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On The Cover: Top, mitochondria (green) are degraded by lysosomes (red) by the process of macroautophagy (right portion of diagram). Bottom, selective cytosolic proteins are targeted to the lysosomal receptor LAMP-2A (green) via the chaperone Hsc70 (red) in chaperone-mediated autophagy (left diagram). For details see the article by Wang et al., pages 4766–4777.

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