP-2 Activation on the Cell Surface
J. Biol. Chem. 2008 283: 13053-13062. First Published on March 12, 2008; doi:10.1074/jbc.M709327200 [Abstract] [Full Text] [PDF]

Ying Dang, Lai Mun Siew, and Yong-Hui Zheng: APOBEC3G Is Degraded by the Proteasomal Pathway in a Vif-dependent Manner without Being Polyubiquitylated
J. Biol. Chem. 2008 283: 13124-13131. First Published on March 6, 2008; doi:10.1074/jbc.M708728200 [Abstract] [Full Text] [PDF]

Ivan Gusarov, Marina Starodubtseva, Zhi-Qiang Wang, Lindsey McQuade, Stephen J. Lippard, Dennis J. Stuehr, and Evgeny Nudler: Bacterial Nitric-oxide Synthases Operate without a Dedicated Redox Partner
J. Biol. Chem. 2008 283: 13140-13147. First Published on March 3, 2008; doi:10.1074/jbc.M710178200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Karen L. Murphy, Xiaodong Zhang, Raul R. Gainetdinov, Jean-Martin Beaulieu, and Marc G. Caron: A Regulatory Domain in the N Terminus of Tryptophan Hydroxylase 2 Controls Enzyme Expression
J. Biol. Chem. 2008 283: 13216-13224. First Published on March 13, 2008; doi:10.1074/jbc.M706749200 [Abstract] [Full Text] [PDF]

Kasper D. Rand, Mette D. Andersen, Ole H. Olsen, Thomas J. D. Jørgensen, Henrik Østergaard, Ole N. Jensen, Henning R. Stennicke, and Egon Persson: The Origins of Enhanced Activity in Factor VIIa Analogs and the Interplay between Key Allosteric Sites Revealed by Hydrogen Exchange Mass Spectrometry
J. Biol. Chem. 2008 283: 13378-13387. First Published on March 14, 2008; doi:10.1074/jbc.M709716200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Metabolism and Bioenergetics:

Darius J. R. Lane and Alfons Lawen: Non-transferrin Iron Reduction and Uptake Are Regulated by Transmembrane Ascorbate Cycling in K562 Cells
J. Biol. Chem. 2008 283: 12701-12708. First Published on March 17, 2008; doi:10.1074/jbc.M800713200 [Abstract] [Full Text] [PDF]

Naoko Ishida, Miwa Sugiura, Fabrice Rappaport, Thanh-Lan Lai, A. William Rutherford, and Alain Boussac: Biosynthetic Exchange of Bromide for Chloride and Strontium for Calcium in the Photosystem II Oxygen-evolving Enzymes
J. Biol. Chem. 2008 283: 13330-13340. First Published on March 10, 2008; doi:10.1074/jbc.M710583200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Glycobiology and Extracellular Matrices:

Suresh Bhamidi, Michael S. Scherman, Christopher D. Rithner, Jessica E. Prenni, Delphi Chatterjee, Kay-Hooi Khoo, and Michael R. McNeil: The Identification and Location of Succinyl Residues and the Characterization of the Interior Arabinan Region Allow for a Model of the Complete Primary Structure of Mycobacterium tuberculosis Mycolyl Arabinogalactan
J. Biol. Chem. 2008 283: 12992-13000. First Published on February 26, 2008; doi:10.1074/jbc.M800222200 [Abstract] [Full Text] [PDF]

Sarah J. Goodger, Christopher J. Robinson, Kevin J. Murphy, Nijole Gasiunas, Nicholas J. Harmer, Tom L. Blundell, David A. Pye, and John T. Gallagher: Evidence That Heparin Saccharides Promote FGF2 Mitogenesis through Two Distinct Mechanisms
J. Biol. Chem. 2008 283: 13001-13008. First Published on February 14, 2008; doi:10.1074/jbc.M704531200 [Abstract] [Full Text] [PDF]

Friedrich P. Paulsen, Chee-Wai Woon, Deike Varoga, Anne Jansen, Fabian Garreis, Kristin Jäger, Marita Amm, Daniel K. Podolsky, Philipp Steven, Nicholas P. Barker, and Saadettin Sel: Intestinal Trefoil Factor/TFF3 Promotes Re-epithelialization of Corneal Wounds
J. Biol. Chem. 2008 283: 13418-13427. First Published on March 7, 2008; doi:10.1074/jbc.M800177200 [Abstract] [Full Text] [PDF]

