Searching journal content for Bradley T. Hyman in author.

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  1. Molecular Bases of Disease - Protein Structure and Folding:
    • Eleanna Kara,
    • Jordan D. Marks,
    • Zhanyun Fan,
    • Jacob A. Klickstein,
    • Allyson D. Roe,
    • Kelly A. Krogh,
    • Susanne Wegmann,
    • Masato Maesako,
    • Christina C. Luo,
    • Ravi Mylvaganam,
    • Oksana Berezovska,
    • Eloise Hudry,
    • and Bradley T. Hyman
    Isoform and cell type-specific structure of Apolipoprotein E lipoparticles as revealed by a novel Forster Resonance Energy Transfer assay J. Biol. Chem. jbc.M117.784264. doi:10.1074/jbc.M117.784264
  2. Molecular Bases of Disease - Neurobiology:
    • Yukiko Hori,
    • Tadafumi Hashimoto,
    • Hidetoshi Nomoto,
    • Bradley T. Hyman,
    • and Takeshi Iwatsubo
    Role of Apolipoprotein E in β-Amyloidogenesis: ISOFORM-SPECIFIC EFFECTS ON PROTOFIBRIL TO FIBRIL CONVERSION OF Aβ IN VITRO AND BRAIN Aβ DEPOSITION IN VIVO J. Biol. Chem. 2015 290: 15163-. doi:10.1074/jbc.M114.622209
  3. Neurobiology - Molecular Bases of Disease:
    • Yukiko Hori,
    • Shuko Takeda,
    • Hansang Cho,
    • Susanne Wegmann,
    • Timothy M. Shoup,
    • Kazue Takahashi,
    • Daniel Irimia,
    • David R. Elmaleh,
    • Bradley T. Hyman,
    • and Eloise Hudry
    A Food and Drug Administration-approved Asthma Therapeutic Agent Impacts Amyloid β in the Brain in a Transgenic Model of Alzheimer Disease J. Biol. Chem. 2015 290: 1966-. doi:10.1074/jbc.M114.586602
  4. Neurobiology - Molecular Bases of Disease:
    • Tadafumi Hashimoto,
    • Kenneth W. Adams,
    • Zhanyun Fan,
    • Pamela J. McLean,
    • and Bradley T. Hyman
    Characterization of Oligomer Formation of Amyloid-β Peptide Using a Split-luciferase Complementation Assay J. Biol. Chem. 2011 286: 27081-. doi:10.1074/jbc.M111.257378
  5. Mechanisms of Signal Transduction:
    • Hyang-Sook Hoe,
    • Zhanyan Fu,
    • Alexandra Makarova,
    • Ji-Yun Lee,
    • Congyi Lu,
    • Li Feng,
    • Ahdeah Pajoohesh-Ganji,
    • Yasuji Matsuoka,
    • Bradley T. Hyman,
    • Michael D. Ehlers,
    • Stefano Vicini,
    • Daniel T. S. Pak,
    • and G. William Rebeck
    The Effects of Amyloid Precursor Protein on Postsynaptic Composition and Activity J. Biol. Chem. 2009 284: 8495-. doi:10.1074/jbc.M900141200
  6. Protein Synthesis, Post-Translational Modification, and Degradation:
    • Julie E. Tetzlaff,
    • Preeti Putcha,
    • Tiago F. Outeiro,
    • Alexander Ivanov,
    • Oksana Berezovska,
    • Bradley T. Hyman,
    • and Pamela J. McLean
    CHIP Targets Toxic α-Synuclein Oligomers for Degradation J. Biol. Chem. 2008 283: 17962-. doi:10.1074/jbc.M802283200
  7. Mechanisms of Signal Transduction:
    • Hyang-Sook Hoe,
    • S. Sakura Minami,
    • Alexandra Makarova,
    • Jiyeon Lee,
    • Bradley T. Hyman,
    • Yasuji Matsuoka,
    • and G. William Rebeck
    Fyn Modulation of Dab1 Effects on Amyloid Precursor Protein and ApoE Receptor 2 Processing J. Biol. Chem. 2008 283: 6288-. doi:10.1074/jbc.M704140200
  8. Genomics, Proteomics, and Bioinformatics:
    • Minji Kim,
    • Louis B. Hersh,
    • Malcolm A. Leissring,
    • Martin Ingelsson,
    • Toshifumi Matsui,
    • Wesley Farris,
    • Alice Lu,
    • Bradley T. Hyman,
    • Dennis J. Selkoe,
    • Lars Bertram,
    • and Rudolph E. Tanzi
    Decreased Catalytic Activity of the Insulin-degrading Enzyme in Chromosome 10-Linked Alzheimer Disease Families J. Biol. Chem. 2007 282: 7825-. doi:10.1074/jbc.M609168200
  9. Protein Synthesis, Post-Translation Modification, and Degradation:
    • Mikko Hiltunen,
    • Alice Lu,
    • Anne V. Thomas,
    • Donna M. Romano,
    • Minji Kim,
    • Phill B. Jones,
    • Zhongcong Xie,
    • Maria Z. Kounnas,
    • Steven L. Wagner,
    • Oksana Berezovska,
    • Bradley T. Hyman,
    • Giuseppina Tesco,
    • Lars Bertram,
    • and Rudolph E. Tanzi
    Ubiquilin 1 Modulates Amyloid Precursor Protein Trafficking and Aβ Secretion J. Biol. Chem. 2006 281: 32240-. doi:10.1074/jbc.M603106200
  10. Molecular Basis of Cell and Developmental Biology:
    • Anne V. Thomas,
    • Lauren Herl,
    • Robert Spoelgen,
    • Mikko Hiltunen,
    • Phill B. Jones,
    • Rudolph E. Tanzi,
    • Bradley T. Hyman,
    • and Oksana Berezovska
    Interaction between Presenilin 1 and Ubiquilin 1 as Detected by Fluorescence Lifetime Imaging Microscopy and a High-throughput Fluorescent Plate Reader J. Biol. Chem. 2006 281: 26400-. doi:10.1074/jbc.M601085200
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