Molecular Biophysics
Re: Dudith Pierre-Victor, Howard L. Parnes, Gerald L. Andriole, et al. Prostate Cancer Incidence and Mortality Following a Negative Biopsy in a Population Undergoing PSA Screening. Urology 2021 Jun 26;S0090-4295(21)00539-2
We read with great interest the recent work of Pierre-Victor et al on prostate cancer incidence and mortality in the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial.1 We previously reported, in 2017, on a similar cohort from this trial.2 We studied men in the screening arm who screened positive (via prostate-specific antigen or digital rectal exam) during the first year of the trial, and whose linked biopsy was negative. We found a similar mortality rate after a median follow-up of 12.9 years of 1.1% (vs 1.2% in the present study).The Consequences of Inadvertent Radical Nephrectomy in the Treatment of Upper Tract Urothelial Carcinoma
To determine factors associated with performing inadvertent radical nephrectomy (RN) for upper tract urothelial carcinoma (UTUC), and to assess the impact of radical nephrectomy on overall survival (OS) compared to radical nephroureterectomy (NU).