Lipids and Lipoproteins: Metabolism, Regulation, and Signaling:

Devi Arikketh, Randy Nelson, and Jean E. Vance: Defining the Importance of Phosphatidylserine Synthase-1 (PSS1): Unexpected Viability of PSS1-Deficient Mice
J. Biol. Chem. 2008 283: 12888-12897. First Published on March 14, 2008; doi:10.1074/jbc.M800714200 [Abstract] [Full Text] [PDF]

Abdelghani El-Yassimi, Aziz Hichami, Philippe Besnard, and Naim Akhtar Khan: Linoleic Acid Induces Calcium Signaling, Src Kinase Phosphorylation, and Neurotransmitter Release in Mouse CD36-positive Gustatory Cells
J. Biol. Chem. 2008 283: 12949-12959. First Published on March 5, 2008; doi:10.1074/jbc.M707478200 [Abstract] [Full Text] [PDF]

Brendan N. Reid, Gene P. Ables, Oleg A. Otlivanchik, Gabriele Schoiswohl, Rudolf Zechner, William S. Blaner, Ira J. Goldberg, Robert F. Schwabe, Streamson C. Chua, Jr., and Li-Shin Huang: Hepatic Overexpression of Hormone-sensitive Lipase and Adipose Triglyceride Lipase Promotes Fatty Acid Oxidation, Stimulates Direct Release of Free Fatty Acids, and Ameliorates Steatosis
J. Biol. Chem. 2008 283: 13087-13099. First Published on March 12, 2008; doi:10.1074/jbc.M800533200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Membrane Transport, Structure, Function, and Biogenesis:

Mark D. Parker, Raif Musa-Aziz, Jose D. Rojas, Inyeong Choi, Christopher M. Daly, and Walter F. Boron: Characterization of Human SLC4A10 as an Electroneutral Na/HCO₃ Cotransporter (NBCn2) with Cl^– Self-exchange Activity
J. Biol. Chem. 2008 283: 12777-12788. First Published on March 4, 2008; doi:10.1074/jbc.M707829200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Paul D. W. Eckford and Frances J. Sharom: Functional Characterization of Escherichia coli MsbA: INTERACTION WITH NUCLEOTIDES AND SUBSTRATES
J. Biol. Chem. 2008 283: 12840-12850. First Published on March 15, 2008; doi:10.1074/jbc.M708274200 [Abstract] [Full Text] [PDF]

Kyle J. Moore, Christine M. Angevine, Owen D. Vincent, Brian E. Schwem, and Robert H. Fillingame: The Cytoplasmic Loops of Subunit a of Escherichia coli ATP Synthase May Participate in the Proton Translocating Mechanism
J. Biol. Chem. 2008 283: 13044-13052. First Published on March 12, 2008; doi:10.1074/jbc.M800900200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Victor A. Drover, David V. Nguyen, Claire C. Bastie, Yolanda F. Darlington, Nada A. Abumrad, Jeffrey E. Pessin, Erwin London, Daisy Sahoo, and Michael C. Phillips: CD36 Mediates Both Cellular Uptake of Very Long Chain Fatty Acids and Their Intestinal Absorption in Mice
J. Biol. Chem. 2008 283: 13108-13115. First Published on March 10, 2008; doi:10.1074/jbc.M708086200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Deming Gou, Amarjit Mishra, Tingting Weng, Lijing Su, Narendranath Reddy Chintagari, Zhixin Wang, Honghao Zhang, Li Gao, Pengcheng Wang, Heidi M. Stricker, and Lin Liu: Annexin A2 Interactions with Rab14 in Alveolar Type II Cells
J. Biol. Chem. 2008 283: 13156-13164. First Published on March 10, 2008; doi:10.1074/jbc.M801532200 [Abstract] [Full Text] [PDF]

