Plant Biology
The Potato Nucleotide-binding Leucine-rich Repeat (NLR) Immune Receptor Rx1 Is a Pathogen-dependent DNA-deforming Protein
Background: Direct targets for plant NLR proteins in immune signaling are largely unknown.Results: The Rx1 NLR protein of potato binds and distorts DNA following pathogen perception, resulting in immune activation.Conclusion: DNA is a direct signaling target for a plant NLR immune receptor.Significance: Plant NLR receptors might regulate immune transcriptional responses by directly interacting with plant chromatin.
