Searching journal content for metabolic tracer (as phrase) in full text.

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  1. Accelerated Communications - Metabolism - Bioenergetics:
    • Melanie R. McReynolds,
    • Wenqing Wang,
    • Lauren M. Holleran,
    • and Wendy Hanna-Rose
    Uridine monophosphate synthetase enables eukaryotic de novo NAD+ biosynthesis from quinolinic acid J. Biol. Chem. 2017 292: 11147-. doi:10.1074/jbc.C117.795344
    ...that the kynurenine pathway contributes toNAD homeostasis inC. elegans perhaps by contributing to biosynthetic capacity. To directly test whether de novoNAD synthesis from tryptophan via QA occurs, we used isotopically labeled metabolic tracers. After short-term supplementation of cultures with deuterium-labeled Trp ~~~
  2. Metabolism - Neurobiology:
    • Jennifer R. Chao,
    • Kaitlen Knight,
    • Abbi L. Engel,
    • Connor Jankowski,
    • Yekai Wang,
    • Megan A. Manson,
    • Haiwei Gu,
    • Danijel Djukovic,
    • Daniel Raftery,
    • James B. Hurley,
    • and Jianhai Du
    Human Retinal Pigment Epithelium Cells prefer proline as a nutrient and transport metabolic intermediates to the retinal side J. Biol. Chem. jbc.M117.788422. doi:10.1074/jbc.M117.788422
    ...intermediates to the apical side to nourish the outer retina. amino acid metabolic regulation metabolic tracer metabolism metabolomics retina retinal metabolism Human Retinal Pigment Epithelium Cells prefer proline as a nutrient and transport metabolic intermediates to the retinal side Jennifer R ~~~
  3. Metabolism:
    • Rachel J. Perry,
    • Candace B. Borders,
    • Gary W. Cline,
    • Xian-Man Zhang,
    • Tiago C. Alves,
    • Kitt Falk Petersen,
    • Douglas L. Rothman,
    • Richard G. Kibbey,
    • and Gerald I. Shulman
    Propionate Increases Hepatic Pyruvate Cycling and Anaplerosis and Alters Mitochondrial Metabolism J. Biol. Chem. 2016 291: 12161-. doi:10.1074/jbc.M116.720631
    ...using [1,2,3-13C3]propionate as a metabolic tracer (15). Such high rates of pyruvate cycling would use a significant fraction of the ATP available to the hepatocyte, placing it in a metabolically precarious position. We hypothesized that propionate itself, when used at the concentrations necessary ~~~
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  4. Metabolism - Cell Biology:
    • Zachary J. Reitman,
    • Christopher G. Duncan,
    • Ethan Poteet,
    • Ali Winters,
    • Liang-Jun Yan,
    • David M. Gooden,
    • Ivan Spasojevic,
    • Laszlo G. Boros,
    • Shao-Hua Yang,
    • and Hai Yan
    Cancer-associated Isocitrate Dehydrogenase 1 (IDH1) R132H Mutation and d-2-Hydroxyglutarate Stimulate Glutamine Metabolism under Hypoxia J. Biol. Chem. 2014 289: 23318-. doi:10.1074/jbc.M114.575183
    ...metabolic tracer ~~~
  5. Reports - Metabolism - Molecular Bases of Disease:
    • Romana Stark,
    • Fitsum Guebre-Egziabher,
    • Xiaojian Zhao,
    • Colleen Feriod,
    • Jianying Dong,
    • Tiago C. Alves,
    • Simona Ioja,
    • Rebecca L. Pongratz,
    • Sanjay Bhanot,
    • Michael Roden,
    • Gary W. Cline,
    • Gerald I. Shulman,
    • and Richard G. Kibbey