Haotian Feng, Taksum Cheng, Nathan J. Pavlos, Kirk H. M. Yip, Amerigo Carrello, Ruth Seeber, Karin Eidne, Ming H. Zheng, and Jiake Xu: Cytoplasmic Terminus of Vacuolar Type Proton Pump Accessory Subunit Ac45 Is Required for Proper Interaction with V₀ Domain Subunits and Efficient Osteoclastic Bone Resorption
J. Biol. Chem. 2008 283: 13194-13204. First Published on January 28, 2008; doi:10.1074/jbc.M709712200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Tanja Bachhuber, Joana Almaça, Fadi Aldehni, Anil Mehta, Margarida D. Amaral, Rainer Schreiber, and Karl Kunzelmann: Regulation of the Epithelial Na⁺ Channel by the Protein Kinase CK2
J. Biol. Chem. 2008 283: 13225-13232. First Published on February 28, 2008; doi:10.1074/jbc.M704532200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Salah Abu-Hamad, Hilal Zaid, Adrian Israelson, Edna Nahon, and Varda Shoshan-Barmatz: Hexokinase-I Protection against Apoptotic Cell Death Is Mediated via Interaction with the Voltage-dependent Anion Channel-1: MAPPING THE SITE OF BINDING
J. Biol. Chem. 2008 283: 13482-13490. First Published on February 28, 2008; doi:10.1074/jbc.M708216200 [Abstract] [Full Text] [PDF]

Molecular Basis Of Cell and Developmental Biology:

Kwong Tai Cheng, Xibao Liu, Hwei Ling Ong, and Indu S. Ambudkar: Functional Requirement for Orai1 in Store-operated TRPC1-STIM1 Channels
J. Biol. Chem. 2008 283: 12935-12940. First Published on March 7, 2008; doi:10.1074/jbc.C800008200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Nanae Izumi, Katsumi Fumoto, Shunsuke Izumi, and Akira Kikuchi: GSK-3β Regulates Proper Mitotic Spindle Formation in Cooperation with a Component of the ${gamma}$ -Tubulin Ring Complex, GCP5
J. Biol. Chem. 2008 283: 12981-12991. First Published on March 3, 2008; doi:10.1074/jbc.M710282200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Sun Ok Hwang, Sarah A. Boswell, Jeong-Sun Seo, and Sam W. Lee: Novel Oxidative Stress-responsive Gene ERS25 Functions as a Regulator of the Heat-shock and Cell Death Response
J. Biol. Chem. 2008 283: 13063-13069. First Published on March 7, 2008; doi:10.1074/jbc.M709656200 [Abstract] [Full Text] [PDF]

Irina A. Potapova, Peter R. Brink, Ira S. Cohen, and Sergey V. Doronin: Culturing of Human Mesenchymal Stem Cells as Three-dimensional Aggregates Induces Functional Expression of CXCR4 That Regulates Adhesion to Endothelial Cells
J. Biol. Chem. 2008 283: 13100-13107. First Published on March 10, 2008; doi:10.1074/jbc.M800184200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Zailian Lu, Wei Liu, Huizhe Huang, Ying He, Ying Han, Yanning Rui, Yanhai Wang, Qinxi Li, Ka Ruan, Zhiyun Ye, Boon Chuan Low, Anming Meng, and Sheng-Cai Lin: Protein Encoded by the Axin^Fu Allele Effectively Down-regulates Wnt Signaling but Exerts a Dominant Negative Effect on c-Jun N-terminal Kinase Signaling
J. Biol. Chem. 2008 283: 13132-13139. First Published on March 3, 2008; doi:10.1074/jbc.M710595200 [Abstract] [Full Text] [PDF]

Junko Masuda, Ryosuke Usui, and Yoshiro Maru: Fibronectin Type I Repeat Is a Nonactivating Ligand for EphA1 and Inhibits ATF3-dependent Angiogenesis
J. Biol. Chem. 2008 283: 13148-13155. First Published on February 28, 2008; doi:10.1074/jbc.M702164200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Lisheng He, Zhibo Hou, and Robert Z. Qi: Calmodulin Binding and Cdk5 Phosphorylation of p35 Regulate Its Effect on Microtubules
J. Biol. Chem. 2008 283: 13252-13260. First Published on March 7, 2008; doi:10.1074/jbc.M706937200 [Abstract] [Full Text] [PDF]

