JBC -- Table of Contents (Feb 22 2008, 283, (8))

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Reflections:

Kensal E. van Holde: Learning How to Be a Scientist
J. Biol. Chem. 2008 283: 4461-4463. First Published on December 19, 2007; doi:10.1074/jbc.X700002200 [Full Text] [PDF]

Accelerated Publications:

Daniel Hochbaum, Kyoungja Hong, Guillermo Barila, Fernando Ribeiro-Neto, and Daniel L. Altschuler: Epac, in Synergy with cAMP-dependent Protein Kinase (PKA), Is Required for cAMP-mediated Mitogenesis
J. Biol. Chem. 2008 283: 4464-4468. First Published on December 6, 2007; doi:10.1074/jbc.C700171200 [Abstract] [Full Text] [PDF] [Supplemental Data]

DNA: Replication, Repair, Recombination, and Chromosome Dynamics:

Caixia Guo, Tie-Shan Tang, Marzena Bienko, Ivan Dikic, and Errol C. Friedberg: Requirements for the Interaction of Mouse Pol ${kappa}$ with Ubiquitin and Its Biological Significance
J. Biol. Chem. 2008 283: 4658-4664. First Published on December 26, 2007; doi:10.1074/jbc.M709275200 [Abstract] [Full Text] [PDF]

Tadashi Nishihara, Fumikiyo Nagawa, Takeshi Imai, and Hitoshi Sakano: RAG-Heptamer Interaction in the Synaptic Complex Is a Crucial Biochemical Checkpoint for the 12/23 Recombination Rule
J. Biol. Chem. 2008 283: 4877-4885. First Published on December 18, 2007; doi:10.1074/jbc.M709890200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Jodi D. Richards, Kenneth A. Johnson, Huanting Liu, Anne-Marie McRobbie, Stephen McMahon, Muse Oke, Lester Carter, James H. Naismith, and Malcolm F. White: Structure of the DNA Repair Helicase Hel308 Reveals DNA Binding and Autoinhibitory Domains
J. Biol. Chem. 2008 283: 5118-5126. First Published on December 4, 2007; doi:10.1074/jbc.M707548200 [Abstract] [Full Text] [PDF]

Transcription, Chromatin, and Epigenetics:

Aline Gréchez-Cassiau, Béatrice Rayet, Fabienne Guillaumond, Michèle Teboul, and Franck Delaunay: The Circadian Clock Component BMAL1 Is a Critical Regulator of p21^WAF1/CIP1 Expression and Hepatocyte Proliferation
J. Biol. Chem. 2008 283: 4535-4542. First Published on December 17, 2007; doi:10.1074/jbc.M705576200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Pratibha B. Hebbar and Trevor K. Archer: Altered Histone H1 Stoichiometry and an Absence of Nucleosome Positioning on Transfected DNA
J. Biol. Chem. 2008 283: 4595-4601. First Published on December 22, 2007; doi:10.1074/jbc.M709121200 [Abstract] [Full Text] [PDF]

Benoît Porée, Magdalini Kypriotou, Christos Chadjichristos, Gallic Beauchef, Emmanuelle Renard, Florence Legendre, Martine Melin, Sylviane Gueret, Daniel-Jean Hartmann, Frédéric Malléin-Gerin, Jean-Pierre Pujol, Karim Boumediene, and Philippe Galéra: Interleukin-6 (IL-6) and/or Soluble IL-6 Receptor Down-regulation of Human Type II Collagen Gene Expression in Articular Chondrocytes Requires a Decrease of Sp1·Sp3 Ratio and of the Binding Activity of Both Factors to the COL2A1 Promoter
J. Biol. Chem. 2008 283: 4850-4865. First Published on December 7, 2007; doi:10.1074/jbc.M706387200 [Abstract] [Full Text] [PDF]

Andrew P. VanDemark, Hua Xin, Laura McCullough, Robert Rawlins, Shayla Bentley, Annie Heroux, David J. Stillman, Christopher P. Hill, and Tim Formosa: Structural and Functional Analysis of the Spt16p N-terminal Domain Reveals Overlapping Roles of yFACT Subunits
J. Biol. Chem. 2008 283: 5058-5068. First Published on December 18, 2007; doi:10.1074/jbc.M708682200 [Abstract] [Full Text] [PDF] [Supplemental Data]

RNA: Processing and Catalysis:

