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The Journal of Biological Chemistry is owned and published by the American Society of Biochemistry and Molecular Biology, Inc. It is published weekly in printed and electronic versions. Information about the JOURNAL is available on-line at: http://www.jbc.org. Its editorial policies are the responsibility of the Editor-in-Chief, the Associate Editors, and the Editorial Board under the general authority of the Publications Committee and the Council of ASBMB.
The JOURNAL publishes papers based on original research that are judged, after editorial review, to make a novel and important contribution to the understanding of any area of biochemistry or molecular biology. Manuscripts may be submitted for consideration as Regular Papers or Accelerated Publications. The JOURNAL also publishes Minireviews, all of which are by invitation only. Authors are urged to keep the length of Regular Papers to six printed pages or less. Accelerated Publications can be no longer than five printed pages.
For detailed submission instructions see http://www.jbc.org/misc/ifora.shtml
Accelerated Publications are intended to present new information of exceptional novelty, importance and interest to the broad readership of the JOURNAL. Accelerated Publications must be five printed pages or less, including all figures, references and tables. They are not intended simply to be short versions of Regular Papers. Because the criteria for acceptance of Accelerated Publications are considerably more stringent and the review process is expedited, an Associate Editor may judge a manuscript unsuitable without obtaining a full review.
After acceptance, the manuscript is placed on-line within 24 hours as a JBC Paper in Press. Please note that structural coordinates relevant to papers describing experimentally determined new structure determinations must be submitted to the Protein Data Bank and released upon acceptance since publication will occur within 24 hours of manuscript acceptance. No data is to be withdrawn from PDB once a paper has been accepted and published as a Papers in Press (PIP) article.
As of 12/06, PDB no longer accepts coordinates for model structures determined by computational methods. The coordinates must be included as a supplement to the online paper and formatted just as if it were a PDB submission.
We do not have an embargo policy since the papers that are accepted and are in JBC Papers in Press are considered to be formally published on the date of appearance in JBC Papers in Press.
For NIH funded articles, the final redacted versions of all research articles resulting from partially or complete support from NIH will be deposited immediately in PubMed Central by ASBMB and will be subject to a 12 month embargo period.
Publication Charges
Page Charges -- $75 per journal page
Color Figures -- We encourage authors to use color figures when they will enhance the presentation of the data. The cost is $300 for each illustration containing color. (Note: When using the electronic submission system, any figure submitted in color will be reviewed and processed with the understanding that the figure will be published in color.)
Halftones -- $25 per figure
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There is a per-page charge for all published manuscripts, currently $75 per page. Authors unable to pay page charges may apply at the time of submission for a waiver of page charges.Apply for a page charge waiver in your cover letter at the time of submission. Applications must be endorsed by a senior institutional official.Page waivers will not be granted once a manuscript has been accepted.
As a condition of publication, all authors must transfer copyright to the American Society of Biochemistry and Molecular Biology, Inc. Manuscripts submitted under multiple authorship are reviewed on the assumption that all listed authors concur in the submission and that the final version of the manuscript has been seen and approved by all authors.
Allegations of fraud or misconduct be they violations of the standard norms for publishing original research; publication without approval of all authors, plagiarism, re-publication of data used previously without acknowledgement, or inappropriate graphics manipulation will be investigated thoroughly. If, after due process involving the JBC editors, editorial staff and the ASBMB Publications Committee, a paper is found to contain ethical violations the paper will be rejected or withdrawn and the matter referred to institutional officials.
Authors of papers published in the JOURNAL are obligated to honor any reasonable request by qualified investigators for unique propagative materials, such as cell lines, hybridomas, DNA clones, and organisms that are described in the paper. The primary data obtained from genome- or proteome- scale analyses must be submitted for review in electronic form and, if the manuscript is accepted, must be published as Supplemental Information in JBC On-line. If computer software programs are developed and used in submitted manuscripts, the programs must be made available to the reviewer upon request. The source code or the program must be made available, either commercially or in downloadable form from the authors, if the manuscript is accepted for publication. The Editors may deny further publication rights in the Journal to authors unwilling to abide by these principles.
It is the responsibility of the Editor-in-Chief, the Associate Editors, and the Editorial Board to determine the suitability of a manuscript for publication. After receipt of a manuscript by the Editor, it is sent to an Associate Editor who usually assigns it to a member of the Editorial Board. The Board member then makes a recommendation for acceptance, revision, or declination based on the scientific merit and technical quality of the studies reported. Referees may be consulted when additional expertise is required.
All Board members and referees who review a manuscript remain unknown to the authors. Every manuscript is treated by the Editors and referees as privileged information, and they are instructed to exclude themselves from review of any manuscript that might involve a conflict of interest or the appearance thereof.