Krishna P. Sarker, Hiromi Kataoka, Angela Chan, Stuart J. Netherton, Isabelle Pot, Mai Anh Huynh, Xiaolan Feng, Azad Bonni, Karl Riabowol, and Shirin Bonni: ING2 as a Novel Mediator of Transforming Growth Factor-β-dependent Responses in Epithelial Cells
J. Biol. Chem. 2008 283: 13269-13279. First Published on March 11, 2008; doi:10.1074/jbc.M708834200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Matthew J. Winton, Lionel M. Igaz, Margaret M. Wong, Linda K. Kwong, John Q. Trojanowski, and Virginia M.-Y. Lee: Disturbance of Nuclear and Cytoplasmic TAR DNA-binding Protein (TDP-43) Induces Disease-like Redistribution, Sequestration, and Aggregate Formation
J. Biol. Chem. 2008 283: 13302-13309. First Published on February 27, 2008; doi:10.1074/jbc.M800342200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Javier Palazuelos, Nathalie Davoust, Boris Julien, Eric Hatterer, Tania Aguado, Raphael Mechoulam, Cristina Benito, Julian Romero, Augusto Silva, Manuel Guzmán, Serge Nataf, and Ismael Galve-Roperh: The CB₂ Cannabinoid Receptor Controls Myeloid Progenitor Trafficking: INVOLVEMENT IN THE PATHOGENESIS OF AN ANIMAL MODEL OF MULTIPLE SCLEROSIS
J. Biol. Chem. 2008 283: 13320-13329. First Published on March 11, 2008; doi:10.1074/jbc.M707960200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Mariona Rabionet, Aarnoud C. van der Spoel, Chia-Chen Chuang, Benita von Tümpling-Radosta, Manja Litjens, Diane Bouwmeester, Christina C. Hellbusch, Christian Körner, Herbert Wiegandt, Karin Gorgas, Frances M. Platt, Hermann-Josef Gröne, and Roger Sandhoff: Male Germ Cells Require Polyenoic Sphingolipids with Complex Glycosylation for Completion of Meiosis: A LINK TO CERAMIDE SYNTHASE-3
J. Biol. Chem. 2008 283: 13357-13369. First Published on February 27, 2008; doi:10.1074/jbc.M800870200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Mechanisms Of Signal Transduction:

Emma C. Ferber, Mihoko Kajita, Anthony Wadlow, Lara Tobiansky, Carien Niessen, Hiroyoshi Ariga, Juliet Daniel, and Yasuyuki Fujita: A Role for the Cleaved Cytoplasmic Domain of E-cadherin in the Nucleus
J. Biol. Chem. 2008 283: 12691-12700. First Published on March 19, 2008; doi:10.1074/jbc.M708887200 [Abstract] [Full Text] [PDF] AUTHOR'S CHOICE

Jacqueline Boutilier, Claire Ceni, Promila C. Pagdala, Alison Forgie, Kenneth E. Neet, and Philip A. Barker: Proneurotrophins Require Endocytosis and Intracellular Proteolysis to Induce TrkA Activation
J. Biol. Chem. 2008 283: 12709-12716. First Published on February 25, 2008; doi:10.1074/jbc.M710018200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Yu-Ya Kao, Davide Gianni, Benjamin Bohl, Ross M. Taylor, and Gary M. Bokoch: Identification of a Conserved Rac-binding Site on NADPH Oxidases Supports a Direct GTPase Regulatory Mechanism
J. Biol. Chem. 2008 283: 12736-12746. First Published on March 17, 2008; doi:10.1074/jbc.M801010200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Momoko Hase, Takehiko Yokomizo, Takao Shimizu, and Motonao Nakamura: Characterization of an Orphan G Protein-coupled Receptor, GPR20, That Constitutively Activates G_i Proteins
J. Biol. Chem. 2008 283: 12747-12755. First Published on March 17, 2008; doi:10.1074/jbc.M709487200 [Abstract] [Full Text] [PDF]

Chiyuan Chen, Robert E. Lewis, and Michael A. White: IMP Modulates KSR1-dependent Multivalent Complex Formation to Specify ERK1/2 Pathway Activation and Response Thresholds
J. Biol. Chem. 2008 283: 12789-12796. First Published on March 10, 2008; doi:10.1074/jbc.M709305200 [Abstract] [Full Text] [PDF]

Hayet Ammar and Jean L. Closset: Clusterin Activates Survival through the Phosphatidylinositol 3-Kinase/Akt Pathway
J. Biol. Chem. 2008 283: 12851-12861. First Published on March 5, 2008; doi:10.1074/jbc.M800403200 [Abstract] [Full Text] [PDF]