Jade Bernstein, Dimeka N. Patterson, Gerald M. Wilson, and Eric A. Toth: Characterization of the Essential Activities of Saccharomyces cerevisiae Mtr4p, a 3' $->$ 5' Helicase Partner of the Nuclear Exosome
J. Biol. Chem. 2008 283: 4930-4942. First Published on December 20, 2007; doi:10.1074/jbc.M706677200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Protein Synthesis, Post-Translational Modification, and Degradation:

Ziv Porat, Guy Landau, Zippi Bercovich, Dasha Krutauz, Michael Glickman, and Chaim Kahana: Yeast Antizyme Mediates Degradation of Yeast Ornithine Decarboxylase by Yeast but Not by Mammalian Proteasome: NEW INSIGHTS ON YEAST ANTIZYME
J. Biol. Chem. 2008 283: 4528-4534. First Published on December 18, 2007; doi:10.1074/jbc.M708088200 [Abstract] [Full Text] [PDF]

Mimi C. Sammarco, Scott Ditch, Ayan Banerjee, and Ed Grabczyk: Ferritin L and H Subunits Are Differentially Regulated on a Post-transcriptional Level
J. Biol. Chem. 2008 283: 4578-4587. First Published on December 26, 2007; doi:10.1074/jbc.M703456200 [Abstract] [Full Text] [PDF]

Dong Wook Choi, Yu-Mi Seo, Eun-A Kim, Ki Sa Sung, Jang Won Ahn, Sang-Joon Park, Seung-Rock Lee, and Cheol Yong Choi: Ubiquitination and Degradation of Homeodomain-interacting Protein Kinase 2 by WD40 Repeat/SOCS Box Protein WSB-1
J. Biol. Chem. 2008 283: 4682-4689. First Published on December 19, 2007; doi:10.1074/jbc.M708873200 [Abstract] [Full Text] [PDF]

Alexandros D. Petropoulos, Ekaterini C. Kouvela, George P. Dinos, and Dimitrios L. Kalpaxis: Stepwise Binding of Tylosin and Erythromycin to Escherichia coli Ribosomes, Characterized by Kinetic and Footprinting Analysis
J. Biol. Chem. 2008 283: 4756-4765. First Published on December 13, 2007; doi:10.1074/jbc.M708371200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Bin Guan, Pooja Pungaliya, Xiang Li, Carlos Uquillas, Laura N. Mutton, Eric H. Rubin, and Charles J. Bieberich: Ubiquitination by TOPORS Regulates the Prostate Tumor Suppressor NKX3.1
J. Biol. Chem. 2008 283: 4834-4840. First Published on December 12, 2007; doi:10.1074/jbc.M708630200 [Abstract] [Full Text] [PDF]

Kenji Kizawa, Hidenari Takahara, Heinz Troxler, Peter Kleinert, Urara Mochida, and Claus W. Heizmann: Specific Citrullination Causes Assembly of a Globular S100A3 Homotetramer: A PUTATIVE Ca²⁺ MODULATOR MATURES HUMAN HAIR CUTICLE
J. Biol. Chem. 2008 283: 5004-5013. First Published on December 14, 2007; doi:10.1074/jbc.M709357200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Brad J. Niles, Michael S. Clegg, Lynn A. Hanna, Susan S. Chou, Tony Y. Momma, Heeok Hong, and Carl L. Keen: Zinc Deficiency-induced Iron Accumulation, a Consequence of Alterations in Iron Regulatory Protein-binding Activity, Iron Transporters, and Iron Storage Proteins
J. Biol. Chem. 2008 283: 5168-5177. First Published on December 11, 2007; doi:10.1074/jbc.M709043200 [Abstract] [Full Text] [PDF]

Protein Structure and Folding:

Rei Nomura, Yoshikazu Suzuki, Akira Kakizuka, and Hisato Jingami: Direct Detection of the Interaction between Recombinant Soluble Extracellular Regions in the Heterodimeric Metabotropic ${gamma}$ -Aminobutyric Acid Receptor
J. Biol. Chem. 2008 283: 4665-4673. First Published on December 28, 2007; doi:10.1074/jbc.M705202200 [Abstract] [Full Text] [PDF] [Supplemental Data]

