Searching journal content for tryptophan (as phrase) in full text.

Displaying results 1-10 of 17604
For checked items
  1. Protein Structure and Folding - Microbiology:
    • Koree W. Ahn and
    • Michael J. Root
    Complex interplay of kinetic factors governs the synergistic properties of HIV-1 entry inhibitors J. Biol. Chem. jbc.M117.791731. doi:10.1074/jbc.M117.791731
    ...tryptophan and tyrosine in proteins, Biochemistry 6(7), 1948-1954. 71. Chen, B. K., Saksela, K., Andino, R., and Baltimore, D. (1994) Distinct modes of human immunodeficiency virus type 1 proviral latency revealed by superinfection of nonproductively infected cell lines with recombinant luciferase-e ~~~
  2. Enzymology - Protein Structure and Folding:
    • David L. Nelson,
    • Gregory A. Applegate,
    • Matthew L. Beio,
    • Danielle L. Graham,
    • and David B. Berkowitz
    Human Serine Racemase Structure/Activity Relationship Studies Provide Mechanistic Insight and Point to Position-84 as a Hotspot for β-Elimination Function J. Biol. Chem. jbc.M117.777904. doi:10.1074/jbc.M117.777904
    ...-ray crystallographic structures of the S. pombe (36), maize (37), mouse (38), rat and human (39) SR enzymes are available. Mammalian SR has a type II eliminase fold reminiscent of the classical PLP-dependent enzyme, tryptophan synthase. Accordingly, it is perhaps not surprising that the enzyme catalyzes both the ~~~
  3. Accelerated Communications - Metabolism - Bioenergetics:
    • Melanie R. McReynolds,
    • Wenqing Wang,
    • Lauren M. Holleran,
    • and Wendy Hanna-Rose
    Uridine monophosphate synthetase enables eukaryotic de novo NAD+ biosynthesis from quinolinic acid J. Biol. Chem. 2017 292: 11147-. doi:10.1074/jbc.C117.795344
    ...phosphoribosyltransferase (QPRTase) is not encoded in its genome, Caenorhabditis elegans are reported to lack a de novo NAD biosynthetic pathway. However, all the genes of the kynurenine pathway required for quinolinic acid (QA) production from tryptophan are present. Thus, we investigated the presence ofde novo NAD ~~~
  4. Cell Biology - Metabolism:
    • Brandon L. Logeman,
    • L. Kent Wood,
    • Jaekwon Lee,
    • and Dennis J. Thiele
    Gene duplication and neo-functionalization in the evolutionary and functional divergence of the metazoan copper transporters Ctr1 and Ctr2 J. Biol. Chem. 2017 292: 11531-. doi:10.1074/jbc.M117.793356
    ...tryptophan ~~~
  5. Lipids:
    • Gil-Soo Han and
    • George M. Carman
    Yeast PAH1-encoded phosphatidate phosphatase controls the expression of CHO1-encoded phosphatidylserine synthase for membrane phospholipid synthesis J. Biol. Chem. jbc.M117.801720. doi:10.1074/jbc.M117.801720
    ...), and thus requires the supplementation of choline or ethanolamine to synthesize PC or PE by the Kennedy pathway (1, 2). Studies with cells lacking Cho1 have revealed that PS is required for protein kinase C function (23, 24), tryptophan transport (25), vacuole function and morphogenesis (26), and directing ~~~
  6. Enzymology - Molecular Bases of Disease:
    • Kednerlin Dornevil,
    • Ian Davis,
    • Andrew J. Fielding,
    • James R. Terrell,
    • Li Ma,
    • and Aimin Liu
    Crosslinking of Dicyclotyrosine by the Cytochrome P450 Enzyme CYP121 from Mycobacterium tuberculosis Proceeds through a Catalytic Shunt Pathway J. Biol. Chem. jbc.M117.794099. doi:10.1074/jbc.M117.794099
    ...tryptophan ~~~
  7. Microbiology - Membrane Biology:
    • Agnes Ulfig,
    • Julia Fröbel,
    • Frank Lausberg,
    • Anne-Sophie Blümmel,
    • Anna Katharina Heide,
    • Matthias Müller,
    • and Roland Freudl
    The h-region of twin-arginine signal peptides supports productive binding of bacterial Tat precursor proteins to the TatBC receptor complex J. Biol. Chem. 2017 292: 10865-. doi:10.1074/jbc.M117.788950
    ...proteins. A replacement of Thr-22 or Gly-25 with a highly hydrophobic isoleucine or valine residue, respectively, evidently resulted in much higher export of the corresponding reporter variants compared with substitutions by less hydrophobic amino acids, i.e. alanine or tryptophan, as indicated by faster ~~~
  8. Editors' Picks - Enzymology - Molecular Bases of Disease:
    • Chunxue Wang,
    • Pradeep S. Pallan,
    • Wei Zhang,
    • Li Lei,
    • Francis K. Yoshimoto,
    • Michael R. Waterman,
    • Martin Egli,
    • and F. Peter Guengerich
    Functional analysis of human cytochrome P450 21A2 variants involved in congenital adrenal hyperplasia J. Biol. Chem. 2017 292: 10767-. doi:10.1074/jbc.M117.792465
    ...in the proper folding of P450 21A2 variants is the proper incorporation of the heme prosthetic group. An approximate index of heme incorporation is provided by theA417/A280 ratio of the purified variants, in that only one of the 12 variants examined involved a change in tryptophan (which would lower A280) (see ~~~
  9. Protein Structure and Folding - Molecular Biophysics:
    • Andressa P. A. Pinto,
    • Humberto M. Pereira,
    • Ana E. Zeraik,
    • Heloisa Ciol,
    • Frederico M. Ferreira,
    • José Brandão-Neto,
    • Ricardo DeMarco,
    • Marcos V. A. S. Navarro,
    • Cristina Risi,
    • Vitold E. Galkin,
    • Richard C. Garratt,
    • and Ana P. U. Araujo
    Filaments and fingers: Novel structural aspects of the single septin from Chlamydomonas reinhardtii J. Biol. Chem. 2017 292: 10899-. doi:10.1074/jbc.M116.762229
    ...of CrSEPT is the most unusual to have been reported to date. The first three strands of the central -sheet are longer than those found in the majority of other septin structures (Fig. 3B), enabling two tryptophan residues from strands 2 and 3 (Trp163 and Trp-173, respectively) to make contact with helix ~~~
  10. Microbiology:
    • Michelle M. Kuttel,
    • Paola Cescutti,
    • Marco Distefano,
    • and Roberto Rizzo
    Fluorescence and NMR spectroscopy together with molecular simulations reveal amphiphilic characteristics of a Burkholderia biofilm exopolysaccharide J. Biol. Chem. 2017 292: 11034-. doi:10.1074/jbc.M117.785048
    ..., from 510 to 450 nm, further indicating ANS complexation by the polysaccharide. In fact, as observed for tryptophan in proteins (25), fluorescent chromophoresmay change their emissionmaximumas a function of the polarity of the environment they experience. We speculate that the ANS-EpolC1576 interaction ~~~
For checked items

Search Results

Next 10 » New Search

Modify Results

Citation format:
Results / page:
Results order:

This search

  • Alert me when new articles matching this search are published
  • Download all citations on this page to my citation manager

Submit your work to JBC.

You'll be in good company.