Francisca C. Gushiken, Vimal Patel, Yan Liu, Subhashree Pradhan, Angela L. Bergeron, Yuandong Peng, and K. Vinod Vijayan: Protein Phosphatase 2A Negatively Regulates Integrin ${alpha}$ _IIbβ₃ Signaling
J. Biol. Chem. 2008 283: 12862-12869. First Published on March 11, 2008; doi:10.1074/jbc.M708804200 [Abstract] [Full Text] [PDF]

Rodrigo Jacamo, James Sinnett-Smith, Osvaldo Rey, Richard T. Waldron, and Enrique Rozengurt: Sequential Protein Kinase C (PKC)-dependent and PKC-independent Protein Kinase D Catalytic Activation via G_q-coupled Receptors: DIFFERENTIAL REGULATION OF ACTIVATION LOOP SER⁷⁴⁴ AND SER⁷⁴⁸ PHOSPHORYLATION
J. Biol. Chem. 2008 283: 12877-12887. First Published on March 12, 2008; doi:10.1074/jbc.M800442200 [Abstract] [Full Text] [PDF]

Dmitri V. Pechkovsky, Amelia K. Scaffidi, Tillie L. Hackett, Joanne Ballard, Furquan Shaheen, Philip J. Thompson, Victor J. Thannickal, and Darryl A. Knight: Transforming Growth Factor β1 Induces ${alpha}$ vβ3 Integrin Expression in Human Lung Fibroblasts via a β3 Integrin-, c-Src-, and p38 MAPK-dependent Pathway
J. Biol. Chem. 2008 283: 12898-12908. First Published on March 18, 2008; doi:10.1074/jbc.M708226200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Alexandra Dusa, Judith Staerk, Joanne Elliott, Christian Pecquet, Hélène A. Poirel, James A. Johnston, and Stefan N. Constantinescu: Substitution of Pseudokinase Domain Residue Val-617 by Large Non-polar Amino Acids Causes Activation of JAK2
J. Biol. Chem. 2008 283: 12941-12948. First Published on March 6, 2008; doi:10.1074/jbc.M709302200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Win D. Cheung and Gerald W. Hart: AMP-activated Protein Kinase and p38 MAPK Activate O-GlcNAcylation of Neuronal Proteins during Glucose Deprivation
J. Biol. Chem. 2008 283: 13009-13020. First Published on March 19, 2008; doi:10.1074/jbc.M801222200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Dario Barbone, Tsung-Ming Yang, Jeffrey R. Morgan, Giovanni Gaudino, and V. Courtney Broaddus: Mammalian Target of Rapamycin Contributes to the Acquired Apoptotic Resistance of Human Mesothelioma Multicellular Spheroids
J. Biol. Chem. 2008 283: 13021-13030. First Published on March 13, 2008; doi:10.1074/jbc.M709698200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Simone Barbero, Daniela Barilà, Ainhoa Mielgo, Venturina Stagni, Kiran Clair, and Dwayne Stupack: Identification of a Critical Tyrosine Residue in Caspase 8 That Promotes Cell Migration
J. Biol. Chem. 2008 283: 13031-13034. First Published on January 23, 2008; doi:10.1074/jbc.M800549200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Vasco Oliveira, William J. Romanow, Christoph Geisen, Diane M. Otterness, Frank Mercurio, Hong Gang Wang, William S. Dalton, and Robert T. Abraham: A Protective Role for the Human SMG-1 Kinase against Tumor Necrosis Factor- ${alpha}$ -induced Apoptosis
J. Biol. Chem. 2008 283: 13174-13184. First Published on March 6, 2008; doi:10.1074/jbc.M708008200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Marisa J. Wainszelbaum, Audra J. Charron, Chen Kong, Donald S. Kirkpatrick, Priya Srikanth, M. Alejandro Barbieri, Steven P. Gygi, and Philip D. Stahl: The Hominoid-specific Oncogene TBC1D3 Activates Ras and Modulates Epidermal Growth Factor Receptor Signaling and Trafficking
J. Biol. Chem. 2008 283: 13233-13242. First Published on March 4, 2008; doi:10.1074/jbc.M800234200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Stephan Huveneers, Serdar Arslan, Bob van de Water, Arnoud Sonnenberg, and Erik H. J. Danen: Integrins Uncouple Src-induced Morphological and Oncogenic Transformation
J. Biol. Chem. 2008 283: 13243-13251. First Published on March 7, 2008; doi:10.1074/jbc.M800927200 [Abstract] [Full Text] [PDF]