María E. Primo, Sebastián Klinke, Mauricio P. Sica, Fernando A. Goldbaum, Jean Jakoncic, Edgardo Poskus, and Mario R. Ermácora: Structure of the Mature Ectodomain of the Human Receptor-type Protein-tyrosine Phosphatase IA-2
J. Biol. Chem. 2008 283: 4674-4681. First Published on November 29, 2007; doi:10.1074/jbc.M708144200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Elena Makareeva, Edward L. Mertz, Natalia V. Kuznetsova, Mary B. Sutter, Angela M. DeRidder, Wayne A. Cabral, Aileen M. Barnes, Daniel J. McBride, Joan C. Marini, and Sergey Leikin: Structural Heterogeneity of Type I Collagen Triple Helix and Its Role in Osteogenesis Imperfecta
J. Biol. Chem. 2008 283: 4787-4798. First Published on December 11, 2007; doi:10.1074/jbc.M705773200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Annalisa Relini, Silvia De Stefano, Silvia Torrassa, Ornella Cavalleri, Ranieri Rolandi, Alessandra Gliozzi, Sofia Giorgetti, Sara Raimondi, Loredana Marchese, Laura Verga, Antonio Rossi, Monica Stoppini, and Vittorio Bellotti: Heparin Strongly Enhances the Formation of β₂-Microglobulin Amyloid Fibrils in the Presence of Type I Collagen
J. Biol. Chem. 2008 283: 4912-4920. First Published on December 3, 2007; doi:10.1074/jbc.M702712200 [Abstract] [Full Text] [PDF]

Hugues Ouellet, Larissa M. Podust, and Paul R. Ortiz de Montellano: Mycobacterium tuberculosis CYP130: CRYSTAL STRUCTURE, BIOPHYSICAL CHARACTERIZATION, AND INTERACTIONS WITH ANTIFUNGAL AZOLE DRUGS
J. Biol. Chem. 2008 283: 5069-5080. First Published on December 18, 2007; doi:10.1074/jbc.M708734200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Roland Gamsjaeger, Michael K. Swanton, Felix J. Kobus, Eija Lehtomaki, Jason A. Lowry, Ann H. Kwan, Jacqueline M. Matthews, and Joel P. Mackay: Structural and Biophysical Analysis of the DNA Binding Properties of Myelin Transcription Factor 1
J. Biol. Chem. 2008 283: 5158-5167. First Published on December 11, 2007; doi:10.1074/jbc.M703772200 [Abstract] [Full Text] [PDF]

Takayuki Ohnuma, Shoko Onaga, Katsuyoshi Murata, Toki Taira, and Etsuko Katoh: LysM Domains from Pteris ryukyuensis Chitinase-A: A STABILITY STUDY AND CHARACTERIZATION OF THE CHITIN-BINDING SITE
J. Biol. Chem. 2008 283: 5178-5187. First Published on December 14, 2007; doi:10.1074/jbc.M707156200 [Abstract] [Full Text] [PDF]

Enzyme Catalysis and Regulation:

Georgios Tsiavaliaris, Setsuko Fujita-Becker, Ulrike Dürrwang, Ralph P. Diensthuber, Michael A. Geeves, and Dietmar J. Manstein: Mechanism, Regulation, and Functional Properties of Dictyostelium Myosin-1B
J. Biol. Chem. 2008 283: 4520-4527. First Published on December 17, 2007; doi:10.1074/jbc.M708113200 [Abstract] [Full Text] [PDF]

Shaileja Chopra, Russell M. Dooling, Caroline Glyn Horner, and Elizabeth E. Howell: A Balancing Act between Net Uptake of Water during Dihydrofolate Binding and Net Release of Water upon NADPH Binding in R67 Dihydrofolate Reductase
J. Biol. Chem. 2008 283: 4690-4698. First Published on December 17, 2007; doi:10.1074/jbc.M709443200 [Abstract] [Full Text] [PDF] [Supplemental Data]

James M. Pauff, Jinjin Zhang, Charles E. Bell, and Russ Hille: Substrate Orientation in Xanthine Oxidase: CRYSTAL STRUCTURE OF ENZYME IN REACTION WITH 2-HYDROXY-6-METHYLPURINE
J. Biol. Chem. 2008 283: 4818-4824. First Published on December 6, 2007; doi:10.1074/jbc.M707918200 [Abstract] [Full Text] [PDF]

Emmanuele Severi, Axel Müller, Jennifer R. Potts, Andrew Leech, David Williamson, Keith S. Wilson, and Gavin H. Thomas: Sialic Acid Mutarotation Is Catalyzed by the Escherichia coli β-Propeller Protein YjhT
J. Biol. Chem. 2008 283: 4841-4849. First Published on December 5, 2007; doi:10.1074/jbc.M707822200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Viviana Job, Raphaël Carapito, Thierry Vernet, Andréa Dessen, and André Zapun: Common Alterations in PBP1a from Resistant Streptococcus pneumoniae Decrease Its Reactivity toward β-Lactams: STRUCTURAL INSIGHTS
J. Biol. Chem. 2008 283: 4886-4894. First Published on November 30, 2007; doi:10.1074/jbc.M706181200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Yuxiang Zheng, William E. Boeglin, Claus Schneider, and Alan R. Brash: A 49-kDa Mini-lipoxygenase from Anabaena sp. PCC 7120 Retains Catalytically Complete Functionality
J. Biol. Chem. 2008 283: 5138-5147. First Published on December 10, 2007; doi:10.1074/jbc.M705780200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Metabolism and Bioenergetics:

Chi Chen, Kristopher W. Krausz, Jeffrey R. Idle, and Frank J. Gonzalez: Identification of Novel Toxicity-associated Metabolites by Metabolomics and Mass Isotopomer Analysis of Acetaminophen Metabolism in Wild-type and Cyp2e1-null Mice
J. Biol. Chem. 2008 283: 4543-4559. First Published on December 19, 2007; doi:10.1074/jbc.M706299200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Hiroaki Taguchi, Stephanie Planque, Yasuhiro Nishiyama, Jindrich Symersky, Stephane Boivin, Paul Szabo, Robert P. Friedland, Paul A. Ramsland, Allen B. Edmundson, Marc E. Weksler, and Sudhir Paul: Autoantibody-catalyzed Hydrolysis of Amyloid β Peptide
J. Biol. Chem. 2008 283: 4714-4722. First Published on December 17, 2007; doi:10.1074/jbc.M707983200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Yusuke Seino, Takashi Miki, Hiroshi Kiyonari, Takaya Abe, Wakako Fujimoto, Keita Kimura, Ayako Takeuchi, Yoshihisa Takahashi, Yutaka Oiso, Toshihiko Iwanaga, and Susumu Seino: Isx Participates in the Maintenance of Vitamin A Metabolism by Regulation of β-Carotene 15,15'-Monooxygenase (Bcmo1) Expression
J. Biol. Chem. 2008 283: 4905-4911. First Published on December 19, 2007; doi:10.1074/jbc.M707928200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Glycobiology and Extracellular Matrices:

Midori Umekawa, Wei Huang, Bing Li, Kiyotaka Fujita, Hisashi Ashida, Lai-Xi Wang, and Kenji Yamamoto: Mutants of Mucor hiemalis Endo-β-N-acetylglucosaminidase Show Enhanced Transglycosylation and Glycosynthase-like Activities
J. Biol. Chem. 2008 283: 4469-4479. First Published on December 20, 2007; doi:10.1074/jbc.M707137200 [Abstract] [Full Text] [PDF]

María Fabiana De Rosa, Cameron Ackerley, Bernice Wang, Shinya Ito, David M. Clarke, and Clifford Lingwood: Inhibition of Multidrug Resistance by AdamantylGb₃, a Globotriaosylceramide Analog
J. Biol. Chem. 2008 283: 4501-4511. First Published on November 13, 2007; doi:10.1074/jbc.M705473200 [Abstract] [Full Text] [PDF]

Izabella Z. A. Pawluczyk, Samita R. Patel, and Kevin P. G. Harris: Perindoprilat Modulates the Activity of Lipoprotein Receptor-related Protein in Human Mesangial Cells
J. Biol. Chem. 2008 283: 4588-4594. First Published on December 22, 2007; doi:10.1074/jbc.M709001200 [Abstract] [Full Text] [PDF]

Lipids and Lipoproteins:

Abdel M. Hebbachi, Brian L. Knight, David Wiggins, Dilip D. Patel, and Geoffrey F. Gibbons: Peroxisome Proliferator-activated Receptor ${alpha}$ Deficiency Abolishes the Response of Lipogenic Gene Expression to Re-feeding: RESTORATION OF THE NORMAL RESPONSE BY ACTIVATION OF LIVER X RECEPTOR ${alpha}$
J. Biol. Chem. 2008 283: 4866-4876. First Published on December 13, 2007; doi:10.1074/jbc.M709471200 [Abstract] [Full Text] [PDF]

Mohammed Saleem, Michaela C. Meyer, Daniel Breitenstein, and Hans-Joachim Galla: The Surfactant Peptide KL₄ in Lipid Monolayers: PHASE BEHAVIOR, TOPOGRAPHY, AND CHEMICAL DISTRIBUTION
J. Biol. Chem. 2008 283: 5195-5207. First Published on December 19, 2007; doi:10.1074/jbc.M705944200 [Abstract] [Full Text] [PDF]

Membrane Transport, Structure, Function, and Biogenesis:

Kevin C. Jefferies and Michael Forgac: Subunit H of the Vacuolar (H⁺) ATPase Inhibits ATP Hydrolysis by the Free V₁ Domain by Interaction with the Rotary Subunit F
J. Biol. Chem. 2008 283: 4512-4519. First Published on December 21, 2007; doi:10.1074/jbc.M707144200 [Abstract] [Full Text] [PDF]

Nicolas Picard, Dominique Eladari, Soumaya El Moghrabi, Carole Planès, Soline Bourgeois, Pascal Houillier, Qing Wang, Michel Burnier, Georges Deschenes, Mark A. Knepper, Pierre Meneton, and Régine Chambrey: Defective ENaC Processing and Function in Tissue Kallikrein-deficient Mice
J. Biol. Chem. 2008 283: 4602-4611. First Published on December 17, 2007; doi:10.1074/jbc.M705664200 [Abstract] [Full Text] [PDF]

Lindsay D. Nelson, Arthur E. Johnson, and Erwin London: How Interaction of Perfringolysin O with Membranes Is Controlled by Sterol Structure, Lipid Structure, and Physiological Low pH: INSIGHTS INTO THE ORIGIN OF PERFRINGOLYSIN O-LIPID RAFT INTERACTION
J. Biol. Chem. 2008 283: 4632-4642. First Published on December 17, 2007; doi:10.1074/jbc.M709483200 [Abstract] [Full Text] [PDF]

Abderrahmane Alioua, Rong Lu, Yogesh Kumar, Mansoureh Eghbali, Pallob Kundu, Ligia Toro, and Enrico Stefani: Slo1 Caveolin-binding Motif, a Mechanism of Caveolin-1-Slo1 Interaction Regulating Slo1 Surface Expression
J. Biol. Chem. 2008 283: 4808-4817. First Published on December 12, 2007; doi:10.1074/jbc.M709802200 [Abstract] [Full Text] [PDF]

Victoria Balannik, Robert A. Lamb, and Lawrence H. Pinto: The Oligomeric State of the Active BM2 Ion Channel Protein of Influenza B Virus
J. Biol. Chem. 2008 283: 4895-4904. First Published on December 11, 2007; doi:10.1074/jbc.M709433200 [Abstract] [Full Text] [PDF]

Daniel Hilger, Maret Böhm, Alexandra Hackmann, and Heinrich Jung: Role of Ser-340 and Thr-341 in Transmembrane Domain IX of the Na⁺/Proline Transporter PutP of Escherichia coli in Ligand Binding and Transport
J. Biol. Chem. 2008 283: 4921-4929. First Published on December 21, 2007; doi:10.1074/jbc.M706741200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Edward J. Beck, Yu Yang, Sirin Yaemsiri, and Viswanathan Raghuram: Conformational Changes in a Pore-lining Helix Coupled to Cystic Fibrosis Transmembrane Conductance Regulator Channel Gating
J. Biol. Chem. 2008 283: 4957-4966. First Published on December 3, 2007; doi:10.1074/jbc.M702235200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Liliana Mora, Mirjam Klepsch, Richard H. Buckingham, Valérie Heurgué-Hamard, Stephanie Kervestin, and Miklos de Zamaroczy: Dual Roles of the Central Domain of Colicin D tRNase in TonB-mediated Import and in Immunity
J. Biol. Chem. 2008 283: 4993-5003. First Published on December 14, 2007; doi:10.1074/jbc.M706846200 [Abstract] [Full Text] [PDF]

Lene E. Olesen, Marijn G. J. Ford, Eva M. Schmid, Yvonne Vallis, M. Madan Babu, Peter H. Li, Ian G. Mills, Harvey T. McMahon, and Gerrit J. K. Praefcke: Solitary and Repetitive Binding Motifs for the AP2 Complex ${alpha}$ -Appendage in Amphiphysin and Other Accessory Proteins
J. Biol. Chem. 2008 283: 5099-5109. First Published on November 6, 2007; doi:10.1074/jbc.M708621200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Damien S. K. Samways, Keisuke Migita, Zhiyuan Li, and Terrance M. Egan: On the Role of the First Transmembrane Domain in Cation Permeability and Flux of the ATP-gated P2X₂ Receptor
J. Biol. Chem. 2008 283: 5110-5117. First Published on November 29, 2007; doi:10.1074/jbc.M708713200 [Abstract] [Full Text] [PDF]

David C. Oliver and Mark Paetzel: Crystal Structure of the Major Periplasmic Domain of the Bacterial Membrane Protein Assembly Facilitator YidC
J. Biol. Chem. 2008 283: 5208-5216. First Published on December 19, 2007; doi:10.1074/jbc.M708936200 [Abstract] [Full Text] [PDF]

