Searching journal content for copper (as phrase) in full text.

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  1. Protein Structure and Folding - Molecular Bases of Disease:
    • Patrick Constantinescu,
    • Rebecca A Brown,
    • Amy R Wyatt,
    • Marie Ranson,
    • and Mark R Wilson
    Amorphous protein aggregates stimulate plasminogen activation, leading to release of cytotoxic fragments that are clients for extracellular chaperones J. Biol. Chem. jbc.M117.786657. doi:10.1074/jbc.M117.786657
    ...activation is stimulated by prion protein and regulated in a copper-dependent manner. Biochemistry 41, 6891-6896 15. Machovich, R., and Owen, W. G. (1997) Denatured proteins as cofactors for plasminogen activation. Arch. Biochem. Biophys. 344, 343-349 16. Radcliffe, R. (1983) A critical role of lysine ~~~
  2. Bioenergetics - Methods and Resources:
    • Edward T. Chouchani,
    • Andrew M. James,
    • Carmen Methner,
    • Victoria R. Pell,
    • Tracy A. Prime,
    • Brian K. Erikson,
    • Marleen Forkink,
    • Gigi Y. Lau,
    • Thomas P. Bright,
    • Katja E. Menger,
    • Ian M. Fearnley,
    • Thomas Krieg,
    • and Michael P. Murphy
    Identification and Quantification of Protein S-nitrosation by Nitrite in the Mouse Heart during Ischemia J. Biol. Chem. jbc.M117.798744. doi:10.1074/jbc.M117.798744
    ...., and Feelisch, M. (2006) Measurement of nitric oxide levels in the red cell: validation of tri-iodide-based chemiluminescence with acid-sulfanilamide pretreatment. J. Biol. Chem. 281, 26994-27002 28. Wang, X., Kettenhofen, N. J., Shiva, S., Hogg, N., and Gladwin, M. T. (2008) Copper dependence of the biotin ~~~
  3. Enzymology - Molecular Biophysics:
    • Moritz Senger,
    • Sven T. Stripp,
    • and Basem Soboh
    Proteolytic cleavage orchestrates cofactor insertion and protein assembly in [NiFe]-hydrogenase biosynthesis J. Biol. Chem. 2017 292: 11670-. doi:10.1074/jbc.M117.788125
    ...analysis determined by inductively coupled plasma mass spectrometry (ICPMS) showed that the GDE complex contained 4.4 iron ions/mol of ternary complex, whereasHybGcontained substoichiometric amounts of iron (0.3 mol of iron/mol of HybG). The amount of nickel, copper, cobalt, and zinc was below ~~~
  4. Microbiology - Developmental Biology:
    • Samuel Plante,
    • Vincent Normant,
    • Karla M. Ramos-Torres,
    • and Simon Labbé
    Cell-surface copper transporters and superoxide dismutase 1 are essential for outgrowth during fungal spore germination J. Biol. Chem. 2017 292: 11896-. doi:10.1074/jbc.M117.794677
    ...growth, but the requirements for spore germination are incompletely understood. Here, we show that copper is essential for spore germination in Schizosaccharomyces pombe. Germinating spores develop a single germ tube that emerges from the outer sporewall in a process called outgrowth.Under low-copper ~~~
  5. Microbiology - Molecular Bases of Disease:
    • Heather K. Kroh,
    • Ramyavardhanee Chandrasekaran,
    • Kim Rosenthal,
    • Rob Woods,
    • Xiaofang Jin,
    • Melanie D. Ohi,
    • Andrew C. Nyborg,
    • G. Jonah Rainey,
    • Paul Warrener,
    • Benjamin W. Spiller,
    • and D. Borden Lacy
    Use of a neutralizing antibody helps identify structural features critical for binding of Clostridium difficile toxin TcdA to the host cell surface J. Biol. Chem. jbc.M117.781112. doi:10.1074/jbc.M117.781112