Adi E. Matitau and Michael P. Scheid: Phosphorylation of MEKK3 at Threonine 294 Promotes 14-3-3 Association to Inhibit Nuclear Factor ${kappa}$ B Activation
J. Biol. Chem. 2008 283: 13261-13268. First Published on February 28, 2008; doi:10.1074/jbc.M801474200 [Abstract] [Full Text] [PDF]

Jing Zheng, Wan-Hua Shen, Ting-Jia Lu, Yang Zhou, Qian Chen, Zi Wang, Ting Xiang, Yong-Chuan Zhu, Chi Zhang, Shumin Duan, and Zhi-Qi Xiong: Clathrin-dependent Endocytosis Is Required for TrkB-dependent Akt-mediated Neuronal Protection and Dendritic Growth
J. Biol. Chem. 2008 283: 13280-13288. First Published on March 19, 2008; doi:10.1074/jbc.M709930200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Meirav Zaks-Zilberman, Adrian E. Harrington, Tetsuya Ishino, and Irwin M. Chaiken: Interleukin-5 Receptor Subunit Oligomerization and Rearrangement Revealed by Fluorescence Resonance Energy Transfer Imaging
J. Biol. Chem. 2008 283: 13398-13406. First Published on March 7, 2008; doi:10.1074/jbc.M710230200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Ping Gong, Daniel J. Angelini, Shiqi Yang, Guanjun Xia, Alan S. Cross, Dean Mann, Douglas D. Bannerman, Stefanie N. Vogel, and Simeon E. Goldblum: TLR4 Signaling Is Coupled to SRC Family Kinase Activation, Tyrosine Phosphorylation of Zonula Adherens Proteins, and Opening of the Paracellular Pathway in Human Lung Microvascular Endothelia
J. Biol. Chem. 2008 283: 13437-13449. First Published on March 7, 2008; doi:10.1074/jbc.M707986200 [Abstract] [Full Text] [PDF]

Juan L. Callejas-Valera, Juan Guinea-Viniegra, Carmen Ramírez-Castillejo, Juan A. Recio, Eva Galan-Moya, Natalia Martinez, Jose M. Rojas, Santiago Ramón y Cajal, and Ricardo Sánchez-Prieto: E1a Gene Expression Blocks the ERK1/2 Signaling Pathway by Promoting Nuclear Localization and MKP Up-regulation: IMPLICATION IN v-H-Ras-INDUCED SENESCENCE
J. Biol. Chem. 2008 283: 13450-13458. First Published on March 3, 2008; doi:10.1074/jbc.M709230200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Qian Zhang, Ruolin Guo, Yan Lu, Lan Zhao, Quan Zhou, Edward M. Schwarz, Jing Huang, Di Chen, Zheng-Gen Jin, Brendan F. Boyce, and Lianping Xing: VEGF-C, a Lymphatic Growth Factor, Is a RANKL Target Gene in Osteoclasts That Enhances Osteoclastic Bone Resorption through an Autocrine Mechanism
J. Biol. Chem. 2008 283: 13491-13499. First Published on March 20, 2008; doi:10.1074/jbc.M708055200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Additions and Corrections:

Hong Zang, Adriana Irimia, Jeong-Yun Choi, Karen C. Angel, Lioudmila V. Loukachevitch, Martin Egli, and F. Peter Guengerich: Efficient and high fidelity incorporation of dCTP opposite 7,8-dihydro-8-oxodeoxyguanosine by Sulfolobus solfataricus DNA polymerase Dpo4. VOLUME 281 (2006) PAGES 2358-2372
J. Biol. Chem. 2008 283: 13500. [Full Text] [PDF]

Greg Q. Butcher, Jeff Doner, Heather Dziema, Minden Collamore, Penny W. Burgoon, and Karl Obrietan: The p42/44 mitogen-activated protein kinase pathway couples photic input to circadian clock entrainment. VOLUME 277 (2002) PAGES 29519-29525
J. Biol. Chem. 2008 283: 13500-a. [Full Text] [PDF]