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Editors' Picks Highlights - Cell Biology - Glycobiology and Extracellular Matrices:

M. Osman Sheikh and
Lance Wells

Whoa man! Unexpected protein O-mannosylation pathways in mammals J. Biol. Chem. 2017 292: 11599-. doi:10.1074/jbc.H117.794487

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Gene Regulation:

Abir Yamak,
Romain O. Georges,
Massomeh Sheikh-Hassani,
Martin Morin,
Hiba Komati,
and Mona Nemer

Novel Exons in the Tbx5 Gene Locus Generate Protein Isoforms with Distinct Expression Domains and Function J. Biol. Chem. 2015 290: 6844-. doi:10.1074/jbc.M114.634451

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Glycobiology and Extracellular Matrices - Enzymology:

Christopher M. Schafer,
M. Osman Sheikh,
Dongmei Zhang,
and Christopher M. West

Novel Regulation of Skp1 by the Dictyostelium AgtA α-Galactosyltransferase Involves the Skp1-binding Activity of Its WD40 Repeat Domain J. Biol. Chem. 2014 289: 9076-. doi:10.1074/jbc.M113.528679

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Signal Transduction - Cell Biology:

Jie An,
Jingxue Shi,
Qin He,
Ki Lui,
Yuxin Liu,
Ying Huang,
and M. Saeed Sheikh

CHCM1/CHCHD6, Novel Mitochondrial Protein Linked to Regulation of Mitofilin and Mitochondrial Cristae Morphology J. Biol. Chem. 2012 287: 7411-. doi:10.1074/jbc.M111.277103

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Cell Biology - Protein Synthesis and Degradation:

Lingyan Jiang,
Rong Rong,
M. Saeed Sheikh,
and Ying Huang

Cullin-4A·DNA Damage-binding Protein 1 E3 Ligase Complex Targets Tumor Suppressor RASSF1A for Degradation during Mitosis J. Biol. Chem. 2011 286: 6971-. doi:10.1074/jbc.M110.186494

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Mechanisms of Signal Transduction:

Chad A. Corcoran,
JoAnne Montalbano,
Hong Sun,
Qin He,
Ying Huang,
and M. Saeed Sheikh

Identification and Characterization of Two Novel Isoforms of Pirh2 Ubiquitin Ligase That Negatively Regulate p53 Independent of RING Finger Domains J. Biol. Chem. 2009 284: 21955-. doi:10.1074/jbc.M109.024232

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Mechanisms of Signal Transduction:

JoAnne Montalbano,
Ki Lui,
M. Saeed Sheikh,
and Ying Huang

Identification and Characterization of RBEL1 Subfamily of GTPases in the Ras Superfamily Involved in Cell Growth Regulation J. Biol. Chem. 2009 284: 18129-. doi:10.1074/jbc.M109.009597

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Mechanisms of Signal Transduction:

JoAnne Montalbano,
Weixin Jin,
M. Saeed Sheikh,
and Ying Huang

RBEL1 Is a Novel Gene That Encodes a Nucleocytoplasmic Ras Superfamily GTP-binding Protein and Is Overexpressed in Breast Cancer J. Biol. Chem. 2007 282: 37640-. doi:10.1074/jbc.M704760200

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MECHANISMS OF SIGNAL TRANSDUCTION:

Ying Huang,
Dorothy Hutter,
Yusen Liu,
Xiantao Wang,
M. Saeed Sheikh,
Andrew M-L. Chan,
and Nikki J. Holbrook

Transforming Growth Factor-β1 Suppresses Serum Deprivation-induced Death of A549 Cells through Differential Effects on c-Jun and JNK Activities J. Biol. Chem. 2000 275: 18234-. doi:10.1074/jbc.M909431199

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NUCLEIC ACIDS, PROTEIN SYNTHESIS, AND MOLECULAR GENETICS:

M. Saeed Sheikh,
Ester Fernandez-Salas,
Myounghee Yu,
Arif Hussain,
Jonathan D. Dinman,
Stuart W. Peltz,
Ying Huang,
and Albert J. Fornace, Jr.

Cloning and Characterization of a Human Genotoxic and Endoplasmic Reticulum Stress-inducible cDNA That Encodes Translation Initiation Factor 1(eIF1^A121/SUI1) J. Biol. Chem. 1999 274: 16487-. doi:10.1074/jbc.274.23.16487

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