Searching journal content for metal homeostasis (as phrase) in full text.

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  1. Microbiology - Developmental Biology:
    • Samuel Plante,
    • Vincent Normant,
    • Karla M. Ramos-Torres,
    • and Simon Labbé
    Cell-surface copper transporters and superoxide dismutase 1 are essential for outgrowth during fungal spore germination J. Biol. Chem. 2017 292: 11896-. doi:10.1074/jbc.M117.794677
    ...metal homeostasis superoxide dismutase (SOD) yeast yeast physiology copper transporters fission yeast spore germination Introduction Schizosaccharomyces pombe cell proliferation generally occurs in a haploid state through rounds of mitotic cell divisions under nutrient-rich conditions. In contrast, ~~~
  2. Cell Biology - Metabolism:
    • Brandon L. Logeman,
    • L. Kent Wood,
    • Jaekwon Lee,
    • and Dennis J. Thiele
    Gene duplication and neo-functionalization in the evolutionary and functional divergence of the metazoan copper transporters Ctr1 and Ctr2 J. Biol. Chem. 2017 292: 11531-. doi:10.1074/jbc.M117.793356
    ...metal homeostasis yeast Ctr1 Ctr2 Introduction Copper is a critical metal for all forms of eukaryotic life because of its ability to shuttle electrons and cycle between oxidation states, Cu+ and Cu2+, under biologically relevant conditions. As such, this redox property has been harnessed during the ~~~
  3. Minireview - Enzymology - Metabolism:
    • F. Peter Guengerich
    MINIREVIEW PROLOGUE Introduction: Metals in Biology 2017: Iron transport, storage, and the ramifications J. Biol. Chem. jbc.R117.801332. doi:10.1074/jbc.R117.801332
    ....guengerich@vanderbilt.edu Keywords: Iron, iron metabolism, metals, metal transport, metal homeostasis ABSTRACT In this tenth Thematic Series in Metals in Biology, five Minireviews deal with aspects of iron metabolism. A number of important proteins control iron homeostasis, including hepcidin and ferroportin, in various cells ~~~
  4. Minireviews - RNA - Gene Regulation:
    • Joseph E. Wedekind,
    • Debapratim Dutta,
    • Ivan A. Belashov,
    • and Jermaine L. Jenkins
    Metalloriboswitches: RNA-based inorganic ion sensors that regulate genes J. Biol. Chem. 2017 292: 9441-. doi:10.1074/jbc.R117.787713
    ...metal homeostasis Salmonella enterica transcription regulation riboswitch Introduction Riboswitches are highly structured RNA motifs often located in the 5′-leader sequences of bacterial mRNAs ( 1 – 3 ). A riboswitch recognizes its cognate effector by a conserved aptamer domain, which elicits confor ~~~
  5. Protein Structure and Folding - Neurobiology:
    • Urška Slapšak,
    • Giulia Salzano,
    • Ladan Amin,
    • Romany N. N. Abskharon,
    • Gregor Ilc,
    • Blaž Zupančič,
    • Ivana Biljan,
    • Janez Plavec,
    • Gabriele Giachin,
    • and Giuseppe Legname
    The N Terminus of the Prion Protein Mediates Functional Interactions with the Neuronal Cell Adhesion Molecule (NCAM) Fibronectin Domain J. Biol. Chem. 2016 291: 21857-. doi:10.1074/jbc.M116.743435
    ...receptor regulation (14, 15), and brain metal homeostasis (16). Putative functions are based on PrPC-interacting molecules present on the cell surface, such as the 37-kDa/67-kDa laminin receptor, the stress-inducible protein 1, and vitronectin (1719). Among the different PrPC protein interactors ~~~
  6. Minireviews - Molecular Biophysics - Cell Biology:
    • Daiana A. Capdevila,
    • Jiefei Wang,
    • and David P. Giedroc
    Bacterial Strategies to Maintain Zinc Metallostasis at the Host-Pathogen Interface J. Biol. Chem. 2016 291: 20858-. doi:10.1074/jbc.R116.742023
    ...enlisted to re-establish homeostasis by repressing uptake and activating efflux.View larger version: In this window In a new window FIGURE 2. A, graphical representation of the set-point model for metal homeostasis. In this model, the metal affinity for individual or pairs of metal sensor proteins (red ~~~
  7. Membrane Biology:
    • Yukina Nishito,
    • Natsuko Tsuji,
    • Hitomi Fujishiro,
    • Taka-aki Takeda,
    • Tomohiro Yamazaki,
    • Fumie Teranishi,
    • Fumiko Okazaki,
    • Ayu Matsunaga,
    • Karin Tuschl,
    • Rajini Rao,
    • Satoshi Kono,
    • Hiroaki Miyajima,
    • Hiroshi Narita,
    • Seiichiro Himeno,
    • and Taiho Kambe
    Direct Comparison of Manganese Detoxification/Efflux Proteins and Molecular Characterization of ZnT10 Protein as a Manganese Transporter J. Biol. Chem. 2016 291: 14773-. doi:10.1074/jbc.M116.728014
    ...-targeting/re-expression strategies (2830). This system is useful to explore metal homeostasis and membrane transport protein functions in vertebrate cells because DT40 cells have a similar homeostatic regulation system of metals to that of mammalian cells and allow efficient gene disruption because of their high homologous ~~~
  8. Cell Biology - Metabolism:
    • Helena Öhrvik,
    • Brandon Logeman,
    • Boris Turk,
    • Thomas Reinheckel,
    • and Dennis J. Thiele
    Cathepsin Protease Controls Copper and Cisplatin Accumulation via Cleavage of the Ctr1 Metal-binding Ectodomain J. Biol. Chem. 2016 291: 13905-. doi:10.1074/jbc.M116.731281
    ...-mediated Cu+ and cisplatin uptake and identify the cathepsin L and B proteases as new components of the metal homeostasis machinery that are amenable to pharmacological manipulation. ChemicalsProtease inhibitors, including TIMP-2 and -3 (R&D Systems), TAPI-2, cathepsin L inhibitor III (benzyloxycarbonyl FY ~~~
  9. Molecular Biophysics:
    • Melody Handali,
    • Hridindu Roychowdhury,
    • Durga P. Neupane,
    • and Erik T. Yukl
    AztD, a Periplasmic Zinc Metallochaperone to an ATP-binding Cassette (ABC) Transporter System in Paracoccus denitrificans J. Biol. Chem. 2015 290: 29984-. doi:10.1074/jbc.M115.684506
    ...chaperones is linked to zinc homeostasis in all kingdoms of life BMC Genomics 10 470 10 Sydor A M Jost M Ryan K S Turo K E Douglas C D Drennan C L andZamble D B 2013 Metal binding properties ofEscherichia coli YjiA a member of the metal homeostasis associated COG0523 family ~~~
  10. Molecular Bases of Disease - Molecular Biophysics:
    • Joseph D. Barritt and
    • John H. Viles
    Truncated Amyloid-β(11–40/42) from Alzheimer Disease Binds Cu2+ with a Femtomolar Affinity and Influences Fiber Assembly J. Biol. Chem. 2015 290: 27791-. doi:10.1074/jbc.M115.684084
    ...metal homeostasis N truncation and high affinity copper binding Angew Chem Int Ed Engl 54 10460 10464 78 Alies B Bijani C Sayen S Guillon E Faller P and Hureau C 2012 Copper coordination to native N terminally modified versus full length amyloid second sphere effects d ~~~
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