Molecular Basis Of Cell and Developmental Biology:

Weixi Zhang, Nianlan Yang, and Xing-Ming Shi: Regulation of Mesenchymal Stem Cell Osteogenic Differentiation by Glucocorticoid-induced Leucine Zipper (GILZ)
J. Biol. Chem. 2008 283: 4723-4729. First Published on December 14, 2007; doi:10.1074/jbc.M704147200 [Abstract] [Full Text] [PDF]

Lorenzo Querin, Rossella Sanvito, Fulvio Magni, Stefano Busti, Alain Van Dorsselaer, Lilia Alberghina, and Marco Vanoni: Proteomic Analysis of a Nutritional Shift-up in Saccharomyces cerevisiae Identifies Gvp36 as a BAR-containing Protein Involved in Vesicular Traffic and Nutritional Adaptation
J. Biol. Chem. 2008 283: 4730-4743. First Published on December 21, 2007; doi:10.1074/jbc.M707787200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Yongjun Wang, Rajat Singh, Ashish C. Massey, Saul S. Kane, Susmita Kaushik, Taneisha Grant, Youqing Xiang, Ana Maria Cuervo, and Mark J. Czaja: Loss of Macroautophagy Promotes or Prevents Fibroblast Apoptosis Depending on the Death Stimulus
J. Biol. Chem. 2008 283: 4766-4777. First Published on December 11, 2007; doi:10.1074/jbc.M706666200 [Abstract] [Full Text] [PDF] [Supplemental Data] [Summary]

Jérôme E. Lafont, Sonia Talma, Christine Hopfgarten, and Christopher L. Murphy: Hypoxia Promotes the Differentiated Human Articular Chondrocyte Phenotype through SOX9-dependent and -independent Pathways
J. Biol. Chem. 2008 283: 4778-4786. First Published on December 12, 2007; doi:10.1074/jbc.M707729200 [Abstract] [Full Text] [PDF]

Takashi Nakamura, Susana de Vega, Satoshi Fukumoto, Lucia Jimenez, Fernando Unda, and Yoshihiko Yamada: Transcription Factor Epiprofin Is Essential for Tooth Morphogenesis by Regulating Epithelial Cell Fate and Tooth Number
J. Biol. Chem. 2008 283: 4825-4833. First Published on December 21, 2007; doi:10.1074/jbc.M708388200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Nathalie Campo, Kathleen A. Marquis, and David Z. Rudner: SpoIIQ Anchors Membrane Proteins on Both Sides of the Sporulation Septum in Bacillus subtilis
J. Biol. Chem. 2008 283: 4975-4982. First Published on December 11, 2007; doi:10.1074/jbc.M708024200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Noriko Kaji, Aya Muramoto, and Kensaku Mizuno: LIM Kinase-mediated Cofilin Phosphorylation during Mitosis Is Required for Precise Spindle Positioning
J. Biol. Chem. 2008 283: 4983-4992. First Published on December 12, 2007; doi:10.1074/jbc.M708644200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Tomas D. Perez, Masako Tamada, Michael P. Sheetz, and W. James Nelson: Immediate-Early Signaling Induced by E-cadherin Engagement and Adhesion
J. Biol. Chem. 2008 283: 5014-5022. First Published on December 17, 2007; doi:10.1074/jbc.M705209200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Charles N. Birts, C. Howard Barton, and David C. Wilton: A Catalytically Independent Physiological Function for Human Acute Phase Protein Group IIA Phospholipase A₂: CELLULAR UPTAKE FACILITATES CELL DEBRIS REMOVAL
J. Biol. Chem. 2008 283: 5034-5045. First Published on December 17, 2007; doi:10.1074/jbc.M708844200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Benjamin L. Prosser, Nathan T. Wright, Erick O. Hernãndez-Ochoa, Kristen M. Varney, Yewei Liu, Rotimi O. Olojo, Danna B. Zimmer, David J. Weber, and Martin F. Schneider: S100A1 Binds to the Calmodulin-binding Site of Ryanodine Receptor and Modulates Skeletal Muscle Excitation-Contraction Coupling
J. Biol. Chem. 2008 283: 5046-5057. First Published on December 17, 2007; doi:10.1074/jbc.M709231200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Mechanisms Of Signal Transduction:

Zhe Wang, Tianhua Ma, Xiaoke Chi, and Duanqing Pei: Aromatic Residues in the C-terminal Domain 2 Are Required for Nanog to Mediate LIF-independent Self-renewal of Mouse Embryonic Stem Cells
J. Biol. Chem. 2008 283: 4480-4489. First Published on December 17, 2007; doi:10.1074/jbc.M706009200 [Abstract] [Full Text] [PDF]