    A Role for Mitochondrial Phosphoenolpyruvate Carboxykinase (PEPCK-M) in the Regulation of Hepatic Gluconeogenesis J. Biol. Chem. 2014 289: 7257-. doi:10.1074/jbc.C113.544759
    ...and fed glucose homeostasis and this mitochondrial GTP dependent pathway should be reconsidered for its involvement in both normal and diabetic metabolism Diabetes Gluconeogenesis Glyceroneogenesis GTPase Intermediary Metabolism Metabolic Regulation Metabolic Tracers Metabolism Mitochondrial Metabolism ~~~
  6. Glycobiology and Extracellular Matrices - Metabolism:
    • Mie Ichikawa,
    • David A. Scott,
    • Marie-Estelle Losfeld,
    • and Hudson H. Freeze
    The Metabolic Origins of Mannose in Glycoproteins J. Biol. Chem. 2014 289: 6751-. doi:10.1074/jbc.M113.544064
    ...of mannose contribution and its metabolic fate provides information that can help bolster therapeutic strategies for treating glycosylation disorders with exogenous mannose GC MS Genetic Diseases Glucose Metabolism Glycoconjugate Metabolic Tracers Introduction Both glucose and mannose can contribute mannose ~~~
  7. Gene Regulation - Metabolism:
    • Rafaela Ruiz,
    • Victoria Jideonwo,
    • Miwon Ahn,
    • Sneha Surendran,
    • Vincent S. Tagliabracci,
    • Yongyong Hou,
    • Aisha Gamble,
    • Janos Kerner,
    • José M. Irimia-Dominguez,
    • Michelle A. Puchowicz,
    • Anna DePaoli-Roach,
    • Charles Hoppel,
    • Peter Roach,
    • and Núria Morral
    Sterol Regulatory Element-binding Protein-1 (SREBP-1) Is Required to Regulate Glycogen Synthesis and Gluconeogenic Gene Expression in Mouse Liver J. Biol. Chem. 2014 289: 5510-. doi:10.1074/jbc.M113.541110
    ...Metabolic Tracer Study Three weeks after gAd shSREBP1 or gAd shSCR adenoviral vector administration db db mice were given 2H2O intraperitoneally 21 4 l g of body weight this dose enriches body water content to 3 and fasted for 4 hwith free access towater Animals were euthanized and serum and liver ~~~
  8. Microbiology - Metabolism:
    • James B. McKinlay,
    • Yasuhiro Oda,
    • Martin Rühl,
    • Amanda L. Posto,
    • Uwe Sauer,
    • and Caroline S. Harwood
    Non-growing Rhodopseudomonas palustris Increases the Hydrogen Gas Yield from Acetate by Shifting from the Glyoxylate Shunt to the Tricarboxylic Acid Cycle J. Biol. Chem. 2014 289: 1960-. doi:10.1074/jbc.M113.527515
    ...metabolic tracer ~~~
  9. Metabolism - Microbiology:
    • José M. Pastor,
    • Vicente Bernal,
    • Manuel Salvador,
    • Montserrat Argandoña,
    • Carmen Vargas,
    • Laszlo Csonka,
    • Ángel Sevilla,
    • José L. Iborra,
    • Joaquín J. Nieto,
    • and Manuel Cánovas
    Role of Central Metabolism in the Osmoadaptation of the Halophilic Bacterium Chromohalobacter salexigens J. Biol. Chem. 2013 288: 17769-. doi:10.1074/jbc.M113.470567
    ...metabolic tracer ~~~
  10. Metabolism - Bioenergetics:
    • Paulo A. Gameiro,
    • Laura A. Laviolette,
    • Joanne K. Kelleher,
    • Othon Iliopoulos,
    • and Gregory Stephanopoulos
    Cofactor Balance by Nicotinamide Nucleotide Transhydrogenase (NNT) Coordinates Reductive Carboxylation and Glucose Catabolism in the Tricarboxylic Acid (TCA) Cycle J. Biol. Chem. 2013 288: 12967-. doi:10.1074/jbc.M112.396796
    ...metabolic tracer ~~~
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