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  1. ...increases in PG G formation but no change in PG formation Thus cellular peroxide tonemaybe an important determinant of the extent of endocannabinoid oxygenation by PGHS 2 Prostaglandin H synthases PGHSs 2 catalyze the first two steps in the biosynthesis of prostaglandins PGs a class of bioactive...
  2. ...on cardiovascular function 18 The molecular mechanisms of n 3 PUFA action are only partially understood and include changes in membrane structures and gene expression direct interactions with ion channels and alterations in eicosanoid biosynthesis 24 29 EPA and DHA compete with AA for binding and conversion...
  3. ...factors are not known Even though multiple studies suggest that antioxidant therapy prevents LPS induced septic shock 14 16 the mechanisms by which ROS mediate inflammatory signals leading toNF Bactivation are not clearly understood Because lipid peroxidation initiated by ROS generates toxic...
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