Jonathan A. Kelber, Gidi Shani, Evan C. Booker, Wylie W. Vale, and Peter C. Gray: Cripto Is a Noncompetitive Activin Antagonist That Forms Analogous Signaling Complexes with Activin and Nodal
J. Biol. Chem. 2008 283: 4490-4500. First Published on December 18, 2007; doi:10.1074/jbc.M704960200 [Abstract] [Full Text] [PDF]

Michelle E. Kimple, Jamie W. Joseph, Candice L. Bailey, Patrick T. Fueger, Ian A. Hendry, Christopher B. Newgard, and Patrick J. Casey: G ${alpha}$ _z Negatively Regulates Insulin Secretion and Glucose Clearance
J. Biol. Chem. 2008 283: 4560-4567. First Published on December 20, 2007; doi:10.1074/jbc.M706481200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Paul S. Donnelly, Aphrodite Caragounis, Tai Du, Katrina M. Laughton, Irene Volitakis, Robert A. Cherny, Robyn A. Sharples, Andrew F. Hill, Qiao-Xin Li, Colin L. Masters, Kevin J. Barnham, and Anthony R. White: Selective Intracellular Release of Copper and Zinc Ions from Bis(thiosemicarbazonato) Complexes Reduces Levels of Alzheimer Disease Amyloid-β Peptide
J. Biol. Chem. 2008 283: 4568-4577. First Published on December 17, 2007; doi:10.1074/jbc.M705957200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Judith Kraut-Cohen, William J. Muller, and Ari Elson: Protein-tyrosine Phosphatase ${epsilon}$ Regulates Shc Signaling in a Kinase-specific Manner: INCREASING COHERENCE IN TYROSINE PHOSPHATASE SIGNALING
J. Biol. Chem. 2008 283: 4612-4621. First Published on December 19, 2007; doi:10.1074/jbc.M708822200 [Abstract] [Full Text] [PDF]

Wei-Chiao Chang, Joseph Di Capite, Karthika Singaravelu, Charmaine Nelson, Victoria Halse, and Anant B. Parekh: Local Ca²⁺ Influx through Ca²⁺ Release-activated Ca²⁺ (CRAC) Channels Stimulates Production of an Intracellular Messenger and an Intercellular Pro-inflammatory Signal
J. Biol. Chem. 2008 283: 4622-4631. First Published on December 21, 2007; doi:10.1074/jbc.M705002200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Akihide Tanimoto, Yoshitaka Murata, Ke-Yong Wang, Masato Tsutsui, Kimitoshi Kohno, and Yasuyuki Sasaguri: Monocyte Chemoattractant Protein-1 Expression Is Enhanced by Granulocyte-Macrophage Colony-stimulating Factor via Jak2-Stat5 Signaling and Inhibited by Atorvastatin in Human Monocytic U937 Cells
J. Biol. Chem. 2008 283: 4643-4651. First Published on December 18, 2007; doi:10.1074/jbc.M708853200 [Abstract] [Full Text] [PDF]

Sumin Kang, Shaozhong Dong, Ailan Guo, Hong Ruan, Sagar Lonial, Hanna Jean Khoury, Ting-Lei Gu, and Jing Chen: Epidermal Growth Factor Stimulates RSK2 Activation through Activation of the MEK/ERK Pathway and Src-dependent Tyrosine Phosphorylation of RSK2 at Tyr-529
J. Biol. Chem. 2008 283: 4652-4657. First Published on December 21, 2007; doi:10.1074/jbc.M709673200 [Abstract] [Full Text] [PDF]

Jeremy A. Ross, Zsuzsanna S. Nagy, and Robert A. Kirken: The PHB1/2 Phosphocomplex Is Required for Mitochondrial Homeostasis and Survival of Human T Cells
J. Biol. Chem. 2008 283: 4699-4713. First Published on December 17, 2007; doi:10.1074/jbc.M708232200 [Abstract] [Full Text] [PDF]

Shahid Noor, Howard Goldfine, Dawn E. Tucker, Saritha Suram, Laurel L. Lenz, Shizuo Akira, Satoshi Uematsu, Milena Girotti, Joseph V. Bonventre, Kevin Breuel, David L. Williams, and Christina C. Leslie: Activation of Cytosolic Phospholipase A₂ ${alpha}$ in Resident Peritoneal Macrophages by Listeria monocytogenes Involves Listeriolysin O and TLR2
J. Biol. Chem. 2008 283: 4744-4755. First Published on December 14, 2007; doi:10.1074/jbc.M709956200 [Abstract] [Full Text] [PDF]