The primary criteria for judging the acceptability of a manuscript are its novelty and scientific importance. Manuscripts judged lacking in these respects will be declined, even if the experimental work appears technically sound. This policy permits declination of a manuscript solely on the Editorial Board’s judgement that the studies reported are not sufficiently novel or important to merit publication in the JOURNAL.
The Editors use a set of guidelines, set forth below, to assist them in making editorial decisions. Manuscripts accepted as Regular Papers are expected to fall within the top 15 percent of all work published in a particular field. Manuscripts accepted as Accelerated Publications are expected to fall within the top 5 percent of all work published in a particular field.
Manuscripts of the following types will be declined without full review because they do not satisfy the guidelines for publication in the Journal.
Manuscripts that report contributions that are judged to be of insufficient importance or novelty or that fail to provide mechanistic insights into biological processes at the biochemical or molecular level. In the absence of novelty and biochemical importance, medical relevance or pharmacological potential alone will not be considered sufficient to justify publication.
Manuscripts that report development of a new technique without also reporting novel and significant biochemical insights.
Manuscripts reporting an amino acid or nucleotide sequence, or the cloning and expression of a gene, if the same protein or gene from another tissue or organism has already been described.
Manuscripts reporting the cloning and sequencing of a novel gene without providing experimental evidence for its biological function.
Manuscripts describing just the purification and/or characterization of an enzyme or protein if the same enzyme or protein has been described from another tissue or organism.
Manuscripts that describe biochemical analyses of interactions between macromolecules or between macromolecules and small ligands OR results of two-hybrid screens, co-immunoprecipitation, gel mobility shift, or related assays without providing information about the functional consequences of the interactions.
Manuscripts that rely solely on the use of protein over-expression in transfected cells or the use of recombinant proteins to demonstrate protein-protein interactions, without providing evidence that such interactions occur between protein partners expressed from the endogenous genes in relevant cell lines or tissues.
Manuscripts that focus on identifying regulatory elements and the proteins that bind them without providing new insights into molecular mechanisms of gene expression or regulatory protein function.
Manuscripts that simply identify methylated sites in a gene or promoter, or demonstrate that the methylation status of a gene correlates with gene expression, without providing novel information about how methylation is controlled or how methylation controls gene expression.
Manuscripts that merely describe the effects of agents such as drugs, hormones, cytokines, or the effects of the state of differentiation on an "end point" (enzyme activity, protein level, mRNA abundance, or descriptive aspect of a cellular response).
Manuscripts in which reagents are assumed to act specifically without a suitable demonstration or reference documenting their specificity.
Manuscripts that rely solely on the use of pharmacological agents to define a biochemical process.
Manuscripts describing modification of a protein by a well-established process such as glycosylation, phosphorylation, fatty acylation, or prenylation without showing the biological or biochemical significance of the modification or providing novel insights into the mechanism of the modification process.
Manuscripts that report the structure of an oligosaccharide not differing substantially from an oligosaccharide that was described earlier for another glycoconjugate.
Manuscripts reporting that mutation of a protein alters its function without providing clear evidence about the mechanism by which the function is altered.
Manuscripts that use transgenes or knockouts to confirm results reported previously in model systems without adding new mechanistic insight into the processes involved.
Manuscripts that report generation of transgenic or knockout mutants that lack demonstrated phenotypes and/or that fail to provide new insights into biochemical processes.
Manuscripts that describe genome-, metabolome-, or proteome-scale functional analysis by differential display, microarray, mass spectrometry, or other methods without providing novel insight into a biochemical process or its regulation.
Manuscripts describing computational analyses in structural biology, enzyme kinetics, systems biology and bioinformatics that do not provide significant new insights into biochemical processes.
Manuscripts describing studies of either cell cycle or apoptosis that use inadequate FACS analysis procedures (e.g., single parameter DNA histograms of a single time point) to establish biological states.
Manuscripts that report experiments using RNA interference (RNAi) without appropriate controls as described in Nature Cell Biology 5, 489-490 (2003). Such controls may include use of siRNAs with one or two nucleotide changes from the target sequence, multiple siRNAs for the same target, and rescue by expression of target sequences refractory to siRNA.
Manuscripts that report results that are not accompanied by explicit analyses of experimental uncertainty and reproducibility. Acceptable analyses of experimental uncertainty of numerical data include the standard deviation, the standard error, or the mean and range of values obtained from replicate experiments, as appropriate.
Bar graphs and scatter plots (X,Y plots) should include error bars and the meaning of the error bars should be defined in the text. Plots that include lines that represent computed fits of experimental data to equations must be accompanied by the equation used to calculate the fit, the values of the fit parameters, and statistics that characterize the quality of the fit.
Last Updated: 23 April 2008
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