    ...buffer to 6 ng/L toxin. Samples were immediately applied to glow discharged, carbon-coated copper grids for negative staining with 0.75% uranyl formate (42). Initial micrographs of TcdA in complex with either PA50 mAb or Fab were collected at 44K magnification on a Morgagni (100 keV; FEI) transmission ~~~
  6. Metabolism - Enzymology:
    • Umakant Sahu,
    • Hunsur R Vinod Kumar,
    • Shankar S Kapnoor,
    • Raghu Bhagavat,
    • Nagasuma Chandra,
    • and Pundi N. Rangarajan
    Methionine synthase is localized to the nucleus in Pichia pastoris and Candida albicans and to the cytoplasm in Saccharomyces cerevisiae J. Biol. Chem. jbc.M117.783019. doi:10.1074/jbc.M117.783019
    ...copper ~~~
  7. Protein Structure and Folding - Molecular Biophysics:
    • Daniel Calles-Garcia,
    • Meng Yang,
    • Naoto Soya,
    • Roberto Melero,
    • Marie Ménade,
    • Yukishige Ito,
    • Javier Vargas,
    • Gergely L. Lukacs,
    • Justin M. Kollman,
    • Guennadi Kozlov,
    • and Kalle Gehring
    Single-particle electron microscopy structure of UDP-glucose:glycoprotein glucosyltransferase suggests a selectivity mechanism for misfolded proteins J. Biol. Chem. 2017 292: 11499-. doi:10.1074/jbc.M117.789495
    ...to calculate a theoretical X-ray scattering curve from an input EM model. EM sample preparation and image acquisition DmUGGT (12 ng/l) andPcUGGT (7.5 ng/l) proteinswere applied onto negatively glow-discharged carbon-coated grids (400-mesh copper grids) for 60 s, and excess protein was removed by blotting ~~~
  8. Cell Biology - Metabolism:
    • Brandon L. Logeman,
    • L. Kent Wood,
    • Jaekwon Lee,
    • and Dennis J. Thiele
    Gene duplication and neo-functionalization in the evolutionary and functional divergence of the metazoan copper transporters Ctr1 and Ctr2 J. Biol. Chem. 2017 292: 11531-. doi:10.1074/jbc.M117.793356
    ..., and Molecular Genetics andMicrobiology, Duke University School of Medicine, Durham, North Carolina 27710 and the Department of Biochemistry and Redox Biology Center, University of Nebraska, Lincoln, Nebraska 68588 Edited by Ruma Banerjee Copper is an essential element for proper organismal development ~~~
  9. Molecular Bases of Disease - Developmental Biology:
    • Juliana Marulanda,
    • Hazem Eimar,
    • Marc D. McKee,
    • Michelle Berkvens,
    • Valentin Nelea,
    • Hassem Roman,
    • Teresa Borrás,
    • Faleh Tamimi,
    • Mathieu Ferron,
    • and Monzur Murshed
    Matrix Gla protein deficiency impairs nasal septum growth, causing midface hypoplasia J. Biol. Chem. 2017 292: 11400-. doi:10.1074/jbc.M116.769802
    ...copper X-ray tube (wavelength, 1.54056 Å) and a HI-STAR general area detector diffraction system mounted on a vertical – goniometer (Bruker-AXS Inc).Measurements were run in coupled – scan inmicrobeam analysismode (50-mX-ray beam spot size). The samples examined were the same as those used for elec ~~~
  10. Metabolism - Gene Regulation:
    • Mark E. Corkins,
    • Stevin Wilson,
    • Jean-Christophe Cocuron,
    • Ana P. Alonso,
    • and Amanda J. Bird
    The gluconate shunt is an alternative route for directing glucose into the pentose phosphate pathway in fission yeast J. Biol. Chem. jbc.M117.798488. doi:10.1074/jbc.M117.798488
    ...., and Culotta, V. C. (1996) The yeast copper/zinc superoxide dismutase and the pentose phosphate pathway play overlapping roles in oxidative stress protection. J Biol Chem 271, 28831-28836 Zinc-dependent regulation of the Gcd1 glucose dehydrogenase 12 31. Ng, C. Y., Jung, M. Y., Lee, J., and Oh, M. K. (2012 ~~~
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