Tristan J. Iseli, Jonathan S. Oakhill, Michael F. Bailey, Sheena Wee, Mark Walter, Bryce J. van Denderen, Laura A. Castelli, Frosa Katsis, Lee A. Witters, David Stapleton, S. Lance Macaulay, Belinda J. Michell, and Bruce E. Kemp: AMP-activated Protein Kinase Subunit Interactions: β1: ${gamma}$ 1 ASSOCIATION REQUIRES β1 Thr-263 AND Tyr-267
J. Biol. Chem. 2008 283: 4799-4807. First Published on December 13, 2007; doi:10.1074/jbc.M708298200 [Abstract] [Full Text] [PDF]

Michael Macoritto, Loan Nguyen-Yamamoto, Dao Chao Huang, Sara Samuel, Xian Fang Yang, Tian Tian Wang, John H. White, and Richard Kremer: Phosphorylation of the Human Retinoid X Receptor ${alpha}$ at Serine 260 Impairs Coactivator(s) Recruitment and Induces Hormone Resistance to Multiple Ligands
J. Biol. Chem. 2008 283: 4943-4956. First Published on November 14, 2007; doi:10.1074/jbc.M707517200 [Abstract] [Full Text] [PDF]

Bernhard Knierim, Klaus Peter Hofmann, Wolfgang Gärtner, Wayne L. Hubbell, and Oliver P. Ernst: Rhodopsin and 9-Demethyl-retinal Analog: EFFECT OF A PARTIAL AGONIST ON DISPLACEMENT OF TRANSMEMBRANE HELIX 6 IN CLASS A G PROTEIN-COUPLED RECEPTORS
J. Biol. Chem. 2008 283: 4967-4974. First Published on December 6, 2007; doi:10.1074/jbc.M703059200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Fong-Pin Liang, Chao-Hsiung Lin, Cheng-Deng Kuo, Hsueh-Ping Chao, and Shu-Ling Fu: Suppression of v-Src Transformation by Andrographolide via Degradation of the v-Src Protein and Attenuation of the Erk Signaling Pathway
J. Biol. Chem. 2008 283: 5023-5033. First Published on December 17, 2007; doi:10.1074/jbc.M705877200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Lan V. Pham, Hai-Jun Zhou, Yen-Chiu Lin-Lee, Archito T. Tamayo, Linda C. Yoshimura, Lingchen Fu, Bryant G. Darnay, and Richard J. Ford: Nuclear Tumor Necrosis Factor Receptor-associated Factor 6 in Lymphoid Cells Negatively Regulates c-Myb-mediated Transactivation through Small Ubiquitin-related Modifier-1 Modification
J. Biol. Chem. 2008 283: 5081-5089. First Published on December 19, 2007; doi:10.1074/jbc.M706307200 [Abstract] [Full Text] [PDF] [Supplemental Data]

Chunbo Yuan, Robert J. O'Connell, Andrew Wilson, Andrzej Z. Pietrzykowski, and Steven N. Treistman: Acute Alcohol Tolerance Is Intrinsic to the BK_Ca Protein, but Is Modulated by the Lipid Environment
J. Biol. Chem. 2008 283: 5090-5098. First Published on December 15, 2007; doi:10.1074/jbc.M708214200 [Abstract] [Full Text] [PDF]

Yi Shen, Dianne S. Hirsch, Christy A. Sasiela, and Wen Jin Wu: Cdc42 Regulates E-cadherin Ubiquitination and Degradation through an Epidermal Growth Factor Receptor to Src-mediated Pathway
J. Biol. Chem. 2008 283: 5127-5137. First Published on December 5, 2007; doi:10.1074/jbc.M703300200 [Abstract] [Full Text] [PDF]

Biomolecular Networks:

Laura R. Jarboe, Daniel R. Hyduke, Linh M. Tran, Katherine J. Y. Chou, and James C. Liao: Determination of the Escherichia coli S-Nitrosoglutathione Response Network Using Integrated Biochemical and Systems Analysis
J. Biol. Chem. 2008 283: 5148-5157. First Published on December 10, 2007; doi:10.1074/jbc.M706018200 [Abstract] [Full Text] [PDF]

Jagadish C. Ghosh, Takehiko Dohi, Byoung Heon Kang, and Dario C. Altieri: Hsp60 Regulation of Tumor Cell Apoptosis
J. Biol. Chem. 2008 283: 5188-5194. First Published on December 17, 2007; doi:10.1074/jbc.M705904200 [Abstract] [Full Text] [PDF]